|
|
@@ -557,8 +557,9 @@ How much mechanistic detail is needed here? My work doesn't really go into
|
|
|
\begin_layout Standard
|
|
|
Because an allograft comes from a different person, it is genetically distinct
|
|
|
from the rest of the recipient's body.
|
|
|
- Some genetic variants occur in protein coding regions, resulting in protein
|
|
|
- products that differ from the equivalent proteins in the graft recipient's
|
|
|
+ Some genetic variants occur in protein coding regions and affect the polypeptid
|
|
|
+e sequences encoded by the affected genes, resulting in protein products
|
|
|
+ that differ from the equivalent proteins produced by the graft recipient's
|
|
|
own tissue.
|
|
|
As a result, without intervention, the recipient's immune system will eventuall
|
|
|
y identify the graft as foreign tissue and begin attacking it, eventually
|
