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- Pathways affected by Interferon Gamma treatment
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- (reduced example)
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- <node TEXT="SPIA pathway test" ID="ID_1769689969" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="biocarta pathway collection" ID="ID_1805838637" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="graphite/biocarta erk and pi-3 kinase are necessary for collagen binding in corneal epithelia: Inhibited, FDR = 0.0627, FWER = 0.0627, PValue = 0.000367" ID="ID_1963726017" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="VCL: 2.48-fold Down; FDR = 5.94e-13; PValue = 9.16e-15; mean CPM = 1013; vinculin" ID="ID_1330078836" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMC1: 2.28-fold Down; FDR = 6.46e-13; PValue = 1.01e-14; mean CPM = 812.1; laminin, gamma 1 (formerly LAMB2)" ID="ID_1812338154" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016591: 4.2-fold Down; FDR = 1.3e-11; PValue = 2.78e-13; mean CPM = 34.90; Uncharacterized protein" ID="ID_1895915603" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016587: 4.92-fold Down; FDR = 1.6e-11; PValue = 3.5e-13; mean CPM = 51.70; Uncharacterized protein" ID="ID_971589038" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNS1: 2.51-fold Down; FDR = 1.03e-10; PValue = 2.68e-12; mean CPM = 434.5; tensin 1" ID="ID_365027110" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYLK: 2.29-fold Down; FDR = 1.02e-06; PValue = 7.45e-08; mean CPM = 128.3; myosin light chain kinase" ID="ID_766879598" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1973935292" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMC2: 2.28-fold Down; FDR = 9.83e-06; PValue = 9.24e-07; mean CPM = 16.99; laminin, gamma 2" ID="ID_630583869" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_190312638" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARHGAP5: 1.36-fold Up; FDR = 0.000133; PValue = 1.7e-05; mean CPM = 130.2; Rho GTPase activating protein 5" ID="ID_1489560571" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCAR1: 1.36-fold Up; FDR = 0.000193; PValue = 2.61e-05; mean CPM = 210.4; breast cancer anti-estrogen resistance 1" ID="ID_839744085" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACTA1: 5.36-fold Down; FDR = 0.000251; PValue = 3.52e-05; mean CPM = 5.880; Uncharacterized protein" ID="ID_226483562" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB2: 1.48-fold Down; FDR = 0.000398; PValue = 5.93e-05; mean CPM = 695.6; laminin, beta 2 (laminin S)" ID="ID_81055279" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZYX: 1.29-fold Down; FDR = 0.00237; PValue = 0.00045; mean CPM = 287.5; Uncharacterized protein" ID="ID_514784989" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHOA: 1.28-fold Down; FDR = 0.00295; PValue = 0.000575; mean CPM = 277.8; ras homolog gene family, member A" ID="ID_1002270378" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLN1: 1.26-fold Down; FDR = 0.0101; PValue = 0.00238; mean CPM = 1820; talin 1" ID="ID_406883440" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1606486276" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB1: 1.23-fold Up; FDR = 0.0759; PValue = 0.0253; mean CPM = 2700; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)" ID="ID_1719828974" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMA4: 1.2-fold Down; FDR = 0.0793; PValue = 0.0266; mean CPM = 624.4; laminin, alpha 4" ID="ID_1773904844" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014969: 1.93-fold Down; FDR = 0.303; PValue = 0.137; mean CPM = 0.9384; Uncharacterized protein" ID="ID_60477055" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB3: 1.6-fold Down; FDR = 0.303; PValue = 0.137; mean CPM = 1.445; laminin, beta 3" ID="ID_1495462090" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PFN1: 1.12-fold Down; FDR = 0.337; PValue = 0.156; mean CPM = 965.8; profilin 1" ID="ID_1039571221" CREATED="1400535622212" MODIFIED="1400535622212"/>
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- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_376544938" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA1: 1.1-fold Down; FDR = 0.57; PValue = 0.308; mean CPM = 422.3; integrin, alpha 1" ID="ID_888154970" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSK: 1.06-fold Down; FDR = 0.673; PValue = 0.386; mean CPM = 45.36; c-src tyrosine kinase" ID="ID_1311390573" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014966: 1.43-fold Down; FDR = 0.72; PValue = 0.423; mean CPM = 0.9009; Uncharacterized protein" ID="ID_1258314574" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MLC1: 1.36-fold Down; FDR = 0.74; PValue = 0.442; mean CPM = 0.9395; megalencephalic leukoencephalopathy with subcortical cysts 1" ID="ID_1685279233" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/biocarta integrin signaling pathway: Inhibited, FDR = 0.0814, FWER = 0.163, PValue = 0.000952" ID="ID_1836579016" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="VCL: 2.48-fold Down; FDR = 5.94e-13; PValue = 9.16e-15; mean CPM = 1013; vinculin" ID="ID_776777780" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMC1: 2.28-fold Down; FDR = 6.46e-13; PValue = 1.01e-14; mean CPM = 812.1; laminin, gamma 1 (formerly LAMB2)" ID="ID_744056602" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016591: 4.2-fold Down; FDR = 1.3e-11; PValue = 2.78e-13; mean CPM = 34.90; Uncharacterized protein" ID="ID_1629591857" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016587: 4.92-fold Down; FDR = 1.6e-11; PValue = 3.5e-13; mean CPM = 51.70; Uncharacterized protein" ID="ID_884831342" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNS1: 2.51-fold Down; FDR = 1.03e-10; PValue = 2.68e-12; mean CPM = 434.5; tensin 1" ID="ID_1263922795" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_479206541" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1470823681" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMC2: 2.28-fold Down; FDR = 9.83e-06; PValue = 9.24e-07; mean CPM = 16.99; laminin, gamma 2" ID="ID_562429055" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCAR1: 1.36-fold Up; FDR = 0.000193; PValue = 2.61e-05; mean CPM = 210.4; breast cancer anti-estrogen resistance 1" ID="ID_1358148615" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACTA1: 5.36-fold Down; FDR = 0.000251; PValue = 3.52e-05; mean CPM = 5.880; Uncharacterized protein" ID="ID_1038806419" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB2: 1.48-fold Down; FDR = 0.000398; PValue = 5.93e-05; mean CPM = 695.6; laminin, beta 2 (laminin S)" ID="ID_929282226" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZYX: 1.29-fold Down; FDR = 0.00237; PValue = 0.00045; mean CPM = 287.5; Uncharacterized protein" ID="ID_1396454041" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHOA: 1.28-fold Down; FDR = 0.00295; PValue = 0.000575; mean CPM = 277.8; ras homolog gene family, member A" ID="ID_595492627" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP1R12B: 1.52-fold Down; FDR = 0.00383; PValue = 0.000782; mean CPM = 15.41; protein phosphatase 1, regulatory (inhibitor) subunit 12B" ID="ID_816251658" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAV1: 1.33-fold Down; FDR = 0.00575; PValue = 0.00125; mean CPM = 228.7; caveolin-1" ID="ID_365275295" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLN1: 1.26-fold Down; FDR = 0.0101; PValue = 0.00238; mean CPM = 1820; talin 1" ID="ID_755848739" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FYN: 1.22-fold Up; FDR = 0.0156; PValue = 0.00393; mean CPM = 92.94; FYN oncogene related to SRC, FGR, YES" ID="ID_956634472" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_1145709305" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB1: 1.23-fold Up; FDR = 0.0759; PValue = 0.0253; mean CPM = 2700; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)" ID="ID_1429748111" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMA4: 1.2-fold Down; FDR = 0.0793; PValue = 0.0266; mean CPM = 624.4; laminin, alpha 4" ID="ID_1044292303" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_342265356" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_1897367521" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014969: 1.93-fold Down; FDR = 0.303; PValue = 0.137; mean CPM = 0.9384; Uncharacterized protein" ID="ID_1893450395" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB3: 1.6-fold Down; FDR = 0.303; PValue = 0.137; mean CPM = 1.445; laminin, beta 3" ID="ID_172152127" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRKL: 1.11-fold Up; FDR = 0.371; PValue = 0.176; mean CPM = 34.10; v-crk sarcoma virus CT10 oncogene homolog (avian)-like" ID="ID_217929253" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2: 1.1-fold Up; FDR = 0.394; PValue = 0.191; mean CPM = 102.5; PTK2 protein tyrosine kinase 2" ID="ID_1691458347" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA1: 1.1-fold Down; FDR = 0.57; PValue = 0.308; mean CPM = 422.3; integrin, alpha 1" ID="ID_899699638" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSK: 1.06-fold Down; FDR = 0.673; PValue = 0.386; mean CPM = 45.36; c-src tyrosine kinase" ID="ID_1748506563" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCR: 1.2-fold Down; FDR = 0.687; PValue = 0.397; mean CPM = 1.982; breakpoint cluster region" ID="ID_415976344" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014966: 1.43-fold Down; FDR = 0.72; PValue = 0.423; mean CPM = 0.9009; Uncharacterized protein" ID="ID_1231004864" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MLC1: 1.36-fold Down; FDR = 0.74; PValue = 0.442; mean CPM = 0.9395; megalencephalic leukoencephalopathy with subcortical cysts 1" ID="ID_690397918" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAPGEF1: 1.05-fold Down; FDR = 0.763; PValue = 0.462; mean CPM = 70.38; Rap guanine nucleotide exchange factor (GEF) 1" ID="ID_1954068801" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/biocarta induction of apoptosis through dr3 and dr4/5 death receptors: Activated, FDR = 0.115, FWER = 0.346, PValue = 0.00202" ID="ID_1069459267" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_535454174" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF10: 44.5-fold Up; FDR = 2.83e-16; PValue = 2.4e-18; mean CPM = 6.029; Tumor necrosis factor ligand superfamily member 10 isoform 1; Uncharacterized protein" ID="ID_1273835566" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BID: 1.66-fold Up; FDR = 5.41e-09; PValue = 2.19e-10; mean CPM = 35.19; BH3 interacting domain death agonist" ID="ID_237572307" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_604869674" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_278914749" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LMNA: 1.49-fold Down; FDR = 4.66e-05; PValue = 5.23e-06; mean CPM = 1329; lamin A/C" ID="ID_1576274872" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACTA1: 5.36-fold Down; FDR = 0.000251; PValue = 3.52e-05; mean CPM = 5.880; Uncharacterized protein" ID="ID_511563330" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PARP1: 1.46-fold Down; FDR = 0.00173; PValue = 0.000315; mean CPM = 46.95; poly (ADP-ribose) polymerase 1" ID="ID_616873506" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K14: 1.47-fold Down; FDR = 0.00704; PValue = 0.00157; mean CPM = 9.470; mitogen-activated protein kinase kinase kinase 14" ID="ID_388214983" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP10: 1.81-fold Up; FDR = 0.0175; PValue = 0.0045; mean CPM = 2.876; caspase 10, apoptosis-related cysteine peptidase" ID="ID_790402310" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRADD: 1.22-fold Up; FDR = 0.0319; PValue = 0.00907; mean CPM = 34.75; TNFRSF1A-associated via death domain" ID="ID_344056048" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FADD: 1.18-fold Down; FDR = 0.0936; PValue = 0.0324; mean CPM = 30.89; Uncharacterized protein" ID="ID_828660144" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP6: 1.17-fold Up; FDR = 0.197; PValue = 0.0807; mean CPM = 14.25; caspase 6, apoptosis-related cysteine peptidase" ID="ID_209253429" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP7: 1.15-fold Up; FDR = 0.218; PValue = 0.0916; mean CPM = 21.49; caspase 7, apoptosis-related cysteine peptidase" ID="ID_1857749655" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_1307026013" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF25: 1.2-fold Up; FDR = 0.772; PValue = 0.471; mean CPM = 1.687; tumor necrosis factor receptor superfamily, member 25" ID="ID_410288157" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GAS2: 1.4-fold Up; FDR = 0.826; PValue = 0.526; mean CPM = 0.7983; growth arrest-specific 2" ID="ID_465368699" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPTAN1: 1.01-fold Up; FDR = 1; PValue = 0.881; mean CPM = 946.2; spectrin, alpha, non-erythrocytic 1" ID="ID_1202274247" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/biocarta overview of telomerase protein component gene htert transcriptional regulation: Activated, FDR = 0.338, FWER = 1, PValue = 0.00963" ID="ID_528142977" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="ESR1: 5.04-fold Up; FDR = 6.62e-08; PValue = 3.55e-09; mean CPM = 2.845; estrogen receptor 1" ID="ID_611390009" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAX: 1.28-fold Up; FDR = 0.00569; PValue = 0.00123; mean CPM = 29.78; MYC associated factor X" ID="ID_944219439" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MXD1: 1.55-fold Down; FDR = 0.0118; PValue = 0.00285; mean CPM = 5.750; MAX dimerization protein 1" ID="ID_774076872" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SP1: 1.23-fold Up; FDR = 0.0139; PValue = 0.00344; mean CPM = 75.49; Transcription factor Sp1 isoform a; Uncharacterized protein" ID="ID_998478800" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC1: 1.25-fold Up; FDR = 0.0159; PValue = 0.00403; mean CPM = 27.51; histone deacetylase 1" ID="ID_1141797265" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MZF1: 1.33-fold Down; FDR = 0.0304; PValue = 0.00854; mean CPM = 8.648; myeloid zinc finger 1" ID="ID_787433645" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_1707434157" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WT1: 1.79-fold Down; FDR = 0.0975; PValue = 0.034; mean CPM = 1.442; Wilms tumor 1" ID="ID_685902907" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP53: 1.11-fold Down; FDR = 0.364; PValue = 0.172; mean CPM = 33.25; tumor protein p53" ID="ID_761600699" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TERT: 1.35-fold Down; FDR = 0.909; PValue = 0.691; mean CPM = 0.8377; telomerase reverse transcriptase" ID="ID_1838684346" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/biocarta skeletal muscle hypertrophy is regulated via akt-mtor pathway: Inhibited, FDR = 0.338, FWER = 1, PValue = 0.0115" ID="ID_1087695205" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="EIF2S2: 1.82-fold Up; FDR = 1.95e-08; PValue = 9.11e-10; mean CPM = 302.8; eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa" ID="ID_217620210" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_680140306" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1: 5.76-fold Down; FDR = 6.73e-06; PValue = 6.04e-07; mean CPM = 1.536; insulin-like growth factor 1 (somatomedin C)" ID="ID_956870758" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF4G1: 1.44-fold Down; FDR = 9.7e-06; PValue = 9.1e-07; mean CPM = 656.9; eukaryotic translation initiation factor 4 gamma, 1" ID="ID_627680377" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1R: 1.51-fold Down; FDR = 1.02e-05; PValue = 9.61e-07; mean CPM = 213.2; insulin-like growth factor 1 receptor" ID="ID_1829808127" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2S1: 1.42-fold Up; FDR = 5.59e-05; PValue = 6.42e-06; mean CPM = 79.87; eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa" ID="ID_1671149654" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTOR: 1.3-fold Down; FDR = 0.00117; PValue = 0.000201; mean CPM = 107.5; mechanistic target of rapamycin (serine/threonine kinase)" ID="ID_875849227" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R5D: 1.27-fold Down; FDR = 0.00482; PValue = 0.00101; mean CPM = 35.61; protein phosphatase 2, regulatory subunit B', delta" ID="ID_1358607811" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF4A1: 1.26-fold Up; FDR = 0.0102; PValue = 0.00241; mean CPM = 1010; eukaryotic translation initiation factor 4A1 pseudogene 4" ID="ID_1362190510" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_553582691" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDPK1: 1.24-fold Down; FDR = 0.0361; PValue = 0.0105; mean CPM = 17.53; 3-phosphoinositide dependent protein kinase-1" ID="ID_637795621" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INPPL1: 1.2-fold Down; FDR = 0.0395; PValue = 0.0117; mean CPM = 129.4; Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2; Uncharacterized protein" ID="ID_287733250" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MKNK1: 1.27-fold Down; FDR = 0.0706; PValue = 0.0232; mean CPM = 9.169; MAP kinase interacting serine/threonine kinase 1" ID="ID_953090016" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF4EBP1: 1.23-fold Up; FDR = 0.0729; PValue = 0.0241; mean CPM = 40.55; eukaryotic translation initiation factor 4E binding protein 1" ID="ID_1189168934" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_1726263390" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PABPC1: 1.1-fold Up; FDR = 0.489; PValue = 0.251; mean CPM = 25.34; Polyadenylate-binding protein 1; Uncharacterized protein" ID="ID_1614985436" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6: 1.08-fold Up; FDR = 0.584; PValue = 0.318; mean CPM = 892.5; ribosomal protein S6" ID="ID_1930986812" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB1: 1.04-fold Up; FDR = 0.88; PValue = 0.6; mean CPM = 30.80; Uncharacterized protein" ID="ID_516629307" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2B5: 1.01-fold Up; FDR = 1; PValue = 0.864; mean CPM = 62.81; eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa" ID="ID_750548415" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PABPC1: No Change; FDR = 1; PValue = 0.973; mean CPM = 5.391; poly(A) binding protein, cytoplasmic 1" ID="ID_715806860" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2S3: No Change; FDR = 1; PValue = 0.993; mean CPM = 74.68; eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa" ID="ID_40822094" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000005391: No Change; FDR = 1; PValue = 1; mean CPM = 0.7800; Uncharacterized protein" ID="ID_1893291739" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000009159: No Change; FDR = 1; PValue = 1; mean CPM = 0.7802; Uncharacterized protein" ID="ID_333805652" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/biocarta the igf-1 receptor and longevity: Inhibited, FDR = 0.338, FWER = 1, PValue = 0.0118" ID="ID_311752749" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CAT: 1.75-fold Up; FDR = 1.21e-09; PValue = 4.14e-11; mean CPM = 42.72; catalase" ID="ID_1670970817" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_1517508929" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRS1: 2.78-fold Up; FDR = 7.67e-09; PValue = 3.19e-10; mean CPM = 26.55; Uncharacterized protein" ID="ID_1082344652" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_14029912" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1: 5.76-fold Down; FDR = 6.73e-06; PValue = 6.04e-07; mean CPM = 1.536; insulin-like growth factor 1 (somatomedin C)" ID="ID_815249302" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1R: 1.51-fold Down; FDR = 1.02e-05; PValue = 9.61e-07; mean CPM = 213.2; insulin-like growth factor 1 receptor" ID="ID_1412503532" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1773276989" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDPK1: 1.24-fold Down; FDR = 0.0361; PValue = 0.0105; mean CPM = 17.53; 3-phosphoinositide dependent protein kinase-1" ID="ID_658163246" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_1056307955" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1224543248" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_1018431773" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/biocarta proteasome complex: Inhibited, FDR = 0.344, FWER = 1, PValue = 0.0141" ID="ID_1172547933" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="PSMA6: 3.39-fold Up; FDR = 3.27e-19; PValue = 1.49e-21; mean CPM = 174.6; proteasome (prosome, macropain) subunit, alpha type, 6" ID="ID_144608380" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMA4: 2.69-fold Up; FDR = 1.03e-16; PValue = 8.26e-19; mean CPM = 125.7; proteasome (prosome, macropain) subunit, alpha type, 4" ID="ID_494870236" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMA2: 1.94-fold Up; FDR = 8.77e-14; PValue = 1.15e-15; mean CPM = 126.0; proteasome (prosome, macropain) subunit, alpha type, 2" ID="ID_1310961244" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMA3: 1.97-fold Up; FDR = 2.59e-12; PValue = 4.66e-14; mean CPM = 94.63; proteasome (prosome, macropain) subunit, alpha type, 3" ID="ID_841197086" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMA5: 1.71-fold Up; FDR = 2.64e-10; PValue = 7.81e-12; mean CPM = 103.0; proteasome (prosome, macropain) subunit, alpha type, 5" ID="ID_639394212" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMA1: 1.56-fold Up; FDR = 9.63e-09; PValue = 4.15e-10; mean CPM = 100.6; proteasome (prosome, macropain) subunit, alpha type, 1" ID="ID_1909714333" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMB1: 1.54-fold Up; FDR = 3.38e-08; PValue = 1.68e-09; mean CPM = 193.0; proteasome (prosome, macropain) subunit, beta type, 1" ID="ID_306984506" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMD14: 1.38-fold Up; FDR = 5.19e-05; PValue = 5.91e-06; mean CPM = 63.67; proteasome (prosome, macropain) 26S subunit, non-ATPase, 14" ID="ID_1292389187" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMB7: 1.32-fold Up; FDR = 0.000758; PValue = 0.000123; mean CPM = 186.3; proteasome (prosome, macropain) subunit, beta type, 7" ID="ID_227013958" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMA7: 1.3-fold Up; FDR = 0.00111; PValue = 0.00019; mean CPM = 83.97; proteasome (prosome, macropain) subunit, alpha type, 7" ID="ID_1517689230" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMB2: 1.26-fold Up; FDR = 0.00539; PValue = 0.00116; mean CPM = 75.44; Proteasome subunit beta type" ID="ID_357652057" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMB4: 1.25-fold Up; FDR = 0.00737; PValue = 0.00165; mean CPM = 203.7; proteasome (prosome, macropain) subunit, beta type, 4" ID="ID_122427357" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPN2: 1.24-fold Down; FDR = 0.0118; PValue = 0.00285; mean CPM = 392.4; ribophorin II" ID="ID_1143843184" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPN1: 1.2-fold Down; FDR = 0.0443; PValue = 0.0133; mean CPM = 385.0; ribophorin I" ID="ID_254211196" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMD3: 1.17-fold Down; FDR = 0.0862; PValue = 0.0293; mean CPM = 144.8; proteasome (prosome, macropain) 26S subunit, non-ATPase, 3" ID="ID_1537974577" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="UBE2A: 1.21-fold Up; FDR = 0.0953; PValue = 0.0331; mean CPM = 15.80; Uncharacterized protein" ID="ID_1088442875" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="UBE3A: 1.2-fold Down; FDR = 0.117; PValue = 0.0423; mean CPM = 14.75; Ubiquitin-protein ligase E3A isoform 3; Uncharacterized protein" ID="ID_1332736383" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMB6: 1.15-fold Up; FDR = 0.129; PValue = 0.0478; mean CPM = 142.5; Proteasome subunit beta type" ID="ID_704349586" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMB3: 1.14-fold Up; FDR = 0.173; PValue = 0.0685; mean CPM = 101.4; proteasome (prosome, macropain) subunit, beta type, 3" ID="ID_751419366" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="UBE3A: 1.12-fold Down; FDR = 0.245; PValue = 0.105; mean CPM = 67.15; ubiquitin protein ligase E3A" ID="ID_229467479" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMD12: 1.12-fold Up; FDR = 0.262; PValue = 0.115; mean CPM = 79.63; proteasome (prosome, macropain) 26S subunit, non-ATPase, 12" ID="ID_1579112005" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMD11: 1.08-fold Up; FDR = 0.501; PValue = 0.259; mean CPM = 87.50; proteasome (prosome, macropain) 26S subunit, non-ATPase, 11" ID="ID_407636800" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMB5: 1.07-fold Down; FDR = 0.575; PValue = 0.312; mean CPM = 166.1; proteasome (prosome, macropain) subunit, beta type, 5" ID="ID_269732738" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000029957: 1.36-fold Down; FDR = 0.65; PValue = 0.368; mean CPM = 1.099; Uncharacterized protein" ID="ID_1846956758" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/biocarta human cytomegalovirus and map kinase pathways: Activated, FDR = 0.4, FWER = 1, PValue = 0.0187" ID="ID_1554413879" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_607698900" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RB1: 1.65-fold Up; FDR = 6.01e-08; PValue = 3.2e-09; mean CPM = 59.24; retinoblastoma 1" ID="ID_1423230563" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_50566288" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K3: 1.45-fold Down; FDR = 7.01e-06; PValue = 6.34e-07; mean CPM = 180.1; mitogen-activated protein kinase kinase 3" ID="ID_1013580260" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_690376397" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_98878468" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SP1: 1.23-fold Up; FDR = 0.0139; PValue = 0.00344; mean CPM = 75.49; Transcription factor Sp1 isoform a; Uncharacterized protein" ID="ID_831942668" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_992908305" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1995804397" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB1: 1.21-fold Up; FDR = 0.0313; PValue = 0.00884; mean CPM = 36.07; cAMP responsive element binding protein 1" ID="ID_1699753445" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDPK1: 1.24-fold Down; FDR = 0.0361; PValue = 0.0105; mean CPM = 17.53; 3-phosphoinositide dependent protein kinase-1" ID="ID_1325935222" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_87503306" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1741739213" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1466507276" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/biocarta b cell survival pathway: Inhibited, FDR = 0.4, FWER = 1, PValue = 0.0224" ID="ID_297151717" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="LAMC1: 2.28-fold Down; FDR = 6.46e-13; PValue = 1.01e-14; mean CPM = 812.1; laminin, gamma 1 (formerly LAMB2)" ID="ID_1437982514" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016591: 4.2-fold Down; FDR = 1.3e-11; PValue = 2.78e-13; mean CPM = 34.90; Uncharacterized protein" ID="ID_1832868485" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016587: 4.92-fold Down; FDR = 1.6e-11; PValue = 3.5e-13; mean CPM = 51.70; Uncharacterized protein" ID="ID_216361118" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_915108218" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1579400534" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMC2: 2.28-fold Down; FDR = 9.83e-06; PValue = 9.24e-07; mean CPM = 16.99; laminin, gamma 2" ID="ID_426991153" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB2: 1.48-fold Down; FDR = 0.000398; PValue = 5.93e-05; mean CPM = 695.6; laminin, beta 2 (laminin S)" ID="ID_1263082497" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTOR: 1.3-fold Down; FDR = 0.00117; PValue = 0.000201; mean CPM = 107.5; mechanistic target of rapamycin (serine/threonine kinase)" ID="ID_1983786586" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_579190420" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDPK1: 1.24-fold Down; FDR = 0.0361; PValue = 0.0105; mean CPM = 17.53; 3-phosphoinositide dependent protein kinase-1" ID="ID_295989003" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB1: 1.23-fold Up; FDR = 0.0759; PValue = 0.0253; mean CPM = 2700; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)" ID="ID_893021490" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMA4: 1.2-fold Down; FDR = 0.0793; PValue = 0.0266; mean CPM = 624.4; laminin, alpha 4" ID="ID_239901094" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DPF2: 1.16-fold Down; FDR = 0.114; PValue = 0.0409; mean CPM = 49.07; D4, zinc and double PHD fingers family 2" ID="ID_1030980981" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC5: 1.51-fold Down; FDR = 0.134; PValue = 0.0501; mean CPM = 18.55; Baculoviral IAP repeat-containing protein 5 isoform 1; Uncharacterized protein" ID="ID_1230895279" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP7: 1.15-fold Up; FDR = 0.218; PValue = 0.0916; mean CPM = 21.49; caspase 7, apoptosis-related cysteine peptidase" ID="ID_281620218" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014969: 1.93-fold Down; FDR = 0.303; PValue = 0.137; mean CPM = 0.9384; Uncharacterized protein" ID="ID_1956026200" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB3: 1.6-fold Down; FDR = 0.303; PValue = 0.137; mean CPM = 1.445; laminin, beta 3" ID="ID_1515211273" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA1: 1.1-fold Down; FDR = 0.57; PValue = 0.308; mean CPM = 422.3; integrin, alpha 1" ID="ID_50072109" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014966: 1.43-fold Down; FDR = 0.72; PValue = 0.423; mean CPM = 0.9009; Uncharacterized protein" ID="ID_912052457" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_846897136" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/biocarta mtor signaling pathway: Inhibited, FDR = 0.4, FWER = 1, PValue = 0.024" ID="ID_936847515" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="IRS1: 2.78-fold Up; FDR = 7.67e-09; PValue = 3.19e-10; mean CPM = 26.55; Uncharacterized protein" ID="ID_1674496823" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1742704338" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF3A: 1.42-fold Down; FDR = 7.09e-06; PValue = 6.42e-07; mean CPM = 85.49; eukaryotic translation initiation factor 3, subunit A" ID="ID_587710492" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF4G1: 1.44-fold Down; FDR = 9.7e-06; PValue = 9.1e-07; mean CPM = 656.9; eukaryotic translation initiation factor 4 gamma, 1" ID="ID_735033615" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TSC2: 1.44-fold Down; FDR = 1e-05; PValue = 9.42e-07; mean CPM = 124.0; tuberous sclerosis 2" ID="ID_1381563616" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTOR: 1.3-fold Down; FDR = 0.00117; PValue = 0.000201; mean CPM = 107.5; mechanistic target of rapamycin (serine/threonine kinase)" ID="ID_276454402" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R5D: 1.27-fold Down; FDR = 0.00482; PValue = 0.00101; mean CPM = 35.61; protein phosphatase 2, regulatory subunit B', delta" ID="ID_426223875" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF4A1: 1.26-fold Up; FDR = 0.0102; PValue = 0.00241; mean CPM = 1010; eukaryotic translation initiation factor 4A1 pseudogene 4" ID="ID_3378165" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1726943117" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDPK1: 1.24-fold Down; FDR = 0.0361; PValue = 0.0105; mean CPM = 17.53; 3-phosphoinositide dependent protein kinase-1" ID="ID_855323736" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TSC1: 1.19-fold Down; FDR = 0.0564; PValue = 0.0177; mean CPM = 38.34; tuberous sclerosis 1" ID="ID_49393400" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MKNK1: 1.27-fold Down; FDR = 0.0706; PValue = 0.0232; mean CPM = 9.169; MAP kinase interacting serine/threonine kinase 1" ID="ID_1746912195" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF4EBP1: 1.23-fold Up; FDR = 0.0729; PValue = 0.0241; mean CPM = 40.55; eukaryotic translation initiation factor 4E binding protein 1" ID="ID_1817220627" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHEB: 1.13-fold Up; FDR = 0.193; PValue = 0.0785; mean CPM = 118.9; Ras homolog enriched in brain" ID="ID_997429546" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GHR: 1.23-fold Up; FDR = 0.369; PValue = 0.175; mean CPM = 6.312; growth hormone receptor" ID="ID_470776514" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6: 1.08-fold Up; FDR = 0.584; PValue = 0.318; mean CPM = 892.5; ribosomal protein S6" ID="ID_132666944" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FKBP1A: 1.04-fold Down; FDR = 0.851; PValue = 0.562; mean CPM = 209.1; Peptidyl-prolyl cis-trans isomerase" ID="ID_1968853370" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB1: 1.04-fold Up; FDR = 0.88; PValue = 0.6; mean CPM = 30.80; Uncharacterized protein" ID="ID_681963652" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/biocarta ucalpain and friends in cell spread: Inhibited, FDR = 0.4, FWER = 1, PValue = 0.0257" ID="ID_253180453" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="LAMC1: 2.28-fold Down; FDR = 6.46e-13; PValue = 1.01e-14; mean CPM = 812.1; laminin, gamma 1 (formerly LAMB2)" ID="ID_633359392" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016591: 4.2-fold Down; FDR = 1.3e-11; PValue = 2.78e-13; mean CPM = 34.90; Uncharacterized protein" ID="ID_421895245" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016587: 4.92-fold Down; FDR = 1.6e-11; PValue = 3.5e-13; mean CPM = 51.70; Uncharacterized protein" ID="ID_453510426" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMC2: 2.28-fold Down; FDR = 9.83e-06; PValue = 9.24e-07; mean CPM = 16.99; laminin, gamma 2" ID="ID_340520922" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAPNS1: 1.4-fold Down; FDR = 6.09e-05; PValue = 7.11e-06; mean CPM = 239.1; calpain, small subunit 1" ID="ID_828937581" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACTA1: 5.36-fold Down; FDR = 0.000251; PValue = 3.52e-05; mean CPM = 5.880; Uncharacterized protein" ID="ID_1650265389" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB2: 1.48-fold Down; FDR = 0.000398; PValue = 5.93e-05; mean CPM = 695.6; laminin, beta 2 (laminin S)" ID="ID_1263142667" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EZR: 1.32-fold Up; FDR = 0.00112; PValue = 0.000192; mean CPM = 426.3; Uncharacterized protein" ID="ID_1883542034" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHOA: 1.28-fold Down; FDR = 0.00295; PValue = 0.000575; mean CPM = 277.8; ras homolog gene family, member A" ID="ID_836543283" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLN1: 1.26-fold Down; FDR = 0.0101; PValue = 0.00238; mean CPM = 1820; talin 1" ID="ID_1588826592" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB1: 1.23-fold Up; FDR = 0.0759; PValue = 0.0253; mean CPM = 2700; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)" ID="ID_833948753" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMA4: 1.2-fold Down; FDR = 0.0793; PValue = 0.0266; mean CPM = 624.4; laminin, alpha 4" ID="ID_1561351805" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014969: 1.93-fold Down; FDR = 0.303; PValue = 0.137; mean CPM = 0.9384; Uncharacterized protein" ID="ID_1851837834" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB3: 1.6-fold Down; FDR = 0.303; PValue = 0.137; mean CPM = 1.445; laminin, beta 3" ID="ID_784968613" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2: 1.1-fold Up; FDR = 0.394; PValue = 0.191; mean CPM = 102.5; PTK2 protein tyrosine kinase 2" ID="ID_891944350" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA1: 1.1-fold Down; FDR = 0.57; PValue = 0.308; mean CPM = 422.3; integrin, alpha 1" ID="ID_1644398509" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014966: 1.43-fold Down; FDR = 0.72; PValue = 0.423; mean CPM = 0.9009; Uncharacterized protein" ID="ID_164814879" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_469228531" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPTAN1: 1.01-fold Up; FDR = 1; PValue = 0.881; mean CPM = 946.2; spectrin, alpha, non-erythrocytic 1" ID="ID_1829936157" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/biocarta pdgf signaling pathway: Activated, FDR = 0.442, FWER = 1, PValue = 0.0331" ID="ID_1039887437" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_476527632" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFRA: 2.76-fold Up; FDR = 3.93e-14; PValue = 4.67e-16; mean CPM = 492.9; platelet-derived growth factor receptor, alpha polypeptide" ID="ID_775170157" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_1123190590" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SRF: 1.69-fold Down; FDR = 8.07e-11; PValue = 2.06e-12; mean CPM = 34.61; serum response factor (c-fos serum response element-binding transcription factor)" ID="ID_612908018" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_546737544" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFA: 1.92-fold Down; FDR = 2.56e-07; PValue = 1.58e-08; mean CPM = 22.99; platelet-derived growth factor alpha polypeptide" ID="ID_1313276201" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_289753364" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1351968681" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1696472250" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_1820913954" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG1: 1.31-fold Down; FDR = 0.00352; PValue = 0.000707; mean CPM = 53.66; phospholipase C, gamma 1" ID="ID_1250205351" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_513803527" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_458281956" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_1691039571" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_310758028" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1676139202" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_1851226469" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_193511457" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASA1: 1.03-fold Down; FDR = 0.909; PValue = 0.69; mean CPM = 103.7; Ras GTPase-activating protein 1 isoform 1; Uncharacterized protein" ID="ID_517364028" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_24280589" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_228550896" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/biocarta mets affect on macrophage differentiation: Activated, FDR = 0.442, FWER = 1, PValue = 0.0336" ID="ID_1278492794" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CSF1: 7.34-fold Up; FDR = 4.6e-20; PValue = 1.69e-22; mean CPM = 149.8; colony stimulating factor 1 (macrophage)" ID="ID_1014912338" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ETV3: 1.73-fold Down; FDR = 5.14e-07; PValue = 3.4e-08; mean CPM = 59.97; ets variant 3" ID="ID_1263791463" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSF1R: 1.92-fold Down; FDR = 0.00308; PValue = 0.000604; mean CPM = 3.242; colony stimulating factor 1 receptor" ID="ID_1708355573" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DDX20: 1.26-fold Up; FDR = 0.00895; PValue = 0.00207; mean CPM = 32.37; DEAD (Asp-Glu-Ala-Asp) box polypeptide 20" ID="ID_1016744296" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_1738881032" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="E2F1: 1.44-fold Down; FDR = 0.0425; PValue = 0.0127; mean CPM = 8.857; E2F transcription factor 1" ID="ID_896812835" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RBL1: 1.23-fold Up; FDR = 0.0472; PValue = 0.0144; mean CPM = 21.26; retinoblastoma-like 1 (p107)" ID="ID_1560725948" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_1103305545" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ETS1: 1.16-fold Up; FDR = 0.0996; PValue = 0.0348; mean CPM = 94.27; v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)" ID="ID_708540142" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_4864659" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RBL2: 1.09-fold Up; FDR = 0.445; PValue = 0.222; mean CPM = 47.90; retinoblastoma-like 2 (p130)" ID="ID_142413501" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ETS2: 1.04-fold Down; FDR = 0.92; PValue = 0.722; mean CPM = 25.97; v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)" ID="ID_1538687133" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="E2F4: 1.02-fold Down; FDR = 0.948; PValue = 0.771; mean CPM = 36.61; Transcription factor E2F4; Uncharacterized protein" ID="ID_1078004811" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/biocarta downregulated of mta-3 in er-negative breast tumors: Activated, FDR = 0.498, FWER = 1, PValue = 0.0408" ID="ID_88050824" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="ESR1: 5.04-fold Up; FDR = 6.62e-08; PValue = 3.55e-09; mean CPM = 2.845; estrogen receptor 1" ID="ID_1308780695" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTSD: 1.65-fold Down; FDR = 0.000162; PValue = 2.13e-05; mean CPM = 578.9; cathepsin D" ID="ID_1414736769" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC1: 1.25-fold Up; FDR = 0.0159; PValue = 0.00403; mean CPM = 27.51; histone deacetylase 1" ID="ID_247531494" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MBD3: 1.22-fold Down; FDR = 0.0194; PValue = 0.0051; mean CPM = 52.96; methyl-CpG binding domain protein 3" ID="ID_169556312" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDZK1: 1.51-fold Down; FDR = 0.0981; PValue = 0.0343; mean CPM = 2.469; PDZ domain containing 1" ID="ID_1484904683" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GREB1: 1.47-fold Down; FDR = 0.476; PValue = 0.242; mean CPM = 1.135; Uncharacterized protein" ID="ID_1139457157" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GAPDH: 1.01-fold Up; FDR = 1; PValue = 0.881; mean CPM = 4027; glyceraldehyde-3-phosphate dehydrogenase" ID="ID_771302000" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ALDOA: 1.01-fold Down; FDR = 1; PValue = 0.888; mean CPM = 2126; aldolase A, fructose-bisphosphate" ID="ID_1946449154" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/biocarta egf signaling pathway: Activated, FDR = 0.535, FWER = 1, PValue = 0.0476" ID="ID_499307480" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_272508060" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_1642519953" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_463096680" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGFR: 1.84-fold Up; FDR = 6.71e-09; PValue = 2.77e-10; mean CPM = 68.58; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)" ID="ID_1598801934" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1462826028" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_574773901" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1616233146" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_1147588241" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG1: 1.31-fold Down; FDR = 0.00352; PValue = 0.000707; mean CPM = 53.66; phospholipase C, gamma 1" ID="ID_69290310" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_587706771" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_1403552244" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_180039407" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_1135752098" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASA1: 1.03-fold Down; FDR = 0.909; PValue = 0.69; mean CPM = 103.7; Ras GTPase-activating protein 1 isoform 1; Uncharacterized protein" ID="ID_36183421" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_1784901071" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGF: 1.06-fold Down; FDR = 1; PValue = 0.885; mean CPM = 0.8917; epidermal growth factor" ID="ID_1064918941" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- </node>
- <node TEXT="kegg pathway collection" ID="ID_1857514429" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="graphite/kegg Focal adhesion: Inhibited, FDR = 3.42e-07, FWER = 3.42e-07, PValue = 2.36e-09" ID="ID_342085084" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="COL4A1: 7.03-fold Down; FDR = 1.47e-15; PValue = 1.34e-17; mean CPM = 3419; collagen, type IV, alpha 1" ID="ID_165257496" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL5A1: 4.69-fold Down; FDR = 3.09e-15; PValue = 2.99e-17; mean CPM = 1718; collagen, type V, alpha 1" ID="ID_1521896432" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL3A1: 20.5-fold Down; FDR = 5.71e-15; PValue = 5.82e-17; mean CPM = 5961; collagen, type III, alpha 1" ID="ID_392186983" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL11A1: 12.2-fold Down; FDR = 8.67e-15; PValue = 9.24e-17; mean CPM = 318.0; collagen, type XI, alpha 1" ID="ID_1777499325" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA5: 3.79-fold Down; FDR = 1.33e-14; PValue = 1.48e-16; mean CPM = 1237; integrin, alpha 5 (fibronectin receptor, alpha polypeptide)" ID="ID_580386521" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFRA: 2.76-fold Up; FDR = 3.93e-14; PValue = 4.67e-16; mean CPM = 492.9; platelet-derived growth factor receptor, alpha polypeptide" ID="ID_111363825" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL6A3: 4.93-fold Down; FDR = 5.63e-14; PValue = 6.87e-16; mean CPM = 1415; collagen, type VI, alpha 3" ID="ID_857236728" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL1A1: 21.5-fold Down; FDR = 1.13e-13; PValue = 1.5e-15; mean CPM = 15389; collagen, type I, alpha 1" ID="ID_794467801" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VEGFC: 2-fold Up; FDR = 1.3e-13; PValue = 1.76e-15; mean CPM = 238.4; Macaca mulatta vascular endothelial growth factor C (VEGFC), mRNA." ID="ID_246476145" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MET: 2.57-fold Up; FDR = 3.56e-13; PValue = 5.22e-15; mean CPM = 242.4; Macaca mulatta met proto-oncogene (hepatocyte growth factor receptor) (MET), mRNA." ID="ID_1839158296" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL1A2: 10.7-fold Down; FDR = 3.82e-13; PValue = 5.68e-15; mean CPM = 17923; collagen, type I, alpha 2" ID="ID_720677973" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VCL: 2.48-fold Down; FDR = 5.94e-13; PValue = 9.16e-15; mean CPM = 1013; vinculin" ID="ID_507715963" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMC1: 2.28-fold Down; FDR = 6.46e-13; PValue = 1.01e-14; mean CPM = 812.1; laminin, gamma 1 (formerly LAMB2)" ID="ID_1992603224" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC4: 7.09-fold Down; FDR = 1.82e-12; PValue = 3.1e-14; mean CPM = 6.421; SHC (Src homology 2 domain containing) family, member 4" ID="ID_1339112133" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016591: 4.2-fold Down; FDR = 1.3e-11; PValue = 2.78e-13; mean CPM = 34.90; Uncharacterized protein" ID="ID_265423611" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016587: 4.92-fold Down; FDR = 1.6e-11; PValue = 3.5e-13; mean CPM = 51.70; Uncharacterized protein" ID="ID_180686702" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAV: 2.64-fold Down; FDR = 6.04e-11; PValue = 1.51e-12; mean CPM = 337.3; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)" ID="ID_94485637" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND3: 2.27-fold Down; FDR = 8.38e-11; PValue = 2.15e-12; mean CPM = 86.90; cyclin D3" ID="ID_102681747" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC2: 1.96-fold Up; FDR = 1.01e-10; PValue = 2.62e-12; mean CPM = 53.58; baculoviral IAP repeat-containing 2" ID="ID_111081561" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL5A3: 5.21-fold Down; FDR = 1.78e-10; PValue = 4.98e-12; mean CPM = 79.70; collagen, type V, alpha 3" ID="ID_1733428625" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THBS2: 6.46-fold Down; FDR = 3.61e-10; PValue = 1.1e-11; mean CPM = 199.9; thrombospondin 2" ID="ID_588650149" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB8: 3.97-fold Up; FDR = 6.37e-10; PValue = 2.06e-11; mean CPM = 11.37; integrin, beta 8" ID="ID_596538807" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA2: 2.84-fold Up; FDR = 7.38e-10; PValue = 2.42e-11; mean CPM = 176.3; integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)" ID="ID_764770911" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB3: 5.02-fold Down; FDR = 1.72e-09; PValue = 6.17e-11; mean CPM = 43.21; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)" ID="ID_1450478857" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL5A2: 2.25-fold Down; FDR = 2.26e-09; PValue = 8.27e-11; mean CPM = 2999; collagen, type V, alpha 2" ID="ID_682272459" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_1248517588" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGFR: 1.84-fold Up; FDR = 6.71e-09; PValue = 2.77e-10; mean CPM = 68.58; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)" ID="ID_1139154360" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB5: 1.61-fold Down; FDR = 8.23e-09; PValue = 3.47e-10; mean CPM = 471.0; integrin, beta 5" ID="ID_591437560" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA10: 4.95-fold Down; FDR = 1.77e-08; PValue = 8.13e-10; mean CPM = 5.184; integrin, alpha 10" ID="ID_1378563470" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FLNA: 2.35-fold Down; FDR = 2.01e-08; PValue = 9.45e-10; mean CPM = 7159; filamin A, alpha" ID="ID_144383391" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYL9: 2.18-fold Down; FDR = 2.17e-08; PValue = 1.03e-09; mean CPM = 805.4; myosin, light chain 9, regulatory" ID="ID_348547583" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA8: 4.04-fold Down; FDR = 5.89e-08; PValue = 3.12e-09; mean CPM = 145.8; integrin, alpha 8" ID="ID_781432862" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ILK: 1.53-fold Down; FDR = 5.97e-08; PValue = 3.17e-09; mean CPM = 256.9; integrin-linked kinase" ID="ID_127576748" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACTN4: 1.63-fold Down; FDR = 6.46e-08; PValue = 3.46e-09; mean CPM = 631.8; actinin, alpha 4" ID="ID_1177308080" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THBS3: 1.97-fold Up; FDR = 7.19e-08; PValue = 3.88e-09; mean CPM = 128.6; thrombospondin 3" ID="ID_505835758" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COMP: 4.64-fold Down; FDR = 7.47e-08; PValue = 4.04e-09; mean CPM = 13.27; cartilage oligomeric matrix protein" ID="ID_1869728518" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1B: 1.55-fold Up; FDR = 2.39e-07; PValue = 1.46e-08; mean CPM = 135.3; Ras-related protein Rap-1b; Ras-related protein Rap-1b isoform 1; Uncharacterized protein" ID="ID_1820658183" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFA: 1.92-fold Down; FDR = 2.56e-07; PValue = 1.58e-08; mean CPM = 22.99; platelet-derived growth factor alpha polypeptide" ID="ID_877559178" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNC: 1.97-fold Down; FDR = 4.07e-07; PValue = 2.63e-08; mean CPM = 2667; tenascin C" ID="ID_1114123868" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1691502397" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYLK: 2.29-fold Down; FDR = 1.02e-06; PValue = 7.45e-08; mean CPM = 128.3; myosin light chain kinase" ID="ID_1186435525" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FLNB: 1.64-fold Down; FDR = 1.25e-06; PValue = 9.2e-08; mean CPM = 1975; filamin B, beta" ID="ID_674300794" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_357973993" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_776660099" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THBS1: 2.74-fold Down; FDR = 1.68e-06; PValue = 1.28e-07; mean CPM = 25785; thrombospondin 1" ID="ID_1296810135" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC3: 2.79-fold Up; FDR = 1.74e-06; PValue = 1.32e-07; mean CPM = 95.34; baculoviral IAP repeat-containing 3" ID="ID_1580699950" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1958483690" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC3: 1.68-fold Down; FDR = 2.72e-06; PValue = 2.19e-07; mean CPM = 13.98; ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)" ID="ID_236724363" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL4A5: 2.03-fold Down; FDR = 3.06e-06; PValue = 2.48e-07; mean CPM = 9.810; collagen, type IV, alpha 5" ID="ID_1037849277" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL6A1: 1.85-fold Down; FDR = 6.65e-06; PValue = 5.96e-07; mean CPM = 1937; collagen, type VI, alpha 1" ID="ID_1267827229" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1: 5.76-fold Down; FDR = 6.73e-06; PValue = 6.04e-07; mean CPM = 1.536; insulin-like growth factor 1 (somatomedin C)" ID="ID_1772564284" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FLNC: 1.74-fold Down; FDR = 7.81e-06; PValue = 7.15e-07; mean CPM = 868.2; filamin C, gamma" ID="ID_617182134" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMC2: 2.28-fold Down; FDR = 9.83e-06; PValue = 9.24e-07; mean CPM = 16.99; laminin, gamma 2" ID="ID_1307333414" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1R: 1.51-fold Down; FDR = 1.02e-05; PValue = 9.61e-07; mean CPM = 213.2; insulin-like growth factor 1 receptor" ID="ID_1114904491" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1541270479" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPP1: 2.25-fold Down; FDR = 7.74e-05; PValue = 9.29e-06; mean CPM = 35.33; secreted phosphoprotein 1" ID="ID_687566730" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARHGAP5: 1.36-fold Up; FDR = 0.000133; PValue = 1.7e-05; mean CPM = 130.2; Rho GTPase activating protein 5" ID="ID_1960418072" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCAR1: 1.36-fold Up; FDR = 0.000193; PValue = 2.61e-05; mean CPM = 210.4; breast cancer anti-estrogen resistance 1" ID="ID_1146490189" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYL5: 2.41-fold Up; FDR = 0.000248; PValue = 3.48e-05; mean CPM = 2.729; myosin, light chain 5, regulatory" ID="ID_888657991" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL6A2: 1.47-fold Down; FDR = 0.000287; PValue = 4.1e-05; mean CPM = 1544; collagen, type VI, alpha 2" ID="ID_844295860" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VEGFA: 1.47-fold Up; FDR = 0.000317; PValue = 4.59e-05; mean CPM = 463.7; vascular endothelial growth factor A" ID="ID_1562691917" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HGF: 1.85-fold Down; FDR = 0.000377; PValue = 5.58e-05; mean CPM = 137.4; hepatocyte growth factor (hepapoietin A; scatter factor)" ID="ID_1366733436" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB2: 1.48-fold Down; FDR = 0.000398; PValue = 5.93e-05; mean CPM = 695.6; laminin, beta 2 (laminin S)" ID="ID_1583522746" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA3: 1.34-fold Down; FDR = 0.000518; PValue = 7.96e-05; mean CPM = 126.8; integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)" ID="ID_798017193" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAD: 1.36-fold Down; FDR = 0.000605; PValue = 9.52e-05; mean CPM = 48.46; BCL2-associated agonist of cell death" ID="ID_622521457" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZYX: 1.29-fold Down; FDR = 0.00237; PValue = 0.00045; mean CPM = 287.5; Uncharacterized protein" ID="ID_1592785774" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK3: 3.55-fold Up; FDR = 0.00273; PValue = 0.000527; mean CPM = 1.136; p21 protein (Cdc42/Rac)-activated kinase 3" ID="ID_1928119035" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHOA: 1.28-fold Down; FDR = 0.00295; PValue = 0.000575; mean CPM = 277.8; ras homolog gene family, member A" ID="ID_1054214409" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1B: 1.43-fold Up; FDR = 0.00346; PValue = 0.000693; mean CPM = 12.81; RAP1B, member of RAS oncogene family" ID="ID_526967649" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB4: 1.66-fold Down; FDR = 0.00369; PValue = 0.000748; mean CPM = 5.291; integrin, beta 4" ID="ID_1235880563" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP1R12B: 1.52-fold Down; FDR = 0.00383; PValue = 0.000782; mean CPM = 15.41; protein phosphatase 1, regulatory (inhibitor) subunit 12B" ID="ID_404685994" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYL12B: 1.28-fold Up; FDR = 0.00408; PValue = 0.00084; mean CPM = 372.0; myosin, light chain 12B, regulatory" ID="ID_83729249" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV3: 1.82-fold Down; FDR = 0.00463; PValue = 0.000973; mean CPM = 7.044; vav 3 guanine nucleotide exchange factor" ID="ID_483949102" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIP5K1C: 1.27-fold Down; FDR = 0.00491; PValue = 0.00104; mean CPM = 37.75; phosphatidylinositol-4-phosphate 5-kinase, type I, gamma" ID="ID_499668426" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAV1: 1.33-fold Down; FDR = 0.00575; PValue = 0.00125; mean CPM = 228.7; caveolin-1" ID="ID_1756334859" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VASP: 1.26-fold Down; FDR = 0.00581; PValue = 0.00126; mean CPM = 250.9; vasodilator-stimulated phosphoprotein" ID="ID_916144539" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_1778062656" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARHGAP35: 1.25-fold Up; FDR = 0.00754; PValue = 0.0017; mean CPM = 176.9; Rho GTPase activating protein 35" ID="ID_762122527" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLN1: 1.26-fold Down; FDR = 0.0101; PValue = 0.00238; mean CPM = 1820; talin 1" ID="ID_1056002290" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYL12A: 1.25-fold Up; FDR = 0.0122; PValue = 0.00294; mean CPM = 576.5; myosin, light chain 12A, regulatory, non-sarcomeric" ID="ID_1711318275" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFB: 1.97-fold Down; FDR = 0.0133; PValue = 0.00326; mean CPM = 2.424; platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)" ID="ID_886615191" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FYN: 1.22-fold Up; FDR = 0.0156; PValue = 0.00393; mean CPM = 92.94; FYN oncogene related to SRC, FGR, YES" ID="ID_1859089573" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FN1: 1.7-fold Down; FDR = 0.0164; PValue = 0.00417; mean CPM = 40317; fibronectin 1" ID="ID_1613351899" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA2B: 1.71-fold Down; FDR = 0.0187; PValue = 0.00486; mean CPM = 2.655; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)" ID="ID_1793556982" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_438565165" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1318132684" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC2: 2.96-fold Up; FDR = 0.0309; PValue = 0.00872; mean CPM = 0.9737; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)" ID="ID_1568496918" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KDR: 2.01-fold Up; FDR = 0.0328; PValue = 0.00936; mean CPM = 2.053; kinase insert domain receptor (a type III receptor tyrosine kinase)" ID="ID_1256769065" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PARVA: 1.2-fold Down; FDR = 0.0352; PValue = 0.0102; mean CPM = 126.1; parvin, alpha" ID="ID_1029756536" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDPK1: 1.24-fold Down; FDR = 0.0361; PValue = 0.0105; mean CPM = 17.53; 3-phosphoinositide dependent protein kinase-1" ID="ID_327701919" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL2A1: 2.38-fold Down; FDR = 0.0368; PValue = 0.0107; mean CPM = 1.117; Uncharacterized protein" ID="ID_1950114847" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK6: 3.06-fold Down; FDR = 0.04; PValue = 0.0118; mean CPM = 0.9224; p21 protein (Cdc42/Rac)-activated kinase 6" ID="ID_1375205899" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTNNB1: 1.2-fold Up; FDR = 0.0498; PValue = 0.0153; mean CPM = 558.3; catenin (cadherin-associated protein), beta 1, 88kDa" ID="ID_947445950" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_1357243403" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK4: 1.21-fold Down; FDR = 0.0756; PValue = 0.0252; mean CPM = 16.78; p21 protein (Cdc42/Rac)-activated kinase 4" ID="ID_472869880" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB1: 1.23-fold Up; FDR = 0.0759; PValue = 0.0253; mean CPM = 2700; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)" ID="ID_1686324060" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMA4: 1.2-fold Down; FDR = 0.0793; PValue = 0.0266; mean CPM = 624.4; laminin, alpha 4" ID="ID_1947348211" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1A: 1.17-fold Up; FDR = 0.0888; PValue = 0.0304; mean CPM = 37.16; RAP1A, member of RAS oncogene family" ID="ID_1800523295" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS2: 1.17-fold Up; FDR = 0.1; PValue = 0.0353; mean CPM = 31.79; son of sevenless homolog 2 (Drosophila)" ID="ID_764051732" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND1: 1.17-fold Up; FDR = 0.121; PValue = 0.0443; mean CPM = 867.3; cyclin D1" ID="ID_1842349472" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_105128827" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IBSP: 2.51-fold Down; FDR = 0.128; PValue = 0.0476; mean CPM = 0.8896; integrin-binding sialoprotein" ID="ID_1606915424" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK2: 1.15-fold Up; FDR = 0.134; PValue = 0.0502; mean CPM = 89.49; p21 protein (Cdc42/Rac)-activated kinase 2" ID="ID_810077651" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_47898289" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1246445556" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTEN: 1.14-fold Up; FDR = 0.166; PValue = 0.065; mean CPM = 89.60; phosphatase and tensin homolog" ID="ID_1609512323" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ROCK2: 1.14-fold Up; FDR = 0.166; PValue = 0.065; mean CPM = 247.7; Rho-associated, coiled-coil containing protein kinase 2" ID="ID_583943892" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP1R12A: 1.14-fold Up; FDR = 0.167; PValue = 0.0655; mean CPM = 282.7; protein phosphatase 1, regulatory (inhibitor) subunit 12A" ID="ID_175972066" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VWF: 1.42-fold Down; FDR = 0.174; PValue = 0.069; mean CPM = 24.05; von Willebrand factor" ID="ID_106872831" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XIAP: 1.17-fold Up; FDR = 0.177; PValue = 0.0706; mean CPM = 19.21; X-linked inhibitor of apoptosis" ID="ID_1913553496" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC2: 1.34-fold Down; FDR = 0.191; PValue = 0.0774; mean CPM = 7.313; SHC (Src homology 2 domain containing) transforming protein 2" ID="ID_161414572" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_909074442" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PARVB: 1.14-fold Down; FDR = 0.199; PValue = 0.0817; mean CPM = 34.65; parvin, beta" ID="ID_1968804808" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_1676376984" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BRAF: 1.14-fold Down; FDR = 0.228; PValue = 0.0964; mean CPM = 24.98; v-raf murine sarcoma viral oncogene homolog B1" ID="ID_149415919" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ERBB2: 1.14-fold Down; FDR = 0.23; PValue = 0.0977; mean CPM = 119.0; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)" ID="ID_1296101730" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB4: 1.81-fold Down; FDR = 0.237; PValue = 0.101; mean CPM = 1.043; laminin, beta 4" ID="ID_1844120356" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAV2: 1.14-fold Down; FDR = 0.24; PValue = 0.103; mean CPM = 25.69; caveolin 2" ID="ID_689155643" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_780075138" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014969: 1.93-fold Down; FDR = 0.303; PValue = 0.137; mean CPM = 0.9384; Uncharacterized protein" ID="ID_1970468890" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB3: 1.6-fold Down; FDR = 0.303; PValue = 0.137; mean CPM = 1.445; laminin, beta 3" ID="ID_1463827186" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_1225579741" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND2: 1.2-fold Up; FDR = 0.335; PValue = 0.155; mean CPM = 76.91; cyclin D2" ID="ID_1289306294" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL6A6: 1.78-fold Down; FDR = 0.354; PValue = 0.166; mean CPM = 0.9461; collagen, type VI, alpha 6" ID="ID_510850788" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRKL: 1.11-fold Up; FDR = 0.371; PValue = 0.176; mean CPM = 34.10; v-crk sarcoma virus CT10 oncogene homolog (avian)-like" ID="ID_1816698769" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1854356628" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2: 1.48-fold Up; FDR = 0.384; PValue = 0.184; mean CPM = 1.344; Uncharacterized protein" ID="ID_1170643773" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2: 1.1-fold Up; FDR = 0.394; PValue = 0.191; mean CPM = 102.5; PTK2 protein tyrosine kinase 2" ID="ID_1043752951" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL4A3: 1.67-fold Down; FDR = 0.422; PValue = 0.207; mean CPM = 0.9315; collagen, type IV, alpha 3 (Goodpasture antigen)" ID="ID_468754778" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNN: 1.32-fold Up; FDR = 0.425; PValue = 0.209; mean CPM = 2.061; tenascin N" ID="ID_1109833069" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1488521390" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000026812: 1.61-fold Down; FDR = 0.46; PValue = 0.232; mean CPM = 0.9948; Uncharacterized protein" ID="ID_1002106421" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THBS4: 1.64-fold Down; FDR = 0.498; PValue = 0.257; mean CPM = 0.9543; thrombospondin 4" ID="ID_1226718669" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VEGFB: 1.1-fold Down; FDR = 0.512; PValue = 0.267; mean CPM = 16.03; vascular endothelial growth factor B" ID="ID_422439745" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_1144061445" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYLK2: 1.56-fold Down; FDR = 0.541; PValue = 0.288; mean CPM = 0.9259; myosin light chain kinase 2" ID="ID_902264717" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP1CB: 1.08-fold Up; FDR = 0.566; PValue = 0.306; mean CPM = 108.6; protein phosphatase 1, catalytic subunit, beta isozyme" ID="ID_1190550278" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA1: 1.1-fold Down; FDR = 0.57; PValue = 0.308; mean CPM = 422.3; integrin, alpha 1" ID="ID_792482293" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC3: 1.37-fold Down; FDR = 0.584; PValue = 0.318; mean CPM = 1.193; SHC-transforming protein 3; Uncharacterized protein" ID="ID_498545585" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA9: 1.3-fold Down; FDR = 0.595; PValue = 0.326; mean CPM = 1.685; integrin, alpha 9" ID="ID_1423686975" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDC42: 1.07-fold Down; FDR = 0.608; PValue = 0.335; mean CPM = 91.67; cell division cycle 42" ID="ID_332883326" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCG: 1.47-fold Down; FDR = 0.609; PValue = 0.336; mean CPM = 0.9297; protein kinase C, gamma" ID="ID_679517932" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL4A6: 1.4-fold Down; FDR = 0.631; PValue = 0.353; mean CPM = 1.078; collagen, type IV, alpha 6" ID="ID_1184744656" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VTN: 1.19-fold Up; FDR = 0.669; PValue = 0.382; mean CPM = 2.950; vitronectin" ID="ID_1870758287" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014966: 1.43-fold Down; FDR = 0.72; PValue = 0.423; mean CPM = 0.9009; Uncharacterized protein" ID="ID_1135699929" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA4: 1.16-fold Down; FDR = 0.722; PValue = 0.425; mean CPM = 5.425; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)" ID="ID_563564921" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCB: 1.86-fold Up; FDR = 0.727; PValue = 0.43; mean CPM = 0.8705; protein kinase C, beta" ID="ID_929891013" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB6: 1.4-fold Down; FDR = 0.732; PValue = 0.434; mean CPM = 0.9377; Integrin beta" ID="ID_1448439946" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAPGEF1: 1.05-fold Down; FDR = 0.763; PValue = 0.462; mean CPM = 70.38; Rap guanine nucleotide exchange factor (GEF) 1" ID="ID_1145406779" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRK: 1.05-fold Up; FDR = 0.791; PValue = 0.488; mean CPM = 59.92; v-crk sarcoma virus CT10 oncogene homolog (avian)" ID="ID_479705475" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACTN2: 1.69-fold Down; FDR = 0.791; PValue = 0.488; mean CPM = 0.8357; actinin, alpha 2" ID="ID_1610708071" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYLK4: 1.34-fold Up; FDR = 0.804; PValue = 0.5; mean CPM = 0.8719; Uncharacterized protein" ID="ID_1215187515" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DOCK1: 1.05-fold Up; FDR = 0.825; PValue = 0.524; mean CPM = 165.2; dedicator of cytokinesis 1" ID="ID_1718835592" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FLT1: 1.08-fold Down; FDR = 0.849; PValue = 0.558; mean CPM = 28.21; fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)" ID="ID_956419943" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV1: 1.25-fold Down; FDR = 0.858; PValue = 0.572; mean CPM = 0.9515; vav 1 guanine nucleotide exchange factor" ID="ID_231727356" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYLK3: 1.18-fold Up; FDR = 0.899; PValue = 0.629; mean CPM = 1.107; myosin light chain kinase 3" ID="ID_1714612065" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYL10: 1.36-fold Down; FDR = 0.903; PValue = 0.643; mean CPM = 0.8451; myosin, light chain 10, regulatory" ID="ID_1254628871" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASGRF1: 1.14-fold Down; FDR = 0.903; PValue = 0.648; mean CPM = 1.594; Ras protein-specific guanine nucleotide-releasing factor 1" ID="ID_1799504657" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FLT4: 1.19-fold Down; FDR = 0.909; PValue = 0.689; mean CPM = 0.8780; fms-related tyrosine kinase 4" ID="ID_1327703531" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYL2: 1.15-fold Up; FDR = 0.909; PValue = 0.69; mean CPM = 0.7911; myosin, light chain 2, regulatory, cardiac, slow" ID="ID_329624954" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK1: 1.03-fold Down; FDR = 0.911; PValue = 0.705; mean CPM = 18.65; p21 protein (Cdc42/Rac)-activated kinase 1" ID="ID_1722512986" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYLPF: 1.14-fold Down; FDR = 0.921; PValue = 0.723; mean CPM = 1.015; myosin light chain, phosphorylatable, fast skeletal muscle" ID="ID_104422997" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_1755089793" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_1429194488" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PARVG: 1.07-fold Down; FDR = 0.988; PValue = 0.839; mean CPM = 0.8784; parvin, gamma" ID="ID_172025556" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL11A2: 1.03-fold Down; FDR = 1; PValue = 0.872; mean CPM = 2.131; collagen, type XI, alpha 2" ID="ID_375036689" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFRB: 1.01-fold Up; FDR = 1; PValue = 0.883; mean CPM = 391.1; platelet-derived growth factor receptor, beta polypeptide" ID="ID_189586015" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGF: 1.06-fold Down; FDR = 1; PValue = 0.885; mean CPM = 0.8917; epidermal growth factor" ID="ID_1226661144" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL24A1: 1.04-fold Up; FDR = 1; PValue = 0.898; mean CPM = 1.201; collagen, type XXIV, alpha 1" ID="ID_1760005122" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNXB: 1.03-fold Up; FDR = 1; PValue = 0.909; mean CPM = 1.078; tenascin XB" ID="ID_1692136757" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK7: 1.01-fold Up; FDR = 1; PValue = 0.923; mean CPM = 0.8495; p21 protein (Cdc42/Rac)-activated kinase 7" ID="ID_1806144279" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB7: 1.01-fold Down; FDR = 1; PValue = 0.968; mean CPM = 2.025; integrin, beta 7" ID="ID_521855945" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV2: No Change; FDR = 1; PValue = 0.976; mean CPM = 25.65; vav 2 guanine nucleotide exchange factor" ID="ID_569437138" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAV3: 1.02-fold Down; FDR = 1; PValue = 0.98; mean CPM = 0.7970; caveolin 3" ID="ID_1189743155" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNR: 1.08-fold Down; FDR = 1; PValue = 0.984; mean CPM = 0.8556; tenascin R (restrictin, janusin)" ID="ID_450505837" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FIGF: 1.07-fold Up; FDR = 1; PValue = 0.995; mean CPM = 0.8037; c-fos induced growth factor (vascular endothelial growth factor D)" ID="ID_317118495" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg ECM-receptor interaction: Inhibited, FDR = 1.89e-06, FWER = 3.78e-06, PValue = 2.61e-08" ID="ID_542099224" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="COL4A1: 7.03-fold Down; FDR = 1.47e-15; PValue = 1.34e-17; mean CPM = 3419; collagen, type IV, alpha 1" ID="ID_88668161" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL5A1: 4.69-fold Down; FDR = 3.09e-15; PValue = 2.99e-17; mean CPM = 1718; collagen, type V, alpha 1" ID="ID_1668527740" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL3A1: 20.5-fold Down; FDR = 5.71e-15; PValue = 5.82e-17; mean CPM = 5961; collagen, type III, alpha 1" ID="ID_143647307" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD47: 2.13-fold Up; FDR = 6.33e-15; PValue = 6.54e-17; mean CPM = 59.15; CD47 molecule" ID="ID_1356779143" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL11A1: 12.2-fold Down; FDR = 8.67e-15; PValue = 9.24e-17; mean CPM = 318.0; collagen, type XI, alpha 1" ID="ID_897328636" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA5: 3.79-fold Down; FDR = 1.33e-14; PValue = 1.48e-16; mean CPM = 1237; integrin, alpha 5 (fibronectin receptor, alpha polypeptide)" ID="ID_897443150" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL6A3: 4.93-fold Down; FDR = 5.63e-14; PValue = 6.87e-16; mean CPM = 1415; collagen, type VI, alpha 3" ID="ID_1223356190" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL1A1: 21.5-fold Down; FDR = 1.13e-13; PValue = 1.5e-15; mean CPM = 15389; collagen, type I, alpha 1" ID="ID_1523350332" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL1A2: 10.7-fold Down; FDR = 3.82e-13; PValue = 5.68e-15; mean CPM = 17923; collagen, type I, alpha 2" ID="ID_1840411503" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMC1: 2.28-fold Down; FDR = 6.46e-13; PValue = 1.01e-14; mean CPM = 812.1; laminin, gamma 1 (formerly LAMB2)" ID="ID_961575800" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016591: 4.2-fold Down; FDR = 1.3e-11; PValue = 2.78e-13; mean CPM = 34.90; Uncharacterized protein" ID="ID_1382468723" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016587: 4.92-fold Down; FDR = 1.6e-11; PValue = 3.5e-13; mean CPM = 51.70; Uncharacterized protein" ID="ID_1094553554" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAV: 2.64-fold Down; FDR = 6.04e-11; PValue = 1.51e-12; mean CPM = 337.3; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)" ID="ID_1002563948" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL5A3: 5.21-fold Down; FDR = 1.78e-10; PValue = 4.98e-12; mean CPM = 79.70; collagen, type V, alpha 3" ID="ID_518515773" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THBS2: 6.46-fold Down; FDR = 3.61e-10; PValue = 1.1e-11; mean CPM = 199.9; thrombospondin 2" ID="ID_1078960939" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB8: 3.97-fold Up; FDR = 6.37e-10; PValue = 2.06e-11; mean CPM = 11.37; integrin, beta 8" ID="ID_11182064" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA2: 2.84-fold Up; FDR = 7.38e-10; PValue = 2.42e-11; mean CPM = 176.3; integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)" ID="ID_1263396915" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPG2: 2.83-fold Down; FDR = 8.45e-10; PValue = 2.83e-11; mean CPM = 1670; heparan sulfate proteoglycan 2" ID="ID_1855453778" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB3: 5.02-fold Down; FDR = 1.72e-09; PValue = 6.17e-11; mean CPM = 43.21; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)" ID="ID_1330529627" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL5A2: 2.25-fold Down; FDR = 2.26e-09; PValue = 8.27e-11; mean CPM = 2999; collagen, type V, alpha 2" ID="ID_746741531" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB5: 1.61-fold Down; FDR = 8.23e-09; PValue = 3.47e-10; mean CPM = 471.0; integrin, beta 5" ID="ID_1823679908" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA10: 4.95-fold Down; FDR = 1.77e-08; PValue = 8.13e-10; mean CPM = 5.184; integrin, alpha 10" ID="ID_1541647298" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA8: 4.04-fold Down; FDR = 5.89e-08; PValue = 3.12e-09; mean CPM = 145.8; integrin, alpha 8" ID="ID_888252845" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THBS3: 1.97-fold Up; FDR = 7.19e-08; PValue = 3.88e-09; mean CPM = 128.6; thrombospondin 3" ID="ID_508880958" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COMP: 4.64-fold Down; FDR = 7.47e-08; PValue = 4.04e-09; mean CPM = 13.27; cartilage oligomeric matrix protein" ID="ID_1129017714" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SDC4: 1.79-fold Up; FDR = 1.95e-07; PValue = 1.16e-08; mean CPM = 109.0; syndecan 4" ID="ID_1663340775" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNC: 1.97-fold Down; FDR = 4.07e-07; PValue = 2.63e-08; mean CPM = 2667; tenascin C" ID="ID_1276504804" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THBS1: 2.74-fold Down; FDR = 1.68e-06; PValue = 1.28e-07; mean CPM = 25785; thrombospondin 1" ID="ID_526297299" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL4A5: 2.03-fold Down; FDR = 3.06e-06; PValue = 2.48e-07; mean CPM = 9.810; collagen, type IV, alpha 5" ID="ID_1815438287" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SV2A: 5.8-fold Down; FDR = 3.38e-06; PValue = 2.79e-07; mean CPM = 1.583; synaptic vesicle glycoprotein 2A" ID="ID_995004950" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL6A1: 1.85-fold Down; FDR = 6.65e-06; PValue = 5.96e-07; mean CPM = 1937; collagen, type VI, alpha 1" ID="ID_1490412746" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMC2: 2.28-fold Down; FDR = 9.83e-06; PValue = 9.24e-07; mean CPM = 16.99; laminin, gamma 2" ID="ID_870559169" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SDC1: 2.19-fold Down; FDR = 2.55e-05; PValue = 2.66e-06; mean CPM = 12.60; syndecan 1" ID="ID_915434584" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPP1: 2.25-fold Down; FDR = 7.74e-05; PValue = 9.29e-06; mean CPM = 35.33; secreted phosphoprotein 1" ID="ID_716925186" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL6A2: 1.47-fold Down; FDR = 0.000287; PValue = 4.1e-05; mean CPM = 1544; collagen, type VI, alpha 2" ID="ID_854423092" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB2: 1.48-fold Down; FDR = 0.000398; PValue = 5.93e-05; mean CPM = 695.6; laminin, beta 2 (laminin S)" ID="ID_1772329781" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA3: 1.34-fold Down; FDR = 0.000518; PValue = 7.96e-05; mean CPM = 126.8; integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)" ID="ID_918601026" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB4: 1.66-fold Down; FDR = 0.00369; PValue = 0.000748; mean CPM = 5.291; integrin, beta 4" ID="ID_196152733" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GP1BA: 2.34-fold Down; FDR = 0.0114; PValue = 0.00273; mean CPM = 1.873; glycoprotein Ib (platelet), alpha polypeptide" ID="ID_546281710" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FN1: 1.7-fold Down; FDR = 0.0164; PValue = 0.00417; mean CPM = 40317; fibronectin 1" ID="ID_1131487111" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA2B: 1.71-fold Down; FDR = 0.0187; PValue = 0.00486; mean CPM = 2.655; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)" ID="ID_113733342" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL2A1: 2.38-fold Down; FDR = 0.0368; PValue = 0.0107; mean CPM = 1.117; Uncharacterized protein" ID="ID_5751199" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DAG1: 1.54-fold Down; FDR = 0.0661; PValue = 0.0214; mean CPM = 3.013; dystroglycan 1 (dystrophin-associated glycoprotein 1)" ID="ID_355826708" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB1: 1.23-fold Up; FDR = 0.0759; PValue = 0.0253; mean CPM = 2700; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)" ID="ID_1954420218" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMA4: 1.2-fold Down; FDR = 0.0793; PValue = 0.0266; mean CPM = 624.4; laminin, alpha 4" ID="ID_1176098885" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IBSP: 2.51-fold Down; FDR = 0.128; PValue = 0.0476; mean CPM = 0.8896; integrin-binding sialoprotein" ID="ID_98455461" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VWF: 1.42-fold Down; FDR = 0.174; PValue = 0.069; mean CPM = 24.05; von Willebrand factor" ID="ID_1212642854" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB4: 1.81-fold Down; FDR = 0.237; PValue = 0.101; mean CPM = 1.043; laminin, beta 4" ID="ID_214012335" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HMMR: 1.35-fold Down; FDR = 0.262; PValue = 0.114; mean CPM = 14.06; Uncharacterized protein" ID="ID_1141692969" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014969: 1.93-fold Down; FDR = 0.303; PValue = 0.137; mean CPM = 0.9384; Uncharacterized protein" ID="ID_772921346" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB3: 1.6-fold Down; FDR = 0.303; PValue = 0.137; mean CPM = 1.445; laminin, beta 3" ID="ID_371618294" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL6A6: 1.78-fold Down; FDR = 0.354; PValue = 0.166; mean CPM = 0.9461; collagen, type VI, alpha 6" ID="ID_613035866" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL4A3: 1.67-fold Down; FDR = 0.422; PValue = 0.207; mean CPM = 0.9315; collagen, type IV, alpha 3 (Goodpasture antigen)" ID="ID_1706934233" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNN: 1.32-fold Up; FDR = 0.425; PValue = 0.209; mean CPM = 2.061; tenascin N" ID="ID_567058692" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000026812: 1.61-fold Down; FDR = 0.46; PValue = 0.232; mean CPM = 0.9948; Uncharacterized protein" ID="ID_838979264" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THBS4: 1.64-fold Down; FDR = 0.498; PValue = 0.257; mean CPM = 0.9543; thrombospondin 4" ID="ID_935648773" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA1: 1.1-fold Down; FDR = 0.57; PValue = 0.308; mean CPM = 422.3; integrin, alpha 1" ID="ID_1494932820" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GP5: 1.22-fold Up; FDR = 0.577; PValue = 0.313; mean CPM = 2.454; glycoprotein V (platelet)" ID="ID_719797796" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA9: 1.3-fold Down; FDR = 0.595; PValue = 0.326; mean CPM = 1.685; integrin, alpha 9" ID="ID_1555319232" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL4A6: 1.4-fold Down; FDR = 0.631; PValue = 0.353; mean CPM = 1.078; collagen, type IV, alpha 6" ID="ID_332844794" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VTN: 1.19-fold Up; FDR = 0.669; PValue = 0.382; mean CPM = 2.950; vitronectin" ID="ID_1535901511" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014966: 1.43-fold Down; FDR = 0.72; PValue = 0.423; mean CPM = 0.9009; Uncharacterized protein" ID="ID_1549753716" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA4: 1.16-fold Down; FDR = 0.722; PValue = 0.425; mean CPM = 5.425; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)" ID="ID_649564094" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB6: 1.4-fold Down; FDR = 0.732; PValue = 0.434; mean CPM = 0.9377; Integrin beta" ID="ID_601044052" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GP9: 1.69-fold Up; FDR = 0.754; PValue = 0.454; mean CPM = 0.8166; glycoprotein IX (platelet)" ID="ID_978350816" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SV2B: 1.71-fold Up; FDR = 0.794; PValue = 0.49; mean CPM = 0.8302; synaptic vesicle glycoprotein 2B" ID="ID_1486891492" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AGRN: 1.07-fold Down; FDR = 0.828; PValue = 0.53; mean CPM = 103.0; agrin" ID="ID_275777599" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD36: 1.23-fold Up; FDR = 0.84; PValue = 0.547; mean CPM = 1.074; CD36 molecule (thrombospondin receptor)" ID="ID_771018672" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GP6: 1.29-fold Up; FDR = 0.845; PValue = 0.554; mean CPM = 0.9339; glycoprotein VI (platelet)" ID="ID_1711373997" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL11A2: 1.03-fold Down; FDR = 1; PValue = 0.872; mean CPM = 2.131; collagen, type XI, alpha 2" ID="ID_615424734" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL24A1: 1.04-fold Up; FDR = 1; PValue = 0.898; mean CPM = 1.201; collagen, type XXIV, alpha 1" ID="ID_872986866" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNXB: 1.03-fold Up; FDR = 1; PValue = 0.909; mean CPM = 1.078; tenascin XB" ID="ID_726762633" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB7: 1.01-fold Down; FDR = 1; PValue = 0.968; mean CPM = 2.025; integrin, beta 7" ID="ID_734119164" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD44: No Change; FDR = 1; PValue = 0.981; mean CPM = 487.7; CD44 molecule (Indian blood group)" ID="ID_435735004" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNR: 1.08-fold Down; FDR = 1; PValue = 0.984; mean CPM = 0.8556; tenascin R (restrictin, janusin)" ID="ID_277122743" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Herpes simplex infection: Activated, FDR = 6.45e-05, FWER = 0.000193, PValue = 1.33e-06" ID="ID_1937837591" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TLR2: 8.94-fold Up; FDR = 6.97e-23; PValue = 1.25e-25; mean CPM = 18.41; toll-like receptor 2" ID="ID_908114112" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFIH1: 14.7-fold Up; FDR = 8.74e-23; PValue = 1.68e-25; mean CPM = 49.84; interferon induced with helicase C domain 1" ID="ID_1671913972" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR3: 10.3-fold Up; FDR = 1.95e-21; PValue = 5.6e-24; mean CPM = 35.70; toll-like receptor 3" ID="ID_1749508665" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="OAS1: 41-fold Up; FDR = 1.01e-20; PValue = 3.28e-23; mean CPM = 37.38; Macaca mulatta 2',5'-oligoadenylate synthetase 1, 40/46kDa (OAS1), mRNA." ID="ID_1500828234" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF9: 3.85-fold Up; FDR = 2.6e-19; PValue = 1.12e-21; mean CPM = 106.4; interferon regulatory factor 9" ID="ID_1454846030" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT2: 2.67-fold Up; FDR = 8.02e-19; PValue = 4.03e-21; mean CPM = 185.6; signal transducer and activator of transcription 2, 113kDa" ID="ID_1609342848" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_297941987" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_448960414" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000003602: 4.73-fold Up; FDR = 3.68e-18; PValue = 2.14e-20; mean CPM = 35.47; Uncharacterized protein" ID="ID_1310008729" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DDX58: 6.4-fold Up; FDR = 5.12e-18; PValue = 3.06e-20; mean CPM = 86.14; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58" ID="ID_1136697935" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2AK2: 3.01-fold Up; FDR = 6.08e-18; PValue = 3.74e-20; mean CPM = 47.85; eukaryotic translation initiation factor 2-alpha kinase 2" ID="ID_813976844" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF7: 14.8-fold Up; FDR = 