Increase overall font size in slides

Snakefile

@@ -377,8 +377,6 @@ rule build_presentation_beamer:
       --pdf-engine=xelatex \
       -o {output.pdf:q} \
       -H {input.extra_preamble:q} \
-      -V theme:{params.theme:q} \
-      -V aspectratio:{params.aspectratio:q} \
       {input.mkdn_file:q}
     '''
 

presentation.mkdn

@@ -1,12 +1,18 @@
-% Bioinformatic analysis of complex, high-throughput genomic and epigenomic data in the context of $\mathsf{CD4}^{+}$ T-cell differentiation and diagnosis and treatment of transplant rejection
-% Ryan C. Thompson \
-  Su Lab \
-  The Scripps Research Institute
-% October 24, 2019
-
-## Organ transplants are a life-saving treatment for many
-
-\LARGE <!-- This should probably be my default bullet point size -->
+---
+title: Bioinformaticanalysis of complex, high-throughput genomic and epigenomic data in the context of $\mathsf{CD4}^{+}$ T-cell differentiation and diagnosis and treatment of transplant rejection
+author: |
+    Ryan C. Thompson \
+    Su Lab \
+    The Scripps Research Institute
+date: October 24, 2019
+theme: Boadilla
+aspectratio: 169
+fontsize: 14pt
+---
+
+## Organ transplants are a life-saving treatment
+
+<!-- \LARGE --> <!-- This should probably be my default bullet point size -->
 
 ::: incremental
 
@@ -21,17 +27,17 @@
 
 [^1]: Source: https://www.organdonor.gov/statistics-stories/statistics.html
 
-## Organ transplants are a life-saving treatment for many
+## Organ transplants are a life-saving treatment
 
 ![Organ donation statistics for the USA in 2018[^2]](graphics/presentation/transplants-organ-CROP-RASTER.png){ height=70% }
 
 [^2]: Source: https://www.organdonor.gov/statistics-stories/statistics.html
 
-## Rejection is an adaptive immune response against a graft
+## Graft rejection is an adaptive immune response
 
 <!-- TODO: Need a graphic for this -->
 
-\LARGE
+<!-- \LARGE -->
 
 ::: incremental
 
@@ -59,7 +65,7 @@
 <!-- TODO: Need a graphic, or maybe a table of common drugs +
 mechanisms, or a diagram for periodic checking. -->
 
-\LARGE
+<!-- \LARGE -->
 
 ::: incremental
 
@@ -165,16 +171,16 @@ Data generated by Sarah Lamere, published in GEO as
 
 ![Flowchart of workflow for data analysis](graphics/CD4-csaw/rulegraphs/rulegraph-all-RASTER300.png)
 
-## Histone modifications are observed on consecutive histones
-
-![Strand cross-correlation plots](graphics/CD4-csaw/csaw/CCF-plots-PAGE2-CROP-RASTER.png)
-
-## Histone modifications are observed on consecutive histones
+## Histone modifications occur on consecutive histones
 
 ![ChIP-seq coverage in IL2 gene[^5]](graphics/presentation/LaMere-thesis-fig3.9-SVG-CROP.png){ height=70% }
 
 [^5]: Sarah LaMere. "Dynamic epigenetic regulation of CD4 T cell activation and memory formation". PhD thesis. TSRI, 2015.
 
+## Histone modifications occur on consecutive histones
+
+![Strand cross-correlation plots](graphics/CD4-csaw/csaw/CCF-plots-PAGE2-CROP-RASTER.png)
+
 ## Finding enriched regions across the genome
 
 * Scan across the genome looking for regions with read coverage above
@@ -189,7 +195,7 @@ Data generated by Sarah Lamere, published in GEO as
 
 ![Enrichment of peaks near promoters](graphics/CD4-csaw/Promoter-Peak-Distance-Profile-PAGE1-CROP-RASTER.png)
 
-## Peaks in promoters are correlated with gene expression
+## Peaks in promoters correlate with gene expression
 
 <!-- TODO: Pull out one column and rotate it -->