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@@ -767,6 +767,10 @@ RNA-seq align+quant method comparison
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\end_layout
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\begin_layout Standard
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+\begin_inset Note Note
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+status open
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+
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+\begin_layout Plain Layout
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\begin_inset Float figure
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wide false
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sideways false
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@@ -1015,6 +1019,11 @@ RNA-seq comparisons
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\end_inset
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+\end_layout
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+
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+\end_inset
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+
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+
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\end_layout
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\begin_layout Itemize
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@@ -1349,6 +1358,10 @@ ChIP-seq peak calling
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\end_layout
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\begin_layout Standard
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+\begin_inset Note Note
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+status open
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+
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+\begin_layout Plain Layout
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\begin_inset Float figure
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wide false
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sideways false
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@@ -1384,10 +1397,6 @@ Peak ranks from SICER peak caller
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\end_inset
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-\end_layout
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-
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-\begin_layout Plain Layout
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-
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\end_layout
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\end_inset
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@@ -1460,7 +1469,8 @@ ible discovery rate (IDR), are shaded accordingly.
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\end_layout
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-\begin_layout Plain Layout
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+\end_inset
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+
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\end_layout
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@@ -1470,20 +1480,8 @@ ible discovery rate (IDR), are shaded accordingly.
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\end_layout
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\begin_layout Standard
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-Figure
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-\begin_inset CommandInset ref
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-LatexCommand ref
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-reference "fig:IDR-rank-consist"
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-plural "false"
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-caps "false"
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-noprefix "false"
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-
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-\end_inset
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-
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- shows the IDR rank-consistency plots for peaks called in an arbitrarily-chosen
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- pair of donors.
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- when the peaks for each donor are ranked according to their scores, SICER
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- produces much more reproducible results between donors.
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+[IDR] When the peaks for each donor are ranked according to their scores,
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+ SICER produces much more reproducible results between donors.
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This is consistent with SICER's stated goal of identifying broad peaks,
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in contrast to MACS, which is designed for identifying sharp peaks.
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Based on this observation, the SICER peak calls were used for all downstream
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@@ -1496,6 +1494,10 @@ ChIP-seq normalization
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\end_layout
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\begin_layout Standard
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+\begin_inset Note Note
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+status open
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+
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+\begin_layout Plain Layout
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\begin_inset Float figure
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wide false
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sideways false
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@@ -1537,6 +1539,11 @@ MA plot of H3K4me2 read counts in 10kb bins for two arbitrary samples.
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\end_inset
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+\end_layout
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+
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+\end_inset
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+
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+
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\end_layout
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\begin_layout Subsection
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@@ -2072,10 +2079,14 @@ LF2 is clearly the RNA-seq batch effect
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\end_layout
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\begin_layout Standard
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+\begin_inset Note Note
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+status open
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+
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+\begin_layout Plain Layout
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\begin_inset Float figure
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wide false
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sideways false
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-status collapsed
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+status open
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\begin_layout Plain Layout
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\align center
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@@ -2115,18 +2126,14 @@ Result of RNA-seq batch-correction using MOFA latent factors
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\end_layout
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-\begin_layout Itemize
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-Attempting to remove the effect of LF2 (Figure
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-\begin_inset CommandInset ref
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-LatexCommand ref
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-reference "fig:mofa-batchsub"
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-plural "false"
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-caps "false"
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-noprefix "false"
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-
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\end_inset
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-) results in batch correction comparable to ComBat (Figure
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+
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+\end_layout
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+
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+\begin_layout Itemize
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+Attempting to remove the effect of LF2 results in batch correction comparable
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+ to ComBat (Figure
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\begin_inset CommandInset ref
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LatexCommand ref
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reference "fig:RNA-PCA-ComBat-batchsub"
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