7.66e-18; PValue = 4.82e-20; mean CPM = 11.54; Macaca mulatta interferon regulatory factor 7 (IRF7), mRNA." ID="ID_82526807" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_871236235" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF14: 4.66-fold Up; FDR = 2.46e-16; PValue = 2.07e-18; mean CPM = 36.12; Macaca mulatta tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) (TNFRSF14), mRNA." ID="ID_822044074" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="OAS2: 14.9-fold Up; FDR = 3.5e-15; PValue = 3.41e-17; mean CPM = 85.83; 2'-5'-oligoadenylate synthetase 2, 69/71kDa" ID="ID_1764753301" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAVS: 1.92-fold Down; FDR = 2.7e-09; PValue = 1.02e-10; mean CPM = 29.16; mitochondrial antiviral signaling protein" ID="ID_1200847834" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RNASEL: 1.71-fold Up; FDR = 7.18e-09; PValue = 2.98e-10; mean CPM = 21.59; ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)" ID="ID_1861794960" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_895490638" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_1780146522" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR2: 1.74-fold Up; FDR = 1.85e-06; PValue = 1.44e-07; mean CPM = 26.05; interferon (alpha, beta and omega) receptor 2" ID="ID_926637625" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1887033938" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2AK3: 1.59-fold Down; FDR = 2.47e-06; PValue = 1.96e-07; mean CPM = 33.81; eukaryotic translation initiation factor 2-alpha kinase 3" ID="ID_809362948" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HCFC1: 1.45-fold Down; FDR = 1.15e-05; PValue = 1.1e-06; mean CPM = 107.1; host cell factor C1 (VP16-accessory protein)" ID="ID_1273205956" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF1: 2.6-fold Down; FDR = 1.48e-05; PValue = 1.46e-06; mean CPM = 20.19; TNF receptor-associated factor 1" ID="ID_97586781" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2S1: 1.42-fold Up; FDR = 5.59e-05; PValue = 6.42e-06; mean CPM = 79.87; eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa" ID="ID_199807900" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP2: 1.45-fold Up; FDR = 0.000179; PValue = 2.4e-05; mean CPM = 65.31; TGF-beta activated kinase 1/MAP3K7 binding protein 2" ID="ID_410960607" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS3: 1.69-fold Up; FDR = 0.000994; PValue = 0.000167; mean CPM = 37.76; suppressor of cytokine signaling 3" ID="ID_1455749243" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C1QBP: 1.36-fold Up; FDR = 0.00107; PValue = 0.000183; mean CPM = 83.61; complement component 1, q subcomponent binding protein" ID="ID_1893371599" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR1: 1.31-fold Up; FDR = 0.00151; PValue = 0.000268; mean CPM = 37.77; interferon gamma receptor 1" ID="ID_811093344" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBK1: 1.3-fold Up; FDR = 0.00337; PValue = 0.000674; mean CPM = 30.46; TANK-binding kinase 1" ID="ID_565630994" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_158259257" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_620680148" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR1: 1.27-fold Up; FDR = 0.0101; PValue = 0.00237; mean CPM = 82.39; Uncharacterized protein" ID="ID_1827817067" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SRPK1: 1.24-fold Up; FDR = 0.0118; PValue = 0.00283; mean CPM = 43.50; SRSF protein kinase 1" ID="ID_946981889" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSNK2A2: 1.28-fold Up; FDR = 0.0129; PValue = 0.00314; mean CPM = 19.86; casein kinase 2, alpha prime polypeptide" ID="ID_389403830" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYK2: 1.24-fold Down; FDR = 0.0142; PValue = 0.00354; mean CPM = 42.58; tyrosine kinase 2" ID="ID_66388592" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SFRS6: 1.23-fold Down; FDR = 0.0161; PValue = 0.00409; mean CPM = 92.28; splicing factor, arginine/serine-rich 6" ID="ID_1170174159" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK2: 1.23-fold Down; FDR = 0.0194; PValue = 0.00507; mean CPM = 36.76; cyclin-dependent kinase 2" ID="ID_143985617" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR2: 1.23-fold Up; FDR = 0.0258; PValue = 0.00707; mean CPM = 46.52; interferon gamma receptor 2 (interferon gamma transducer 1)" ID="ID_1486797744" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_1289745940" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_385147282" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FADD: 1.18-fold Down; FDR = 0.0936; PValue = 0.0324; mean CPM = 30.89; Uncharacterized protein" ID="ID_1234744322" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_872035032" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_1101284374" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_1773354932" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_792276728" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SFRS4: 1.15-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 47.62; splicing factor, arginine/serine-rich 4" ID="ID_1958455630" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000039103: 1.67-fold Down; FDR = 0.221; PValue = 0.0927; mean CPM = 1.310; Uncharacterized protein" ID="ID_1310795511" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1A: 1.11-fold Up; FDR = 0.297; PValue = 0.134; mean CPM = 134.7; tumor necrosis factor receptor superfamily, member 1A" ID="ID_1405042674" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP1: 1.12-fold Down; FDR = 0.351; PValue = 0.165; mean CPM = 17.96; TGF-beta activated kinase 1/MAP3K7 binding protein 1" ID="ID_1789151888" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TICAM1: 1.11-fold Down; FDR = 0.398; PValue = 0.192; mean CPM = 26.73; toll-like receptor adaptor molecule 1" ID="ID_413360648" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SFRS5: 1.1-fold Up; FDR = 0.399; PValue = 0.193; mean CPM = 203.9; splicing factor, arginine/serine-rich 5" ID="ID_785810838" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_1362270374" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2AK1: 1.09-fold Up; FDR = 0.499; PValue = 0.258; mean CPM = 34.88; Uncharacterized protein" ID="ID_543029097" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP1CB: 1.08-fold Up; FDR = 0.566; PValue = 0.306; mean CPM = 108.6; protein phosphatase 1, catalytic subunit, beta isozyme" ID="ID_1715923578" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SRSF9: 1.07-fold Down; FDR = 0.595; PValue = 0.326; mean CPM = 49.60; Uncharacterized protein" ID="ID_1230397488" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF3: 1.07-fold Up; FDR = 0.611; PValue = 0.338; mean CPM = 34.56; TNF receptor-associated factor 3" ID="ID_381160079" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2AK4: 1.06-fold Up; FDR = 0.681; PValue = 0.391; mean CPM = 104.8; eukaryotic translation initiation factor 2 alpha kinase 4" ID="ID_519934554" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HCFC2: 1.07-fold Down; FDR = 0.701; PValue = 0.408; mean CPM = 22.13; host cell factor C2" ID="ID_1723941431" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNB1: 1.79-fold Up; FDR = 0.731; PValue = 0.433; mean CPM = 0.8526; interferon, beta 1, fibroblast" ID="ID_1524149503" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_1061298661" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA6: 1.41-fold Down; FDR = 0.807; PValue = 0.504; mean CPM = 0.8019; interferon, alpha 6" ID="ID_1363377212" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SRSF1: 1.05-fold Down; FDR = 0.812; PValue = 0.509; mean CPM = 151.1; Serine/arginine-rich splicing factor 1 isoform 1; Uncharacterized protein" ID="ID_123381179" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYCS: 1.05-fold Up; FDR = 0.854; PValue = 0.565; mean CPM = 93.43; cytochrome c, somatic" ID="ID_182100340" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_240048616" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000040219: 1.08-fold Up; FDR = 0.86; PValue = 0.575; mean CPM = 8.818; Uncharacterized protein" ID="ID_160906761" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_1584700114" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_999215999" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SFRS3: 1.03-fold Up; FDR = 0.899; PValue = 0.631; mean CPM = 170.5; splicing factor, arginine/serine-rich 3" ID="ID_131749368" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF14: 1.16-fold Down; FDR = 0.903; PValue = 0.645; mean CPM = 0.7940; tumor necrosis factor (ligand) superfamily, member 14" ID="ID_381997179" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA13: 1.13-fold Up; FDR = 0.908; PValue = 0.677; mean CPM = 0.7960; interferon, alpha 13" ID="ID_1428507715" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK1: 1.07-fold Up; FDR = 0.908; PValue = 0.682; mean CPM = 14.72; Uncharacterized protein" ID="ID_451287327" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA8: 1.13-fold Down; FDR = 0.911; PValue = 0.702; mean CPM = 0.7910; interferon, alpha 8" ID="ID_1282562322" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKE: 1.03-fold Up; FDR = 0.929; PValue = 0.737; mean CPM = 21.61; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon" ID="ID_1322854784" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FASLG: 1.2-fold Down; FDR = 0.941; PValue = 0.757; mean CPM = 0.8088; Fas ligand (TNF superfamily, member 6)" ID="ID_934421661" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSNK2B: 1.02-fold Down; FDR = 0.956; PValue = 0.787; mean CPM = 77.24; Casein kinase II subunit beta (CK II beta)(Phosvitin)(Protein G5a)" ID="ID_1134734884" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000009289: 1.07-fold Up; FDR = 0.963; PValue = 0.798; mean CPM = 2.536; Uncharacterized protein" ID="ID_381532142" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA14: 1.22-fold Up; FDR = 0.965; PValue = 0.802; mean CPM = 0.8654; interferon, alpha 14" ID="ID_70228188" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_1067070536" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA4: 1.28-fold Down; FDR = 0.983; PValue = 0.829; mean CPM = 0.8584; interferon, alpha 4" ID="ID_1604053881" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PILRA: 1.07-fold Up; FDR = 0.998; PValue = 0.854; mean CPM = 0.9415; paired immunoglobin-like type 2 receptor alpha" ID="ID_1349616601" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR9: 1.01-fold Down; FDR = 1; PValue = 0.859; mean CPM = 21.45; Macaca mulatta toll-like receptor 9 (TLR9), mRNA." ID="ID_1051646700" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SFRS7: 1.01-fold Down; FDR = 1; PValue = 0.873; mean CPM = 94.47; splicing factor, arginine/serine-rich 7, 35kDa" ID="ID_682099523" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="POU2F3: 1.09-fold Down; FDR = 1; PValue = 0.884; mean CPM = 0.8933; POU class 2 homeobox 3" ID="ID_1002085500" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_87831549" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA1: No Change; FDR = 1; PValue = 0.998; mean CPM = 0.8014; interferon, alpha 1" ID="ID_586263956" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Influenza A: Activated, FDR = 0.000133, FWER = 0.000533, PValue = 3.68e-06" ID="ID_900436621" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="IFIH1: 14.7-fold Up; FDR = 8.74e-23; PValue = 1.68e-25; mean CPM = 49.84; interferon induced with helicase C domain 1" ID="ID_688707536" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR3: 10.3-fold Up; FDR = 1.95e-21; PValue = 5.6e-24; mean CPM = 35.70; toll-like receptor 3" ID="ID_740639817" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="OAS1: 41-fold Up; FDR = 1.01e-20; PValue = 3.28e-23; mean CPM = 37.38; Macaca mulatta 2',5'-oligoadenylate synthetase 1, 40/46kDa (OAS1), mRNA." ID="ID_946533046" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF9: 3.85-fold Up; FDR = 2.6e-19; PValue = 1.12e-21; mean CPM = 106.4; interferon regulatory factor 9" ID="ID_1143782753" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRIM25: 3.78-fold Up; FDR = 3.13e-19; PValue = 1.41e-21; mean CPM = 121.6; tripartite motif-containing 25" ID="ID_1996317337" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT2: 2.67-fold Up; FDR = 8.02e-19; PValue = 4.03e-21; mean CPM = 185.6; signal transducer and activator of transcription 2, 113kDa" ID="ID_1576268858" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_1168477058" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1662149015" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000003602: 4.73-fold Up; FDR = 3.68e-18; PValue = 2.14e-20; mean CPM = 35.47; Uncharacterized protein" ID="ID_802278126" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DDX58: 6.4-fold Up; FDR = 5.12e-18; PValue = 3.06e-20; mean CPM = 86.14; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58" ID="ID_330354684" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2AK2: 3.01-fold Up; FDR = 6.08e-18; PValue = 3.74e-20; mean CPM = 47.85; eukaryotic translation initiation factor 2-alpha kinase 2" ID="ID_1850607125" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF7: 14.8-fold Up; FDR = 7.66e-18; PValue = 4.82e-20; mean CPM = 11.54; Macaca mulatta interferon regulatory factor 7 (IRF7), mRNA." ID="ID_359780053" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RSAD2: 37.4-fold Up; FDR = 7.72e-18; PValue = 4.9e-20; mean CPM = 9.742; radical S-adenosyl methionine domain containing 2" ID="ID_1594555689" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CIITA: 45.8-fold Up; FDR = 1.14e-17; PValue = 7.44e-20; mean CPM = 27.80; class II, major histocompatibility complex, transactivator" ID="ID_626948431" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF10: 44.5-fold Up; FDR = 2.83e-16; PValue = 2.4e-18; mean CPM = 6.029; Tumor necrosis factor ligand superfamily member 10 isoform 1; Uncharacterized protein" ID="ID_1014866058" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="OAS2: 14.9-fold Up; FDR = 3.5e-15; PValue = 3.41e-17; mean CPM = 85.83; 2'-5'-oligoadenylate synthetase 2, 69/71kDa" ID="ID_919505511" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA2: 4.21-fold Down; FDR = 2.4e-14; PValue = 2.77e-16; mean CPM = 66.42; heat shock 70kDa protein 2" ID="ID_1956330803" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL33: 5.25-fold Up; FDR = 5.38e-12; PValue = 1.05e-13; mean CPM = 531.4; interleukin 33" ID="ID_1557609818" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAVS: 1.92-fold Down; FDR = 2.7e-09; PValue = 1.02e-10; mean CPM = 29.16; mitochondrial antiviral signaling protein" ID="ID_893516467" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR4: 3.45-fold Up; FDR = 3.1e-09; PValue = 1.19e-10; mean CPM = 7.456; Macaca mulatta toll-like receptor 4 (TLR4), mRNA." ID="ID_1290766376" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA1B: 2.24-fold Down; FDR = 4.33e-09; PValue = 1.71e-10; mean CPM = 44.90; Heat shock 70 kDa protein 1A/1B (Heat shock 70 kDa protein 1/2)(HSP70.1/HSP70.2)(HSP70-1/HSP70-2)" ID="ID_711859999" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RNASEL: 1.71-fold Up; FDR = 7.18e-09; PValue = 2.98e-10; mean CPM = 21.59; ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)" ID="ID_191593896" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA8: 1.64-fold Up; FDR = 1.46e-08; PValue = 6.6e-10; mean CPM = 1881; heat shock 70kDa protein 8" ID="ID_1910006929" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK4: 1.8-fold Up; FDR = 3.31e-08; PValue = 1.64e-09; mean CPM = 12.89; interleukin-1 receptor-associated kinase 4" ID="ID_1001520402" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1099704308" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_55799491" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1213358559" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_1206030436" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NXF1: 1.53-fold Down; FDR = 1.55e-06; PValue = 1.16e-07; mean CPM = 49.36; nuclear RNA export factor 1" ID="ID_427325576" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR2: 1.74-fold Up; FDR = 1.85e-06; PValue = 1.44e-07; mean CPM = 26.05; interferon (alpha, beta and omega) receptor 2" ID="ID_913303147" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_107844809" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2AK3: 1.59-fold Down; FDR = 2.47e-06; PValue = 1.96e-07; mean CPM = 33.81; eukaryotic translation initiation factor 2-alpha kinase 3" ID="ID_1512060270" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K3: 1.45-fold Down; FDR = 7.01e-06; PValue = 6.34e-07; mean CPM = 180.1; mitogen-activated protein kinase kinase 3" ID="ID_1823147143" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_899126131" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2S1: 1.42-fold Up; FDR = 5.59e-05; PValue = 6.42e-06; mean CPM = 79.87; eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa" ID="ID_244998586" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF10D: 1.84-fold Down; FDR = 5.9e-05; PValue = 6.84e-06; mean CPM = 32.06; tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain" ID="ID_1937151996" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF2: 1.34-fold Up; FDR = 0.000403; PValue = 6.01e-05; mean CPM = 39.83; activating transcription factor 2" ID="ID_292550547" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NXT2: 2.01-fold Up; FDR = 0.000588; PValue = 9.2e-05; mean CPM = 5.026; nuclear transport factor 2-like export factor 2" ID="ID_1005164857" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS3: 1.69-fold Up; FDR = 0.000994; PValue = 0.000167; mean CPM = 37.76; suppressor of cytokine signaling 3" ID="ID_38780499" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR1: 1.31-fold Up; FDR = 0.00151; PValue = 0.000268; mean CPM = 37.77; interferon gamma receptor 1" ID="ID_571647325" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBK1: 1.3-fold Up; FDR = 0.00337; PValue = 0.000674; mean CPM = 30.46; TANK-binding kinase 1" ID="ID_1595738757" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_99887296" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_989838711" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL18: 1.5-fold Down; FDR = 0.00981; PValue = 0.0023; mean CPM = 6.489; interleukin 18 (interferon-gamma-inducing factor)" ID="ID_1943165967" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR1: 1.27-fold Up; FDR = 0.0101; PValue = 0.00237; mean CPM = 82.39; Uncharacterized protein" ID="ID_110602962" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYK2: 1.24-fold Down; FDR = 0.0142; PValue = 0.00354; mean CPM = 42.58; tyrosine kinase 2" ID="ID_1418547564" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_57117315" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA6: 2.05-fold Down; FDR = 0.0226; PValue = 0.00604; mean CPM = 2.573; heat shock 70kDa protein 6 (HSP70B')" ID="ID_655993864" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_246609418" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR2: 1.23-fold Up; FDR = 0.0258; PValue = 0.00707; mean CPM = 46.52; interferon gamma receptor 2 (interferon gamma transducer 1)" ID="ID_1755702105" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1525207459" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DNAJB1: 1.18-fold Up; FDR = 0.0756; PValue = 0.0252; mean CPM = 33.66; DnaJ (Hsp40) homolog, subfamily B, member 1" ID="ID_521841529" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NXT1: 1.29-fold Up; FDR = 0.0866; PValue = 0.0295; mean CPM = 6.865; NTF2-like export factor 1" ID="ID_1002560855" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_351556383" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_1917662502" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FDPS: 1.15-fold Down; FDR = 0.126; PValue = 0.0464; mean CPM = 49.16; farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)" ID="ID_230654086" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_1252479037" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_596408556" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_907153310" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000039103: 1.67-fold Down; FDR = 0.221; PValue = 0.0927; mean CPM = 1.310; Uncharacterized protein" ID="ID_600687499" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PYCARD: 1.38-fold Down; FDR = 0.241; PValue = 0.103; mean CPM = 3.110; PYD and CARD domain containing" ID="ID_7536289" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_1769603123" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLRP3: 1.84-fold Down; FDR = 0.32; PValue = 0.147; mean CPM = 0.9630; NLR family, pyrin domain containing 3" ID="ID_248930839" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_797212524" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF10B: 1.13-fold Down; FDR = 0.343; PValue = 0.16; mean CPM = 40.59; tumor necrosis factor receptor superfamily, member 10b" ID="ID_1976457543" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1474418820" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TICAM1: 1.11-fold Down; FDR = 0.398; PValue = 0.192; mean CPM = 26.73; toll-like receptor adaptor molecule 1" ID="ID_872342647" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_731664398" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_862725232" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK12: 1.19-fold Down; FDR = 0.422; PValue = 0.208; mean CPM = 6.569; mitogen-activated protein kinase 12" ID="ID_1199083451" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1524324768" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2AK1: 1.09-fold Up; FDR = 0.499; PValue = 0.258; mean CPM = 34.88; Uncharacterized protein" ID="ID_191480392" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_820912306" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK13: 1.22-fold Down; FDR = 0.536; PValue = 0.284; mean CPM = 3.100; mitogen-activated protein kinase 13" ID="ID_607203486" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_446630307" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2AK4: 1.06-fold Up; FDR = 0.681; PValue = 0.391; mean CPM = 104.8; eukaryotic translation initiation factor 2 alpha kinase 4" ID="ID_1690990890" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NUP98: 1.06-fold Up; FDR = 0.704; PValue = 0.41; mean CPM = 125.0; nucleoporin 98kDa" ID="ID_1916453006" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNB1: 1.79-fold Up; FDR = 0.731; PValue = 0.433; mean CPM = 0.8526; interferon, beta 1, fibroblast" ID="ID_177695020" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF10A: 1.06-fold Down; FDR = 0.732; PValue = 0.434; mean CPM = 42.75; tumor necrosis factor receptor superfamily, member 10a" ID="ID_1838225328" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYCS: 1.05-fold Up; FDR = 0.854; PValue = 0.565; mean CPM = 93.43; cytochrome c, somatic" ID="ID_1548594382" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000040219: 1.08-fold Up; FDR = 0.86; PValue = 0.575; mean CPM = 8.818; Uncharacterized protein" ID="ID_396293797" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_78970448" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR7: 1.37-fold Down; FDR = 0.878; PValue = 0.597; mean CPM = 0.8402; toll-like receptor 7" ID="ID_1391496966" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NXF2B: 1.25-fold Up; FDR = 0.881; PValue = 0.601; mean CPM = 0.9156; nuclear RNA export factor 2B" ID="ID_532482315" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_382736673" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAE1: 1.03-fold Up; FDR = 0.92; PValue = 0.723; mean CPM = 25.49; RAE1 RNA export 1 homolog (S. pombe)" ID="ID_936607351" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKE: 1.03-fold Up; FDR = 0.929; PValue = 0.737; mean CPM = 21.61; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon" ID="ID_1044932536" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DNAJC3: 1.02-fold Down; FDR = 0.931; PValue = 0.742; mean CPM = 43.82; DnaJ (Hsp40) homolog, subfamily C, member 3" ID="ID_142503337" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FASLG: 1.2-fold Down; FDR = 0.941; PValue = 0.757; mean CPM = 0.8088; Fas ligand (TNF superfamily, member 6)" ID="ID_1769856046" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_791975241" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000009289: 1.07-fold Up; FDR = 0.963; PValue = 0.798; mean CPM = 2.536; Uncharacterized protein" ID="ID_1403543639" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_1823163365" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NXF3: 1.03-fold Up; FDR = 1; PValue = 0.882; mean CPM = 2.392; nuclear RNA export factor 3" ID="ID_1243046344" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP9: 1.01-fold Up; FDR = 1; PValue = 0.908; mean CPM = 19.86; caspase 9, apoptosis-related cysteine peptidase" ID="ID_1332147552" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_204866733" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Chemokine signaling pathway: Activated, FDR = 0.000229, FWER = 0.00115, PValue = 7.9e-06" ID="ID_1638780649" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CXCL10: 462-fold Up; FDR = 1.01e-21; PValue = 2.65e-24; mean CPM = 286.2; Macaca mulatta chemokine (C-X-C motif) ligand 10 (CXCL10), mRNA." ID="ID_664467340" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL11: 256-fold Up; FDR = 1e-19; PValue = 3.96e-22; mean CPM = 84.82; chemokine (C-X-C motif) ligand 11" ID="ID_661788191" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL9: 345-fold Up; FDR = 4.16e-19; PValue = 1.97e-21; mean CPM = 175.7; Macaca mulatta chemokine (C-X-C motif) ligand 9 (CXCL9), mRNA." ID="ID_1276235172" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT2: 2.67-fold Up; FDR = 8.02e-19; PValue = 4.03e-21; mean CPM = 185.6; signal transducer and activator of transcription 2, 113kDa" ID="ID_1693619232" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_615453863" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1927259724" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL2: 24.6-fold Up; FDR = 1.83e-15; PValue = 1.69e-17; mean CPM = 668.2; Macaca mulatta chemokine (C-C motif) ligand 2 (CCL2), mRNA." ID="ID_1267475700" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG10: 2.27-fold Up; FDR = 1.24e-13; PValue = 1.66e-15; mean CPM = 24.29; guanine nucleotide binding protein (G protein), gamma 10" ID="ID_736412849" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC4: 7.09-fold Down; FDR = 1.82e-12; PValue = 3.1e-14; mean CPM = 6.421; SHC (Src homology 2 domain containing) family, member 4" ID="ID_1627916104" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CX3CL1: 6.16-fold Up; FDR = 5.13e-12; PValue = 1e-13; mean CPM = 14.86; chemokine (C-X3-C motif) ligand 1" ID="ID_464456004" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_1952751469" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY6: 1.89-fold Down; FDR = 1.9e-10; PValue = 5.38e-12; mean CPM = 141.3; adenylate cyclase 6" ID="ID_242256638" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL13: 12.3-fold Up; FDR = 4.33e-10; PValue = 1.35e-11; mean CPM = 3.824; chemokine (C-C motif) ligand 13" ID="ID_341688565" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNB4: 2.14-fold Up; FDR = 2.52e-09; PValue = 9.35e-11; mean CPM = 33.45; guanine nucleotide binding protein (G protein), beta polypeptide 4" ID="ID_1951814115" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_885354054" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL7: 8.24-fold Up; FDR = 6.67e-09; PValue = 2.75e-10; mean CPM = 8.249; chemokine (C-C motif) ligand 7" ID="ID_84659849" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1933108494" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL16: 3.58-fold Up; FDR = 1.19e-07; PValue = 6.74e-09; mean CPM = 6.893; chemokine (C-X-C motif) ligand 16" ID="ID_1780763318" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2B: 3.54-fold Up; FDR = 1.24e-07; PValue = 7.07e-09; mean CPM = 5.971; PTK2B protein tyrosine kinase 2 beta" ID="ID_839913066" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1B: 1.55-fold Up; FDR = 2.39e-07; PValue = 1.46e-08; mean CPM = 135.3; Ras-related protein Rap-1b; Ras-related protein Rap-1b isoform 1; Uncharacterized protein" ID="ID_447649227" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL5: 6.74-fold Up; FDR = 2.65e-07; PValue = 1.64e-08; mean CPM = 30.35; chemokine (C-C motif) ligand 5" ID="ID_112995857" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG11: 1.65-fold Up; FDR = 2.71e-07; PValue = 1.68e-08; mean CPM = 86.60; guanine nucleotide binding protein (G protein), gamma 11" ID="ID_239065596" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_718576077" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCB1: 1.71-fold Up; FDR = 1.31e-06; PValue = 9.73e-08; mean CPM = 34.36; phospholipase C, beta 1 (phosphoinositide-specific)" ID="ID_552112811" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_703311493" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_131265102" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_1132953428" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADRBK1: 1.5-fold Down; FDR = 3.36e-06; PValue = 2.76e-07; mean CPM = 46.25; adrenergic, beta, receptor kinase 1" ID="ID_1680600603" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1186374666" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL11: 6.86-fold Up; FDR = 2.69e-05; PValue = 2.82e-06; mean CPM = 4.204; chemokine (C-C motif) ligand 11" ID="ID_1964215340" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAI1: 1.47-fold Up; FDR = 5.94e-05; PValue = 6.9e-06; mean CPM = 97.19; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1" ID="ID_689438349" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNB3: 1.91-fold Down; FDR = 0.000162; PValue = 2.14e-05; mean CPM = 7.202; guanine nucleotide binding protein (G protein), beta polypeptide 3" ID="ID_764438663" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACA: 1.36-fold Down; FDR = 0.000167; PValue = 2.22e-05; mean CPM = 37.75; protein kinase, cAMP-dependent, catalytic, alpha" ID="ID_442391971" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCAR1: 1.36-fold Up; FDR = 0.000193; PValue = 2.61e-05; mean CPM = 210.4; breast cancer anti-estrogen resistance 1" ID="ID_1189713422" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCB4: 1.75-fold Down; FDR = 0.00025; PValue = 3.52e-05; mean CPM = 6.730; phospholipase C, beta 4" ID="ID_561534955" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASGRP2: 2.4-fold Up; FDR = 0.000359; PValue = 5.28e-05; mean CPM = 5.834; Uncharacterized protein" ID="ID_1627599347" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PREX1: 1.34-fold Down; FDR = 0.000592; PValue = 9.28e-05; mean CPM = 89.02; phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1" ID="ID_1341430471" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK3: 2.31-fold Up; FDR = 0.00186; PValue = 0.000342; mean CPM = 2.154; Janus kinase 3" ID="ID_1388288776" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCR4: 4.65-fold Down; FDR = 0.00226; PValue = 0.000426; mean CPM = 2.073; chemokine (C-X-C motif) receptor 4" ID="ID_669613871" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHOA: 1.28-fold Down; FDR = 0.00295; PValue = 0.000575; mean CPM = 277.8; ras homolog gene family, member A" ID="ID_1562347924" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKX: 1.31-fold Down; FDR = 0.00331; PValue = 0.000658; mean CPM = 24.94; protein kinase, X-linked" ID="ID_443476504" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1B: 1.43-fold Up; FDR = 0.00346; PValue = 0.000693; mean CPM = 12.81; RAP1B, member of RAS oncogene family" ID="ID_470569443" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG12: 1.31-fold Up; FDR = 0.00387; PValue = 0.000792; mean CPM = 24.97; guanine nucleotide binding protein (G protein), gamma 12" ID="ID_155951035" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL3: 3.28-fold Up; FDR = 0.00459; PValue = 0.000963; mean CPM = 50.55; chemokine (C-X-C motif) ligand 3" ID="ID_1426732579" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV3: 1.82-fold Down; FDR = 0.00463; PValue = 0.000973; mean CPM = 7.044; vav 3 guanine nucleotide exchange factor" ID="ID_1547347983" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAI3: 1.26-fold Up; FDR = 0.00487; PValue = 0.00103; mean CPM = 113.8; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3" ID="ID_295203841" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1345737138" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR9: 3.89-fold Down; FDR = 0.00547; PValue = 0.00117; mean CPM = 0.9346; chemokine (C-C motif) receptor 9" ID="ID_1673747702" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL1: 2.18-fold Up; FDR = 0.00609; PValue = 0.00133; mean CPM = 45.92; chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)" ID="ID_676976154" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL8: 3.3-fold Up; FDR = 0.00609; PValue = 0.00133; mean CPM = 1.313; chemokine (C-C motif) ligand 8" ID="ID_825824432" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WASL: 1.26-fold Up; FDR = 0.00781; PValue = 0.00177; mean CPM = 33.90; Wiskott-Aldrich syndrome-like" ID="ID_1496953486" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PF4V1: 2.28-fold Down; FDR = 0.00877; PValue = 0.00202; mean CPM = 3.258; platelet factor 4 variant 1" ID="ID_1296496365" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY9: 1.32-fold Down; FDR = 0.00986; PValue = 0.00231; mean CPM = 84.04; adenylate cyclase 9" ID="ID_328334638" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL20: 2.09-fold Up; FDR = 0.0108; PValue = 0.00256; mean CPM = 60.21; Macaca mulatta chemokine (C-C motif) ligand 20 (CCL20), mRNA." ID="ID_253363027" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCZ: 1.51-fold Up; FDR = 0.0152; PValue = 0.00381; mean CPM = 10.46; protein kinase C, zeta" ID="ID_765710874" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRK4: 1.55-fold Down; FDR = 0.0188; PValue = 0.0049; mean CPM = 5.871; G protein-coupled receptor kinase 4" ID="ID_9215115" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1240689609" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL8: 2.33-fold Up; FDR = 0.0209; PValue = 0.00552; mean CPM = 2326; interleukin 8" ID="ID_580068681" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DOCK2: 1.4-fold Up; FDR = 0.0216; PValue = 0.00573; mean CPM = 37.89; dedicator of cytokinesis 2" ID="ID_1102104755" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1122589959" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC2: 2.96-fold Up; FDR = 0.0309; PValue = 0.00872; mean CPM = 0.9737; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)" ID="ID_1841853908" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL18: 3.2-fold Down; FDR = 0.0322; PValue = 0.00915; mean CPM = 0.9111; chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)" ID="ID_1867790144" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR7: 1.48-fold Down; FDR = 0.0357; PValue = 0.0103; mean CPM = 13.37; chemokine (C-C motif) receptor 7" ID="ID_483764714" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_62588133" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KRAS: 1.35-fold Down; FDR = 0.0401; PValue = 0.0119; mean CPM = 13.10; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog" ID="ID_1629210175" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY5: 2.17-fold Down; FDR = 0.042; PValue = 0.0125; mean CPM = 1.219; adenylate cyclase 5" ID="ID_833881255" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY7: 1.24-fold Down; FDR = 0.0434; PValue = 0.013; mean CPM = 157.2; adenylate cyclase 7" ID="ID_1631903522" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCB2: 3.68-fold Down; FDR = 0.0481; PValue = 0.0147; mean CPM = 1.557; Uncharacterized protein" ID="ID_1295604284" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NRAS: 1.2-fold Down; FDR = 0.0546; PValue = 0.017; mean CPM = 32.39; neuroblastoma RAS viral (v-ras) oncogene homolog" ID="ID_1547471407" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL28: 2.67-fold Up; FDR = 0.0616; PValue = 0.0197; mean CPM = 1.020; chemokine (C-C motif) ligand 28" ID="ID_1156119262" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL3: 2.04-fold Down; FDR = 0.067; PValue = 0.0218; mean CPM = 3.575; chemokine (C-C motif) ligand 3" ID="ID_369298436" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_906475072" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TIAM1: 1.23-fold Up; FDR = 0.0747; PValue = 0.0248; mean CPM = 38.38; T-cell lymphoma invasion and metastasis 1" ID="ID_613043862" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCR5: 2.19-fold Down; FDR = 0.0766; PValue = 0.0256; mean CPM = 1.341; chemokine (C-X-C motif) receptor 5" ID="ID_408385614" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1A: 1.17-fold Up; FDR = 0.0888; PValue = 0.0304; mean CPM = 37.16; RAP1A, member of RAS oncogene family" ID="ID_1583097823" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3A: 1.18-fold Down; FDR = 0.097; PValue = 0.0338; mean CPM = 25.14; Glycogen synthase kinase-3 alpha; Uncharacterized protein" ID="ID_888646179" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS2: 1.17-fold Up; FDR = 0.1; PValue = 0.0353; mean CPM = 31.79; son of sevenless homolog 2 (Drosophila)" ID="ID_392579159" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARRB1: 1.35-fold Down; FDR = 0.107; PValue = 0.0382; mean CPM = 4.106; arrestin, beta 1" ID="ID_173326298" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_246780204" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG2: 1.64-fold Up; FDR = 0.117; PValue = 0.0421; mean CPM = 2.320; guanine nucleotide binding protein (G protein), gamma 2" ID="ID_1799441623" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAI2: 1.15-fold Down; FDR = 0.134; PValue = 0.0501; mean CPM = 356.3; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2" ID="ID_1155578855" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_487092595" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG3: 1.6-fold Down; FDR = 0.155; PValue = 0.0601; mean CPM = 1.706; guanine nucleotide binding protein (G protein), gamma 3" ID="ID_91852733" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ROCK2: 1.14-fold Up; FDR = 0.166; PValue = 0.065; mean CPM = 247.7; Rho-associated, coiled-coil containing protein kinase 2" ID="ID_41116400" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC2: 1.34-fold Down; FDR = 0.191; PValue = 0.0774; mean CPM = 7.313; SHC (Src homology 2 domain containing) transforming protein 2" ID="ID_1931936893" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1010547147" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL6: 1.5-fold Down; FDR = 0.2; PValue = 0.082; mean CPM = 258.8; chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)" ID="ID_1564512130" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_1896538791" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BRAF: 1.14-fold Down; FDR = 0.228; PValue = 0.0964; mean CPM = 24.98; v-raf murine sarcoma viral oncogene homolog B1" ID="ID_1635292405" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_862358305" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY4: 1.24-fold Up; FDR = 0.328; PValue = 0.151; mean CPM = 8.390; adenylate cyclase 4" ID="ID_253165048" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_1624733179" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ELMO1: 1.82-fold Down; FDR = 0.348; PValue = 0.163; mean CPM = 2.504; engulfment and cell motility 1" ID="ID_557116487" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG7: 1.75-fold Down; FDR = 0.366; PValue = 0.174; mean CPM = 0.9647; guanine nucleotide binding protein (G protein), gamma 7" ID="ID_1321095483" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRKL: 1.11-fold Up; FDR = 0.371; PValue = 0.176; mean CPM = 34.10; v-crk sarcoma virus CT10 oncogene homolog (avian)-like" ID="ID_1942666481" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1752831902" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2: 1.1-fold Up; FDR = 0.394; PValue = 0.191; mean CPM = 102.5; PTK2 protein tyrosine kinase 2" ID="ID_1838068338" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL14: 1.14-fold Up; FDR = 0.405; PValue = 0.197; mean CPM = 133.7; Uncharacterized protein" ID="ID_190740342" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL26: 1.74-fold Down; FDR = 0.423; PValue = 0.208; mean CPM = 0.8756; chemokine (C-C motif) ligand 26" ID="ID_1353331197" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1399520280" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR5: 1.56-fold Down; FDR = 0.487; PValue = 0.249; mean CPM = 1.064; chemokine (C-C motif) receptor 5" ID="ID_920391655" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL12: 1.27-fold Down; FDR = 0.488; PValue = 0.251; mean CPM = 4.383; chemokine (C-X-C motif) ligand 12" ID="ID_742996645" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGR: 1.63-fold Up; FDR = 0.516; PValue = 0.269; mean CPM = 1.191; Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog" ID="ID_1299690105" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG4: 1.65-fold Down; FDR = 0.524; PValue = 0.275; mean CPM = 0.8771; guanine nucleotide binding protein (G protein), gamma 4" ID="ID_1898856985" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_744003283" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOXO3: 1.08-fold Down; FDR = 0.55; PValue = 0.294; mean CPM = 48.45; forkhead box O3" ID="ID_439118342" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNB1: 1.08-fold Down; FDR = 0.565; PValue = 0.305; mean CPM = 299.4; guanine nucleotide binding protein (G protein), beta polypeptide 1" ID="ID_1868746066" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PARD3: 1.07-fold Up; FDR = 0.581; PValue = 0.316; mean CPM = 129.4; par-3 partitioning defective 3 homolog (C. elegans)" ID="ID_61496396" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC3: 1.37-fold Down; FDR = 0.584; PValue = 0.318; mean CPM = 1.193; SHC-transforming protein 3; Uncharacterized protein" ID="ID_1982846204" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDC42: 1.07-fold Down; FDR = 0.608; PValue = 0.335; mean CPM = 91.67; cell division cycle 42" ID="ID_1180527584" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNGT2: 1.9-fold Up; FDR = 0.613; PValue = 0.339; mean CPM = 0.8227; guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2" ID="ID_1205148098" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000001259: 1.31-fold Down; FDR = 0.663; PValue = 0.378; mean CPM = 3.829; Uncharacterized protein" ID="ID_1787872311" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CX3CR1: 2.01-fold Up; FDR = 0.678; PValue = 0.389; mean CPM = 0.8149; chemokine (C-X3-C motif) receptor 1" ID="ID_811081634" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNB2: 1.06-fold Down; FDR = 0.685; PValue = 0.395; mean CPM = 129.1; guanine nucleotide binding protein (G protein), beta polypeptide 2" ID="ID_1305344055" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCD: 1.06-fold Up; FDR = 0.696; PValue = 0.404; mean CPM = 37.45; protein kinase C, delta" ID="ID_1796351610" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADRBK2: 1.11-fold Down; FDR = 0.715; PValue = 0.419; mean CPM = 8.977; adrenergic, beta, receptor kinase 2" ID="ID_1340494172" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCB: 1.86-fold Up; FDR = 0.727; PValue = 0.43; mean CPM = 0.8705; protein kinase C, beta" ID="ID_908019113" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG13: 1.67-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8104; guanine nucleotide binding protein (G protein), gamma 13" ID="ID_241581907" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WAS: 1.37-fold Down; FDR = 0.771; PValue = 0.469; mean CPM = 0.9085; Wiskott-Aldrich syndrome" ID="ID_1597429924" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL1: 1.56-fold Up; FDR = 0.772; PValue = 0.47; mean CPM = 0.8202; chemokine (C-C motif) ligand 1" ID="ID_499136917" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRK: 1.05-fold Up; FDR = 0.791; PValue = 0.488; mean CPM = 59.92; v-crk sarcoma virus CT10 oncogene homolog (avian)" ID="ID_1843354030" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACG: 1.51-fold Down; FDR = 0.795; PValue = 0.491; mean CPM = 0.8026; protein kinase, cAMP-dependent, catalytic, gamma" ID="ID_1830450957" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HCK: 1.3-fold Down; FDR = 0.797; PValue = 0.494; mean CPM = 0.9272; Uncharacterized protein" ID="ID_1173525170" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR6: 1.51-fold Down; FDR = 0.807; PValue = 0.504; mean CPM = 0.8112; Macaca mulatta chemokine (C-C motif) receptor 6 (CCR6), mRNA." ID="ID_1760545751" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL27: 1.17-fold Up; FDR = 0.817; PValue = 0.515; mean CPM = 1.645; chemokine (C-C motif) ligand 27" ID="ID_1493461455" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRK5: 1.09-fold Up; FDR = 0.82; PValue = 0.519; mean CPM = 11.78; G protein-coupled receptor kinase 5" ID="ID_1820484596" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR2: 1.51-fold Up; FDR = 0.823; PValue = 0.523; mean CPM = 0.8333; chemokine (C-C motif) receptor 2" ID="ID_1027606053" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR4: 1.74-fold Up; FDR = 0.831; PValue = 0.533; mean CPM = 0.8536; chemokine (C-C motif) receptor 4" ID="ID_968033450" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XCL1: 1.39-fold Up; FDR = 0.838; PValue = 0.544; mean CPM = 0.8038; chemokine (C motif) ligand 1" ID="ID_1015465108" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1770032319" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV1: 1.25-fold Down; FDR = 0.858; PValue = 0.572; mean CPM = 0.9515; vav 1 guanine nucleotide exchange factor" ID="ID_1955474802" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY2: 1.18-fold Down; FDR = 0.864; PValue = 0.58; mean CPM = 1.755; adenylate cyclase 2 (brain)" ID="ID_1595241838" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL16: 1.27-fold Up; FDR = 0.865; PValue = 0.581; mean CPM = 0.7999; chemokine (C-C motif) ligand 16" ID="ID_940720881" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY8: 1.28-fold Up; FDR = 0.891; PValue = 0.614; mean CPM = 0.8757; adenylate cyclase 8 (brain)" ID="ID_1386596569" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XCL1: 1.24-fold Down; FDR = 0.899; PValue = 0.635; mean CPM = 0.7954; Macaca mulatta chemokine (C motif) ligand 1 (XCL1), mRNA." ID="ID_1242431160" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XCL1: 1.24-fold Down; FDR = 0.899; PValue = 0.635; mean CPM = 0.7954; Macaca mulatta chemokine (C motif) ligand 1 (XCL1), mRNA." ID="ID_779841848" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000021684: 1.44-fold Up; FDR = 0.903; PValue = 0.662; mean CPM = 0.8513; Uncharacterized protein" ID="ID_1472773168" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR3: 1.43-fold Up; FDR = 0.906; PValue = 0.665; mean CPM = 0.8397; chemokine (C-C motif) receptor 3" ID="ID_1810805092" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY1: 1.13-fold Down; FDR = 0.908; PValue = 0.682; mean CPM = 1.243; adenylate cyclase 1 (brain)" ID="ID_830494115" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL14: 1.15-fold Up; FDR = 0.909; PValue = 0.69; mean CPM = 0.7938; chemokine (C-C motif) ligand 14" ID="ID_789733418" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACB: 1.03-fold Up; FDR = 0.911; PValue = 0.694; mean CPM = 30.10; protein kinase, cAMP-dependent, catalytic, beta" ID="ID_1906319445" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK1: 1.03-fold Down; FDR = 0.911; PValue = 0.705; mean CPM = 18.65; p21 protein (Cdc42/Rac)-activated kinase 1" ID="ID_64955258" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR1: 1.24-fold Up; FDR = 0.915; PValue = 0.714; mean CPM = 0.8590; Macaca mulatta chemokine (C-C motif) receptor 1 (CCR1), mRNA." ID="ID_1210420869" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_677694415" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG5: 1.02-fold Down; FDR = 0.952; PValue = 0.781; mean CPM = 21.93; guanine nucleotide binding protein (G protein), gamma 5" ID="ID_1349012519" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_791720864" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XCR1: 1.09-fold Up; FDR = 0.971; PValue = 0.812; mean CPM = 0.8071; chemokine (C motif) receptor 1" ID="ID_1663809169" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL21: 1.09-fold Down; FDR = 0.972; PValue = 0.813; mean CPM = 1.083; chemokine (C-C motif) ligand 21" ID="ID_1787528050" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRK1: 1.21-fold Up; FDR = 0.987; PValue = 0.837; mean CPM = 0.8126; G protein-coupled receptor kinase 1" ID="ID_780361520" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG8: 1.11-fold Down; FDR = 0.989; PValue = 0.84; mean CPM = 0.8494; guanine nucleotide binding protein (G protein), gamma 8" ID="ID_745347227" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR8: 1.15-fold Down; FDR = 0.999; PValue = 0.857; mean CPM = 0.8181; chemokine (C-C motif) receptor 8" ID="ID_1097197227" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY3: 1.01-fold Up; FDR = 1; PValue = 0.871; mean CPM = 34.92; adenylate cyclase 3" ID="ID_175109001" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNGT1: 1.05-fold Up; FDR = 1; PValue = 0.871; mean CPM = 0.8362; guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1" ID="ID_38676971" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITK: 1.07-fold Up; FDR = 1; PValue = 0.871; mean CPM = 0.9033; IL2-inducible T-cell kinase" ID="ID_491075928" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL25: 1.05-fold Down; FDR = 1; PValue = 0.872; mean CPM = 1.770; chemokine (C-C motif) ligand 25" ID="ID_1289505215" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL22: 1.13-fold Down; FDR = 1; PValue = 0.872; mean CPM = 0.8179; chemokine (C-C motif) ligand 22" ID="ID_1376821202" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNB5: 1.04-fold Down; FDR = 1; PValue = 0.881; mean CPM = 1.533; guanine nucleotide binding protein (G protein), beta 5" ID="ID_377818089" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR10: 1.01-fold Down; FDR = 1; PValue = 0.929; mean CPM = 4.275; chemokine (C-C motif) receptor 10" ID="ID_87944660" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCR2: 1.14-fold Up; FDR = 1; PValue = 0.929; mean CPM = 0.8384; chemokine (C-X-C motif) receptor 2" ID="ID_396726173" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCR3: 1.03-fold Up; FDR = 1; PValue = 0.943; mean CPM = 0.9843; chemokine (C-X-C motif) receptor 3" ID="ID_111653414" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPBP: 1.16-fold Up; FDR = 1; PValue = 0.95; mean CPM = 0.8406; pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)" ID="ID_1154073464" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_664431171" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL23: 1.03-fold Down; FDR = 1; PValue = 0.963; mean CPM = 0.9423; Macaca mulatta chemokine (C-C motif) ligand 23 (CCL23), mRNA." ID="ID_815039956" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV2: No Change; FDR = 1; PValue = 0.976; mean CPM = 25.65; vav 2 guanine nucleotide exchange factor" ID="ID_1859610125" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRK7: 1.04-fold Down; FDR = 1; PValue = 0.982; mean CPM = 0.8188; G protein-coupled receptor kinase 7" ID="ID_145623915" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL17: 1.01-fold Up; FDR = 1; PValue = 0.993; mean CPM = 0.8083; Macaca mulatta chemokine (C-C motif) ligand 17 (CCL17), mRNA." ID="ID_1206316799" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL24: 1.01-fold Up; FDR = 1; PValue = 0.999; mean CPM = 0.8072; Uncharacterized protein" ID="ID_1794419241" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL13: No Change; FDR = 1; PValue = 1; mean CPM = 0.7851; chemokine (C-X-C motif) ligand 13" ID="ID_734033763" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCR1: No Change; FDR = 1; PValue = 1; mean CPM = 0.7827; chemokine (C-X-C motif) receptor 1" ID="ID_54650227" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PF4: 1.04-fold Up; FDR = 1; PValue = 1; mean CPM = 0.8136; platelet factor 4" ID="ID_1924918544" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Antigen processing and presentation: Activated, FDR = 0.00027, FWER = 0.00162, PValue = 1.12e-05" ID="ID_192770557" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TAP1: 8.86-fold Up; FDR = 4.25e-27; PValue = 3.99e-31; mean CPM = 524.4; Antigen peptide transporter 1 (APT1)(Peptide transporter TAP1)(ATP-binding cassette sub-family B member 2)(Peptide supply factor 1)(Peptide transporter PSF1)(PSF-1)(Peptide transporter involved in antigen processing 1)(Really interesting new gene 4 /.../n)" ID="ID_1628850037" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014803: 6.92-fold Up; FDR = 4.41e-27; PValue = 6.21e-31; mean CPM = 361.1; Uncharacterized protein" ID="ID_231080131" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTSS: 17.2-fold Up; FDR = 6.21e-25; PValue = 3.79e-28; mean CPM = 42.75; cathepsin S" ID="ID_1574572473" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSME1: 5.25-fold Up; FDR = 7.8e-24; PValue = 9.53e-27; mean CPM = 157.6; Uncharacterized protein" ID="ID_759194488" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000027180: 6.97-fold Up; FDR = 1.24e-21; PValue = 3.39e-24; mean CPM = 285.4; Uncharacterized protein" ID="ID_936595428" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000027180: 6.97-fold Up; FDR = 1.24e-21; PValue = 3.39e-24; mean CPM = 285.4; Uncharacterized protein" ID="ID_1678749762" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000005183: 4.07-fold Up; FDR = 2.87e-21; PValue = 8.51e-24; mean CPM = 164.7; Uncharacterized protein" ID="ID_225065263" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000005183: 4.07-fold Up; FDR = 2.87e-21; PValue = 8.51e-24; mean CPM = 164.7; Uncharacterized protein" ID="ID_705124178" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-B: 6.07-fold Up; FDR = 2.71e-19; PValue = 1.2e-21; mean CPM = 2098; Uncharacterized protein" ID="ID_1336844707" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CIITA: 45.8-fold Up; FDR = 1.14e-17; PValue = 7.44e-20; mean CPM = 27.80; class II, major histocompatibility complex, transactivator" ID="ID_1434700396" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD74: 104-fold Up; FDR = 6e-17; PValue = 4.54e-19; mean CPM = 141.5; CD74 molecule, major histocompatibility complex, class II invariant chain" ID="ID_934858045" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DMB: 17.5-fold Up; FDR = 2.77e-15; PValue = 2.66e-17; mean CPM = 9.464; HLA class II histocompatibility antigen, DM beta chain Precursor (MHC class II antigen DMB)(Really interesting new gene 7 protein)" ID="ID_610472475" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DPA1: 107-fold Up; FDR = 5.97e-15; PValue = 6.11e-17; mean CPM = 17.08; HLA class II histocompatibility antigen, DP alpha 1 chain Precursor (HLA-SB alpha chain)(MHC class II DP3-alpha)(DP(W3))(DP(W4))" ID="ID_1850305734" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DQB1: 31.1-fold Up; FDR = 6.93e-13; PValue = 1.1e-14; mean CPM = 6.675; Macaca mulatta MHC class II antigen (MAMU-DRB), mRNA." ID="ID_1170578946" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA1: 15.1-fold Up; FDR = 1.9e-08; PValue = 8.86e-10; mean CPM = 3.665; HLA class II histocompatibility antigen, DQ alpha 1 chain precursor" ID="ID_1603067122" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DPB1: 7.73-fold Up; FDR = 4.73e-08; PValue = 2.45e-09; mean CPM = 1.528; Macaca mulatta major histocompatibility complex, class II, DP beta (MAMU-DPB), mRNA." ID="ID_1090574445" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTSL1: 1.84-fold Up; FDR = 6.74e-08; PValue = 3.62e-09; mean CPM = 326.4; cathepsin L1" ID="ID_1496005884" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RFX5: 1.45-fold Up; FDR = 2.02e-06; PValue = 1.58e-07; mean CPM = 51.69; regulatory factor X, 5 (influences HLA class II expression)" ID="ID_1022095988" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB1: 1.21-fold Up; FDR = 0.0313; PValue = 0.00884; mean CPM = 36.07; cAMP responsive element binding protein 1" ID="ID_565964247" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DOA: 2.74-fold Up; FDR = 0.0694; PValue = 0.0227; mean CPM = 0.9089; HLA class II histocompatibility antigen, DO alpha chain Precursor (MHC class II antigen DOA)(MHC DZ alpha)(MHC DN-alpha)" ID="ID_655129815" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RFXANK: 1.15-fold Up; FDR = 0.166; PValue = 0.0651; mean CPM = 33.20; regulatory factor X-associated ankyrin-containing protein" ID="ID_1026384280" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFYA: 1.14-fold Up; FDR = 0.174; PValue = 0.069; mean CPM = 34.54; nuclear transcription factor Y, alpha" ID="ID_543330078" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014796: 1.77-fold Up; FDR = 0.381; PValue = 0.182; mean CPM = 0.9085; Uncharacterized protein" ID="ID_1098448714" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTSB: 1.09-fold Up; FDR = 0.489; PValue = 0.251; mean CPM = 270.7; cathepsin B" ID="ID_1429871664" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFYB: 1.1-fold Up; FDR = 0.547; PValue = 0.292; mean CPM = 15.90; nuclear transcription factor Y, beta" ID="ID_1372064865" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RFXAP: 1.18-fold Up; FDR = 0.553; PValue = 0.296; mean CPM = 3.588; regulatory factor X-associated protein" ID="ID_1670543533" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD4: 1.27-fold Up; FDR = 0.807; PValue = 0.503; mean CPM = 1.122; CD4 molecule" ID="ID_68938637" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_1078075789" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000024066: 1.25-fold Up; FDR = 0.896; PValue = 0.621; mean CPM = 0.7972; Uncharacterized protein" ID="ID_228200526" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DRB: 1.28-fold Up; FDR = 0.898; PValue = 0.624; mean CPM = 0.8112; MHC class II antigen; Uncharacterized protein" ID="ID_310589576" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_1476177742" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KLRC1: 1.14-fold Down; FDR = 0.903; PValue = 0.653; mean CPM = 1.817; killer cell lectin-like receptor subfamily C, member 1" ID="ID_48536869" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA2: 1.13-fold Up; FDR = 0.908; PValue = 0.681; mean CPM = 0.7877; HLA class II histocompatibility antigen, DQ alpha 2 chain Precursor (HLA class II histocompatibility antigen, DQ(6) alpha chain)(DX alpha chain)(HLA-DQA1)" ID="ID_1527650662" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KIR3DL2: 1.18-fold Down; FDR = 0.944; PValue = 0.764; mean CPM = 0.8149; Macaca mulatta killer immunoglobulin-like receptor KIR3DL20 (KIR3DL20), mRNA." ID="ID_977756113" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSME3: No Change; FDR = 1; PValue = 0.946; mean CPM = 64.75; proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)" ID="ID_1933792915" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LGMN: No Change; FDR = 1; PValue = 0.967; mean CPM = 458.0; legumain" ID="ID_1121508021" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD8A: No Change; FDR = 1; PValue = 0.98; mean CPM = 0.8052; CD8a molecule" ID="ID_1943493369" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KLRD1: No Change; FDR = 1; PValue = 1; mean CPM = 0.7825; Macaca mulatta killer cell lectin-like receptor subfamily D, member 1 (KLRD1), mRNA." ID="ID_1164699663" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Cytokine-cytokine receptor interaction: Activated, FDR = 0.000616, FWER = 0.00431, PValue = 2.97e-05" ID="ID_1716633004" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TNFSF13B: 123-fold Up; FDR = 9.32e-25; PValue = 7.44e-28; mean CPM = 49.02; tumor necrosis factor (ligand) superfamily, member 13b" ID="ID_228699848" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL10: 462-fold Up; FDR = 1.01e-21; PValue = 2.65e-24; mean CPM = 286.2; Macaca mulatta chemokine (C-X-C motif) ligand 10 (CXCL10), mRNA." ID="ID_477155967" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSF1: 7.34-fold Up; FDR = 4.6e-20; PValue = 1.69e-22; mean CPM = 149.8; colony stimulating factor 1 (macrophage)" ID="ID_547828063" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL11: 256-fold Up; FDR = 1e-19; PValue = 3.96e-22; mean CPM = 84.82; chemokine (C-X-C motif) ligand 11" ID="ID_60821526" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL9: 345-fold Up; FDR = 4.16e-19; PValue = 1.97e-21; mean CPM = 175.7; Macaca mulatta chemokine (C-X-C motif) ligand 9 (CXCL9), mRNA." ID="ID_1732472858" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL15: 17.3-fold Up; FDR = 2.78e-17; PValue = 1.92e-19; mean CPM = 5.103; Macaca mulatta interleukin 15 (IL15), mRNA." ID="ID_866358878" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL15RA: 19.4-fold Up; FDR = 4.04e-17; PValue = 2.89e-19; mean CPM = 5.291; interleukin 15 receptor, alpha" ID="ID_365180844" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF14: 4.66-fold Up; FDR = 2.46e-16; PValue = 2.07e-18; mean CPM = 36.12; Macaca mulatta tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) (TNFRSF14), mRNA." ID="ID_1664370547" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF10: 44.5-fold Up; FDR = 2.83e-16; PValue = 2.4e-18; mean CPM = 6.029; Tumor necrosis factor ligand superfamily member 10 isoform 1; Uncharacterized protein" ID="ID_1011493134" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL2: 24.6-fold Up; FDR = 1.83e-15; PValue = 1.69e-17; mean CPM = 668.2; Macaca mulatta chemokine (C-C motif) ligand 2 (CCL2), mRNA." ID="ID_343039260" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFRA: 2.76-fold Up; FDR = 3.93e-14; PValue = 4.67e-16; mean CPM = 492.9; platelet-derived growth factor receptor, alpha polypeptide" ID="ID_1861519563" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VEGFC: 2-fold Up; FDR = 1.3e-13; PValue = 1.76e-15; mean CPM = 238.4; Macaca mulatta vascular endothelial growth factor C (VEGFC), mRNA." ID="ID_1741775475" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL7: 9.03-fold Up; FDR = 1.39e-13; PValue = 1.9e-15; mean CPM = 5.288; interleukin 7" ID="ID_156243656" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MET: 2.57-fold Up; FDR = 3.56e-13; PValue = 5.22e-15; mean CPM = 242.4; Macaca mulatta met proto-oncogene (hepatocyte growth factor receptor) (MET), mRNA." ID="ID_162021189" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB3: 4.82-fold Down; FDR = 1.82e-12; PValue = 3.09e-14; mean CPM = 9.911; transforming growth factor, beta 3" ID="ID_1221158846" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FLT3LG: 4.17-fold Up; FDR = 3.16e-12; PValue = 5.7e-14; mean CPM = 9.659; fms-related tyrosine kinase 3 ligand" ID="ID_1814931536" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CX3CL1: 6.16-fold Up; FDR = 5.13e-12; PValue = 1e-13; mean CPM = 14.86; chemokine (C-X3-C motif) ligand 1" ID="ID_1213234886" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACVR2A: 2.11-fold Down; FDR = 1.29e-11; PValue = 2.75e-13; mean CPM = 45.81; activin A receptor, type IIA" ID="ID_164263449" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL13: 12.3-fold Up; FDR = 4.33e-10; PValue = 1.35e-11; mean CPM = 3.824; chemokine (C-C motif) ligand 13" ID="ID_1121976148" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL13RA1: 1.73-fold Up; FDR = 1.81e-09; PValue = 6.5e-11; mean CPM = 42.50; interleukin 13 receptor, alpha 1" ID="ID_1528415176" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CNTF: 4.71-fold Down; FDR = 3.15e-09; PValue = 1.21e-10; mean CPM = 2.528; ciliary neurotrophic factor" ID="ID_100845392" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL7: 8.24-fold Up; FDR = 6.67e-09; PValue = 2.75e-10; mean CPM = 8.249; chemokine (C-C motif) ligand 7" ID="ID_200290320" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGFR: 1.84-fold Up; FDR = 6.71e-09; PValue = 2.77e-10; mean CPM = 68.58; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)" ID="ID_603118827" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL6ST: 1.78-fold Up; FDR = 1.86e-08; PValue = 8.65e-10; mean CPM = 437.6; interleukin 6 signal transducer (gp130, oncostatin M receptor)" ID="ID_638866358" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL16: 3.58-fold Up; FDR = 1.19e-07; PValue = 6.74e-09; mean CPM = 6.893; chemokine (C-X-C motif) ligand 16" ID="ID_1284597006" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INHBA: 2.52-fold Down; FDR = 1.51e-07; PValue = 8.85e-09; mean CPM = 229.2; inhibin, beta A" ID="ID_1873732622" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL11RA: 1.66-fold Down; FDR = 1.74e-07; PValue = 1.02e-08; mean CPM = 33.61; interleukin 11 receptor, alpha" ID="ID_48829782" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFA: 1.92-fold Down; FDR = 2.56e-07; PValue = 1.58e-08; mean CPM = 22.99; platelet-derived growth factor alpha polypeptide" ID="ID_1480043340" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL5: 6.74-fold Up; FDR = 2.65e-07; PValue = 1.64e-08; mean CPM = 30.35; chemokine (C-C motif) ligand 5" ID="ID_1325453235" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR2: 1.74-fold Up; FDR = 1.85e-06; PValue = 1.44e-07; mean CPM = 26.05; interferon (alpha, beta and omega) receptor 2" ID="ID_1742761253" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1B: 2.24-fold Up; FDR = 2.68e-06; PValue = 2.16e-07; mean CPM = 19.44; tumor necrosis factor receptor superfamily, member 1B" ID="ID_73373145" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17B: 4.36-fold Down; FDR = 2.84e-06; PValue = 2.29e-07; mean CPM = 1.984; interleukin 17B" ID="ID_307305455" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL18R1: 3.18-fold Down; FDR = 5.89e-06; PValue = 5.19e-07; mean CPM = 3.445; interleukin 18 receptor 1" ID="ID_1282133975" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF4: 2.55-fold Down; FDR = 6.64e-06; PValue = 5.95e-07; mean CPM = 4.174; tumor necrosis factor (ligand) superfamily, member 4" ID="ID_1121114369" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="OSMR: 1.49-fold Up; FDR = 1.63e-05; PValue = 1.62e-06; mean CPM = 180.8; Uncharacterized protein" ID="ID_1076839249" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF18: 3.1-fold Down; FDR = 2.37e-05; PValue = 2.45e-06; mean CPM = 13.02; tumor necrosis factor (ligand) superfamily, member 18" ID="ID_1951187631" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL11: 6.86-fold Up; FDR = 2.69e-05; PValue = 2.82e-06; mean CPM = 4.204; chemokine (C-C motif) ligand 11" ID="ID_100505571" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1R1: 1.6-fold Up; FDR = 3.35e-05; PValue = 3.61e-06; mean CPM = 123.7; interleukin 1 receptor, type I" ID="ID_860254964" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF10D: 1.84-fold Down; FDR = 5.9e-05; PValue = 6.84e-06; mean CPM = 32.06; tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain" ID="ID_1824172401" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL6R: 3.84-fold Down; FDR = 6.68e-05; PValue = 7.89e-06; mean CPM = 4.840; interleukin 6 receptor" ID="ID_630616930" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VEGFA: 1.47-fold Up; FDR = 0.000317; PValue = 4.59e-05; mean CPM = 463.7; vascular endothelial growth factor A" ID="ID_728185382" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HGF: 1.85-fold Down; FDR = 0.000377; PValue = 5.58e-05; mean CPM = 137.4; hepatocyte growth factor (hepapoietin A; scatter factor)" ID="ID_1618484263" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40: 2.76-fold Up; FDR = 0.00039; PValue = 5.79e-05; mean CPM = 9.139; CD40 molecule, TNF receptor superfamily member 5" ID="ID_1497365340" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF9: 2.6-fold Down; FDR = 0.000438; PValue = 6.6e-05; mean CPM = 2.460; tumor necrosis factor (ligand) superfamily, member 9" ID="ID_1318399492" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LIFR: 1.59-fold Up; FDR = 0.000539; PValue = 8.35e-05; mean CPM = 35.74; leukemia inhibitory factor receptor alpha" ID="ID_1801940281" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF6B: 1.73-fold Down; FDR = 0.000702; PValue = 0.000113; mean CPM = 6.143; tumor necrosis factor receptor superfamily, member 6b, decoy" ID="ID_962153757" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCR7: 1.85-fold Up; FDR = 0.000884; PValue = 0.000146; mean CPM = 80.78; chemokine (C-X-C motif) receptor 7" ID="ID_893818316" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR1: 1.31-fold Up; FDR = 0.00151; PValue = 0.000268; mean CPM = 37.77; interferon gamma receptor 1" ID="ID_297973325" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTF1: 1.87-fold Up; FDR = 0.0019; PValue = 0.000351; mean CPM = 3.623; cardiotrophin 1" ID="ID_1613493375" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INHBB: 2.54-fold Up; FDR = 0.00193; PValue = 0.000357; mean CPM = 12.52; inhibin, beta B" ID="ID_192903003" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCR4: 4.65-fold Down; FDR = 0.00226; PValue = 0.000426; mean CPM = 2.073; chemokine (C-X-C motif) receptor 4" ID="ID_1238698934" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="OSM: 4.6-fold Down; FDR = 0.00251; PValue = 0.00048; mean CPM = 0.9104; oncostatin M" ID="ID_500439724" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF8: 2.27-fold Down; FDR = 0.00264; PValue = 0.000509; mean CPM = 2.103; tumor necrosis factor receptor superfamily, member 8" ID="ID_92739128" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSF1R: 1.92-fold Down; FDR = 0.00308; PValue = 0.000604; mean CPM = 3.242; colony stimulating factor 1 receptor" ID="ID_624648969" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL3: 3.28-fold Up; FDR = 0.00459; PValue = 0.000963; mean CPM = 50.55; chemokine (C-X-C motif) ligand 3" ID="ID_998087048" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR9: 3.89-fold Down; FDR = 0.00547; PValue = 0.00117; mean CPM = 0.9346; chemokine (C-C motif) receptor 9" ID="ID_1463666230" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL1: 2.18-fold Up; FDR = 0.00609; PValue = 0.00133; mean CPM = 45.92; chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)" ID="ID_1310834020" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL8: 3.3-fold Up; FDR = 0.00609; PValue = 0.00133; mean CPM = 1.313; chemokine (C-C motif) ligand 8" ID="ID_1741333330" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BMP2: 2.5-fold Up; FDR = 0.00836; PValue = 0.00191; mean CPM = 3.220; bone morphogenetic protein 2" ID="ID_431903836" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12A: 2.09-fold Up; FDR = 0.00924; PValue = 0.00215; mean CPM = 2.872; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)" ID="ID_1154317602" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLCF1: 1.4-fold Down; FDR = 0.00977; PValue = 0.00229; mean CPM = 21.80; cardiotrophin-like cytokine factor 1" ID="ID_1496530433" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL18: 1.5-fold Down; FDR = 0.00981; PValue = 0.0023; mean CPM = 6.489; interleukin 18 (interferon-gamma-inducing factor)" ID="ID_381128805" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR1: 1.27-fold Up; FDR = 0.0101; PValue = 0.00237; mean CPM = 82.39; Uncharacterized protein" ID="ID_458516681" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL20: 2.09-fold Up; FDR = 0.0108; PValue = 0.00256; mean CPM = 60.21; Macaca mulatta chemokine (C-C motif) ligand 20 (CCL20), mRNA." ID="ID_109837208" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INHBE: 2.28-fold Up; FDR = 0.0127; PValue = 0.00309; mean CPM = 16.73; inhibin, beta E" ID="ID_1255841913" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF12A: 1.24-fold Down; FDR = 0.0133; PValue = 0.00326; mean CPM = 478.0; tumor necrosis factor receptor superfamily, member 12A" ID="ID_559390613" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFB: 1.97-fold Down; FDR = 0.0133; PValue = 0.00326; mean CPM = 2.424; platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)" ID="ID_663629158" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EPOR: 1.56-fold Down; FDR = 0.014; PValue = 0.00347; mean CPM = 3.898; erythropoietin receptor" ID="ID_1589669794" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSF2: 2.96-fold Down; FDR = 0.0174; PValue = 0.00447; mean CPM = 73.98; colony stimulating factor 2 (granulocyte-macrophage)" ID="ID_155253163" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRLF2: 2.92-fold Down; FDR = 0.0202; PValue = 0.00531; mean CPM = 1.758; cytokine receptor-like factor 2" ID="ID_1522260896" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL8: 2.33-fold Up; FDR = 0.0209; PValue = 0.00552; mean CPM = 2326; interleukin 8" ID="ID_1284612829" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL20RA: 2.25-fold Up; FDR = 0.0255; PValue = 0.00695; mean CPM = 1.386; interleukin 20 receptor, alpha" ID="ID_151281727" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR2: 1.23-fold Up; FDR = 0.0258; PValue = 0.00707; mean CPM = 46.52; interferon gamma receptor 2 (interferon gamma transducer 1)" ID="ID_1380252052" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL18RAP: 2.95-fold Down; FDR = 0.0275; PValue = 0.00761; mean CPM = 1.220; interleukin 18 receptor accessory protein" ID="ID_1184980749" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KDR: 2.01-fold Up; FDR = 0.0328; PValue = 0.00936; mean CPM = 2.053; kinase insert domain receptor (a type III receptor tyrosine kinase)" ID="ID_1577884583" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR7: 1.48-fold Down; FDR = 0.0357; PValue = 0.0103; mean CPM = 13.37; chemokine (C-C motif) receptor 7" ID="ID_1627945626" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFBR1: 1.2-fold Up; FDR = 0.037; PValue = 0.0108; mean CPM = 90.92; transforming growth factor, beta receptor 1" ID="ID_162255534" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF11: 1.8-fold Up; FDR = 0.039; PValue = 0.0115; mean CPM = 2.535; tumor necrosis factor (ligand) superfamily, member 11" ID="ID_664626537" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1RAP: 1.35-fold Up; FDR = 0.0392; PValue = 0.0116; mean CPM = 10.66; interleukin 1 receptor accessory protein" ID="ID_188589640" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LEP: 1.67-fold Down; FDR = 0.0401; PValue = 0.0118; mean CPM = 63.70; leptin" ID="ID_1049760325" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACVR1: 1.19-fold Up; FDR = 0.0473; PValue = 0.0144; mean CPM = 50.55; activin A receptor, type I" ID="ID_236350955" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TPO: 2.96-fold Down; FDR = 0.0533; PValue = 0.0166; mean CPM = 1.110; thyroid peroxidase" ID="ID_1230939614" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL28: 2.67-fold Up; FDR = 0.0616; PValue = 0.0197; mean CPM = 1.020; chemokine (C-C motif) ligand 28" ID="ID_1611435450" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFBR2: 1.19-fold Up; FDR = 0.0643; PValue = 0.0208; mean CPM = 350.8; transforming growth factor, beta receptor II (70/80kDa)" ID="ID_1225079107" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL3: 2.04-fold Down; FDR = 0.067; PValue = 0.0218; mean CPM = 3.575; chemokine (C-C motif) ligand 3" ID="ID_1881996721" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL7R: 1.76-fold Down; FDR = 0.0698; PValue = 0.0229; mean CPM = 3.067; interleukin 7 receptor" ID="ID_812130401" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSF3: 2.55-fold Up; FDR = 0.0701; PValue = 0.023; mean CPM = 72.12; colony stimulating factor 3 (granulocyte)" ID="ID_81617669" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCR5: 2.19-fold Down; FDR = 0.0766; PValue = 0.0256; mean CPM = 1.341; chemokine (C-X-C motif) receptor 5" ID="ID_1948023212" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL28RA: 2.43-fold Down; FDR = 0.115; PValue = 0.0414; mean CPM = 0.9001; interleukin 28 receptor, alpha (interferon, lambda receptor)" ID="ID_298500664" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF11B: 1.31-fold Down; FDR = 0.121; PValue = 0.0439; mean CPM = 722.1; Uncharacterized protein" ID="ID_1459518217" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17RA: 1.16-fold Up; FDR = 0.121; PValue = 0.0443; mean CPM = 48.31; interleukin 17 receptor A" ID="ID_1725612739" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLEKHO2: 1.16-fold Down; FDR = 0.135; PValue = 0.0507; mean CPM = 46.02; pleckstrin homology domain containing, family O member 2" ID="ID_918258126" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACVR2B: 1.37-fold Up; FDR = 0.16; PValue = 0.0621; mean CPM = 3.121; activin A receptor, type IIB" ID="ID_861307405" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BMPR1B: 1.73-fold Down; FDR = 0.18; PValue = 0.0718; mean CPM = 1.275; bone morphogenetic protein receptor, type IB" ID="ID_1381318607" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL6: 1.5-fold Down; FDR = 0.2; PValue = 0.082; mean CPM = 258.8; chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)" ID="ID_493613838" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KITLG: 1.31-fold Up; FDR = 0.209; PValue = 0.0867; mean CPM = 5.766; KIT ligand" ID="ID_1149682585" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1A: 1.11-fold Up; FDR = 0.297; PValue = 0.134; mean CPM = 134.7; tumor necrosis factor receptor superfamily, member 1A" ID="ID_613497717" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12RB2: 1.42-fold Down; FDR = 0.299; PValue = 0.135; mean CPM = 1.728; interleukin 12 receptor, beta 2" ID="ID_505429534" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1A: 1.5-fold Up; FDR = 0.315; PValue = 0.144; mean CPM = 155.4; interleukin 1, alpha" ID="ID_914641399" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF10B: 1.13-fold Down; FDR = 0.343; PValue = 0.16; mean CPM = 40.59; tumor necrosis factor receptor superfamily, member 10b" ID="ID_558262238" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD70: 1.37-fold Up; FDR = 0.345; PValue = 0.161; mean CPM = 11.18; Uncharacterized protein" ID="ID_386094383" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL23A: 1.39-fold Up; FDR = 0.348; PValue = 0.163; mean CPM = 4.542; interleukin 23, alpha subunit p19" ID="ID_1308973986" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GHR: 1.23-fold Up; FDR = 0.369; PValue = 0.175; mean CPM = 6.312; growth hormone receptor" ID="ID_1777921193" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EPO: 1.77-fold Up; FDR = 0.39; PValue = 0.188; mean CPM = 0.9174; Macaca mulatta erythropoietin (EPO), mRNA." ID="ID_1172322371" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MPL: 1.3-fold Down; FDR = 0.411; PValue = 0.201; mean CPM = 2.108; myeloproliferative leukemia virus oncogene" ID="ID_85402331" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF18: 1.79-fold Down; FDR = 0.411; PValue = 0.201; mean CPM = 0.9222; tumor necrosis factor receptor superfamily, member 18" ID="ID_1805232057" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL26: 1.74-fold Down; FDR = 0.423; PValue = 0.208; mean CPM = 0.8756; chemokine (C-C motif) ligand 26" ID="ID_482380206" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CNTFR: 1.67-fold Down; FDR = 0.435; PValue = 0.216; mean CPM = 1.033; Uncharacterized protein" ID="ID_19130939" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL19: 1.65-fold Down; FDR = 0.455; PValue = 0.228; mean CPM = 0.9514; interleukin 19" ID="ID_515427884" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR5: 1.56-fold Down; FDR = 0.487; PValue = 0.249; mean CPM = 1.064; chemokine (C-C motif) receptor 5" ID="ID_1958005898" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL12: 1.27-fold Down; FDR = 0.488; PValue = 0.251; mean CPM = 4.383; chemokine (C-X-C motif) ligand 12" ID="ID_1207210110" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LEPR: 1.52-fold Down; FDR = 0.489; PValue = 0.251; mean CPM = 1.051; leptin receptor" ID="ID_807938371" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VEGFB: 1.1-fold Down; FDR = 0.512; PValue = 0.267; mean CPM = 16.03; vascular endothelial growth factor B" ID="ID_584149269" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL10RA: 1.55-fold Down; FDR = 0.516; PValue = 0.269; mean CPM = 0.9545; interleukin 10 receptor, alpha" ID="ID_307164711" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL21R: 1.56-fold Down; FDR = 0.534; PValue = 0.282; mean CPM = 1.021; interleukin 21 receptor" ID="ID_1008366470" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD27: 1.52-fold Down; FDR = 0.547; PValue = 0.292; mean CPM = 1.004; CD27 molecule" ID="ID_1642830644" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL24: 1.37-fold Down; FDR = 0.563; PValue = 0.303; mean CPM = 26.16; interleukin 24" ID="ID_640684844" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AMHR2: 1.22-fold Down; FDR = 0.625; PValue = 0.348; mean CPM = 2.066; anti-Mullerian hormone receptor, type II" ID="ID_1448639456" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1R2: 1.37-fold Up; FDR = 0.628; PValue = 0.35; mean CPM = 1.132; interleukin 1 receptor, type II" ID="ID_535923536" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL9R: 2.21-fold Down; FDR = 0.63; PValue = 0.352; mean CPM = 0.8661; interleukin 9 receptor" ID="ID_824745618" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNE: 1.18-fold Up; FDR = 0.646; PValue = 0.364; mean CPM = 2.614; interferon, epsilon" ID="ID_1178338619" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_192742168" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000001259: 1.31-fold Down; FDR = 0.663; PValue = 0.378; mean CPM = 3.829; Uncharacterized protein" ID="ID_607043492" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF11A: 1.4-fold Down; FDR = 0.676; PValue = 0.388; mean CPM = 0.9723; tumor necrosis factor receptor superfamily, member 11a, NFKB activator" ID="ID_1654313486" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CX3CR1: 2.01-fold Up; FDR = 0.678; PValue = 0.389; mean CPM = 0.8149; chemokine (C-X3-C motif) receptor 1" ID="ID_108319559" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LTBR: 1.06-fold Down; FDR = 0.683; PValue = 0.394; mean CPM = 91.13; lymphotoxin beta receptor (TNFR superfamily, member 3)" ID="ID_139068111" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LIF: 1.07-fold Down; FDR = 0.702; PValue = 0.409; mean CPM = 148.6; leukemia inhibitory factor (cholinergic differentiation factor)" ID="ID_820424583" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12RB1: 1.39-fold Up; FDR = 0.703; PValue = 0.41; mean CPM = 0.9665; interleukin 12 receptor, beta 1" ID="ID_1222647461" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL11: 1.13-fold Up; FDR = 0.715; PValue = 0.42; mean CPM = 128.8; interleukin 11" ID="ID_1574764043" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNB1: 1.79-fold Up; FDR = 0.731; PValue = 0.433; mean CPM = 0.8526; interferon, beta 1, fibroblast" ID="ID_503250638" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF10A: 1.06-fold Down; FDR = 0.732; PValue = 0.434; mean CPM = 42.75; tumor necrosis factor receptor superfamily, member 10a" ID="ID_889580401" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF4: 1.36-fold Down; FDR = 0.743; PValue = 0.444; mean CPM = 0.8892; tumor necrosis factor receptor superfamily, member 4" ID="ID_1388110332" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17RB: 1.24-fold Down; FDR = 0.752; PValue = 0.452; mean CPM = 1.299; interleukin 17 receptor B" ID="ID_219885398" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL1: 1.56-fold Up; FDR = 0.772; PValue = 0.47; mean CPM = 0.8202; chemokine (C-C motif) ligand 1" ID="ID_1300489637" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL4R: 1.05-fold Down; FDR = 0.803; PValue = 0.499; mean CPM = 193.5; interleukin 4 receptor" ID="ID_1422657502" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR6: 1.51-fold Down; FDR = 0.807; PValue = 0.504; mean CPM = 0.8112; Macaca mulatta chemokine (C-C motif) receptor 6 (CCR6), mRNA." ID="ID_1969847639" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA6: 1.41-fold Down; FDR = 0.807; PValue = 0.504; mean CPM = 0.8019; interferon, alpha 6" ID="ID_914619003" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL27: 1.17-fold Up; FDR = 0.817; PValue = 0.515; mean CPM = 1.645; chemokine (C-C motif) ligand 27" ID="ID_1728637657" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR2: 1.51-fold Up; FDR = 0.823; PValue = 0.523; mean CPM = 0.8333; chemokine (C-C motif) receptor 2" ID="ID_1172968091" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR4: 1.74-fold Up; FDR = 0.831; PValue = 0.533; mean CPM = 0.8536; chemokine (C-C motif) receptor 4" ID="ID_732683165" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL28B: 1.53-fold Down; FDR = 0.836; PValue = 0.541; mean CPM = 0.8237; interleukin 28B (interferon, lambda 3)" ID="ID_721608531" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XCL1: 1.39-fold Up; FDR = 0.838; PValue = 0.544; mean CPM = 0.8038; chemokine (C motif) ligand 1" ID="ID_1612163028" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL22RA1: 1.26-fold Up; FDR = 0.846; PValue = 0.555; mean CPM = 0.9674; interleukin 22 receptor, alpha 1" ID="ID_1999651325" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FLT1: 1.08-fold Down; FDR = 0.849; PValue = 0.558; mean CPM = 28.21; fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)" ID="ID_1734397445" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL16: 1.27-fold Up; FDR = 0.865; PValue = 0.581; mean CPM = 0.7999; chemokine (C-C motif) ligand 16" ID="ID_1539653541" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_1230684496" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL29: 1.38-fold Down; FDR = 0.898; PValue = 0.624; mean CPM = 0.8355; interleukin 29 (interferon, lambda 1)" ID="ID_1062941644" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL22RA2: 1.2-fold Down; FDR = 0.899; PValue = 0.629; mean CPM = 0.7954; interleukin 22 receptor, alpha 2" ID="ID_1703927928" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_280318121" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL25: 1.24-fold Down; FDR = 0.899; PValue = 0.631; mean CPM = 0.7976; interleukin 25" ID="ID_1566210342" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XCL1: 1.24-fold Down; FDR = 0.899; PValue = 0.635; mean CPM = 0.7954; Macaca mulatta chemokine (C motif) ligand 1 (XCL1), mRNA." ID="ID_402173863" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XCL1: 1.24-fold Down; FDR = 0.899; PValue = 0.635; mean CPM = 0.7954; Macaca mulatta chemokine (C motif) ligand 1 (XCL1), mRNA." ID="ID_1848990902" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BMPR1A: 1.04-fold Up; FDR = 0.903; PValue = 0.641; mean CPM = 36.13; bone morphogenetic protein receptor, type IA" ID="ID_1873149059" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF14: 1.16-fold Down; FDR = 0.903; PValue = 0.645; mean CPM = 0.7940; tumor necrosis factor (ligand) superfamily, member 14" ID="ID_590826308" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB2: 1.05-fold Down; FDR = 0.903; PValue = 0.655; mean CPM = 110.8; transforming growth factor, beta 2" ID="ID_452322836" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR3: 1.43-fold Up; FDR = 0.906; PValue = 0.665; mean CPM = 0.8397; chemokine (C-C motif) receptor 3" ID="ID_1605246358" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSF2RA: 1.19-fold Up; FDR = 0.906; PValue = 0.666; mean CPM = 0.9897; colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)" ID="ID_903946589" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA13: 1.13-fold Up; FDR = 0.908; PValue = 0.677; mean CPM = 0.7960; interferon, alpha 13" ID="ID_1961109437" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FLT4: 1.19-fold Down; FDR = 0.909; PValue = 0.689; mean CPM = 0.8780; fms-related tyrosine kinase 4" ID="ID_506353192" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL14: 1.15-fold Up; FDR = 0.909; PValue = 0.69; mean CPM = 0.7938; chemokine (C-C motif) ligand 14" ID="ID_1906185322" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INHBC: 1.3-fold Down; FDR = 0.911; PValue = 0.698; mean CPM = 0.8207; inhibin, beta C" ID="ID_1115449375" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF9: 1.28-fold Down; FDR = 0.911; PValue = 0.7; mean CPM = 0.8318; tumor necrosis factor receptor superfamily, member 9" ID="ID_1571355643" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA8: 1.13-fold Down; FDR = 0.911; PValue = 0.702; mean CPM = 0.7910; interferon, alpha 8" ID="ID_240853967" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL9: 1.14-fold Up; FDR = 0.911; PValue = 0.705; mean CPM = 0.7910; interleukin 9" ID="ID_748061313" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17A: 1.12-fold Up; FDR = 0.911; PValue = 0.706; mean CPM = 0.7895; interleukin 17A" ID="ID_530746574" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AMH: 1.35-fold Down; FDR = 0.914; PValue = 0.71; mean CPM = 0.8126; anti-Mullerian hormone" ID="ID_609180943" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR1: 1.24-fold Up; FDR = 0.915; PValue = 0.714; mean CPM = 0.8590; Macaca mulatta chemokine (C-C motif) receptor 1 (CCR1), mRNA." ID="ID_78989497" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSF3R: 1.13-fold Down; FDR = 0.921; PValue = 0.723; mean CPM = 0.9331; colony stimulating factor 3 receptor (granulocyte)" ID="ID_1540294854" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GDF5: 1.16-fold Down; FDR = 0.922; PValue = 0.726; mean CPM = 0.9185; growth differentiation factor 5" ID="ID_398627454" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL22: 1.33-fold Down; FDR = 0.928; PValue = 0.735; mean CPM = 0.8193; interleukin 22" ID="ID_1868973353" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL4: 1.27-fold Down; FDR = 0.933; PValue = 0.745; mean CPM = 0.8077; interleukin 4" ID="ID_354003426" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB1: 1.02-fold Down; FDR = 0.936; PValue = 0.749; mean CPM = 62.61; transforming growth factor, beta 1" ID="ID_1158991749" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FASLG: 1.2-fold Down; FDR = 0.941; PValue = 0.757; mean CPM = 0.8088; Fas ligand (TNF superfamily, member 6)" ID="ID_1190395125" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2RA: 1.08-fold Up; FDR = 0.945; PValue = 0.766; mean CPM = 0.8493; interleukin 2 receptor, alpha" ID="ID_1588000291" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF8: 1.2-fold Up; FDR = 0.947; PValue = 0.77; mean CPM = 0.8596; tumor necrosis factor (ligand) superfamily, member 8" ID="ID_1009040315" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FLT3: 1.48-fold Down; FDR = 0.948; PValue = 0.77; mean CPM = 0.8603; fms-related tyrosine kinase 3" ID="ID_583346254" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL21: 1.04-fold Up; FDR = 0.948; PValue = 0.773; mean CPM = 0.8164; interleukin 21" ID="ID_1886833118" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL20: 1.22-fold Up; FDR = 0.951; PValue = 0.779; mean CPM = 0.8273; interleukin 20" ID="ID_774635258" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF17: 1.08-fold Down; FDR = 0.954; PValue = 0.783; mean CPM = 1.418; tumor necrosis factor receptor superfamily, member 17" ID="ID_542977010" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF13B: 1.06-fold Up; FDR = 0.954; PValue = 0.784; mean CPM = 0.8104; tumor necrosis factor receptor superfamily, member 13B" ID="ID_1973912486" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL5RA: 1.1-fold Up; FDR = 0.958; PValue = 0.791; mean CPM = 0.8108; interleukin 5 receptor, alpha" ID="ID_210641873" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA14: 1.22-fold Up; FDR = 0.965; PValue = 0.802; mean CPM = 0.8654; interferon, alpha 14" ID="ID_64372731" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL13: 1.05-fold Up; FDR = 0.967; PValue = 0.805; mean CPM = 0.8212; interleukin 13" ID="ID_33420970" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XCR1: 1.09-fold Up; FDR = 0.971; PValue = 0.812; mean CPM = 0.8071; chemokine (C motif) receptor 1" ID="ID_1655400439" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL21: 1.09-fold Down; FDR = 0.972; PValue = 0.813; mean CPM = 1.083; chemokine (C-C motif) ligand 21" ID="ID_1542988497" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA4: 1.28-fold Down; FDR = 0.983; PValue = 0.829; mean CPM = 0.8584; interferon, alpha 4" ID="ID_1723093766" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12B: 1.07-fold Up; FDR = 0.983; PValue = 0.831; mean CPM = 0.8197; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)" ID="ID_719922670" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR8: 1.15-fold Down; FDR = 0.999; PValue = 0.857; mean CPM = 0.8181; chemokine (C-C motif) receptor 8" ID="ID_856968933" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL5: 1.05-fold Down; FDR = 1; PValue = 0.862; mean CPM = 1.367; interleukin 5 (colony-stimulating factor, eosinophil)" ID="ID_499844924" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL25: 1.05-fold Down; FDR = 1; PValue = 0.872; mean CPM = 1.770; chemokine (C-C motif) ligand 25" ID="ID_106816874" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL22: 1.13-fold Down; FDR = 1; PValue = 0.872; mean CPM = 0.8179; chemokine (C-C motif) ligand 22" ID="ID_1698361544" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFRB: 1.01-fold Up; FDR = 1; PValue = 0.883; mean CPM = 391.1; platelet-derived growth factor receptor, beta polypeptide" ID="ID_731026102" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGF: 1.06-fold Down; FDR = 1; PValue = 0.885; mean CPM = 0.8917; epidermal growth factor" ID="ID_1833295101" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRLR: 1.06-fold Down; FDR = 1; PValue = 0.889; mean CPM = 1.017; prolactin receptor" ID="ID_613878003" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL3: 1.17-fold Down; FDR = 1; PValue = 0.9; mean CPM = 0.8325; Macaca mulatta interleukin 3 (colony-stimulating factor, multiple) (IL3), mRNA." ID="ID_1775971752" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR10: 1.01-fold Down; FDR = 1; PValue = 0.929; mean CPM = 4.275; chemokine (C-C motif) receptor 10" ID="ID_1186340889" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCR2: 1.14-fold Up; FDR = 1; PValue = 0.929; mean CPM = 0.8384; chemokine (C-X-C motif) receptor 2" ID="ID_1580865633" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EDA: 1.15-fold Down; FDR = 1; PValue = 0.934; mean CPM = 0.8169; ectodysplasin A" ID="ID_1661003346" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LTB: 1.01-fold Up; FDR = 1; PValue = 0.935; mean CPM = 0.8459; Lymphotoxin-beta (LT-beta)(Tumor necrosis factor C)(TNF-C)(Tumor necrosis factor ligand superfamily member 3)" ID="ID_1114274109" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000006973: 1.09-fold Down; FDR = 1; PValue = 0.938; mean CPM = 0.8165; Uncharacterized protein" ID="ID_69894022" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCR3: 1.03-fold Up; FDR = 1; PValue = 0.943; mean CPM = 0.9843; chemokine (C-X-C motif) receptor 3" ID="ID_165053078" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPBP: 1.16-fold Up; FDR = 1; PValue = 0.95; mean CPM = 0.8406; pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)" ID="ID_1924105091" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL23: 1.03-fold Down; FDR = 1; PValue = 0.963; mean CPM = 0.9423; Macaca mulatta chemokine (C-C motif) ligand 23 (CCL23), mRNA." ID="ID_914296372" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL10: 1.21-fold Down; FDR = 1; PValue = 0.964; mean CPM = 0.8614; interleukin 10" ID="ID_1406159015" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BMPR2: No Change; FDR = 1; PValue = 0.974; mean CPM = 136.9; Bone morphogenetic protein receptor type-2; Uncharacterized protein" ID="ID_10173407" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40LG: 1.01-fold Down; FDR = 1; PValue = 0.982; mean CPM = 0.8653; CD40 ligand" ID="ID_568188193" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL17: 1.01-fold Up; FDR = 1; PValue = 0.993; mean CPM = 0.8083; Macaca mulatta chemokine (C-C motif) ligand 17 (CCL17), mRNA." ID="ID_84057410" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000007111: 1.12-fold Down; FDR = 1; PValue = 0.993; mean CPM = 0.8245; Uncharacterized protein" ID="ID_82380232" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL23R: 1.05-fold Down; FDR = 1; PValue = 0.994; mean CPM = 0.7958; interleukin 23 receptor" ID="ID_265948965" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BMP7: 1.01-fold Up; FDR = 1; PValue = 0.994; mean CPM = 0.8010; bone morphogenetic protein 7" ID="ID_1512668589" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FIGF: 1.07-fold Up; FDR = 1; PValue = 0.995; mean CPM = 0.8037; c-fos induced growth factor (vascular endothelial growth factor D)" ID="ID_1458338052" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2: 1.03-fold Up; FDR = 1; PValue = 0.998; mean CPM = 0.7974; interleukin 2" ID="ID_1359802104" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA1: No Change; FDR = 1; PValue = 0.998; mean CPM = 0.8014; interferon, alpha 1" ID="ID_1981991473" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL24: 1.01-fold Up; FDR = 1; PValue = 0.999; mean CPM = 0.8072; Uncharacterized protein" ID="ID_1693730276" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACVR1B: No Change; FDR = 1; PValue = 0.999; mean CPM = 11.63; activin A receptor, type IB" ID="ID_974185002" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNK: No Change; FDR = 1; PValue = 1; mean CPM = 0.7868; interferon, kappa" ID="ID_351944606" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL13: No Change; FDR = 1; PValue = 1; mean CPM = 0.7851; chemokine (C-X-C motif) ligand 13" ID="ID_1847584588" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCR1: No Change; FDR = 1; PValue = 1; mean CPM = 0.7827; chemokine (C-X-C motif) receptor 1" ID="ID_1547899830" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNW1: No Change; FDR = 1; PValue = 1; mean CPM = 0.7851; interferon, omega 1" ID="ID_830029112" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Hepatitis B: Activated, FDR = 0.00103, FWER = 0.0084, PValue = 5.79e-05" ID="ID_167711652" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TLR2: 8.94-fold Up; FDR = 6.97e-23; PValue = 1.25e-25; mean CPM = 18.41; toll-like receptor 2" ID="ID_1568212593" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFIH1: 14.7-fold Up; FDR = 8.74e-23; PValue = 1.68e-25; mean CPM = 49.84; interferon induced with helicase C domain 1" ID="ID_189558593" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR3: 10.3-fold Up; FDR = 1.95e-21; PValue = 5.6e-24; mean CPM = 35.70; toll-like receptor 3" ID="ID_1167269539" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT2: 2.67-fold Up; FDR = 8.02e-19; PValue = 4.03e-21; mean CPM = 185.6; signal transducer and activator of transcription 2, 113kDa" ID="ID_105155359" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1293980099" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DDX58: 6.4-fold Up; FDR = 5.12e-18; PValue = 3.06e-20; mean CPM = 86.14; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58" ID="ID_444212704" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF7: 14.8-fold Up; FDR = 7.66e-18; PValue = 4.82e-20; mean CPM = 11.54; Macaca mulatta interferon regulatory factor 7 (IRF7), mRNA." ID="ID_842846014" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_1143104831" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5A: 2.28-fold Up; FDR = 6.87e-14; PValue = 8.58e-16; mean CPM = 21.55; signal transducer and activator of transcription 5A" ID="ID_1551729024" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB3: 4.82-fold Down; FDR = 1.82e-12; PValue = 3.09e-14; mean CPM = 9.911; transforming growth factor, beta 3" ID="ID_328425408" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3L2: 2.11-fold Down; FDR = 5.05e-12; PValue = 9.78e-14; mean CPM = 64.33; cAMP responsive element binding protein 3-like 2" ID="ID_636699338" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC4: 1.85-fold Down; FDR = 1.13e-11; PValue = 2.37e-13; mean CPM = 51.58; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4" ID="ID_1176607482" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_1801589604" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3L1: 1.99-fold Down; FDR = 1.52e-09; PValue = 5.36e-11; mean CPM = 211.4; cAMP responsive element binding protein 3-like 1" ID="ID_1030591215" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAVS: 1.92-fold Down; FDR = 2.7e-09; PValue = 1.02e-10; mean CPM = 29.16; mitochondrial antiviral signaling protein" ID="ID_1578493290" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR4: 3.45-fold Up; FDR = 3.1e-09; PValue = 1.19e-10; mean CPM = 7.456; Macaca mulatta toll-like receptor 4 (TLR4), mRNA." ID="ID_1299176614" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1B: 1.64-fold Up; FDR = 1.22e-08; PValue = 5.39e-10; mean CPM = 32.96; Cyclin-dependent kinase inhibitor 1B; Uncharacterized protein" ID="ID_1497616251" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP6AP1: 1.65-fold Down; FDR = 1.8e-08; PValue = 8.33e-10; mean CPM = 82.41; ATPase, H+ transporting, lysosomal accessory protein 1" ID="ID_1756576963" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1003538889" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RB1: 1.65-fold Up; FDR = 6.01e-08; PValue = 3.2e-09; mean CPM = 59.24; retinoblastoma 1" ID="ID_710918776" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2B: 3.54-fold Up; FDR = 1.24e-07; PValue = 7.07e-09; mean CPM = 5.971; PTK2B protein tyrosine kinase 2 beta" ID="ID_1943390230" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_1813809130" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1252022106" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_836848280" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_144287452" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_428345616" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_772954811" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_63299293" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT4: 1.79-fold Up; FDR = 2.3e-05; PValue = 2.36e-06; mean CPM = 26.79; signal transducer and activator of transcription 4" ID="ID_7551224" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VDAC3: 1.37-fold Up; FDR = 8.35e-05; PValue = 1.01e-05; mean CPM = 104.8; voltage-dependent anion channel 3" ID="ID_635067431" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB5: 2.1-fold Down; FDR = 0.000248; PValue = 3.48e-05; mean CPM = 4.269; cAMP responsive element binding protein 5" ID="ID_1870953011" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC2: 4.03-fold Down; FDR = 0.000346; PValue = 5.06e-05; mean CPM = 1.347; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2" ID="ID_1700576298" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF2: 1.34-fold Up; FDR = 0.000403; PValue = 6.01e-05; mean CPM = 39.83; activating transcription factor 2" ID="ID_1276333168" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_1230909530" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD3: 1.38-fold Up; FDR = 0.000573; PValue = 8.94e-05; mean CPM = 114.9; SMAD family member 3" ID="ID_1772631396" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAD: 1.36-fold Down; FDR = 0.000605; PValue = 9.52e-05; mean CPM = 48.46; BCL2-associated agonist of cell death" ID="ID_1732890774" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGR2: 1.8-fold Down; FDR = 0.00121; PValue = 0.000209; mean CPM = 15.95; early growth response 2" ID="ID_633983104" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP9: 4.49-fold Down; FDR = 0.00222; PValue = 0.000419; mean CPM = 6.597; matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)" ID="ID_197431000" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF4: 1.29-fold Up; FDR = 0.00296; PValue = 0.000579; mean CPM = 618.7; activating transcription factor 4 (tax-responsive enhancer element B67)" ID="ID_431614991" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBK1: 1.3-fold Up; FDR = 0.00337; PValue = 0.000674; mean CPM = 30.46; TANK-binding kinase 1" ID="ID_488393623" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PCNA: 1.34-fold Up; FDR = 0.00398; PValue = 0.000816; mean CPM = 112.1; PCNA antisense RNA (non-protein coding)" ID="ID_342476399" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_690498373" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_743159940" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR1: 1.27-fold Up; FDR = 0.0101; PValue = 0.00237; mean CPM = 82.39; Uncharacterized protein" ID="ID_1979504432" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HBXIP: 1.24-fold Up; FDR = 0.0155; PValue = 0.00392; mean CPM = 74.39; Uncharacterized protein" ID="ID_642315933" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP10: 1.81-fold Up; FDR = 0.0175; PValue = 0.0045; mean CPM = 2.876; caspase 10, apoptosis-related cysteine peptidase" ID="ID_1426889681" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK2: 1.23-fold Down; FDR = 0.0194; PValue = 0.00507; mean CPM = 36.76; cyclin-dependent kinase 2" ID="ID_500102785" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_941820575" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL8: 2.33-fold Up; FDR = 0.0209; PValue = 0.00552; mean CPM = 2326; interleukin 8" ID="ID_588770363" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1403696890" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_1119535150" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB1: 1.21-fold Up; FDR = 0.0313; PValue = 0.00884; mean CPM = 36.07; cAMP responsive element binding protein 1" ID="ID_3242339" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGR3: 2.19-fold Down; FDR = 0.0355; PValue = 0.0103; mean CPM = 3.291; early growth response 3" ID="ID_619238678" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFBR1: 1.2-fold Up; FDR = 0.037; PValue = 0.0108; mean CPM = 90.92; transforming growth factor, beta receptor 1" ID="ID_1722003057" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_410010324" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KRAS: 1.35-fold Down; FDR = 0.0401; PValue = 0.0119; mean CPM = 13.10; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog" ID="ID_348124766" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="E2F1: 1.44-fold Down; FDR = 0.0425; PValue = 0.0127; mean CPM = 8.857; E2F transcription factor 1" ID="ID_631629833" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NRAS: 1.2-fold Down; FDR = 0.0546; PValue = 0.017; mean CPM = 32.39; neuroblastoma RAS viral (v-ras) oncogene homolog" ID="ID_1616939094" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_918238768" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_52214813" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT6: 1.18-fold Up; FDR = 0.0727; PValue = 0.024; mean CPM = 217.5; signal transducer and activator of transcription 6, interleukin-4 induced" ID="ID_1291195101" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FADD: 1.18-fold Down; FDR = 0.0936; PValue = 0.0324; mean CPM = 30.89; Uncharacterized protein" ID="ID_422114302" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_600759013" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3L4: 1.3-fold Down; FDR = 0.0961; PValue = 0.0334; mean CPM = 6.034; cAMP responsive element binding protein 3-like 4" ID="ID_1505679729" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_171244221" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3: 1.15-fold Up; FDR = 0.128; PValue = 0.0472; mean CPM = 167.9; cAMP responsive element binding protein 3" ID="ID_1281025563" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_778786853" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC5: 1.51-fold Down; FDR = 0.134; PValue = 0.0501; mean CPM = 18.55; Baculoviral IAP repeat-containing protein 5 isoform 1; Uncharacterized protein" ID="ID_1050762954" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1690718912" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTEN: 1.14-fold Up; FDR = 0.166; PValue = 0.065; mean CPM = 89.60; phosphatase and tensin homolog" ID="ID_890584909" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_516281301" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000039103: 1.67-fold Down; FDR = 0.221; PValue = 0.0927; mean CPM = 1.310; Uncharacterized protein" ID="ID_871983399" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1A: 1.16-fold Down; FDR = 0.28; PValue = 0.124; mean CPM = 363.2; Cyclin-dependent kinase inhibitor 1; Uncharacterized protein" ID="ID_1215629777" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_1143055198" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK6: 1.18-fold Down; FDR = 0.301; PValue = 0.136; mean CPM = 26.51; cyclin-dependent kinase 6" ID="ID_187648727" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EP300: 1.11-fold Up; FDR = 0.312; PValue = 0.142; mean CPM = 162.8; E1A binding protein p300" ID="ID_42339890" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_639869015" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP53: 1.11-fold Down; FDR = 0.364; PValue = 0.172; mean CPM = 33.25; tumor protein p53" ID="ID_302833184" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_117100191" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2: 1.48-fold Up; FDR = 0.384; PValue = 0.184; mean CPM = 1.344; Uncharacterized protein" ID="ID_474427378" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TICAM1: 1.11-fold Down; FDR = 0.398; PValue = 0.192; mean CPM = 26.73; toll-like receptor adaptor molecule 1" ID="ID_611074610" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_966398711" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC1: 1.11-fold Down; FDR = 0.457; PValue = 0.23; mean CPM = 19.06; Uncharacterized protein" ID="ID_1304042432" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DDX3X: 1.09-fold Up; FDR = 0.478; PValue = 0.244; mean CPM = 344.2; DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked" ID="ID_1864604472" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_496321578" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCG: 1.47-fold Down; FDR = 0.609; PValue = 0.336; mean CPM = 0.9297; protein kinase C, gamma" ID="ID_569500485" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCB: 1.86-fold Up; FDR = 0.727; PValue = 0.43; mean CPM = 0.8705; protein kinase C, beta" ID="ID_652245074" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNB1: 1.79-fold Up; FDR = 0.731; PValue = 0.433; mean CPM = 0.8526; interferon, beta 1, fibroblast" ID="ID_1359549470" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="E2F3: 1.08-fold Up; FDR = 0.751; PValue = 0.452; mean CPM = 11.79; E2F transcription factor 3" ID="ID_133775268" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_193704588" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREBL1: 1.05-fold Down; FDR = 0.794; PValue = 0.491; mean CPM = 64.18; activating transcription factor 6 beta" ID="ID_60633341" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA6: 1.41-fold Down; FDR = 0.807; PValue = 0.504; mean CPM = 0.8019; interferon, alpha 6" ID="ID_1197357252" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAX: 1.05-fold Up; FDR = 0.809; PValue = 0.506; mean CPM = 162.4; Uncharacterized protein" ID="ID_1206402552" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APAF1: 1.05-fold Down; FDR = 0.837; PValue = 0.543; mean CPM = 32.11; apoptotic peptidase activating factor 1" ID="ID_1986590824" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TIRAP: 1.07-fold Up; FDR = 0.841; PValue = 0.548; mean CPM = 8.693; Macaca mulatta toll-interleukin 1 receptor (TIR) domain containing adaptor protein (TIRAP), mRNA." ID="ID_695848999" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYCS: 1.05-fold Up; FDR = 0.854; PValue = 0.565; mean CPM = 93.43; cytochrome c, somatic" ID="ID_1176135990" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1770083082" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000040219: 1.08-fold Up; FDR = 0.86; PValue = 0.575; mean CPM = 8.818; Uncharacterized protein" ID="ID_774315941" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_709301445" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_790290782" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK4: 1.04-fold Up; FDR = 0.899; PValue = 0.626; mean CPM = 65.45; cyclin-dependent kinase 4" ID="ID_508865795" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB2: 1.05-fold Down; FDR = 0.903; PValue = 0.655; mean CPM = 110.8; transforming growth factor, beta 2" ID="ID_1857393610" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD4: 1.03-fold Down; FDR = 0.906; PValue = 0.666; mean CPM = 43.02; SMAD family member 4" ID="ID_716024090" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA13: 1.13-fold Up; FDR = 0.908; PValue = 0.677; mean CPM = 0.7960; interferon, alpha 13" ID="ID_376799650" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3L3: 1.4-fold Down; FDR = 0.908; PValue = 0.679; mean CPM = 0.8407; cAMP responsive element binding protein 3-like 3" ID="ID_415076164" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA8: 1.13-fold Down; FDR = 0.911; PValue = 0.702; mean CPM = 0.7910; interferon, alpha 8" ID="ID_228028138" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKE: 1.03-fold Up; FDR = 0.929; PValue = 0.737; mean CPM = 21.61; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon" ID="ID_1652335609" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB1: 1.02-fold Down; FDR = 0.936; PValue = 0.749; mean CPM = 62.61; transforming growth factor, beta 1" ID="ID_496790186" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FASLG: 1.2-fold Down; FDR = 0.941; PValue = 0.757; mean CPM = 0.8088; Fas ligand (TNF superfamily, member 6)" ID="ID_330853766" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_251945415" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC3: 1.03-fold Down; FDR = 0.952; PValue = 0.78; mean CPM = 13.31; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3" ID="ID_1269002698" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000009289: 1.07-fold Up; FDR = 0.963; PValue = 0.798; mean CPM = 2.536; Uncharacterized protein" ID="ID_983986621" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA14: 1.22-fold Up; FDR = 0.965; PValue = 0.802; mean CPM = 0.8654; interferon, alpha 14" ID="ID_1586597177" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA4: 1.28-fold Down; FDR = 0.983; PValue = 0.829; mean CPM = 0.8584; interferon, alpha 4" ID="ID_372010716" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREBBP: 1.01-fold Down; FDR = 0.993; PValue = 0.847; mean CPM = 137.7; CREB binding protein" ID="ID_975940177" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="E2F2: 1.03-fold Up; FDR = 1; PValue = 0.906; mean CPM = 1.976; E2F transcription factor 2" ID="ID_1081157403" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP9: 1.01-fold Up; FDR = 1; PValue = 0.908; mean CPM = 19.86; caspase 9, apoptosis-related cysteine peptidase" ID="ID_1276024278" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA1: No Change; FDR = 1; PValue = 0.998; mean CPM = 0.8014; interferon, alpha 1" ID="ID_959187271" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Pathways in cancer: Inhibited, FDR = 0.00103, FWER = 0.00952, PValue = 6.56e-05" ID="ID_1520989775" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1991682041" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_1826067536" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL4A1: 7.03-fold Down; FDR = 1.47e-15; PValue = 1.34e-17; mean CPM = 3419; collagen, type IV, alpha 1" ID="ID_1106442321" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFRA: 2.76-fold Up; FDR = 3.93e-14; PValue = 4.67e-16; mean CPM = 492.9; platelet-derived growth factor receptor, alpha polypeptide" ID="ID_875261255" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5A: 2.28-fold Up; FDR = 6.87e-14; PValue = 8.58e-16; mean CPM = 21.55; signal transducer and activator of transcription 5A" ID="ID_426006041" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF1: 5.05-fold Down; FDR = 8.21e-14; PValue = 1.05e-15; mean CPM = 19.54; fibroblast growth factor 1 (acidic)" ID="ID_1841408411" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VEGFC: 2-fold Up; FDR = 1.3e-13; PValue = 1.76e-15; mean CPM = 238.4; Macaca mulatta vascular endothelial growth factor C (VEGFC), mRNA." ID="ID_1932152158" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MET: 2.57-fold Up; FDR = 3.56e-13; PValue = 5.22e-15; mean CPM = 242.4; Macaca mulatta met proto-oncogene (hepatocyte growth factor receptor) (MET), mRNA." ID="ID_536293126" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMC1: 2.28-fold Down; FDR = 6.46e-13; PValue = 1.01e-14; mean CPM = 812.1; laminin, gamma 1 (formerly LAMB2)" ID="ID_1261517800" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB3: 4.82-fold Down; FDR = 1.82e-12; PValue = 3.09e-14; mean CPM = 9.911; transforming growth factor, beta 3" ID="ID_1255477083" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FLT3LG: 4.17-fold Up; FDR = 3.16e-12; PValue = 5.7e-14; mean CPM = 9.659; fms-related tyrosine kinase 3 ligand" ID="ID_854858985" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUP: 6.17-fold Down; FDR = 6.9e-12; PValue = 1.39e-13; mean CPM = 23.29; junction plakoglobin" ID="ID_1092177543" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016591: 4.2-fold Down; FDR = 1.3e-11; PValue = 2.78e-13; mean CPM = 34.90; Uncharacterized protein" ID="ID_896871553" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016587: 4.92-fold Down; FDR = 1.6e-11; PValue = 3.5e-13; mean CPM = 51.70; Uncharacterized protein" ID="ID_999422159" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SUFU: 2.57-fold Down; FDR = 3.35e-11; PValue = 7.94e-13; mean CPM = 40.88; suppressor of fused homolog (Drosophila)" ID="ID_1516124939" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_527934259" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD2: 2.27-fold Down; FDR = 5e-11; PValue = 1.24e-12; mean CPM = 20.66; frizzled homolog 2 (Drosophila)" ID="ID_936209998" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAV: 2.64-fold Down; FDR = 6.04e-11; PValue = 1.51e-12; mean CPM = 337.3; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)" ID="ID_1911728104" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PML: 2.25-fold Up; FDR = 6.36e-11; PValue = 1.6e-12; mean CPM = 94.89; Uncharacterized protein" ID="ID_925528077" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC2: 1.96-fold Up; FDR = 1.01e-10; PValue = 2.62e-12; mean CPM = 53.58; baculoviral IAP repeat-containing 2" ID="ID_1601464669" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA2: 2.84-fold Up; FDR = 7.38e-10; PValue = 2.42e-11; mean CPM = 176.3; integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)" ID="ID_103114715" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_1183915756" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BID: 1.66-fold Up; FDR = 5.41e-09; PValue = 2.19e-10; mean CPM = 35.19; BH3 interacting domain death agonist" ID="ID_166278726" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGFR: 1.84-fold Up; FDR = 6.71e-09; PValue = 2.77e-10; mean CPM = 68.58; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)" ID="ID_1416080999" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DAPK3: 1.57-fold Down; FDR = 8.87e-09; PValue = 3.77e-10; mean CPM = 157.0; death-associated protein kinase 3" ID="ID_1968474466" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF2: 2.42-fold Up; FDR = 9.98e-09; PValue = 4.31e-10; mean CPM = 134.8; fibroblast growth factor 2 (basic)" ID="ID_1026700237" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGFR2: 3.45-fold Down; FDR = 1.04e-08; PValue = 4.53e-10; mean CPM = 5.064; fibroblast growth factor receptor 2" ID="ID_183579688" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1B: 1.64-fold Up; FDR = 1.22e-08; PValue = 5.39e-10; mean CPM = 32.96; Cyclin-dependent kinase inhibitor 1B; Uncharacterized protein" ID="ID_826212702" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1388292484" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RB1: 1.65-fold Up; FDR = 6.01e-08; PValue = 3.2e-09; mean CPM = 59.24; retinoblastoma 1" ID="ID_1723795847" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMO: 2.06-fold Down; FDR = 6.29e-08; PValue = 3.36e-09; mean CPM = 12.79; smoothened homolog (Drosophila)" ID="ID_1830299327" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EPAS1: 1.63-fold Up; FDR = 1.46e-07; PValue = 8.47e-09; mean CPM = 844.8; endothelial PAS domain protein 1" ID="ID_1094938523" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPARD: 1.76-fold Down; FDR = 1.58e-07; PValue = 9.27e-09; mean CPM = 32.10; peroxisome proliferator-activated receptor delta" ID="ID_179371753" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARNT2: 2.2-fold Down; FDR = 1.95e-07; PValue = 1.17e-08; mean CPM = 20.63; aryl-hydrocarbon receptor nuclear translocator 2" ID="ID_1812001110" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RALGDS: 2.6-fold Up; FDR = 2.12e-07; PValue = 1.28e-08; mean CPM = 47.88; ral guanine nucleotide dissociation stimulator" ID="ID_1536360035" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGLN1: 1.62-fold Up; FDR = 2.29e-07; PValue = 1.39e-08; mean CPM = 22.25; egl nine homolog 1 (C. elegans)" ID="ID_1217672726" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFA: 1.92-fold Down; FDR = 2.56e-07; PValue = 1.58e-08; mean CPM = 22.99; platelet-derived growth factor alpha polypeptide" ID="ID_538307306" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_706855509" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1303188120" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RARB: 2.64-fold Up; FDR = 9.11e-07; PValue = 6.49e-08; mean CPM = 8.811; Uncharacterized protein" ID="ID_1711388160" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L1: 1.51-fold Up; FDR = 9.13e-07; PValue = 6.52e-08; mean CPM = 66.15; Bcl-2-like protein 1; Bcl-2-like protein 1 isoform 1; Uncharacterized protein" ID="ID_1784547560" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_537794281" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_124000993" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC3: 2.79-fold Up; FDR = 1.74e-06; PValue = 1.32e-07; mean CPM = 95.34; baculoviral IAP repeat-containing 3" ID="ID_36266413" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_483896324" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGFR3: 3.85-fold Down; FDR = 2.66e-06; PValue = 2.13e-07; mean CPM = 2.800; fibroblast growth factor receptor 3" ID="ID_63372867" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC3: 1.68-fold Down; FDR = 2.72e-06; PValue = 2.19e-07; mean CPM = 13.98; ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)" ID="ID_1843099097" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_1544573838" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL4A5: 2.03-fold Down; FDR = 3.06e-06; PValue = 2.48e-07; mean CPM = 9.810; collagen, type IV, alpha 5" ID="ID_951168834" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STK4: 1.47-fold Up; FDR = 3.87e-06; PValue = 3.24e-07; mean CPM = 35.55; serine/threonine kinase 4" ID="ID_1595394210" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD7: 1.62-fold Down; FDR = 5.66e-06; PValue = 4.95e-07; mean CPM = 34.19; frizzled homolog 7 (Drosophila)" ID="ID_495389442" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1: 5.76-fold Down; FDR = 6.73e-06; PValue = 6.04e-07; mean CPM = 1.536; insulin-like growth factor 1 (somatomedin C)" ID="ID_90607642" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GLI2: 2.04-fold Down; FDR = 8.71e-06; PValue = 8.1e-07; mean CPM = 14.39; GLI family zinc finger 2" ID="ID_604292118" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMC2: 2.28-fold Down; FDR = 9.83e-06; PValue = 9.24e-07; mean CPM = 16.99; laminin, gamma 2" ID="ID_18628955" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1R: 1.51-fold Down; FDR = 1.02e-05; PValue = 9.61e-07; mean CPM = 213.2; insulin-like growth factor 1 receptor" ID="ID_692114162" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_609717500" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF1: 2.6-fold Down; FDR = 1.48e-05; PValue = 1.46e-06; mean CPM = 20.19; TNF receptor-associated factor 1" ID="ID_261520409" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT5A: 1.65-fold Down; FDR = 2.5e-05; PValue = 2.59e-06; mean CPM = 136.4; wingless-type MMTV integration site family, member 5A" ID="ID_1167726596" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APPL1: 1.39-fold Up; FDR = 3.71e-05; PValue = 4.05e-06; mean CPM = 88.56; adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1" ID="ID_623114610" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CUL2: 1.39-fold Up; FDR = 4.17e-05; PValue = 4.61e-06; mean CPM = 55.18; cullin 2" ID="ID_1304956546" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90AA1: 1.41-fold Up; FDR = 4.17e-05; PValue = 4.62e-06; mean CPM = 609.6; heat shock protein 90kDa alpha (cytosolic), class A member 2" ID="ID_412617175" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000009315: 1.44-fold Down; FDR = 4.44e-05; PValue = 4.94e-06; mean CPM = 22.79" ID="ID_1620221930" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_558809779" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RUNX1: 1.45-fold Down; FDR = 0.000122; PValue = 1.56e-05; mean CPM = 39.60; runt-related transcription factor 1" ID="ID_101126834" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TPR: 1.36-fold Up; FDR = 0.000146; PValue = 1.91e-05; mean CPM = 281.7; translocated promoter region (to activated MET oncogene)" ID="ID_328392630" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTGS2: 2.02-fold Up; FDR = 0.000254; PValue = 3.59e-05; mean CPM = 314.5; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)" ID="ID_1772062518" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CKS2: 1.46-fold Up; FDR = 0.000296; PValue = 4.24e-05; mean CPM = 35.30; CDC28 protein kinase regulatory subunit 2" ID="ID_370618863" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VEGFA: 1.47-fold Up; FDR = 0.000317; PValue = 4.59e-05; mean CPM = 463.7; vascular endothelial growth factor A" ID="ID_705300524" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HGF: 1.85-fold Down; FDR = 0.000377; PValue = 5.58e-05; mean CPM = 137.4; hepatocyte growth factor (hepapoietin A; scatter factor)" ID="ID_1449854486" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB2: 1.48-fold Down; FDR = 0.000398; PValue = 5.93e-05; mean CPM = 695.6; laminin, beta 2 (laminin S)" ID="ID_1600761196" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD9: 2.74-fold Down; FDR = 0.000408; PValue = 6.1e-05; mean CPM = 1.789; frizzled homolog 9 (Drosophila)" ID="ID_1180021290" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA3: 1.34-fold Down; FDR = 0.000518; PValue = 7.96e-05; mean CPM = 126.8; integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)" ID="ID_1880951479" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AR: 2.06-fold Up; FDR = 0.000527; PValue = 8.13e-05; mean CPM = 4.804; Macaca mulatta androgen receptor (AR), mRNA." ID="ID_1020919542" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD3: 1.38-fold Up; FDR = 0.000573; PValue = 8.94e-05; mean CPM = 114.9; SMAD family member 3" ID="ID_164320861" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTCH2: 2.16-fold Down; FDR = 0.000581; PValue = 9.08e-05; mean CPM = 4.080; Uncharacterized protein" ID="ID_39410681" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAD: 1.36-fold Down; FDR = 0.000605; PValue = 9.52e-05; mean CPM = 48.46; BCL2-associated agonist of cell death" ID="ID_1972491470" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT1: 7.1-fold Down; FDR = 0.000659; PValue = 0.000105; mean CPM = 2.664; wingless-type MMTV integration site family, member 1" ID="ID_249135231" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGLN3: 1.92-fold Up; FDR = 0.00084; PValue = 0.000138; mean CPM = 11.94; egl nine homolog 3 (C. elegans)" ID="ID_1214004649" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN2B: 1.63-fold Down; FDR = 0.000936; PValue = 0.000156; mean CPM = 17.34; cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)" ID="ID_842987977" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOXO1: 1.49-fold Down; FDR = 0.00109; PValue = 0.000186; mean CPM = 11.95; forkhead box O1" ID="ID_365370213" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTOR: 1.3-fold Down; FDR = 0.00117; PValue = 0.000201; mean CPM = 107.5; mechanistic target of rapamycin (serine/threonine kinase)" ID="ID_1684991130" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DVL3: 1.29-fold Down; FDR = 0.00157; PValue = 0.00028; mean CPM = 67.95; dishevelled, dsh homolog 3 (Drosophila)" ID="ID_560098667" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RET: 2.19-fold Down; FDR = 0.00162; PValue = 0.000292; mean CPM = 6.684; ret proto-oncogene" ID="ID_267096363" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP9: 4.49-fold Down; FDR = 0.00222; PValue = 0.000419; mean CPM = 6.597; matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)" ID="ID_1700308326" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD4: 1.83-fold Up; FDR = 0.00258; PValue = 0.000495; mean CPM = 4.537; frizzled homolog 4 (Drosophila)" ID="ID_1286863675" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHOA: 1.28-fold Down; FDR = 0.00295; PValue = 0.000575; mean CPM = 277.8; ras homolog gene family, member A" ID="ID_1919077548" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSF1R: 1.92-fold Down; FDR = 0.00308; PValue = 0.000604; mean CPM = 3.242; colony stimulating factor 1 receptor" ID="ID_1136528520" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RALA: 1.28-fold Up; FDR = 0.00322; PValue = 0.000638; mean CPM = 42.83; v-ral simian leukemia viral oncogene homolog A (ras related)" ID="ID_599099888" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG1: 1.31-fold Down; FDR = 0.00352; PValue = 0.000707; mean CPM = 53.66; phospholipase C, gamma 1" ID="ID_801232280" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARNT: 1.27-fold Down; FDR = 0.00397; PValue = 0.000814; mean CPM = 57.32; aryl hydrocarbon receptor nuclear translocator" ID="ID_814706307" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CBLC: 2.87-fold Down; FDR = 0.00443; PValue = 0.000923; mean CPM = 3.105; Cas-Br-M (murine) ecotropic retroviral transforming sequence c" ID="ID_1781678609" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1642676959" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90B1: 1.28-fold Down; FDR = 0.00538; PValue = 0.00115; mean CPM = 1017; heat shock protein 90kDa beta (Grp94), member 1" ID="ID_539820081" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MDM2: 1.32-fold Up; FDR = 0.00555; PValue = 0.00119; mean CPM = 148.6; Uncharacterized protein" ID="ID_1371583300" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAX: 1.28-fold Up; FDR = 0.00569; PValue = 0.00123; mean CPM = 29.78; MYC associated factor X" ID="ID_638670270" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_1705335652" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP1: 3.27-fold Down; FDR = 0.00611; PValue = 0.00133; mean CPM = 110.4; matrix metallopeptidase 1 (interstitial collagenase)" ID="ID_507815999" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT7A: 3.46-fold Down; FDR = 0.00638; PValue = 0.0014; mean CPM = 1.036; wingless-type MMTV integration site family, member 7A" ID="ID_501566258" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF12: 1.26-fold Up; FDR = 0.00782; PValue = 0.00177; mean CPM = 34.71; fibroblast growth factor 12" ID="ID_1202113302" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT10A: 4.08-fold Down; FDR = 0.00805; PValue = 0.00183; mean CPM = 0.9138; wingless-type MMTV integration site family, member 10A" ID="ID_453869313" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BMP2: 2.5-fold Up; FDR = 0.00836; PValue = 0.00191; mean CPM = 3.220; bone morphogenetic protein 2" ID="ID_1934152588" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT5B: 1.58-fold Down; FDR = 0.00866; PValue = 0.002; mean CPM = 7.832; wingless-type MMTV integration site family, member 5B" ID="ID_1560965713" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NKX3-1: 2.56-fold Up; FDR = 0.00969; PValue = 0.00226; mean CPM = 1.846; NK3 homeobox 1" ID="ID_228108702" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTBP1: 1.23-fold Down; FDR = 0.0119; PValue = 0.00287; mean CPM = 100.6; C-terminal binding protein 1" ID="ID_1596864176" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFB: 1.97-fold Down; FDR = 0.0133; PValue = 0.00326; mean CPM = 2.424; platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)" ID="ID_1799189486" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT10B: 3.1-fold Down; FDR = 0.0148; PValue = 0.00369; mean CPM = 1.086; wingless-type MMTV integration site family, member 10B" ID="ID_1513281368" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC1: 1.25-fold Up; FDR = 0.0159; PValue = 0.00403; mean CPM = 27.51; histone deacetylase 1" ID="ID_821902812" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FN1: 1.7-fold Down; FDR = 0.0164; PValue = 0.00417; mean CPM = 40317; fibronectin 1" ID="ID_1374098980" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CKS2: 1.94-fold Up; FDR = 0.0164; PValue = 0.00419; mean CPM = 2.062; Cyclin-dependent kinases regulatory subunit 2; Uncharacterized protein" ID="ID_253818977" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTBP2: 1.23-fold Up; FDR = 0.0166; PValue = 0.00423; mean CPM = 49.75; C-terminal binding protein 2" ID="ID_48742341" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA2B: 1.71-fold Down; FDR = 0.0187; PValue = 0.00486; mean CPM = 2.655; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)" ID="ID_422027526" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK2: 1.23-fold Down; FDR = 0.0194; PValue = 0.00507; mean CPM = 36.76; cyclin-dependent kinase 2" ID="ID_580598567" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1222415808" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL8: 2.33-fold Up; FDR = 0.0209; PValue = 0.00552; mean CPM = 2326; interleukin 8" ID="ID_1834425099" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_164417868" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF21: 1.97-fold Up; FDR = 0.0263; PValue = 0.00722; mean CPM = 56.49; fibroblast growth factor 21" ID="ID_436674850" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_1731076384" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC2: 2.96-fold Up; FDR = 0.0309; PValue = 0.00872; mean CPM = 0.9737; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)" ID="ID_1946834663" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD2: 1.2-fold Up; FDR = 0.034; PValue = 0.00976; mean CPM = 57.10; SMAD family member 2" ID="ID_171295935" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF4: 1.21-fold Down; FDR = 0.037; PValue = 0.0108; mean CPM = 29.95; TNF receptor-associated factor 4" ID="ID_1665723067" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFBR1: 1.2-fold Up; FDR = 0.037; PValue = 0.0108; mean CPM = 90.92; transforming growth factor, beta receptor 1" ID="ID_95352265" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TCF7: 1.72-fold Down; FDR = 0.0376; PValue = 0.011; mean CPM = 4.279; transcription factor 7 (T-cell specific, HMG-box)" ID="ID_32302800" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1523548380" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KRAS: 1.35-fold Down; FDR = 0.0401; PValue = 0.0119; mean CPM = 13.10; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog" ID="ID_1855480729" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="E2F1: 1.44-fold Down; FDR = 0.0425; PValue = 0.0127; mean CPM = 8.857; E2F transcription factor 1" ID="ID_1100546258" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZBTB16: 2.9-fold Down; FDR = 0.0439; PValue = 0.0132; mean CPM = 0.9116; zinc finger and BTB domain containing 16" ID="ID_1352044685" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTNNB1: 1.2-fold Up; FDR = 0.0498; PValue = 0.0153; mean CPM = 558.3; catenin (cadherin-associated protein), beta 1, 88kDa" ID="ID_1848697017" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT4: 1.52-fold Down; FDR = 0.0525; PValue = 0.0163; mean CPM = 13.66; wingless-type MMTV integration site family, member 4" ID="ID_1132338243" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NRAS: 1.2-fold Down; FDR = 0.0546; PValue = 0.017; mean CPM = 32.39; neuroblastoma RAS viral (v-ras) oncogene homolog" ID="ID_1856154712" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFBR2: 1.19-fold Up; FDR = 0.0643; PValue = 0.0208; mean CPM = 350.8; transforming growth factor, beta receptor II (70/80kDa)" ID="ID_616345568" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_742282187" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCOA4: 1.18-fold Up; FDR = 0.0699; PValue = 0.0229; mean CPM = 199.5; nuclear receptor coactivator 4" ID="ID_1118642726" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_433849435" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB1: 1.23-fold Up; FDR = 0.0759; PValue = 0.0253; mean CPM = 2700; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)" ID="ID_980337504" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RXRA: 1.18-fold Down; FDR = 0.077; PValue = 0.0257; mean CPM = 35.60; retinoid X receptor, alpha" ID="ID_1544453970" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TCF7L1: 1.2-fold Down; FDR = 0.0783; PValue = 0.0262; mean CPM = 25.11; transcription factor 7-like 1 (T-cell specific, HMG-box)" ID="ID_1595471285" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMA4: 1.2-fold Down; FDR = 0.0793; PValue = 0.0266; mean CPM = 624.4; laminin, alpha 4" ID="ID_1988300597" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF11: 1.44-fold Down; FDR = 0.0841; PValue = 0.0285; mean CPM = 3.869; fibroblast growth factor 11" ID="ID_1064678500" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FADD: 1.18-fold Down; FDR = 0.0936; PValue = 0.0324; mean CPM = 30.89; Uncharacterized protein" ID="ID_137841761" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_714703019" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ETS1: 1.16-fold Up; FDR = 0.0996; PValue = 0.0348; mean CPM = 94.27; v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)" ID="ID_1340797879" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS2: 1.17-fold Up; FDR = 0.1; PValue = 0.0353; mean CPM = 31.79; son of sevenless homolog 2 (Drosophila)" ID="ID_720530459" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC2: 1.15-fold Up; FDR = 0.115; PValue = 0.0414; mean CPM = 93.64; histone deacetylase 2" ID="ID_1339657357" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MECOM: 1.24-fold Up; FDR = 0.115; PValue = 0.0416; mean CPM = 20.27; Uncharacterized protein" ID="ID_109637228" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_57747169" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BMP4: 1.86-fold Down; FDR = 0.119; PValue = 0.0432; mean CPM = 2.163; bone morphogenetic protein 4" ID="ID_1699702713" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND1: 1.17-fold Up; FDR = 0.121; PValue = 0.0443; mean CPM = 867.3; cyclin D1" ID="ID_1840906034" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_811821193" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC5: 1.51-fold Down; FDR = 0.134; PValue = 0.0501; mean CPM = 18.55; Baculoviral IAP repeat-containing protein 5 isoform 1; Uncharacterized protein" ID="ID_1739946814" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_1273109964" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGFR1: 1.15-fold Down; FDR = 0.139; PValue = 0.0525; mean CPM = 89.41; fibroblast growth factor receptor 1" ID="ID_1217995101" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_867096930" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD1: 1.23-fold Down; FDR = 0.154; PValue = 0.0592; mean CPM = 31.65; frizzled homolog 1 (Drosophila)" ID="ID_1853721562" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLD1: 1.24-fold Down; FDR = 0.162; PValue = 0.0634; mean CPM = 15.80; phospholipase D1, phosphatidylcholine-specific" ID="ID_1532241581" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTEN: 1.14-fold Up; FDR = 0.166; PValue = 0.065; mean CPM = 89.60; phosphatase and tensin homolog" ID="ID_560452185" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RUNX1T1: 1.3-fold Down; FDR = 0.174; PValue = 0.0691; mean CPM = 8.800; runt-related transcription factor 1; translocated to, 1 (cyclin D-related)" ID="ID_1030813414" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XIAP: 1.17-fold Up; FDR = 0.177; PValue = 0.0706; mean CPM = 19.21; X-linked inhibitor of apoptosis" ID="ID_1652137185" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF23: 2.01-fold Down; FDR = 0.188; PValue = 0.0759; mean CPM = 0.9718; fibroblast growth factor 23" ID="ID_462255833" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XIAP: 1.26-fold Up; FDR = 0.192; PValue = 0.0778; mean CPM = 5.625; Uncharacterized protein" ID="ID_1093184470" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1563833279" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT3A: 2.28-fold Down; FDR = 0.2; PValue = 0.0823; mean CPM = 0.8811; wingless-type MMTV integration site family, member 3A" ID="ID_1641342143" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KITLG: 1.31-fold Up; FDR = 0.209; PValue = 0.0867; mean CPM = 5.766; KIT ligand" ID="ID_1069445864" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GLI3: 1.21-fold Down; FDR = 0.211; PValue = 0.0875; mean CPM = 42.23; GLI family zinc finger 3" ID="ID_351996268" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000039103: 1.67-fold Down; FDR = 0.221; PValue = 0.0927; mean CPM = 1.310; Uncharacterized protein" ID="ID_1928229212" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STK36: 1.18-fold Down; FDR = 0.223; PValue = 0.0939; mean CPM = 10.64; serine/threonine kinase 36, fused homolog (Drosophila)" ID="ID_1918894471" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BRAF: 1.14-fold Down; FDR = 0.228; PValue = 0.0964; mean CPM = 24.98; v-raf murine sarcoma viral oncogene homolog B1" ID="ID_608768424" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ERBB2: 1.14-fold Down; FDR = 0.23; PValue = 0.0977; mean CPM = 119.0; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)" ID="ID_271480580" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB4: 1.81-fold Down; FDR = 0.237; PValue = 0.101; mean CPM = 1.043; laminin, beta 4" ID="ID_299277651" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF10: 1.55-fold Down; FDR = 0.257; PValue = 0.112; mean CPM = 3.488; fibroblast growth factor 10" ID="ID_1359268856" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNE1: 1.2-fold Up; FDR = 0.278; PValue = 0.123; mean CPM = 6.609; cyclin E1" ID="ID_1263821252" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1A: 1.16-fold Down; FDR = 0.28; PValue = 0.124; mean CPM = 363.2; Cyclin-dependent kinase inhibitor 1; Uncharacterized protein" ID="ID_1319897903" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_545502355" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK6: 1.18-fold Down; FDR = 0.301; PValue = 0.136; mean CPM = 26.51; cyclin-dependent kinase 6" ID="ID_1920899927" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014969: 1.93-fold Down; FDR = 0.303; PValue = 0.137; mean CPM = 0.9384; Uncharacterized protein" ID="ID_143695930" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB3: 1.6-fold Down; FDR = 0.303; PValue = 0.137; mean CPM = 1.445; laminin, beta 3" ID="ID_1809637968" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT3: 1.4-fold Up; FDR = 0.304; PValue = 0.138; mean CPM = 1.843; wingless-type MMTV integration site family, member 3" ID="ID_710516736" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EP300: 1.11-fold Up; FDR = 0.312; PValue = 0.142; mean CPM = 162.8; E1A binding protein p300" ID="ID_213344296" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTCH1: 1.14-fold Down; FDR = 0.32; PValue = 0.147; mean CPM = 13.18; patched homolog 1 (Drosophila)" ID="ID_1924200032" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_1721920790" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD6: 1.11-fold Down; FDR = 0.347; PValue = 0.162; mean CPM = 39.10; frizzled homolog 6 (Drosophila)" ID="ID_340188297" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP53: 1.11-fold Down; FDR = 0.364; PValue = 0.172; mean CPM = 33.25; tumor protein p53" ID="ID_1342260126" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRKL: 1.11-fold Up; FDR = 0.371; PValue = 0.176; mean CPM = 34.10; v-crk sarcoma virus CT10 oncogene homolog (avian)-like" ID="ID_62246749" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1174599804" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2: 1.48-fold Up; FDR = 0.384; PValue = 0.184; mean CPM = 1.344; Uncharacterized protein" ID="ID_384944556" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2: 1.1-fold Up; FDR = 0.394; PValue = 0.191; mean CPM = 102.5; PTK2 protein tyrosine kinase 2" ID="ID_1729161586" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD5: 1.34-fold Down; FDR = 0.405; PValue = 0.197; mean CPM = 2.107; frizzled homolog 5 (Drosophila)" ID="ID_506175830" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RBX1: 1.09-fold Up; FDR = 0.413; PValue = 0.202; mean CPM = 67.97; ring-box 1" ID="ID_1502905681" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL4A3: 1.67-fold Down; FDR = 0.422; PValue = 0.207; mean CPM = 0.9315; collagen, type IV, alpha 3 (Goodpasture antigen)" ID="ID_568534051" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ABL1: 1.09-fold Up; FDR = 0.43; PValue = 0.213; mean CPM = 178.0; c-abl oncogene 1, receptor tyrosine kinase" ID="ID_796686604" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1800658066" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT9A: 1.43-fold Down; FDR = 0.505; PValue = 0.262; mean CPM = 2.172; wingless-type MMTV integration site family, member 9A" ID="ID_1462045285" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VEGFB: 1.1-fold Down; FDR = 0.512; PValue = 0.267; mean CPM = 16.03; vascular endothelial growth factor B" ID="ID_1691317932" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_1411778133" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF18: 1.55-fold Down; FDR = 0.548; PValue = 0.293; mean CPM = 0.9359; fibroblast growth factor 18" ID="ID_1149213257" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDC42: 1.07-fold Down; FDR = 0.608; PValue = 0.335; mean CPM = 91.67; cell division cycle 42" ID="ID_1962905585" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCG: 1.47-fold Down; FDR = 0.609; PValue = 0.336; mean CPM = 0.9297; protein kinase C, gamma" ID="ID_1197277740" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF3: 1.07-fold Up; FDR = 0.611; PValue = 0.338; mean CPM = 34.56; TNF receptor-associated factor 3" ID="ID_375780402" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT2B: 1.29-fold Down; FDR = 0.621; PValue = 0.345; mean CPM = 1.575; wingless-type MMTV integration site family, member 2B" ID="ID_51193493" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL4A6: 1.4-fold Down; FDR = 0.631; PValue = 0.353; mean CPM = 1.078; collagen, type IV, alpha 6" ID="ID_1239898020" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF5: 1.1-fold Down; FDR = 0.646; PValue = 0.364; mean CPM = 54.02; fibroblast growth factor 5" ID="ID_38061552" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90AB1: 1.07-fold Down; FDR = 0.652; PValue = 0.369; mean CPM = 905.8; heat shock protein 90kDa alpha (cytosolic), class B member 1" ID="ID_123651230" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCR: 1.2-fold Down; FDR = 0.687; PValue = 0.397; mean CPM = 1.982; breakpoint cluster region" ID="ID_436664197" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LEF1: 1.2-fold Up; FDR = 0.691; PValue = 0.4; mean CPM = 2.488; lymphoid enhancer-binding factor 1" ID="ID_1750678346" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DVL2: 1.06-fold Up; FDR = 0.708; PValue = 0.414; mean CPM = 30.54; dishevelled, dsh homolog 2 (Drosophila)" ID="ID_636258830" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014966: 1.43-fold Down; FDR = 0.72; PValue = 0.423; mean CPM = 0.9009; Uncharacterized protein" ID="ID_1262456930" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFA: 1.89-fold Up; FDR = 0.725; PValue = 0.428; mean CPM = 0.8701; transforming growth factor, alpha" ID="ID_477741905" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DAPK1: 1.09-fold Up; FDR = 0.727; PValue = 0.429; mean CPM = 42.90; death-associated protein kinase 1" ID="ID_993791003" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCB: 1.86-fold Up; FDR = 0.727; PValue = 0.43; mean CPM = 0.8705; protein kinase C, beta" ID="ID_190049770" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASSF5: 1.2-fold Up; FDR = 0.734; PValue = 0.435; mean CPM = 2.403; Ras association (RalGDS/AF-6) domain family member 5" ID="ID_1158938740" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF9: 1.77-fold Up; FDR = 0.74; PValue = 0.441; mean CPM = 0.8485; fibroblast growth factor 9 (glia-activating factor)" ID="ID_704677799" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90AA1: 1.8-fold Up; FDR = 0.749; PValue = 0.449; mean CPM = 0.8328; heat shock protein 90kDa alpha (cytosolic), class A member 1" ID="ID_1739283614" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="E2F3: 1.08-fold Up; FDR = 0.751; PValue = 0.452; mean CPM = 11.79; E2F transcription factor 3" ID="ID_948739285" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HHIP: 1.36-fold Down; FDR = 0.764; PValue = 0.462; mean CPM = 0.9041; hedgehog interacting protein" ID="ID_1586774762" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_110411576" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC2A1: 1.06-fold Down; FDR = 0.782; PValue = 0.479; mean CPM = 105.3; solute carrier family 2 (facilitated glucose transporter), member 1" ID="ID_34990799" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF8: 1.75-fold Down; FDR = 0.783; PValue = 0.48; mean CPM = 0.8245; Uncharacterized protein" ID="ID_1238701465" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRK: 1.05-fold Up; FDR = 0.791; PValue = 0.488; mean CPM = 59.92; v-crk sarcoma virus CT10 oncogene homolog (avian)" ID="ID_1400621534" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIAS2: 1.06-fold Down; FDR = 0.807; PValue = 0.503; mean CPM = 19.53; protein inhibitor of activated STAT, 2" ID="ID_940974933" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VHL: 1.07-fold Up; FDR = 0.807; PValue = 0.504; mean CPM = 12.46; Uncharacterized protein" ID="ID_1618361197" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF14: 1.13-fold Down; FDR = 0.809; PValue = 0.505; mean CPM = 6.007; fibroblast growth factor 14" ID="ID_442474574" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAX: 1.05-fold Up; FDR = 0.809; PValue = 0.506; mean CPM = 162.4; Uncharacterized protein" ID="ID_453108254" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CBL: 1.05-fold Down; FDR = 0.824; PValue = 0.524; mean CPM = 51.06; Cas-Br-M (murine) ecotropic retroviral transforming sequence" ID="ID_1232123094" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYCS: 1.05-fold Up; FDR = 0.854; PValue = 0.565; mean CPM = 93.43; cytochrome c, somatic" ID="ID_1102739624" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT16: 1.27-fold Down; FDR = 0.857; PValue = 0.571; mean CPM = 0.9003; wingless-type MMTV integration site family, member 16" ID="ID_338931243" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1387099204" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CBLB: 1.04-fold Down; FDR = 0.859; PValue = 0.574; mean CPM = 64.59; Cas-Br-M (murine) ecotropic retroviral transforming sequence b" ID="ID_1012654311" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000040219: 1.08-fold Up; FDR = 0.86; PValue = 0.575; mean CPM = 8.818; Uncharacterized protein" ID="ID_745064848" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TCEB2: 1.04-fold Down; FDR = 0.865; PValue = 0.581; mean CPM = 46.05; transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)" ID="ID_603398721" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1031285832" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC7: 1.52-fold Down; FDR = 0.881; PValue = 0.601; mean CPM = 0.8439; baculoviral IAP repeat containing 7" ID="ID_965082742" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF13: 1.24-fold Up; FDR = 0.882; PValue = 0.602; mean CPM = 1.024; Fibroblast growth factor 13 isoform 1; Uncharacterized protein" ID="ID_1568290903" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGLN2: 1.04-fold Up; FDR = 0.884; PValue = 0.604; mean CPM = 107.5; egl nine homolog 2 (C. elegans)" ID="ID_359210401" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK4: 1.04-fold Up; FDR = 0.899; PValue = 0.626; mean CPM = 65.45; cyclin-dependent kinase 4" ID="ID_1324248296" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TCEB2: 1.06-fold Up; FDR = 0.901; PValue = 0.637; mean CPM = 6.295; transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)" ID="ID_257811636" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF3: 1.22-fold Down; FDR = 0.903; PValue = 0.641; mean CPM = 0.7938; fibroblast growth factor 3 (murine mammary tumor virus integration site (v-int-2) oncogene homolog)" ID="ID_529908074" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT11: 1.18-fold Up; FDR = 0.903; PValue = 0.641; mean CPM = 1.340; wingless-type MMTV integration site family, member 11" ID="ID_88375746" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB2: 1.05-fold Down; FDR = 0.903; PValue = 0.655; mean CPM = 110.8; transforming growth factor, beta 2" ID="ID_1239930887" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF17: 1.34-fold Down; FDR = 0.903; PValue = 0.662; mean CPM = 0.8230; fibroblast growth factor 17" ID="ID_1231256236" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSF2RA: 1.19-fold Up; FDR = 0.906; PValue = 0.666; mean CPM = 0.9897; colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)" ID="ID_882075316" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD4: 1.03-fold Down; FDR = 0.906; PValue = 0.666; mean CPM = 43.02; SMAD family member 4" ID="ID_1353322153" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RXRG: 1.32-fold Up; FDR = 0.915; PValue = 0.714; mean CPM = 0.8688; retinoid X receptor, gamma" ID="ID_1120986344" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOS2: 1.4-fold Down; FDR = 0.917; PValue = 0.718; mean CPM = 0.8546; nitric oxide synthase 2, inducible" ID="ID_1406937489" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSF3R: 1.13-fold Down; FDR = 0.921; PValue = 0.723; mean CPM = 0.9331; colony stimulating factor 3 receptor (granulocyte)" ID="ID_1231133254" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF19: 1.33-fold Down; FDR = 0.921; PValue = 0.724; mean CPM = 0.8101; fibroblast growth factor 19" ID="ID_1369287474" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNA1: 1.28-fold Down; FDR = 0.928; PValue = 0.736; mean CPM = 0.8658; cyclin A1" ID="ID_1501915754" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTBP2: 1.24-fold Up; FDR = 0.934; PValue = 0.746; mean CPM = 0.8168; C-terminal binding protein 2" ID="ID_833866030" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPI1: 1.12-fold Down; FDR = 0.935; PValue = 0.747; mean CPM = 1.030; spleen focus forming virus (SFFV) proviral integration oncogene spi1" ID="ID_1944195610" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB1: 1.02-fold Down; FDR = 0.936; PValue = 0.749; mean CPM = 62.61; transforming growth factor, beta 1" ID="ID_336881649" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FASLG: 1.2-fold Down; FDR = 0.941; PValue = 0.757; mean CPM = 0.8088; Fas ligand (TNF superfamily, member 6)" ID="ID_1796714021" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_1333376921" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FLT3: 1.48-fold Down; FDR = 0.948; PValue = 0.77; mean CPM = 0.8603; fms-related tyrosine kinase 3" ID="ID_1469986505" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF6: 1.15-fold Up; FDR = 0.948; PValue = 0.773; mean CPM = 0.8082; fibroblast growth factor 6" ID="ID_1319647226" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GLI1: 1.1-fold Down; FDR = 0.956; PValue = 0.787; mean CPM = 1.155; GLI family zinc finger 1" ID="ID_138964741" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNE2: 1.05-fold Up; FDR = 0.962; PValue = 0.796; mean CPM = 6.415; cyclin E2" ID="ID_599056948" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TFG: 1.02-fold Up; FDR = 0.962; PValue = 0.796; mean CPM = 90.49; TRK-fused gene" ID="ID_766404988" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000009289: 1.07-fold Up; FDR = 0.963; PValue = 0.798; mean CPM = 2.536; Uncharacterized protein" ID="ID_747910133" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_121064618" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DAPK2: 1.07-fold Down; FDR = 0.976; PValue = 0.818; mean CPM = 1.495; death-associated protein kinase 2" ID="ID_10966580" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NTRK1: 1.07-fold Up; FDR = 0.977; PValue = 0.82; mean CPM = 1.195; neurotrophic tyrosine kinase, receptor, type 1" ID="ID_563005295" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG2: 1.06-fold Up; FDR = 0.985; PValue = 0.834; mean CPM = 2.248; phospholipase C, gamma 2 (phosphatidylinositol-specific)" ID="ID_1742369540" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT8B: 1.21-fold Down; FDR = 0.987; PValue = 0.838; mean CPM = 0.8506; wingless-type MMTV integration site family, member 8B" ID="ID_282917894" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREBBP: 1.01-fold Down; FDR = 0.993; PValue = 0.847; mean CPM = 137.7; CREB binding protein" ID="ID_1880473504" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASSF1: 1.01-fold Down; FDR = 1; PValue = 0.87; mean CPM = 87.09; Uncharacterized protein" ID="ID_764524397" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAX8: 1.06-fold Down; FDR = 1; PValue = 0.878; mean CPM = 0.8841; paired box 8" ID="ID_323370577" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFRB: 1.01-fold Up; FDR = 1; PValue = 0.883; mean CPM = 391.1; platelet-derived growth factor receptor, beta polypeptide" ID="ID_128412551" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGF: 1.06-fold Down; FDR = 1; PValue = 0.885; mean CPM = 0.8917; epidermal growth factor" ID="ID_115962025" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT2: 1.07-fold Down; FDR = 1; PValue = 0.888; mean CPM = 0.8103; wingless-type MMTV integration site family member 2" ID="ID_383416189" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DCC: 1.02-fold Up; FDR = 1; PValue = 0.89; mean CPM = 0.8383; deleted in colorectal carcinoma" ID="ID_259820125" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD3: 1.03-fold Up; FDR = 1; PValue = 0.903; mean CPM = 1.636; frizzled homolog 3 (Drosophila)" ID="ID_1353583596" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="E2F2: 1.03-fold Up; FDR = 1; PValue = 0.906; mean CPM = 1.976; E2F transcription factor 2" ID="ID_1332912487" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP9: 1.01-fold Up; FDR = 1; PValue = 0.908; mean CPM = 19.86; caspase 9, apoptosis-related cysteine peptidase" ID="ID_1812926823" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD10: 1.04-fold Down; FDR = 1; PValue = 0.919; mean CPM = 0.8435; frizzled homolog 10 (Drosophila)" ID="ID_1424406791" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPARG: 1.01-fold Down; FDR = 1; PValue = 0.929; mean CPM = 5.609; peroxisome proliferator-activated receptor gamma" ID="ID_1079349326" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RALBP1: 1.01-fold Up; FDR = 1; PValue = 0.943; mean CPM = 72.93; Uncharacterized protein" ID="ID_165125562" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT6: 1.13-fold Down; FDR = 1; PValue = 0.956; mean CPM = 0.8230; wingless-type MMTV integration site family, member 6" ID="ID_633293560" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP2: No Change; FDR = 1; PValue = 0.976; mean CPM = 210.3; matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)" ID="ID_1951057610" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT9B: 1.03-fold Up; FDR = 1; PValue = 0.991; mean CPM = 0.8041; wingless-type MMTV integration site family, member 9B" ID="ID_1373945042" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FIGF: 1.07-fold Up; FDR = 1; PValue = 0.995; mean CPM = 0.8037; c-fos induced growth factor (vascular endothelial growth factor D)" ID="ID_362313832" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF20: No Change; FDR = 1; PValue = 1; mean CPM = 0.7796; fibroblast growth factor 20" ID="ID_1631768648" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KLK3: No Change; FDR = 1; PValue = 1; mean CPM = 0.7851; kallikrein-related peptidase 3" ID="ID_752409709" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg PI3K-Akt signaling pathway: Inhibited, FDR = 0.00103, FWER = 0.0103, PValue = 7.1e-05" ID="ID_1045940751" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TLR2: 8.94-fold Up; FDR = 6.97e-23; PValue = 1.25e-25; mean CPM = 18.41; toll-like receptor 2" ID="ID_1101563881" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSF1: 7.34-fold Up; FDR = 4.6e-20; PValue = 1.69e-22; mean CPM = 149.8; colony stimulating factor 1 (macrophage)" ID="ID_1806235510" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_1201142158" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL4A1: 7.03-fold Down; FDR = 1.47e-15; PValue = 1.34e-17; mean CPM = 3419; collagen, type IV, alpha 1" ID="ID_15231538" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL5A1: 4.69-fold Down; FDR = 3.09e-15; PValue = 2.99e-17; mean CPM = 1718; collagen, type V, alpha 1" ID="ID_1670870549" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL3A1: 20.5-fold Down; FDR = 5.71e-15; PValue = 5.82e-17; mean CPM = 5961; collagen, type III, alpha 1" ID="ID_791648860" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL11A1: 12.2-fold Down; FDR = 8.67e-15; PValue = 9.24e-17; mean CPM = 318.0; collagen, type XI, alpha 1" ID="ID_1028375737" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA5: 3.79-fold Down; FDR = 1.33e-14; PValue = 1.48e-16; mean CPM = 1237; integrin, alpha 5 (fibronectin receptor, alpha polypeptide)" ID="ID_943510438" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFRA: 2.76-fold Up; FDR = 3.93e-14; PValue = 4.67e-16; mean CPM = 492.9; platelet-derived growth factor receptor, alpha polypeptide" ID="ID_1897132125" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL6A3: 4.93-fold Down; FDR = 5.63e-14; PValue = 6.87e-16; mean CPM = 1415; collagen, type VI, alpha 3" ID="ID_1215802542" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF1: 5.05-fold Down; FDR = 8.21e-14; PValue = 1.05e-15; mean CPM = 19.54; fibroblast growth factor 1 (acidic)" ID="ID_78712259" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL1A1: 21.5-fold Down; FDR = 1.13e-13; PValue = 1.5e-15; mean CPM = 15389; collagen, type I, alpha 1" ID="ID_187020816" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG10: 2.27-fold Up; FDR = 1.24e-13; PValue = 1.66e-15; mean CPM = 24.29; guanine nucleotide binding protein (G protein), gamma 10" ID="ID_1421868102" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VEGFC: 2-fold Up; FDR = 1.3e-13; PValue = 1.76e-15; mean CPM = 238.4; Macaca mulatta vascular endothelial growth factor C (VEGFC), mRNA." ID="ID_1088418148" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL7: 9.03-fold Up; FDR = 1.39e-13; PValue = 1.9e-15; mean CPM = 5.288; interleukin 7" ID="ID_1029923796" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MET: 2.57-fold Up; FDR = 3.56e-13; PValue = 5.22e-15; mean CPM = 242.4; Macaca mulatta met proto-oncogene (hepatocyte growth factor receptor) (MET), mRNA." ID="ID_1809663770" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL1A2: 10.7-fold Down; FDR = 3.82e-13; PValue = 5.68e-15; mean CPM = 17923; collagen, type I, alpha 2" ID="ID_278388982" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMC1: 2.28-fold Down; FDR = 6.46e-13; PValue = 1.01e-14; mean CPM = 812.1; laminin, gamma 1 (formerly LAMB2)" ID="ID_1773702721" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EPHA2: 2.06-fold Down; FDR = 4.54e-12; PValue = 8.63e-14; mean CPM = 77.86; EPH receptor A2" ID="ID_113075343" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3L2: 2.11-fold Down; FDR = 5.05e-12; PValue = 9.78e-14; mean CPM = 64.33; cAMP responsive element binding protein 3-like 2" ID="ID_1592366923" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016591: 4.2-fold Down; FDR = 1.3e-11; PValue = 2.78e-13; mean CPM = 34.90; Uncharacterized protein" ID="ID_1511208025" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016587: 4.92-fold Down; FDR = 1.6e-11; PValue = 3.5e-13; mean CPM = 51.70; Uncharacterized protein" ID="ID_513145909" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAV: 2.64-fold Down; FDR = 6.04e-11; PValue = 1.51e-12; mean CPM = 337.3; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)" ID="ID_1287927987" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PKN2: 1.67-fold Up; FDR = 6.49e-11; PValue = 1.64e-12; mean CPM = 64.77; protein kinase N2" ID="ID_1288026721" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND3: 2.27-fold Down; FDR = 8.38e-11; PValue = 2.15e-12; mean CPM = 86.90; cyclin D3" ID="ID_1348309928" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL5A3: 5.21-fold Down; FDR = 1.78e-10; PValue = 4.98e-12; mean CPM = 79.70; collagen, type V, alpha 3" ID="ID_1593607944" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THBS2: 6.46-fold Down; FDR = 3.61e-10; PValue = 1.1e-11; mean CPM = 199.9; thrombospondin 2" ID="ID_547206555" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB8: 3.97-fold Up; FDR = 6.37e-10; PValue = 2.06e-11; mean CPM = 11.37; integrin, beta 8" ID="ID_652787180" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA2: 2.84-fold Up; FDR = 7.38e-10; PValue = 2.42e-11; mean CPM = 176.3; integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)" ID="ID_542022069" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3L1: 1.99-fold Down; FDR = 1.52e-09; PValue = 5.36e-11; mean CPM = 211.4; cAMP responsive element binding protein 3-like 1" ID="ID_875532483" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB3: 5.02-fold Down; FDR = 1.72e-09; PValue = 6.17e-11; mean CPM = 43.21; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)" ID="ID_571317533" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL5A2: 2.25-fold Down; FDR = 2.26e-09; PValue = 8.27e-11; mean CPM = 2999; collagen, type V, alpha 2" ID="ID_268624069" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNB4: 2.14-fold Up; FDR = 2.52e-09; PValue = 9.35e-11; mean CPM = 33.45; guanine nucleotide binding protein (G protein), beta polypeptide 4" ID="ID_930432948" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR4: 3.45-fold Up; FDR = 3.1e-09; PValue = 1.19e-10; mean CPM = 7.456; Macaca mulatta toll-like receptor 4 (TLR4), mRNA." ID="ID_1372003401" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_998774666" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGFR: 1.84-fold Up; FDR = 6.71e-09; PValue = 2.77e-10; mean CPM = 68.58; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)" ID="ID_1761654206" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRS1: 2.78-fold Up; FDR = 7.67e-09; PValue = 3.19e-10; mean CPM = 26.55; Uncharacterized protein" ID="ID_860451630" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB5: 1.61-fold Down; FDR = 8.23e-09; PValue = 3.47e-10; mean CPM = 471.0; integrin, beta 5" ID="ID_1582718888" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF2: 2.42-fold Up; FDR = 9.98e-09; PValue = 4.31e-10; mean CPM = 134.8; fibroblast growth factor 2 (basic)" ID="ID_1080171409" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGFR2: 3.45-fold Down; FDR = 1.04e-08; PValue = 4.53e-10; mean CPM = 5.064; fibroblast growth factor receptor 2" ID="ID_1369338134" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1B: 1.64-fold Up; FDR = 1.22e-08; PValue = 5.39e-10; mean CPM = 32.96; Cyclin-dependent kinase inhibitor 1B; Uncharacterized protein" ID="ID_1021529062" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INSR: 1.93-fold Down; FDR = 1.24e-08; PValue = 5.48e-10; mean CPM = 118.3; insulin receptor" ID="ID_14773499" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA10: 4.95-fold Down; FDR = 1.77e-08; PValue = 8.13e-10; mean CPM = 5.184; integrin, alpha 10" ID="ID_828491278" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1760632038" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA8: 4.04-fold Down; FDR = 5.89e-08; PValue = 3.12e-09; mean CPM = 145.8; integrin, alpha 8" ID="ID_979817530" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THBS3: 1.97-fold Up; FDR = 7.19e-08; PValue = 3.88e-09; mean CPM = 128.6; thrombospondin 3" ID="ID_1610526194" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COMP: 4.64-fold Down; FDR = 7.47e-08; PValue = 4.04e-09; mean CPM = 13.27; cartilage oligomeric matrix protein" ID="ID_622360440" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EFNA4: 3.75-fold Down; FDR = 2.37e-07; PValue = 1.45e-08; mean CPM = 2.749; ephrin-A4" ID="ID_1772580154" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFA: 1.92-fold Down; FDR = 2.56e-07; PValue = 1.58e-08; mean CPM = 22.99; platelet-derived growth factor alpha polypeptide" ID="ID_194621127" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG11: 1.65-fold Up; FDR = 2.71e-07; PValue = 1.68e-08; mean CPM = 86.60; guanine nucleotide binding protein (G protein), gamma 11" ID="ID_1201257887" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNC: 1.97-fold Down; FDR = 4.07e-07; PValue = 2.63e-08; mean CPM = 2667; tenascin C" ID="ID_1849275636" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1425884399" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L1: 1.51-fold Up; FDR = 9.13e-07; PValue = 6.52e-08; mean CPM = 66.15; Bcl-2-like protein 1; Bcl-2-like protein 1 isoform 1; Uncharacterized protein" ID="ID_1919754119" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_663168612" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_856606926" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THBS1: 2.74-fold Down; FDR = 1.68e-06; PValue = 1.28e-07; mean CPM = 25785; thrombospondin 1" ID="ID_1230239155" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR2: 1.74-fold Up; FDR = 1.85e-06; PValue = 1.44e-07; mean CPM = 26.05; interferon (alpha, beta and omega) receptor 2" ID="ID_1345462673" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGFR3: 3.85-fold Down; FDR = 2.66e-06; PValue = 2.13e-07; mean CPM = 2.800; fibroblast growth factor receptor 3" ID="ID_1123623101" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL4A5: 2.03-fold Down; FDR = 3.06e-06; PValue = 2.48e-07; mean CPM = 9.810; collagen, type IV, alpha 5" ID="ID_131649726" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKAA2: 1.7-fold Down; FDR = 5.6e-06; PValue = 4.89e-07; mean CPM = 11.23; protein kinase, AMP-activated, alpha 2 catalytic subunit" ID="ID_992428286" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL6A1: 1.85-fold Down; FDR = 6.65e-06; PValue = 5.96e-07; mean CPM = 1937; collagen, type VI, alpha 1" ID="ID_806565679" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1: 5.76-fold Down; FDR = 6.73e-06; PValue = 6.04e-07; mean CPM = 1.536; insulin-like growth factor 1 (somatomedin C)" ID="ID_1918178802" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMC2: 2.28-fold Down; FDR = 9.83e-06; PValue = 9.24e-07; mean CPM = 16.99; laminin, gamma 2" ID="ID_537653131" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TSC2: 1.44-fold Down; FDR = 1e-05; PValue = 9.42e-07; mean CPM = 124.0; tuberous sclerosis 2" ID="ID_234263149" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1R: 1.51-fold Down; FDR = 1.02e-05; PValue = 9.61e-07; mean CPM = 213.2; insulin-like growth factor 1 receptor" ID="ID_810137458" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_780995003" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="OSMR: 1.49-fold Up; FDR = 1.63e-05; PValue = 1.62e-06; mean CPM = 180.8; Uncharacterized protein" ID="ID_702526045" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPTOR: 1.4-fold Down; FDR = 2.58e-05; PValue = 2.69e-06; mean CPM = 53.57; regulatory associated protein of MTOR, complex 1" ID="ID_1493901324" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DDIT4: 1.72-fold Up; FDR = 4.15e-05; PValue = 4.58e-06; mean CPM = 395.1; DNA-damage-inducible transcript 4" ID="ID_1436192750" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90AA1: 1.41-fold Up; FDR = 4.17e-05; PValue = 4.62e-06; mean CPM = 609.6; heat shock protein 90kDa alpha (cytosolic), class A member 2" ID="ID_483941591" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R1B: 1.39-fold Down; FDR = 4.37e-05; PValue = 4.86e-06; mean CPM = 233.1; protein phosphatase 2, regulatory subunit A, beta" ID="ID_1276015119" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB2: 1.38-fold Down; FDR = 4.66e-05; PValue = 5.24e-06; mean CPM = 61.90; ribosomal protein S6 kinase, 70kDa, polypeptide 2" ID="ID_1093882887" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL6R: 3.84-fold Down; FDR = 6.68e-05; PValue = 7.89e-06; mean CPM = 4.840; interleukin 6 receptor" ID="ID_57079886" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R3C: 1.5-fold Up; FDR = 7.46e-05; PValue = 8.92e-06; mean CPM = 15.53; protein phosphatase 2 (formerly 2A), regulatory subunit B'', gamma" ID="ID_1026080687" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPP1: 2.25-fold Down; FDR = 7.74e-05; PValue = 9.29e-06; mean CPM = 35.33; secreted phosphoprotein 1" ID="ID_715565122" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PCK2: 1.8-fold Up; FDR = 8.33e-05; PValue = 1.01e-05; mean CPM = 110.4; phosphoenolpyruvate carboxykinase 2 (mitochondrial)" ID="ID_1083653397" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R5A: 1.45-fold Up; FDR = 0.000141; PValue = 1.83e-05; mean CPM = 21.64; protein phosphatase 2, regulatory subunit B', alpha" ID="ID_1560844256" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNB3: 1.91-fold Down; FDR = 0.000162; PValue = 2.14e-05; mean CPM = 7.202; guanine nucleotide binding protein (G protein), beta polypeptide 3" ID="ID_1511673483" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2CB: 1.35-fold Up; FDR = 0.000215; PValue = 2.96e-05; mean CPM = 59.68; protein phosphatase 2, catalytic subunit, beta isozyme" ID="ID_1669352124" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="G6PC3: 1.37-fold Down; FDR = 0.000225; PValue = 3.11e-05; mean CPM = 33.42; glucose 6 phosphatase, catalytic, 3" ID="ID_392178430" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB5: 2.1-fold Down; FDR = 0.000248; PValue = 3.48e-05; mean CPM = 4.269; cAMP responsive element binding protein 5" ID="ID_1760999121" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL6A2: 1.47-fold Down; FDR = 0.000287; PValue = 4.1e-05; mean CPM = 1544; collagen, type VI, alpha 2" ID="ID_1890629743" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VEGFA: 1.47-fold Up; FDR = 0.000317; PValue = 4.59e-05; mean CPM = 463.7; vascular endothelial growth factor A" ID="ID_437404754" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HGF: 1.85-fold Down; FDR = 0.000377; PValue = 5.58e-05; mean CPM = 137.4; hepatocyte growth factor (hepapoietin A; scatter factor)" ID="ID_1965712964" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB2: 1.48-fold Down; FDR = 0.000398; PValue = 5.93e-05; mean CPM = 695.6; laminin, beta 2 (laminin S)" ID="ID_104029385" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF2: 1.34-fold Up; FDR = 0.000403; PValue = 6.01e-05; mean CPM = 39.83; activating transcription factor 2" ID="ID_939299447" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA3: 1.34-fold Down; FDR = 0.000518; PValue = 7.96e-05; mean CPM = 126.8; integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)" ID="ID_612893226" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R2B: 7.66-fold Down; FDR = 0.000564; PValue = 8.78e-05; mean CPM = 4.510; protein phosphatase 2, regulatory subunit B, beta" ID="ID_1581055267" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAD: 1.36-fold Down; FDR = 0.000605; PValue = 9.52e-05; mean CPM = 48.46; BCL2-associated agonist of cell death" ID="ID_127253765" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKAA1: 1.32-fold Up; FDR = 0.000825; PValue = 0.000135; mean CPM = 40.69; protein kinase, AMP-activated, alpha 1 catalytic subunit" ID="ID_1660517277" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ANGPT4: 4.02-fold Down; FDR = 0.000955; PValue = 0.00016; mean CPM = 1.231; angiopoietin 4" ID="ID_795568848" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NR4A1: 1.74-fold Down; FDR = 0.00108; PValue = 0.000184; mean CPM = 312.6; nuclear receptor subfamily 4, group A, member 1" ID="ID_409436365" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTOR: 1.3-fold Down; FDR = 0.00117; PValue = 0.000201; mean CPM = 107.5; mechanistic target of rapamycin (serine/threonine kinase)" ID="ID_162615189" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK3: 2.31-fold Up; FDR = 0.00186; PValue = 0.000342; mean CPM = 2.154; Janus kinase 3" ID="ID_997624799" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NGF: 1.32-fold Up; FDR = 0.00212; PValue = 0.000396; mean CPM = 198.5; nerve growth factor (beta polypeptide)" ID="ID_258466431" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF4E2: 1.3-fold Down; FDR = 0.00249; PValue = 0.000475; mean CPM = 29.85; eukaryotic translation initiation factor 4E family member 2" ID="ID_1847601933" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="OSM: 4.6-fold Down; FDR = 0.00251; PValue = 0.00048; mean CPM = 0.9104; oncostatin M" ID="ID_1422921831" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF4: 1.29-fold Up; FDR = 0.00296; PValue = 0.000579; mean CPM = 618.7; activating transcription factor 4 (tax-responsive enhancer element B67)" ID="ID_488700610" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PKN3: 1.86-fold Down; FDR = 0.00308; PValue = 0.000604; mean CPM = 5.065; protein kinase N3" ID="ID_795807116" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSF1R: 1.92-fold Down; FDR = 0.00308; PValue = 0.000604; mean CPM = 3.242; colony stimulating factor 1 receptor" ID="ID_1495857882" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EFNA2: 4.72-fold Down; FDR = 0.00348; PValue = 0.000699; mean CPM = 1.248; ephrin-A2" ID="ID_1392188718" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB4: 1.66-fold Down; FDR = 0.00369; PValue = 0.000748; mean CPM = 5.291; integrin, beta 4" ID="ID_1601258092" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG12: 1.31-fold Up; FDR = 0.00387; PValue = 0.000792; mean CPM = 24.97; guanine nucleotide binding protein (G protein), gamma 12" ID="ID_1092316970" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SGK1: 1.36-fold Down; FDR = 0.0048; PValue = 0.00101; mean CPM = 395.0; Uncharacterized protein" ID="ID_21385622" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R5D: 1.27-fold Down; FDR = 0.00482; PValue = 0.00101; mean CPM = 35.61; protein phosphatase 2, regulatory subunit B', delta" ID="ID_1938300317" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90B1: 1.28-fold Down; FDR = 0.00538; PValue = 0.00115; mean CPM = 1017; heat shock protein 90kDa beta (Grp94), member 1" ID="ID_1816386839" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MDM2: 1.32-fold Up; FDR = 0.00555; PValue = 0.00119; mean CPM = 148.6; Uncharacterized protein" ID="ID_1296535086" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF12: 1.26-fold Up; FDR = 0.00782; PValue = 0.00177; mean CPM = 34.71; fibroblast growth factor 12" ID="ID_1573730430" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR1: 1.27-fold Up; FDR = 0.0101; PValue = 0.00237; mean CPM = 82.39; Uncharacterized protein" ID="ID_516840781" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EFNA3: 2.71-fold Down; FDR = 0.0114; PValue = 0.00271; mean CPM = 1.699; ephrin-A3" ID="ID_1673839082" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EFNA1: 2.73-fold Down; FDR = 0.0114; PValue = 0.00272; mean CPM = 1.130; ephrin-A1" ID="ID_769469762" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFB: 1.97-fold Down; FDR = 0.0133; PValue = 0.00326; mean CPM = 2.424; platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)" ID="ID_1624927584" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EPOR: 1.56-fold Down; FDR = 0.014; PValue = 0.00347; mean CPM = 3.898; erythropoietin receptor" ID="ID_571940746" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDC37: 1.23-fold Down; FDR = 0.0152; PValue = 0.00381; mean CPM = 275.9; cell division cycle 37 homolog (S. cerevisiae)" ID="ID_1732414979" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCZ: 1.51-fold Up; FDR = 0.0152; PValue = 0.00381; mean CPM = 10.46; protein kinase C, zeta" ID="ID_711822530" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FN1: 1.7-fold Down; FDR = 0.0164; PValue = 0.00417; mean CPM = 40317; fibronectin 1" ID="ID_810043497" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA2B: 1.71-fold Down; FDR = 0.0187; PValue = 0.00486; mean CPM = 2.655; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)" ID="ID_1449338296" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK2: 1.23-fold Down; FDR = 0.0194; PValue = 0.00507; mean CPM = 36.76; cyclin-dependent kinase 2" ID="ID_1740897174" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_104181814" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1281617180" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF21: 1.97-fold Up; FDR = 0.0263; PValue = 0.00722; mean CPM = 56.49; fibroblast growth factor 21" ID="ID_1621226081" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB1: 1.21-fold Up; FDR = 0.0313; PValue = 0.00884; mean CPM = 36.07; cAMP responsive element binding protein 1" ID="ID_486697263" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KDR: 2.01-fold Up; FDR = 0.0328; PValue = 0.00936; mean CPM = 2.053; kinase insert domain receptor (a type III receptor tyrosine kinase)" ID="ID_723992940" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MCL1: 1.2-fold Up; FDR = 0.0335; PValue = 0.00961; mean CPM = 193.8; myeloid cell leukemia sequence 1 (BCL2-related)" ID="ID_1186420831" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDPK1: 1.24-fold Down; FDR = 0.0361; PValue = 0.0105; mean CPM = 17.53; 3-phosphoinositide dependent protein kinase-1" ID="ID_586543836" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL2A1: 2.38-fold Down; FDR = 0.0368; PValue = 0.0107; mean CPM = 1.117; Uncharacterized protein" ID="ID_1368806163" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1883130674" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KRAS: 1.35-fold Down; FDR = 0.0401; PValue = 0.0119; mean CPM = 13.10; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog" ID="ID_700775856" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NRAS: 1.2-fold Down; FDR = 0.0546; PValue = 0.017; mean CPM = 32.39; neuroblastoma RAS viral (v-ras) oncogene homolog" ID="ID_1021925786" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TSC1: 1.19-fold Down; FDR = 0.0564; PValue = 0.0177; mean CPM = 38.34; tuberous sclerosis 1" ID="ID_1573830852" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="YWHAH: 1.18-fold Down; FDR = 0.057; PValue = 0.018; mean CPM = 69.27; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide" ID="ID_594912685" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L11: 1.34-fold Up; FDR = 0.0609; PValue = 0.0195; mean CPM = 18.38; BCL2-like 11 (apoptosis facilitator)" ID="ID_1047184757" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PHLPP2: 1.19-fold Down; FDR = 0.0673; PValue = 0.0219; mean CPM = 33.67; PH domain and leucine rich repeat protein phosphatase 2" ID="ID_380244752" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_33212580" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL7R: 1.76-fold Down; FDR = 0.0698; PValue = 0.0229; mean CPM = 3.067; interleukin 7 receptor" ID="ID_1555009113" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSF3: 2.55-fold Up; FDR = 0.0701; PValue = 0.023; mean CPM = 72.12; colony stimulating factor 3 (granulocyte)" ID="ID_938303088" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_1042276157" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF4EBP1: 1.23-fold Up; FDR = 0.0729; PValue = 0.0241; mean CPM = 40.55; eukaryotic translation initiation factor 4E binding protein 1" ID="ID_452750257" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB1: 1.23-fold Up; FDR = 0.0759; PValue = 0.0253; mean CPM = 2700; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)" ID="ID_612730270" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RXRA: 1.18-fold Down; FDR = 0.077; PValue = 0.0257; mean CPM = 35.60; retinoid X receptor, alpha" ID="ID_1367995473" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMA4: 1.2-fold Down; FDR = 0.0793; PValue = 0.0266; mean CPM = 624.4; laminin, alpha 4" ID="ID_1385576919" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF11: 1.44-fold Down; FDR = 0.0841; PValue = 0.0285; mean CPM = 3.869; fibroblast growth factor 11" ID="ID_317598575" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SGK3: 1.34-fold Up; FDR = 0.0916; PValue = 0.0316; mean CPM = 5.230; serum/glucocorticoid regulated kinase family, member 3" ID="ID_1472867339" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_385580389" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3L4: 1.3-fold Down; FDR = 0.0961; PValue = 0.0334; mean CPM = 6.034; cAMP responsive element binding protein 3-like 4" ID="ID_627333910" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRTC2: 1.18-fold Up; FDR = 0.0976; PValue = 0.0341; mean CPM = 27.36; CREB regulated transcription coactivator 2" ID="ID_530111459" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS2: 1.17-fold Up; FDR = 0.1; PValue = 0.0353; mean CPM = 31.79; son of sevenless homolog 2 (Drosophila)" ID="ID_1882814769" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3AP1: 2.18-fold Up; FDR = 0.108; PValue = 0.0384; mean CPM = 1.085; phosphoinositide-3-kinase adaptor protein 1" ID="ID_1170338157" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R5E: 1.17-fold Up; FDR = 0.112; PValue = 0.04; mean CPM = 30.87; Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform; Uncharacterized protein" ID="ID_1175993116" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_663573435" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG2: 1.64-fold Up; FDR = 0.117; PValue = 0.0421; mean CPM = 2.320; guanine nucleotide binding protein (G protein), gamma 2" ID="ID_978115465" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYB: 1.85-fold Down; FDR = 0.12; PValue = 0.0437; mean CPM = 1.320; v-myb myeloblastosis viral oncogene homolog (avian)" ID="ID_600711679" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND1: 1.17-fold Up; FDR = 0.121; PValue = 0.0443; mean CPM = 867.3; cyclin D1" ID="ID_353221771" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3: 1.15-fold Up; FDR = 0.128; PValue = 0.0472; mean CPM = 167.9; cAMP responsive element binding protein 3" ID="ID_1442956661" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IBSP: 2.51-fold Down; FDR = 0.128; PValue = 0.0476; mean CPM = 0.8896; integrin-binding sialoprotein" ID="ID_261085523" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_707587701" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGFR1: 1.15-fold Down; FDR = 0.139; PValue = 0.0525; mean CPM = 89.41; fibroblast growth factor receptor 1" ID="ID_1705796914" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG3: 1.6-fold Down; FDR = 0.155; PValue = 0.0601; mean CPM = 1.706; guanine nucleotide binding protein (G protein), gamma 3" ID="ID_1138565927" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="YWHAG: 1.14-fold Down; FDR = 0.162; PValue = 0.0632; mean CPM = 175.7; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide" ID="ID_136231177" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTEN: 1.14-fold Up; FDR = 0.166; PValue = 0.065; mean CPM = 89.60; phosphatase and tensin homolog" ID="ID_1522669659" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VWF: 1.42-fold Down; FDR = 0.174; PValue = 0.069; mean CPM = 24.05; von Willebrand factor" ID="ID_232203728" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF23: 2.01-fold Down; FDR = 0.188; PValue = 0.0759; mean CPM = 0.9718; fibroblast growth factor 23" ID="ID_1725434082" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHEB: 1.13-fold Up; FDR = 0.193; PValue = 0.0785; mean CPM = 118.9; Ras homolog enriched in brain" ID="ID_371800674" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TEK: 1.58-fold Down; FDR = 0.196; PValue = 0.0803; mean CPM = 2.573; TEK tyrosine kinase, endothelial" ID="ID_1740380447" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1415924656" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KITLG: 1.31-fold Up; FDR = 0.209; PValue = 0.0867; mean CPM = 5.766; KIT ligand" ID="ID_1568672129" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="YWHAQ: 1.13-fold Up; FDR = 0.216; PValue = 0.0903; mean CPM = 187.3; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide" ID="ID_647366934" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SGK2: 2.06-fold Down; FDR = 0.225; PValue = 0.0952; mean CPM = 0.9494; serum/glucocorticoid regulated kinase 2" ID="ID_803342280" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB4: 1.81-fold Down; FDR = 0.237; PValue = 0.101; mean CPM = 1.043; laminin, beta 4" ID="ID_198016324" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTCP1: 1.42-fold Up; FDR = 0.248; PValue = 0.107; mean CPM = 2.103; mature T-cell proliferation 1" ID="ID_245044615" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF10: 1.55-fold Down; FDR = 0.257; PValue = 0.112; mean CPM = 3.488; fibroblast growth factor 10" ID="ID_1337331889" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNE1: 1.2-fold Up; FDR = 0.278; PValue = 0.123; mean CPM = 6.609; cyclin E1" ID="ID_1485901697" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1A: 1.16-fold Down; FDR = 0.28; PValue = 0.124; mean CPM = 363.2; Cyclin-dependent kinase inhibitor 1; Uncharacterized protein" ID="ID_1685434435" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_1153834344" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NGFR: 1.72-fold Down; FDR = 0.285; PValue = 0.127; mean CPM = 1.174; nerve growth factor receptor" ID="ID_177596233" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK6: 1.18-fold Down; FDR = 0.301; PValue = 0.136; mean CPM = 26.51; cyclin-dependent kinase 6" ID="ID_1079209900" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014969: 1.93-fold Down; FDR = 0.303; PValue = 0.137; mean CPM = 0.9384; Uncharacterized protein" ID="ID_448368005" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB3: 1.6-fold Down; FDR = 0.303; PValue = 0.137; mean CPM = 1.445; laminin, beta 3" ID="ID_1802165256" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_568930102" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND2: 1.2-fold Up; FDR = 0.335; PValue = 0.155; mean CPM = 76.91; cyclin D2" ID="ID_1651077848" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL6A6: 1.78-fold Down; FDR = 0.354; PValue = 0.166; mean CPM = 0.9461; collagen, type VI, alpha 6" ID="ID_626132112" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP53: 1.11-fold Down; FDR = 0.364; PValue = 0.172; mean CPM = 33.25; tumor protein p53" ID="ID_1650678673" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG7: 1.75-fold Down; FDR = 0.366; PValue = 0.174; mean CPM = 0.9647; guanine nucleotide binding protein (G protein), gamma 7" ID="ID_940709270" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GHR: 1.23-fold Up; FDR = 0.369; PValue = 0.175; mean CPM = 6.312; growth hormone receptor" ID="ID_1188291325" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_198672429" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2: 1.48-fold Up; FDR = 0.384; PValue = 0.184; mean CPM = 1.344; Uncharacterized protein" ID="ID_252173972" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EPO: 1.77-fold Up; FDR = 0.39; PValue = 0.188; mean CPM = 0.9174; Macaca mulatta erythropoietin (EPO), mRNA." ID="ID_815725664" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R2C: 1.48-fold Up; FDR = 0.391; PValue = 0.188; mean CPM = 1.318; protein phosphatase 2, regulatory subunit B, gamma" ID="ID_1840743346" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R5C: 1.14-fold Up; FDR = 0.391; PValue = 0.189; mean CPM = 54.95; protein phosphatase 2, regulatory subunit B', gamma" ID="ID_1569605212" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2: 1.1-fold Up; FDR = 0.394; PValue = 0.191; mean CPM = 102.5; PTK2 protein tyrosine kinase 2" ID="ID_84425193" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GYS1: 1.1-fold Down; FDR = 0.405; PValue = 0.197; mean CPM = 143.6; glycogen synthase 1 (muscle)" ID="ID_638478472" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL4A3: 1.67-fold Down; FDR = 0.422; PValue = 0.207; mean CPM = 0.9315; collagen, type IV, alpha 3 (Goodpasture antigen)" ID="ID_714133030" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNN: 1.32-fold Up; FDR = 0.425; PValue = 0.209; mean CPM = 2.061; tenascin N" ID="ID_1726349782" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LPAR3: 2.49-fold Down; FDR = 0.429; PValue = 0.212; mean CPM = 0.8456; lysophosphatidic acid receptor 3" ID="ID_666046083" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RBL2: 1.09-fold Up; FDR = 0.445; PValue = 0.222; mean CPM = 47.90; retinoblastoma-like 2 (p130)" ID="ID_1274156802" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_405235726" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="F2R: 1.1-fold Up; FDR = 0.458; PValue = 0.23; mean CPM = 35.05; coagulation factor II (thrombin) receptor" ID="ID_1748222237" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000026812: 1.61-fold Down; FDR = 0.46; PValue = 0.232; mean CPM = 0.9948; Uncharacterized protein" ID="ID_908268096" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THBS4: 1.64-fold Down; FDR = 0.498; PValue = 0.257; mean CPM = 0.9543; thrombospondin 4" ID="ID_542065061" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ANGPT1: 1.13-fold Up; FDR = 0.503; PValue = 0.26; mean CPM = 28.18; angiopoietin 1" ID="ID_459315106" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VEGFB: 1.1-fold Down; FDR = 0.512; PValue = 0.267; mean CPM = 16.03; vascular endothelial growth factor B" ID="ID_827686100" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG4: 1.65-fold Down; FDR = 0.524; PValue = 0.275; mean CPM = 0.8771; guanine nucleotide binding protein (G protein), gamma 4" ID="ID_1353575927" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_127795133" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF18: 1.55-fold Down; FDR = 0.548; PValue = 0.293; mean CPM = 0.9359; fibroblast growth factor 18" ID="ID_461428469" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOXO3: 1.08-fold Down; FDR = 0.55; PValue = 0.294; mean CPM = 48.45; forkhead box O3" ID="ID_72731032" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNB1: 1.08-fold Down; FDR = 0.565; PValue = 0.305; mean CPM = 299.4; guanine nucleotide binding protein (G protein), beta polypeptide 1" ID="ID_833755078" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA1: 1.1-fold Down; FDR = 0.57; PValue = 0.308; mean CPM = 422.3; integrin, alpha 1" ID="ID_1697869493" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6: 1.08-fold Up; FDR = 0.584; PValue = 0.318; mean CPM = 892.5; ribosomal protein S6" ID="ID_999394354" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PKN1: 1.07-fold Down; FDR = 0.594; PValue = 0.325; mean CPM = 93.47; protein kinase N1" ID="ID_995187115" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA9: 1.3-fold Down; FDR = 0.595; PValue = 0.326; mean CPM = 1.685; integrin, alpha 9" ID="ID_1433748280" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EFNA5: 1.52-fold Up; FDR = 0.605; PValue = 0.334; mean CPM = 0.9602; ephrin-A5" ID="ID_853300851" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNGT2: 1.9-fold Up; FDR = 0.613; PValue = 0.339; mean CPM = 0.8227; guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2" ID="ID_1859136010" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL4A6: 1.4-fold Down; FDR = 0.631; PValue = 0.353; mean CPM = 1.078; collagen, type IV, alpha 6" ID="ID_552064563" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHRM2: 1.62-fold Down; FDR = 0.635; PValue = 0.356; mean CPM = 0.8398; cholinergic receptor, muscarinic 2" ID="ID_1239556122" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF5: 1.1-fold Down; FDR = 0.646; PValue = 0.364; mean CPM = 54.02; fibroblast growth factor 5" ID="ID_933321585" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90AB1: 1.07-fold Down; FDR = 0.652; PValue = 0.369; mean CPM = 905.8; heat shock protein 90kDa alpha (cytosolic), class B member 1" ID="ID_509512045" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VTN: 1.19-fold Up; FDR = 0.669; PValue = 0.382; mean CPM = 2.950; vitronectin" ID="ID_374355137" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNB2: 1.06-fold Down; FDR = 0.685; PValue = 0.395; mean CPM = 129.1; guanine nucleotide binding protein (G protein), beta polypeptide 2" ID="ID_1133232168" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014966: 1.43-fold Down; FDR = 0.72; PValue = 0.423; mean CPM = 0.9009; Uncharacterized protein" ID="ID_769761006" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA4: 1.16-fold Down; FDR = 0.722; PValue = 0.425; mean CPM = 5.425; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)" ID="ID_1486752465" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNB1: 1.79-fold Up; FDR = 0.731; PValue = 0.433; mean CPM = 0.8526; interferon, beta 1, fibroblast" ID="ID_488317544" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB6: 1.4-fold Down; FDR = 0.732; PValue = 0.434; mean CPM = 0.9377; Integrin beta" ID="ID_1931604036" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R2A: 1.06-fold Down; FDR = 0.733; PValue = 0.435; mean CPM = 44.53; protein phosphatase 2, regulatory subunit B, alpha" ID="ID_1716470306" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF9: 1.77-fold Up; FDR = 0.74; PValue = 0.441; mean CPM = 0.8485; fibroblast growth factor 9 (glia-activating factor)" ID="ID_1036245540" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90AA1: 1.8-fold Up; FDR = 0.749; PValue = 0.449; mean CPM = 0.8328; heat shock protein 90kDa alpha (cytosolic), class A member 1" ID="ID_808747353" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG13: 1.67-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8104; guanine nucleotide binding protein (G protein), gamma 13" ID="ID_1152399174" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF8: 1.75-fold Down; FDR = 0.783; PValue = 0.48; mean CPM = 0.8245; Uncharacterized protein" ID="ID_180628988" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="YWHAZ: 1.05-fold Down; FDR = 0.785; PValue = 0.482; mean CPM = 341.0; 14-3-3 protein zeta/delta; Uncharacterized protein" ID="ID_435284866" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREBL1: 1.05-fold Down; FDR = 0.794; PValue = 0.491; mean CPM = 64.18; activating transcription factor 6 beta" ID="ID_1097478191" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="YWHAE: 1.05-fold Up; FDR = 0.799; PValue = 0.496; mean CPM = 281.1; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide" ID="ID_959046987" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2CA: 1.05-fold Up; FDR = 0.8; PValue = 0.497; mean CPM = 62.78; protein phosphatase 2, catalytic subunit, alpha isozyme" ID="ID_415096060" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL4R: 1.05-fold Down; FDR = 0.803; PValue = 0.499; mean CPM = 193.5; interleukin 4 receptor" ID="ID_1143642049" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA6: 1.41-fold Down; FDR = 0.807; PValue = 0.504; mean CPM = 0.8019; interferon, alpha 6" ID="ID_1866307479" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF14: 1.13-fold Down; FDR = 0.809; PValue = 0.505; mean CPM = 6.007; fibroblast growth factor 14" ID="ID_1665024560" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FLT1: 1.08-fold Down; FDR = 0.849; PValue = 0.558; mean CPM = 28.21; fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)" ID="ID_311500341" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_129725202" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TCL1A: 1.28-fold Up; FDR = 0.873; PValue = 0.591; mean CPM = 0.7961; T-cell leukemia/lymphoma 1A" ID="ID_1232681219" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_132268222" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB1: 1.04-fold Up; FDR = 0.88; PValue = 0.6; mean CPM = 30.80; Uncharacterized protein" ID="ID_1055833617" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF13: 1.24-fold Up; FDR = 0.882; PValue = 0.602; mean CPM = 1.024; Fibroblast growth factor 13 isoform 1; Uncharacterized protein" ID="ID_744305016" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TCL1B: 1.29-fold Down; FDR = 0.885; PValue = 0.606; mean CPM = 0.8005; T-cell leukemia/lymphoma 1B" ID="ID_562537055" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="YWHAZ: 1.09-fold Up; FDR = 0.888; PValue = 0.61; mean CPM = 3.241; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide" ID="ID_1179787847" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK4: 1.04-fold Up; FDR = 0.899; PValue = 0.626; mean CPM = 65.45; cyclin-dependent kinase 4" ID="ID_280075486" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R2D: 1.04-fold Down; FDR = 0.899; PValue = 0.629; mean CPM = 19.98; protein phosphatase 2, regulatory subunit B, delta isoform" ID="ID_769526690" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF3: 1.22-fold Down; FDR = 0.903; PValue = 0.641; mean CPM = 0.7938; fibroblast growth factor 3 (murine mammary tumor virus integration site (v-int-2) oncogene homolog)" ID="ID_1921769268" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF17: 1.34-fold Down; FDR = 0.903; PValue = 0.662; mean CPM = 0.8230; fibroblast growth factor 17" ID="ID_188157049" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="YWHAB: 1.03-fold Up; FDR = 0.906; PValue = 0.672; mean CPM = 144.6; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide" ID="ID_1166566876" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PHLPP1: 1.03-fold Down; FDR = 0.907; PValue = 0.675; mean CPM = 21.33; PH domain and leucine rich repeat protein phosphatase 1" ID="ID_668819713" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA13: 1.13-fold Up; FDR = 0.908; PValue = 0.677; mean CPM = 0.7960; interferon, alpha 13" ID="ID_1558473199" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3L3: 1.4-fold Down; FDR = 0.908; PValue = 0.679; mean CPM = 0.8407; cAMP responsive element binding protein 3-like 3" ID="ID_98748028" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FLT4: 1.19-fold Down; FDR = 0.909; PValue = 0.689; mean CPM = 0.8780; fms-related tyrosine kinase 4" ID="ID_318169606" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LPAR4: 1.13-fold Up; FDR = 0.91; PValue = 0.693; mean CPM = 0.8442; lysophosphatidic acid receptor 4" ID="ID_1549147202" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA8: 1.13-fold Down; FDR = 0.911; PValue = 0.702; mean CPM = 0.7910; interferon, alpha 8" ID="ID_1864432786" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHRM1: 1.17-fold Up; FDR = 0.916; PValue = 0.717; mean CPM = 0.9294; cholinergic receptor, muscarinic 1" ID="ID_851835113" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSF3R: 1.13-fold Down; FDR = 0.921; PValue = 0.723; mean CPM = 0.9331; colony stimulating factor 3 receptor (granulocyte)" ID="ID_1291931305" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF19: 1.33-fold Down; FDR = 0.921; PValue = 0.724; mean CPM = 0.8101; fibroblast growth factor 19" ID="ID_368944517" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="G6PC: 1.22-fold Down; FDR = 0.929; PValue = 0.737; mean CPM = 0.8105; glucose-6-phosphatase, catalytic subunit" ID="ID_518602720" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL4: 1.27-fold Down; FDR = 0.933; PValue = 0.745; mean CPM = 0.8077; interleukin 4" ID="ID_242082370" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FASLG: 1.2-fold Down; FDR = 0.941; PValue = 0.757; mean CPM = 0.8088; Fas ligand (TNF superfamily, member 6)" ID="ID_1712695977" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2RA: 1.08-fold Up; FDR = 0.945; PValue = 0.766; mean CPM = 0.8493; interleukin 2 receptor, alpha" ID="ID_297047485" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_779223117" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF6: 1.15-fold Up; FDR = 0.948; PValue = 0.773; mean CPM = 0.8082; fibroblast growth factor 6" ID="ID_637769524" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG5: 1.02-fold Down; FDR = 0.952; PValue = 0.781; mean CPM = 21.93; guanine nucleotide binding protein (G protein), gamma 5" ID="ID_1385354646" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNE2: 1.05-fold Up; FDR = 0.962; PValue = 0.796; mean CPM = 6.415; cyclin E2" ID="ID_310010766" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA14: 1.22-fold Up; FDR = 0.965; PValue = 0.802; mean CPM = 0.8654; interferon, alpha 14" ID="ID_1191576195" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_1861868837" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA4: 1.28-fold Down; FDR = 0.983; PValue = 0.829; mean CPM = 0.8584; interferon, alpha 4" ID="ID_1361764977" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG8: 1.11-fold Down; FDR = 0.989; PValue = 0.84; mean CPM = 0.8494; guanine nucleotide binding protein (G protein), gamma 8" ID="ID_1231141645" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LPAR2: 1.06-fold Up; FDR = 0.989; PValue = 0.84; mean CPM = 1.309; lysophosphatidic acid receptor 2" ID="ID_1263793171" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNGT1: 1.05-fold Up; FDR = 1; PValue = 0.871; mean CPM = 0.8362; guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1" ID="ID_1970398263" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL11A2: 1.03-fold Down; FDR = 1; PValue = 0.872; mean CPM = 2.131; collagen, type XI, alpha 2" ID="ID_913270755" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNB5: 1.04-fold Down; FDR = 1; PValue = 0.881; mean CPM = 1.533; guanine nucleotide binding protein (G protein), beta 5" ID="ID_1636294581" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFRB: 1.01-fold Up; FDR = 1; PValue = 0.883; mean CPM = 391.1; platelet-derived growth factor receptor, beta polypeptide" ID="ID_1885147998" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGF: 1.06-fold Down; FDR = 1; PValue = 0.885; mean CPM = 0.8917; epidermal growth factor" ID="ID_277660485" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRLR: 1.06-fold Down; FDR = 1; PValue = 0.889; mean CPM = 1.017; prolactin receptor" ID="ID_1447754270" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL24A1: 1.04-fold Up; FDR = 1; PValue = 0.898; mean CPM = 1.201; collagen, type XXIV, alpha 1" ID="ID_980968364" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R5B: 1.01-fold Down; FDR = 1; PValue = 0.898; mean CPM = 92.91; protein phosphatase 2, regulatory subunit B', beta" ID="ID_1290877987" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL3: 1.17-fold Down; FDR = 1; PValue = 0.9; mean CPM = 0.8325; Macaca mulatta interleukin 3 (colony-stimulating factor, multiple) (IL3), mRNA." ID="ID_1773484764" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP9: 1.01-fold Up; FDR = 1; PValue = 0.908; mean CPM = 19.86; caspase 9, apoptosis-related cysteine peptidase" ID="ID_1787432948" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNXB: 1.03-fold Up; FDR = 1; PValue = 0.909; mean CPM = 1.078; tenascin XB" ID="ID_294048034" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="YWHAE: 1.03-fold Up; FDR = 1; PValue = 0.911; mean CPM = 1.303; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon" ID="ID_190292495" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STK11: 1.01-fold Up; FDR = 1; PValue = 0.918; mean CPM = 47.98; serine/threonine kinase 11" ID="ID_824595589" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD19: 1.15-fold Up; FDR = 1; PValue = 0.922; mean CPM = 0.8554; CD19 molecule" ID="ID_1084641573" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOS3: 1.02-fold Down; FDR = 1; PValue = 0.926; mean CPM = 1.238; nitric oxide synthase 3 (endothelial cell)" ID="ID_911326015" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THEM4: 1.01-fold Up; FDR = 1; PValue = 0.951; mean CPM = 8.571; thioesterase superfamily member 4" ID="ID_1251364813" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PCK1: 1.05-fold Down; FDR = 1; PValue = 0.961; mean CPM = 0.8008; phosphoenolpyruvate carboxykinase 1 (soluble)" ID="ID_312372945" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB7: 1.01-fold Down; FDR = 1; PValue = 0.968; mean CPM = 2.025; integrin, beta 7" ID="ID_307399831" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SYK: 1.11-fold Up; FDR = 1; PValue = 0.977; mean CPM = 0.8420; spleen tyrosine kinase" ID="ID_1950791723" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GYS2: 1.01-fold Down; FDR = 1; PValue = 0.983; mean CPM = 0.7991; glycogen synthase 2 (liver)" ID="ID_1088362475" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNR: 1.08-fold Down; FDR = 1; PValue = 0.984; mean CPM = 0.8556; tenascin R (restrictin, janusin)" ID="ID_1574062460" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R3A: No Change; FDR = 1; PValue = 0.988; mean CPM = 15.16; protein phosphatase 2 (formerly 2A), regulatory subunit B'', alpha" ID="ID_896567683" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FIGF: 1.07-fold Up; FDR = 1; PValue = 0.995; mean CPM = 0.8037; c-fos induced growth factor (vascular endothelial growth factor D)" ID="ID_174134759" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF4E1B: No Change; FDR = 1; PValue = 0.997; mean CPM = 0.7963; eukaryotic translation initiation factor 4E family member 1B" ID="ID_944835476" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2: 1.03-fold Up; FDR = 1; PValue = 0.998; mean CPM = 0.7974; interleukin 2" ID="ID_1053799172" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA1: No Change; FDR = 1; PValue = 0.998; mean CPM = 0.8014; interferon, alpha 1" ID="ID_1423692582" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="G6PC2: No Change; FDR = 1; PValue = 1; mean CPM = 0.7816; glucose-6-phosphatase, catalytic, 2" ID="ID_1769153870" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF20: No Change; FDR = 1; PValue = 1; mean CPM = 0.7796; fibroblast growth factor 20" ID="ID_1508880510" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg MicroRNAs in cancer: Inhibited, FDR = 0.00212, FWER = 0.0233, PValue = 0.000161" ID="ID_746077686" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="ITGA5: 3.79-fold Down; FDR = 1.33e-14; PValue = 1.48e-16; mean CPM = 1237; integrin, alpha 5 (fibronectin receptor, alpha polypeptide)" ID="ID_1049073261" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFRA: 2.76-fold Up; FDR = 3.93e-14; PValue = 4.67e-16; mean CPM = 492.9; platelet-derived growth factor receptor, alpha polypeptide" ID="ID_1295824482" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOTCH3: 6.31-fold Down; FDR = 2.33e-13; PValue = 3.29e-15; mean CPM = 185.7; Notch homolog 3 (Drosophila)" ID="ID_1852430255" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MET: 2.57-fold Up; FDR = 3.56e-13; PValue = 5.22e-15; mean CPM = 242.4; Macaca mulatta met proto-oncogene (hepatocyte growth factor receptor) (MET), mRNA." ID="ID_1567377118" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC4: 7.09-fold Down; FDR = 1.82e-12; PValue = 3.1e-14; mean CPM = 6.421; SHC (Src homology 2 domain containing) family, member 4" ID="ID_1511267933" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_746585215" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DNMT3A: 1.93-fold Down; FDR = 6.31e-11; PValue = 1.58e-12; mean CPM = 20.49; DNA (cytosine-5-)-methyltransferase 3 alpha" ID="ID_1900299344" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLAU: 3.37-fold Down; FDR = 1.56e-10; PValue = 4.33e-12; mean CPM = 18.78; plasminogen activator, urokinase" ID="ID_984692032" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ABCB1: 1.96-fold Up; FDR = 1.07e-09; PValue = 3.66e-11; mean CPM = 177.0; Macaca mulatta ATP-binding cassette, sub-family B (MDR/TAP), member 1 (ABCB1), mRNA." ID="ID_1435690998" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB3: 5.02-fold Down; FDR = 1.72e-09; PValue = 6.17e-11; mean CPM = 43.21; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)" ID="ID_1008791239" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_661479401" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGFR: 1.84-fold Up; FDR = 6.71e-09; PValue = 2.77e-10; mean CPM = 68.58; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)" ID="ID_390104344" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRS1: 2.78-fold Up; FDR = 7.67e-09; PValue = 3.19e-10; mean CPM = 26.55; Uncharacterized protein" ID="ID_862982129" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1B: 1.64-fold Up; FDR = 1.22e-08; PValue = 5.39e-10; mean CPM = 32.96; Cyclin-dependent kinase inhibitor 1B; Uncharacterized protein" ID="ID_244988589" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EZH2: 2.05-fold Up; FDR = 4.94e-08; PValue = 2.57e-09; mean CPM = 24.23; enhancer of zeste homolog 2 (Drosophila)" ID="ID_1513399392" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOX4: 3.14-fold Down; FDR = 9.83e-08; PValue = 5.46e-09; mean CPM = 17.55; SRY (sex determining region Y)-box 4" ID="ID_206144531" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFA: 1.92-fold Down; FDR = 2.56e-07; PValue = 1.58e-08; mean CPM = 22.99; platelet-derived growth factor alpha polypeptide" ID="ID_1747002291" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_1775325799" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNC: 1.97-fold Down; FDR = 4.07e-07; PValue = 2.63e-08; mean CPM = 2667; tenascin C" ID="ID_1021952892" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1736574409" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1127593723" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THBS1: 2.74-fold Down; FDR = 1.68e-06; PValue = 1.28e-07; mean CPM = 25785; thrombospondin 1" ID="ID_1297637987" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGFR3: 3.85-fold Down; FDR = 2.66e-06; PValue = 2.13e-07; mean CPM = 2.800; fibroblast growth factor receptor 3" ID="ID_858240271" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP16: 1.93-fold Down; FDR = 6.34e-06; PValue = 5.64e-07; mean CPM = 13.80; matrix metallopeptidase 16 (membrane-inserted)" ID="ID_1099451522" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DNMT1: 1.54-fold Down; FDR = 8.43e-06; PValue = 7.79e-07; mean CPM = 63.95; DNA (cytosine-5-)-methyltransferase 1" ID="ID_262568388" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA5: 3.28-fold Up; FDR = 1.4e-05; PValue = 1.36e-06; mean CPM = 2.288; ribosomal protein S6 kinase, 90kDa, polypeptide 5" ID="ID_1387466225" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_119154707" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DNMT3B: 2.33-fold Down; FDR = 2.54e-05; PValue = 2.64e-06; mean CPM = 2.856; DNA (cytosine-5-)-methyltransferase 3 beta" ID="ID_397612987" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DDIT4: 1.72-fold Up; FDR = 4.15e-05; PValue = 4.58e-06; mean CPM = 395.1; DNA-damage-inducible transcript 4" ID="ID_1623747063" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GLS: 1.38-fold Down; FDR = 6.41e-05; PValue = 7.53e-06; mean CPM = 95.01; Uncharacterized protein" ID="ID_63041037" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZEB2: 1.38-fold Up; FDR = 6.66e-05; PValue = 7.87e-06; mean CPM = 234.5; zinc finger E-box binding homeobox 2" ID="ID_489295921" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNG1: 1.38-fold Up; FDR = 6.77e-05; PValue = 8.01e-06; mean CPM = 149.9; cyclin G1" ID="ID_1545394147" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HMOX1: 1.94-fold Up; FDR = 7.83e-05; PValue = 9.42e-06; mean CPM = 15.01; heme oxygenase (decycling) 1" ID="ID_1865149681" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDCD4: 1.38-fold Up; FDR = 0.000119; PValue = 1.5e-05; mean CPM = 39.33; programmed cell death 4 (neoplastic transformation inhibitor)" ID="ID_1543092775" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCE: 1.73-fold Up; FDR = 0.00013; PValue = 1.67e-05; mean CPM = 10.87; protein kinase C, epsilon" ID="ID_773421844" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VIM: 1.54-fold Down; FDR = 0.000219; PValue = 3.01e-05; mean CPM = 3996; vimentin" ID="ID_1675540919" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BMF: 4.28-fold Down; FDR = 0.000248; PValue = 3.48e-05; mean CPM = 1.872; Bcl2 modifying factor" ID="ID_1816201971" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTGS2: 2.02-fold Up; FDR = 0.000254; PValue = 3.59e-05; mean CPM = 314.5; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)" ID="ID_457537478" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VEGFA: 1.47-fold Up; FDR = 0.000317; PValue = 4.59e-05; mean CPM = 463.7; vascular endothelial growth factor A" ID="ID_664271068" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EZR: 1.32-fold Up; FDR = 0.00112; PValue = 0.000192; mean CPM = 426.3; Uncharacterized protein" ID="ID_643865363" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP9: 4.49-fold Down; FDR = 0.00222; PValue = 0.000419; mean CPM = 6.597; matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)" ID="ID_846457755" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHOA: 1.28-fold Down; FDR = 0.00295; PValue = 0.000575; mean CPM = 277.8; ras homolog gene family, member A" ID="ID_1759733705" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOTCH1: 1.44-fold Down; FDR = 0.0032; PValue = 0.000634; mean CPM = 32.99; Notch homolog 1, translocation-associated (Drosophila)" ID="ID_1818538873" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BRCA1: 1.38-fold Up; FDR = 0.00331; PValue = 0.000658; mean CPM = 39.12; Macaca mulatta breast cancer 1, early onset (BRCA1), mRNA." ID="ID_547587924" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG1: 1.31-fold Down; FDR = 0.00352; PValue = 0.000707; mean CPM = 53.66; phospholipase C, gamma 1" ID="ID_1466227025" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC4: 1.38-fold Down; FDR = 0.00526; PValue = 0.00112; mean CPM = 48.60; histone deacetylase 4" ID="ID_1367906890" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MDM2: 1.32-fold Up; FDR = 0.00555; PValue = 0.00119; mean CPM = 148.6; Uncharacterized protein" ID="ID_262736233" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BMI1: 1.45-fold Up; FDR = 0.00813; PValue = 0.00185; mean CPM = 24.38; BMI1 polycomb ring finger oncogene" ID="ID_1756882932" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RECK: 1.35-fold Down; FDR = 0.00996; PValue = 0.00234; mean CPM = 48.65; reversion-inducing-cysteine-rich protein with kazal motifs" ID="ID_1652613580" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZFPM2: 2.58-fold Down; FDR = 0.0118; PValue = 0.00285; mean CPM = 1.638; zinc finger protein, multitype 2" ID="ID_750965407" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFB: 1.97-fold Down; FDR = 0.0133; PValue = 0.00326; mean CPM = 2.424; platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)" ID="ID_1159193799" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC1: 1.25-fold Up; FDR = 0.0159; PValue = 0.00403; mean CPM = 27.51; histone deacetylase 1" ID="ID_3607571" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC7A1: 1.25-fold Down; FDR = 0.0184; PValue = 0.00478; mean CPM = 113.4; solute carrier family 7 (cationic amino acid transporter, y+ system), member 1" ID="ID_591564544" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_807063935" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIM1: 1.39-fold Down; FDR = 0.0325; PValue = 0.00926; mean CPM = 21.11; pim-1 oncogene" ID="ID_1129663953" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MCL1: 1.2-fold Up; FDR = 0.0335; PValue = 0.00961; mean CPM = 193.8; myeloid cell leukemia sequence 1 (BCL2-related)" ID="ID_1870300073" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HNRNPK: 1.21-fold Up; FDR = 0.0365; PValue = 0.0106; mean CPM = 523.9; heterogeneous nuclear ribonucleoprotein K" ID="ID_665182004" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_464122374" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KRAS: 1.35-fold Down; FDR = 0.0401; PValue = 0.0119; mean CPM = 13.10; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog" ID="ID_1256589506" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZEB1: 1.27-fold Up; FDR = 0.0405; PValue = 0.012; mean CPM = 45.24; zinc finger E-box binding homeobox 1" ID="ID_20780073" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="E2F1: 1.44-fold Down; FDR = 0.0425; PValue = 0.0127; mean CPM = 8.857; E2F transcription factor 1" ID="ID_398763865" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APC2: 1.29-fold Down; FDR = 0.0505; PValue = 0.0155; mean CPM = 8.899; adenomatosis polyposis coli 2" ID="ID_773331207" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NRAS: 1.2-fold Down; FDR = 0.0546; PValue = 0.017; mean CPM = 32.39; neuroblastoma RAS viral (v-ras) oncogene homolog" ID="ID_1078959119" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP63: 1.81-fold Down; FDR = 0.0567; PValue = 0.0179; mean CPM = 2.228; tumor protein p63" ID="ID_1797037569" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L11: 1.34-fold Up; FDR = 0.0609; PValue = 0.0195; mean CPM = 18.38; BCL2-like 11 (apoptosis facilitator)" ID="ID_1107649967" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_940139920" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_35787181" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK4: 1.21-fold Down; FDR = 0.0756; PValue = 0.0252; mean CPM = 16.78; p21 protein (Cdc42/Rac)-activated kinase 4" ID="ID_1371351224" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GLS2: 1.52-fold Down; FDR = 0.0901; PValue = 0.031; mean CPM = 2.293; glutaminase 2 (liver, mitochondrial)" ID="ID_1012590187" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS2: 1.17-fold Up; FDR = 0.1; PValue = 0.0353; mean CPM = 31.79; son of sevenless homolog 2 (Drosophila)" ID="ID_1035733868" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_1501980987" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND1: 1.17-fold Up; FDR = 0.121; PValue = 0.0443; mean CPM = 867.3; cyclin D1" ID="ID_1753822420" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRIM71: 2.46-fold Down; FDR = 0.127; PValue = 0.0468; mean CPM = 0.8846; tripartite motif-containing 71" ID="ID_1004398016" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTEN: 1.14-fold Up; FDR = 0.166; PValue = 0.065; mean CPM = 89.60; phosphatase and tensin homolog" ID="ID_693469935" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RDX: 1.14-fold Up; FDR = 0.168; PValue = 0.066; mean CPM = 58.63; radixin" ID="ID_1277827926" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC45A3: 2.12-fold Down; FDR = 0.171; PValue = 0.0675; mean CPM = 1.032; Solute carrier family 45 member 3; Uncharacterized protein" ID="ID_422835303" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SIRT1: 1.17-fold Up; FDR = 0.182; PValue = 0.0729; mean CPM = 15.83; sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae)" ID="ID_196152536" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_283922244" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT3A: 2.28-fold Down; FDR = 0.2; PValue = 0.0823; mean CPM = 0.8811; wingless-type MMTV integration site family, member 3A" ID="ID_1331249214" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_1483954534" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ERBB2: 1.14-fold Down; FDR = 0.23; PValue = 0.0977; mean CPM = 119.0; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)" ID="ID_67447332" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DICER1: 1.13-fold Up; FDR = 0.261; PValue = 0.114; mean CPM = 80.31; dicer 1, ribonuclease type III" ID="ID_1746760778" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNE1: 1.2-fold Up; FDR = 0.278; PValue = 0.123; mean CPM = 6.609; cyclin E1" ID="ID_1185316209" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1A: 1.16-fold Down; FDR = 0.28; PValue = 0.124; mean CPM = 363.2; Cyclin-dependent kinase inhibitor 1; Uncharacterized protein" ID="ID_1873560188" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK6: 1.18-fold Down; FDR = 0.301; PValue = 0.136; mean CPM = 26.51; cyclin-dependent kinase 6" ID="ID_1550159560" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT3: 1.4-fold Up; FDR = 0.304; PValue = 0.138; mean CPM = 1.843; wingless-type MMTV integration site family, member 3" ID="ID_1395436994" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND2: 1.2-fold Up; FDR = 0.335; PValue = 0.155; mean CPM = 76.91; cyclin D2" ID="ID_895936657" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP53: 1.11-fold Down; FDR = 0.364; PValue = 0.172; mean CPM = 33.25; tumor protein p53" ID="ID_855841483" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APC: 1.1-fold Down; FDR = 0.367; PValue = 0.174; mean CPM = 127.5; adenomatous polyposis coli" ID="ID_1301703781" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRKL: 1.11-fold Up; FDR = 0.371; PValue = 0.176; mean CPM = 34.10; v-crk sarcoma virus CT10 oncogene homolog (avian)-like" ID="ID_1616959184" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2: 1.48-fold Up; FDR = 0.384; PValue = 0.184; mean CPM = 1.344; Uncharacterized protein" ID="ID_1423739204" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNN: 1.32-fold Up; FDR = 0.425; PValue = 0.209; mean CPM = 2.061; tenascin N" ID="ID_1852227272" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HOXD10: 1.48-fold Down; FDR = 0.435; PValue = 0.216; mean CPM = 1.820; homeobox D10" ID="ID_1338328646" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOTCH2: 1.09-fold Down; FDR = 0.514; PValue = 0.268; mean CPM = 795.0; Notch homolog 2 (Drosophila)" ID="ID_1533138067" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPRY2: 1.09-fold Down; FDR = 0.515; PValue = 0.269; mean CPM = 27.90; sprouty homolog 2 (Drosophila)" ID="ID_655680297" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L2: 1.08-fold Down; FDR = 0.578; PValue = 0.314; mean CPM = 35.23; BCL2-like 2" ID="ID_388375575" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF2BP1: 1.46-fold Down; FDR = 0.604; PValue = 0.333; mean CPM = 0.9575; insulin-like growth factor 2 mRNA binding protein 1" ID="ID_1578695558" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCG: 1.47-fold Down; FDR = 0.609; PValue = 0.336; mean CPM = 0.9297; protein kinase C, gamma" ID="ID_749186387" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MDM4: 1.07-fold Up; FDR = 0.632; PValue = 0.354; mean CPM = 28.16; Mdm4 p53 binding protein homolog (mouse)" ID="ID_240533060" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STMN1: 1.15-fold Down; FDR = 0.684; PValue = 0.395; mean CPM = 43.13; Stathmin" ID="ID_107307182" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SERPINB5: 1.44-fold Down; FDR = 0.716; PValue = 0.42; mean CPM = 0.8736; Peptidase inhibitor 5; Uncharacterized protein" ID="ID_1516834918" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCB: 1.86-fold Up; FDR = 0.727; PValue = 0.43; mean CPM = 0.8705; protein kinase C, beta" ID="ID_627285966" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="E2F3: 1.08-fold Up; FDR = 0.751; PValue = 0.452; mean CPM = 11.79; E2F transcription factor 3" ID="ID_636109039" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_492924780" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRK: 1.05-fold Up; FDR = 0.791; PValue = 0.488; mean CPM = 59.92; v-crk sarcoma virus CT10 oncogene homolog (avian)" ID="ID_572126033" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDC25A: 1.07-fold Down; FDR = 0.814; PValue = 0.511; mean CPM = 10.16; cell division cycle 25 homolog A (S. pombe)" ID="ID_700063153" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_283639390" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK7: 1.04-fold Down; FDR = 0.899; PValue = 0.632; mean CPM = 16.93; Uncharacterized protein" ID="ID_1841323235" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB2: 1.05-fold Down; FDR = 0.903; PValue = 0.655; mean CPM = 110.8; transforming growth factor, beta 2" ID="ID_1062098793" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDC25C: 1.07-fold Up; FDR = 0.911; PValue = 0.702; mean CPM = 6.242; Uncharacterized protein" ID="ID_203733794" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_1455170509" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNE2: 1.05-fold Up; FDR = 0.962; PValue = 0.796; mean CPM = 6.415; cyclin E2" ID="ID_114834998" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG2: 1.06-fold Up; FDR = 0.985; PValue = 0.834; mean CPM = 2.248; phospholipase C, gamma 2 (phosphatidylinositol-specific)" ID="ID_642080461" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ERBB3: 1.05-fold Up; FDR = 0.999; PValue = 0.856; mean CPM = 1.467; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)" ID="ID_32654714" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASSF1: 1.01-fold Down; FDR = 1; PValue = 0.87; mean CPM = 87.09; Uncharacterized protein" ID="ID_1513000520" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFRB: 1.01-fold Up; FDR = 1; PValue = 0.883; mean CPM = 391.1; platelet-derived growth factor receptor, beta polypeptide" ID="ID_1775989790" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD3: 1.03-fold Up; FDR = 1; PValue = 0.903; mean CPM = 1.636; frizzled homolog 3 (Drosophila)" ID="ID_1916726890" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="E2F2: 1.03-fold Up; FDR = 1; PValue = 0.906; mean CPM = 1.976; E2F transcription factor 2" ID="ID_214717200" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNXB: 1.03-fold Up; FDR = 1; PValue = 0.909; mean CPM = 1.078; tenascin XB" ID="ID_536796167" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BMPR2: No Change; FDR = 1; PValue = 0.974; mean CPM = 136.9; Bone morphogenetic protein receptor type-2; Uncharacterized protein" ID="ID_1799038331" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HMGA2: 1.01-fold Up; FDR = 1; PValue = 0.974; mean CPM = 2.678; high mobility group AT-hook 2" ID="ID_1661779505" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD44: No Change; FDR = 1; PValue = 0.981; mean CPM = 487.7; CD44 molecule (Indian blood group)" ID="ID_1932059843" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNR: 1.08-fold Down; FDR = 1; PValue = 0.984; mean CPM = 0.8556; tenascin R (restrictin, janusin)" ID="ID_521580887" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Axon guidance: Inhibited, FDR = 0.00238, FWER = 0.0286, PValue = 0.000197" ID="ID_1621937425" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="EPHA2: 2.06-fold Down; FDR = 4.54e-12; PValue = 8.63e-14; mean CPM = 77.86; EPH receptor A2" ID="ID_872387230" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SEMA3E: 7.8-fold Up; FDR = 6.86e-12; PValue = 1.38e-13; mean CPM = 7.345; sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E" ID="ID_899849515" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC4: 1.85-fold Down; FDR = 1.13e-11; PValue = 2.37e-13; mean CPM = 51.58; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4" ID="ID_976690889" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SEMA3F: 2.24-fold Up; FDR = 9.31e-11; PValue = 2.4e-12; mean CPM = 165.9; sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F" ID="ID_351338702" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EPHB4: 1.82-fold Down; FDR = 7.44e-10; PValue = 2.45e-11; mean CPM = 45.98; EPH receptor B4" ID="ID_1299016072" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EPHB6: 3.9-fold Down; FDR = 1.5e-09; PValue = 5.27e-11; mean CPM = 10.68; EPH receptor B6" ID="ID_1258594779" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CFL2: 1.88-fold Down; FDR = 1.06e-08; PValue = 4.59e-10; mean CPM = 58.30; cofilin 2 (muscle)" ID="ID_1543548936" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLIT2: 1.8-fold Up; FDR = 1.46e-08; PValue = 6.65e-10; mean CPM = 137.9; Uncharacterized protein" ID="ID_81089685" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SEMA3C: 2.12-fold Down; FDR = 2.31e-08; PValue = 1.1e-09; mean CPM = 443.1; sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C" ID="ID_1282287705" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EFNB2: 5.69-fold Down; FDR = 5.88e-08; PValue = 3.12e-09; mean CPM = 2.748; ephrin-B2" ID="ID_1714113229" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RGS3: 1.8-fold Down; FDR = 7.86e-08; PValue = 4.28e-09; mean CPM = 23.82; Uncharacterized protein" ID="ID_1792686880" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EFNA4: 3.75-fold Down; FDR = 2.37e-07; PValue = 1.45e-08; mean CPM = 2.749; ephrin-A4" ID="ID_1777735758" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLXNB1: 1.87-fold Down; FDR = 2.6e-07; PValue = 1.6e-08; mean CPM = 41.31; plexin B1" ID="ID_1276741032" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SEMA4B: 1.64-fold Up; FDR = 5.96e-07; PValue = 4.03e-08; mean CPM = 31.42; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B" ID="ID_1707748899" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLXNC1: 1.93-fold Up; FDR = 9.86e-07; PValue = 7.14e-08; mean CPM = 12.72; plexin C1" ID="ID_1806920303" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC3: 1.68-fold Down; FDR = 2.72e-06; PValue = 2.19e-07; mean CPM = 13.98; ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)" ID="ID_978774392" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EPHA3: 2.14-fold Up; FDR = 2.74e-06; PValue = 2.21e-07; mean CPM = 23.99; EPH receptor A3" ID="ID_244512015" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="UNC5B: 1.86-fold Down; FDR = 3.13e-06; PValue = 2.55e-07; mean CPM = 72.33; unc-5 homolog B (C. elegans)" ID="ID_1972216372" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SEMA3D: 1.88-fold Down; FDR = 5.58e-06; PValue = 4.87e-07; mean CPM = 14.63; sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D" ID="ID_464085618" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHOD: 1.47-fold Down; FDR = 4.68e-05; PValue = 5.27e-06; mean CPM = 24.82; ras homolog gene family, member D" ID="ID_332294422" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAI1: 1.47-fold Up; FDR = 5.94e-05; PValue = 6.9e-06; mean CPM = 97.19; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1" ID="ID_734529894" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLXNA3: 1.48-fold Down; FDR = 0.000155; PValue = 2.03e-05; mean CPM = 87.39; Uncharacterized protein" ID="ID_204833274" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SEMA4D: 3.57-fold Up; FDR = 0.000268; PValue = 3.79e-05; mean CPM = 1.557; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D" ID="ID_1730449353" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP3CA: 1.55-fold Up; FDR = 0.0003; PValue = 4.32e-05; mean CPM = 40.21; protein phosphatase 3, catalytic subunit, alpha isozyme" ID="ID_1327424587" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC2: 4.03-fold Down; FDR = 0.000346; PValue = 5.06e-05; mean CPM = 1.347; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2" ID="ID_107238807" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EPHB3: 3.8-fold Down; FDR = 0.00036; PValue = 5.3e-05; mean CPM = 4.151; EPH receptor B3" ID="ID_822121081" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCK1: 1.39-fold Up; FDR = 0.000442; PValue = 6.67e-05; mean CPM = 21.55; NCK adaptor protein 1" ID="ID_1600655708" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SRGAP1: 1.59-fold Up; FDR = 0.000551; PValue = 8.56e-05; mean CPM = 31.45; Uncharacterized protein" ID="ID_985206997" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NRP1: 1.48-fold Up; FDR = 0.000563; PValue = 8.76e-05; mean CPM = 54.61; neuropilin 1" ID="ID_1384728719" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCR4: 4.65-fold Down; FDR = 0.00226; PValue = 0.000426; mean CPM = 2.073; chemokine (C-X-C motif) receptor 4" ID="ID_648582346" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK3: 3.55-fold Up; FDR = 0.00273; PValue = 0.000527; mean CPM = 1.136; p21 protein (Cdc42/Rac)-activated kinase 3" ID="ID_1297244824" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHOA: 1.28-fold Down; FDR = 0.00295; PValue = 0.000575; mean CPM = 277.8; ras homolog gene family, member A" ID="ID_1620301610" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EFNA2: 4.72-fold Down; FDR = 0.00348; PValue = 0.000699; mean CPM = 1.248; ephrin-A2" ID="ID_238720589" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAI3: 1.26-fold Up; FDR = 0.00487; PValue = 0.00103; mean CPM = 113.8; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3" ID="ID_277425860" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LIMK2: 1.51-fold Down; FDR = 0.00509; PValue = 0.00108; mean CPM = 60.03; LIM domain kinase 2" ID="ID_1622091735" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK5: 1.31-fold Up; FDR = 0.0067; PValue = 0.00148; mean CPM = 17.46; cyclin-dependent kinase 5" ID="ID_267936813" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FES: 1.34-fold Up; FDR = 0.00677; PValue = 0.0015; mean CPM = 22.71; feline sarcoma oncogene" ID="ID_682024988" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EFNA3: 2.71-fold Down; FDR = 0.0114; PValue = 0.00271; mean CPM = 1.699; ephrin-A3" ID="ID_1573155909" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EFNA1: 2.73-fold Down; FDR = 0.0114; PValue = 0.00272; mean CPM = 1.130; ephrin-A1" ID="ID_1582702302" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NTNG1: 2.36-fold Down; FDR = 0.0143; PValue = 0.00357; mean CPM = 1.724; netrin G1" ID="ID_1083923597" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCK2: 1.25-fold Down; FDR = 0.0145; PValue = 0.0036; mean CPM = 30.56; Uncharacterized protein" ID="ID_989687261" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FYN: 1.22-fold Up; FDR = 0.0156; PValue = 0.00393; mean CPM = 92.94; FYN oncogene related to SRC, FGR, YES" ID="ID_1952086818" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EPHA1: 1.56-fold Down; FDR = 0.019; PValue = 0.00496; mean CPM = 4.328; EPH receptor A1" ID="ID_1875989887" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_718252987" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ABLIM2: 2.58-fold Up; FDR = 0.0214; PValue = 0.0057; mean CPM = 1.320; actin binding LIM protein family, member 2" ID="ID_377285246" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARHGEF12: 1.21-fold Up; FDR = 0.0298; PValue = 0.00837; mean CPM = 203.3; Rho guanine nucleotide exchange factor (GEF) 12" ID="ID_1300555871" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC2: 2.96-fold Up; FDR = 0.0309; PValue = 0.00872; mean CPM = 0.9737; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)" ID="ID_112003205" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ABLIM3: 3.1-fold Down; FDR = 0.0353; PValue = 0.0102; mean CPM = 0.8884; actin binding LIM protein family, member 3" ID="ID_217331079" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK6: 3.06-fold Down; FDR = 0.04; PValue = 0.0118; mean CPM = 0.9224; p21 protein (Cdc42/Rac)-activated kinase 6" ID="ID_1527177167" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KRAS: 1.35-fold Down; FDR = 0.0401; PValue = 0.0119; mean CPM = 13.10; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog" ID="ID_1114942418" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLXNA1: 1.2-fold Down; FDR = 0.0433; PValue = 0.013; mean CPM = 234.9; plexin A1" ID="ID_1766582612" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NRAS: 1.2-fold Down; FDR = 0.0546; PValue = 0.017; mean CPM = 32.39; neuroblastoma RAS viral (v-ras) oncogene homolog" ID="ID_1915583443" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EFNB1: 1.26-fold Down; FDR = 0.0585; PValue = 0.0185; mean CPM = 16.54; ephrin-B1" ID="ID_48456443" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EFNB3: 2.51-fold Down; FDR = 0.0671; PValue = 0.0218; mean CPM = 0.9677; Uncharacterized protein" ID="ID_1525170402" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_626672126" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK4: 1.21-fold Down; FDR = 0.0756; PValue = 0.0252; mean CPM = 16.78; p21 protein (Cdc42/Rac)-activated kinase 4" ID="ID_1858922843" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB1: 1.23-fold Up; FDR = 0.0759; PValue = 0.0253; mean CPM = 2700; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)" ID="ID_1802778735" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="UNC5A: 2.31-fold Down; FDR = 0.0987; PValue = 0.0345; mean CPM = 0.9772; unc-5 homolog A (C. elegans)" ID="ID_1592264009" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAI2: 1.15-fold Down; FDR = 0.134; PValue = 0.0501; mean CPM = 356.3; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2" ID="ID_1395615278" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK2: 1.15-fold Up; FDR = 0.134; PValue = 0.0502; mean CPM = 89.49; p21 protein (Cdc42/Rac)-activated kinase 2" ID="ID_1204223565" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_1148651120" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ROCK2: 1.14-fold Up; FDR = 0.166; PValue = 0.065; mean CPM = 247.7; Rho-associated, coiled-coil containing protein kinase 2" ID="ID_922747901" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NGEF: 1.73-fold Down; FDR = 0.191; PValue = 0.0775; mean CPM = 4.466; neuronal guanine nucleotide exchange factor" ID="ID_938143869" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EPHA4: 1.74-fold Up; FDR = 0.215; PValue = 0.0899; mean CPM = 1.516; EPH receptor A4" ID="ID_697520972" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SEMA3G: 1.61-fold Down; FDR = 0.307; PValue = 0.14; mean CPM = 1.194; sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G" ID="ID_1511089061" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2: 1.1-fold Up; FDR = 0.394; PValue = 0.191; mean CPM = 102.5; PTK2 protein tyrosine kinase 2" ID="ID_551110098" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLXNA2: 1.15-fold Up; FDR = 0.402; PValue = 0.195; mean CPM = 23.78; plexin A2" ID="ID_56968441" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SRGAP3: 1.41-fold Down; FDR = 0.415; PValue = 0.204; mean CPM = 1.959; SLIT-ROBO Rho GTPase activating protein 3" ID="ID_1134033299" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ABL1: 1.09-fold Up; FDR = 0.43; PValue = 0.213; mean CPM = 178.0; c-abl oncogene 1, receptor tyrosine kinase" ID="ID_1979156194" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_405712225" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="UNC5D: 1.67-fold Down; FDR = 0.471; PValue = 0.239; mean CPM = 0.8799; Uncharacterized protein" ID="ID_1953260706" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL12: 1.27-fold Down; FDR = 0.488; PValue = 0.251; mean CPM = 4.383; chemokine (C-X-C motif) ligand 12" ID="ID_220654895" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP3CB: 1.08-fold Up; FDR = 0.514; PValue = 0.268; mean CPM = 76.44; protein phosphatase 3, catalytic subunit, beta isozyme" ID="ID_1160896875" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RND1: 1.52-fold Down; FDR = 0.546; PValue = 0.291; mean CPM = 1.634; Rho family GTPase 1" ID="ID_1412027767" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ROBO1: 1.09-fold Up; FDR = 0.548; PValue = 0.293; mean CPM = 52.50; roundabout, axon guidance receptor, homolog 1 (Drosophila)" ID="ID_1739196644" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="L1CAM: 1.34-fold Down; FDR = 0.601; PValue = 0.331; mean CPM = 2.064; Uncharacterized protein" ID="ID_1939262360" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EFNA5: 1.52-fold Up; FDR = 0.605; PValue = 0.334; mean CPM = 0.9602; ephrin-A5" ID="ID_708497828" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDC42: 1.07-fold Down; FDR = 0.608; PValue = 0.335; mean CPM = 91.67; cell division cycle 42" ID="ID_143054351" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EPHA5: 1.57-fold Up; FDR = 0.813; PValue = 0.51; mean CPM = 0.8647; EPH receptor A5" ID="ID_282104274" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SEMA4F: 1.06-fold Down; FDR = 0.813; PValue = 0.51; mean CPM = 15.29; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F" ID="ID_1321990524" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SEMA4G: 1.13-fold Down; FDR = 0.816; PValue = 0.514; mean CPM = 2.430; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G" ID="ID_931412442" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NTN1: 1.17-fold Down; FDR = 0.834; PValue = 0.538; mean CPM = 1.642; netrin 1" ID="ID_1278118532" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="UNC5C: 1.26-fold Up; FDR = 0.897; PValue = 0.622; mean CPM = 0.8770; unc-5 homolog C (C. elegans)" ID="ID_1318749630" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ROBO3: 1.1-fold Up; FDR = 0.903; PValue = 0.643; mean CPM = 2.060; roundabout, axon guidance receptor, homolog 3 (Drosophila)" ID="ID_164934861" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EPHA6: 1.36-fold Up; FDR = 0.906; PValue = 0.668; mean CPM = 0.8455; EPH receptor A6" ID="ID_1074934553" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LRRC4C: 1.2-fold Up; FDR = 0.906; PValue = 0.671; mean CPM = 0.7955; leucine rich repeat containing 4C" ID="ID_347903072" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASA1: 1.03-fold Down; FDR = 0.909; PValue = 0.69; mean CPM = 103.7; Ras GTPase-activating protein 1 isoform 1; Uncharacterized protein" ID="ID_1593471143" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LIMK2: 1.14-fold Down; FDR = 0.911; PValue = 0.697; mean CPM = 0.7896; LIM domain kinase 2" ID="ID_1069314276" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK1: 1.03-fold Down; FDR = 0.911; PValue = 0.705; mean CPM = 18.65; p21 protein (Cdc42/Rac)-activated kinase 1" ID="ID_1838666667" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SEMA4C: 1.03-fold Down; FDR = 0.927; PValue = 0.735; mean CPM = 26.41; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C" ID="ID_1065974098" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EPHB1: 1.16-fold Down; FDR = 0.946; PValue = 0.768; mean CPM = 0.8932; EPH receptor B1" ID="ID_1181290559" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EPHA8: 1.15-fold Up; FDR = 0.949; PValue = 0.774; mean CPM = 0.9070; EPH receptor A8" ID="ID_949850819" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC3: 1.03-fold Down; FDR = 0.952; PValue = 0.78; mean CPM = 13.31; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3" ID="ID_956277549" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_269184574" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SEMA7A: 1.02-fold Down; FDR = 0.995; PValue = 0.851; mean CPM = 196.5; semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)" ID="ID_1713763991" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SEMA4A: 1.06-fold Up; FDR = 1; PValue = 0.875; mean CPM = 1.543; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A" ID="ID_1443065715" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DCC: 1.02-fold Up; FDR = 1; PValue = 0.89; mean CPM = 0.8383; deleted in colorectal carcinoma" ID="ID_420017743" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK7: 1.01-fold Up; FDR = 1; PValue = 0.923; mean CPM = 0.8495; p21 protein (Cdc42/Rac)-activated kinase 7" ID="ID_1152876911" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DPYSL2: 1.01-fold Down; FDR = 1; PValue = 0.957; mean CPM = 80.02; dihydropyrimidinase-like 2" ID="ID_1847029097" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLIT1: 1.02-fold Up; FDR = 1; PValue = 0.958; mean CPM = 1.401; slit homolog 1 (Drosophila)" ID="ID_1772785292" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EPHA7: 1.06-fold Down; FDR = 1; PValue = 0.986; mean CPM = 0.8215; EPH receptor A7" ID="ID_968690727" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Toxoplasmosis: Activated, FDR = 0.00258, FWER = 0.0335, PValue = 0.000231" ID="ID_120976872" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TLR2: 8.94-fold Up; FDR = 6.97e-23; PValue = 1.25e-25; mean CPM = 18.41; toll-like receptor 2" ID="ID_759911123" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_43149107" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_500679128" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CIITA: 45.8-fold Up; FDR = 1.14e-17; PValue = 7.44e-20; mean CPM = 27.80; class II, major histocompatibility complex, transactivator" ID="ID_383046090" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_897272573" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA2: 4.21-fold Down; FDR = 2.4e-14; PValue = 2.77e-16; mean CPM = 66.42; heat shock 70kDa protein 2" ID="ID_499284969" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMC1: 2.28-fold Down; FDR = 6.46e-13; PValue = 1.01e-14; mean CPM = 812.1; laminin, gamma 1 (formerly LAMB2)" ID="ID_132661803" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016591: 4.2-fold Down; FDR = 1.3e-11; PValue = 2.78e-13; mean CPM = 34.90; Uncharacterized protein" ID="ID_1815746417" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016587: 4.92-fold Down; FDR = 1.6e-11; PValue = 3.5e-13; mean CPM = 51.70; Uncharacterized protein" ID="ID_1056148626" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_1497198333" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC2: 1.96-fold Up; FDR = 1.01e-10; PValue = 2.62e-12; mean CPM = 53.58; baculoviral IAP repeat-containing 2" ID="ID_1809143101" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LY96: 3.13-fold Up; FDR = 1.27e-10; PValue = 3.43e-12; mean CPM = 6.127; lymphocyte antigen 96" ID="ID_384075960" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR4: 3.45-fold Up; FDR = 3.1e-09; PValue = 1.19e-10; mean CPM = 7.456; Macaca mulatta toll-like receptor 4 (TLR4), mRNA." ID="ID_416193261" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA1B: 2.24-fold Down; FDR = 4.33e-09; PValue = 1.71e-10; mean CPM = 44.90; Heat shock 70 kDa protein 1A/1B (Heat shock 70 kDa protein 1/2)(HSP70.1/HSP70.2)(HSP70-1/HSP70-2)" ID="ID_845757743" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA8: 1.64-fold Up; FDR = 1.46e-08; PValue = 6.6e-10; mean CPM = 1881; heat shock 70kDa protein 8" ID="ID_509161129" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK4: 1.8-fold Up; FDR = 3.31e-08; PValue = 1.64e-09; mean CPM = 12.89; interleukin-1 receptor-associated kinase 4" ID="ID_833759449" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1303805024" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_1024804557" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_670324288" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_662324116" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_1772339060" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC3: 2.79-fold Up; FDR = 1.74e-06; PValue = 1.32e-07; mean CPM = 95.34; baculoviral IAP repeat-containing 3" ID="ID_157341900" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_926639125" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K3: 1.45-fold Down; FDR = 7.01e-06; PValue = 6.34e-07; mean CPM = 180.1; mitogen-activated protein kinase kinase 3" ID="ID_834055384" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMC2: 2.28-fold Down; FDR = 9.83e-06; PValue = 9.24e-07; mean CPM = 16.99; laminin, gamma 2" ID="ID_332943949" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAI1: 1.47-fold Up; FDR = 5.94e-05; PValue = 6.9e-06; mean CPM = 97.19; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1" ID="ID_459468159" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP2: 1.45-fold Up; FDR = 0.000179; PValue = 2.4e-05; mean CPM = 65.31; TGF-beta activated kinase 1/MAP3K7 binding protein 2" ID="ID_1105406901" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40: 2.76-fold Up; FDR = 0.00039; PValue = 5.79e-05; mean CPM = 9.139; CD40 molecule, TNF receptor superfamily member 5" ID="ID_127471882" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB2: 1.48-fold Down; FDR = 0.000398; PValue = 5.93e-05; mean CPM = 695.6; laminin, beta 2 (laminin S)" ID="ID_1900883500" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAD: 1.36-fold Down; FDR = 0.000605; PValue = 9.52e-05; mean CPM = 48.46; BCL2-associated agonist of cell death" ID="ID_868941554" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR1: 1.31-fold Up; FDR = 0.00151; PValue = 0.000268; mean CPM = 37.77; interferon gamma receptor 1" ID="ID_1697589365" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAI3: 1.26-fold Up; FDR = 0.00487; PValue = 0.00103; mean CPM = 113.8; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3" ID="ID_435732468" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1224210703" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_1310090470" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYK2: 1.24-fold Down; FDR = 0.0142; PValue = 0.00354; mean CPM = 42.58; tyrosine kinase 2" ID="ID_59841763" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1923218509" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA6: 2.05-fold Down; FDR = 0.0226; PValue = 0.00604; mean CPM = 2.573; heat shock 70kDa protein 6 (HSP70B')" ID="ID_1497227123" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_754145384" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR2: 1.23-fold Up; FDR = 0.0258; PValue = 0.00707; mean CPM = 46.52; interferon gamma receptor 2 (interferon gamma transducer 1)" ID="ID_1577449310" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDPK1: 1.24-fold Down; FDR = 0.0361; PValue = 0.0105; mean CPM = 17.53; 3-phosphoinositide dependent protein kinase-1" ID="ID_1222015457" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1052444730" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB1: 1.23-fold Up; FDR = 0.0759; PValue = 0.0253; mean CPM = 2700; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)" ID="ID_530732816" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMA4: 1.2-fold Down; FDR = 0.0793; PValue = 0.0266; mean CPM = 624.4; laminin, alpha 4" ID="ID_1663774146" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPIF: 1.22-fold Down; FDR = 0.0887; PValue = 0.0304; mean CPM = 22.64; peptidylprolyl isomerase F" ID="ID_1105155165" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_1146758311" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_1161314259" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_1565057595" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAI2: 1.15-fold Down; FDR = 0.134; PValue = 0.0501; mean CPM = 356.3; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2" ID="ID_906717369" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XIAP: 1.17-fold Up; FDR = 0.177; PValue = 0.0706; mean CPM = 19.21; X-linked inhibitor of apoptosis" ID="ID_565034629" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XIAP: 1.26-fold Up; FDR = 0.192; PValue = 0.0778; mean CPM = 5.625; Uncharacterized protein" ID="ID_1479484294" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000039103: 1.67-fold Down; FDR = 0.221; PValue = 0.0927; mean CPM = 1.310; Uncharacterized protein" ID="ID_918569787" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB4: 1.81-fold Down; FDR = 0.237; PValue = 0.101; mean CPM = 1.043; laminin, beta 4" ID="ID_1291426626" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_1989326982" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1A: 1.11-fold Up; FDR = 0.297; PValue = 0.134; mean CPM = 134.7; tumor necrosis factor receptor superfamily, member 1A" ID="ID_507327555" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014969: 1.93-fold Down; FDR = 0.303; PValue = 0.137; mean CPM = 0.9384; Uncharacterized protein" ID="ID_1573913611" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB3: 1.6-fold Down; FDR = 0.303; PValue = 0.137; mean CPM = 1.445; laminin, beta 3" ID="ID_1353340042" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_1278054250" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP1: 1.12-fold Down; FDR = 0.351; PValue = 0.165; mean CPM = 17.96; TGF-beta activated kinase 1/MAP3K7 binding protein 1" ID="ID_1306729807" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_566438616" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_1677806549" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1131345933" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK12: 1.19-fold Down; FDR = 0.422; PValue = 0.208; mean CPM = 6.569; mitogen-activated protein kinase 12" ID="ID_1371629870" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1013478535" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR5: 1.56-fold Down; FDR = 0.487; PValue = 0.249; mean CPM = 1.064; chemokine (C-C motif) receptor 5" ID="ID_869760088" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL10RA: 1.55-fold Down; FDR = 0.516; PValue = 0.269; mean CPM = 0.9545; interleukin 10 receptor, alpha" ID="ID_991184351" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_828846178" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK13: 1.22-fold Down; FDR = 0.536; PValue = 0.284; mean CPM = 3.100; mitogen-activated protein kinase 13" ID="ID_1663845342" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014966: 1.43-fold Down; FDR = 0.72; PValue = 0.423; mean CPM = 0.9009; Uncharacterized protein" ID="ID_83808821" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_1032750382" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYCS: 1.05-fold Up; FDR = 0.854; PValue = 0.565; mean CPM = 93.43; cytochrome c, somatic" ID="ID_1436118100" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_181825942" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000040219: 1.08-fold Up; FDR = 0.86; PValue = 0.575; mean CPM = 8.818; Uncharacterized protein" ID="ID_354908775" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC7: 1.52-fold Down; FDR = 0.881; PValue = 0.601; mean CPM = 0.8439; baculoviral IAP repeat containing 7" ID="ID_1572444119" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK1: 1.04-fold Down; FDR = 0.885; PValue = 0.606; mean CPM = 41.54; interleukin-1 receptor-associated kinase 1" ID="ID_1445600032" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_8652126" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_1665365146" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000009289: 1.07-fold Up; FDR = 0.963; PValue = 0.798; mean CPM = 2.536; Uncharacterized protein" ID="ID_138515962" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_1488660647" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAO1: 1.1-fold Down; FDR = 1; PValue = 0.866; mean CPM = 0.8448; guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O" ID="ID_953284743" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP9: 1.01-fold Up; FDR = 1; PValue = 0.908; mean CPM = 19.86; caspase 9, apoptosis-related cysteine peptidase" ID="ID_1216783419" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_1515430786" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL10: 1.21-fold Down; FDR = 1; PValue = 0.964; mean CPM = 0.8614; interleukin 10" ID="ID_1885051307" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40LG: 1.01-fold Down; FDR = 1; PValue = 0.982; mean CPM = 0.8653; CD40 ligand" ID="ID_290645013" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Regulation of actin cytoskeleton: Inhibited, FDR = 0.00295, FWER = 0.0437, PValue = 0.000301" ID="ID_848327948" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="MRAS: 2.04-fold Up; FDR = 4.47e-15; PValue = 4.43e-17; mean CPM = 41.38; muscle RAS oncogene homolog" ID="ID_1509563087" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA5: 3.79-fold Down; FDR = 1.33e-14; PValue = 1.48e-16; mean CPM = 1237; integrin, alpha 5 (fibronectin receptor, alpha polypeptide)" ID="ID_261517507" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFRA: 2.76-fold Up; FDR = 3.93e-14; PValue = 4.67e-16; mean CPM = 492.9; platelet-derived growth factor receptor, alpha polypeptide" ID="ID_962111826" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VCL: 2.48-fold Down; FDR = 5.94e-13; PValue = 9.16e-15; mean CPM = 1013; vinculin" ID="ID_173427117" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAV: 2.64-fold Down; FDR = 6.04e-11; PValue = 1.51e-12; mean CPM = 337.3; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)" ID="ID_1425856756" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MSN: 1.65-fold Down; FDR = 5.3e-10; PValue = 1.68e-11; mean CPM = 571.5; moesin" ID="ID_95795557" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB8: 3.97-fold Up; FDR = 6.37e-10; PValue = 2.06e-11; mean CPM = 11.37; integrin, beta 8" ID="ID_1582557620" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA2: 2.84-fold Up; FDR = 7.38e-10; PValue = 2.42e-11; mean CPM = 176.3; integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)" ID="ID_1468217955" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB3: 5.02-fold Down; FDR = 1.72e-09; PValue = 6.17e-11; mean CPM = 43.21; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)" ID="ID_756251615" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_1722337630" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGFR: 1.84-fold Up; FDR = 6.71e-09; PValue = 2.77e-10; mean CPM = 68.58; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)" ID="ID_313822733" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB5: 1.61-fold Down; FDR = 8.23e-09; PValue = 3.47e-10; mean CPM = 471.0; integrin, beta 5" ID="ID_1783701500" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGFR2: 3.45-fold Down; FDR = 1.04e-08; PValue = 4.53e-10; mean CPM = 5.064; fibroblast growth factor receptor 2" ID="ID_833449572" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CFL2: 1.88-fold Down; FDR = 1.06e-08; PValue = 4.59e-10; mean CPM = 58.30; cofilin 2 (muscle)" ID="ID_1491242269" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA10: 4.95-fold Down; FDR = 1.77e-08; PValue = 8.13e-10; mean CPM = 5.184; integrin, alpha 10" ID="ID_880036864" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYL9: 2.18-fold Down; FDR = 2.17e-08; PValue = 1.03e-09; mean CPM = 805.4; myosin, light chain 9, regulatory" ID="ID_1958162380" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SSH1: 1.66-fold Down; FDR = 2.73e-08; PValue = 1.33e-09; mean CPM = 152.8; slingshot homolog 1 (Drosophila)" ID="ID_384834391" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA8: 4.04-fold Down; FDR = 5.89e-08; PValue = 3.12e-09; mean CPM = 145.8; integrin, alpha 8" ID="ID_780880193" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACTN4: 1.63-fold Down; FDR = 6.46e-08; PValue = 3.46e-09; mean CPM = 631.8; actinin, alpha 4" ID="ID_1465014646" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1095398007" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARHGEF7: 1.72-fold Down; FDR = 6.46e-07; PValue = 4.4e-08; mean CPM = 53.66; Rho guanine nucleotide exchange factor (GEF) 7" ID="ID_1139765017" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD14: 2.75-fold Down; FDR = 6.54e-07; PValue = 4.46e-08; mean CPM = 5.195; CD14 molecule" ID="ID_1528944458" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYLK: 2.29-fold Down; FDR = 1.02e-06; PValue = 7.45e-08; mean CPM = 128.3; myosin light chain kinase" ID="ID_903413839" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_71540574" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCKAP1L: 3.52-fold Down; FDR = 1.76e-06; PValue = 1.35e-07; mean CPM = 3.668; NCK-associated protein 1-like" ID="ID_1754992390" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGFR3: 3.85-fold Down; FDR = 2.66e-06; PValue = 2.13e-07; mean CPM = 2.800; fibroblast growth factor receptor 3" ID="ID_180592745" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC3: 1.68-fold Down; FDR = 2.72e-06; PValue = 2.19e-07; mean CPM = 13.98; ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)" ID="ID_652317862" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIP5K2A: 1.46-fold Up; FDR = 5.17e-06; PValue = 4.47e-07; mean CPM = 34.65; phosphatidylinositol-5-phosphate 4-kinase, type II, alpha" ID="ID_1147891474" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1125642566" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYH9: 1.62-fold Down; FDR = 0.000189; PValue = 2.55e-05; mean CPM = 5791; myosin, heavy chain 9, non-muscle" ID="ID_725844327" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCAR1: 1.36-fold Up; FDR = 0.000193; PValue = 2.61e-05; mean CPM = 210.4; breast cancer anti-estrogen resistance 1" ID="ID_1430261439" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WASF1: 1.64-fold Up; FDR = 0.000198; PValue = 2.69e-05; mean CPM = 8.306; WAS protein family, member 1" ID="ID_1387250046" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYL5: 2.41-fold Up; FDR = 0.000248; PValue = 3.48e-05; mean CPM = 2.729; myosin, light chain 5, regulatory" ID="ID_290990127" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA3: 1.34-fold Down; FDR = 0.000518; PValue = 7.96e-05; mean CPM = 126.8; integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)" ID="ID_594024344" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCKAP1: 1.33-fold Up; FDR = 0.000536; PValue = 8.28e-05; mean CPM = 244.8; NCK-associated protein 1" ID="ID_742428387" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DIAPH2: 1.35-fold Up; FDR = 0.000559; PValue = 8.7e-05; mean CPM = 32.86; Uncharacterized protein" ID="ID_1370023991" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SSH2: 1.42-fold Down; FDR = 0.000773; PValue = 0.000126; mean CPM = 20.79; slingshot homolog 2 (Drosophila)" ID="ID_1352094829" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNA12: 1.32-fold Down; FDR = 0.000955; PValue = 0.00016; mean CPM = 33.75; Uncharacterized protein" ID="ID_1074124871" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EZR: 1.32-fold Up; FDR = 0.00112; PValue = 0.000192; mean CPM = 426.3; Uncharacterized protein" ID="ID_1071900603" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIP4K2C: 1.39-fold Up; FDR = 0.00119; PValue = 0.000205; mean CPM = 16.06; phosphatidylinositol-5-phosphate 4-kinase, type II, gamma" ID="ID_207348171" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PFN2: 1.41-fold Up; FDR = 0.00199; PValue = 0.000369; mean CPM = 25.56; Profilin" ID="ID_1757100211" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK3: 3.55-fold Up; FDR = 0.00273; PValue = 0.000527; mean CPM = 1.136; p21 protein (Cdc42/Rac)-activated kinase 3" ID="ID_263227152" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHOA: 1.28-fold Down; FDR = 0.00295; PValue = 0.000575; mean CPM = 277.8; ras homolog gene family, member A" ID="ID_1011135008" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARHGEF1: 1.3-fold Down; FDR = 0.00297; PValue = 0.000581; mean CPM = 51.91; Rho guanine nucleotide exchange factor (GEF) 1" ID="ID_1223937032" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB4: 1.66-fold Down; FDR = 0.00369; PValue = 0.000748; mean CPM = 5.291; integrin, beta 4" ID="ID_1317388976" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP1R12B: 1.52-fold Down; FDR = 0.00383; PValue = 0.000782; mean CPM = 15.41; protein phosphatase 1, regulatory (inhibitor) subunit 12B" ID="ID_745742360" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG12: 1.31-fold Up; FDR = 0.00387; PValue = 0.000792; mean CPM = 24.97; guanine nucleotide binding protein (G protein), gamma 12" ID="ID_1189415934" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYL12B: 1.28-fold Up; FDR = 0.00408; PValue = 0.00084; mean CPM = 372.0; myosin, light chain 12B, regulatory" ID="ID_78853683" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV3: 1.82-fold Down; FDR = 0.00463; PValue = 0.000973; mean CPM = 7.044; vav 3 guanine nucleotide exchange factor" ID="ID_1923951043" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIP5K1C: 1.27-fold Down; FDR = 0.00491; PValue = 0.00104; mean CPM = 37.75; phosphatidylinositol-4-phosphate 5-kinase, type I, gamma" ID="ID_1556141522" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LIMK2: 1.51-fold Down; FDR = 0.00509; PValue = 0.00108; mean CPM = 60.03; LIM domain kinase 2" ID="ID_730211157" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARHGAP35: 1.25-fold Up; FDR = 0.00754; PValue = 0.0017; mean CPM = 176.9; Rho GTPase activating protein 35" ID="ID_343284962" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WASL: 1.26-fold Up; FDR = 0.00781; PValue = 0.00177; mean CPM = 33.90; Wiskott-Aldrich syndrome-like" ID="ID_443680462" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYL12A: 1.25-fold Up; FDR = 0.0122; PValue = 0.00294; mean CPM = 576.5; myosin, light chain 12A, regulatory, non-sarcomeric" ID="ID_911991151" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IQGAP3: 1.55-fold Down; FDR = 0.0122; PValue = 0.00296; mean CPM = 43.66; IQ motif containing GTPase activating protein 3" ID="ID_627453785" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARHGEF4: 1.88-fold Down; FDR = 0.0158; PValue = 0.00398; mean CPM = 1.968; Rho guanine nucleotide exchange factor (GEF) 4" ID="ID_692160887" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB2: 1.55-fold Down; FDR = 0.0187; PValue = 0.00485; mean CPM = 34.87; Integrin beta" ID="ID_713414436" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA2B: 1.71-fold Down; FDR = 0.0187; PValue = 0.00486; mean CPM = 2.655; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)" ID="ID_792244192" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DIAPH3: 1.5-fold Down; FDR = 0.0188; PValue = 0.00489; mean CPM = 30.74; diaphanous homolog 3 (Drosophila)" ID="ID_1537841594" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_150171449" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GIT1: 1.22-fold Down; FDR = 0.0212; PValue = 0.00564; mean CPM = 54.83; G protein-coupled receptor kinase interacting ArfGAP 1" ID="ID_713653404" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGD1: 1.29-fold Down; FDR = 0.022; PValue = 0.00588; mean CPM = 13.87; FYVE, RhoGEF and PH domain containing 1" ID="ID_1845663113" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RRAS2: 1.21-fold Up; FDR = 0.0278; PValue = 0.00771; mean CPM = 61.00; related RAS viral (r-ras) oncogene homolog 2" ID="ID_1878931966" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARHGEF12: 1.21-fold Up; FDR = 0.0298; PValue = 0.00837; mean CPM = 203.3; Rho guanine nucleotide exchange factor (GEF) 12" ID="ID_729088016" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARHGEF6: 1.3-fold Down; FDR = 0.0302; PValue = 0.00847; mean CPM = 14.09; Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6" ID="ID_1393716423" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSN: 1.22-fold Down; FDR = 0.0305; PValue = 0.0086; mean CPM = 1017; gelsolin" ID="ID_1221579395" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC2: 2.96-fold Up; FDR = 0.0309; PValue = 0.00872; mean CPM = 0.9737; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)" ID="ID_1297327369" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK6: 3.06-fold Down; FDR = 0.04; PValue = 0.0118; mean CPM = 0.9224; p21 protein (Cdc42/Rac)-activated kinase 6" ID="ID_1585140445" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KRAS: 1.35-fold Down; FDR = 0.0401; PValue = 0.0119; mean CPM = 13.10; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog" ID="ID_1126064446" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNA13: 1.25-fold Up; FDR = 0.0428; PValue = 0.0128; mean CPM = 15.41; guanine nucleotide binding protein (G protein), alpha 13" ID="ID_526733710" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHRM4: 2.48-fold Down; FDR = 0.0439; PValue = 0.0132; mean CPM = 1.307; cholinergic receptor, muscarinic 4" ID="ID_1609675455" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARPC4: 1.19-fold Down; FDR = 0.0498; PValue = 0.0153; mean CPM = 127.9; actin related protein 2/3 complex, subunit 4, 20kDa" ID="ID_277206388" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APC2: 1.29-fold Down; FDR = 0.0505; PValue = 0.0155; mean CPM = 8.899; adenomatosis polyposis coli 2" ID="ID_1732803348" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NRAS: 1.2-fold Down; FDR = 0.0546; PValue = 0.017; mean CPM = 32.39; neuroblastoma RAS viral (v-ras) oncogene homolog" ID="ID_331819922" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WASF2: 1.18-fold Down; FDR = 0.0671; PValue = 0.0218; mean CPM = 61.92; WAS protein family, member 4" ID="ID_1885764544" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_84386871" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TIAM1: 1.23-fold Up; FDR = 0.0747; PValue = 0.0248; mean CPM = 38.38; T-cell lymphoma invasion and metastasis 1" ID="ID_571468650" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK4: 1.21-fold Down; FDR = 0.0756; PValue = 0.0252; mean CPM = 16.78; p21 protein (Cdc42/Rac)-activated kinase 4" ID="ID_777624016" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB1: 1.23-fold Up; FDR = 0.0759; PValue = 0.0253; mean CPM = 2700; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)" ID="ID_1238839634" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMSB4X: 1.21-fold Down; FDR = 0.0796; PValue = 0.0267; mean CPM = 1843; thymosin-like 2 (pseudogene)" ID="ID_1193312592" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS2: 1.17-fold Up; FDR = 0.1; PValue = 0.0353; mean CPM = 31.79; son of sevenless homolog 2 (Drosophila)" ID="ID_137319202" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIKFYVE: 1.15-fold Up; FDR = 0.119; PValue = 0.0432; mean CPM = 67.91; phosphoinositide kinase, FYVE finger containing" ID="ID_589734058" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC9A1: 1.19-fold Up; FDR = 0.126; PValue = 0.0463; mean CPM = 29.32; solute carrier family 9 (sodium/hydrogen exchanger), member 1" ID="ID_1850954077" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK2: 1.15-fold Up; FDR = 0.134; PValue = 0.0502; mean CPM = 89.49; p21 protein (Cdc42/Rac)-activated kinase 2" ID="ID_1604044170" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGFR1: 1.15-fold Down; FDR = 0.139; PValue = 0.0525; mean CPM = 89.41; fibroblast growth factor receptor 1" ID="ID_110583051" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IQGAP2: 2.02-fold Up; FDR = 0.15; PValue = 0.0577; mean CPM = 1.070; IQ motif containing GTPase activating protein 2" ID="ID_1325389967" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SSH3: 1.14-fold Down; FDR = 0.16; PValue = 0.0621; mean CPM = 43.89; slingshot homolog 3 (Drosophila)" ID="ID_1102529740" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ROCK2: 1.14-fold Up; FDR = 0.166; PValue = 0.065; mean CPM = 247.7; Rho-associated, coiled-coil containing protein kinase 2" ID="ID_763407100" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP1R12A: 1.14-fold Up; FDR = 0.167; PValue = 0.0655; mean CPM = 282.7; protein phosphatase 1, regulatory (inhibitor) subunit 12A" ID="ID_632585844" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RDX: 1.14-fold Up; FDR = 0.168; PValue = 0.066; mean CPM = 58.63; radixin" ID="ID_1310310452" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAIAP2: 1.33-fold Down; FDR = 0.169; PValue = 0.0666; mean CPM = 16.38; BAI1-associated protein 2" ID="ID_1619768476" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BRAF: 1.14-fold Down; FDR = 0.228; PValue = 0.0964; mean CPM = 24.98; v-raf murine sarcoma viral oncogene homolog B1" ID="ID_1869617060" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYFIP1: 1.12-fold Down; FDR = 0.277; PValue = 0.122; mean CPM = 172.0; cytoplasmic FMR1 interacting protein 1" ID="ID_186439855" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYH14: 1.59-fold Down; FDR = 0.304; PValue = 0.138; mean CPM = 1.640; myosin, heavy chain 14, non-muscle" ID="ID_738205644" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARPC1A: 1.11-fold Down; FDR = 0.316; PValue = 0.144; mean CPM = 108.5; actin related protein 2/3 complex, subunit 1A, 41kDa" ID="ID_765561309" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INSRR: 1.92-fold Down; FDR = 0.323; PValue = 0.149; mean CPM = 0.9773; insulin receptor-related receptor" ID="ID_976457699" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_1747154379" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PFN1: 1.12-fold Down; FDR = 0.337; PValue = 0.156; mean CPM = 965.8; profilin 1" ID="ID_1604472300" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APC: 1.1-fold Down; FDR = 0.367; PValue = 0.174; mean CPM = 127.5; adenomatous polyposis coli" ID="ID_1498090281" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRKL: 1.11-fold Up; FDR = 0.371; PValue = 0.176; mean CPM = 34.10; v-crk sarcoma virus CT10 oncogene homolog (avian)-like" ID="ID_1838096108" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1438316943" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2: 1.1-fold Up; FDR = 0.394; PValue = 0.191; mean CPM = 102.5; PTK2 protein tyrosine kinase 2" ID="ID_1036267052" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARPC2: 1.1-fold Up; FDR = 0.401; PValue = 0.195; mean CPM = 335.6; actin related protein 2/3 complex, subunit 2, 34kDa" ID="ID_1152679028" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHRM5: 1.63-fold Up; FDR = 0.411; PValue = 0.201; mean CPM = 1.013; cholinergic receptor, muscarinic 5" ID="ID_1605735653" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RRAS: 1.1-fold Up; FDR = 0.415; PValue = 0.203; mean CPM = 223.0; related RAS viral (r-ras) oncogene homolog" ID="ID_217369091" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_27123409" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="F2R: 1.1-fold Up; FDR = 0.458; PValue = 0.23; mean CPM = 35.05; coagulation factor II (thrombin) receptor" ID="ID_1807750236" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PFN4: 1.47-fold Up; FDR = 0.506; PValue = 0.263; mean CPM = 1.137; profilin family, member 4" ID="ID_692923626" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_1824877825" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYLK2: 1.56-fold Down; FDR = 0.541; PValue = 0.288; mean CPM = 0.9259; myosin light chain kinase 2" ID="ID_430313761" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BDKRB1: 1.18-fold Up; FDR = 0.556; PValue = 0.298; mean CPM = 22.68; bradykinin receptor B1" ID="ID_1483347056" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP1CB: 1.08-fold Up; FDR = 0.566; PValue = 0.306; mean CPM = 108.6; protein phosphatase 1, catalytic subunit, beta isozyme" ID="ID_83539954" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA1: 1.1-fold Down; FDR = 0.57; PValue = 0.308; mean CPM = 422.3; integrin, alpha 1" ID="ID_1944324773" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA9: 1.3-fold Down; FDR = 0.595; PValue = 0.326; mean CPM = 1.685; integrin, alpha 9" ID="ID_134351334" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDC42: 1.07-fold Down; FDR = 0.608; PValue = 0.335; mean CPM = 91.67; cell division cycle 42" ID="ID_643334360" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHRM2: 1.62-fold Down; FDR = 0.635; PValue = 0.356; mean CPM = 0.8398; cholinergic receptor, muscarinic 2" ID="ID_1604266146" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMD4: 1.07-fold Up; FDR = 0.662; PValue = 0.377; mean CPM = 196.2; Macaca mulatta proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 (PSMD4), mRNA." ID="ID_1394599900" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA4: 1.16-fold Down; FDR = 0.722; PValue = 0.425; mean CPM = 5.425; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)" ID="ID_1530174517" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAM: 1.44-fold Down; FDR = 0.73; PValue = 0.432; mean CPM = 0.9052; integrin, alpha M (complement component 3 receptor 3 subunit)" ID="ID_1163176252" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB6: 1.4-fold Down; FDR = 0.732; PValue = 0.434; mean CPM = 0.9377; Integrin beta" ID="ID_982852119" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHRM3: 1.63-fold Up; FDR = 0.761; PValue = 0.46; mean CPM = 0.8102; cholinergic receptor, muscarinic 3" ID="ID_1266784238" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WAS: 1.37-fold Down; FDR = 0.771; PValue = 0.469; mean CPM = 0.9085; Wiskott-Aldrich syndrome" ID="ID_900270328" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRK: 1.05-fold Up; FDR = 0.791; PValue = 0.488; mean CPM = 59.92; v-crk sarcoma virus CT10 oncogene homolog (avian)" ID="ID_120278535" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACTN2: 1.69-fold Down; FDR = 0.791; PValue = 0.488; mean CPM = 0.8357; actinin, alpha 2" ID="ID_1846821941" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYLK4: 1.34-fold Up; FDR = 0.804; PValue = 0.5; mean CPM = 0.8719; Uncharacterized protein" ID="ID_1750413100" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGD3: 1.16-fold Up; FDR = 0.809; PValue = 0.506; mean CPM = 2.084; Uncharacterized protein" ID="ID_1156472205" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DOCK1: 1.05-fold Up; FDR = 0.825; PValue = 0.524; mean CPM = 165.2; dedicator of cytokinesis 1" ID="ID_48039928" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAD: 1.66-fold Down; FDR = 0.85; PValue = 0.56; mean CPM = 0.8625; integrin, alpha D" ID="ID_432873267" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV1: 1.25-fold Down; FDR = 0.858; PValue = 0.572; mean CPM = 0.9515; vav 1 guanine nucleotide exchange factor" ID="ID_1832854294" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1859975887" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYLK3: 1.18-fold Up; FDR = 0.899; PValue = 0.629; mean CPM = 1.107; myosin light chain kinase 3" ID="ID_1568796615" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PFN3: 1.24-fold Down; FDR = 0.899; PValue = 0.631; mean CPM = 0.8001; profilin 3" ID="ID_1215321624" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYL10: 1.36-fold Down; FDR = 0.903; PValue = 0.643; mean CPM = 0.8451; myosin, light chain 10, regulatory" ID="ID_119830190" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PFN3: 1.14-fold Down; FDR = 0.903; PValue = 0.658; mean CPM = 0.7895; Uncharacterized protein" ID="ID_202506866" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYL2: 1.15-fold Up; FDR = 0.909; PValue = 0.69; mean CPM = 0.7911; myosin, light chain 2, regulatory, cardiac, slow" ID="ID_733096577" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LIMK2: 1.14-fold Down; FDR = 0.911; PValue = 0.697; mean CPM = 0.7896; LIM domain kinase 2" ID="ID_398624359" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IQGAP1: 1.03-fold Down; FDR = 0.911; PValue = 0.7; mean CPM = 702.2; IQ motif containing GTPase activating protein 1" ID="ID_1085314288" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK1: 1.03-fold Down; FDR = 0.911; PValue = 0.705; mean CPM = 18.65; p21 protein (Cdc42/Rac)-activated kinase 1" ID="ID_494019482" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARPC5L: 1.03-fold Up; FDR = 0.914; PValue = 0.713; mean CPM = 17.63; actin related protein 2/3 complex, subunit 5-like" ID="ID_1645467032" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHRM1: 1.17-fold Up; FDR = 0.916; PValue = 0.717; mean CPM = 0.9294; cholinergic receptor, muscarinic 1" ID="ID_559584377" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIP5K2B: 1.03-fold Up; FDR = 0.919; PValue = 0.72; mean CPM = 24.71; phosphatidylinositol-5-phosphate 4-kinase, type II, beta" ID="ID_138864583" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYLPF: 1.14-fold Down; FDR = 0.921; PValue = 0.723; mean CPM = 1.015; myosin light chain, phosphorylatable, fast skeletal muscle" ID="ID_737523584" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_950617227" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MOS: 1.02-fold Up; FDR = 0.958; PValue = 0.791; mean CPM = 0.8131; v-mos Moloney murine sarcoma viral oncogene homolog" ID="ID_687755064" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BDKRB2: 1.04-fold Down; FDR = 0.964; PValue = 0.801; mean CPM = 6.559; bradykinin receptor B2" ID="ID_331289464" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_744201492" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFRB: 1.01-fold Up; FDR = 1; PValue = 0.883; mean CPM = 391.1; platelet-derived growth factor receptor, beta polypeptide" ID="ID_1781609955" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK7: 1.01-fold Up; FDR = 1; PValue = 0.923; mean CPM = 0.8495; p21 protein (Cdc42/Rac)-activated kinase 7" ID="ID_766115187" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAL: 1.03-fold Up; FDR = 1; PValue = 0.95; mean CPM = 1.035; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)" ID="ID_838987509" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SCIN: 1.04-fold Up; FDR = 1; PValue = 0.951; mean CPM = 0.8773; scinderin" ID="ID_1101512361" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB7: 1.01-fold Down; FDR = 1; PValue = 0.968; mean CPM = 2.025; integrin, beta 7" ID="ID_1348259994" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV2: No Change; FDR = 1; PValue = 0.976; mean CPM = 25.65; vav 2 guanine nucleotide exchange factor" ID="ID_1525533436" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg RIG-I-like receptor signaling pathway: Activated, FDR = 0.00295, FWER = 0.0443, PValue = 0.000306" ID="ID_657846804" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="IFIH1: 14.7-fold Up; FDR = 8.74e-23; PValue = 1.68e-25; mean CPM = 49.84; interferon induced with helicase C domain 1" ID="ID_1638863508" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DHX58: 3.84-fold Up; FDR = 1.33e-19; PValue = 5.45e-22; mean CPM = 98.66; DEXH (Asp-Glu-X-His) box polypeptide 58" ID="ID_817846738" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRIM25: 3.78-fold Up; FDR = 3.13e-19; PValue = 1.41e-21; mean CPM = 121.6; tripartite motif-containing 25" ID="ID_451721906" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DDX58: 6.4-fold Up; FDR = 5.12e-18; PValue = 3.06e-20; mean CPM = 86.14; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58" ID="ID_740919701" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF7: 14.8-fold Up; FDR = 7.66e-18; PValue = 4.82e-20; mean CPM = 11.54; Macaca mulatta interferon regulatory factor 7 (IRF7), mRNA." ID="ID_334707807" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_1434233534" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ISG15: 15.5-fold Up; FDR = 2.16e-15; PValue = 2.02e-17; mean CPM = 55.60; ISG15 ubiquitin-like modifier" ID="ID_1984763683" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TANK: 1.77-fold Up; FDR = 3.82e-13; PValue = 5.66e-15; mean CPM = 62.24; TRAF family member-associated NFKB activator" ID="ID_507287578" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAVS: 1.92-fold Down; FDR = 2.7e-09; PValue = 1.02e-10; mean CPM = 29.16; mitochondrial antiviral signaling protein" ID="ID_1416041282" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_1456737099" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_901172422" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATG12: 1.67-fold Up; FDR = 8.54e-07; PValue = 6.03e-08; mean CPM = 48.65; ATG12 autophagy related 12 homolog (S. cerevisiae)" ID="ID_704110001" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLRX1: 1.49-fold Down; FDR = 9.67e-07; PValue = 6.97e-08; mean CPM = 54.52; NLR family member X1" ID="ID_801360577" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYLD: 1.46-fold Up; FDR = 1.36e-06; PValue = 1.01e-07; mean CPM = 77.47; cylindromatosis (turban tumor syndrome)" ID="ID_549635451" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_605981040" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBKBP1: 3.3-fold Up; FDR = 6.66e-06; PValue = 5.98e-07; mean CPM = 7.002; TBK1 binding protein 1" ID="ID_769487887" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATG5: 1.37-fold Up; FDR = 0.000194; PValue = 2.63e-05; mean CPM = 36.05; ATG5 autophagy related 5 homolog (S. cerevisiae)" ID="ID_1580978839" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_1600500356" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBK1: 1.3-fold Up; FDR = 0.00337; PValue = 0.000674; mean CPM = 30.46; TANK-binding kinase 1" ID="ID_109939158" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1752964596" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_1350394486" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMEM173: 1.25-fold Up; FDR = 0.00837; PValue = 0.00192; mean CPM = 219.1; transmembrane protein 173" ID="ID_1854542300" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP10: 1.81-fold Up; FDR = 0.0175; PValue = 0.0045; mean CPM = 2.876; caspase 10, apoptosis-related cysteine peptidase" ID="ID_1051403942" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRADD: 1.22-fold Up; FDR = 0.0319; PValue = 0.00907; mean CPM = 34.75; TNFRSF1A-associated via death domain" ID="ID_984611112" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SIKE1: 1.21-fold Up; FDR = 0.0353; PValue = 0.0102; mean CPM = 31.55; suppressor of IKBKE 1" ID="ID_1236736740" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1097975743" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="OTUD5: 1.16-fold Down; FDR = 0.0921; PValue = 0.0318; mean CPM = 54.00; OTU domain containing 5" ID="ID_1001694684" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FADD: 1.18-fold Down; FDR = 0.0936; PValue = 0.0324; mean CPM = 30.89; Uncharacterized protein" ID="ID_1896677598" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_1823284669" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_1945273160" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_1870261663" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1345959254" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK12: 1.19-fold Down; FDR = 0.422; PValue = 0.208; mean CPM = 6.569; mitogen-activated protein kinase 12" ID="ID_24892339" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DDX3X: 1.09-fold Up; FDR = 0.478; PValue = 0.244; mean CPM = 344.2; DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked" ID="ID_1024577839" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK13: 1.22-fold Down; FDR = 0.536; PValue = 0.284; mean CPM = 3.100; mitogen-activated protein kinase 13" ID="ID_4792056" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF3: 1.07-fold Up; FDR = 0.611; PValue = 0.338; mean CPM = 34.56; TNF receptor-associated factor 3" ID="ID_853455160" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIN1: 1.04-fold Down; FDR = 0.845; PValue = 0.554; mean CPM = 85.07; peptidylprolyl cis/trans isomerase, NIMA-interacting 1" ID="ID_1094318321" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RNF125: 1.54-fold Down; FDR = 0.854; PValue = 0.565; mean CPM = 0.8270; ring finger protein 125" ID="ID_1008023637" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1561252324" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKE: 1.03-fold Up; FDR = 0.929; PValue = 0.737; mean CPM = 21.61; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon" ID="ID_1133507123" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_817762050" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DAK: 1.01-fold Up; FDR = 1; PValue = 0.859; mean CPM = 25.02; dihydroxyacetone kinase 2 homolog (S. cerevisiae)" ID="ID_1473013435" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_1330592982" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AZI2: No Change; FDR = 1; PValue = 0.985; mean CPM = 39.18; Uncharacterized protein" ID="ID_182758022" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg HTLV-I infection: Inhibited, FDR = 0.00564, FWER = 0.0941, PValue = 0.000649" ID="ID_519455713" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="ICAM1: 24.6-fold Up; FDR = 2.39e-17; PValue = 1.64e-19; mean CPM = 232.4; intercellular adhesion molecule 1" ID="ID_1570647787" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MRAS: 2.04-fold Up; FDR = 4.47e-15; PValue = 4.43e-17; mean CPM = 41.38; muscle RAS oncogene homolog" ID="ID_692066927" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFRA: 2.76-fold Up; FDR = 3.93e-14; PValue = 4.67e-16; mean CPM = 492.9; platelet-derived growth factor receptor, alpha polypeptide" ID="ID_1281061608" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5A: 2.28-fold Up; FDR = 6.87e-14; PValue = 8.58e-16; mean CPM = 21.55; signal transducer and activator of transcription 5A" ID="ID_608181359" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB3: 4.82-fold Down; FDR = 1.82e-12; PValue = 3.09e-14; mean CPM = 9.911; transforming growth factor, beta 3" ID="ID_1880426617" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC4: 1.85-fold Down; FDR = 1.13e-11; PValue = 2.37e-13; mean CPM = 51.58; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4" ID="ID_351103402" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD2: 2.27-fold Down; FDR = 5e-11; PValue = 1.24e-12; mean CPM = 20.66; frizzled homolog 2 (Drosophila)" ID="ID_1280299217" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SRF: 1.69-fold Down; FDR = 8.07e-11; PValue = 2.06e-12; mean CPM = 34.61; serum response factor (c-fos serum response element-binding transcription factor)" ID="ID_1298316129" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND3: 2.27-fold Down; FDR = 8.38e-11; PValue = 2.15e-12; mean CPM = 86.90; cyclin D3" ID="ID_692332096" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY6: 1.89-fold Down; FDR = 1.9e-10; PValue = 5.38e-12; mean CPM = 141.3; adenylate cyclase 6" ID="ID_1276851191" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALR: 1.71-fold Down; FDR = 1.22e-08; PValue = 5.36e-10; mean CPM = 674.0; calreticulin" ID="ID_521071502" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ANAPC2: 1.55-fold Down; FDR = 1.43e-08; PValue = 6.44e-10; mean CPM = 58.62; anaphase promoting complex subunit 2" ID="ID_1789273576" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1746431684" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RB1: 1.65-fold Up; FDR = 6.01e-08; PValue = 3.2e-09; mean CPM = 59.24; retinoblastoma 1" ID="ID_960453366" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFA: 1.92-fold Down; FDR = 2.56e-07; PValue = 1.58e-08; mean CPM = 22.99; platelet-derived growth factor alpha polypeptide" ID="ID_360792180" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1175578882" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1035819191" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_761808849" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_619063345" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_1269074269" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREM: 2.03-fold Up; FDR = 3.42e-06; PValue = 2.83e-07; mean CPM = 20.56; cAMP responsive element modulator" ID="ID_1937493399" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF1: 1.51-fold Up; FDR = 5.28e-06; PValue = 4.58e-07; mean CPM = 22.13; activating transcription factor 1" ID="ID_152630838" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD7: 1.62-fold Down; FDR = 5.66e-06; PValue = 4.95e-07; mean CPM = 34.19; frizzled homolog 7 (Drosophila)" ID="ID_1759059774" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDC26: 1.48-fold Up; FDR = 9.87e-06; PValue = 9.29e-07; mean CPM = 24.48; cell division cycle 26 homolog (S. cerevisiae)" ID="ID_1237436387" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDC20: 2.65-fold Down; FDR = 1.11e-05; PValue = 1.06e-06; mean CPM = 29.05; cell division cycle 20 homolog (S. cerevisiae)" ID="ID_1719227508" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT5A: 1.65-fold Down; FDR = 2.5e-05; PValue = 2.59e-06; mean CPM = 136.4; wingless-type MMTV integration site family, member 5A" ID="ID_871396592" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1R1: 1.6-fold Up; FDR = 3.35e-05; PValue = 3.61e-06; mean CPM = 123.7; interleukin 1 receptor, type I" ID="ID_757457777" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000009315: 1.44-fold Down; FDR = 4.44e-05; PValue = 4.94e-06; mean CPM = 22.79" ID="ID_296510695" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF3: 1.88-fold Up; FDR = 9.45e-05; PValue = 1.16e-05; mean CPM = 47.95; activating transcription factor 3" ID="ID_396355279" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_1744475681" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACA: 1.36-fold Down; FDR = 0.000167; PValue = 2.22e-05; mean CPM = 37.75; protein kinase, cAMP-dependent, catalytic, alpha" ID="ID_1055889582" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XBP1: 1.34-fold Down; FDR = 0.00023; PValue = 3.19e-05; mean CPM = 127.7; Uncharacterized protein" ID="ID_1614851050" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP3CA: 1.55-fold Up; FDR = 0.0003; PValue = 4.32e-05; mean CPM = 40.21; protein phosphatase 3, catalytic subunit, alpha isozyme" ID="ID_1725624734" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC2: 4.03-fold Down; FDR = 0.000346; PValue = 5.06e-05; mean CPM = 1.347; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2" ID="ID_1667836190" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40: 2.76-fold Up; FDR = 0.00039; PValue = 5.79e-05; mean CPM = 9.139; CD40 molecule, TNF receptor superfamily member 5" ID="ID_1669351101" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF2: 1.34-fold Up; FDR = 0.000403; PValue = 6.01e-05; mean CPM = 39.83; activating transcription factor 2" ID="ID_1071391853" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD9: 2.74-fold Down; FDR = 0.000408; PValue = 6.1e-05; mean CPM = 1.789; frizzled homolog 9 (Drosophila)" ID="ID_969979879" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_751816967" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ELK4: 1.37-fold Up; FDR = 0.000508; PValue = 7.78e-05; mean CPM = 24.59; ELK4, ETS-domain protein (SRF accessory protein 1)" ID="ID_65196190" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD3: 1.38-fold Up; FDR = 0.000573; PValue = 8.94e-05; mean CPM = 114.9; SMAD family member 3" ID="ID_175727169" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT1: 7.1-fold Down; FDR = 0.000659; PValue = 0.000105; mean CPM = 2.664; wingless-type MMTV integration site family, member 1" ID="ID_1206989467" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN2B: 1.63-fold Down; FDR = 0.000936; PValue = 0.000156; mean CPM = 17.34; cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)" ID="ID_1008044275" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDC16: 1.3-fold Up; FDR = 0.00124; PValue = 0.000215; mean CPM = 69.40; cell division cycle 16 homolog (S. cerevisiae)" ID="ID_430619345" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DVL3: 1.29-fold Down; FDR = 0.00157; PValue = 0.00028; mean CPM = 67.95; dishevelled, dsh homolog 3 (Drosophila)" ID="ID_1535381618" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK3: 2.31-fold Up; FDR = 0.00186; PValue = 0.000342; mean CPM = 2.154; Janus kinase 3" ID="ID_1150748542" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD4: 1.83-fold Up; FDR = 0.00258; PValue = 0.000495; mean CPM = 4.537; frizzled homolog 4 (Drosophila)" ID="ID_651386974" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF4: 1.29-fold Up; FDR = 0.00296; PValue = 0.000579; mean CPM = 618.7; activating transcription factor 4 (tax-responsive enhancer element B67)" ID="ID_590206873" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKX: 1.31-fold Down; FDR = 0.00331; PValue = 0.000658; mean CPM = 24.94; protein kinase, X-linked" ID="ID_608390878" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PCNA: 1.34-fold Up; FDR = 0.00398; PValue = 0.000816; mean CPM = 112.1; PCNA antisense RNA (non-protein coding)" ID="ID_628853691" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBPL1: 1.33-fold Up; FDR = 0.00413; PValue = 0.000853; mean CPM = 18.85; TBP-like 1" ID="ID_316592895" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1291140759" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT7A: 3.46-fold Down; FDR = 0.00638; PValue = 0.0014; mean CPM = 1.036; wingless-type MMTV integration site family, member 7A" ID="ID_1428769275" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K14: 1.47-fold Down; FDR = 0.00704; PValue = 0.00157; mean CPM = 9.470; mitogen-activated protein kinase kinase kinase 14" ID="ID_1534553227" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K3: 1.26-fold Down; FDR = 0.00786; PValue = 0.00178; mean CPM = 38.85; mitogen-activated protein kinase kinase kinase 3" ID="ID_500239102" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT10A: 4.08-fold Down; FDR = 0.00805; PValue = 0.00183; mean CPM = 0.9138; wingless-type MMTV integration site family, member 10A" ID="ID_1888412398" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT5B: 1.58-fold Down; FDR = 0.00866; PValue = 0.002; mean CPM = 7.832; wingless-type MMTV integration site family, member 5B" ID="ID_713128356" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY9: 1.32-fold Down; FDR = 0.00986; PValue = 0.00231; mean CPM = 84.04; adenylate cyclase 9" ID="ID_505265373" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLN1: 1.26-fold Down; FDR = 0.0101; PValue = 0.00238; mean CPM = 1820; talin 1" ID="ID_1832289354" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="POLD4: 1.27-fold Down; FDR = 0.0111; PValue = 0.00264; mean CPM = 54.23; polymerase (DNA-directed), delta 4" ID="ID_953430995" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFB: 1.97-fold Down; FDR = 0.0133; PValue = 0.00326; mean CPM = 2.424; platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)" ID="ID_287536643" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT10B: 3.1-fold Down; FDR = 0.0148; PValue = 0.00369; mean CPM = 1.086; wingless-type MMTV integration site family, member 10B" ID="ID_1761339992" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ANAPC10: 1.3-fold Up; FDR = 0.0184; PValue = 0.00478; mean CPM = 14.25; anaphase promoting complex subunit 10" ID="ID_1341401458" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB2: 1.55-fold Down; FDR = 0.0187; PValue = 0.00485; mean CPM = 34.87; Integrin beta" ID="ID_438097409" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHEK2: 1.38-fold Up; FDR = 0.0228; PValue = 0.00613; mean CPM = 20.56; checkpoint kinase 2" ID="ID_1175437395" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_578801293" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRTC1: 1.39-fold Down; FDR = 0.0263; PValue = 0.00721; mean CPM = 6.813; Uncharacterized protein" ID="ID_1932527143" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RRAS2: 1.21-fold Up; FDR = 0.0278; PValue = 0.00771; mean CPM = 61.00; related RAS viral (r-ras) oncogene homolog 2" ID="ID_1029072855" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BUB3: 1.21-fold Up; FDR = 0.0311; PValue = 0.0088; mean CPM = 44.04; budding uninhibited by benzimidazoles 3 homolog (yeast)" ID="ID_1433220970" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB1: 1.21-fold Up; FDR = 0.0313; PValue = 0.00884; mean CPM = 36.07; cAMP responsive element binding protein 1" ID="ID_1703620911" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD2: 1.2-fold Up; FDR = 0.034; PValue = 0.00976; mean CPM = 57.10; SMAD family member 2" ID="ID_234757393" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFBR1: 1.2-fold Up; FDR = 0.037; PValue = 0.0108; mean CPM = 90.92; transforming growth factor, beta receptor 1" ID="ID_1197363478" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1786145530" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KRAS: 1.35-fold Down; FDR = 0.0401; PValue = 0.0119; mean CPM = 13.10; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog" ID="ID_1746261313" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY5: 2.17-fold Down; FDR = 0.042; PValue = 0.0125; mean CPM = 1.219; adenylate cyclase 5" ID="ID_545730238" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="E2F1: 1.44-fold Down; FDR = 0.0425; PValue = 0.0127; mean CPM = 8.857; E2F transcription factor 1" ID="ID_607348840" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY7: 1.24-fold Down; FDR = 0.0434; PValue = 0.013; mean CPM = 157.2; adenylate cyclase 7" ID="ID_399165963" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTNNB1: 1.2-fold Up; FDR = 0.0498; PValue = 0.0153; mean CPM = 558.3; catenin (cadherin-associated protein), beta 1, 88kDa" ID="ID_1601486623" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APC2: 1.29-fold Down; FDR = 0.0505; PValue = 0.0155; mean CPM = 8.899; adenomatosis polyposis coli 2" ID="ID_584049286" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT4: 1.52-fold Down; FDR = 0.0525; PValue = 0.0163; mean CPM = 13.66; wingless-type MMTV integration site family, member 4" ID="ID_1303743276" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NRAS: 1.2-fold Down; FDR = 0.0546; PValue = 0.017; mean CPM = 32.39; neuroblastoma RAS viral (v-ras) oncogene homolog" ID="ID_2281343" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELB: 1.22-fold Down; FDR = 0.0606; PValue = 0.0193; mean CPM = 26.64; v-rel reticuloendotheliosis viral oncogene homolog B" ID="ID_1861878561" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="POLD3: 1.23-fold Up; FDR = 0.0614; PValue = 0.0196; mean CPM = 15.22; polymerase (DNA-directed), delta 3, accessory subunit" ID="ID_692794415" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFBR2: 1.19-fold Up; FDR = 0.0643; PValue = 0.0208; mean CPM = 350.8; transforming growth factor, beta receptor II (70/80kDa)" ID="ID_590521453" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_1459929608" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_1353792947" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_1125637127" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRTC2: 1.18-fold Up; FDR = 0.0976; PValue = 0.0341; mean CPM = 27.36; CREB regulated transcription coactivator 2" ID="ID_1543159022" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ETS1: 1.16-fold Up; FDR = 0.0996; PValue = 0.0348; mean CPM = 94.27; v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)" ID="ID_1502749460" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDC27: 1.16-fold Up; FDR = 0.109; PValue = 0.0389; mean CPM = 116.8; cell division cycle 27 homolog (S. cerevisiae)" ID="ID_1221636286" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_1655852817" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYB: 1.85-fold Down; FDR = 0.12; PValue = 0.0437; mean CPM = 1.320; v-myb myeloblastosis viral oncogene homolog (avian)" ID="ID_1258844462" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND1: 1.17-fold Up; FDR = 0.121; PValue = 0.0443; mean CPM = 867.3; cyclin D1" ID="ID_780158669" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FDPS: 1.15-fold Down; FDR = 0.126; PValue = 0.0464; mean CPM = 49.16; farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)" ID="ID_1346099048" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_513975527" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_117479103" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD1: 1.23-fold Down; FDR = 0.154; PValue = 0.0592; mean CPM = 31.65; frizzled homolog 1 (Drosophila)" ID="ID_860201166" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="POLE3: 1.15-fold Down; FDR = 0.2; PValue = 0.0821; mean CPM = 19.95; polymerase (DNA directed), epsilon 3 (p17 subunit)" ID="ID_1533748862" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT3A: 2.28-fold Down; FDR = 0.2; PValue = 0.0823; mean CPM = 0.8811; wingless-type MMTV integration site family, member 3A" ID="ID_1133572080" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="POLD2: 1.15-fold Down; FDR = 0.21; PValue = 0.0872; mean CPM = 59.57; polymerase (DNA directed), delta 2, regulatory subunit 50kDa" ID="ID_1460800038" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNB2: 1.24-fold Down; FDR = 0.237; PValue = 0.101; mean CPM = 15.12; cyclin B2" ID="ID_790048663" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1A: 1.16-fold Down; FDR = 0.28; PValue = 0.124; mean CPM = 363.2; Cyclin-dependent kinase inhibitor 1; Uncharacterized protein" ID="ID_1242873942" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_1747443948" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1A: 1.11-fold Up; FDR = 0.297; PValue = 0.134; mean CPM = 134.7; tumor necrosis factor receptor superfamily, member 1A" ID="ID_1580436318" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT3: 1.4-fold Up; FDR = 0.304; PValue = 0.138; mean CPM = 1.843; wingless-type MMTV integration site family, member 3" ID="ID_1230602453" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EP300: 1.11-fold Up; FDR = 0.312; PValue = 0.142; mean CPM = 162.8; E1A binding protein p300" ID="ID_1243577881" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ANAPC4: 1.12-fold Up; FDR = 0.321; PValue = 0.147; mean CPM = 30.55; anaphase promoting complex subunit 4" ID="ID_1287961952" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY4: 1.24-fold Up; FDR = 0.328; PValue = 0.151; mean CPM = 8.390; adenylate cyclase 4" ID="ID_1040490859" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_913575475" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND2: 1.2-fold Up; FDR = 0.335; PValue = 0.155; mean CPM = 76.91; cyclin D2" ID="ID_1635200184" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD6: 1.11-fold Down; FDR = 0.347; PValue = 0.162; mean CPM = 39.10; frizzled homolog 6 (Drosophila)" ID="ID_206890614" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP53: 1.11-fold Down; FDR = 0.364; PValue = 0.172; mean CPM = 33.25; tumor protein p53" ID="ID_1691038068" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APC: 1.1-fold Down; FDR = 0.367; PValue = 0.174; mean CPM = 127.5; adenomatous polyposis coli" ID="ID_546137327" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDC23: 1.11-fold Up; FDR = 0.381; PValue = 0.182; mean CPM = 30.67; cell division cycle 23 homolog (S. cerevisiae)" ID="ID_109255427" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1615517266" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD5: 1.34-fold Down; FDR = 0.405; PValue = 0.197; mean CPM = 2.107; frizzled homolog 5 (Drosophila)" ID="ID_1635115907" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBP: 1.12-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 14.69; TATA box binding protein" ID="ID_1231026418" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RRAS: 1.1-fold Up; FDR = 0.415; PValue = 0.203; mean CPM = 223.0; related RAS viral (r-ras) oncogene homolog" ID="ID_227234790" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTTG1: 1.21-fold Down; FDR = 0.43; PValue = 0.212; mean CPM = 25.10; pituitary tumor-transforming 1" ID="ID_1332184862" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC1: 1.11-fold Down; FDR = 0.457; PValue = 0.23; mean CPM = 19.06; Uncharacterized protein" ID="ID_572851643" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT9A: 1.43-fold Down; FDR = 0.505; PValue = 0.262; mean CPM = 2.172; wingless-type MMTV integration site family, member 9A" ID="ID_35114760" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP3CB: 1.08-fold Up; FDR = 0.514; PValue = 0.268; mean CPM = 76.44; protein phosphatase 3, catalytic subunit, beta isozyme" ID="ID_937628745" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_238945080" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT2B: 1.29-fold Down; FDR = 0.621; PValue = 0.345; mean CPM = 1.575; wingless-type MMTV integration site family, member 2B" ID="ID_1670889053" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1R2: 1.37-fold Up; FDR = 0.628; PValue = 0.35; mean CPM = 1.132; interleukin 1 receptor, type II" ID="ID_1720560655" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LTBR: 1.06-fold Down; FDR = 0.683; PValue = 0.394; mean CPM = 91.13; lymphotoxin beta receptor (TNFR superfamily, member 3)" ID="ID_1915195209" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DVL2: 1.06-fold Up; FDR = 0.708; PValue = 0.414; mean CPM = 30.54; dishevelled, dsh homolog 2 (Drosophila)" ID="ID_887593734" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="E2F3: 1.08-fold Up; FDR = 0.751; PValue = 0.452; mean CPM = 11.79; E2F transcription factor 3" ID="ID_1107108912" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC2A1: 1.06-fold Down; FDR = 0.782; PValue = 0.479; mean CPM = 105.3; solute carrier family 2 (facilitated glucose transporter), member 1" ID="ID_497305004" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACG: 1.51-fold Down; FDR = 0.795; PValue = 0.491; mean CPM = 0.8026; protein kinase, cAMP-dependent, catalytic, gamma" ID="ID_1759063195" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBPL2: 1.55-fold Up; FDR = 0.812; PValue = 0.509; mean CPM = 0.7990; TATA box binding protein like 2" ID="ID_1175920261" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT16: 1.27-fold Down; FDR = 0.857; PValue = 0.571; mean CPM = 0.9003; wingless-type MMTV integration site family, member 16" ID="ID_761712678" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1702877600" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY2: 1.18-fold Down; FDR = 0.864; PValue = 0.58; mean CPM = 1.755; adenylate cyclase 2 (brain)" ID="ID_684919159" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_384810812" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY8: 1.28-fold Up; FDR = 0.891; PValue = 0.614; mean CPM = 0.8757; adenylate cyclase 8 (brain)" ID="ID_878357676" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAD2L1: 1.08-fold Up; FDR = 0.898; PValue = 0.624; mean CPM = 10.29; MAD2 mitotic arrest deficient-like 1 (yeast)" ID="ID_1393687436" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK4: 1.04-fold Up; FDR = 0.899; PValue = 0.626; mean CPM = 65.45; cyclin-dependent kinase 4" ID="ID_1332566011" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3D: 1.22-fold Down; FDR = 0.903; PValue = 0.641; mean CPM = 0.7953; CD3d molecule, delta (CD3-TCR complex)" ID="ID_993801229" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT11: 1.18-fold Up; FDR = 0.903; PValue = 0.641; mean CPM = 1.340; wingless-type MMTV integration site family, member 11" ID="ID_171567859" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB2: 1.05-fold Down; FDR = 0.903; PValue = 0.655; mean CPM = 110.8; transforming growth factor, beta 2" ID="ID_167225413" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000021684: 1.44-fold Up; FDR = 0.903; PValue = 0.662; mean CPM = 0.8513; Uncharacterized protein" ID="ID_1716898503" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD4: 1.03-fold Down; FDR = 0.906; PValue = 0.666; mean CPM = 43.02; SMAD family member 4" ID="ID_751099776" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY1: 1.13-fold Down; FDR = 0.908; PValue = 0.682; mean CPM = 1.243; adenylate cyclase 1 (brain)" ID="ID_328547982" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="POLE2: 1.09-fold Down; FDR = 0.908; PValue = 0.682; mean CPM = 3.532; polymerase (DNA directed), epsilon 2 (p59 subunit)" ID="ID_1664437091" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACB: 1.03-fold Up; FDR = 0.911; PValue = 0.694; mean CPM = 30.10; protein kinase, cAMP-dependent, catalytic, beta" ID="ID_660206853" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KAT5: 1.03-fold Down; FDR = 0.916; PValue = 0.715; mean CPM = 42.22; K(lysine) acetyltransferase 5" ID="ID_596026018" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRTC3: 1.03-fold Up; FDR = 0.916; PValue = 0.715; mean CPM = 23.26; CREB regulated transcription coactivator 3" ID="ID_1541887629" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ANAPC11: 1.03-fold Up; FDR = 0.919; PValue = 0.72; mean CPM = 64.64; anaphase promoting complex subunit 11" ID="ID_466901336" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ETS2: 1.04-fold Down; FDR = 0.92; PValue = 0.722; mean CPM = 25.97; v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)" ID="ID_1568804296" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPI1: 1.12-fold Down; FDR = 0.935; PValue = 0.747; mean CPM = 1.030; spleen focus forming virus (SFFV) proviral integration oncogene spi1" ID="ID_1857248142" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB1: 1.02-fold Down; FDR = 0.936; PValue = 0.749; mean CPM = 62.61; transforming growth factor, beta 1" ID="ID_1861964261" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC3: 1.03-fold Down; FDR = 0.952; PValue = 0.78; mean CPM = 13.31; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3" ID="ID_1630065321" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ANAPC5: 1.02-fold Up; FDR = 0.979; PValue = 0.823; mean CPM = 86.90; anaphase promoting complex subunit 5" ID="ID_1332682538" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT8B: 1.21-fold Down; FDR = 0.987; PValue = 0.838; mean CPM = 0.8506; wingless-type MMTV integration site family, member 8B" ID="ID_1427459977" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREBBP: 1.01-fold Down; FDR = 0.993; PValue = 0.847; mean CPM = 137.7; CREB binding protein" ID="ID_421860634" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_712800602" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY3: 1.01-fold Up; FDR = 1; PValue = 0.871; mean CPM = 34.92; adenylate cyclase 3" ID="ID_1905184003" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFRB: 1.01-fold Up; FDR = 1; PValue = 0.883; mean CPM = 391.1; platelet-derived growth factor receptor, beta polypeptide" ID="ID_1375801482" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT2: 1.07-fold Down; FDR = 1; PValue = 0.888; mean CPM = 0.8103; wingless-type MMTV integration site family member 2" ID="ID_1897183848" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DLG1: 1.01-fold Up; FDR = 1; PValue = 0.888; mean CPM = 43.53; discs, large homolog 1 (Drosophila)" ID="ID_272797000" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD3: 1.03-fold Up; FDR = 1; PValue = 0.903; mean CPM = 1.636; frizzled homolog 3 (Drosophila)" ID="ID_120682934" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="E2F2: 1.03-fold Up; FDR = 1; PValue = 0.906; mean CPM = 1.976; E2F transcription factor 2" ID="ID_714501488" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD10: 1.04-fold Down; FDR = 1; PValue = 0.919; mean CPM = 0.8435; frizzled homolog 10 (Drosophila)" ID="ID_802933757" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAL: 1.03-fold Up; FDR = 1; PValue = 0.95; mean CPM = 1.035; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)" ID="ID_315447434" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ANAPC7: No Change; FDR = 1; PValue = 0.954; mean CPM = 48.25; anaphase promoting complex subunit 7" ID="ID_1349441250" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT6: 1.13-fold Down; FDR = 1; PValue = 0.956; mean CPM = 0.8230; wingless-type MMTV integration site family, member 6" ID="ID_731556973" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3G: 1.03-fold Up; FDR = 1; PValue = 0.977; mean CPM = 0.8190; CD3g molecule, gamma (CD3-TCR complex)" ID="ID_1655444696" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3E: 1.07-fold Down; FDR = 1; PValue = 0.981; mean CPM = 0.7994; Uncharacterized protein" ID="ID_650232753" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT9B: 1.03-fold Up; FDR = 1; PValue = 0.991; mean CPM = 0.8041; wingless-type MMTV integration site family, member 9B" ID="ID_1384974105" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg TNF signaling pathway: Activated, FDR = 0.00564, FWER = 0.0992, PValue = 0.000684" ID="ID_855254431" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="MLKL: 8.31-fold Up; FDR = 6.73e-21; PValue = 2.09e-23; mean CPM = 34.78; mixed lineage kinase domain-like" ID="ID_1006632052" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_1963549334" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK3: 3.47-fold Up; FDR = 2.3e-12; PValue = 4.07e-14; mean CPM = 12.05; receptor-interacting serine-threonine kinase 3" ID="ID_1614625564" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3L2: 2.11-fold Down; FDR = 5.05e-12; PValue = 9.78e-14; mean CPM = 64.33; cAMP responsive element binding protein 3-like 2" ID="ID_1040738694" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC2: 1.96-fold Up; FDR = 1.01e-10; PValue = 2.62e-12; mean CPM = 53.58; baculoviral IAP repeat-containing 2" ID="ID_458040110" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CFLAR: 1.87-fold Up; FDR = 5.09e-10; PValue = 1.61e-11; mean CPM = 103.3; CASP8 and FADD-like apoptosis regulator" ID="ID_1558729683" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3L1: 1.99-fold Down; FDR = 1.52e-09; PValue = 5.36e-11; mean CPM = 211.4; cAMP responsive element binding protein 3-like 1" ID="ID_1061920441" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_281496480" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_890264359" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_1672658033" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1936648132" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1905663672" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_145538183" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC3: 2.79-fold Up; FDR = 1.74e-06; PValue = 1.32e-07; mean CPM = 95.34; baculoviral IAP repeat-containing 3" ID="ID_621932583" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1900920390" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1B: 2.24-fold Up; FDR = 2.68e-06; PValue = 2.16e-07; mean CPM = 19.44; tumor necrosis factor receptor superfamily, member 1B" ID="ID_1839519604" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K3: 1.45-fold Down; FDR = 7.01e-06; PValue = 6.34e-07; mean CPM = 180.1; mitogen-activated protein kinase kinase 3" ID="ID_277837387" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA5: 3.28-fold Up; FDR = 1.4e-05; PValue = 1.36e-06; mean CPM = 2.288; ribosomal protein S6 kinase, 90kDa, polypeptide 5" ID="ID_1537669306" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_220115004" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB5: 2.1-fold Down; FDR = 0.000248; PValue = 3.48e-05; mean CPM = 4.269; cAMP responsive element binding protein 5" ID="ID_1180871817" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF2: 1.34-fold Up; FDR = 0.000403; PValue = 6.01e-05; mean CPM = 39.83; activating transcription factor 2" ID="ID_480902725" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAG4: 1.32-fold Up; FDR = 0.00191; PValue = 0.000353; mean CPM = 25.62; BCL2-associated athanogene 4" ID="ID_1975708020" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF4: 1.29-fold Up; FDR = 0.00296; PValue = 0.000579; mean CPM = 618.7; activating transcription factor 4 (tax-responsive enhancer element B67)" ID="ID_1404996571" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_299644799" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_1001935874" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K14: 1.47-fold Down; FDR = 0.00704; PValue = 0.00157; mean CPM = 9.470; mitogen-activated protein kinase kinase kinase 14" ID="ID_1774580764" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP10: 1.81-fold Up; FDR = 0.0175; PValue = 0.0045; mean CPM = 2.876; caspase 10, apoptosis-related cysteine peptidase" ID="ID_1688102697" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PXMP2: 1.24-fold Down; FDR = 0.019; PValue = 0.00496; mean CPM = 27.63; phosphoglycerate mutase family member 5" ID="ID_1013987867" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1619331750" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DNM1L: 1.21-fold Up; FDR = 0.0244; PValue = 0.00662; mean CPM = 91.13; dynamin 1-like" ID="ID_1431775229" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1549881121" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB1: 1.21-fold Up; FDR = 0.0313; PValue = 0.00884; mean CPM = 36.07; cAMP responsive element binding protein 1" ID="ID_483983391" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRADD: 1.22-fold Up; FDR = 0.0319; PValue = 0.00907; mean CPM = 34.75; TNFRSF1A-associated via death domain" ID="ID_481268626" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1873282185" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K8: 1.35-fold Down; FDR = 0.0831; PValue = 0.0281; mean CPM = 8.912; mitogen-activated protein kinase kinase kinase 8" ID="ID_1059020318" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FADD: 1.18-fold Down; FDR = 0.0936; PValue = 0.0324; mean CPM = 30.89; Uncharacterized protein" ID="ID_1472025097" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3L4: 1.3-fold Down; FDR = 0.0961; PValue = 0.0334; mean CPM = 6.034; cAMP responsive element binding protein 3-like 4" ID="ID_771468153" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_138934474" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3: 1.15-fold Up; FDR = 0.128; PValue = 0.0472; mean CPM = 167.9; cAMP responsive element binding protein 3" ID="ID_1618618274" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_531049342" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1372767734" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP7: 1.15-fold Up; FDR = 0.218; PValue = 0.0916; mean CPM = 21.49; caspase 7, apoptosis-related cysteine peptidase" ID="ID_1233025498" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_293892459" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA4: 1.12-fold Down; FDR = 0.296; PValue = 0.133; mean CPM = 39.50; ribosomal protein S6 kinase, 90kDa, polypeptide 4" ID="ID_1559777329" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1A: 1.11-fold Up; FDR = 0.297; PValue = 0.134; mean CPM = 134.7; tumor necrosis factor receptor superfamily, member 1A" ID="ID_561589163" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_1936102230" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_471082672" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_997210613" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_362506659" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK12: 1.19-fold Down; FDR = 0.422; PValue = 0.208; mean CPM = 6.569; mitogen-activated protein kinase 12" ID="ID_486011658" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1050206289" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_819849567" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK13: 1.22-fold Down; FDR = 0.536; PValue = 0.284; mean CPM = 3.100; mitogen-activated protein kinase 13" ID="ID_1278960127" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K5: 1.21-fold Down; FDR = 0.6; PValue = 0.33; mean CPM = 8.023; mitogen-activated protein kinase kinase kinase 5" ID="ID_1827599962" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_576972505" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREBL1: 1.05-fold Down; FDR = 0.794; PValue = 0.491; mean CPM = 64.18; activating transcription factor 6 beta" ID="ID_348699641" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_588852525" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_845552254" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAGI2: 1.06-fold Down; FDR = 0.903; PValue = 0.655; mean CPM = 7.972; Uncharacterized protein" ID="ID_930724791" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3L3: 1.4-fold Down; FDR = 0.908; PValue = 0.679; mean CPM = 0.8407; cAMP responsive element binding protein 3-like 3" ID="ID_1201517405" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_1095500560" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_1038835857" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Measles: Activated, FDR = 0.00564, FWER = 0.101, PValue = 0.0007" ID="ID_1225673551" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TLR2: 8.94-fold Up; FDR = 6.97e-23; PValue = 1.25e-25; mean CPM = 18.41; toll-like receptor 2" ID="ID_1340589509" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFIH1: 14.7-fold Up; FDR = 8.74e-23; PValue = 1.68e-25; mean CPM = 49.84; interferon induced with helicase C domain 1" ID="ID_1719205575" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF9: 3.85-fold Up; FDR = 2.6e-19; PValue = 1.12e-21; mean CPM = 106.4; interferon regulatory factor 9" ID="ID_837333104" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT2: 2.67-fold Up; FDR = 8.02e-19; PValue = 4.03e-21; mean CPM = 185.6; signal transducer and activator of transcription 2, 113kDa" ID="ID_781012463" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_1656066600" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_996776633" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DDX58: 6.4-fold Up; FDR = 5.12e-18; PValue = 3.06e-20; mean CPM = 86.14; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58" ID="ID_1467037289" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2AK2: 3.01-fold Up; FDR = 6.08e-18; PValue = 3.74e-20; mean CPM = 47.85; eukaryotic translation initiation factor 2-alpha kinase 2" ID="ID_983644090" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF7: 14.8-fold Up; FDR = 7.66e-18; PValue = 4.82e-20; mean CPM = 11.54; Macaca mulatta interferon regulatory factor 7 (IRF7), mRNA." ID="ID_654078712" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF10: 44.5-fold Up; FDR = 2.83e-16; PValue = 2.4e-18; mean CPM = 6.029; Tumor necrosis factor ligand superfamily member 10 isoform 1; Uncharacterized protein" ID="ID_36933128" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5A: 2.28-fold Up; FDR = 6.87e-14; PValue = 8.58e-16; mean CPM = 21.55; signal transducer and activator of transcription 5A" ID="ID_503248664" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_143721279" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND3: 2.27-fold Down; FDR = 8.38e-11; PValue = 2.15e-12; mean CPM = 86.90; cyclin D3" ID="ID_347239676" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAVS: 1.92-fold Down; FDR = 2.7e-09; PValue = 1.02e-10; mean CPM = 29.16; mitochondrial antiviral signaling protein" ID="ID_1794614800" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR4: 3.45-fold Up; FDR = 3.1e-09; PValue = 1.19e-10; mean CPM = 7.456; Macaca mulatta toll-like receptor 4 (TLR4), mRNA." ID="ID_702202591" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1B: 1.64-fold Up; FDR = 1.22e-08; PValue = 5.39e-10; mean CPM = 32.96; Cyclin-dependent kinase inhibitor 1B; Uncharacterized protein" ID="ID_230771319" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RCHY1: 2.04-fold Up; FDR = 1.35e-08; PValue = 6.04e-10; mean CPM = 25.49; ring finger and CHY zinc finger domain containing 1" ID="ID_1967961863" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK4: 1.8-fold Up; FDR = 3.31e-08; PValue = 1.64e-09; mean CPM = 12.89; interleukin-1 receptor-associated kinase 4" ID="ID_482706439" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_188493910" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_376020206" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_299256015" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_1566311212" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR2: 1.74-fold Up; FDR = 1.85e-06; PValue = 1.44e-07; mean CPM = 26.05; interferon (alpha, beta and omega) receptor 2" ID="ID_1224800292" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2AK3: 1.59-fold Down; FDR = 2.47e-06; PValue = 1.96e-07; mean CPM = 33.81; eukaryotic translation initiation factor 2-alpha kinase 3" ID="ID_302543269" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_1525560195" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFAIP3: 1.79-fold Up; FDR = 3.14e-05; PValue = 3.34e-06; mean CPM = 52.47; tumor necrosis factor, alpha-induced protein 3" ID="ID_1390377547" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2S1: 1.42-fold Up; FDR = 5.59e-05; PValue = 6.42e-06; mean CPM = 79.87; eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa" ID="ID_1126162421" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF10D: 1.84-fold Down; FDR = 5.9e-05; PValue = 6.84e-06; mean CPM = 32.06; tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain" ID="ID_210146967" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP2: 1.45-fold Up; FDR = 0.000179; PValue = 2.4e-05; mean CPM = 65.31; TGF-beta activated kinase 1/MAP3K7 binding protein 2" ID="ID_463022429" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR1: 1.31-fold Up; FDR = 0.00151; PValue = 0.000268; mean CPM = 37.77; interferon gamma receptor 1" ID="ID_429678145" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK3: 2.31-fold Up; FDR = 0.00186; PValue = 0.000342; mean CPM = 2.154; Janus kinase 3" ID="ID_1922536283" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBK1: 1.3-fold Up; FDR = 0.00337; PValue = 0.000674; mean CPM = 30.46; TANK-binding kinase 1" ID="ID_1429200531" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1493801827" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12A: 2.09-fold Up; FDR = 0.00924; PValue = 0.00215; mean CPM = 2.872; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)" ID="ID_1057681507" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR1: 1.27-fold Up; FDR = 0.0101; PValue = 0.00237; mean CPM = 82.39; Uncharacterized protein" ID="ID_132275840" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYK2: 1.24-fold Down; FDR = 0.0142; PValue = 0.00354; mean CPM = 42.58; tyrosine kinase 2" ID="ID_841554234" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FYN: 1.22-fold Up; FDR = 0.0156; PValue = 0.00393; mean CPM = 92.94; FYN oncogene related to SRC, FGR, YES" ID="ID_656938429" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FCGR2B: 2.01-fold Up; FDR = 0.0231; PValue = 0.00623; mean CPM = 1.743; Uncharacterized protein" ID="ID_420702301" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1198988753" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR2: 1.23-fold Up; FDR = 0.0258; PValue = 0.00707; mean CPM = 46.52; interferon gamma receptor 2 (interferon gamma transducer 1)" ID="ID_1454281107" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_951257444" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_125668756" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND1: 1.17-fold Up; FDR = 0.121; PValue = 0.0443; mean CPM = 867.3; cyclin D1" ID="ID_208902331" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_43502396" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNE1: 1.2-fold Up; FDR = 0.278; PValue = 0.123; mean CPM = 6.609; cyclin E1" ID="ID_1818838632" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_555566251" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_999263750" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND2: 1.2-fold Up; FDR = 0.335; PValue = 0.155; mean CPM = 76.91; cyclin D2" ID="ID_1071947963" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF10B: 1.13-fold Down; FDR = 0.343; PValue = 0.16; mean CPM = 40.59; tumor necrosis factor receptor superfamily, member 10b" ID="ID_1526042845" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP53: 1.11-fold Down; FDR = 0.364; PValue = 0.172; mean CPM = 33.25; tumor protein p53" ID="ID_206433226" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_729068786" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DOK1: 1.12-fold Down; FDR = 0.406; PValue = 0.198; mean CPM = 92.16; docking protein 1, 62kDa (downstream of tyrosine kinase 1)" ID="ID_235821667" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2AK1: 1.09-fold Up; FDR = 0.499; PValue = 0.258; mean CPM = 34.88; Uncharacterized protein" ID="ID_1627962136" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCQ: 1.56-fold Up; FDR = 0.522; PValue = 0.274; mean CPM = 1.047; Uncharacterized protein" ID="ID_1508329905" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_41988401" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2AK4: 1.06-fold Up; FDR = 0.681; PValue = 0.391; mean CPM = 104.8; eukaryotic translation initiation factor 2 alpha kinase 4" ID="ID_906000139" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNB1: 1.79-fold Up; FDR = 0.731; PValue = 0.433; mean CPM = 0.8526; interferon, beta 1, fibroblast" ID="ID_1513139557" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF10A: 1.06-fold Down; FDR = 0.732; PValue = 0.434; mean CPM = 42.75; tumor necrosis factor receptor superfamily, member 10a" ID="ID_1336073854" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA6: 1.41-fold Down; FDR = 0.807; PValue = 0.504; mean CPM = 0.8019; interferon, alpha 6" ID="ID_852119186" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1850814440" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CBLB: 1.04-fold Down; FDR = 0.859; PValue = 0.574; mean CPM = 64.59; Cas-Br-M (murine) ecotropic retroviral transforming sequence b" ID="ID_1842581999" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR7: 1.37-fold Down; FDR = 0.878; PValue = 0.597; mean CPM = 0.8402; toll-like receptor 7" ID="ID_519900843" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK1: 1.04-fold Down; FDR = 0.885; PValue = 0.606; mean CPM = 41.54; interleukin-1 receptor-associated kinase 1" ID="ID_1692008713" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_181102934" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3D: 1.22-fold Down; FDR = 0.903; PValue = 0.641; mean CPM = 0.7953; CD3d molecule, delta (CD3-TCR complex)" ID="ID_369082000" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA13: 1.13-fold Up; FDR = 0.908; PValue = 0.677; mean CPM = 0.7960; interferon, alpha 13" ID="ID_1605139600" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA8: 1.13-fold Down; FDR = 0.911; PValue = 0.702; mean CPM = 0.7910; interferon, alpha 8" ID="ID_606329674" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKE: 1.03-fold Up; FDR = 0.929; PValue = 0.737; mean CPM = 21.61; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon" ID="ID_1782361856" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FASLG: 1.2-fold Down; FDR = 0.941; PValue = 0.757; mean CPM = 0.8088; Fas ligand (TNF superfamily, member 6)" ID="ID_1734236802" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2RA: 1.08-fold Up; FDR = 0.945; PValue = 0.766; mean CPM = 0.8493; interleukin 2 receptor, alpha" ID="ID_428705620" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNE2: 1.05-fold Up; FDR = 0.962; PValue = 0.796; mean CPM = 6.415; cyclin E2" ID="ID_805353021" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA14: 1.22-fold Up; FDR = 0.965; PValue = 0.802; mean CPM = 0.8654; interferon, alpha 14" ID="ID_1608372638" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_1598668019" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA4: 1.28-fold Down; FDR = 0.983; PValue = 0.829; mean CPM = 0.8584; interferon, alpha 4" ID="ID_1607401349" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12B: 1.07-fold Up; FDR = 0.983; PValue = 0.831; mean CPM = 0.8197; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)" ID="ID_442971841" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLAMF1: 1.1-fold Down; FDR = 0.996; PValue = 0.852; mean CPM = 0.8320; signaling lymphocytic activation molecule family member 1" ID="ID_684349780" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR9: 1.01-fold Down; FDR = 1; PValue = 0.859; mean CPM = 21.45; Macaca mulatta toll-like receptor 9 (TLR9), mRNA." ID="ID_1337810526" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_1867395918" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3G: 1.03-fold Up; FDR = 1; PValue = 0.977; mean CPM = 0.8190; CD3g molecule, gamma (CD3-TCR complex)" ID="ID_1600430892" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3E: 1.07-fold Down; FDR = 1; PValue = 0.981; mean CPM = 0.7994; Uncharacterized protein" ID="ID_1448932018" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2: 1.03-fold Up; FDR = 1; PValue = 0.998; mean CPM = 0.7974; interleukin 2" ID="ID_36601088" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA1: No Change; FDR = 1; PValue = 0.998; mean CPM = 0.8014; interferon, alpha 1" ID="ID_1497179316" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SH2D1A: No Change; FDR = 1; PValue = 1; mean CPM = 0.7843; SH2 domain containing 1A" ID="ID_1092753312" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Melanogenesis: Inhibited, FDR = 0.0105, FWER = 0.2, PValue = 0.00138" ID="ID_769071308" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CREB3L2: 2.11-fold Down; FDR = 5.05e-12; PValue = 9.78e-14; mean CPM = 64.33; cAMP responsive element binding protein 3-like 2" ID="ID_75475028" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD2: 2.27-fold Down; FDR = 5e-11; PValue = 1.24e-12; mean CPM = 20.66; frizzled homolog 2 (Drosophila)" ID="ID_1119231310" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY6: 1.89-fold Down; FDR = 1.9e-10; PValue = 5.38e-12; mean CPM = 141.3; adenylate cyclase 6" ID="ID_441712524" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3L1: 1.99-fold Down; FDR = 1.52e-09; PValue = 5.36e-11; mean CPM = 211.4; cAMP responsive element binding protein 3-like 1" ID="ID_1483639013" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAMK2D: 1.54-fold Up; FDR = 4.06e-08; PValue = 2.07e-09; mean CPM = 51.52; calcium/calmodulin-dependent protein kinase II delta" ID="ID_1337854185" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TUBB3: 2.3-fold Down; FDR = 7.99e-08; PValue = 4.36e-09; mean CPM = 16.43; melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)" ID="ID_1774987520" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCB1: 1.71-fold Up; FDR = 1.31e-06; PValue = 9.73e-08; mean CPM = 34.36; phospholipase C, beta 1 (phosphoinositide-specific)" ID="ID_1915640032" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD7: 1.62-fold Down; FDR = 5.66e-06; PValue = 4.95e-07; mean CPM = 34.19; frizzled homolog 7 (Drosophila)" ID="ID_940827645" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1408166277" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT5A: 1.65-fold Down; FDR = 2.5e-05; PValue = 2.59e-06; mean CPM = 136.4; wingless-type MMTV integration site family, member 5A" ID="ID_1016792445" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000009315: 1.44-fold Down; FDR = 4.44e-05; PValue = 4.94e-06; mean CPM = 22.79" ID="ID_801982207" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAI1: 1.47-fold Up; FDR = 5.94e-05; PValue = 6.9e-06; mean CPM = 97.19; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1" ID="ID_303475671" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACA: 1.36-fold Down; FDR = 0.000167; PValue = 2.22e-05; mean CPM = 37.75; protein kinase, cAMP-dependent, catalytic, alpha" ID="ID_1718710374" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCB4: 1.75-fold Down; FDR = 0.00025; PValue = 3.52e-05; mean CPM = 6.730; phospholipase C, beta 4" ID="ID_707546972" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD9: 2.74-fold Down; FDR = 0.000408; PValue = 6.1e-05; mean CPM = 1.789; frizzled homolog 9 (Drosophila)" ID="ID_306619091" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT1: 7.1-fold Down; FDR = 0.000659; PValue = 0.000105; mean CPM = 2.664; wingless-type MMTV integration site family, member 1" ID="ID_1655162534" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALM3: 1.41-fold Down; FDR = 0.000714; PValue = 0.000115; mean CPM = 94.24; calmodulin 3 (phosphorylase kinase, delta)" ID="ID_1603496611" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAMK2A: 2.29-fold Down; FDR = 0.00124; PValue = 0.000217; mean CPM = 2.001; calcium/calmodulin-dependent protein kinase II alpha" ID="ID_1675896534" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DVL3: 1.29-fold Down; FDR = 0.00157; PValue = 0.00028; mean CPM = 67.95; dishevelled, dsh homolog 3 (Drosophila)" ID="ID_1331902970" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAS1: 1.31-fold Down; FDR = 0.00158; PValue = 0.000283; mean CPM = 564.9; Uncharacterized protein" ID="ID_1271147442" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD4: 1.83-fold Up; FDR = 0.00258; PValue = 0.000495; mean CPM = 4.537; frizzled homolog 4 (Drosophila)" ID="ID_1288775194" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKX: 1.31-fold Down; FDR = 0.00331; PValue = 0.000658; mean CPM = 24.94; protein kinase, X-linked" ID="ID_1995935517" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAI3: 1.26-fold Up; FDR = 0.00487; PValue = 0.00103; mean CPM = 113.8; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3" ID="ID_75839597" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAMK2B: 3.82-fold Down; FDR = 0.00536; PValue = 0.00115; mean CPM = 1.542; calcium/calmodulin-dependent protein kinase II beta" ID="ID_1765712642" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT7A: 3.46-fold Down; FDR = 0.00638; PValue = 0.0014; mean CPM = 1.036; wingless-type MMTV integration site family, member 7A" ID="ID_937370445" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT10A: 4.08-fold Down; FDR = 0.00805; PValue = 0.00183; mean CPM = 0.9138; wingless-type MMTV integration site family, member 10A" ID="ID_658443618" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT5B: 1.58-fold Down; FDR = 0.00866; PValue = 0.002; mean CPM = 7.832; wingless-type MMTV integration site family, member 5B" ID="ID_1627158446" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY9: 1.32-fold Down; FDR = 0.00986; PValue = 0.00231; mean CPM = 84.04; adenylate cyclase 9" ID="ID_607381960" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT10B: 3.1-fold Down; FDR = 0.0148; PValue = 0.00369; mean CPM = 1.086; wingless-type MMTV integration site family, member 10B" ID="ID_1814681633" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_882491639" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB1: 1.21-fold Up; FDR = 0.0313; PValue = 0.00884; mean CPM = 36.07; cAMP responsive element binding protein 1" ID="ID_1890578470" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TCF7: 1.72-fold Down; FDR = 0.0376; PValue = 0.011; mean CPM = 4.279; transcription factor 7 (T-cell specific, HMG-box)" ID="ID_730966744" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KRAS: 1.35-fold Down; FDR = 0.0401; PValue = 0.0119; mean CPM = 13.10; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog" ID="ID_1270597327" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY5: 2.17-fold Down; FDR = 0.042; PValue = 0.0125; mean CPM = 1.219; adenylate cyclase 5" ID="ID_18471175" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY7: 1.24-fold Down; FDR = 0.0434; PValue = 0.013; mean CPM = 157.2; adenylate cyclase 7" ID="ID_1536419497" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCB2: 3.68-fold Down; FDR = 0.0481; PValue = 0.0147; mean CPM = 1.557; Uncharacterized protein" ID="ID_412771894" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTNNB1: 1.2-fold Up; FDR = 0.0498; PValue = 0.0153; mean CPM = 558.3; catenin (cadherin-associated protein), beta 1, 88kDa" ID="ID_1105118570" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT4: 1.52-fold Down; FDR = 0.0525; PValue = 0.0163; mean CPM = 13.66; wingless-type MMTV integration site family, member 4" ID="ID_1706155788" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NRAS: 1.2-fold Down; FDR = 0.0546; PValue = 0.017; mean CPM = 32.39; neuroblastoma RAS viral (v-ras) oncogene homolog" ID="ID_126334331" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_1214349257" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TCF7L1: 1.2-fold Down; FDR = 0.0783; PValue = 0.0262; mean CPM = 25.11; transcription factor 7-like 1 (T-cell specific, HMG-box)" ID="ID_637067468" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3L4: 1.3-fold Down; FDR = 0.0961; PValue = 0.0334; mean CPM = 6.034; cAMP responsive element binding protein 3-like 4" ID="ID_1788243590" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALM1: 1.18-fold Down; FDR = 0.104; PValue = 0.0368; mean CPM = 292.9; calmodulin 1 (phosphorylase kinase, delta)" ID="ID_1369229716" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3: 1.15-fold Up; FDR = 0.128; PValue = 0.0472; mean CPM = 167.9; cAMP responsive element binding protein 3" ID="ID_1986709558" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAI2: 1.15-fold Down; FDR = 0.134; PValue = 0.0501; mean CPM = 356.3; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2" ID="ID_897694607" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_603739140" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD1: 1.23-fold Down; FDR = 0.154; PValue = 0.0592; mean CPM = 31.65; frizzled homolog 1 (Drosophila)" ID="ID_1350407077" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT3A: 2.28-fold Down; FDR = 0.2; PValue = 0.0823; mean CPM = 0.8811; wingless-type MMTV integration site family, member 3A" ID="ID_462650841" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KITLG: 1.31-fold Up; FDR = 0.209; PValue = 0.0867; mean CPM = 5.766; KIT ligand" ID="ID_1174746900" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT3: 1.4-fold Up; FDR = 0.304; PValue = 0.138; mean CPM = 1.843; wingless-type MMTV integration site family, member 3" ID="ID_1148157342" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EP300: 1.11-fold Up; FDR = 0.312; PValue = 0.142; mean CPM = 162.8; E1A binding protein p300" ID="ID_1388448588" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY4: 1.24-fold Up; FDR = 0.328; PValue = 0.151; mean CPM = 8.390; adenylate cyclase 4" ID="ID_763426391" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALM1: 1.11-fold Up; FDR = 0.343; PValue = 0.16; mean CPM = 412.7; Calmodulin; Uncharacterized protein" ID="ID_63751381" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD6: 1.11-fold Down; FDR = 0.347; PValue = 0.162; mean CPM = 39.10; frizzled homolog 6 (Drosophila)" ID="ID_1448033715" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DCT: 1.48-fold Down; FDR = 0.397; PValue = 0.192; mean CPM = 1.362; dopachrome tautomerase" ID="ID_1171121564" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD5: 1.34-fold Down; FDR = 0.405; PValue = 0.197; mean CPM = 2.107; frizzled homolog 5 (Drosophila)" ID="ID_140720854" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1010129228" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT9A: 1.43-fold Down; FDR = 0.505; PValue = 0.262; mean CPM = 2.172; wingless-type MMTV integration site family, member 9A" ID="ID_1031136341" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCG: 1.47-fold Down; FDR = 0.609; PValue = 0.336; mean CPM = 0.9297; protein kinase C, gamma" ID="ID_1918556780" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT2B: 1.29-fold Down; FDR = 0.621; PValue = 0.345; mean CPM = 1.575; wingless-type MMTV integration site family, member 2B" ID="ID_1187265850" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EDNRB: 1.35-fold Up; FDR = 0.649; PValue = 0.367; mean CPM = 1.276; endothelin receptor type B" ID="ID_1073269653" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LEF1: 1.2-fold Up; FDR = 0.691; PValue = 0.4; mean CPM = 2.488; lymphoid enhancer-binding factor 1" ID="ID_1195664865" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DVL2: 1.06-fold Up; FDR = 0.708; PValue = 0.414; mean CPM = 30.54; dishevelled, dsh homolog 2 (Drosophila)" ID="ID_1767615144" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCB: 1.86-fold Up; FDR = 0.727; PValue = 0.43; mean CPM = 0.8705; protein kinase C, beta" ID="ID_1439133426" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACG: 1.51-fold Down; FDR = 0.795; PValue = 0.491; mean CPM = 0.8026; protein kinase, cAMP-dependent, catalytic, gamma" ID="ID_1489488215" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALML5: 1.49-fold Up; FDR = 0.819; PValue = 0.518; mean CPM = 0.8129; calmodulin-like 5" ID="ID_807715639" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT16: 1.27-fold Down; FDR = 0.857; PValue = 0.571; mean CPM = 0.9003; wingless-type MMTV integration site family, member 16" ID="ID_157100320" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYR: 1.26-fold Up; FDR = 0.861; PValue = 0.577; mean CPM = 0.7997; tyrosinase (oculocutaneous albinism IA)" ID="ID_1156103056" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY2: 1.18-fold Down; FDR = 0.864; PValue = 0.58; mean CPM = 1.755; adenylate cyclase 2 (brain)" ID="ID_470461836" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_564466319" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALML6: 1.1-fold Up; FDR = 0.888; PValue = 0.61; mean CPM = 6.655; calmodulin-like 6" ID="ID_261758735" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAQ: 1.05-fold Down; FDR = 0.889; PValue = 0.611; mean CPM = 9.623; Guanine nucleotide-binding protein G(Q) subunit alpha; Uncharacterized protein" ID="ID_1595026490" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY8: 1.28-fold Up; FDR = 0.891; PValue = 0.614; mean CPM = 0.8757; adenylate cyclase 8 (brain)" ID="ID_1426069904" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT11: 1.18-fold Up; FDR = 0.903; PValue = 0.641; mean CPM = 1.340; wingless-type MMTV integration site family, member 11" ID="ID_1395401527" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000021684: 1.44-fold Up; FDR = 0.903; PValue = 0.662; mean CPM = 0.8513; Uncharacterized protein" ID="ID_396417466" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3L3: 1.4-fold Down; FDR = 0.908; PValue = 0.679; mean CPM = 0.8407; cAMP responsive element binding protein 3-like 3" ID="ID_636236496" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY1: 1.13-fold Down; FDR = 0.908; PValue = 0.682; mean CPM = 1.243; adenylate cyclase 1 (brain)" ID="ID_787431551" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACB: 1.03-fold Up; FDR = 0.911; PValue = 0.694; mean CPM = 30.10; protein kinase, cAMP-dependent, catalytic, beta" ID="ID_1637124250" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALML3: 1.41-fold Down; FDR = 0.911; PValue = 0.698; mean CPM = 0.8159; calmodulin-like 3" ID="ID_379956657" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EDN1: 1.04-fold Up; FDR = 0.935; PValue = 0.748; mean CPM = 36.20; endothelin 1" ID="ID_1666568465" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_1599723558" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016883: 1.11-fold Down; FDR = 0.97; PValue = 0.811; mean CPM = 0.8838; Uncharacterized protein" ID="ID_845364946" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT8B: 1.21-fold Down; FDR = 0.987; PValue = 0.838; mean CPM = 0.8506; wingless-type MMTV integration site family, member 8B" ID="ID_58442988" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREBBP: 1.01-fold Down; FDR = 0.993; PValue = 0.847; mean CPM = 137.7; CREB binding protein" ID="ID_838600538" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="POMC: 1.04-fold Down; FDR = 1; PValue = 0.862; mean CPM = 0.8249; proopiomelanocortin" ID="ID_1757842708" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAO1: 1.1-fold Down; FDR = 1; PValue = 0.866; mean CPM = 0.8448; guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O" ID="ID_1745165838" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY3: 1.01-fold Up; FDR = 1; PValue = 0.871; mean CPM = 34.92; adenylate cyclase 3" ID="ID_1264149711" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT2: 1.07-fold Down; FDR = 1; PValue = 0.888; mean CPM = 0.8103; wingless-type MMTV integration site family member 2" ID="ID_1881870720" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ASIP: 1.04-fold Up; FDR = 1; PValue = 0.9; mean CPM = 0.8988; agouti signaling protein, nonagouti homolog (mouse)" ID="ID_697340299" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD3: 1.03-fold Up; FDR = 1; PValue = 0.903; mean CPM = 1.636; frizzled homolog 3 (Drosophila)" ID="ID_1889581225" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD10: 1.04-fold Down; FDR = 1; PValue = 0.919; mean CPM = 0.8435; frizzled homolog 10 (Drosophila)" ID="ID_1235064301" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYRP1: 1.12-fold Up; FDR = 1; PValue = 0.931; mean CPM = 0.8375; tyrosinase-related protein 1" ID="ID_842944588" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT6: 1.13-fold Down; FDR = 1; PValue = 0.956; mean CPM = 0.8230; wingless-type MMTV integration site family, member 6" ID="ID_836167827" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAQ: No Change; FDR = 1; PValue = 0.975; mean CPM = 15.20; guanine nucleotide binding protein (G protein), q polypeptide" ID="ID_1124101224" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT9B: 1.03-fold Up; FDR = 1; PValue = 0.991; mean CPM = 0.8041; wingless-type MMTV integration site family, member 9B" ID="ID_812357050" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Small cell lung cancer: Inhibited, FDR = 0.0118, FWER = 0.236, PValue = 0.00162" ID="ID_554540618" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="COL4A1: 7.03-fold Down; FDR = 1.47e-15; PValue = 1.34e-17; mean CPM = 3419; collagen, type IV, alpha 1" ID="ID_141491190" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMC1: 2.28-fold Down; FDR = 6.46e-13; PValue = 1.01e-14; mean CPM = 812.1; laminin, gamma 1 (formerly LAMB2)" ID="ID_846859600" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016591: 4.2-fold Down; FDR = 1.3e-11; PValue = 2.78e-13; mean CPM = 34.90; Uncharacterized protein" ID="ID_1925607768" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016587: 4.92-fold Down; FDR = 1.6e-11; PValue = 3.5e-13; mean CPM = 51.70; Uncharacterized protein" ID="ID_1247733553" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAV: 2.64-fold Down; FDR = 6.04e-11; PValue = 1.51e-12; mean CPM = 337.3; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)" ID="ID_758129698" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC2: 1.96-fold Up; FDR = 1.01e-10; PValue = 2.62e-12; mean CPM = 53.58; baculoviral IAP repeat-containing 2" ID="ID_1223834509" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA2: 2.84-fold Up; FDR = 7.38e-10; PValue = 2.42e-11; mean CPM = 176.3; integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)" ID="ID_1809419242" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1B: 1.64-fold Up; FDR = 1.22e-08; PValue = 5.39e-10; mean CPM = 32.96; Cyclin-dependent kinase inhibitor 1B; Uncharacterized protein" ID="ID_416160184" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_126769780" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RB1: 1.65-fold Up; FDR = 6.01e-08; PValue = 3.2e-09; mean CPM = 59.24; retinoblastoma 1" ID="ID_1367699414" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_386383166" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RARB: 2.64-fold Up; FDR = 9.11e-07; PValue = 6.49e-08; mean CPM = 8.811; Uncharacterized protein" ID="ID_1062834515" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L1: 1.51-fold Up; FDR = 9.13e-07; PValue = 6.52e-08; mean CPM = 66.15; Bcl-2-like protein 1; Bcl-2-like protein 1 isoform 1; Uncharacterized protein" ID="ID_1445088877" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_476853396" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_826971937" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC3: 2.79-fold Up; FDR = 1.74e-06; PValue = 1.32e-07; mean CPM = 95.34; baculoviral IAP repeat-containing 3" ID="ID_975966372" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL4A5: 2.03-fold Down; FDR = 3.06e-06; PValue = 2.48e-07; mean CPM = 9.810; collagen, type IV, alpha 5" ID="ID_898344989" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMC2: 2.28-fold Down; FDR = 9.83e-06; PValue = 9.24e-07; mean CPM = 16.99; laminin, gamma 2" ID="ID_977817189" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF1: 2.6-fold Down; FDR = 1.48e-05; PValue = 1.46e-06; mean CPM = 20.19; TNF receptor-associated factor 1" ID="ID_535324309" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTGS2: 2.02-fold Up; FDR = 0.000254; PValue = 3.59e-05; mean CPM = 314.5; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)" ID="ID_929305032" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CKS2: 1.46-fold Up; FDR = 0.000296; PValue = 4.24e-05; mean CPM = 35.30; CDC28 protein kinase regulatory subunit 2" ID="ID_718400119" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB2: 1.48-fold Down; FDR = 0.000398; PValue = 5.93e-05; mean CPM = 695.6; laminin, beta 2 (laminin S)" ID="ID_1295234702" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA3: 1.34-fold Down; FDR = 0.000518; PValue = 7.96e-05; mean CPM = 126.8; integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)" ID="ID_1260987453" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN2B: 1.63-fold Down; FDR = 0.000936; PValue = 0.000156; mean CPM = 17.34; cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)" ID="ID_1411930189" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_43784684" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAX: 1.28-fold Up; FDR = 0.00569; PValue = 0.00123; mean CPM = 29.78; MYC associated factor X" ID="ID_890824340" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FN1: 1.7-fold Down; FDR = 0.0164; PValue = 0.00417; mean CPM = 40317; fibronectin 1" ID="ID_443272575" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CKS2: 1.94-fold Up; FDR = 0.0164; PValue = 0.00419; mean CPM = 2.062; Cyclin-dependent kinases regulatory subunit 2; Uncharacterized protein" ID="ID_1049797650" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA2B: 1.71-fold Down; FDR = 0.0187; PValue = 0.00486; mean CPM = 2.655; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)" ID="ID_53342884" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK2: 1.23-fold Down; FDR = 0.0194; PValue = 0.00507; mean CPM = 36.76; cyclin-dependent kinase 2" ID="ID_548604650" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1994384980" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF4: 1.21-fold Down; FDR = 0.037; PValue = 0.0108; mean CPM = 29.95; TNF receptor-associated factor 4" ID="ID_1535078475" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_905539268" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="E2F1: 1.44-fold Down; FDR = 0.0425; PValue = 0.0127; mean CPM = 8.857; E2F transcription factor 1" ID="ID_96013743" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_596861089" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB1: 1.23-fold Up; FDR = 0.0759; PValue = 0.0253; mean CPM = 2700; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)" ID="ID_1594083799" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RXRA: 1.18-fold Down; FDR = 0.077; PValue = 0.0257; mean CPM = 35.60; retinoid X receptor, alpha" ID="ID_1146917641" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMA4: 1.2-fold Down; FDR = 0.0793; PValue = 0.0266; mean CPM = 624.4; laminin, alpha 4" ID="ID_1910976135" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_1676615286" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND1: 1.17-fold Up; FDR = 0.121; PValue = 0.0443; mean CPM = 867.3; cyclin D1" ID="ID_230294018" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTEN: 1.14-fold Up; FDR = 0.166; PValue = 0.065; mean CPM = 89.60; phosphatase and tensin homolog" ID="ID_904954472" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XIAP: 1.17-fold Up; FDR = 0.177; PValue = 0.0706; mean CPM = 19.21; X-linked inhibitor of apoptosis" ID="ID_1060927363" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XIAP: 1.26-fold Up; FDR = 0.192; PValue = 0.0778; mean CPM = 5.625; Uncharacterized protein" ID="ID_1683099816" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000039103: 1.67-fold Down; FDR = 0.221; PValue = 0.0927; mean CPM = 1.310; Uncharacterized protein" ID="ID_428283010" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB4: 1.81-fold Down; FDR = 0.237; PValue = 0.101; mean CPM = 1.043; laminin, beta 4" ID="ID_1888236841" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNE1: 1.2-fold Up; FDR = 0.278; PValue = 0.123; mean CPM = 6.609; cyclin E1" ID="ID_1475736133" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_780693109" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK6: 1.18-fold Down; FDR = 0.301; PValue = 0.136; mean CPM = 26.51; cyclin-dependent kinase 6" ID="ID_749265580" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014969: 1.93-fold Down; FDR = 0.303; PValue = 0.137; mean CPM = 0.9384; Uncharacterized protein" ID="ID_359615832" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB3: 1.6-fold Down; FDR = 0.303; PValue = 0.137; mean CPM = 1.445; laminin, beta 3" ID="ID_1483743096" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_382910280" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_437345458" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2: 1.1-fold Up; FDR = 0.394; PValue = 0.191; mean CPM = 102.5; PTK2 protein tyrosine kinase 2" ID="ID_1218734979" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL4A3: 1.67-fold Down; FDR = 0.422; PValue = 0.207; mean CPM = 0.9315; collagen, type IV, alpha 3 (Goodpasture antigen)" ID="ID_517766065" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_1237307462" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF3: 1.07-fold Up; FDR = 0.611; PValue = 0.338; mean CPM = 34.56; TNF receptor-associated factor 3" ID="ID_1979677160" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL4A6: 1.4-fold Down; FDR = 0.631; PValue = 0.353; mean CPM = 1.078; collagen, type IV, alpha 6" ID="ID_1608155545" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014966: 1.43-fold Down; FDR = 0.72; PValue = 0.423; mean CPM = 0.9009; Uncharacterized protein" ID="ID_267151830" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="E2F3: 1.08-fold Up; FDR = 0.751; PValue = 0.452; mean CPM = 11.79; E2F transcription factor 3" ID="ID_1813745113" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIAS2: 1.06-fold Down; FDR = 0.807; PValue = 0.503; mean CPM = 19.53; protein inhibitor of activated STAT, 2" ID="ID_1445629114" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APAF1: 1.05-fold Down; FDR = 0.837; PValue = 0.543; mean CPM = 32.11; apoptotic peptidase activating factor 1" ID="ID_326358759" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYCS: 1.05-fold Up; FDR = 0.854; PValue = 0.565; mean CPM = 93.43; cytochrome c, somatic" ID="ID_368002305" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1965041907" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000040219: 1.08-fold Up; FDR = 0.86; PValue = 0.575; mean CPM = 8.818; Uncharacterized protein" ID="ID_372831324" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC7: 1.52-fold Down; FDR = 0.881; PValue = 0.601; mean CPM = 0.8439; baculoviral IAP repeat containing 7" ID="ID_1286996695" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK4: 1.04-fold Up; FDR = 0.899; PValue = 0.626; mean CPM = 65.45; cyclin-dependent kinase 4" ID="ID_1655941107" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RXRG: 1.32-fold Up; FDR = 0.915; PValue = 0.714; mean CPM = 0.8688; retinoid X receptor, gamma" ID="ID_1471287250" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOS2: 1.4-fold Down; FDR = 0.917; PValue = 0.718; mean CPM = 0.8546; nitric oxide synthase 2, inducible" ID="ID_418908540" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNE2: 1.05-fold Up; FDR = 0.962; PValue = 0.796; mean CPM = 6.415; cyclin E2" ID="ID_1840794268" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000009289: 1.07-fold Up; FDR = 0.963; PValue = 0.798; mean CPM = 2.536; Uncharacterized protein" ID="ID_174868541" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="E2F2: 1.03-fold Up; FDR = 1; PValue = 0.906; mean CPM = 1.976; E2F transcription factor 2" ID="ID_1810272999" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP9: 1.01-fold Up; FDR = 1; PValue = 0.908; mean CPM = 19.86; caspase 9, apoptosis-related cysteine peptidase" ID="ID_69847066" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Cytosolic DNA-sensing pathway: Activated, FDR = 0.0151, FWER = 0.316, PValue = 0.00218" ID="ID_1543881079" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="AIM2: 7.87-fold Up; FDR = 4.34e-20; PValue = 1.57e-22; mean CPM = 34.80; absent in melanoma 2" ID="ID_504959887" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DDX58: 6.4-fold Up; FDR = 5.12e-18; PValue = 3.06e-20; mean CPM = 86.14; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58" ID="ID_1003996697" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF7: 14.8-fold Up; FDR = 7.66e-18; PValue = 4.82e-20; mean CPM = 11.54; Macaca mulatta interferon regulatory factor 7 (IRF7), mRNA." ID="ID_1903060925" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK3: 3.47-fold Up; FDR = 2.3e-12; PValue = 4.07e-14; mean CPM = 12.05; receptor-interacting serine-threonine kinase 3" ID="ID_963319936" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MB21D1: 3.62-fold Up; FDR = 5.31e-10; PValue = 1.69e-11; mean CPM = 10.27; Mab-21 domain containing 1" ID="ID_1884633202" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAVS: 1.92-fold Down; FDR = 2.7e-09; PValue = 1.02e-10; mean CPM = 29.16; mitochondrial antiviral signaling protein" ID="ID_1099078436" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_1337989127" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1497662419" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZBP1: 4.36-fold Up; FDR = 0.00021; PValue = 2.88e-05; mean CPM = 1.491; Z-DNA binding protein 1" ID="ID_1639659468" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBK1: 1.3-fold Up; FDR = 0.00337; PValue = 0.000674; mean CPM = 30.46; TANK-binding kinase 1" ID="ID_540229673" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_578122760" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMEM173: 1.25-fold Up; FDR = 0.00837; PValue = 0.00192; mean CPM = 219.1; transmembrane protein 173" ID="ID_1741029346" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1380718994" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_384203643" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PYCARD: 1.38-fold Down; FDR = 0.241; PValue = 0.103; mean CPM = 3.110; PYD and CARD domain containing" ID="ID_356506451" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1114634906" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKE: 1.03-fold Up; FDR = 0.929; PValue = 0.737; mean CPM = 21.61; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon" ID="ID_1720236551" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_1282009307" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg NF-kappa B signaling pathway: Activated, FDR = 0.0176, FWER = 0.386, PValue = 0.00266" ID="ID_1051914504" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TNFSF13B: 123-fold Up; FDR = 9.32e-25; PValue = 7.44e-28; mean CPM = 49.02; tumor necrosis factor (ligand) superfamily, member 13b" ID="ID_1816904820" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRIM25: 3.78-fold Up; FDR = 3.13e-19; PValue = 1.41e-21; mean CPM = 121.6; tripartite motif-containing 25" ID="ID_918054286" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DDX58: 6.4-fold Up; FDR = 5.12e-18; PValue = 3.06e-20; mean CPM = 86.14; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58" ID="ID_1119312477" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICAM1: 24.6-fold Up; FDR = 2.39e-17; PValue = 1.64e-19; mean CPM = 232.4; intercellular adhesion molecule 1" ID="ID_340996797" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC2: 1.96-fold Up; FDR = 1.01e-10; PValue = 2.62e-12; mean CPM = 53.58; baculoviral IAP repeat-containing 2" ID="ID_1237513308" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLAU: 3.37-fold Down; FDR = 1.56e-10; PValue = 4.33e-12; mean CPM = 18.78; plasminogen activator, urokinase" ID="ID_1046612221" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL13: 12.3-fold Up; FDR = 4.33e-10; PValue = 1.35e-11; mean CPM = 3.824; chemokine (C-C motif) ligand 13" ID="ID_354901599" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CFLAR: 1.87-fold Up; FDR = 5.09e-10; PValue = 1.61e-11; mean CPM = 103.3; CASP8 and FADD-like apoptosis regulator" ID="ID_1643436826" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2A1: 5.05-fold Up; FDR = 1.06e-09; PValue = 3.61e-11; mean CPM = 10.70; BCL2-related protein A1" ID="ID_747483551" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR4: 3.45-fold Up; FDR = 3.1e-09; PValue = 1.19e-10; mean CPM = 7.456; Macaca mulatta toll-like receptor 4 (TLR4), mRNA." ID="ID_765099147" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_580734340" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK4: 1.8-fold Up; FDR = 3.31e-08; PValue = 1.64e-09; mean CPM = 12.89; interleukin-1 receptor-associated kinase 4" ID="ID_590958042" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1910899885" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD14: 2.75-fold Down; FDR = 6.54e-07; PValue = 4.46e-08; mean CPM = 5.195; CD14 molecule" ID="ID_48752457" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L1: 1.51-fold Up; FDR = 9.13e-07; PValue = 6.52e-08; mean CPM = 66.15; Bcl-2-like protein 1; Bcl-2-like protein 1 isoform 1; Uncharacterized protein" ID="ID_1192538570" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC3: 2.79-fold Up; FDR = 1.74e-06; PValue = 1.32e-07; mean CPM = 95.34; baculoviral IAP repeat-containing 3" ID="ID_1273226310" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF1: 2.6-fold Down; FDR = 1.48e-05; PValue = 1.46e-06; mean CPM = 20.19; TNF receptor-associated factor 1" ID="ID_1814763463" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFAIP3: 1.79-fold Up; FDR = 3.14e-05; PValue = 3.34e-06; mean CPM = 52.47; tumor necrosis factor, alpha-induced protein 3" ID="ID_1306229024" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1R1: 1.6-fold Up; FDR = 3.35e-05; PValue = 3.61e-06; mean CPM = 123.7; interleukin 1 receptor, type I" ID="ID_1509046582" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_541272263" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP2: 1.45-fold Up; FDR = 0.000179; PValue = 2.4e-05; mean CPM = 65.31; TGF-beta activated kinase 1/MAP3K7 binding protein 2" ID="ID_209738911" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTGS2: 2.02-fold Up; FDR = 0.000254; PValue = 3.59e-05; mean CPM = 314.5; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)" ID="ID_429181286" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP3: 1.5-fold Up; FDR = 0.000276; PValue = 3.92e-05; mean CPM = 11.67; TGF-beta activated kinase 1/MAP3K7 binding protein 3" ID="ID_1501701641" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40: 2.76-fold Up; FDR = 0.00039; PValue = 5.79e-05; mean CPM = 9.139; CD40 molecule, TNF receptor superfamily member 5" ID="ID_629429446" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG1: 1.31-fold Down; FDR = 0.00352; PValue = 0.000707; mean CPM = 53.66; phospholipase C, gamma 1" ID="ID_1103835532" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1588284563" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K14: 1.47-fold Down; FDR = 0.00704; PValue = 0.00157; mean CPM = 9.470; mitogen-activated protein kinase kinase kinase 14" ID="ID_120936321" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GADD45B: 1.49-fold Down; FDR = 0.0082; PValue = 0.00187; mean CPM = 175.6; growth arrest and DNA-damage-inducible, beta" ID="ID_1137543859" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BLNK: 2.61-fold Up; FDR = 0.012; PValue = 0.00288; mean CPM = 1.254; Uncharacterized protein" ID="ID_1137926247" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSNK2A2: 1.28-fold Up; FDR = 0.0129; PValue = 0.00314; mean CPM = 19.86; casein kinase 2, alpha prime polypeptide" ID="ID_787755789" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL8: 2.33-fold Up; FDR = 0.0209; PValue = 0.00552; mean CPM = 2326; interleukin 8" ID="ID_1453970760" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CARD11: 1.31-fold Down; FDR = 0.0223; PValue = 0.00597; mean CPM = 58.32; caspase recruitment domain family, member 11" ID="ID_735735330" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRADD: 1.22-fold Up; FDR = 0.0319; PValue = 0.00907; mean CPM = 34.75; TNFRSF1A-associated via death domain" ID="ID_1123447045" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VCAM1: 1.53-fold Up; FDR = 0.0353; PValue = 0.0102; mean CPM = 110.0; vascular cell adhesion molecule 1" ID="ID_1970152223" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF11: 1.8-fold Up; FDR = 0.039; PValue = 0.0115; mean CPM = 2.535; tumor necrosis factor (ligand) superfamily, member 11" ID="ID_892364670" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_648993807" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELB: 1.22-fold Down; FDR = 0.0606; PValue = 0.0193; mean CPM = 26.64; v-rel reticuloendotheliosis viral oncogene homolog B" ID="ID_27486544" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_578904072" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XIAP: 1.17-fold Up; FDR = 0.177; PValue = 0.0706; mean CPM = 19.21; X-linked inhibitor of apoptosis" ID="ID_617571678" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAT: 1.44-fold Down; FDR = 0.234; PValue = 0.0996; mean CPM = 1.871; linker for activation of T cells" ID="ID_204318018" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1A: 1.11-fold Up; FDR = 0.297; PValue = 0.134; mean CPM = 134.7; tumor necrosis factor receptor superfamily, member 1A" ID="ID_206845188" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP1: 1.12-fold Down; FDR = 0.351; PValue = 0.165; mean CPM = 17.96; TGF-beta activated kinase 1/MAP3K7 binding protein 1" ID="ID_492536975" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2: 1.48-fold Up; FDR = 0.384; PValue = 0.184; mean CPM = 1.344; Uncharacterized protein" ID="ID_689786061" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TICAM1: 1.11-fold Down; FDR = 0.398; PValue = 0.192; mean CPM = 26.73; toll-like receptor adaptor molecule 1" ID="ID_1217629956" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL12: 1.27-fold Down; FDR = 0.488; PValue = 0.251; mean CPM = 4.383; chemokine (C-X-C motif) ligand 12" ID="ID_277574773" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCQ: 1.56-fold Up; FDR = 0.522; PValue = 0.274; mean CPM = 1.047; Uncharacterized protein" ID="ID_985797385" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF3: 1.07-fold Up; FDR = 0.611; PValue = 0.338; mean CPM = 34.56; TNF receptor-associated factor 3" ID="ID_1954737331" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_393340502" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF11A: 1.4-fold Down; FDR = 0.676; PValue = 0.388; mean CPM = 0.9723; tumor necrosis factor receptor superfamily, member 11a, NFKB activator" ID="ID_621150884" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LTBR: 1.06-fold Down; FDR = 0.683; PValue = 0.394; mean CPM = 91.13; lymphotoxin beta receptor (TNFR superfamily, member 3)" ID="ID_363636130" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCB: 1.86-fold Up; FDR = 0.727; PValue = 0.43; mean CPM = 0.8705; protein kinase C, beta" ID="ID_1868268195" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TIRAP: 1.07-fold Up; FDR = 0.841; PValue = 0.548; mean CPM = 8.693; Macaca mulatta toll-interleukin 1 receptor (TIR) domain containing adaptor protein (TIRAP), mRNA." ID="ID_288970946" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_198669572" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZAP70: 1.25-fold Down; FDR = 0.872; PValue = 0.59; mean CPM = 0.8996; zeta-chain (TCR) associated protein kinase 70kDa" ID="ID_165471540" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK1: 1.04-fold Down; FDR = 0.885; PValue = 0.606; mean CPM = 41.54; interleukin-1 receptor-associated kinase 1" ID="ID_582878945" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_1859681538" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF14: 1.16-fold Down; FDR = 0.903; PValue = 0.645; mean CPM = 0.7940; tumor necrosis factor (ligand) superfamily, member 14" ID="ID_525009163" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSNK2B: 1.02-fold Down; FDR = 0.956; PValue = 0.787; mean CPM = 77.24; Casein kinase II subunit beta (CK II beta)(Phosvitin)(Protein G5a)" ID="ID_1017103469" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL21: 1.09-fold Down; FDR = 0.972; PValue = 0.813; mean CPM = 1.083; chemokine (C-C motif) ligand 21" ID="ID_594857798" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_1660769958" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG2: 1.06-fold Up; FDR = 0.985; PValue = 0.834; mean CPM = 2.248; phospholipase C, gamma 2 (phosphatidylinositol-specific)" ID="ID_1173423924" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LTB: 1.01-fold Up; FDR = 1; PValue = 0.935; mean CPM = 0.8459; Lymphotoxin-beta (LT-beta)(Tumor necrosis factor C)(TNF-C)(Tumor necrosis factor ligand superfamily member 3)" ID="ID_1881278515" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BTK: No Change; FDR = 1; PValue = 0.965; mean CPM = 0.8336; Bruton agammaglobulinemia tyrosine kinase" ID="ID_759357534" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SYK: 1.11-fold Up; FDR = 1; PValue = 0.977; mean CPM = 0.8420; spleen tyrosine kinase" ID="ID_1154837895" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40LG: 1.01-fold Down; FDR = 1; PValue = 0.982; mean CPM = 0.8653; CD40 ligand" ID="ID_737717736" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Cell adhesion molecules (CAMs): Activated, FDR = 0.025, FWER = 0.575, PValue = 0.00397" ID="ID_585411762" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="ENSMMUP00000027180: 6.97-fold Up; FDR = 1.24e-21; PValue = 3.39e-24; mean CPM = 285.4; Uncharacterized protein" ID="ID_1802628783" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000027180: 6.97-fold Up; FDR = 1.24e-21; PValue = 3.39e-24; mean CPM = 285.4; Uncharacterized protein" ID="ID_1853727461" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000005183: 4.07-fold Up; FDR = 2.87e-21; PValue = 8.51e-24; mean CPM = 164.7; Uncharacterized protein" ID="ID_1916467609" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000005183: 4.07-fold Up; FDR = 2.87e-21; PValue = 8.51e-24; mean CPM = 164.7; Uncharacterized protein" ID="ID_1538150659" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD274: 21.5-fold Up; FDR = 4.64e-21; PValue = 1.39e-23; mean CPM = 62.62; Macaca mulatta CD274 molecule (CD274), mRNA." ID="ID_1645212185" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-B: 6.07-fold Up; FDR = 2.71e-19; PValue = 1.2e-21; mean CPM = 2098; Uncharacterized protein" ID="ID_956038688" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICAM1: 24.6-fold Up; FDR = 2.39e-17; PValue = 1.64e-19; mean CPM = 232.4; intercellular adhesion molecule 1" ID="ID_1828590574" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DMB: 17.5-fold Up; FDR = 2.77e-15; PValue = 2.66e-17; mean CPM = 9.464; HLA class II histocompatibility antigen, DM beta chain Precursor (MHC class II antigen DMB)(Really interesting new gene 7 protein)" ID="ID_1388278650" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DPA1: 107-fold Up; FDR = 5.97e-15; PValue = 6.11e-17; mean CPM = 17.08; HLA class II histocompatibility antigen, DP alpha 1 chain Precursor (HLA-SB alpha chain)(MHC class II DP3-alpha)(DP(W3))(DP(W4))" ID="ID_663702873" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDCD1LG2: 5.48-fold Up; FDR = 1.11e-13; PValue = 1.46e-15; mean CPM = 28.34; programmed cell death 1 ligand 2" ID="ID_281496335" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DQB1: 31.1-fold Up; FDR = 6.93e-13; PValue = 1.1e-14; mean CPM = 6.675; Macaca mulatta MHC class II antigen (MAMU-DRB), mRNA." ID="ID_1089508376" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPRF: 2.51-fold Down; FDR = 5.51e-10; PValue = 1.77e-11; mean CPM = 184.0; protein tyrosine phosphatase, receptor type, F" ID="ID_1398925452" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CNTNAP1: 2.24-fold Down; FDR = 1.39e-08; PValue = 6.26e-10; mean CPM = 15.44; contactin associated protein 1" ID="ID_1600826279" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAM3: 1.66-fold Down; FDR = 1.46e-08; PValue = 6.62e-10; mean CPM = 47.05; junctional adhesion molecule 3" ID="ID_872678401" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA1: 15.1-fold Up; FDR = 1.9e-08; PValue = 8.86e-10; mean CPM = 3.665; HLA class II histocompatibility antigen, DQ alpha 1 chain precursor" ID="ID_466074180" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DPB1: 7.73-fold Up; FDR = 4.73e-08; PValue = 2.45e-09; mean CPM = 1.528; Macaca mulatta major histocompatibility complex, class II, DP beta (MAMU-DPB), mRNA." ID="ID_701011547" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLGN2: 1.64-fold Down; FDR = 6.24e-05; PValue = 7.29e-06; mean CPM = 14.59; neuroligin 2" ID="ID_337499776" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPRC: 6.08-fold Up; FDR = 0.000285; PValue = 4.07e-05; mean CPM = 1.220; protein tyrosine phosphatase, receptor type, C" ID="ID_1549508942" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40: 2.76-fold Up; FDR = 0.00039; PValue = 5.79e-05; mean CPM = 9.139; CD40 molecule, TNF receptor superfamily member 5" ID="ID_1684582441" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NRCAM: 2.04-fold Down; FDR = 0.00042; PValue = 6.29e-05; mean CPM = 7.571; Uncharacterized protein" ID="ID_1463492320" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD34: 2.84-fold Up; FDR = 0.000647; PValue = 0.000102; mean CPM = 1.700; CD34 molecule" ID="ID_1935074686" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GLG1: 1.28-fold Down; FDR = 0.00336; PValue = 0.000671; mean CPM = 229.6; golgi glycoprotein 1" ID="ID_827000984" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NTNG2: 1.72-fold Up; FDR = 0.00821; PValue = 0.00187; mean CPM = 4.362; Uncharacterized protein" ID="ID_867434689" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NRXN2: 3.89-fold Down; FDR = 0.0116; PValue = 0.0028; mean CPM = 1.629; neurexin 2" ID="ID_39436980" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SELE: 4.04-fold Down; FDR = 0.0118; PValue = 0.00285; mean CPM = 0.9962; selectin E" ID="ID_1456949858" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CNTN1: 2.61-fold Down; FDR = 0.0121; PValue = 0.00294; mean CPM = 1.505; contactin 1" ID="ID_244741539" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NTNG1: 2.36-fold Down; FDR = 0.0143; PValue = 0.00357; mean CPM = 1.724; netrin G1" ID="ID_738957588" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB2: 1.55-fold Down; FDR = 0.0187; PValue = 0.00485; mean CPM = 34.87; Integrin beta" ID="ID_1563581236" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VCAM1: 1.53-fold Up; FDR = 0.0353; PValue = 0.0102; mean CPM = 110.0; vascular cell adhesion molecule 1" ID="ID_282908366" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PVRL3: 1.22-fold Up; FDR = 0.037; PValue = 0.0108; mean CPM = 29.58; poliovirus receptor-related 3" ID="ID_1168032815" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CNTN2: 2.73-fold Down; FDR = 0.0614; PValue = 0.0196; mean CPM = 0.9153; contactin 2 (axonal)" ID="ID_647251181" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DOA: 2.74-fold Up; FDR = 0.0694; PValue = 0.0227; mean CPM = 0.9089; HLA class II histocompatibility antigen, DO alpha chain Precursor (MHC class II antigen DOA)(MHC DZ alpha)(MHC DN-alpha)" ID="ID_1334779009" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB1: 1.23-fold Up; FDR = 0.0759; PValue = 0.0253; mean CPM = 2700; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)" ID="ID_900347694" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLGN1: 1.91-fold Down; FDR = 0.0998; PValue = 0.0349; mean CPM = 1.272; neuroligin 1" ID="ID_1569502260" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="F11R: 1.41-fold Down; FDR = 0.113; PValue = 0.0407; mean CPM = 11.52; Uncharacterized protein" ID="ID_1484158850" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PVRL1: 1.47-fold Down; FDR = 0.119; PValue = 0.0431; mean CPM = 2.907; poliovirus receptor-related 1 (herpesvirus entry mediator C)" ID="ID_1055731140" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPN: 2.27-fold Down; FDR = 0.157; PValue = 0.0608; mean CPM = 0.9319; sialophorin" ID="ID_612921414" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ALCAM: 1.26-fold Down; FDR = 0.234; PValue = 0.0995; mean CPM = 41.17; activated leukocyte cell adhesion molecule" ID="ID_1965378187" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014796: 1.77-fold Up; FDR = 0.381; PValue = 0.182; mean CPM = 0.9085; Uncharacterized protein" ID="ID_944298463" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CNTNAP2: 1.48-fold Down; FDR = 0.515; PValue = 0.268; mean CPM = 1.160; contactin associated protein-like 2" ID="ID_1023868260" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PVRL2: 1.08-fold Down; FDR = 0.552; PValue = 0.295; mean CPM = 35.47; poliovirus receptor-related 2 (herpesvirus entry mediator B)" ID="ID_370733366" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA9: 1.3-fold Down; FDR = 0.595; PValue = 0.326; mean CPM = 1.685; integrin, alpha 9" ID="ID_184523526" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="L1CAM: 1.34-fold Down; FDR = 0.601; PValue = 0.331; mean CPM = 2.064; Uncharacterized protein" ID="ID_1635282376" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICAM3: 1.1-fold Down; FDR = 0.685; PValue = 0.395; mean CPM = 7.797; intercellular adhesion molecule 3" ID="ID_371616411" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA4: 1.16-fold Down; FDR = 0.722; PValue = 0.425; mean CPM = 5.425; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)" ID="ID_862156611" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAM: 1.44-fold Down; FDR = 0.73; PValue = 0.432; mean CPM = 0.9052; integrin, alpha M (complement component 3 receptor 3 subunit)" ID="ID_399690582" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLGN3: 1.27-fold Down; FDR = 0.783; PValue = 0.48; mean CPM = 1.180; neuroligin 3" ID="ID_954013505" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD4: 1.27-fold Up; FDR = 0.807; PValue = 0.503; mean CPM = 1.122; CD4 molecule" ID="ID_463567192" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTLA4: 1.41-fold Down; FDR = 0.827; PValue = 0.527; mean CPM = 0.8017; cytotoxic T-lymphocyte-associated protein 4" ID="ID_575341146" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICAM2: 1.26-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 0.9289; intercellular adhesion molecule 2" ID="ID_18947648" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD58: 1.04-fold Down; FDR = 0.889; PValue = 0.612; mean CPM = 21.84; CD58 molecule" ID="ID_1780723135" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DRB: 1.28-fold Up; FDR = 0.898; PValue = 0.624; mean CPM = 0.8112; MHC class II antigen; Uncharacterized protein" ID="ID_81114275" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SIGLEC1: 1.23-fold Down; FDR = 0.899; PValue = 0.626; mean CPM = 0.9801; sialic acid binding Ig-like lectin 1, sialoadhesin" ID="ID_571164534" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD2: 1.42-fold Up; FDR = 0.903; PValue = 0.641; mean CPM = 0.8179; CD2 molecule" ID="ID_1090821322" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDCD1: 1.5-fold Down; FDR = 0.903; PValue = 0.644; mean CPM = 0.8258; programmed cell death 1" ID="ID_242607980" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000024680: 1.21-fold Down; FDR = 0.903; PValue = 0.647; mean CPM = 0.7890; Uncharacterized protein" ID="ID_1691770033" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LRRC4C: 1.2-fold Up; FDR = 0.906; PValue = 0.671; mean CPM = 0.7955; leucine rich repeat containing 4C" ID="ID_67890644" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA2: 1.13-fold Up; FDR = 0.908; PValue = 0.681; mean CPM = 0.7877; HLA class II histocompatibility antigen, DQ alpha 2 chain Precursor (HLA class II histocompatibility antigen, DQ(6) alpha chain)(DX alpha chain)(HLA-DQA1)" ID="ID_1019386952" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICOSLG: 1.07-fold Down; FDR = 0.909; PValue = 0.684; mean CPM = 6.739; inducible T-cell co-stimulator ligand" ID="ID_1251197871" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MADCAM1: 1.11-fold Up; FDR = 0.909; PValue = 0.688; mean CPM = 0.7934; mucosal vascular addressin cell adhesion molecule 1" ID="ID_618108471" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TIGIT: 1.16-fold Up; FDR = 0.911; PValue = 0.706; mean CPM = 1.019; T cell immunoreceptor with Ig and ITIM domains" ID="ID_957076773" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICOS: 1.19-fold Up; FDR = 0.931; PValue = 0.741; mean CPM = 0.8158; Uncharacterized protein" ID="ID_1196153195" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD6: 1.11-fold Up; FDR = 0.931; PValue = 0.742; mean CPM = 1.320; CD6 molecule" ID="ID_1292523070" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SELP: 1.2-fold Down; FDR = 0.942; PValue = 0.76; mean CPM = 0.8693; selectin P (granule membrane protein 140kDa, antigen CD62)" ID="ID_284819549" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD80: 1.08-fold Up; FDR = 0.971; PValue = 0.812; mean CPM = 1.157; CD80 molecule" ID="ID_1474648336" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD22: 1.18-fold Down; FDR = 1; PValue = 0.928; mean CPM = 0.8572; CD22 molecule" ID="ID_143894117" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAL: 1.03-fold Up; FDR = 1; PValue = 0.95; mean CPM = 1.035; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)" ID="ID_1127557322" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB7: 1.01-fold Down; FDR = 1; PValue = 0.968; mean CPM = 2.025; integrin, beta 7" ID="ID_108734666" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD8A: No Change; FDR = 1; PValue = 0.98; mean CPM = 0.8052; CD8a molecule" ID="ID_467687618" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40LG: 1.01-fold Down; FDR = 1; PValue = 0.982; mean CPM = 0.8653; CD40 ligand" ID="ID_1462533830" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD86: 1.01-fold Down; FDR = 1; PValue = 0.99; mean CPM = 0.8012; CD86 molecule" ID="ID_991577238" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SELL: 1.04-fold Up; FDR = 1; PValue = 0.995; mean CPM = 0.8177; Macaca mulatta selectin L (SELL), mRNA." ID="ID_787220691" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NRXN1: 1.07-fold Up; FDR = 1; PValue = 0.999; mean CPM = 0.8440; neurexin 1" ID="ID_1009581355" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD226: No Change; FDR = 1; PValue = 1; mean CPM = 0.7800; CD226 molecule" ID="ID_1677763001" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg MAPK signaling pathway: Activated, FDR = 0.0251, FWER = 0.617, PValue = 0.00426" ID="ID_694390264" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="PLA2G4C: 15.2-fold Up; FDR = 1.43e-17; PValue = 9.52e-20; mean CPM = 117.2; phospholipase A2, group IVC (cytosolic, calcium-independent)" ID="ID_961348325" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MRAS: 2.04-fold Up; FDR = 4.47e-15; PValue = 4.43e-17; mean CPM = 41.38; muscle RAS oncogene homolog" ID="ID_1671106183" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA2: 4.21-fold Down; FDR = 2.4e-14; PValue = 2.77e-16; mean CPM = 66.42; heat shock 70kDa protein 2" ID="ID_1903393227" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFRA: 2.76-fold Up; FDR = 3.93e-14; PValue = 4.67e-16; mean CPM = 492.9; platelet-derived growth factor receptor, alpha polypeptide" ID="ID_1218985460" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF1: 5.05-fold Down; FDR = 8.21e-14; PValue = 1.05e-15; mean CPM = 19.54; fibroblast growth factor 1 (acidic)" ID="ID_361694491" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASGRP3: 7.1-fold Up; FDR = 6.93e-13; PValue = 1.1e-14; mean CPM = 7.525; RAS guanyl releasing protein 3 (calcium and DAG-regulated)" ID="ID_104650888" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB3: 4.82-fold Down; FDR = 1.82e-12; PValue = 3.09e-14; mean CPM = 9.911; transforming growth factor, beta 3" ID="ID_1702002378" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SRF: 1.69-fold Down; FDR = 8.07e-11; PValue = 2.06e-12; mean CPM = 34.61; serum response factor (c-fos serum response element-binding transcription factor)" ID="ID_770055030" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA1B: 2.24-fold Down; FDR = 4.33e-09; PValue = 1.71e-10; mean CPM = 44.90; Heat shock 70 kDa protein 1A/1B (Heat shock 70 kDa protein 1/2)(HSP70.1/HSP70.2)(HSP70-1/HSP70-2)" ID="ID_588448496" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_1092347682" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGFR: 1.84-fold Up; FDR = 6.71e-09; PValue = 2.77e-10; mean CPM = 68.58; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)" ID="ID_557781960" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF2: 2.42-fold Up; FDR = 9.98e-09; PValue = 4.31e-10; mean CPM = 134.8; fibroblast growth factor 2 (basic)" ID="ID_1824706092" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGFR2: 3.45-fold Down; FDR = 1.04e-08; PValue = 4.53e-10; mean CPM = 5.064; fibroblast growth factor receptor 2" ID="ID_1038227470" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA8: 1.64-fold Up; FDR = 1.46e-08; PValue = 6.6e-10; mean CPM = 1881; heat shock 70kDa protein 8" ID="ID_536905203" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FLNA: 2.35-fold Down; FDR = 2.01e-08; PValue = 9.45e-10; mean CPM = 7159; filamin A, alpha" ID="ID_1435566911" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DUSP7: 1.77-fold Down; FDR = 3.08e-08; PValue = 1.52e-09; mean CPM = 22.67; dual specificity phosphatase 7" ID="ID_1360610558" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_241944133" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1B: 1.55-fold Up; FDR = 2.39e-07; PValue = 1.46e-08; mean CPM = 135.3; Ras-related protein Rap-1b; Ras-related protein Rap-1b isoform 1; Uncharacterized protein" ID="ID_1949404236" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K6: 2.05-fold Down; FDR = 2.49e-07; PValue = 1.53e-08; mean CPM = 17.57; Uncharacterized protein" ID="ID_147413838" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFA: 1.92-fold Down; FDR = 2.56e-07; PValue = 1.58e-08; mean CPM = 22.99; platelet-derived growth factor alpha polypeptide" ID="ID_297590935" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_1768393761" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNA1C: 2.79-fold Down; FDR = 3.33e-07; PValue = 2.1e-08; mean CPM = 34.91; Uncharacterized protein" ID="ID_1041956609" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8IP1: 1.53-fold Down; FDR = 4.63e-07; PValue = 3.04e-08; mean CPM = 28.91; mitogen-activated protein kinase 8 interacting protein 1" ID="ID_1266210160" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD14: 2.75-fold Down; FDR = 6.54e-07; PValue = 4.46e-08; mean CPM = 5.195; CD14 molecule" ID="ID_1657780232" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FLNB: 1.64-fold Down; FDR = 1.25e-06; PValue = 9.2e-08; mean CPM = 1975; filamin B, beta" ID="ID_82758256" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DDIT3: 2.05-fold Up; FDR = 1.46e-06; PValue = 1.09e-07; mean CPM = 45.52; DNA-damage-inducible transcript 3" ID="ID_201300280" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_411576818" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_125782960" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DUSP5: 1.66-fold Up; FDR = 2.33e-06; PValue = 1.84e-07; mean CPM = 66.43; dual specificity phosphatase 5" ID="ID_1762121758" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGFR3: 3.85-fold Down; FDR = 2.66e-06; PValue = 2.13e-07; mean CPM = 2.800; fibroblast growth factor receptor 3" ID="ID_1926257644" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC3: 1.68-fold Down; FDR = 2.72e-06; PValue = 2.19e-07; mean CPM = 13.98; ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)" ID="ID_1015683183" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STK4: 1.47-fold Up; FDR = 3.87e-06; PValue = 3.24e-07; mean CPM = 35.55; serine/threonine kinase 4" ID="ID_864105442" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K3: 1.45-fold Down; FDR = 7.01e-06; PValue = 6.34e-07; mean CPM = 180.1; mitogen-activated protein kinase kinase 3" ID="ID_705393921" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FLNC: 1.74-fold Down; FDR = 7.81e-06; PValue = 7.15e-07; mean CPM = 868.2; filamin C, gamma" ID="ID_1787127350" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8IP3: 1.77-fold Down; FDR = 1.28e-05; PValue = 1.24e-06; mean CPM = 65.23; mitogen-activated protein kinase 8 interacting protein 3" ID="ID_700736496" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA5: 3.28-fold Up; FDR = 1.4e-05; PValue = 1.36e-06; mean CPM = 2.288; ribosomal protein S6 kinase, 90kDa, polypeptide 5" ID="ID_1552084205" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1097062849" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASGRF2: 5.55-fold Up; FDR = 2.4e-05; PValue = 2.48e-06; mean CPM = 2.163; Ras protein-specific guanine nucleotide-releasing factor 2" ID="ID_1602851174" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP4K4: 1.4-fold Down; FDR = 3.08e-05; PValue = 3.27e-06; mean CPM = 242.8; mitogen-activated protein kinase kinase kinase kinase 4" ID="ID_44798706" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPT: 2.89-fold Down; FDR = 3.14e-05; PValue = 3.34e-06; mean CPM = 2.105; microtubule-associated protein tau" ID="ID_669155377" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1R1: 1.6-fold Up; FDR = 3.35e-05; PValue = 3.61e-06; mean CPM = 123.7; interleukin 1 receptor, type I" ID="ID_729267929" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K5: 1.55-fold Up; FDR = 7.6e-05; PValue = 9.12e-06; mean CPM = 16.82; mitogen-activated protein kinase kinase 5" ID="ID_1240479966" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_374268720" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACA: 1.36-fold Down; FDR = 0.000167; PValue = 2.22e-05; mean CPM = 37.75; protein kinase, cAMP-dependent, catalytic, alpha" ID="ID_1129054346" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP2: 1.45-fold Up; FDR = 0.000179; PValue = 2.4e-05; mean CPM = 65.31; TGF-beta activated kinase 1/MAP3K7 binding protein 2" ID="ID_1043829179" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP3CA: 1.55-fold Up; FDR = 0.0003; PValue = 4.32e-05; mean CPM = 40.21; protein phosphatase 3, catalytic subunit, alpha isozyme" ID="ID_1554605454" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASGRP2: 2.4-fold Up; FDR = 0.000359; PValue = 5.28e-05; mean CPM = 5.834; Uncharacterized protein" ID="ID_957769883" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF2: 1.34-fold Up; FDR = 0.000403; PValue = 6.01e-05; mean CPM = 39.83; activating transcription factor 2" ID="ID_1620190039" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_1057856016" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DUSP8: 2.67-fold Down; FDR = 0.000451; PValue = 6.82e-05; mean CPM = 1.827; Uncharacterized protein" ID="ID_856880903" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ELK4: 1.37-fold Up; FDR = 0.000508; PValue = 7.78e-05; mean CPM = 24.59; ELK4, ETS-domain protein (SRF accessory protein 1)" ID="ID_108456295" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP4K2: 1.36-fold Down; FDR = 0.000898; PValue = 0.000149; mean CPM = 21.71; mitogen-activated protein kinase kinase kinase kinase 2" ID="ID_1133715494" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNA12: 1.32-fold Down; FDR = 0.000955; PValue = 0.00016; mean CPM = 33.75; Uncharacterized protein" ID="ID_184283421" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPM1A: 1.31-fold Up; FDR = 0.00101; PValue = 0.00017; mean CPM = 60.08; protein phosphatase, Mg2+/Mn2+ dependent, 1A" ID="ID_1549075518" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NR4A1: 1.74-fold Down; FDR = 0.00108; PValue = 0.000184; mean CPM = 312.6; nuclear receptor subfamily 4, group A, member 1" ID="ID_765864255" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DUSP1: 1.39-fold Down; FDR = 0.00173; PValue = 0.000315; mean CPM = 355.2; dual specificity phosphatase 1" ID="ID_346267901" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPM1B: 1.36-fold Up; FDR = 0.00193; PValue = 0.000358; mean CPM = 16.96; protein phosphatase, Mg2+/Mn2+ dependent, 1B" ID="ID_1916751169" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NGF: 1.32-fold Up; FDR = 0.00212; PValue = 0.000396; mean CPM = 198.5; nerve growth factor (beta polypeptide)" ID="ID_471037337" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF4: 1.29-fold Up; FDR = 0.00296; PValue = 0.000579; mean CPM = 618.7; activating transcription factor 4 (tax-responsive enhancer element B67)" ID="ID_999042375" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKX: 1.31-fold Down; FDR = 0.00331; PValue = 0.000658; mean CPM = 24.94; protein kinase, X-linked" ID="ID_536593307" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DUSP10: 1.56-fold Down; FDR = 0.00343; PValue = 0.000687; mean CPM = 9.531; dual specificity phosphatase 10" ID="ID_433142860" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1B: 1.43-fold Up; FDR = 0.00346; PValue = 0.000693; mean CPM = 12.81; RAP1B, member of RAS oncogene family" ID="ID_1200842019" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNA2D4: 1.71-fold Up; FDR = 0.00375; PValue = 0.000764; mean CPM = 4.238; calcium channel, voltage-dependent, alpha 2/delta subunit 4" ID="ID_457316698" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG12: 1.31-fold Up; FDR = 0.00387; PValue = 0.000792; mean CPM = 24.97; guanine nucleotide binding protein (G protein), gamma 12" ID="ID_778617288" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAX: 1.28-fold Up; FDR = 0.00569; PValue = 0.00123; mean CPM = 29.78; MYC associated factor X" ID="ID_1172013874" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_1022024797" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K14: 1.47-fold Down; FDR = 0.00704; PValue = 0.00157; mean CPM = 9.470; mitogen-activated protein kinase kinase kinase 14" ID="ID_1791205834" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF12: 1.26-fold Up; FDR = 0.00782; PValue = 0.00177; mean CPM = 34.71; fibroblast growth factor 12" ID="ID_936518854" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K3: 1.26-fold Down; FDR = 0.00786; PValue = 0.00178; mean CPM = 38.85; mitogen-activated protein kinase kinase kinase 3" ID="ID_1423214912" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GADD45B: 1.49-fold Down; FDR = 0.0082; PValue = 0.00187; mean CPM = 175.6; growth arrest and DNA-damage-inducible, beta" ID="ID_1859096683" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DUSP3: 1.27-fold Down; FDR = 0.0115; PValue = 0.00274; mean CPM = 24.56; dual specificity phosphatase 3" ID="ID_1445222916" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K11: 1.24-fold Down; FDR = 0.0116; PValue = 0.00279; mean CPM = 45.82; mitogen-activated protein kinase kinase kinase 11" ID="ID_1168846496" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFB: 1.97-fold Down; FDR = 0.0133; PValue = 0.00326; mean CPM = 2.424; platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)" ID="ID_1121789980" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BDNF: 1.23-fold Down; FDR = 0.0158; PValue = 0.00399; mean CPM = 104.4; Brain-derived neurotrophic factor" ID="ID_382409039" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GADD45G: 1.49-fold Up; FDR = 0.0173; PValue = 0.00444; mean CPM = 12.01; growth arrest and DNA-damage-inducible, gamma" ID="ID_1329982305" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NTF3: 1.32-fold Down; FDR = 0.0174; PValue = 0.00448; mean CPM = 12.78; Neurotrophin-3; Uncharacterized protein" ID="ID_1117923891" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN5: 3.05-fold Down; FDR = 0.0177; PValue = 0.00455; mean CPM = 1.043; protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)" ID="ID_1101398911" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_225303865" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA6: 2.05-fold Down; FDR = 0.0226; PValue = 0.00604; mean CPM = 2.573; heat shock 70kDa protein 6 (HSP70B')" ID="ID_1972129685" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA1: 1.25-fold Down; FDR = 0.0241; PValue = 0.00652; mean CPM = 21.28; ribosomal protein S6 kinase, 90kDa, polypeptide 1" ID="ID_1571150568" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_744636753" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF21: 1.97-fold Up; FDR = 0.0263; PValue = 0.00722; mean CPM = 56.49; fibroblast growth factor 21" ID="ID_288082299" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RRAS2: 1.21-fold Up; FDR = 0.0278; PValue = 0.00771; mean CPM = 61.00; related RAS viral (r-ras) oncogene homolog 2" ID="ID_1655014358" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_1289400061" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC2: 2.96-fold Up; FDR = 0.0309; PValue = 0.00872; mean CPM = 0.9737; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)" ID="ID_1266565400" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNA1F: 2.4-fold Down; FDR = 0.0315; PValue = 0.00892; mean CPM = 1.129; calcium channel, voltage-dependent, L type, alpha 1F subunit" ID="ID_1936824734" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GADD45A: 1.22-fold Up; FDR = 0.0344; PValue = 0.00989; mean CPM = 127.8; growth arrest and DNA-damage-inducible, alpha" ID="ID_797609760" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ECSIT: 1.2-fold Down; FDR = 0.0358; PValue = 0.0104; mean CPM = 54.27; ECSIT homolog (Drosophila)" ID="ID_1225580234" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFBR1: 1.2-fold Up; FDR = 0.037; PValue = 0.0108; mean CPM = 90.92; transforming growth factor, beta receptor 1" ID="ID_1256995027" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_928977132" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KRAS: 1.35-fold Down; FDR = 0.0401; PValue = 0.0119; mean CPM = 13.10; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog" ID="ID_515213384" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNA1D: 2.26-fold Down; FDR = 0.0434; PValue = 0.013; mean CPM = 1.171; calcium channel, voltage-dependent, L type, alpha 1D subunit" ID="ID_1363453667" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NRAS: 1.2-fold Down; FDR = 0.0546; PValue = 0.017; mean CPM = 32.39; neuroblastoma RAS viral (v-ras) oncogene homolog" ID="ID_162618115" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPRR: 1.72-fold Down; FDR = 0.0559; PValue = 0.0175; mean CPM = 7.682; protein tyrosine phosphatase, receptor type, R" ID="ID_997146619" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DUSP16: 1.22-fold Up; FDR = 0.0568; PValue = 0.0179; mean CPM = 20.15; dual specificity phosphatase 16" ID="ID_1122188773" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELB: 1.22-fold Down; FDR = 0.0606; PValue = 0.0193; mean CPM = 26.64; v-rel reticuloendotheliosis viral oncogene homolog B" ID="ID_1382161415" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000005123: 1.25-fold Down; FDR = 0.0639; PValue = 0.0206; mean CPM = 15.11; Uncharacterized protein" ID="ID_1388027370" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFBR2: 1.19-fold Up; FDR = 0.0643; PValue = 0.0208; mean CPM = 350.8; transforming growth factor, beta receptor II (70/80kDa)" ID="ID_1059957151" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_360417859" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPKAPK3: 1.18-fold Up; FDR = 0.0689; PValue = 0.0225; mean CPM = 35.42; mitogen-activated protein kinase-activated protein kinase 3" ID="ID_116512940" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_628304132" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MKNK1: 1.27-fold Down; FDR = 0.0706; PValue = 0.0232; mean CPM = 9.169; MAP kinase interacting serine/threonine kinase 1" ID="ID_1316922068" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K8: 1.35-fold Down; FDR = 0.0831; PValue = 0.0281; mean CPM = 8.912; mitogen-activated protein kinase kinase kinase 8" ID="ID_1040610804" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF11: 1.44-fold Down; FDR = 0.0841; PValue = 0.0285; mean CPM = 3.869; fibroblast growth factor 11" ID="ID_1220171222" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNA2D3: 1.74-fold Down; FDR = 0.0883; PValue = 0.0302; mean CPM = 6.008; calcium channel, voltage-dependent, alpha 2/delta subunit 3" ID="ID_537432513" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1A: 1.17-fold Up; FDR = 0.0888; PValue = 0.0304; mean CPM = 37.16; RAP1A, member of RAS oncogene family" ID="ID_1134399285" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS2: 1.17-fold Up; FDR = 0.1; PValue = 0.0353; mean CPM = 31.79; son of sevenless homolog 2 (Drosophila)" ID="ID_860194535" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARRB1: 1.35-fold Down; FDR = 0.107; PValue = 0.0382; mean CPM = 4.106; arrestin, beta 1" ID="ID_493555168" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MECOM: 1.24-fold Up; FDR = 0.115; PValue = 0.0416; mean CPM = 20.27; Uncharacterized protein" ID="ID_956473561" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_1355870180" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MKNK2: 1.23-fold Up; FDR = 0.123; PValue = 0.0449; mean CPM = 81.36; MAP kinase interacting serine/threonine kinase 2" ID="ID_364047201" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_698024732" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DUSP6: 1.22-fold Up; FDR = 0.131; PValue = 0.0487; mean CPM = 91.01; dual specificity phosphatase 6" ID="ID_721331053" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK2: 1.15-fold Up; FDR = 0.134; PValue = 0.0502; mean CPM = 89.49; p21 protein (Cdc42/Rac)-activated kinase 2" ID="ID_1725719438" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGFR1: 1.15-fold Down; FDR = 0.139; PValue = 0.0525; mean CPM = 89.41; fibroblast growth factor receptor 1" ID="ID_876883564" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_734803359" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNB1: 1.31-fold Down; FDR = 0.157; PValue = 0.0608; mean CPM = 5.053; calcium channel, voltage-dependent, beta 1 subunit" ID="ID_1123160863" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF23: 2.01-fold Down; FDR = 0.188; PValue = 0.0759; mean CPM = 0.9718; fibroblast growth factor 23" ID="ID_241618547" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_356278695" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DUSP4: 1.28-fold Down; FDR = 0.199; PValue = 0.0817; mean CPM = 66.70; dual specificity phosphatase 4" ID="ID_1969252877" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASGRP1: 1.4-fold Down; FDR = 0.224; PValue = 0.0945; mean CPM = 2.348; RAS guanyl releasing protein 1 (calcium and DAG-regulated)" ID="ID_15527838" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BRAF: 1.14-fold Down; FDR = 0.228; PValue = 0.0964; mean CPM = 24.98; v-raf murine sarcoma viral oncogene homolog B1" ID="ID_865107751" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF10: 1.55-fold Down; FDR = 0.257; PValue = 0.112; mean CPM = 3.488; fibroblast growth factor 10" ID="ID_385346002" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_1309485614" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K4: 1.13-fold Down; FDR = 0.284; PValue = 0.126; mean CPM = 25.34; Uncharacterized protein" ID="ID_949923894" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA4: 1.12-fold Down; FDR = 0.296; PValue = 0.133; mean CPM = 39.50; ribosomal protein S6 kinase, 90kDa, polypeptide 4" ID="ID_973601695" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPKAPK5: 1.15-fold Down; FDR = 0.297; PValue = 0.134; mean CPM = 13.06; mitogen-activated protein kinase-activated protein kinase 5" ID="ID_1466392924" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1A: 1.11-fold Up; FDR = 0.297; PValue = 0.134; mean CPM = 134.7; tumor necrosis factor receptor superfamily, member 1A" ID="ID_1030727215" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1A: 1.5-fold Up; FDR = 0.315; PValue = 0.144; mean CPM = 155.4; interleukin 1, alpha" ID="ID_670742716" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLA2G4F: 1.77-fold Down; FDR = 0.336; PValue = 0.156; mean CPM = 0.9440; phospholipase A2, group IVF" ID="ID_713921805" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP1: 1.12-fold Down; FDR = 0.351; PValue = 0.165; mean CPM = 17.96; TGF-beta activated kinase 1/MAP3K7 binding protein 1" ID="ID_1448441343" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MEF2C: 1.24-fold Down; FDR = 0.357; PValue = 0.168; mean CPM = 6.816; myocyte enhancer factor 2C" ID="ID_552040277" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP53: 1.11-fold Down; FDR = 0.364; PValue = 0.172; mean CPM = 33.25; tumor protein p53" ID="ID_65196150" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRKL: 1.11-fold Up; FDR = 0.371; PValue = 0.176; mean CPM = 34.10; v-crk sarcoma virus CT10 oncogene homolog (avian)-like" ID="ID_1750487682" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NF1: 1.1-fold Up; FDR = 0.383; PValue = 0.184; mean CPM = 199.1; neurofibromin 1" ID="ID_1955641796" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_1682378481" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RRAS: 1.1-fold Up; FDR = 0.415; PValue = 0.203; mean CPM = 223.0; related RAS viral (r-ras) oncogene homolog" ID="ID_708133221" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1280046420" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK12: 1.19-fold Down; FDR = 0.422; PValue = 0.208; mean CPM = 6.569; mitogen-activated protein kinase 12" ID="ID_262426251" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1718870666" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC1: 1.11-fold Down; FDR = 0.457; PValue = 0.23; mean CPM = 19.06; Uncharacterized protein" ID="ID_577236956" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNB3: 1.1-fold Down; FDR = 0.459; PValue = 0.231; mean CPM = 26.21; calcium channel, voltage-dependent, beta 3 subunit" ID="ID_1571945865" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP3CB: 1.08-fold Up; FDR = 0.514; PValue = 0.268; mean CPM = 76.44; protein phosphatase 3, catalytic subunit, beta isozyme" ID="ID_1963113737" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK13: 1.22-fold Down; FDR = 0.536; PValue = 0.284; mean CPM = 3.100; mitogen-activated protein kinase 13" ID="ID_990478393" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8IP2: 1.29-fold Down; FDR = 0.543; PValue = 0.289; mean CPM = 2.167; mitogen-activated protein kinase 8 interacting protein 2" ID="ID_1481280508" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF18: 1.55-fold Down; FDR = 0.548; PValue = 0.293; mean CPM = 0.9359; fibroblast growth factor 18" ID="ID_1488824424" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNA2D1: 1.13-fold Down; FDR = 0.562; PValue = 0.303; mean CPM = 10.13; calcium channel, voltage-dependent, alpha 2/delta subunit 1" ID="ID_34260809" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNA1I: 1.48-fold Down; FDR = 0.57; PValue = 0.309; mean CPM = 0.9895; Uncharacterized protein" ID="ID_1347966041" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNB2: 1.4-fold Down; FDR = 0.573; PValue = 0.31; mean CPM = 1.119; calcium channel, voltage-dependent, beta 2 subunit" ID="ID_1063285159" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K5: 1.21-fold Down; FDR = 0.6; PValue = 0.33; mean CPM = 8.023; mitogen-activated protein kinase kinase kinase 5" ID="ID_189277617" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDC42: 1.07-fold Down; FDR = 0.608; PValue = 0.335; mean CPM = 91.67; cell division cycle 42" ID="ID_1154417872" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCG: 1.47-fold Down; FDR = 0.609; PValue = 0.336; mean CPM = 0.9297; protein kinase C, gamma" ID="ID_328626589" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1R2: 1.37-fold Up; FDR = 0.628; PValue = 0.35; mean CPM = 1.132; interleukin 1 receptor, type II" ID="ID_1680242335" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF5: 1.1-fold Down; FDR = 0.646; PValue = 0.364; mean CPM = 54.02; fibroblast growth factor 5" ID="ID_1004787717" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_1486803974" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STMN1: 1.15-fold Down; FDR = 0.684; PValue = 0.395; mean CPM = 43.13; Stathmin" ID="ID_1218364346" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCB: 1.86-fold Up; FDR = 0.727; PValue = 0.43; mean CPM = 0.8705; protein kinase C, beta" ID="ID_1126048691" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPKAPK2: 1.06-fold Down; FDR = 0.733; PValue = 0.435; mean CPM = 82.16; mitogen-activated protein kinase-activated protein kinase 2" ID="ID_1850580409" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNA1H: 1.38-fold Down; FDR = 0.735; PValue = 0.437; mean CPM = 0.9035; calcium channel, voltage-dependent, T type, alpha 1H subunit" ID="ID_1746085611" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF9: 1.77-fold Up; FDR = 0.74; PValue = 0.441; mean CPM = 0.8485; fibroblast growth factor 9 (glia-activating factor)" ID="ID_782013475" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNG1: 1.82-fold Up; FDR = 0.74; PValue = 0.442; mean CPM = 0.8669; calcium channel, voltage-dependent, gamma subunit 1" ID="ID_855412598" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_865589658" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF8: 1.75-fold Down; FDR = 0.783; PValue = 0.48; mean CPM = 0.8245; Uncharacterized protein" ID="ID_179290984" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZAK: 1.05-fold Down; FDR = 0.789; PValue = 0.486; mean CPM = 32.04; Mitogen-activated protein kinase kinase kinase MLT isoform 2; Uncharacterized protein" ID="ID_1303032299" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRK: 1.05-fold Up; FDR = 0.791; PValue = 0.488; mean CPM = 59.92; v-crk sarcoma virus CT10 oncogene homolog (avian)" ID="ID_925945425" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACG: 1.51-fold Down; FDR = 0.795; PValue = 0.491; mean CPM = 0.8026; protein kinase, cAMP-dependent, catalytic, gamma" ID="ID_1091188740" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF14: 1.13-fold Down; FDR = 0.809; PValue = 0.505; mean CPM = 6.007; fibroblast growth factor 14" ID="ID_202327413" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DUSP9: 1.24-fold Down; FDR = 0.82; PValue = 0.518; mean CPM = 1.376; dual specificity phosphatase 9" ID="ID_1871644875" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNA1S: 1.33-fold Down; FDR = 0.823; PValue = 0.522; mean CPM = 0.8938; calcium channel, voltage-dependent, L type, alpha 1S subunit" ID="ID_990907874" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP5C: 1.05-fold Up; FDR = 0.826; PValue = 0.526; mean CPM = 49.97; protein phosphatase 5, catalytic subunit" ID="ID_774447679" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLA2G4A: 1.08-fold Down; FDR = 0.836; PValue = 0.541; mean CPM = 40.53; phospholipase A2, group IVA (cytosolic, calcium-dependent)" ID="ID_572585589" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNG7: 1.29-fold Down; FDR = 0.836; PValue = 0.541; mean CPM = 0.8254; calcium channel, voltage-dependent, gamma subunit 7" ID="ID_1265901390" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN7: 1.29-fold Up; FDR = 0.851; PValue = 0.562; mean CPM = 0.8740; protein tyrosine phosphatase, non-receptor type 7" ID="ID_795558030" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_386883320" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1981998451" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP4K1: 1.26-fold Up; FDR = 0.879; PValue = 0.598; mean CPM = 0.9281; mitogen-activated protein kinase kinase kinase kinase 1" ID="ID_1422498905" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF13: 1.24-fold Up; FDR = 0.882; PValue = 0.602; mean CPM = 1.024; Fibroblast growth factor 13 isoform 1; Uncharacterized protein" ID="ID_452264525" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_1449581220" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK7: 1.04-fold Down; FDR = 0.899; PValue = 0.632; mean CPM = 16.93; Uncharacterized protein" ID="ID_661072230" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF3: 1.22-fold Down; FDR = 0.903; PValue = 0.641; mean CPM = 0.7938; fibroblast growth factor 3 (murine mammary tumor virus integration site (v-int-2) oncogene homolog)" ID="ID_781067578" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASGRF1: 1.14-fold Down; FDR = 0.903; PValue = 0.648; mean CPM = 1.594; Ras protein-specific guanine nucleotide-releasing factor 1" ID="ID_1435474628" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB2: 1.05-fold Down; FDR = 0.903; PValue = 0.655; mean CPM = 110.8; transforming growth factor, beta 2" ID="ID_508674060" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF17: 1.34-fold Down; FDR = 0.903; PValue = 0.662; mean CPM = 0.8230; fibroblast growth factor 17" ID="ID_551405950" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000021684: 1.44-fold Up; FDR = 0.903; PValue = 0.662; mean CPM = 0.8513; Uncharacterized protein" ID="ID_311900619" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNG3: 1.17-fold Up; FDR = 0.908; PValue = 0.683; mean CPM = 0.7891; calcium channel, voltage-dependent, gamma subunit 3" ID="ID_806386672" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASA1: 1.03-fold Down; FDR = 0.909; PValue = 0.69; mean CPM = 103.7; Ras GTPase-activating protein 1 isoform 1; Uncharacterized protein" ID="ID_302797365" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACB: 1.03-fold Up; FDR = 0.911; PValue = 0.694; mean CPM = 30.10; protein kinase, cAMP-dependent, catalytic, beta" ID="ID_399716463" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NTF4: 1.14-fold Up; FDR = 0.911; PValue = 0.701; mean CPM = 0.7902; neurotrophin 4" ID="ID_212939822" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK1: 1.03-fold Down; FDR = 0.911; PValue = 0.705; mean CPM = 18.65; p21 protein (Cdc42/Rac)-activated kinase 1" ID="ID_618215396" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF19: 1.33-fold Down; FDR = 0.921; PValue = 0.724; mean CPM = 0.8101; fibroblast growth factor 19" ID="ID_370489919" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K2: 1.03-fold Up; FDR = 0.924; PValue = 0.73; mean CPM = 40.64; mitogen-activated protein kinase kinase kinase 2" ID="ID_1976816913" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP4K3: 1.03-fold Down; FDR = 0.926; PValue = 0.732; mean CPM = 18.57; mitogen-activated protein kinase kinase kinase kinase 3" ID="ID_1420195872" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB1: 1.02-fold Down; FDR = 0.936; PValue = 0.749; mean CPM = 62.61; transforming growth factor, beta 1" ID="ID_1276883019" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FASLG: 1.2-fold Down; FDR = 0.941; PValue = 0.757; mean CPM = 0.8088; Fas ligand (TNF superfamily, member 6)" ID="ID_928415371" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA6: 1.05-fold Down; FDR = 0.941; PValue = 0.758; mean CPM = 3.315; ribosomal protein S6 kinase, 90kDa, polypeptide 6" ID="ID_879011236" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_1743460941" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF6: 1.15-fold Up; FDR = 0.948; PValue = 0.773; mean CPM = 0.8082; fibroblast growth factor 6" ID="ID_1709762196" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NTRK2: 1.06-fold Down; FDR = 0.95; PValue = 0.775; mean CPM = 3.967; neurotrophic tyrosine kinase, receptor, type 2" ID="ID_211358720" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC3: 1.03-fold Down; FDR = 0.952; PValue = 0.78; mean CPM = 13.31; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3" ID="ID_1274568789" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MOS: 1.02-fold Up; FDR = 0.958; PValue = 0.791; mean CPM = 0.8131; v-mos Moloney murine sarcoma viral oncogene homolog" ID="ID_158358443" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K13: 1.03-fold Up; FDR = 0.962; PValue = 0.796; mean CPM = 6.973; mitogen-activated protein kinase kinase kinase 13" ID="ID_185032010" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_1892940280" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_1114288607" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NTRK1: 1.07-fold Up; FDR = 0.977; PValue = 0.82; mean CPM = 1.195; neurotrophic tyrosine kinase, receptor, type 1" ID="ID_1122910323" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA3: 1.02-fold Up; FDR = 0.982; PValue = 0.829; mean CPM = 58.16; ribosomal protein S6 kinase, 90kDa, polypeptide 3" ID="ID_1365572737" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNA1G: 1.06-fold Down; FDR = 0.991; PValue = 0.844; mean CPM = 1.671; Uncharacterized protein" ID="ID_1342237387" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_1667456078" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFRB: 1.01-fold Up; FDR = 1; PValue = 0.883; mean CPM = 391.1; platelet-derived growth factor receptor, beta polypeptide" ID="ID_1925536957" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGF: 1.06-fold Down; FDR = 1; PValue = 0.885; mean CPM = 0.8917; epidermal growth factor" ID="ID_1023773548" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNG2: 1.05-fold Up; FDR = 1; PValue = 0.915; mean CPM = 0.9147; calcium channel, voltage-dependent, gamma subunit 2" ID="ID_746015478" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLA2G4D: 1.01-fold Up; FDR = 1; PValue = 0.97; mean CPM = 0.9806; phospholipase A2, group IVD (cytosolic)" ID="ID_564512735" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLK: No Change; FDR = 1; PValue = 0.97; mean CPM = 11.78; nemo-like kinase" ID="ID_1130533048" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DAXX: No Change; FDR = 1; PValue = 0.984; mean CPM = 106.5; Death domain-associated protein 6 (Daxx)(hDaxx)(Fas death domain-associated protein)(ETS1-associated protein 1)(EAP1)" ID="ID_34468108" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNG4: 1.03-fold Up; FDR = 1; PValue = 0.993; mean CPM = 0.8322; calcium channel, voltage-dependent, gamma subunit 4" ID="ID_1508810983" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF20: No Change; FDR = 1; PValue = 1; mean CPM = 0.7796; fibroblast growth factor 20" ID="ID_150306820" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNG6: No Change; FDR = 1; PValue = 1; mean CPM = 0.7800; calcium channel, voltage-dependent, gamma subunit 6" ID="ID_1806700163" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Jak-STAT signaling pathway: Activated, FDR = 0.0251, FWER = 0.628, PValue = 0.00433" ID="ID_1897762307" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="IRF9: 3.85-fold Up; FDR = 2.6e-19; PValue = 1.12e-21; mean CPM = 106.4; interferon regulatory factor 9" ID="ID_1339326311" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT2: 2.67-fold Up; FDR = 8.02e-19; PValue = 4.03e-21; mean CPM = 185.6; signal transducer and activator of transcription 2, 113kDa" ID="ID_50216580" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_1060807594" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1604985223" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL15RA: 19.4-fold Up; FDR = 4.04e-17; PValue = 2.89e-19; mean CPM = 5.291; interleukin 15 receptor, alpha" ID="ID_322333860" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5A: 2.28-fold Up; FDR = 6.87e-14; PValue = 8.58e-16; mean CPM = 21.55; signal transducer and activator of transcription 5A" ID="ID_1052133054" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPRY1: 3.01-fold Up; FDR = 7.75e-14; PValue = 9.87e-16; mean CPM = 27.88; sprouty homolog 1, antagonist of FGF signaling (Drosophila)" ID="ID_1843912768" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_128437105" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND3: 2.27-fold Down; FDR = 8.38e-11; PValue = 2.15e-12; mean CPM = 86.90; cyclin D3" ID="ID_1740566490" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIAS3: 1.63-fold Down; FDR = 2.24e-10; PValue = 6.51e-12; mean CPM = 53.00; protein inhibitor of activated STAT, 3" ID="ID_1796993805" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPRY4: 2.68-fold Down; FDR = 2.32e-10; PValue = 6.78e-12; mean CPM = 12.79; sprouty homolog 4 (Drosophila)" ID="ID_638145941" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL13RA1: 1.73-fold Up; FDR = 1.81e-09; PValue = 6.5e-11; mean CPM = 42.50; interleukin 13 receptor, alpha 1" ID="ID_1938677109" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_1473089438" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL6ST: 1.78-fold Up; FDR = 1.86e-08; PValue = 8.65e-10; mean CPM = 437.6; interleukin 6 signal transducer (gp130, oncostatin M receptor)" ID="ID_1343977031" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL11RA: 1.66-fold Down; FDR = 1.74e-07; PValue = 1.02e-08; mean CPM = 33.61; interleukin 11 receptor, alpha" ID="ID_971163284" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_652365164" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L1: 1.51-fold Up; FDR = 9.13e-07; PValue = 6.52e-08; mean CPM = 66.15; Bcl-2-like protein 1; Bcl-2-like protein 1 isoform 1; Uncharacterized protein" ID="ID_1076112071" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1761080160" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_251446204" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR2: 1.74-fold Up; FDR = 1.85e-06; PValue = 1.44e-07; mean CPM = 26.05; interferon (alpha, beta and omega) receptor 2" ID="ID_1392556750" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_48442668" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="OSMR: 1.49-fold Up; FDR = 1.63e-05; PValue = 1.62e-06; mean CPM = 180.8; Uncharacterized protein" ID="ID_796576953" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT4: 1.79-fold Up; FDR = 2.3e-05; PValue = 2.36e-06; mean CPM = 26.79; signal transducer and activator of transcription 4" ID="ID_552540475" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS5: 1.38-fold Up; FDR = 4.45e-05; PValue = 4.96e-06; mean CPM = 88.27; suppressor of cytokine signaling 5" ID="ID_799082447" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL20RB: 3.26-fold Up; FDR = 6.13e-05; PValue = 7.16e-06; mean CPM = 4.526; interleukin 20 receptor beta" ID="ID_1923166274" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL6R: 3.84-fold Down; FDR = 6.68e-05; PValue = 7.89e-06; mean CPM = 4.840; interleukin 6 receptor" ID="ID_1136898462" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LIFR: 1.59-fold Up; FDR = 0.000539; PValue = 8.35e-05; mean CPM = 35.74; leukemia inhibitory factor receptor alpha" ID="ID_853619256" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS3: 1.69-fold Up; FDR = 0.000994; PValue = 0.000167; mean CPM = 37.76; suppressor of cytokine signaling 3" ID="ID_564067748" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CISH: 1.95-fold Up; FDR = 0.00116; PValue = 0.0002; mean CPM = 5.083; cytokine inducible SH2-containing protein" ID="ID_558463228" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR1: 1.31-fold Up; FDR = 0.00151; PValue = 0.000268; mean CPM = 37.77; interferon gamma receptor 1" ID="ID_1320979905" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAM2: 1.3-fold Up; FDR = 0.00163; PValue = 0.000295; mean CPM = 50.32; signal transducing adaptor molecule (SH3 domain and ITAM motif) 2" ID="ID_330125303" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK3: 2.31-fold Up; FDR = 0.00186; PValue = 0.000342; mean CPM = 2.154; Janus kinase 3" ID="ID_1961747198" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIAS1: 1.3-fold Up; FDR = 0.00259; PValue = 0.000498; mean CPM = 29.99; protein inhibitor of activated STAT, 1" ID="ID_143472538" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CBLC: 2.87-fold Down; FDR = 0.00443; PValue = 0.000923; mean CPM = 3.105; Cas-Br-M (murine) ecotropic retroviral transforming sequence c" ID="ID_71456308" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR1: 1.27-fold Up; FDR = 0.0101; PValue = 0.00237; mean CPM = 82.39; Uncharacterized protein" ID="ID_1661436750" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EPOR: 1.56-fold Down; FDR = 0.014; PValue = 0.00347; mean CPM = 3.898; erythropoietin receptor" ID="ID_652649880" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYK2: 1.24-fold Down; FDR = 0.0142; PValue = 0.00354; mean CPM = 42.58; tyrosine kinase 2" ID="ID_176321670" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS2: 1.31-fold Down; FDR = 0.0188; PValue = 0.0049; mean CPM = 35.29; suppressor of cytokine signaling 2" ID="ID_1444124123" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRLF2: 2.92-fold Down; FDR = 0.0202; PValue = 0.00531; mean CPM = 1.758; cytokine receptor-like factor 2" ID="ID_1207834314" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL20RA: 2.25-fold Up; FDR = 0.0255; PValue = 0.00695; mean CPM = 1.386; interleukin 20 receptor, alpha" ID="ID_1256128523" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_300807858" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR2: 1.23-fold Up; FDR = 0.0258; PValue = 0.00707; mean CPM = 46.52; interferon gamma receptor 2 (interferon gamma transducer 1)" ID="ID_1989906735" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIM1: 1.39-fold Down; FDR = 0.0325; PValue = 0.00926; mean CPM = 21.11; pim-1 oncogene" ID="ID_1594417373" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIAS4: 1.22-fold Down; FDR = 0.0547; PValue = 0.0171; mean CPM = 18.45; protein inhibitor of activated STAT, 4" ID="ID_1285580056" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_1250029086" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL7R: 1.76-fold Down; FDR = 0.0698; PValue = 0.0229; mean CPM = 3.067; interleukin 7 receptor" ID="ID_78228366" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT6: 1.18-fold Up; FDR = 0.0727; PValue = 0.024; mean CPM = 217.5; signal transducer and activator of transcription 6, interleukin-4 induced" ID="ID_388384562" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL13RA2: 2.13-fold Up; FDR = 0.0909; PValue = 0.0313; mean CPM = 1.485; Interleukin-13 receptor subunit alpha-2; Uncharacterized protein" ID="ID_1381373332" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_1520796789" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS2: 1.17-fold Up; FDR = 0.1; PValue = 0.0353; mean CPM = 31.79; son of sevenless homolog 2 (Drosophila)" ID="ID_1119062076" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL28RA: 2.43-fold Down; FDR = 0.115; PValue = 0.0414; mean CPM = 0.9001; interleukin 28 receptor, alpha (interferon, lambda receptor)" ID="ID_1427891489" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND1: 1.17-fold Up; FDR = 0.121; PValue = 0.0443; mean CPM = 867.3; cyclin D1" ID="ID_565603057" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPRED1: 1.15-fold Up; FDR = 0.143; PValue = 0.0543; mean CPM = 41.74; sprouty-related, EVH1 domain containing 1" ID="ID_1916376535" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_762183930" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_1646126910" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12RB2: 1.42-fold Down; FDR = 0.299; PValue = 0.135; mean CPM = 1.728; interleukin 12 receptor, beta 2" ID="ID_539099237" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EP300: 1.11-fold Up; FDR = 0.312; PValue = 0.142; mean CPM = 162.8; E1A binding protein p300" ID="ID_898692018" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_938519617" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND2: 1.2-fold Up; FDR = 0.335; PValue = 0.155; mean CPM = 76.91; cyclin D2" ID="ID_93762505" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GHR: 1.23-fold Up; FDR = 0.369; PValue = 0.175; mean CPM = 6.312; growth hormone receptor" ID="ID_14241051" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1874749903" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MPL: 1.3-fold Down; FDR = 0.411; PValue = 0.201; mean CPM = 2.108; myeloproliferative leukemia virus oncogene" ID="ID_527015599" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CNTFR: 1.67-fold Down; FDR = 0.435; PValue = 0.216; mean CPM = 1.033; Uncharacterized protein" ID="ID_67317079" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_262153887" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPRED3: 1.17-fold Down; FDR = 0.471; PValue = 0.239; mean CPM = 4.899; sprouty-related, EVH1 domain containing 3" ID="ID_1139016063" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LEPR: 1.52-fold Down; FDR = 0.489; PValue = 0.251; mean CPM = 1.051; leptin receptor" ID="ID_582675984" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPRY2: 1.09-fold Down; FDR = 0.515; PValue = 0.269; mean CPM = 27.90; sprouty homolog 2 (Drosophila)" ID="ID_1420322380" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL10RA: 1.55-fold Down; FDR = 0.516; PValue = 0.269; mean CPM = 0.9545; interleukin 10 receptor, alpha" ID="ID_1092865287" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_1407235800" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL21R: 1.56-fold Down; FDR = 0.534; PValue = 0.282; mean CPM = 1.021; interleukin 21 receptor" ID="ID_266261330" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL9R: 2.21-fold Down; FDR = 0.63; PValue = 0.352; mean CPM = 0.8661; interleukin 9 receptor" ID="ID_1164497590" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12RB1: 1.39-fold Up; FDR = 0.703; PValue = 0.41; mean CPM = 0.9665; interleukin 12 receptor, beta 1" ID="ID_1711451759" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL4R: 1.05-fold Down; FDR = 0.803; PValue = 0.499; mean CPM = 193.5; interleukin 4 receptor" ID="ID_159078799" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIAS2: 1.06-fold Down; FDR = 0.807; PValue = 0.503; mean CPM = 19.53; protein inhibitor of activated STAT, 2" ID="ID_1461405667" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CBL: 1.05-fold Down; FDR = 0.824; PValue = 0.524; mean CPM = 51.06; Cas-Br-M (murine) ecotropic retroviral transforming sequence" ID="ID_1984048428" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL22RA1: 1.26-fold Up; FDR = 0.846; PValue = 0.555; mean CPM = 0.9674; interleukin 22 receptor, alpha 1" ID="ID_1385954207" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS7: 1.07-fold Down; FDR = 0.847; PValue = 0.556; mean CPM = 7.514; suppressor of cytokine signaling 7" ID="ID_831959317" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CBLB: 1.04-fold Down; FDR = 0.859; PValue = 0.574; mean CPM = 64.59; Cas-Br-M (murine) ecotropic retroviral transforming sequence b" ID="ID_1479419843" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAM: 1.04-fold Down; FDR = 0.899; PValue = 0.627; mean CPM = 29.84; signal transducing adaptor molecule (SH3 domain and ITAM motif) 1" ID="ID_1604765127" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL22RA2: 1.2-fold Down; FDR = 0.899; PValue = 0.629; mean CPM = 0.7954; interleukin 22 receptor, alpha 2" ID="ID_985348006" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSF2RA: 1.19-fold Up; FDR = 0.906; PValue = 0.666; mean CPM = 0.9897; colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)" ID="ID_748575381" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSF3R: 1.13-fold Down; FDR = 0.921; PValue = 0.723; mean CPM = 0.9331; colony stimulating factor 3 receptor (granulocyte)" ID="ID_133579513" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS4: 1.03-fold Up; FDR = 0.921; PValue = 0.724; mean CPM = 17.28; suppressor of cytokine signaling 4" ID="ID_788778474" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2RA: 1.08-fold Up; FDR = 0.945; PValue = 0.766; mean CPM = 0.8493; interleukin 2 receptor, alpha" ID="ID_1059063123" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL5RA: 1.1-fold Up; FDR = 0.958; PValue = 0.791; mean CPM = 0.8108; interleukin 5 receptor, alpha" ID="ID_542465780" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREBBP: 1.01-fold Down; FDR = 0.993; PValue = 0.847; mean CPM = 137.7; CREB binding protein" ID="ID_1065707085" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRLR: 1.06-fold Down; FDR = 1; PValue = 0.889; mean CPM = 1.017; prolactin receptor" ID="ID_1109077655" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL23R: 1.05-fold Down; FDR = 1; PValue = 0.994; mean CPM = 0.7958; interleukin 23 receptor" ID="ID_1268888016" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Basal cell carcinoma: Inhibited, FDR = 0.0274, FWER = 0.725, PValue = 0.005" ID="ID_1394687012" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="FZD2: 2.27-fold Down; FDR = 5e-11; PValue = 1.24e-12; mean CPM = 20.66; frizzled homolog 2 (Drosophila)" ID="ID_1970787729" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD7: 1.62-fold Down; FDR = 5.66e-06; PValue = 4.95e-07; mean CPM = 34.19; frizzled homolog 7 (Drosophila)" ID="ID_137346605" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GLI2: 2.04-fold Down; FDR = 8.71e-06; PValue = 8.1e-07; mean CPM = 14.39; GLI family zinc finger 2" ID="ID_211866461" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT5A: 1.65-fold Down; FDR = 2.5e-05; PValue = 2.59e-06; mean CPM = 136.4; wingless-type MMTV integration site family, member 5A" ID="ID_1014360511" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000009315: 1.44-fold Down; FDR = 4.44e-05; PValue = 4.94e-06; mean CPM = 22.79" ID="ID_1078833757" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD9: 2.74-fold Down; FDR = 0.000408; PValue = 6.1e-05; mean CPM = 1.789; frizzled homolog 9 (Drosophila)" ID="ID_425974016" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTCH2: 2.16-fold Down; FDR = 0.000581; PValue = 9.08e-05; mean CPM = 4.080; Uncharacterized protein" ID="ID_1196287477" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT1: 7.1-fold Down; FDR = 0.000659; PValue = 0.000105; mean CPM = 2.664; wingless-type MMTV integration site family, member 1" ID="ID_1791120343" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DVL3: 1.29-fold Down; FDR = 0.00157; PValue = 0.00028; mean CPM = 67.95; dishevelled, dsh homolog 3 (Drosophila)" ID="ID_1949458977" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD4: 1.83-fold Up; FDR = 0.00258; PValue = 0.000495; mean CPM = 4.537; frizzled homolog 4 (Drosophila)" ID="ID_686864355" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT7A: 3.46-fold Down; FDR = 0.00638; PValue = 0.0014; mean CPM = 1.036; wingless-type MMTV integration site family, member 7A" ID="ID_120228669" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT10A: 4.08-fold Down; FDR = 0.00805; PValue = 0.00183; mean CPM = 0.9138; wingless-type MMTV integration site family, member 10A" ID="ID_628017322" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BMP2: 2.5-fold Up; FDR = 0.00836; PValue = 0.00191; mean CPM = 3.220; bone morphogenetic protein 2" ID="ID_643719759" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT5B: 1.58-fold Down; FDR = 0.00866; PValue = 0.002; mean CPM = 7.832; wingless-type MMTV integration site family, member 5B" ID="ID_1418376563" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT10B: 3.1-fold Down; FDR = 0.0148; PValue = 0.00369; mean CPM = 1.086; wingless-type MMTV integration site family, member 10B" ID="ID_238257924" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TCF7: 1.72-fold Down; FDR = 0.0376; PValue = 0.011; mean CPM = 4.279; transcription factor 7 (T-cell specific, HMG-box)" ID="ID_1802651652" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTNNB1: 1.2-fold Up; FDR = 0.0498; PValue = 0.0153; mean CPM = 558.3; catenin (cadherin-associated protein), beta 1, 88kDa" ID="ID_1793912246" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT4: 1.52-fold Down; FDR = 0.0525; PValue = 0.0163; mean CPM = 13.66; wingless-type MMTV integration site family, member 4" ID="ID_1853382141" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TCF7L1: 1.2-fold Down; FDR = 0.0783; PValue = 0.0262; mean CPM = 25.11; transcription factor 7-like 1 (T-cell specific, HMG-box)" ID="ID_817283564" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BMP4: 1.86-fold Down; FDR = 0.119; PValue = 0.0432; mean CPM = 2.163; bone morphogenetic protein 4" ID="ID_1025977906" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_1081959663" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD1: 1.23-fold Down; FDR = 0.154; PValue = 0.0592; mean CPM = 31.65; frizzled homolog 1 (Drosophila)" ID="ID_458986530" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT3A: 2.28-fold Down; FDR = 0.2; PValue = 0.0823; mean CPM = 0.8811; wingless-type MMTV integration site family, member 3A" ID="ID_131421342" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GLI3: 1.21-fold Down; FDR = 0.211; PValue = 0.0875; mean CPM = 42.23; GLI family zinc finger 3" ID="ID_222661616" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT3: 1.4-fold Up; FDR = 0.304; PValue = 0.138; mean CPM = 1.843; wingless-type MMTV integration site family, member 3" ID="ID_792245140" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTCH1: 1.14-fold Down; FDR = 0.32; PValue = 0.147; mean CPM = 13.18; patched homolog 1 (Drosophila)" ID="ID_348502600" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD6: 1.11-fold Down; FDR = 0.347; PValue = 0.162; mean CPM = 39.10; frizzled homolog 6 (Drosophila)" ID="ID_1013932556" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD5: 1.34-fold Down; FDR = 0.405; PValue = 0.197; mean CPM = 2.107; frizzled homolog 5 (Drosophila)" ID="ID_624479934" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT9A: 1.43-fold Down; FDR = 0.505; PValue = 0.262; mean CPM = 2.172; wingless-type MMTV integration site family, member 9A" ID="ID_256589237" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT2B: 1.29-fold Down; FDR = 0.621; PValue = 0.345; mean CPM = 1.575; wingless-type MMTV integration site family, member 2B" ID="ID_1998550644" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LEF1: 1.2-fold Up; FDR = 0.691; PValue = 0.4; mean CPM = 2.488; lymphoid enhancer-binding factor 1" ID="ID_1390584944" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DVL2: 1.06-fold Up; FDR = 0.708; PValue = 0.414; mean CPM = 30.54; dishevelled, dsh homolog 2 (Drosophila)" ID="ID_1371135807" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HHIP: 1.36-fold Down; FDR = 0.764; PValue = 0.462; mean CPM = 0.9041; hedgehog interacting protein" ID="ID_1522284332" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT16: 1.27-fold Down; FDR = 0.857; PValue = 0.571; mean CPM = 0.9003; wingless-type MMTV integration site family, member 16" ID="ID_517832530" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT11: 1.18-fold Up; FDR = 0.903; PValue = 0.641; mean CPM = 1.340; wingless-type MMTV integration site family, member 11" ID="ID_1806986857" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GLI1: 1.1-fold Down; FDR = 0.956; PValue = 0.787; mean CPM = 1.155; GLI family zinc finger 1" ID="ID_1429898075" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT8B: 1.21-fold Down; FDR = 0.987; PValue = 0.838; mean CPM = 0.8506; wingless-type MMTV integration site family, member 8B" ID="ID_1666678629" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT2: 1.07-fold Down; FDR = 1; PValue = 0.888; mean CPM = 0.8103; wingless-type MMTV integration site family member 2" ID="ID_941462110" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD3: 1.03-fold Up; FDR = 1; PValue = 0.903; mean CPM = 1.636; frizzled homolog 3 (Drosophila)" ID="ID_967270695" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD10: 1.04-fold Down; FDR = 1; PValue = 0.919; mean CPM = 0.8435; frizzled homolog 10 (Drosophila)" ID="ID_1031407210" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT6: 1.13-fold Down; FDR = 1; PValue = 0.956; mean CPM = 0.8230; wingless-type MMTV integration site family, member 6" ID="ID_1426339124" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT9B: 1.03-fold Up; FDR = 1; PValue = 0.991; mean CPM = 0.8041; wingless-type MMTV integration site family, member 9B" ID="ID_188991457" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Legionellosis: Activated, FDR = 0.0274, FWER = 0.74, PValue = 0.0051" ID="ID_1856697659" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TLR2: 8.94-fold Up; FDR = 6.97e-23; PValue = 1.25e-25; mean CPM = 18.41; toll-like receptor 2" ID="ID_1828908765" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA2: 4.21-fold Down; FDR = 2.4e-14; PValue = 2.77e-16; mean CPM = 66.42; heat shock 70kDa protein 2" ID="ID_951964329" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR4: 3.45-fold Up; FDR = 3.1e-09; PValue = 1.19e-10; mean CPM = 7.456; Macaca mulatta toll-like receptor 4 (TLR4), mRNA." ID="ID_1626334976" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA1B: 2.24-fold Down; FDR = 4.33e-09; PValue = 1.71e-10; mean CPM = 44.90; Heat shock 70 kDa protein 1A/1B (Heat shock 70 kDa protein 1/2)(HSP70.1/HSP70.2)(HSP70-1/HSP70-2)" ID="ID_998726037" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA8: 1.64-fold Up; FDR = 1.46e-08; PValue = 6.6e-10; mean CPM = 1881; heat shock 70kDa protein 8" ID="ID_302443856" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_144771825" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLRC4: 6.6-fold Up; FDR = 8.52e-08; PValue = 4.67e-09; mean CPM = 3.347; NLR family, CARD domain containing 4" ID="ID_295567898" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_907182474" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD14: 2.75-fold Down; FDR = 6.54e-07; PValue = 4.46e-08; mean CPM = 5.195; CD14 molecule" ID="ID_1975223337" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL3: 3.28-fold Up; FDR = 0.00459; PValue = 0.000963; mean CPM = 50.55; chemokine (C-X-C motif) ligand 3" ID="ID_1949512614" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_423141014" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL1: 2.18-fold Up; FDR = 0.00609; PValue = 0.00133; mean CPM = 45.92; chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)" ID="ID_77515191" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR5: 1.86-fold Down; FDR = 0.00878; PValue = 0.00203; mean CPM = 3.008; toll-like receptor 5" ID="ID_674432988" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12A: 2.09-fold Up; FDR = 0.00924; PValue = 0.00215; mean CPM = 2.872; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)" ID="ID_1384647971" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL18: 1.5-fold Down; FDR = 0.00981; PValue = 0.0023; mean CPM = 6.489; interleukin 18 (interferon-gamma-inducing factor)" ID="ID_1471233669" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EEF1A1: 1.29-fold Up; FDR = 0.0127; PValue = 0.00309; mean CPM = 5042; eukaryotic translation elongation factor 1 alpha 1 pseudogene 9" ID="ID_371099418" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB2: 1.55-fold Down; FDR = 0.0187; PValue = 0.00485; mean CPM = 34.87; Integrin beta" ID="ID_945039762" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL8: 2.33-fold Up; FDR = 0.0209; PValue = 0.00552; mean CPM = 2326; interleukin 8" ID="ID_791618782" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA6: 2.05-fold Down; FDR = 0.0226; PValue = 0.00604; mean CPM = 2.573; heat shock 70kDa protein 6 (HSP70B')" ID="ID_794552672" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1986013401" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP7: 1.15-fold Up; FDR = 0.218; PValue = 0.0916; mean CPM = 21.49; caspase 7, apoptosis-related cysteine peptidase" ID="ID_153124208" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000039103: 1.67-fold Down; FDR = 0.221; PValue = 0.0927; mean CPM = 1.310; Uncharacterized protein" ID="ID_567295794" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CR1: 1.99-fold Up; FDR = 0.225; PValue = 0.095; mean CPM = 0.9520; Uncharacterized protein" ID="ID_424514582" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PYCARD: 1.38-fold Down; FDR = 0.241; PValue = 0.103; mean CPM = 3.110; PYD and CARD domain containing" ID="ID_1626439807" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_1748863665" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAM: 1.44-fold Down; FDR = 0.73; PValue = 0.432; mean CPM = 0.9052; integrin, alpha M (complement component 3 receptor 3 subunit)" ID="ID_1861652078" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_267698100" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APAF1: 1.05-fold Down; FDR = 0.837; PValue = 0.543; mean CPM = 32.11; apoptotic peptidase activating factor 1" ID="ID_1935674467" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYCS: 1.05-fold Up; FDR = 0.854; PValue = 0.565; mean CPM = 93.43; cytochrome c, somatic" ID="ID_1149272927" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000040219: 1.08-fold Up; FDR = 0.86; PValue = 0.575; mean CPM = 8.818; Uncharacterized protein" ID="ID_1947666698" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_290789552" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000009289: 1.07-fold Up; FDR = 0.963; PValue = 0.798; mean CPM = 2.536; Uncharacterized protein" ID="ID_904939049" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSF1: 1.02-fold Up; FDR = 0.966; PValue = 0.804; mean CPM = 64.76; heat shock transcription factor 1" ID="ID_811302318" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12B: 1.07-fold Up; FDR = 0.983; PValue = 0.831; mean CPM = 0.8197; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)" ID="ID_1016115445" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP9: 1.01-fold Up; FDR = 1; PValue = 0.908; mean CPM = 19.86; caspase 9, apoptosis-related cysteine peptidase" ID="ID_735150290" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014292: No Change; FDR = 1; PValue = 1; mean CPM = 0.7827; Uncharacterized protein" ID="ID_574887778" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Tuberculosis: Activated, FDR = 0.0382, FWER = 1, PValue = 0.00737" ID="ID_1155442933" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TLR2: 8.94-fold Up; FDR = 6.97e-23; PValue = 1.25e-25; mean CPM = 18.41; toll-like receptor 2" ID="ID_1631632905" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_1266453952" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_864597583" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CIITA: 45.8-fold Up; FDR = 1.14e-17; PValue = 7.44e-20; mean CPM = 27.80; class II, major histocompatibility complex, transactivator" ID="ID_649182624" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD74: 104-fold Up; FDR = 6e-17; PValue = 4.54e-19; mean CPM = 141.5; CD74 molecule, major histocompatibility complex, class II invariant chain" ID="ID_555623972" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_499535043" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK2: 3.75-fold Up; FDR = 6.1e-16; PValue = 5.38e-18; mean CPM = 68.21; receptor-interacting serine-threonine kinase 2" ID="ID_267410616" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP6V0A1: 2.41-fold Down; FDR = 1.81e-15; PValue = 1.67e-17; mean CPM = 68.72; ATPase, H+ transporting, lysosomal V0 subunit a1" ID="ID_1175181632" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DMB: 17.5-fold Up; FDR = 2.77e-15; PValue = 2.66e-17; mean CPM = 9.464; HLA class II histocompatibility antigen, DM beta chain Precursor (MHC class II antigen DMB)(Really interesting new gene 7 protein)" ID="ID_404588412" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DPA1: 107-fold Up; FDR = 5.97e-15; PValue = 6.11e-17; mean CPM = 17.08; HLA class II histocompatibility antigen, DP alpha 1 chain Precursor (HLA-SB alpha chain)(MHC class II DP3-alpha)(DP(W3))(DP(W4))" ID="ID_1173351206" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DQB1: 31.1-fold Up; FDR = 6.93e-13; PValue = 1.1e-14; mean CPM = 6.675; Macaca mulatta MHC class II antigen (MAMU-DRB), mRNA." ID="ID_1405733151" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB3: 4.82-fold Down; FDR = 1.82e-12; PValue = 3.09e-14; mean CPM = 9.911; transforming growth factor, beta 3" ID="ID_1407030898" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MRC2: 2.12-fold Down; FDR = 1.81e-10; PValue = 5.07e-12; mean CPM = 772.3; mannose receptor, C type 2" ID="ID_1743363709" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA9: 1.88-fold Up; FDR = 1.83e-10; PValue = 5.13e-12; mean CPM = 417.2; heat shock 70kDa protein 9 (mortalin)" ID="ID_1484286357" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR4: 3.45-fold Up; FDR = 3.1e-09; PValue = 1.19e-10; mean CPM = 7.456; Macaca mulatta toll-like receptor 4 (TLR4), mRNA." ID="ID_1993857449" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BID: 1.66-fold Up; FDR = 5.41e-09; PValue = 2.19e-10; mean CPM = 35.19; BH3 interacting domain death agonist" ID="ID_683114928" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP6AP1: 1.65-fold Down; FDR = 1.8e-08; PValue = 8.33e-10; mean CPM = 82.41; ATPase, H+ transporting, lysosomal accessory protein 1" ID="ID_1827552293" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA1: 15.1-fold Up; FDR = 1.9e-08; PValue = 8.86e-10; mean CPM = 3.665; HLA class II histocompatibility antigen, DQ alpha 1 chain precursor" ID="ID_144242983" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK4: 1.8-fold Up; FDR = 3.31e-08; PValue = 1.64e-09; mean CPM = 12.89; interleukin-1 receptor-associated kinase 4" ID="ID_316201189" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1396920668" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAMK2D: 1.54-fold Up; FDR = 4.06e-08; PValue = 2.07e-09; mean CPM = 51.52; calcium/calmodulin-dependent protein kinase II delta" ID="ID_423642955" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DPB1: 7.73-fold Up; FDR = 4.73e-08; PValue = 2.45e-09; mean CPM = 1.528; Macaca mulatta major histocompatibility complex, class II, DP beta (MAMU-DPB), mRNA." ID="ID_1784642689" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_984349510" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPD1: 1.89-fold Up; FDR = 4.72e-07; PValue = 3.11e-08; mean CPM = 291.5; Uncharacterized protein" ID="ID_1441609037" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD14: 2.75-fold Down; FDR = 6.54e-07; PValue = 4.46e-08; mean CPM = 5.195; CD14 molecule" ID="ID_1185534888" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_1332978212" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RFX5: 1.45-fold Up; FDR = 2.02e-06; PValue = 1.58e-07; mean CPM = 51.69; regulatory factor X, 5 (influences HLA class II expression)" ID="ID_1120782888" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1000752631" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL10: 1.55-fold Up; FDR = 5.92e-06; PValue = 5.22e-07; mean CPM = 21.83; B-cell CLL/lymphoma 10" ID="ID_1121091830" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP6V0D1: 1.57-fold Down; FDR = 1.06e-05; PValue = 9.98e-07; mean CPM = 36.69; ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1" ID="ID_1724285822" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CEBPG: 1.5-fold Up; FDR = 1.48e-05; PValue = 1.46e-06; mean CPM = 31.57; CCAAT/enhancer binding protein (C/EBP), gamma" ID="ID_1415924980" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP6V0C: 1.42-fold Down; FDR = 4.49e-05; PValue = 5.01e-06; mean CPM = 60.49; ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c" ID="ID_686752596" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CARD9: 1.53-fold Up; FDR = 9.57e-05; PValue = 1.18e-05; mean CPM = 16.72; caspase recruitment domain family, member 9" ID="ID_999381524" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTSD: 1.65-fold Down; FDR = 0.000162; PValue = 2.13e-05; mean CPM = 578.9; cathepsin D" ID="ID_1668267874" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP3CA: 1.55-fold Up; FDR = 0.0003; PValue = 4.32e-05; mean CPM = 40.21; protein phosphatase 3, catalytic subunit, alpha isozyme" ID="ID_524520307" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAD: 1.36-fold Down; FDR = 0.000605; PValue = 9.52e-05; mean CPM = 48.46; BCL2-associated agonist of cell death" ID="ID_1227800208" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALM3: 1.41-fold Down; FDR = 0.000714; PValue = 0.000115; mean CPM = 94.24; calmodulin 3 (phosphorylase kinase, delta)" ID="ID_985147125" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMP1: 1.31-fold Down; FDR = 0.00116; PValue = 0.0002; mean CPM = 320.9; lysosomal-associated membrane protein 1" ID="ID_25697498" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAMK2A: 2.29-fold Down; FDR = 0.00124; PValue = 0.000217; mean CPM = 2.001; calcium/calmodulin-dependent protein kinase II alpha" ID="ID_229685517" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR1: 1.31-fold Up; FDR = 0.00151; PValue = 0.000268; mean CPM = 37.77; interferon gamma receptor 1" ID="ID_1620061179" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHOA: 1.28-fold Down; FDR = 0.00295; PValue = 0.000575; mean CPM = 277.8; ras homolog gene family, member A" ID="ID_963238572" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAMK2B: 3.82-fold Down; FDR = 0.00536; PValue = 0.00115; mean CPM = 1.542; calcium/calmodulin-dependent protein kinase II beta" ID="ID_1530361342" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_789252664" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12A: 2.09-fold Up; FDR = 0.00924; PValue = 0.00215; mean CPM = 2.872; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)" ID="ID_253197612" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL18: 1.5-fold Down; FDR = 0.00981; PValue = 0.0023; mean CPM = 6.489; interleukin 18 (interferon-gamma-inducing factor)" ID="ID_525746151" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAB5A: 1.27-fold Up; FDR = 0.00988; PValue = 0.00232; mean CPM = 24.19; Uncharacterized protein" ID="ID_834483835" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAB7B: 1.54-fold Down; FDR = 0.0162; PValue = 0.00413; mean CPM = 7.015; Uncharacterized protein" ID="ID_1151646530" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP10: 1.81-fold Up; FDR = 0.0175; PValue = 0.0045; mean CPM = 2.876; caspase 10, apoptosis-related cysteine peptidase" ID="ID_900313868" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB2: 1.55-fold Down; FDR = 0.0187; PValue = 0.00485; mean CPM = 34.87; Integrin beta" ID="ID_1521596371" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1989595422" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLK3: 1.27-fold Down; FDR = 0.0251; PValue = 0.00684; mean CPM = 26.43; polo-like kinase 3 (Drosophila)" ID="ID_99763014" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1367352302" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR2: 1.23-fold Up; FDR = 0.0258; PValue = 0.00707; mean CPM = 46.52; interferon gamma receptor 2 (interferon gamma transducer 1)" ID="ID_167482158" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLA2R1: 1.21-fold Down; FDR = 0.0262; PValue = 0.00719; mean CPM = 166.0; Uncharacterized protein" ID="ID_1707688560" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARHGEF12: 1.21-fold Up; FDR = 0.0298; PValue = 0.00837; mean CPM = 203.3; Rho guanine nucleotide exchange factor (GEF) 12" ID="ID_1618699948" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB1: 1.21-fold Up; FDR = 0.0313; PValue = 0.00884; mean CPM = 36.07; cAMP responsive element binding protein 1" ID="ID_354695468" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRADD: 1.22-fold Up; FDR = 0.0319; PValue = 0.00907; mean CPM = 34.75; TNFRSF1A-associated via death domain" ID="ID_1987318031" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_854510516" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DOA: 2.74-fold Up; FDR = 0.0694; PValue = 0.0227; mean CPM = 0.9089; HLA class II histocompatibility antigen, DO alpha chain Precursor (MHC class II antigen DOA)(MHC DZ alpha)(MHC DN-alpha)" ID="ID_917852664" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAB5A: 1.17-fold Up; FDR = 0.0885; PValue = 0.0303; mean CPM = 164.1; RAB5A, member RAS oncogene family" ID="ID_483856166" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FADD: 1.18-fold Down; FDR = 0.0936; PValue = 0.0324; mean CPM = 30.89; Uncharacterized protein" ID="ID_989614737" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_1848483753" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALM1: 1.18-fold Down; FDR = 0.104; PValue = 0.0368; mean CPM = 292.9; calmodulin 1 (phosphorylase kinase, delta)" ID="ID_1598323582" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_552250525" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000004442: 1.28-fold Down; FDR = 0.152; PValue = 0.0584; mean CPM = 25.35; Putative uncharacterized protein" ID="ID_190822837" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RFXANK: 1.15-fold Up; FDR = 0.166; PValue = 0.0651; mean CPM = 33.20; regulatory factor X-associated ankyrin-containing protein" ID="ID_1123744834" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EEA1: 1.14-fold Down; FDR = 0.167; PValue = 0.0656; mean CPM = 69.68; early endosome antigen 1" ID="ID_725673702" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFYA: 1.14-fold Up; FDR = 0.174; PValue = 0.069; mean CPM = 34.54; nuclear transcription factor Y, alpha" ID="ID_1231877044" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TCIRG1: 1.13-fold Up; FDR = 0.203; PValue = 0.0838; mean CPM = 92.84; Uncharacterized protein" ID="ID_633912749" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000039103: 1.67-fold Down; FDR = 0.221; PValue = 0.0927; mean CPM = 1.310; Uncharacterized protein" ID="ID_311448829" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CR1: 1.99-fold Up; FDR = 0.225; PValue = 0.095; mean CPM = 0.9520; Uncharacterized protein" ID="ID_1801588683" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAB7A: 1.12-fold Down; FDR = 0.229; PValue = 0.097; mean CPM = 112.6; RAB7A, member RAS oncogene family" ID="ID_1286363015" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK2: 1.27-fold Down; FDR = 0.259; PValue = 0.113; mean CPM = 10.13; interleukin-1 receptor-associated kinase 2" ID="ID_1508756036" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_1414086977" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1A: 1.11-fold Up; FDR = 0.297; PValue = 0.134; mean CPM = 134.7; tumor necrosis factor receptor superfamily, member 1A" ID="ID_1845126911" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1A: 1.5-fold Up; FDR = 0.315; PValue = 0.144; mean CPM = 155.4; interleukin 1, alpha" ID="ID_1448105512" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALM1: 1.11-fold Up; FDR = 0.343; PValue = 0.16; mean CPM = 412.7; Calmodulin; Uncharacterized protein" ID="ID_1144506381" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL23A: 1.39-fold Up; FDR = 0.348; PValue = 0.163; mean CPM = 4.542; interleukin 23, alpha subunit p19" ID="ID_726555316" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MALT1: 1.11-fold Down; FDR = 0.35; PValue = 0.164; mean CPM = 42.89; mucosa associated lymphoid tissue lymphoma translocation gene 1" ID="ID_272820539" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014796: 1.77-fold Up; FDR = 0.381; PValue = 0.182; mean CPM = 0.9085; Uncharacterized protein" ID="ID_995181304" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2: 1.48-fold Up; FDR = 0.384; PValue = 0.184; mean CPM = 1.344; Uncharacterized protein" ID="ID_1623678766" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_1028241145" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1944933298" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK12: 1.19-fold Down; FDR = 0.422; PValue = 0.208; mean CPM = 6.569; mitogen-activated protein kinase 12" ID="ID_1340759459" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1909819051" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP3CB: 1.08-fold Up; FDR = 0.514; PValue = 0.268; mean CPM = 76.44; protein phosphatase 3, catalytic subunit, beta isozyme" ID="ID_98474680" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL10RA: 1.55-fold Down; FDR = 0.516; PValue = 0.269; mean CPM = 0.9545; interleukin 10 receptor, alpha" ID="ID_1838479404" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK13: 1.22-fold Down; FDR = 0.536; PValue = 0.284; mean CPM = 3.100; mitogen-activated protein kinase 13" ID="ID_1451215370" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFYB: 1.1-fold Up; FDR = 0.547; PValue = 0.292; mean CPM = 15.90; nuclear transcription factor Y, beta" ID="ID_729179994" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RFXAP: 1.18-fold Up; FDR = 0.553; PValue = 0.296; mean CPM = 3.588; regulatory factor X-associated protein" ID="ID_1038947464" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAB5B: 1.07-fold Up; FDR = 0.646; PValue = 0.364; mean CPM = 60.61; RAB5B, member RAS oncogene family" ID="ID_1304293333" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_1906275248" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAM: 1.44-fold Down; FDR = 0.73; PValue = 0.432; mean CPM = 0.9052; integrin, alpha M (complement component 3 receptor 3 subunit)" ID="ID_997231864" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNB1: 1.79-fold Up; FDR = 0.731; PValue = 0.433; mean CPM = 0.8526; interferon, beta 1, fibroblast" ID="ID_53926477" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_1243825696" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP6V0A2: 1.06-fold Down; FDR = 0.794; PValue = 0.49; mean CPM = 21.01; ATPase, H+ transporting, lysosomal V0 subunit a2" ID="ID_878134525" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA6: 1.41-fold Down; FDR = 0.807; PValue = 0.504; mean CPM = 0.8019; interferon, alpha 6" ID="ID_390846176" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAX: 1.05-fold Up; FDR = 0.809; PValue = 0.506; mean CPM = 162.4; Uncharacterized protein" ID="ID_953658258" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALML5: 1.49-fold Up; FDR = 0.819; PValue = 0.518; mean CPM = 0.8129; calmodulin-like 5" ID="ID_1752025552" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APAF1: 1.05-fold Down; FDR = 0.837; PValue = 0.543; mean CPM = 32.11; apoptotic peptidase activating factor 1" ID="ID_427750290" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR6: 1.07-fold Down; FDR = 0.84; PValue = 0.546; mean CPM = 7.909; toll-like receptor 6" ID="ID_1117549585" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD209: 1.49-fold Down; FDR = 0.84; PValue = 0.547; mean CPM = 0.8492; CD209 antigen isoform 1" ID="ID_1320821009" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TIRAP: 1.07-fold Up; FDR = 0.841; PValue = 0.548; mean CPM = 8.693; Macaca mulatta toll-interleukin 1 receptor (TIR) domain containing adaptor protein (TIRAP), mRNA." ID="ID_1820616276" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYCS: 1.05-fold Up; FDR = 0.854; PValue = 0.565; mean CPM = 93.43; cytochrome c, somatic" ID="ID_1848456568" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYP27B1: 1.09-fold Up; FDR = 0.856; PValue = 0.569; mean CPM = 3.584; cytochrome P450, family 27, subfamily B, polypeptide 1" ID="ID_1846214595" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000040219: 1.08-fold Up; FDR = 0.86; PValue = 0.575; mean CPM = 8.818; Uncharacterized protein" ID="ID_1534065322" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP6V1H: 1.04-fold Down; FDR = 0.862; PValue = 0.578; mean CPM = 53.43; ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H" ID="ID_1724170191" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOD2: 1.17-fold Up; FDR = 0.866; PValue = 0.583; mean CPM = 1.911; nucleotide-binding oligomerization domain containing 2" ID="ID_1094397280" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK1: 1.04-fold Down; FDR = 0.885; PValue = 0.606; mean CPM = 41.54; interleukin-1 receptor-associated kinase 1" ID="ID_241493382" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALML6: 1.1-fold Up; FDR = 0.888; PValue = 0.61; mean CPM = 6.655; calmodulin-like 6" ID="ID_526730688" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_1501763845" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DRB: 1.28-fold Up; FDR = 0.898; PValue = 0.624; mean CPM = 0.8112; MHC class II antigen; Uncharacterized protein" ID="ID_1146137846" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_328195804" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB2: 1.05-fold Down; FDR = 0.903; PValue = 0.655; mean CPM = 110.8; transforming growth factor, beta 2" ID="ID_1478329939" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA13: 1.13-fold Up; FDR = 0.908; PValue = 0.677; mean CPM = 0.7960; interferon, alpha 13" ID="ID_1503151021" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA2: 1.13-fold Up; FDR = 0.908; PValue = 0.681; mean CPM = 0.7877; HLA class II histocompatibility antigen, DQ alpha 2 chain Precursor (HLA class II histocompatibility antigen, DQ(6) alpha chain)(DX alpha chain)(HLA-DQA1)" ID="ID_559482653" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALML3: 1.41-fold Down; FDR = 0.911; PValue = 0.698; mean CPM = 0.8159; calmodulin-like 3" ID="ID_1442065475" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA8: 1.13-fold Down; FDR = 0.911; PValue = 0.702; mean CPM = 0.7910; interferon, alpha 8" ID="ID_1262855334" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMP2: 1.03-fold Up; FDR = 0.912; PValue = 0.707; mean CPM = 96.61; lysosomal-associated membrane protein 2" ID="ID_1667150186" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOS2: 1.4-fold Down; FDR = 0.917; PValue = 0.718; mean CPM = 0.8546; nitric oxide synthase 2, inducible" ID="ID_1140228815" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB1: 1.02-fold Down; FDR = 0.936; PValue = 0.749; mean CPM = 62.61; transforming growth factor, beta 1" ID="ID_247625855" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_223703014" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000009289: 1.07-fold Up; FDR = 0.963; PValue = 0.798; mean CPM = 2.536; Uncharacterized protein" ID="ID_768752101" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA14: 1.22-fold Up; FDR = 0.965; PValue = 0.802; mean CPM = 0.8654; interferon, alpha 14" ID="ID_1971972918" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016883: 1.11-fold Down; FDR = 0.97; PValue = 0.811; mean CPM = 0.8838; Uncharacterized protein" ID="ID_1779680312" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA4: 1.28-fold Down; FDR = 0.983; PValue = 0.829; mean CPM = 0.8584; interferon, alpha 4" ID="ID_490691562" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12B: 1.07-fold Up; FDR = 0.983; PValue = 0.831; mean CPM = 0.8197; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)" ID="ID_1792087835" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP6V0A4: 1.09-fold Down; FDR = 0.986; PValue = 0.835; mean CPM = 0.8982; ATPase, H+ transporting, lysosomal V0 subunit a4" ID="ID_1442082066" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR9: 1.01-fold Down; FDR = 1; PValue = 0.859; mean CPM = 21.45; Macaca mulatta toll-like receptor 9 (TLR9), mRNA." ID="ID_914229920" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAMP: 1.07-fold Up; FDR = 1; PValue = 0.888; mean CPM = 0.8120; Macaca mulatta cathelicidin antimicrobial peptide (CAMP), mRNA." ID="ID_4411422" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP9: 1.01-fold Up; FDR = 1; PValue = 0.908; mean CPM = 19.86; caspase 9, apoptosis-related cysteine peptidase" ID="ID_997161845" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP6V0D2: 1.03-fold Down; FDR = 1; PValue = 0.935; mean CPM = 1.262; ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2" ID="ID_1346090250" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR1: 1.02-fold Up; FDR = 1; PValue = 0.945; mean CPM = 1.221; toll-like receptor 1" ID="ID_156493237" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL10: 1.21-fold Down; FDR = 1; PValue = 0.964; mean CPM = 0.8614; interleukin 10" ID="ID_927037108" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SYK: 1.11-fold Up; FDR = 1; PValue = 0.977; mean CPM = 0.8420; spleen tyrosine kinase" ID="ID_881150762" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLEC7A: 1.08-fold Up; FDR = 1; PValue = 0.978; mean CPM = 0.8142; Macaca mulatta C-type lectin domain family 7, member A (CLEC7A), mRNA." ID="ID_13806593" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA1: No Change; FDR = 1; PValue = 0.998; mean CPM = 0.8014; interferon, alpha 1" ID="ID_1344074428" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLEC4E: No Change; FDR = 1; PValue = 1; mean CPM = 0.7851; C-type lectin domain family 4, member E" ID="ID_135657737" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg NOD-like receptor signaling pathway: Activated, FDR = 0.0406, FWER = 1, PValue = 0.00813" ID="ID_561755962" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CASP5: 68-fold Up; FDR = 3.54e-19; PValue = 1.64e-21; mean CPM = 7.240; caspase 5, apoptosis-related cysteine peptidase" ID="ID_299773296" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_963559411" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK2: 3.75-fold Up; FDR = 6.1e-16; PValue = 5.38e-18; mean CPM = 68.21; receptor-interacting serine-threonine kinase 2" ID="ID_1307266583" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CARD6: 2.33-fold Up; FDR = 1.15e-12; PValue = 1.89e-14; mean CPM = 30.09; caspase recruitment domain family, member 6" ID="ID_288848563" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CARD8: 2.48-fold Up; FDR = 2.44e-11; PValue = 5.59e-13; mean CPM = 14.84; caspase recruitment domain family, member 8" ID="ID_156732503" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC2: 1.96-fold Up; FDR = 1.01e-10; PValue = 2.62e-12; mean CPM = 53.58; baculoviral IAP repeat-containing 2" ID="ID_1360047789" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CARD8: 2.02-fold Up; FDR = 1.41e-09; PValue = 4.93e-11; mean CPM = 15.89; caspase recruitment domain family, member 8" ID="ID_1316676332" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_850863900" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLRC4: 6.6-fold Up; FDR = 8.52e-08; PValue = 4.67e-09; mean CPM = 3.347; NLR family, CARD domain containing 4" ID="ID_1010159663" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC3: 2.79-fold Up; FDR = 1.74e-06; PValue = 1.32e-07; mean CPM = 95.34; baculoviral IAP repeat-containing 3" ID="ID_1300587100" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_308904382" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFAIP3: 1.79-fold Up; FDR = 3.14e-05; PValue = 3.34e-06; mean CPM = 52.47; tumor necrosis factor, alpha-induced protein 3" ID="ID_970681714" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90AA1: 1.41-fold Up; FDR = 4.17e-05; PValue = 4.62e-06; mean CPM = 609.6; heat shock protein 90kDa alpha (cytosolic), class A member 2" ID="ID_653564040" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CARD9: 1.53-fold Up; FDR = 9.57e-05; PValue = 1.18e-05; mean CPM = 16.72; caspase recruitment domain family, member 9" ID="ID_108077117" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP2: 1.45-fold Up; FDR = 0.000179; PValue = 2.4e-05; mean CPM = 65.31; TGF-beta activated kinase 1/MAP3K7 binding protein 2" ID="ID_1110826526" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOD1: 1.63-fold Up; FDR = 0.000193; PValue = 2.61e-05; mean CPM = 58.36; nucleotide-binding oligomerization domain containing 1" ID="ID_1644220989" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SUGT1: 1.35-fold Up; FDR = 0.000193; PValue = 2.61e-05; mean CPM = 54.75; SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)" ID="ID_1939599211" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP3: 1.5-fold Up; FDR = 0.000276; PValue = 3.92e-05; mean CPM = 11.67; TGF-beta activated kinase 1/MAP3K7 binding protein 3" ID="ID_1793145966" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_55267582" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90B1: 1.28-fold Down; FDR = 0.00538; PValue = 0.00115; mean CPM = 1017; heat shock protein 90kDa beta (Grp94), member 1" ID="ID_535542370" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_868589112" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1297998677" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1883363035" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_380775333" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_1737080206" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PYCARD: 1.38-fold Down; FDR = 0.241; PValue = 0.103; mean CPM = 3.110; PYD and CARD domain containing" ID="ID_1863241649" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLRP3: 1.84-fold Down; FDR = 0.32; PValue = 0.147; mean CPM = 0.9630; NLR family, pyrin domain containing 3" ID="ID_1346670072" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP1: 1.12-fold Down; FDR = 0.351; PValue = 0.165; mean CPM = 17.96; TGF-beta activated kinase 1/MAP3K7 binding protein 1" ID="ID_1688656576" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_1282479931" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_789747392" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK12: 1.19-fold Down; FDR = 0.422; PValue = 0.208; mean CPM = 6.569; mitogen-activated protein kinase 12" ID="ID_640870963" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1603590136" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK13: 1.22-fold Down; FDR = 0.536; PValue = 0.284; mean CPM = 3.100; mitogen-activated protein kinase 13" ID="ID_1730828365" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90AB1: 1.07-fold Down; FDR = 0.652; PValue = 0.369; mean CPM = 905.8; heat shock protein 90kDa alpha (cytosolic), class B member 1" ID="ID_955520034" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90AA1: 1.8-fold Up; FDR = 0.749; PValue = 0.449; mean CPM = 0.8328; heat shock protein 90kDa alpha (cytosolic), class A member 1" ID="ID_406597662" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MEFV: 1.13-fold Up; FDR = 0.813; PValue = 0.51; mean CPM = 6.740; Mediterranean fever" ID="ID_292375302" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1598363730" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOD2: 1.17-fold Up; FDR = 0.866; PValue = 0.583; mean CPM = 1.911; nucleotide-binding oligomerization domain containing 2" ID="ID_1842435688" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_908167840" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRIP6: 1.01-fold Down; FDR = 1; PValue = 0.92; mean CPM = 125.6; thyroid hormone receptor interactor 6" ID="ID_1493863266" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSTPIP1: 1.03-fold Down; FDR = 1; PValue = 0.929; mean CPM = 1.615; proline-serine-threonine phosphatase interacting protein 1" ID="ID_409659835" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_1237789164" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Leishmaniasis: Activated, FDR = 0.0523, FWER = 1, PValue = 0.0109" ID="ID_734128728" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TLR2: 8.94-fold Up; FDR = 6.97e-23; PValue = 1.25e-25; mean CPM = 18.41; toll-like receptor 2" ID="ID_31495884" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_418378824" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_820542929" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB3: 4.82-fold Down; FDR = 1.82e-12; PValue = 3.09e-14; mean CPM = 9.911; transforming growth factor, beta 3" ID="ID_518698143" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR4: 3.45-fold Up; FDR = 3.1e-09; PValue = 1.19e-10; mean CPM = 7.456; Macaca mulatta toll-like receptor 4 (TLR4), mRNA." ID="ID_585069973" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK4: 1.8-fold Up; FDR = 3.31e-08; PValue = 1.64e-09; mean CPM = 12.89; interleukin-1 receptor-associated kinase 4" ID="ID_1503639516" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_377709998" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP2: 1.45-fold Up; FDR = 0.000179; PValue = 2.4e-05; mean CPM = 65.31; TGF-beta activated kinase 1/MAP3K7 binding protein 2" ID="ID_1138011472" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTGS2: 2.02-fold Up; FDR = 0.000254; PValue = 3.59e-05; mean CPM = 314.5; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)" ID="ID_663421547" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYBA: 1.34-fold Up; FDR = 0.00107; PValue = 0.000183; mean CPM = 376.6; cytochrome b-245, alpha polypeptide" ID="ID_1784912503" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR1: 1.31-fold Up; FDR = 0.00151; PValue = 0.000268; mean CPM = 37.77; interferon gamma receptor 1" ID="ID_765343673" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1754763691" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB2: 1.55-fold Down; FDR = 0.0187; PValue = 0.00485; mean CPM = 34.87; Integrin beta" ID="ID_1820807655" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1079863436" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FCGR2B: 2.01-fold Up; FDR = 0.0231; PValue = 0.00623; mean CPM = 1.743; Uncharacterized protein" ID="ID_573338678" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR2: 1.23-fold Up; FDR = 0.0258; PValue = 0.00707; mean CPM = 46.52; interferon gamma receptor 2 (interferon gamma transducer 1)" ID="ID_1674702821" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_168391143" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_371090902" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_604903090" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FCGR2A: 2.18-fold Up; FDR = 0.172; PValue = 0.0682; mean CPM = 0.9955; Fc fragment of IgG, low affinity IIa, receptor (CD32)" ID="ID_58030590" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CR1: 1.99-fold Up; FDR = 0.225; PValue = 0.095; mean CPM = 0.9520; Uncharacterized protein" ID="ID_236112714" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FCGR3A: 1.84-fold Down; FDR = 0.245; PValue = 0.106; mean CPM = 1.030; Fc fragment of IgG, low affinity IIIa, receptor (CD16a)" ID="ID_965782975" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP1: 1.12-fold Down; FDR = 0.351; PValue = 0.165; mean CPM = 17.96; TGF-beta activated kinase 1/MAP3K7 binding protein 1" ID="ID_491841243" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_200337556" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1516878890" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK12: 1.19-fold Down; FDR = 0.422; PValue = 0.208; mean CPM = 6.569; mitogen-activated protein kinase 12" ID="ID_1411841183" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_489024549" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCF2: 1.29-fold Up; FDR = 0.525; PValue = 0.276; mean CPM = 2.178; Uncharacterized protein" ID="ID_1578511921" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK13: 1.22-fold Down; FDR = 0.536; PValue = 0.284; mean CPM = 3.100; mitogen-activated protein kinase 13" ID="ID_1342245740" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCF4: 1.16-fold Up; FDR = 0.69; PValue = 0.399; mean CPM = 6.357; neutrophil cytosolic factor 4, 40kDa" ID="ID_379464467" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCB: 1.86-fold Up; FDR = 0.727; PValue = 0.43; mean CPM = 0.8705; protein kinase C, beta" ID="ID_1211462571" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAM: 1.44-fold Down; FDR = 0.73; PValue = 0.432; mean CPM = 0.9052; integrin, alpha M (complement component 3 receptor 3 subunit)" ID="ID_334315142" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK1: 1.04-fold Down; FDR = 0.885; PValue = 0.606; mean CPM = 41.54; interleukin-1 receptor-associated kinase 1" ID="ID_1548254342" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_424531809" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB2: 1.05-fold Down; FDR = 0.903; PValue = 0.655; mean CPM = 110.8; transforming growth factor, beta 2" ID="ID_1270682175" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOS2: 1.4-fold Down; FDR = 0.917; PValue = 0.718; mean CPM = 0.8546; nitric oxide synthase 2, inducible" ID="ID_1131251089" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL4: 1.27-fold Down; FDR = 0.933; PValue = 0.745; mean CPM = 0.8077; interleukin 4" ID="ID_924583643" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB1: 1.02-fold Down; FDR = 0.936; PValue = 0.749; mean CPM = 62.61; transforming growth factor, beta 1" ID="ID_1313867383" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_98488877" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000005832: 1.08-fold Up; FDR = 0.982; PValue = 0.828; mean CPM = 1.034; Uncharacterized protein" ID="ID_941164214" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_226403778" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL10: 1.21-fold Down; FDR = 1; PValue = 0.964; mean CPM = 0.8614; interleukin 10" ID="ID_1679879001" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Proteoglycans in cancer: Inhibited, FDR = 0.0523, FWER = 1, PValue = 0.0112" ID="ID_851254221" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TLR2: 8.94-fold Up; FDR = 6.97e-23; PValue = 1.25e-25; mean CPM = 18.41; toll-like receptor 2" ID="ID_317579055" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MRAS: 2.04-fold Up; FDR = 4.47e-15; PValue = 4.43e-17; mean CPM = 41.38; muscle RAS oncogene homolog" ID="ID_1226761623" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA5: 3.79-fold Down; FDR = 1.33e-14; PValue = 1.48e-16; mean CPM = 1237; integrin, alpha 5 (fibronectin receptor, alpha polypeptide)" ID="ID_1236443892" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF1: 5.05-fold Down; FDR = 8.21e-14; PValue = 1.05e-15; mean CPM = 19.54; fibroblast growth factor 1 (acidic)" ID="ID_1631507282" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MET: 2.57-fold Up; FDR = 3.56e-13; PValue = 5.22e-15; mean CPM = 242.4; Macaca mulatta met proto-oncogene (hepatocyte growth factor receptor) (MET), mRNA." ID="ID_1377749760" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_911556522" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD2: 2.27-fold Down; FDR = 5e-11; PValue = 1.24e-12; mean CPM = 20.66; frizzled homolog 2 (Drosophila)" ID="ID_1392323802" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAV: 2.64-fold Down; FDR = 6.04e-11; PValue = 1.51e-12; mean CPM = 337.3; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)" ID="ID_414826432" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLAU: 3.37-fold Down; FDR = 1.56e-10; PValue = 4.33e-12; mean CPM = 18.78; plasminogen activator, urokinase" ID="ID_1442317542" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MSN: 1.65-fold Down; FDR = 5.3e-10; PValue = 1.68e-11; mean CPM = 571.5; moesin" ID="ID_795755453" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA2: 2.84-fold Up; FDR = 7.38e-10; PValue = 2.42e-11; mean CPM = 176.3; integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)" ID="ID_660277388" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPG2: 2.83-fold Down; FDR = 8.45e-10; PValue = 2.83e-11; mean CPM = 1670; heparan sulfate proteoglycan 2" ID="ID_1620257271" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GPC1: 2.82-fold Down; FDR = 1.59e-09; PValue = 5.64e-11; mean CPM = 30.91; Glypican-1; Uncharacterized protein" ID="ID_1494250584" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB3: 5.02-fold Down; FDR = 1.72e-09; PValue = 6.17e-11; mean CPM = 43.21; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)" ID="ID_582874053" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR4: 3.45-fold Up; FDR = 3.1e-09; PValue = 1.19e-10; mean CPM = 7.456; Macaca mulatta toll-like receptor 4 (TLR4), mRNA." ID="ID_1282566827" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_1073792023" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGFR: 1.84-fold Up; FDR = 6.71e-09; PValue = 2.77e-10; mean CPM = 68.58; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)" ID="ID_1999842491" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SDC2: 1.91-fold Down; FDR = 6.94e-09; PValue = 2.87e-10; mean CPM = 168.5; syndecan 2" ID="ID_1218494453" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB5: 1.61-fold Down; FDR = 8.23e-09; PValue = 3.47e-10; mean CPM = 471.0; integrin, beta 5" ID="ID_1983897346" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF2: 2.42-fold Up; FDR = 9.98e-09; PValue = 4.31e-10; mean CPM = 134.8; fibroblast growth factor 2 (basic)" ID="ID_916312233" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HBEGF: 2.56-fold Down; FDR = 1.43e-08; PValue = 6.48e-10; mean CPM = 40.73; Proheparin-binding EGF-like growth factor; Uncharacterized protein" ID="ID_1396137459" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FLNA: 2.35-fold Down; FDR = 2.01e-08; PValue = 9.45e-10; mean CPM = 7159; filamin A, alpha" ID="ID_376670043" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAMK2D: 1.54-fold Up; FDR = 4.06e-08; PValue = 2.07e-09; mean CPM = 51.52; calcium/calmodulin-dependent protein kinase II delta" ID="ID_335929490" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMO: 2.06-fold Down; FDR = 6.29e-08; PValue = 3.36e-09; mean CPM = 12.79; smoothened homolog (Drosophila)" ID="ID_1464634356" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ESR1: 5.04-fold Up; FDR = 6.62e-08; PValue = 3.55e-09; mean CPM = 2.845; estrogen receptor 1" ID="ID_1900490177" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LUM: 1.85-fold Down; FDR = 7.17e-08; PValue = 3.87e-09; mean CPM = 205.3; lumican" ID="ID_308805263" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ANK2: 2.5-fold Up; FDR = 1.44e-07; PValue = 8.35e-09; mean CPM = 31.84; Uncharacterized protein" ID="ID_1139382973" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SDC4: 1.79-fold Up; FDR = 1.95e-07; PValue = 1.16e-08; mean CPM = 109.0; syndecan 4" ID="ID_1615533398" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_615451483" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_549678232" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ANK3: 1.76-fold Down; FDR = 1.13e-06; PValue = 8.29e-08; mean CPM = 81.89; ankyrin 3, node of Ranvier (ankyrin G)" ID="ID_968791896" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FLNB: 1.64-fold Down; FDR = 1.25e-06; PValue = 9.2e-08; mean CPM = 1975; filamin B, beta" ID="ID_279487751" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_653030297" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_1456656184" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THBS1: 2.74-fold Down; FDR = 1.68e-06; PValue = 1.28e-07; mean CPM = 25785; thrombospondin 1" ID="ID_1448817387" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD7: 1.62-fold Down; FDR = 5.66e-06; PValue = 4.95e-07; mean CPM = 34.19; frizzled homolog 7 (Drosophila)" ID="ID_1475185562" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1: 5.76-fold Down; FDR = 6.73e-06; PValue = 6.04e-07; mean CPM = 1.536; insulin-like growth factor 1 (somatomedin C)" ID="ID_429688652" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FLNC: 1.74-fold Down; FDR = 7.81e-06; PValue = 7.15e-07; mean CPM = 868.2; filamin C, gamma" ID="ID_1334688565" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1R: 1.51-fold Down; FDR = 1.02e-05; PValue = 9.61e-07; mean CPM = 213.2; insulin-like growth factor 1 receptor" ID="ID_1846791077" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_812410786" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT5A: 1.65-fold Down; FDR = 2.5e-05; PValue = 2.59e-06; mean CPM = 136.4; wingless-type MMTV integration site family, member 5A" ID="ID_1586982200" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SDC1: 2.19-fold Down; FDR = 2.55e-05; PValue = 2.66e-06; mean CPM = 12.60; syndecan 1" ID="ID_1740484566" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB2: 1.38-fold Down; FDR = 4.66e-05; PValue = 5.24e-06; mean CPM = 61.90; ribosomal protein S6 kinase, 70kDa, polypeptide 2" ID="ID_59356383" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCE1: 3.26-fold Down; FDR = 6.36e-05; PValue = 7.45e-06; mean CPM = 11.49; phospholipase C, epsilon 1" ID="ID_1197855601" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDCD4: 1.38-fold Up; FDR = 0.000119; PValue = 1.5e-05; mean CPM = 39.33; programmed cell death 4 (neoplastic transformation inhibitor)" ID="ID_672504239" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACA: 1.36-fold Down; FDR = 0.000167; PValue = 2.22e-05; mean CPM = 37.75; protein kinase, cAMP-dependent, catalytic, alpha" ID="ID_707391338" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VEGFA: 1.47-fold Up; FDR = 0.000317; PValue = 4.59e-05; mean CPM = 463.7; vascular endothelial growth factor A" ID="ID_1882844412" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HGF: 1.85-fold Down; FDR = 0.000377; PValue = 5.58e-05; mean CPM = 137.4; hepatocyte growth factor (hepapoietin A; scatter factor)" ID="ID_1161016779" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD9: 2.74-fold Down; FDR = 0.000408; PValue = 6.1e-05; mean CPM = 1.789; frizzled homolog 9 (Drosophila)" ID="ID_1526140673" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT1: 7.1-fold Down; FDR = 0.000659; PValue = 0.000105; mean CPM = 2.664; wingless-type MMTV integration site family, member 1" ID="ID_767923641" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EZR: 1.32-fold Up; FDR = 0.00112; PValue = 0.000192; mean CPM = 426.3; Uncharacterized protein" ID="ID_351746522" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTOR: 1.3-fold Down; FDR = 0.00117; PValue = 0.000201; mean CPM = 107.5; mechanistic target of rapamycin (serine/threonine kinase)" ID="ID_1568374855" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAMK2A: 2.29-fold Down; FDR = 0.00124; PValue = 0.000217; mean CPM = 2.001; calcium/calmodulin-dependent protein kinase II alpha" ID="ID_535465790" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP9: 4.49-fold Down; FDR = 0.00222; PValue = 0.000419; mean CPM = 6.597; matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)" ID="ID_785512069" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD4: 1.83-fold Up; FDR = 0.00258; PValue = 0.000495; mean CPM = 4.537; frizzled homolog 4 (Drosophila)" ID="ID_1422690667" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHOA: 1.28-fold Down; FDR = 0.00295; PValue = 0.000575; mean CPM = 277.8; ras homolog gene family, member A" ID="ID_736338426" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARHGEF1: 1.3-fold Down; FDR = 0.00297; PValue = 0.000581; mean CPM = 51.91; Rho guanine nucleotide exchange factor (GEF) 1" ID="ID_615903300" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKX: 1.31-fold Down; FDR = 0.00331; PValue = 0.000658; mean CPM = 24.94; protein kinase, X-linked" ID="ID_181412257" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG1: 1.31-fold Down; FDR = 0.00352; PValue = 0.000707; mean CPM = 53.66; phospholipase C, gamma 1" ID="ID_345903090" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP1R12B: 1.52-fold Down; FDR = 0.00383; PValue = 0.000782; mean CPM = 15.41; protein phosphatase 1, regulatory (inhibitor) subunit 12B" ID="ID_1274139342" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CBLC: 2.87-fold Down; FDR = 0.00443; PValue = 0.000923; mean CPM = 3.105; Cas-Br-M (murine) ecotropic retroviral transforming sequence c" ID="ID_1322374971" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAMK2B: 3.82-fold Down; FDR = 0.00536; PValue = 0.00115; mean CPM = 1.542; calcium/calmodulin-dependent protein kinase II beta" ID="ID_1724141226" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MDM2: 1.32-fold Up; FDR = 0.00555; PValue = 0.00119; mean CPM = 148.6; Uncharacterized protein" ID="ID_548156713" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAV1: 1.33-fold Down; FDR = 0.00575; PValue = 0.00125; mean CPM = 228.7; caveolin-1" ID="ID_774428763" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT7A: 3.46-fold Down; FDR = 0.00638; PValue = 0.0014; mean CPM = 1.036; wingless-type MMTV integration site family, member 7A" ID="ID_1912050442" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF12: 1.26-fold Up; FDR = 0.00782; PValue = 0.00177; mean CPM = 34.71; fibroblast growth factor 12" ID="ID_1755100390" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT10A: 4.08-fold Down; FDR = 0.00805; PValue = 0.00183; mean CPM = 0.9138; wingless-type MMTV integration site family, member 10A" ID="ID_1344912871" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT5B: 1.58-fold Down; FDR = 0.00866; PValue = 0.002; mean CPM = 7.832; wingless-type MMTV integration site family, member 5B" ID="ID_1499141254" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TFAP4: 1.41-fold Up; FDR = 0.00995; PValue = 0.00234; mean CPM = 8.100; transcription factor AP-4 (activating enhancer binding protein 4)" ID="ID_198146106" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT10B: 3.1-fold Down; FDR = 0.0148; PValue = 0.00369; mean CPM = 1.086; wingless-type MMTV integration site family, member 10B" ID="ID_473071283" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FN1: 1.7-fold Down; FDR = 0.0164; PValue = 0.00417; mean CPM = 40317; fibronectin 1" ID="ID_1742602611" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1390165199" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1356173559" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF21: 1.97-fold Up; FDR = 0.0263; PValue = 0.00722; mean CPM = 56.49; fibroblast growth factor 21" ID="ID_579471718" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RRAS2: 1.21-fold Up; FDR = 0.0278; PValue = 0.00771; mean CPM = 61.00; related RAS viral (r-ras) oncogene homolog 2" ID="ID_1373557374" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARHGEF12: 1.21-fold Up; FDR = 0.0298; PValue = 0.00837; mean CPM = 203.3; Rho guanine nucleotide exchange factor (GEF) 12" ID="ID_1232311014" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KDR: 2.01-fold Up; FDR = 0.0328; PValue = 0.00936; mean CPM = 2.053; kinase insert domain receptor (a type III receptor tyrosine kinase)" ID="ID_1045389103" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD2: 1.2-fold Up; FDR = 0.034; PValue = 0.00976; mean CPM = 57.10; SMAD family member 2" ID="ID_786814830" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDPK1: 1.24-fold Down; FDR = 0.0361; PValue = 0.0105; mean CPM = 17.53; 3-phosphoinositide dependent protein kinase-1" ID="ID_460708638" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KRAS: 1.35-fold Down; FDR = 0.0401; PValue = 0.0119; mean CPM = 13.10; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog" ID="ID_106114649" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTNNB1: 1.2-fold Up; FDR = 0.0498; PValue = 0.0153; mean CPM = 558.3; catenin (cadherin-associated protein), beta 1, 88kDa" ID="ID_409336525" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT4: 1.52-fold Down; FDR = 0.0525; PValue = 0.0163; mean CPM = 13.66; wingless-type MMTV integration site family, member 4" ID="ID_1334886718" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NRAS: 1.2-fold Down; FDR = 0.0546; PValue = 0.017; mean CPM = 32.39; neuroblastoma RAS viral (v-ras) oncogene homolog" ID="ID_461452906" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_1521806464" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_652129709" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TIAM1: 1.23-fold Up; FDR = 0.0747; PValue = 0.0248; mean CPM = 38.38; T-cell lymphoma invasion and metastasis 1" ID="ID_1991293979" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB1: 1.23-fold Up; FDR = 0.0759; PValue = 0.0253; mean CPM = 2700; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)" ID="ID_359124832" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GPC3: 2.08-fold Down; FDR = 0.0835; PValue = 0.0283; mean CPM = 1.160; glypican 3" ID="ID_569498955" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF11: 1.44-fold Down; FDR = 0.0841; PValue = 0.0285; mean CPM = 3.869; fibroblast growth factor 11" ID="ID_943298864" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITPR2: 1.17-fold Up; FDR = 0.0872; PValue = 0.0297; mean CPM = 69.62; inositol 1,4,5-trisphosphate receptor, type 2" ID="ID_1690136305" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS2: 1.17-fold Up; FDR = 0.1; PValue = 0.0353; mean CPM = 31.79; son of sevenless homolog 2 (Drosophila)" ID="ID_552406796" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FRS2: 1.17-fold Up; FDR = 0.105; PValue = 0.0373; mean CPM = 37.92; fibroblast growth factor receptor substrate 2" ID="ID_1078026404" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HPSE: 1.22-fold Up; FDR = 0.105; PValue = 0.0374; mean CPM = 14.85; heparanase" ID="ID_1607398647" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND1: 1.17-fold Up; FDR = 0.121; PValue = 0.0443; mean CPM = 867.3; cyclin D1" ID="ID_147395457" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC9A1: 1.19-fold Up; FDR = 0.126; PValue = 0.0463; mean CPM = 29.32; solute carrier family 9 (sodium/hydrogen exchanger), member 1" ID="ID_430156499" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGFR1: 1.15-fold Down; FDR = 0.139; PValue = 0.0525; mean CPM = 89.41; fibroblast growth factor receptor 1" ID="ID_338262001" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD1: 1.23-fold Down; FDR = 0.154; PValue = 0.0592; mean CPM = 31.65; frizzled homolog 1 (Drosophila)" ID="ID_196403006" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ROCK2: 1.14-fold Up; FDR = 0.166; PValue = 0.065; mean CPM = 247.7; Rho-associated, coiled-coil containing protein kinase 2" ID="ID_1669396661" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP1R12A: 1.14-fold Up; FDR = 0.167; PValue = 0.0655; mean CPM = 282.7; protein phosphatase 1, regulatory (inhibitor) subunit 12A" ID="ID_495676853" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RDX: 1.14-fold Up; FDR = 0.168; PValue = 0.066; mean CPM = 58.63; radixin" ID="ID_152445138" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF23: 2.01-fold Down; FDR = 0.188; PValue = 0.0759; mean CPM = 0.9718; fibroblast growth factor 23" ID="ID_1319802901" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ERBB4: 2.18-fold Up; FDR = 0.193; PValue = 0.0786; mean CPM = 0.8876; v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)" ID="ID_1377084442" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITPR3: 1.13-fold Up; FDR = 0.194; PValue = 0.079; mean CPM = 157.4; inositol 1,4,5-triphosphate receptor, type 3" ID="ID_1703417174" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1417782960" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLAUR: 1.19-fold Down; FDR = 0.199; PValue = 0.0819; mean CPM = 46.31; Uncharacterized protein" ID="ID_1426018385" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT3A: 2.28-fold Down; FDR = 0.2; PValue = 0.0823; mean CPM = 0.8811; wingless-type MMTV integration site family, member 3A" ID="ID_740031354" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BRAF: 1.14-fold Down; FDR = 0.228; PValue = 0.0964; mean CPM = 24.98; v-raf murine sarcoma viral oncogene homolog B1" ID="ID_1000932601" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ERBB2: 1.14-fold Down; FDR = 0.23; PValue = 0.0977; mean CPM = 119.0; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)" ID="ID_114373436" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TWIST1: 1.18-fold Up; FDR = 0.24; PValue = 0.103; mean CPM = 10.19; Twist-like protein; Uncharacterized protein" ID="ID_18347774" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAV2: 1.14-fold Down; FDR = 0.24; PValue = 0.103; mean CPM = 25.69; caveolin 2" ID="ID_317737865" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF10: 1.55-fold Down; FDR = 0.257; PValue = 0.112; mean CPM = 3.488; fibroblast growth factor 10" ID="ID_406300955" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1A: 1.16-fold Down; FDR = 0.28; PValue = 0.124; mean CPM = 363.2; Cyclin-dependent kinase inhibitor 1; Uncharacterized protein" ID="ID_1320850270" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_415332340" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT3: 1.4-fold Up; FDR = 0.304; PValue = 0.138; mean CPM = 1.843; wingless-type MMTV integration site family, member 3" ID="ID_986072279" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTTN: 1.12-fold Down; FDR = 0.304; PValue = 0.138; mean CPM = 500.4; cortactin" ID="ID_1433594285" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ANK1: 1.26-fold Up; FDR = 0.319; PValue = 0.146; mean CPM = 6.857; ankyrin 1, erythrocytic" ID="ID_1131394136" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTCH1: 1.14-fold Down; FDR = 0.32; PValue = 0.147; mean CPM = 13.18; patched homolog 1 (Drosophila)" ID="ID_1329054447" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_743787996" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD6: 1.11-fold Down; FDR = 0.347; PValue = 0.162; mean CPM = 39.10; frizzled homolog 6 (Drosophila)" ID="ID_480436522" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP53: 1.11-fold Down; FDR = 0.364; PValue = 0.172; mean CPM = 33.25; tumor protein p53" ID="ID_1055519622" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF2: 1.42-fold Up; FDR = 0.383; PValue = 0.183; mean CPM = 31.20; insulin-like growth factor 2 (somatomedin A)" ID="ID_913692927" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1591556889" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2: 1.1-fold Up; FDR = 0.394; PValue = 0.191; mean CPM = 102.5; PTK2 protein tyrosine kinase 2" ID="ID_1602681432" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD5: 1.34-fold Down; FDR = 0.405; PValue = 0.197; mean CPM = 2.107; frizzled homolog 5 (Drosophila)" ID="ID_547444589" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_457704375" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RNASEN: 1.09-fold Down; FDR = 0.413; PValue = 0.202; mean CPM = 65.43; ribonuclease type III, nuclear" ID="ID_1090818847" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RRAS: 1.1-fold Up; FDR = 0.415; PValue = 0.203; mean CPM = 223.0; related RAS viral (r-ras) oncogene homolog" ID="ID_1904006118" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_254633672" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK12: 1.19-fold Down; FDR = 0.422; PValue = 0.208; mean CPM = 6.569; mitogen-activated protein kinase 12" ID="ID_1048639420" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HOXD10: 1.48-fold Down; FDR = 0.435; PValue = 0.216; mean CPM = 1.820; homeobox D10" ID="ID_1749790507" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1009693033" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_310632189" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT9A: 1.43-fold Down; FDR = 0.505; PValue = 0.262; mean CPM = 2.172; wingless-type MMTV integration site family, member 9A" ID="ID_1722806093" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_1520829417" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK13: 1.22-fold Down; FDR = 0.536; PValue = 0.284; mean CPM = 3.100; mitogen-activated protein kinase 13" ID="ID_470663664" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF18: 1.55-fold Down; FDR = 0.548; PValue = 0.293; mean CPM = 0.9359; fibroblast growth factor 18" ID="ID_1903108017" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP1CB: 1.08-fold Up; FDR = 0.566; PValue = 0.306; mean CPM = 108.6; protein phosphatase 1, catalytic subunit, beta isozyme" ID="ID_1456055154" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6: 1.08-fold Up; FDR = 0.584; PValue = 0.318; mean CPM = 892.5; ribosomal protein S6" ID="ID_50328665" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDC42: 1.07-fold Down; FDR = 0.608; PValue = 0.335; mean CPM = 91.67; cell division cycle 42" ID="ID_488371781" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCG: 1.47-fold Down; FDR = 0.609; PValue = 0.336; mean CPM = 0.9297; protein kinase C, gamma" ID="ID_862879095" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT2B: 1.29-fold Down; FDR = 0.621; PValue = 0.345; mean CPM = 1.575; wingless-type MMTV integration site family, member 2B" ID="ID_1024421317" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GAB1: 1.1-fold Up; FDR = 0.635; PValue = 0.356; mean CPM = 14.59; GRB2-associated binding protein 1" ID="ID_1681633487" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF5: 1.1-fold Down; FDR = 0.646; PValue = 0.364; mean CPM = 54.02; fibroblast growth factor 5" ID="ID_852148419" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DDX5: 1.07-fold Up; FDR = 0.662; PValue = 0.377; mean CPM = 756.3; DEAD (Asp-Glu-Ala-Asp) box polypeptide 5" ID="ID_1944309155" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VTN: 1.19-fold Up; FDR = 0.669; PValue = 0.382; mean CPM = 2.950; vitronectin" ID="ID_178945239" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCB: 1.86-fold Up; FDR = 0.727; PValue = 0.43; mean CPM = 0.8705; protein kinase C, beta" ID="ID_353747988" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF9: 1.77-fold Up; FDR = 0.74; PValue = 0.441; mean CPM = 0.8485; fibroblast growth factor 9 (glia-activating factor)" ID="ID_1718597839" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HCLS1: 1.11-fold Up; FDR = 0.749; PValue = 0.449; mean CPM = 12.24; Hematopoietic lineage cell-specific protein; Uncharacterized protein" ID="ID_1964285245" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_631612737" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF8: 1.75-fold Down; FDR = 0.783; PValue = 0.48; mean CPM = 0.8245; Uncharacterized protein" ID="ID_1518997674" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACG: 1.51-fold Down; FDR = 0.795; PValue = 0.491; mean CPM = 0.8026; protein kinase, cAMP-dependent, catalytic, gamma" ID="ID_77970420" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF14: 1.13-fold Down; FDR = 0.809; PValue = 0.505; mean CPM = 6.007; fibroblast growth factor 14" ID="ID_1178248465" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CBL: 1.05-fold Down; FDR = 0.824; PValue = 0.524; mean CPM = 51.06; Cas-Br-M (murine) ecotropic retroviral transforming sequence" ID="ID_47118665" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT16: 1.27-fold Down; FDR = 0.857; PValue = 0.571; mean CPM = 0.9003; wingless-type MMTV integration site family, member 16" ID="ID_400302125" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CBLB: 1.04-fold Down; FDR = 0.859; PValue = 0.574; mean CPM = 64.59; Cas-Br-M (murine) ecotropic retroviral transforming sequence b" ID="ID_1921042079" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD63: 1.04-fold Down; FDR = 0.873; PValue = 0.591; mean CPM = 935.5; CD63 molecule" ID="ID_918957284" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_741536045" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB1: 1.04-fold Up; FDR = 0.88; PValue = 0.6; mean CPM = 30.80; Uncharacterized protein" ID="ID_124896981" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF13: 1.24-fold Up; FDR = 0.882; PValue = 0.602; mean CPM = 1.024; Fibroblast growth factor 13 isoform 1; Uncharacterized protein" ID="ID_1231314548" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_1798188993" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF3: 1.22-fold Down; FDR = 0.903; PValue = 0.641; mean CPM = 0.7938; fibroblast growth factor 3 (murine mammary tumor virus integration site (v-int-2) oncogene homolog)" ID="ID_905285135" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT11: 1.18-fold Up; FDR = 0.903; PValue = 0.641; mean CPM = 1.340; wingless-type MMTV integration site family, member 11" ID="ID_744307992" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB2: 1.05-fold Down; FDR = 0.903; PValue = 0.655; mean CPM = 110.8; transforming growth factor, beta 2" ID="ID_1596983370" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF17: 1.34-fold Down; FDR = 0.903; PValue = 0.662; mean CPM = 0.8230; fibroblast growth factor 17" ID="ID_1481978736" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000021684: 1.44-fold Up; FDR = 0.903; PValue = 0.662; mean CPM = 0.8513; Uncharacterized protein" ID="ID_1525318012" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACB: 1.03-fold Up; FDR = 0.911; PValue = 0.694; mean CPM = 30.10; protein kinase, cAMP-dependent, catalytic, beta" ID="ID_1373892973" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IQGAP1: 1.03-fold Down; FDR = 0.911; PValue = 0.7; mean CPM = 702.2; IQ motif containing GTPase activating protein 1" ID="ID_1307763658" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK1: 1.03-fold Down; FDR = 0.911; PValue = 0.705; mean CPM = 18.65; p21 protein (Cdc42/Rac)-activated kinase 1" ID="ID_1724310792" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF19: 1.33-fold Down; FDR = 0.921; PValue = 0.724; mean CPM = 0.8101; fibroblast growth factor 19" ID="ID_1259602842" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB1: 1.02-fold Down; FDR = 0.936; PValue = 0.749; mean CPM = 62.61; transforming growth factor, beta 1" ID="ID_1184986154" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FASLG: 1.2-fold Down; FDR = 0.941; PValue = 0.757; mean CPM = 0.8088; Fas ligand (TNF superfamily, member 6)" ID="ID_1913595551" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_1845603484" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF6: 1.15-fold Up; FDR = 0.948; PValue = 0.773; mean CPM = 0.8082; fibroblast growth factor 6" ID="ID_1220583918" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DCN: 1.03-fold Up; FDR = 0.959; PValue = 0.792; mean CPM = 773.4; decorin" ID="ID_1480195983" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_424137050" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12B: 1.07-fold Up; FDR = 0.983; PValue = 0.831; mean CPM = 0.8197; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)" ID="ID_1388349969" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG2: 1.06-fold Up; FDR = 0.985; PValue = 0.834; mean CPM = 2.248; phospholipase C, gamma 2 (phosphatidylinositol-specific)" ID="ID_402321608" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT8B: 1.21-fold Down; FDR = 0.987; PValue = 0.838; mean CPM = 0.8506; wingless-type MMTV integration site family, member 8B" ID="ID_419839451" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ERBB3: 1.05-fold Up; FDR = 0.999; PValue = 0.856; mean CPM = 1.467; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)" ID="ID_608081894" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT2: 1.07-fold Down; FDR = 1; PValue = 0.888; mean CPM = 0.8103; wingless-type MMTV integration site family member 2" ID="ID_82619664" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPB2: 1.05-fold Down; FDR = 1; PValue = 0.889; mean CPM = 0.9668; heat shock 27kDa protein 2" ID="ID_469936460" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD3: 1.03-fold Up; FDR = 1; PValue = 0.903; mean CPM = 1.636; frizzled homolog 3 (Drosophila)" ID="ID_450498460" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL21A1: 1.03-fold Down; FDR = 1; PValue = 0.904; mean CPM = 1.650; collagen, type XXI, alpha 1" ID="ID_604870562" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD10: 1.04-fold Down; FDR = 1; PValue = 0.919; mean CPM = 0.8435; frizzled homolog 10 (Drosophila)" ID="ID_530799126" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT6: 1.13-fold Down; FDR = 1; PValue = 0.956; mean CPM = 0.8230; wingless-type MMTV integration site family, member 6" ID="ID_238378525" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV2: No Change; FDR = 1; PValue = 0.976; mean CPM = 25.65; vav 2 guanine nucleotide exchange factor" ID="ID_1528968197" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP2: No Change; FDR = 1; PValue = 0.976; mean CPM = 210.3; matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)" ID="ID_1049105696" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAV3: 1.02-fold Down; FDR = 1; PValue = 0.98; mean CPM = 0.7970; caveolin 3" ID="ID_1991495336" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD44: No Change; FDR = 1; PValue = 0.981; mean CPM = 487.7; CD44 molecule (Indian blood group)" ID="ID_298160295" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT9B: 1.03-fold Up; FDR = 1; PValue = 0.991; mean CPM = 0.8041; wingless-type MMTV integration site family, member 9B" ID="ID_1899025783" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF20: No Change; FDR = 1; PValue = 1; mean CPM = 0.7796; fibroblast growth factor 20" ID="ID_1860639610" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Thyroid hormone signaling pathway: Inhibited, FDR = 0.0532, FWER = 1, PValue = 0.0117" ID="ID_708966052" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_42045705" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCOA2: 1.84-fold Up; FDR = 6.82e-14; PValue = 8.49e-16; mean CPM = 56.22; nuclear receptor coactivator 2" ID="ID_500112418" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOTCH3: 6.31-fold Down; FDR = 2.33e-13; PValue = 3.29e-15; mean CPM = 185.7; Notch homolog 3 (Drosophila)" ID="ID_433747788" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP1A2: 12.5-fold Down; FDR = 4.89e-13; PValue = 7.44e-15; mean CPM = 10.52; ATPase, Na+/K+ transporting, alpha 2 polypeptide" ID="ID_502654131" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MED17: 1.73-fold Up; FDR = 6.46e-13; PValue = 1.01e-14; mean CPM = 74.90; mediator complex subunit 17" ID="ID_1062744734" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAV: 2.64-fold Down; FDR = 6.04e-11; PValue = 1.51e-12; mean CPM = 337.3; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)" ID="ID_1529481413" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP1B1: 2.02-fold Down; FDR = 1.14e-10; PValue = 3.02e-12; mean CPM = 121.2; Sodium/potassium-transporting ATPase subunit beta-1; Uncharacterized protein" ID="ID_147072849" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB3: 5.02-fold Down; FDR = 1.72e-09; PValue = 6.17e-11; mean CPM = 43.21; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)" ID="ID_846012379" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCD3: 1.96-fold Down; FDR = 1.98e-08; PValue = 9.29e-10; mean CPM = 26.23; phospholipase C, delta 3" ID="ID_165674791" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ESR1: 5.04-fold Up; FDR = 6.62e-08; PValue = 3.55e-09; mean CPM = 2.845; estrogen receptor 1" ID="ID_403896721" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_401341597" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCB1: 1.71-fold Up; FDR = 1.31e-06; PValue = 9.73e-08; mean CPM = 34.36; phospholipase C, beta 1 (phosphoinositide-specific)" ID="ID_1419900977" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1535521430" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_1884996724" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MED16: 1.5-fold Down; FDR = 1.56e-06; PValue = 1.18e-07; mean CPM = 66.70; mediator complex subunit 16" ID="ID_684602540" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TSC2: 1.44-fold Down; FDR = 1e-05; PValue = 9.42e-07; mean CPM = 124.0; tuberous sclerosis 2" ID="ID_701852025" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_918628305" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MED30: 1.47-fold Up; FDR = 1.75e-05; PValue = 1.76e-06; mean CPM = 22.85; mediator complex subunit 30" ID="ID_996668870" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCE1: 3.26-fold Down; FDR = 6.36e-05; PValue = 7.45e-06; mean CPM = 11.49; phospholipase C, epsilon 1" ID="ID_1149972" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACA: 1.36-fold Down; FDR = 0.000167; PValue = 2.22e-05; mean CPM = 37.75; protein kinase, cAMP-dependent, catalytic, alpha" ID="ID_1779993601" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCB4: 1.75-fold Down; FDR = 0.00025; PValue = 3.52e-05; mean CPM = 6.730; phospholipase C, beta 4" ID="ID_920516244" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SIN3A: 1.33-fold Up; FDR = 0.000459; PValue = 6.96e-05; mean CPM = 56.62; SIN3 homolog A, transcription regulator (yeast)" ID="ID_695893064" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAD: 1.36-fold Down; FDR = 0.000605; PValue = 9.52e-05; mean CPM = 48.46; BCL2-associated agonist of cell death" ID="ID_922319640" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PFKFB2: 1.68-fold Down; FDR = 0.000865; PValue = 0.000143; mean CPM = 5.864; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2" ID="ID_1344085935" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOXO1: 1.49-fold Down; FDR = 0.00109; PValue = 0.000186; mean CPM = 11.95; forkhead box O1" ID="ID_986479811" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTOR: 1.3-fold Down; FDR = 0.00117; PValue = 0.000201; mean CPM = 107.5; mechanistic target of rapamycin (serine/threonine kinase)" ID="ID_1856822064" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOTCH1: 1.44-fold Down; FDR = 0.0032; PValue = 0.000634; mean CPM = 32.99; Notch homolog 1, translocation-associated (Drosophila)" ID="ID_235874687" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKX: 1.31-fold Down; FDR = 0.00331; PValue = 0.000658; mean CPM = 24.94; protein kinase, X-linked" ID="ID_614517146" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG1: 1.31-fold Down; FDR = 0.00352; PValue = 0.000707; mean CPM = 53.66; phospholipase C, gamma 1" ID="ID_1101431656" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MDM2: 1.32-fold Up; FDR = 0.00555; PValue = 0.00119; mean CPM = 148.6; Uncharacterized protein" ID="ID_1619952013" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCOA3: 1.24-fold Up; FDR = 0.0123; PValue = 0.00297; mean CPM = 178.3; nuclear receptor coactivator 3" ID="ID_1441345655" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MED4: 1.26-fold Up; FDR = 0.0124; PValue = 0.003; mean CPM = 28.63; mediator complex subunit 4" ID="ID_1890085727" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AC144536.2: 1.23-fold Down; FDR = 0.014; PValue = 0.00346; mean CPM = 58.91; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1 isoform 1" ID="ID_1482912492" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC1: 1.25-fold Up; FDR = 0.0159; PValue = 0.00403; mean CPM = 27.51; histone deacetylase 1" ID="ID_62900800" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_688534538" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1882973349" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP1A1: 1.22-fold Down; FDR = 0.0272; PValue = 0.00752; mean CPM = 361.3; ATPase, Na+/K+ transporting, alpha 1 polypeptide" ID="ID_988002005" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RCAN1: 1.24-fold Down; FDR = 0.0277; PValue = 0.00769; mean CPM = 151.2; regulator of calcineurin 1" ID="ID_205767067" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDPK1: 1.24-fold Down; FDR = 0.0361; PValue = 0.0105; mean CPM = 17.53; 3-phosphoinositide dependent protein kinase-1" ID="ID_1009934766" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KRAS: 1.35-fold Down; FDR = 0.0401; PValue = 0.0119; mean CPM = 13.10; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog" ID="ID_1198007115" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCB2: 3.68-fold Down; FDR = 0.0481; PValue = 0.0147; mean CPM = 1.557; Uncharacterized protein" ID="ID_319773616" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTNNB1: 1.2-fold Up; FDR = 0.0498; PValue = 0.0153; mean CPM = 558.3; catenin (cadherin-associated protein), beta 1, 88kDa" ID="ID_1203399316" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT4: 1.52-fold Down; FDR = 0.0525; PValue = 0.0163; mean CPM = 13.66; wingless-type MMTV integration site family, member 4" ID="ID_282658299" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NRAS: 1.2-fold Down; FDR = 0.0546; PValue = 0.017; mean CPM = 32.39; neuroblastoma RAS viral (v-ras) oncogene homolog" ID="ID_412732465" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP1B3: 1.19-fold Down; FDR = 0.0573; PValue = 0.0181; mean CPM = 46.02; ATPase, Na+/K+ transporting, beta 3 polypeptide" ID="ID_927820042" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_652729765" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_1717865335" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP1B3: 1.3-fold Down; FDR = 0.0737; PValue = 0.0244; mean CPM = 6.672; Uncharacterized protein" ID="ID_234710688" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RXRA: 1.18-fold Down; FDR = 0.077; PValue = 0.0257; mean CPM = 35.60; retinoid X receptor, alpha" ID="ID_19896728" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MED13: 1.17-fold Up; FDR = 0.0854; PValue = 0.029; mean CPM = 140.1; mediator complex subunit 13" ID="ID_664288068" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCOA1: 1.18-fold Up; FDR = 0.112; PValue = 0.04; mean CPM = 20.42; nuclear receptor coactivator 1" ID="ID_1888113805" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC2: 1.15-fold Up; FDR = 0.115; PValue = 0.0414; mean CPM = 93.64; histone deacetylase 2" ID="ID_1698075735" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BMP4: 1.86-fold Down; FDR = 0.119; PValue = 0.0432; mean CPM = 2.163; bone morphogenetic protein 4" ID="ID_1007039350" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND1: 1.17-fold Up; FDR = 0.121; PValue = 0.0443; mean CPM = 867.3; cyclin D1" ID="ID_1454771194" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC9A1: 1.19-fold Up; FDR = 0.126; PValue = 0.0463; mean CPM = 29.32; solute carrier family 9 (sodium/hydrogen exchanger), member 1" ID="ID_860480140" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_1541949475" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHEB: 1.13-fold Up; FDR = 0.193; PValue = 0.0785; mean CPM = 118.9; Ras homolog enriched in brain" ID="ID_954653740" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP1A4: 1.92-fold Down; FDR = 0.235; PValue = 0.1; mean CPM = 1.006; ATPase, Na+/K+ transporting, alpha 4 polypeptide" ID="ID_1850887546" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PFKP: 1.12-fold Up; FDR = 0.268; PValue = 0.117; mean CPM = 517.4; phosphofructokinase, platelet" ID="ID_109418253" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_770105665" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EP300: 1.11-fold Up; FDR = 0.312; PValue = 0.142; mean CPM = 162.8; E1A binding protein p300" ID="ID_1035412540" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_597488068" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP53: 1.11-fold Down; FDR = 0.364; PValue = 0.172; mean CPM = 33.25; tumor protein p53" ID="ID_835226137" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000003919: 1.15-fold Down; FDR = 0.369; PValue = 0.175; mean CPM = 68.21; Uncharacterized protein" ID="ID_1552434940" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1540653958" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THRA: 1.12-fold Down; FDR = 0.401; PValue = 0.195; mean CPM = 14.87; thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)" ID="ID_113814147" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_284688826" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOTCH2: 1.09-fold Down; FDR = 0.514; PValue = 0.268; mean CPM = 795.0; Notch homolog 2 (Drosophila)" ID="ID_693741372" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_1574949804" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KAT2A: 1.08-fold Up; FDR = 0.579; PValue = 0.315; mean CPM = 30.51; K(lysine) acetyltransferase 2A" ID="ID_1886039485" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCG: 1.47-fold Down; FDR = 0.609; PValue = 0.336; mean CPM = 0.9297; protein kinase C, gamma" ID="ID_1894278450" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KAT2B: 1.13-fold Up; FDR = 0.663; PValue = 0.378; mean CPM = 11.06; Uncharacterized protein" ID="ID_1259491470" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP2A2: 1.06-fold Down; FDR = 0.705; PValue = 0.411; mean CPM = 361.0; ATPase, Ca++ transporting, cardiac muscle, slow twitch 2" ID="ID_1262533249" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCB: 1.86-fold Up; FDR = 0.727; PValue = 0.43; mean CPM = 0.8705; protein kinase C, beta" ID="ID_340172407" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP1B4: 1.87-fold Up; FDR = 0.756; PValue = 0.455; mean CPM = 0.8457; ATPase, Na+/K+ transporting, beta 4 polypeptide" ID="ID_7556309" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC2A1: 1.06-fold Down; FDR = 0.782; PValue = 0.479; mean CPM = 105.3; solute carrier family 2 (facilitated glucose transporter), member 1" ID="ID_119851827" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACG: 1.51-fold Down; FDR = 0.795; PValue = 0.491; mean CPM = 0.8026; protein kinase, cAMP-dependent, catalytic, gamma" ID="ID_1793888960" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MED13L: 1.05-fold Down; FDR = 0.821; PValue = 0.52; mean CPM = 161.2; mediator complex subunit 13-like" ID="ID_1941869376" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GATA4: 1.31-fold Up; FDR = 0.865; PValue = 0.582; mean CPM = 0.8258; GATA binding protein 4" ID="ID_1554249255" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1736999628" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FXYD2: 1.25-fold Up; FDR = 0.898; PValue = 0.624; mean CPM = 0.7915; FXYD domain containing ion transport regulator 2" ID="ID_16968669" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000021684: 1.44-fold Up; FDR = 0.903; PValue = 0.662; mean CPM = 0.8513; Uncharacterized protein" ID="ID_1945382789" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACB: 1.03-fold Up; FDR = 0.911; PValue = 0.694; mean CPM = 30.10; protein kinase, cAMP-dependent, catalytic, beta" ID="ID_1816249675" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MED1: 1.03-fold Up; FDR = 0.911; PValue = 0.699; mean CPM = 81.93; mediator complex subunit 1" ID="ID_41170804" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RXRG: 1.32-fold Up; FDR = 0.915; PValue = 0.714; mean CPM = 0.8688; retinoid X receptor, gamma" ID="ID_562141114" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_821549257" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYH6: 1.11-fold Up; FDR = 0.975; PValue = 0.817; mean CPM = 1.001; myosin, heavy chain 6, cardiac muscle, alpha" ID="ID_66348330" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG2: 1.06-fold Up; FDR = 0.985; PValue = 0.834; mean CPM = 2.248; phospholipase C, gamma 2 (phosphatidylinositol-specific)" ID="ID_1663232760" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREBBP: 1.01-fold Down; FDR = 0.993; PValue = 0.847; mean CPM = 137.7; CREB binding protein" ID="ID_1128162027" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC3: 1.01-fold Up; FDR = 1; PValue = 0.861; mean CPM = 41.13; histone deacetylase 3" ID="ID_475122767" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP9: 1.01-fold Up; FDR = 1; PValue = 0.908; mean CPM = 19.86; caspase 9, apoptosis-related cysteine peptidase" ID="ID_1253551444" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MED14: 1.01-fold Down; FDR = 1; PValue = 0.916; mean CPM = 56.17; mediator complex subunit 14" ID="ID_98921472" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCZ1: 1.2-fold Down; FDR = 1; PValue = 0.95; mean CPM = 0.8210; phospholipase C, zeta 1" ID="ID_1932133684" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP1B2: 1.12-fold Down; FDR = 1; PValue = 0.958; mean CPM = 0.8232; ATPase, Na+/K+ transporting, beta 2 polypeptide" ID="ID_1529205936" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Toll-like receptor signaling pathway: Activated, FDR = 0.0645, FWER = 1, PValue = 0.0155" ID="ID_239096003" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TLR2: 8.94-fold Up; FDR = 6.97e-23; PValue = 1.25e-25; mean CPM = 18.41; toll-like receptor 2" ID="ID_1016371811" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL10: 462-fold Up; FDR = 1.01e-21; PValue = 2.65e-24; mean CPM = 286.2; Macaca mulatta chemokine (C-X-C motif) ligand 10 (CXCL10), mRNA." ID="ID_1467051053" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR3: 10.3-fold Up; FDR = 1.95e-21; PValue = 5.6e-24; mean CPM = 35.70; toll-like receptor 3" ID="ID_1244986538" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL11: 256-fold Up; FDR = 1e-19; PValue = 3.96e-22; mean CPM = 84.82; chemokine (C-X-C motif) ligand 11" ID="ID_1762359738" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL9: 345-fold Up; FDR = 4.16e-19; PValue = 1.97e-21; mean CPM = 175.7; Macaca mulatta chemokine (C-X-C motif) ligand 9 (CXCL9), mRNA." ID="ID_1482029371" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_8338958" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF7: 14.8-fold Up; FDR = 7.66e-18; PValue = 4.82e-20; mean CPM = 11.54; Macaca mulatta interferon regulatory factor 7 (IRF7), mRNA." ID="ID_356236059" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_517558940" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LY96: 3.13-fold Up; FDR = 1.27e-10; PValue = 3.43e-12; mean CPM = 6.127; lymphocyte antigen 96" ID="ID_1437847472" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR4: 3.45-fold Up; FDR = 3.1e-09; PValue = 1.19e-10; mean CPM = 7.456; Macaca mulatta toll-like receptor 4 (TLR4), mRNA." ID="ID_978747165" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_887069996" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK4: 1.8-fold Up; FDR = 3.31e-08; PValue = 1.64e-09; mean CPM = 12.89; interleukin-1 receptor-associated kinase 4" ID="ID_353436264" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_8209648" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL5: 6.74-fold Up; FDR = 2.65e-07; PValue = 1.64e-08; mean CPM = 30.35; chemokine (C-C motif) ligand 5" ID="ID_1261560753" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_158478475" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD14: 2.75-fold Down; FDR = 6.54e-07; PValue = 4.46e-08; mean CPM = 5.195; CD14 molecule" ID="ID_118339282" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1268713787" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_1747521488" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR2: 1.74-fold Up; FDR = 1.85e-06; PValue = 1.44e-07; mean CPM = 26.05; interferon (alpha, beta and omega) receptor 2" ID="ID_1752430078" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_748481999" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K3: 1.45-fold Down; FDR = 7.01e-06; PValue = 6.34e-07; mean CPM = 180.1; mitogen-activated protein kinase kinase 3" ID="ID_405279195" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_567832495" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPP1: 2.25-fold Down; FDR = 7.74e-05; PValue = 9.29e-06; mean CPM = 35.33; secreted phosphoprotein 1" ID="ID_1821730698" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP2: 1.45-fold Up; FDR = 0.000179; PValue = 2.4e-05; mean CPM = 65.31; TGF-beta activated kinase 1/MAP3K7 binding protein 2" ID="ID_1513145905" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40: 2.76-fold Up; FDR = 0.00039; PValue = 5.79e-05; mean CPM = 9.139; CD40 molecule, TNF receptor superfamily member 5" ID="ID_1626486554" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TOLLIP: 1.36-fold Down; FDR = 0.000551; PValue = 8.57e-05; mean CPM = 28.79; Uncharacterized protein" ID="ID_1860079912" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBK1: 1.3-fold Up; FDR = 0.00337; PValue = 0.000674; mean CPM = 30.46; TANK-binding kinase 1" ID="ID_89811364" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1755736131" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_787100106" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR5: 1.86-fold Down; FDR = 0.00878; PValue = 0.00203; mean CPM = 3.008; toll-like receptor 5" ID="ID_22941261" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12A: 2.09-fold Up; FDR = 0.00924; PValue = 0.00215; mean CPM = 2.872; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)" ID="ID_513342802" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR1: 1.27-fold Up; FDR = 0.0101; PValue = 0.00237; mean CPM = 82.39; Uncharacterized protein" ID="ID_1451217868" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1280713785" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL8: 2.33-fold Up; FDR = 0.0209; PValue = 0.00552; mean CPM = 2326; interleukin 8" ID="ID_645456185" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_661312534" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_679278474" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1190712102" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL3: 2.04-fold Down; FDR = 0.067; PValue = 0.0218; mean CPM = 3.575; chemokine (C-C motif) ligand 3" ID="ID_743975899" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K8: 1.35-fold Down; FDR = 0.0831; PValue = 0.0281; mean CPM = 8.912; mitogen-activated protein kinase kinase kinase 8" ID="ID_175278145" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FADD: 1.18-fold Down; FDR = 0.0936; PValue = 0.0324; mean CPM = 30.89; Uncharacterized protein" ID="ID_160642998" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_1439816545" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_952003229" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_60724869" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_327817247" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_903042908" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP1: 1.12-fold Down; FDR = 0.351; PValue = 0.165; mean CPM = 17.96; TGF-beta activated kinase 1/MAP3K7 binding protein 1" ID="ID_1488873332" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1088622994" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TICAM1: 1.11-fold Down; FDR = 0.398; PValue = 0.192; mean CPM = 26.73; toll-like receptor adaptor molecule 1" ID="ID_135378832" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_510698722" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_654729004" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK12: 1.19-fold Down; FDR = 0.422; PValue = 0.208; mean CPM = 6.569; mitogen-activated protein kinase 12" ID="ID_1057362456" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_836027882" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_1418293093" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK13: 1.22-fold Down; FDR = 0.536; PValue = 0.284; mean CPM = 3.100; mitogen-activated protein kinase 13" ID="ID_617681493" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF3: 1.07-fold Up; FDR = 0.611; PValue = 0.338; mean CPM = 34.56; TNF receptor-associated factor 3" ID="ID_1093543523" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_700553252" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNB1: 1.79-fold Up; FDR = 0.731; PValue = 0.433; mean CPM = 0.8526; interferon, beta 1, fibroblast" ID="ID_150064499" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA6: 1.41-fold Down; FDR = 0.807; PValue = 0.504; mean CPM = 0.8019; interferon, alpha 6" ID="ID_1164360394" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR6: 1.07-fold Down; FDR = 0.84; PValue = 0.546; mean CPM = 7.909; toll-like receptor 6" ID="ID_446487070" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TIRAP: 1.07-fold Up; FDR = 0.841; PValue = 0.548; mean CPM = 8.693; Macaca mulatta toll-interleukin 1 receptor (TIR) domain containing adaptor protein (TIRAP), mRNA." ID="ID_877019619" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF5: 1.06-fold Down; FDR = 0.85; PValue = 0.561; mean CPM = 9.280; interferon regulatory factor 5" ID="ID_805405511" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1719898079" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1338685496" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR7: 1.37-fold Down; FDR = 0.878; PValue = 0.597; mean CPM = 0.8402; toll-like receptor 7" ID="ID_1011248818" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK1: 1.04-fold Down; FDR = 0.885; PValue = 0.606; mean CPM = 41.54; interleukin-1 receptor-associated kinase 1" ID="ID_1256430716" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_392831782" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA13: 1.13-fold Up; FDR = 0.908; PValue = 0.677; mean CPM = 0.7960; interferon, alpha 13" ID="ID_248400099" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA8: 1.13-fold Down; FDR = 0.911; PValue = 0.702; mean CPM = 0.7910; interferon, alpha 8" ID="ID_84104414" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKE: 1.03-fold Up; FDR = 0.929; PValue = 0.737; mean CPM = 21.61; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon" ID="ID_555334641" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA14: 1.22-fold Up; FDR = 0.965; PValue = 0.802; mean CPM = 0.8654; interferon, alpha 14" ID="ID_502347863" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_877369081" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD80: 1.08-fold Up; FDR = 0.971; PValue = 0.812; mean CPM = 1.157; CD80 molecule" ID="ID_659725817" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_1891610825" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA4: 1.28-fold Down; FDR = 0.983; PValue = 0.829; mean CPM = 0.8584; interferon, alpha 4" ID="ID_713730576" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12B: 1.07-fold Up; FDR = 0.983; PValue = 0.831; mean CPM = 0.8197; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)" ID="ID_1878204873" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_1053992176" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR9: 1.01-fold Down; FDR = 1; PValue = 0.859; mean CPM = 21.45; Macaca mulatta toll-like receptor 9 (TLR9), mRNA." ID="ID_1948983636" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR1: 1.02-fold Up; FDR = 1; PValue = 0.945; mean CPM = 1.221; toll-like receptor 1" ID="ID_955306640" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD86: 1.01-fold Down; FDR = 1; PValue = 0.99; mean CPM = 0.8012; CD86 molecule" ID="ID_1489028422" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA1: No Change; FDR = 1; PValue = 0.998; mean CPM = 0.8014; interferon, alpha 1" ID="ID_1337566323" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Viral myocarditis: Activated, FDR = 0.0645, FWER = 1, PValue = 0.0155" ID="ID_304364010" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="ICAM1: 24.6-fold Up; FDR = 2.39e-17; PValue = 1.64e-19; mean CPM = 232.4; intercellular adhesion molecule 1" ID="ID_910063901" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_247717886" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DMD: 2.29-fold Down; FDR = 6.37e-12; PValue = 1.28e-13; mean CPM = 17.66; Uncharacterized protein" ID="ID_1323482504" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BID: 1.66-fold Up; FDR = 5.41e-09; PValue = 2.19e-10; mean CPM = 35.19; BH3 interacting domain death agonist" ID="ID_1567824934" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_981470361" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC3: 1.68-fold Down; FDR = 2.72e-06; PValue = 2.19e-07; mean CPM = 13.98; ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)" ID="ID_365682981" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40: 2.76-fold Up; FDR = 0.00039; PValue = 5.79e-05; mean CPM = 9.139; CD40 molecule, TNF receptor superfamily member 5" ID="ID_129841186" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ABL2: 1.32-fold Down; FDR = 0.00103; PValue = 0.000174; mean CPM = 126.8; c-abl oncogene 2, non-receptor tyrosine kinase" ID="ID_1560339669" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAV1: 1.33-fold Down; FDR = 0.00575; PValue = 0.00125; mean CPM = 228.7; caveolin-1" ID="ID_969605896" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FYN: 1.22-fold Up; FDR = 0.0156; PValue = 0.00393; mean CPM = 92.94; FYN oncogene related to SRC, FGR, YES" ID="ID_1410493200" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB2: 1.55-fold Down; FDR = 0.0187; PValue = 0.00485; mean CPM = 34.87; Integrin beta" ID="ID_1326282095" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC2: 2.96-fold Up; FDR = 0.0309; PValue = 0.00872; mean CPM = 0.9737; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)" ID="ID_1035272647" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DAG1: 1.54-fold Down; FDR = 0.0661; PValue = 0.0214; mean CPM = 3.013; dystroglycan 1 (dystrophin-associated glycoprotein 1)" ID="ID_709829194" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000039103: 1.67-fold Down; FDR = 0.221; PValue = 0.0927; mean CPM = 1.310; Uncharacterized protein" ID="ID_51071205" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ABL1: 1.09-fold Up; FDR = 0.43; PValue = 0.213; mean CPM = 178.0; c-abl oncogene 1, receptor tyrosine kinase" ID="ID_914714670" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_1181072088" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYCS: 1.05-fold Up; FDR = 0.854; PValue = 0.565; mean CPM = 93.43; cytochrome c, somatic" ID="ID_571509979" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000040219: 1.08-fold Up; FDR = 0.86; PValue = 0.575; mean CPM = 8.818; Uncharacterized protein" ID="ID_732909366" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000009289: 1.07-fold Up; FDR = 0.963; PValue = 0.798; mean CPM = 2.536; Uncharacterized protein" ID="ID_164616686" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_972337175" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD80: 1.08-fold Up; FDR = 0.971; PValue = 0.812; mean CPM = 1.157; CD80 molecule" ID="ID_784105165" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP9: 1.01-fold Up; FDR = 1; PValue = 0.908; mean CPM = 19.86; caspase 9, apoptosis-related cysteine peptidase" ID="ID_683877602" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAL: 1.03-fold Up; FDR = 1; PValue = 0.95; mean CPM = 1.035; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)" ID="ID_443078105" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40LG: 1.01-fold Down; FDR = 1; PValue = 0.982; mean CPM = 0.8653; CD40 ligand" ID="ID_1228946452" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD86: 1.01-fold Down; FDR = 1; PValue = 0.99; mean CPM = 0.8012; CD86 molecule" ID="ID_7505054" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Aldosterone-regulated sodium reabsorption: Inhibited, FDR = 0.0645, FWER = 1, PValue = 0.0156" ID="ID_1934286825" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="ATP1A2: 12.5-fold Down; FDR = 4.89e-13; PValue = 7.44e-15; mean CPM = 10.52; ATPase, Na+/K+ transporting, alpha 2 polypeptide" ID="ID_480035729" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP1B1: 2.02-fold Down; FDR = 1.14e-10; PValue = 3.02e-12; mean CPM = 121.2; Sodium/potassium-transporting ATPase subunit beta-1; Uncharacterized protein" ID="ID_234986102" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRS1: 2.78-fold Up; FDR = 7.67e-09; PValue = 3.19e-10; mean CPM = 26.55; Uncharacterized protein" ID="ID_1076358621" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INSR: 1.93-fold Down; FDR = 1.24e-08; PValue = 5.48e-10; mean CPM = 118.3; insulin receptor" ID="ID_585152315" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1299217990" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1222578515" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1: 5.76-fold Down; FDR = 6.73e-06; PValue = 6.04e-07; mean CPM = 1.536; insulin-like growth factor 1 (somatomedin C)" ID="ID_1967745667" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SCNN1A: 1.96-fold Up; FDR = 0.000852; PValue = 0.00014; mean CPM = 3.840; sodium channel, nonvoltage-gated 1 alpha" ID="ID_1523875079" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SGK1: 1.36-fold Down; FDR = 0.0048; PValue = 0.00101; mean CPM = 395.0; Uncharacterized protein" ID="ID_1336899133" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP1A1: 1.22-fold Down; FDR = 0.0272; PValue = 0.00752; mean CPM = 361.3; ATPase, Na+/K+ transporting, alpha 1 polypeptide" ID="ID_988079515" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDPK1: 1.24-fold Down; FDR = 0.0361; PValue = 0.0105; mean CPM = 17.53; 3-phosphoinositide dependent protein kinase-1" ID="ID_896413819" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KRAS: 1.35-fold Down; FDR = 0.0401; PValue = 0.0119; mean CPM = 13.10; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog" ID="ID_546103298" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NEDD4L: 1.73-fold Up; FDR = 0.0418; PValue = 0.0124; mean CPM = 7.370; neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase" ID="ID_1964969849" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP1B3: 1.19-fold Down; FDR = 0.0573; PValue = 0.0181; mean CPM = 46.02; ATPase, Na+/K+ transporting, beta 3 polypeptide" ID="ID_828048412" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP1B3: 1.3-fold Down; FDR = 0.0737; PValue = 0.0244; mean CPM = 6.672; Uncharacterized protein" ID="ID_1052779998" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP1A4: 1.92-fold Down; FDR = 0.235; PValue = 0.1; mean CPM = 1.006; ATPase, Na+/K+ transporting, alpha 4 polypeptide" ID="ID_536364825" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SFN: 1.69-fold Down; FDR = 0.304; PValue = 0.138; mean CPM = 1.084; stratifin" ID="ID_1034323329" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_840083724" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SCNN1B: 1.46-fold Down; FDR = 0.372; PValue = 0.177; mean CPM = 6.472; Uncharacterized protein" ID="ID_1283629340" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_676089476" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_535515229" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KCNJ1: 1.39-fold Up; FDR = 0.626; PValue = 0.349; mean CPM = 1.091; potassium inwardly-rectifying channel, subfamily J, member 1" ID="ID_1026099428" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP1B4: 1.87-fold Up; FDR = 0.756; PValue = 0.455; mean CPM = 0.8457; ATPase, Na+/K+ transporting, beta 4 polypeptide" ID="ID_108219856" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NR3C2: 1.18-fold Down; FDR = 0.825; PValue = 0.524; mean CPM = 2.020; nuclear receptor subfamily 3, group C, member 2" ID="ID_764949218" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SCNN1G: 1.72-fold Up; FDR = 0.852; PValue = 0.563; mean CPM = 0.8473; Uncharacterized protein" ID="ID_458273407" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FXYD2: 1.25-fold Up; FDR = 0.898; PValue = 0.624; mean CPM = 0.7915; FXYD domain containing ion transport regulator 2" ID="ID_1523053705" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP1B2: 1.12-fold Down; FDR = 1; PValue = 0.958; mean CPM = 0.8232; ATPase, Na+/K+ transporting, beta 2 polypeptide" ID="ID_1524722883" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg mTOR signaling pathway: Activated, FDR = 0.0702, FWER = 1, PValue = 0.0174" ID="ID_1566349232" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="IRS1: 2.78-fold Up; FDR = 7.67e-09; PValue = 3.19e-10; mean CPM = 26.55; Uncharacterized protein" ID="ID_1558562688" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_297960971" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1139736743" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_699918526" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKAA2: 1.7-fold Down; FDR = 5.6e-06; PValue = 4.89e-07; mean CPM = 11.23; protein kinase, AMP-activated, alpha 2 catalytic subunit" ID="ID_1220246848" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1: 5.76-fold Down; FDR = 6.73e-06; PValue = 6.04e-07; mean CPM = 1.536; insulin-like growth factor 1 (somatomedin C)" ID="ID_1353249568" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TSC2: 1.44-fold Down; FDR = 1e-05; PValue = 9.42e-07; mean CPM = 124.0; tuberous sclerosis 2" ID="ID_659527633" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPTOR: 1.4-fold Down; FDR = 2.58e-05; PValue = 2.69e-06; mean CPM = 53.57; regulatory associated protein of MTOR, complex 1" ID="ID_282866693" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DDIT4: 1.72-fold Up; FDR = 4.15e-05; PValue = 4.58e-06; mean CPM = 395.1; DNA-damage-inducible transcript 4" ID="ID_907359586" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB2: 1.38-fold Down; FDR = 4.66e-05; PValue = 5.24e-06; mean CPM = 61.90; ribosomal protein S6 kinase, 70kDa, polypeptide 2" ID="ID_844920252" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VEGFA: 1.47-fold Up; FDR = 0.000317; PValue = 4.59e-05; mean CPM = 463.7; vascular endothelial growth factor A" ID="ID_226974207" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKAA1: 1.32-fold Up; FDR = 0.000825; PValue = 0.000135; mean CPM = 40.69; protein kinase, AMP-activated, alpha 1 catalytic subunit" ID="ID_1004350104" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTOR: 1.3-fold Down; FDR = 0.00117; PValue = 0.000201; mean CPM = 107.5; mechanistic target of rapamycin (serine/threonine kinase)" ID="ID_615654157" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1S1: 1.31-fold Down; FDR = 0.00202; PValue = 0.000375; mean CPM = 35.32; AKT1 substrate 1 (proline-rich)" ID="ID_1908083846" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF4E2: 1.3-fold Down; FDR = 0.00249; PValue = 0.000475; mean CPM = 29.85; eukaryotic translation initiation factor 4E family member 2" ID="ID_620184582" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RRAGC: 1.41-fold Up; FDR = 0.00682; PValue = 0.00151; mean CPM = 23.61; Ras-related GTP binding C" ID="ID_971846170" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ULK1: 1.34-fold Down; FDR = 0.0121; PValue = 0.00293; mean CPM = 33.52; unc-51-like kinase 1 (C. elegans)" ID="ID_1810217230" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RRAGB: 1.51-fold Up; FDR = 0.0138; PValue = 0.00342; mean CPM = 5.205; Ras-related GTP binding B" ID="ID_922967469" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ULK2: 1.22-fold Up; FDR = 0.0181; PValue = 0.00467; mean CPM = 113.0; unc-51-like kinase 2 (C. elegans)" ID="ID_734767759" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_14956243" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA1: 1.25-fold Down; FDR = 0.0241; PValue = 0.00652; mean CPM = 21.28; ribosomal protein S6 kinase, 90kDa, polypeptide 1" ID="ID_516354172" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_363821826" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDPK1: 1.24-fold Down; FDR = 0.0361; PValue = 0.0105; mean CPM = 17.53; 3-phosphoinositide dependent protein kinase-1" ID="ID_1626433588" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TSC1: 1.19-fold Down; FDR = 0.0564; PValue = 0.0177; mean CPM = 38.34; tuberous sclerosis 1" ID="ID_87586334" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF4EBP1: 1.23-fold Up; FDR = 0.0729; PValue = 0.0241; mean CPM = 40.55; eukaryotic translation initiation factor 4E binding protein 1" ID="ID_930407612" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RRAGA: 1.17-fold Up; FDR = 0.0754; PValue = 0.0251; mean CPM = 149.2; Ras-related GTP binding A" ID="ID_1993061212" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_746350610" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTEN: 1.14-fold Up; FDR = 0.166; PValue = 0.065; mean CPM = 89.60; phosphatase and tensin homolog" ID="ID_1910349590" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHEB: 1.13-fold Up; FDR = 0.193; PValue = 0.0785; mean CPM = 118.9; Ras homolog enriched in brain" ID="ID_691304105" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BRAF: 1.14-fold Down; FDR = 0.228; PValue = 0.0964; mean CPM = 24.98; v-raf murine sarcoma viral oncogene homolog B1" ID="ID_1787758728" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_1439366401" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_1731465558" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_42382975" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_955526973" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RRAGD: 1.48-fold Down; FDR = 0.48; PValue = 0.245; mean CPM = 1.571; Ras-related GTP binding D" ID="ID_337834266" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_856244095" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6: 1.08-fold Up; FDR = 0.584; PValue = 0.318; mean CPM = 892.5; ribosomal protein S6" ID="ID_724923729" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCG: 1.47-fold Down; FDR = 0.609; PValue = 0.336; mean CPM = 0.9297; protein kinase C, gamma" ID="ID_1797677962" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCB: 1.86-fold Up; FDR = 0.727; PValue = 0.43; mean CPM = 0.8705; protein kinase C, beta" ID="ID_542668846" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB1: 1.04-fold Up; FDR = 0.88; PValue = 0.6; mean CPM = 30.80; Uncharacterized protein" ID="ID_1434266762" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_1490081309" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA6: 1.05-fold Down; FDR = 0.941; PValue = 0.758; mean CPM = 3.315; ribosomal protein S6 kinase, 90kDa, polypeptide 6" ID="ID_498486837" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA3: 1.02-fold Up; FDR = 0.982; PValue = 0.829; mean CPM = 58.16; ribosomal protein S6 kinase, 90kDa, polypeptide 3" ID="ID_1278649232" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STK11: 1.01-fold Up; FDR = 1; PValue = 0.918; mean CPM = 47.98; serine/threonine kinase 11" ID="ID_1719964823" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF4E1B: No Change; FDR = 1; PValue = 0.997; mean CPM = 0.7963; eukaryotic translation initiation factor 4E family member 1B" ID="ID_840756098" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Cocaine addiction: Inhibited, FDR = 0.0779, FWER = 1, PValue = 0.02" ID="ID_1309414790" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CREB3L2: 2.11-fold Down; FDR = 5.05e-12; PValue = 9.78e-14; mean CPM = 64.33; cAMP responsive element binding protein 3-like 2" ID="ID_492700693" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3L1: 1.99-fold Down; FDR = 1.52e-09; PValue = 5.36e-11; mean CPM = 211.4; cAMP responsive element binding protein 3-like 1" ID="ID_572109766" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_796278415" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAI1: 1.47-fold Up; FDR = 5.94e-05; PValue = 6.9e-06; mean CPM = 97.19; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1" ID="ID_468545711" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACA: 1.36-fold Down; FDR = 0.000167; PValue = 2.22e-05; mean CPM = 37.75; protein kinase, cAMP-dependent, catalytic, alpha" ID="ID_1421631669" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB5: 2.1-fold Down; FDR = 0.000248; PValue = 3.48e-05; mean CPM = 4.269; cAMP responsive element binding protein 5" ID="ID_429830326" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF2: 1.34-fold Up; FDR = 0.000403; PValue = 6.01e-05; mean CPM = 39.83; activating transcription factor 2" ID="ID_13715414" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOSB: 2.11-fold Down; FDR = 0.000873; PValue = 0.000145; mean CPM = 81.52; FBJ murine osteosarcoma viral oncogene homolog B" ID="ID_286246501" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAS1: 1.31-fold Down; FDR = 0.00158; PValue = 0.000283; mean CPM = 564.9; Uncharacterized protein" ID="ID_1556026518" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK5R1: 2.32-fold Down; FDR = 0.00159; PValue = 0.000286; mean CPM = 2.216; cyclin-dependent kinase 5, regulatory subunit 1 (p35)" ID="ID_1355369183" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF4: 1.29-fold Up; FDR = 0.00296; PValue = 0.000579; mean CPM = 618.7; activating transcription factor 4 (tax-responsive enhancer element B67)" ID="ID_747178689" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRIN2C: 1.94-fold Down; FDR = 0.00298; PValue = 0.000582; mean CPM = 2.673; glutamate receptor, ionotropic, N-methyl D-aspartate 2C" ID="ID_1036471108" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKX: 1.31-fold Down; FDR = 0.00331; PValue = 0.000658; mean CPM = 24.94; protein kinase, X-linked" ID="ID_1356733163" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRIN2D: 2.02-fold Down; FDR = 0.00378; PValue = 0.00077; mean CPM = 3.190; glutamate receptor, ionotropic, N-methyl D-aspartate 2D" ID="ID_1532144537" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAI3: 1.26-fold Up; FDR = 0.00487; PValue = 0.00103; mean CPM = 113.8; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3" ID="ID_1860208669" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK5: 1.31-fold Up; FDR = 0.0067; PValue = 0.00148; mean CPM = 17.46; cyclin-dependent kinase 5" ID="ID_1166283858" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BDNF: 1.23-fold Down; FDR = 0.0158; PValue = 0.00399; mean CPM = 104.4; Brain-derived neurotrophic factor" ID="ID_1425523425" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GPSM1: 1.26-fold Down; FDR = 0.0255; PValue = 0.00696; mean CPM = 40.98; Uncharacterized protein" ID="ID_1926737771" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRIN2B: 3.63-fold Down; FDR = 0.0282; PValue = 0.00782; mean CPM = 1.577; glutamate receptor, ionotropic, N-methyl D-aspartate 2B" ID="ID_549073528" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB1: 1.21-fold Up; FDR = 0.0313; PValue = 0.00884; mean CPM = 36.07; cAMP responsive element binding protein 1" ID="ID_1712327751" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_820037193" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY5: 2.17-fold Down; FDR = 0.042; PValue = 0.0125; mean CPM = 1.219; adenylate cyclase 5" ID="ID_916866952" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3L4: 1.3-fold Down; FDR = 0.0961; PValue = 0.0334; mean CPM = 6.034; cAMP responsive element binding protein 3-like 4" ID="ID_1581588688" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3: 1.15-fold Up; FDR = 0.128; PValue = 0.0472; mean CPM = 167.9; cAMP responsive element binding protein 3" ID="ID_884468265" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAI2: 1.15-fold Down; FDR = 0.134; PValue = 0.0501; mean CPM = 356.3; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2" ID="ID_1177781538" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1785742295" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRIN3A: 1.46-fold Down; FDR = 0.241; PValue = 0.104; mean CPM = 1.717; glutamate receptor, ionotropic, N-methyl-D-aspartate 3A" ID="ID_1768670084" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRIN2A: 1.69-fold Down; FDR = 0.433; PValue = 0.214; mean CPM = 0.9509; glutamate receptor, ionotropic, N-methyl D-aspartate 2A" ID="ID_1561869" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRM2: 1.48-fold Down; FDR = 0.481; PValue = 0.246; mean CPM = 1.139; glutamate receptor, metabotropic 2" ID="ID_1436494486" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DRD1: 1.79-fold Up; FDR = 0.736; PValue = 0.438; mean CPM = 0.8307; dopamine receptor D1" ID="ID_1326580237" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREBL1: 1.05-fold Down; FDR = 0.794; PValue = 0.491; mean CPM = 64.18; activating transcription factor 6 beta" ID="ID_143798997" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACG: 1.51-fold Down; FDR = 0.795; PValue = 0.491; mean CPM = 0.8026; protein kinase, cAMP-dependent, catalytic, gamma" ID="ID_635373257" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRM3: 1.35-fold Up; FDR = 0.894; PValue = 0.618; mean CPM = 0.8214; glutamate receptor, metabotropic 3" ID="ID_643621829" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRIN1: 1.44-fold Up; FDR = 0.903; PValue = 0.646; mean CPM = 0.8658; glutamate receptor, ionotropic, N-methyl D-aspartate 1" ID="ID_1364613784" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RGS9: 1.15-fold Down; FDR = 0.903; PValue = 0.654; mean CPM = 1.286; regulator of G-protein signaling 9" ID="ID_330691640" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000021684: 1.44-fold Up; FDR = 0.903; PValue = 0.662; mean CPM = 0.8513; Uncharacterized protein" ID="ID_399792639" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3L3: 1.4-fold Down; FDR = 0.908; PValue = 0.679; mean CPM = 0.8407; cAMP responsive element binding protein 3-like 3" ID="ID_950257219" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACB: 1.03-fold Up; FDR = 0.911; PValue = 0.694; mean CPM = 30.10; protein kinase, cAMP-dependent, catalytic, beta" ID="ID_14486957" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRIN3B: 1.05-fold Up; FDR = 0.944; PValue = 0.764; mean CPM = 4.630; glutamate receptor, ionotropic, N-methyl-D-aspartate 3B" ID="ID_1270440858" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDYN: 1.22-fold Down; FDR = 0.946; PValue = 0.768; mean CPM = 0.8413; prodynorphin" ID="ID_207316791" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Rap1 signaling pathway: Inhibited, FDR = 0.0779, FWER = 1, PValue = 0.0212" ID="ID_1718849575" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CSF1: 7.34-fold Up; FDR = 4.6e-20; PValue = 1.69e-22; mean CPM = 149.8; colony stimulating factor 1 (macrophage)" ID="ID_1536603885" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MRAS: 2.04-fold Up; FDR = 4.47e-15; PValue = 4.43e-17; mean CPM = 41.38; muscle RAS oncogene homolog" ID="ID_1741500101" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFRA: 2.76-fold Up; FDR = 3.93e-14; PValue = 4.67e-16; mean CPM = 492.9; platelet-derived growth factor receptor, alpha polypeptide" ID="ID_865081751" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF1: 5.05-fold Down; FDR = 8.21e-14; PValue = 1.05e-15; mean CPM = 19.54; fibroblast growth factor 1 (acidic)" ID="ID_795481922" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VEGFC: 2-fold Up; FDR = 1.3e-13; PValue = 1.76e-15; mean CPM = 238.4; Macaca mulatta vascular endothelial growth factor C (VEGFC), mRNA." ID="ID_933499315" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MET: 2.57-fold Up; FDR = 3.56e-13; PValue = 5.22e-15; mean CPM = 242.4; Macaca mulatta met proto-oncogene (hepatocyte growth factor receptor) (MET), mRNA." ID="ID_1628628186" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASGRP3: 7.1-fold Up; FDR = 6.93e-13; PValue = 1.1e-14; mean CPM = 7.525; RAS guanyl releasing protein 3 (calcium and DAG-regulated)" ID="ID_4494657" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EPHA2: 2.06-fold Down; FDR = 4.54e-12; PValue = 8.63e-14; mean CPM = 77.86; EPH receptor A2" ID="ID_1355495789" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY6: 1.89-fold Down; FDR = 1.9e-10; PValue = 5.38e-12; mean CPM = 141.3; adenylate cyclase 6" ID="ID_1211693052" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB3: 5.02-fold Down; FDR = 1.72e-09; PValue = 6.17e-11; mean CPM = 43.21; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)" ID="ID_1677835262" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGFR: 1.84-fold Up; FDR = 6.71e-09; PValue = 2.77e-10; mean CPM = 68.58; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)" ID="ID_651225417" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF2: 2.42-fold Up; FDR = 9.98e-09; PValue = 4.31e-10; mean CPM = 134.8; fibroblast growth factor 2 (basic)" ID="ID_1011761148" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGFR2: 3.45-fold Down; FDR = 1.04e-08; PValue = 4.53e-10; mean CPM = 5.064; fibroblast growth factor receptor 2" ID="ID_1132471795" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INSR: 1.93-fold Down; FDR = 1.24e-08; PValue = 5.48e-10; mean CPM = 118.3; insulin receptor" ID="ID_54972178" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAGI1: 1.65-fold Down; FDR = 1.71e-07; PValue = 1e-08; mean CPM = 29.55; Uncharacterized protein" ID="ID_1759618898" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RALGDS: 2.6-fold Up; FDR = 2.12e-07; PValue = 1.28e-08; mean CPM = 47.88; ral guanine nucleotide dissociation stimulator" ID="ID_1228982351" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EFNA4: 3.75-fold Down; FDR = 2.37e-07; PValue = 1.45e-08; mean CPM = 2.749; ephrin-A4" ID="ID_771976217" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1B: 1.55-fold Up; FDR = 2.39e-07; PValue = 1.46e-08; mean CPM = 135.3; Ras-related protein Rap-1b; Ras-related protein Rap-1b isoform 1; Uncharacterized protein" ID="ID_451687834" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFA: 1.92-fold Down; FDR = 2.56e-07; PValue = 1.58e-08; mean CPM = 22.99; platelet-derived growth factor alpha polypeptide" ID="ID_1827281604" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1128162182" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCB1: 1.71-fold Up; FDR = 1.31e-06; PValue = 9.73e-08; mean CPM = 34.36; phospholipase C, beta 1 (phosphoinositide-specific)" ID="ID_745314830" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_279345087" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_1664121259" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THBS1: 2.74-fold Down; FDR = 1.68e-06; PValue = 1.28e-07; mean CPM = 25785; thrombospondin 1" ID="ID_960315220" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGFR3: 3.85-fold Down; FDR = 2.66e-06; PValue = 2.13e-07; mean CPM = 2.800; fibroblast growth factor receptor 3" ID="ID_1227754494" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC3: 1.68-fold Down; FDR = 2.72e-06; PValue = 2.19e-07; mean CPM = 13.98; ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)" ID="ID_895352943" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADORA2B: 2.02-fold Up; FDR = 4.38e-06; PValue = 3.72e-07; mean CPM = 24.72; adenosine A2b receptor" ID="ID_1026951471" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1: 5.76-fold Down; FDR = 6.73e-06; PValue = 6.04e-07; mean CPM = 1.536; insulin-like growth factor 1 (somatomedin C)" ID="ID_304302573" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K3: 1.45-fold Down; FDR = 7.01e-06; PValue = 6.34e-07; mean CPM = 180.1; mitogen-activated protein kinase kinase 3" ID="ID_895902891" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1R: 1.51-fold Down; FDR = 1.02e-05; PValue = 9.61e-07; mean CPM = 213.2; insulin-like growth factor 1 receptor" ID="ID_746737570" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1855742745" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAI1: 1.47-fold Up; FDR = 5.94e-05; PValue = 6.9e-06; mean CPM = 97.19; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1" ID="ID_968990226" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCE1: 3.26-fold Down; FDR = 6.36e-05; PValue = 7.45e-06; mean CPM = 11.49; phospholipase C, epsilon 1" ID="ID_259788397" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCAR1: 1.36-fold Up; FDR = 0.000193; PValue = 2.61e-05; mean CPM = 210.4; breast cancer anti-estrogen resistance 1" ID="ID_1906396267" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCB4: 1.75-fold Down; FDR = 0.00025; PValue = 3.52e-05; mean CPM = 6.730; phospholipase C, beta 4" ID="ID_500316861" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VEGFA: 1.47-fold Up; FDR = 0.000317; PValue = 4.59e-05; mean CPM = 463.7; vascular endothelial growth factor A" ID="ID_1065699582" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASGRP2: 2.4-fold Up; FDR = 0.000359; PValue = 5.28e-05; mean CPM = 5.834; Uncharacterized protein" ID="ID_946232586" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HGF: 1.85-fold Down; FDR = 0.000377; PValue = 5.58e-05; mean CPM = 137.4; hepatocyte growth factor (hepapoietin A; scatter factor)" ID="ID_724052618" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CNR1: 3.72-fold Up; FDR = 0.000381; PValue = 5.64e-05; mean CPM = 1.934; cannabinoid receptor 1 (brain)" ID="ID_253766224" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAPGEF4: 1.91-fold Down; FDR = 0.000537; PValue = 8.32e-05; mean CPM = 5.060; Rap guanine nucleotide exchange factor (GEF) 4" ID="ID_849862747" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAPGEF5: 3.8-fold Up; FDR = 0.000594; PValue = 9.3e-05; mean CPM = 2.507; Rap guanine nucleotide exchange factor (GEF) 5" ID="ID_99781038" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALM3: 1.41-fold Down; FDR = 0.000714; PValue = 0.000115; mean CPM = 94.24; calmodulin 3 (phosphorylase kinase, delta)" ID="ID_341200577" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ANGPT4: 4.02-fold Down; FDR = 0.000955; PValue = 0.00016; mean CPM = 1.231; angiopoietin 4" ID="ID_1329513944" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="P2RY1: 3.01-fold Up; FDR = 0.00101; PValue = 0.000171; mean CPM = 1.580; purinergic receptor P2Y, G-protein coupled, 1" ID="ID_1764538136" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAS1: 1.31-fold Down; FDR = 0.00158; PValue = 0.000283; mean CPM = 564.9; Uncharacterized protein" ID="ID_1199175463" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ID1: 1.64-fold Down; FDR = 0.00178; PValue = 0.000326; mean CPM = 22.90; inhibitor of DNA binding 1, dominant negative helix-loop-helix protein" ID="ID_833619700" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PFN2: 1.41-fold Up; FDR = 0.00199; PValue = 0.000369; mean CPM = 25.56; Profilin" ID="ID_1469535759" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NGF: 1.32-fold Up; FDR = 0.00212; PValue = 0.000396; mean CPM = 198.5; nerve growth factor (beta polypeptide)" ID="ID_515596823" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKD3: 1.29-fold Up; FDR = 0.00214; PValue = 0.0004; mean CPM = 43.43; protein kinase D3" ID="ID_653572094" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHOA: 1.28-fold Down; FDR = 0.00295; PValue = 0.000575; mean CPM = 277.8; ras homolog gene family, member A" ID="ID_556011062" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSF1R: 1.92-fold Down; FDR = 0.00308; PValue = 0.000604; mean CPM = 3.242; colony stimulating factor 1 receptor" ID="ID_1728589312" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RALA: 1.28-fold Up; FDR = 0.00322; PValue = 0.000638; mean CPM = 42.83; v-ral simian leukemia viral oncogene homolog A (ras related)" ID="ID_1966249280" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1B: 1.43-fold Up; FDR = 0.00346; PValue = 0.000693; mean CPM = 12.81; RAP1B, member of RAS oncogene family" ID="ID_1121718934" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EFNA2: 4.72-fold Down; FDR = 0.00348; PValue = 0.000699; mean CPM = 1.248; ephrin-A2" ID="ID_567499909" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG1: 1.31-fold Down; FDR = 0.00352; PValue = 0.000707; mean CPM = 53.66; phospholipase C, gamma 1" ID="ID_90412312" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAGI3: 1.57-fold Down; FDR = 0.00375; PValue = 0.000764; mean CPM = 7.924; membrane associated guanylate kinase, WW and PDZ domain containing 3" ID="ID_802831352" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAI3: 1.26-fold Up; FDR = 0.00487; PValue = 0.00103; mean CPM = 113.8; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3" ID="ID_1221820868" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VASP: 1.26-fold Down; FDR = 0.00581; PValue = 0.00126; mean CPM = 250.9; vasodilator-stimulated phosphoprotein" ID="ID_1503265849" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF12: 1.26-fold Up; FDR = 0.00782; PValue = 0.00177; mean CPM = 34.71; fibroblast growth factor 12" ID="ID_191484006" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYTSA: 1.68-fold Up; FDR = 0.0081; PValue = 0.00184; mean CPM = 18.59; cytospin A" ID="ID_1718733123" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY9: 1.32-fold Down; FDR = 0.00986; PValue = 0.00231; mean CPM = 84.04; adenylate cyclase 9" ID="ID_1412081346" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLN1: 1.26-fold Down; FDR = 0.0101; PValue = 0.00238; mean CPM = 1820; talin 1" ID="ID_206802901" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EFNA3: 2.71-fold Down; FDR = 0.0114; PValue = 0.00271; mean CPM = 1.699; ephrin-A3" ID="ID_1186947759" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EFNA1: 2.73-fold Down; FDR = 0.0114; PValue = 0.00272; mean CPM = 1.130; ephrin-A1" ID="ID_712645922" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFB: 1.97-fold Down; FDR = 0.0133; PValue = 0.00326; mean CPM = 2.424; platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)" ID="ID_1949485264" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCZ: 1.51-fold Up; FDR = 0.0152; PValue = 0.00381; mean CPM = 10.46; protein kinase C, zeta" ID="ID_1792542406" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FARP2: 1.24-fold Down; FDR = 0.0162; PValue = 0.00411; mean CPM = 30.03; FERM, RhoGEF and pleckstrin domain protein 2" ID="ID_790834968" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB2: 1.55-fold Down; FDR = 0.0187; PValue = 0.00485; mean CPM = 34.87; Integrin beta" ID="ID_1453014034" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA2B: 1.71-fold Down; FDR = 0.0187; PValue = 0.00486; mean CPM = 2.655; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)" ID="ID_117339473" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_530267300" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_940973028" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF21: 1.97-fold Up; FDR = 0.0263; PValue = 0.00722; mean CPM = 56.49; fibroblast growth factor 21" ID="ID_1627228679" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KRIT1: 1.23-fold Up; FDR = 0.0264; PValue = 0.00726; mean CPM = 32.04; KRIT1, ankyrin repeat containing" ID="ID_1710655120" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARAP3: 1.24-fold Down; FDR = 0.0271; PValue = 0.00747; mean CPM = 26.74; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3" ID="ID_790002479" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC2: 2.96-fold Up; FDR = 0.0309; PValue = 0.00872; mean CPM = 0.9737; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)" ID="ID_1156737869" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTNND1: 1.2-fold Down; FDR = 0.0315; PValue = 0.00892; mean CPM = 158.9; catenin (cadherin-associated protein), delta 1" ID="ID_1846585016" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KDR: 2.01-fold Up; FDR = 0.0328; PValue = 0.00936; mean CPM = 2.053; kinase insert domain receptor (a type III receptor tyrosine kinase)" ID="ID_759050562" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KRAS: 1.35-fold Down; FDR = 0.0401; PValue = 0.0119; mean CPM = 13.10; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog" ID="ID_1218192396" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY5: 2.17-fold Down; FDR = 0.042; PValue = 0.0125; mean CPM = 1.219; adenylate cyclase 5" ID="ID_577077328" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY7: 1.24-fold Down; FDR = 0.0434; PValue = 0.013; mean CPM = 157.2; adenylate cyclase 7" ID="ID_107590559" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCB2: 3.68-fold Down; FDR = 0.0481; PValue = 0.0147; mean CPM = 1.557; Uncharacterized protein" ID="ID_605331292" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTNNB1: 1.2-fold Up; FDR = 0.0498; PValue = 0.0153; mean CPM = 558.3; catenin (cadherin-associated protein), beta 1, 88kDa" ID="ID_905870221" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NRAS: 1.2-fold Down; FDR = 0.0546; PValue = 0.017; mean CPM = 32.39; neuroblastoma RAS viral (v-ras) oncogene homolog" ID="ID_4515346" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APBB1IP: 1.18-fold Up; FDR = 0.0644; PValue = 0.0208; mean CPM = 66.55; amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein" ID="ID_483964956" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_1463754383" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TIAM1: 1.23-fold Up; FDR = 0.0747; PValue = 0.0248; mean CPM = 38.38; T-cell lymphoma invasion and metastasis 1" ID="ID_620695209" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB1: 1.23-fold Up; FDR = 0.0759; PValue = 0.0253; mean CPM = 2700; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)" ID="ID_581706734" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF11: 1.44-fold Down; FDR = 0.0841; PValue = 0.0285; mean CPM = 3.869; fibroblast growth factor 11" ID="ID_1775560121" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1A: 1.17-fold Up; FDR = 0.0888; PValue = 0.0304; mean CPM = 37.16; RAP1A, member of RAS oncogene family" ID="ID_1951235169" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALM1: 1.18-fold Down; FDR = 0.104; PValue = 0.0368; mean CPM = 292.9; calmodulin 1 (phosphorylase kinase, delta)" ID="ID_1646347787" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PARD6B: 1.35-fold Up; FDR = 0.109; PValue = 0.0389; mean CPM = 6.109; par-6 partitioning defective 6 homolog beta (C. elegans)" ID="ID_1314883612" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAI2: 1.15-fold Down; FDR = 0.134; PValue = 0.0501; mean CPM = 356.3; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2" ID="ID_341417608" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGFR1: 1.15-fold Down; FDR = 0.139; PValue = 0.0525; mean CPM = 89.41; fibroblast growth factor receptor 1" ID="ID_566872553" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PARD6A: 1.64-fold Up; FDR = 0.151; PValue = 0.0579; mean CPM = 1.554; par-6 partitioning defective 6 homolog alpha (C. elegans)" ID="ID_173135941" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF23: 2.01-fold Down; FDR = 0.188; PValue = 0.0759; mean CPM = 0.9718; fibroblast growth factor 23" ID="ID_348798889" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TEK: 1.58-fold Down; FDR = 0.196; PValue = 0.0803; mean CPM = 2.573; TEK tyrosine kinase, endothelial" ID="ID_771645735" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KITLG: 1.31-fold Up; FDR = 0.209; PValue = 0.0867; mean CPM = 5.766; KIT ligand" ID="ID_1493036325" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BRAF: 1.14-fold Down; FDR = 0.228; PValue = 0.0964; mean CPM = 24.98; v-raf murine sarcoma viral oncogene homolog B1" ID="ID_539249931" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAT: 1.44-fold Down; FDR = 0.234; PValue = 0.0996; mean CPM = 1.871; linker for activation of T cells" ID="ID_177263080" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SIPA1L2: 1.47-fold Down; FDR = 0.243; PValue = 0.104; mean CPM = 6.689; signal-induced proliferation-associated 1 like 2" ID="ID_1737532926" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF10: 1.55-fold Down; FDR = 0.257; PValue = 0.112; mean CPM = 3.488; fibroblast growth factor 10" ID="ID_500163616" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_239399248" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SIPA1L1: 1.14-fold Up; FDR = 0.283; PValue = 0.125; mean CPM = 34.98; signal-induced proliferation-associated 1 like 1" ID="ID_1314692302" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NGFR: 1.72-fold Down; FDR = 0.285; PValue = 0.127; mean CPM = 1.174; nerve growth factor receptor" ID="ID_896847851" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY4: 1.24-fold Up; FDR = 0.328; PValue = 0.151; mean CPM = 8.390; adenylate cyclase 4" ID="ID_102884873" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_1197805746" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PFN1: 1.12-fold Down; FDR = 0.337; PValue = 0.156; mean CPM = 965.8; profilin 1" ID="ID_1923930409" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALM1: 1.11-fold Up; FDR = 0.343; PValue = 0.16; mean CPM = 412.7; Calmodulin; Uncharacterized protein" ID="ID_1179214201" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRKL: 1.11-fold Up; FDR = 0.371; PValue = 0.176; mean CPM = 34.10; v-crk sarcoma virus CT10 oncogene homolog (avian)-like" ID="ID_1620354909" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_904766291" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_1637472831" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RRAS: 1.1-fold Up; FDR = 0.415; PValue = 0.203; mean CPM = 223.0; related RAS viral (r-ras) oncogene homolog" ID="ID_1753671720" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_68510938" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK12: 1.19-fold Down; FDR = 0.422; PValue = 0.208; mean CPM = 6.569; mitogen-activated protein kinase 12" ID="ID_1636810855" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LPAR3: 2.49-fold Down; FDR = 0.429; PValue = 0.212; mean CPM = 0.8456; lysophosphatidic acid receptor 3" ID="ID_1373808195" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKD1: 1.14-fold Down; FDR = 0.433; PValue = 0.215; mean CPM = 41.81; protein kinase D1" ID="ID_1495700507" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_88235409" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FNIP1: 1.1-fold Down; FDR = 0.451; PValue = 0.226; mean CPM = 30.47; Uncharacterized protein" ID="ID_317787850" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="F2R: 1.1-fold Up; FDR = 0.458; PValue = 0.23; mean CPM = 35.05; coagulation factor II (thrombin) receptor" ID="ID_1240894738" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARAP1: 1.08-fold Down; FDR = 0.485; PValue = 0.248; mean CPM = 100.2; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1" ID="ID_390080872" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LCP2: 1.4-fold Up; FDR = 0.496; PValue = 0.256; mean CPM = 1.322; Uncharacterized protein" ID="ID_708882605" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PARD6G: 1.48-fold Down; FDR = 0.498; PValue = 0.257; mean CPM = 1.086; par-6 partitioning defective 6 homolog gamma (C. elegans)" ID="ID_911317303" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ANGPT1: 1.13-fold Up; FDR = 0.503; PValue = 0.26; mean CPM = 28.18; angiopoietin 1" ID="ID_1302580864" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PFN4: 1.47-fold Up; FDR = 0.506; PValue = 0.263; mean CPM = 1.137; profilin family, member 4" ID="ID_1954619167" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VEGFB: 1.1-fold Down; FDR = 0.512; PValue = 0.267; mean CPM = 16.03; vascular endothelial growth factor B" ID="ID_431067384" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCI: 1.08-fold Up; FDR = 0.518; PValue = 0.271; mean CPM = 47.99; protein kinase C, iota" ID="ID_1578207395" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARAP2: 1.61-fold Up; FDR = 0.525; PValue = 0.276; mean CPM = 0.9766; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2" ID="ID_1835847339" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_17666608" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK13: 1.22-fold Down; FDR = 0.536; PValue = 0.284; mean CPM = 3.100; mitogen-activated protein kinase 13" ID="ID_1064300150" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF18: 1.55-fold Down; FDR = 0.548; PValue = 0.293; mean CPM = 0.9359; fibroblast growth factor 18" ID="ID_1798433334" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PARD3: 1.07-fold Up; FDR = 0.581; PValue = 0.316; mean CPM = 129.4; par-3 partitioning defective 3 homolog (C. elegans)" ID="ID_95616360" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EFNA5: 1.52-fold Up; FDR = 0.605; PValue = 0.334; mean CPM = 0.9602; ephrin-A5" ID="ID_902642939" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDC42: 1.07-fold Down; FDR = 0.608; PValue = 0.335; mean CPM = 91.67; cell division cycle 42" ID="ID_1425266735" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCG: 1.47-fold Down; FDR = 0.609; PValue = 0.336; mean CPM = 0.9297; protein kinase C, gamma" ID="ID_1146198758" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF5: 1.1-fold Down; FDR = 0.646; PValue = 0.364; mean CPM = 54.02; fibroblast growth factor 5" ID="ID_571179743" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCB: 1.86-fold Up; FDR = 0.727; PValue = 0.43; mean CPM = 0.8705; protein kinase C, beta" ID="ID_85728627" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAM: 1.44-fold Down; FDR = 0.73; PValue = 0.432; mean CPM = 0.9052; integrin, alpha M (complement component 3 receptor 3 subunit)" ID="ID_1284175882" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASSF5: 1.2-fold Up; FDR = 0.734; PValue = 0.435; mean CPM = 2.403; Ras association (RalGDS/AF-6) domain family member 5" ID="ID_1818170034" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF9: 1.77-fold Up; FDR = 0.74; PValue = 0.441; mean CPM = 0.8485; fibroblast growth factor 9 (glia-activating factor)" ID="ID_151053107" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAPGEF1: 1.05-fold Down; FDR = 0.763; PValue = 0.462; mean CPM = 70.38; Rap guanine nucleotide exchange factor (GEF) 1" ID="ID_426185709" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF8: 1.75-fold Down; FDR = 0.783; PValue = 0.48; mean CPM = 0.8245; Uncharacterized protein" ID="ID_1055501013" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRK: 1.05-fold Up; FDR = 0.791; PValue = 0.488; mean CPM = 59.92; v-crk sarcoma virus CT10 oncogene homolog (avian)" ID="ID_1657366905" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF14: 1.13-fold Down; FDR = 0.809; PValue = 0.505; mean CPM = 6.007; fibroblast growth factor 14" ID="ID_1078324057" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALML5: 1.49-fold Up; FDR = 0.819; PValue = 0.518; mean CPM = 0.8129; calmodulin-like 5" ID="ID_1295475851" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SKAP1: 1.38-fold Up; FDR = 0.84; PValue = 0.546; mean CPM = 0.8034; src kinase associated phosphoprotein 1" ID="ID_403592802" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FLT1: 1.08-fold Down; FDR = 0.849; PValue = 0.558; mean CPM = 28.21; fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)" ID="ID_1661374324" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY2: 1.18-fold Down; FDR = 0.864; PValue = 0.58; mean CPM = 1.755; adenylate cyclase 2 (brain)" ID="ID_202463498" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1832166719" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF13: 1.24-fold Up; FDR = 0.882; PValue = 0.602; mean CPM = 1.024; Fibroblast growth factor 13 isoform 1; Uncharacterized protein" ID="ID_187219915" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALML6: 1.1-fold Up; FDR = 0.888; PValue = 0.61; mean CPM = 6.655; calmodulin-like 6" ID="ID_1449808726" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAQ: 1.05-fold Down; FDR = 0.889; PValue = 0.611; mean CPM = 9.623; Guanine nucleotide-binding protein G(Q) subunit alpha; Uncharacterized protein" ID="ID_1126092755" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY8: 1.28-fold Up; FDR = 0.891; PValue = 0.614; mean CPM = 0.8757; adenylate cyclase 8 (brain)" ID="ID_1632846462" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PFN3: 1.24-fold Down; FDR = 0.899; PValue = 0.631; mean CPM = 0.8001; profilin 3" ID="ID_525419477" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF3: 1.22-fold Down; FDR = 0.903; PValue = 0.641; mean CPM = 0.7938; fibroblast growth factor 3 (murine mammary tumor virus integration site (v-int-2) oncogene homolog)" ID="ID_1361670143" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="F2RL3: 1.16-fold Down; FDR = 0.903; PValue = 0.649; mean CPM = 0.7906; coagulation factor II (thrombin) receptor-like 3" ID="ID_986238282" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAGI2: 1.06-fold Down; FDR = 0.903; PValue = 0.655; mean CPM = 7.972; Uncharacterized protein" ID="ID_1148711794" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PFN3: 1.14-fold Down; FDR = 0.903; PValue = 0.658; mean CPM = 0.7895; Uncharacterized protein" ID="ID_1402829783" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF17: 1.34-fold Down; FDR = 0.903; PValue = 0.662; mean CPM = 0.8230; fibroblast growth factor 17" ID="ID_1291349595" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FPR1: 1.11-fold Up; FDR = 0.906; PValue = 0.671; mean CPM = 1.724; formyl peptide receptor 1" ID="ID_15638333" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY1: 1.13-fold Down; FDR = 0.908; PValue = 0.682; mean CPM = 1.243; adenylate cyclase 1 (brain)" ID="ID_1194440288" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FLT4: 1.19-fold Down; FDR = 0.909; PValue = 0.689; mean CPM = 0.8780; fms-related tyrosine kinase 4" ID="ID_1326592973" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LPAR4: 1.13-fold Up; FDR = 0.91; PValue = 0.693; mean CPM = 0.8442; lysophosphatidic acid receptor 4" ID="ID_1063450560" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALML3: 1.41-fold Down; FDR = 0.911; PValue = 0.698; mean CPM = 0.8159; calmodulin-like 3" ID="ID_1716221655" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAPGEF3: 1.04-fold Down; FDR = 0.914; PValue = 0.71; mean CPM = 11.75; Rap guanine nucleotide exchange factor (GEF) 3" ID="ID_1661580784" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF19: 1.33-fold Down; FDR = 0.921; PValue = 0.724; mean CPM = 0.8101; fibroblast growth factor 19" ID="ID_1060256748" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_1708798863" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF6: 1.15-fold Up; FDR = 0.948; PValue = 0.773; mean CPM = 0.8082; fibroblast growth factor 6" ID="ID_625763042" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_937390561" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016883: 1.11-fold Down; FDR = 0.97; PValue = 0.811; mean CPM = 0.8838; Uncharacterized protein" ID="ID_1714491287" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LPAR2: 1.06-fold Up; FDR = 0.989; PValue = 0.84; mean CPM = 1.309; lysophosphatidic acid receptor 2" ID="ID_796120557" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAO1: 1.1-fold Down; FDR = 1; PValue = 0.866; mean CPM = 0.8448; guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O" ID="ID_1471060512" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY3: 1.01-fold Up; FDR = 1; PValue = 0.871; mean CPM = 34.92; adenylate cyclase 3" ID="ID_599654763" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFRB: 1.01-fold Up; FDR = 1; PValue = 0.883; mean CPM = 391.1; platelet-derived growth factor receptor, beta polypeptide" ID="ID_464616289" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGF: 1.06-fold Down; FDR = 1; PValue = 0.885; mean CPM = 0.8917; epidermal growth factor" ID="ID_823999200" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDH1: 1.06-fold Down; FDR = 1; PValue = 0.899; mean CPM = 0.8823; cadherin 1, type 1, E-cadherin (epithelial)" ID="ID_304058607" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAL: 1.03-fold Up; FDR = 1; PValue = 0.95; mean CPM = 1.035; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)" ID="ID_899621463" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SIPA1: No Change; FDR = 1; PValue = 0.967; mean CPM = 43.27; Uncharacterized protein" ID="ID_1489214091" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAQ: No Change; FDR = 1; PValue = 0.975; mean CPM = 15.20; guanine nucleotide binding protein (G protein), q polypeptide" ID="ID_1794371395" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV2: No Change; FDR = 1; PValue = 0.976; mean CPM = 25.65; vav 2 guanine nucleotide exchange factor" ID="ID_286307408" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FIGF: 1.07-fold Up; FDR = 1; PValue = 0.995; mean CPM = 0.8037; c-fos induced growth factor (vascular endothelial growth factor D)" ID="ID_383047755" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF20: No Change; FDR = 1; PValue = 1; mean CPM = 0.7796; fibroblast growth factor 20" ID="ID_197849627" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Hepatitis C: Activated, FDR = 0.0779, FWER = 1, PValue = 0.0218" ID="ID_1167103698" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="IRF1: 18.6-fold Up; FDR = 1.53e-21; PValue = 4.24e-24; mean CPM = 240.7; interferon regulatory factor 1" ID="ID_283610003" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR3: 10.3-fold Up; FDR = 1.95e-21; PValue = 5.6e-24; mean CPM = 35.70; toll-like receptor 3" ID="ID_1249803812" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFIT1: 52.1-fold Up; FDR = 1.76e-20; PValue = 6.3e-23; mean CPM = 46.34; interferon-induced protein with tetratricopeptide repeats 1" ID="ID_1296884629" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF9: 3.85-fold Up; FDR = 2.6e-19; PValue = 1.12e-21; mean CPM = 106.4; interferon regulatory factor 9" ID="ID_410575205" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT2: 2.67-fold Up; FDR = 8.02e-19; PValue = 4.03e-21; mean CPM = 185.6; signal transducer and activator of transcription 2, 113kDa" ID="ID_1424362145" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1620724604" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DDX58: 6.4-fold Up; FDR = 5.12e-18; PValue = 3.06e-20; mean CPM = 86.14; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58" ID="ID_741429593" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2AK2: 3.01-fold Up; FDR = 6.08e-18; PValue = 3.74e-20; mean CPM = 47.85; eukaryotic translation initiation factor 2-alpha kinase 2" ID="ID_1145463098" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF7: 14.8-fold Up; FDR = 7.66e-18; PValue = 4.82e-20; mean CPM = 11.54; Macaca mulatta interferon regulatory factor 7 (IRF7), mRNA." ID="ID_1574534885" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAVS: 1.92-fold Down; FDR = 2.7e-09; PValue = 1.02e-10; mean CPM = 29.16; mitochondrial antiviral signaling protein" ID="ID_991064139" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_1350758041" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGFR: 1.84-fold Up; FDR = 6.71e-09; PValue = 2.77e-10; mean CPM = 68.58; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)" ID="ID_1289434219" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_1943740632" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_246745257" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFIT1L: 11.9-fold Up; FDR = 3.7e-08; PValue = 1.87e-09; mean CPM = 2.353; interferon-induced protein with tetratricopeptide repeats 1B" ID="ID_484070644" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1062900606" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1809052713" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_175655601" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR2: 1.74-fold Up; FDR = 1.85e-06; PValue = 1.44e-07; mean CPM = 26.05; interferon (alpha, beta and omega) receptor 2" ID="ID_1878432180" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_329938715" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2AK3: 1.59-fold Down; FDR = 2.47e-06; PValue = 1.96e-07; mean CPM = 33.81; eukaryotic translation initiation factor 2-alpha kinase 3" ID="ID_1118191749" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R1B: 1.39-fold Down; FDR = 4.37e-05; PValue = 4.86e-06; mean CPM = 233.1; protein phosphatase 2, regulatory subunit A, beta" ID="ID_820015233" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2S1: 1.42-fold Up; FDR = 5.59e-05; PValue = 6.42e-06; mean CPM = 79.87; eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa" ID="ID_993508513" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2CB: 1.35-fold Up; FDR = 0.000215; PValue = 2.96e-05; mean CPM = 59.68; protein phosphatase 2, catalytic subunit, beta isozyme" ID="ID_1072889951" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R2B: 7.66-fold Down; FDR = 0.000564; PValue = 8.78e-05; mean CPM = 4.510; protein phosphatase 2, regulatory subunit B, beta" ID="ID_1398467200" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAD: 1.36-fold Down; FDR = 0.000605; PValue = 9.52e-05; mean CPM = 48.46; BCL2-associated agonist of cell death" ID="ID_961194048" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS3: 1.69-fold Up; FDR = 0.000994; PValue = 0.000167; mean CPM = 37.76; suppressor of cytokine signaling 3" ID="ID_335230198" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIAS1: 1.3-fold Up; FDR = 0.00259; PValue = 0.000498; mean CPM = 29.99; protein inhibitor of activated STAT, 1" ID="ID_1285434667" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBK1: 1.3-fold Up; FDR = 0.00337; PValue = 0.000674; mean CPM = 30.46; TANK-binding kinase 1" ID="ID_291830931" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1747969753" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_849176510" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR1: 1.27-fold Up; FDR = 0.0101; PValue = 0.00237; mean CPM = 82.39; Uncharacterized protein" ID="ID_837862222" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYK2: 1.24-fold Down; FDR = 0.0142; PValue = 0.00354; mean CPM = 42.58; tyrosine kinase 2" ID="ID_1676003735" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1230660331" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_309559161" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRADD: 1.22-fold Up; FDR = 0.0319; PValue = 0.00907; mean CPM = 34.75; TNFRSF1A-associated via death domain" ID="ID_699333051" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDPK1: 1.24-fold Down; FDR = 0.0361; PValue = 0.0105; mean CPM = 17.53; 3-phosphoinositide dependent protein kinase-1" ID="ID_945792477" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1439335641" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KRAS: 1.35-fold Down; FDR = 0.0401; PValue = 0.0119; mean CPM = 13.10; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog" ID="ID_1295777899" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NRAS: 1.2-fold Down; FDR = 0.0546; PValue = 0.017; mean CPM = 32.39; neuroblastoma RAS viral (v-ras) oncogene homolog" ID="ID_89458348" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_1029949172" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_1698275135" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS2: 1.17-fold Up; FDR = 0.1; PValue = 0.0353; mean CPM = 31.79; son of sevenless homolog 2 (Drosophila)" ID="ID_1631180050" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_720463409" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_217229436" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_1523375006" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_969342301" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BRAF: 1.14-fold Down; FDR = 0.228; PValue = 0.0964; mean CPM = 24.98; v-raf murine sarcoma viral oncogene homolog B1" ID="ID_1402191489" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1A: 1.16-fold Down; FDR = 0.28; PValue = 0.124; mean CPM = 363.2; Cyclin-dependent kinase inhibitor 1; Uncharacterized protein" ID="ID_743939473" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_1015168894" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1A: 1.11-fold Up; FDR = 0.297; PValue = 0.134; mean CPM = 134.7; tumor necrosis factor receptor superfamily, member 1A" ID="ID_1118530251" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_1185768074" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP53: 1.11-fold Down; FDR = 0.364; PValue = 0.172; mean CPM = 33.25; tumor protein p53" ID="ID_844726821" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_151789847" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R2C: 1.48-fold Up; FDR = 0.391; PValue = 0.188; mean CPM = 1.318; protein phosphatase 2, regulatory subunit B, gamma" ID="ID_945091075" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TICAM1: 1.11-fold Down; FDR = 0.398; PValue = 0.192; mean CPM = 26.73; toll-like receptor adaptor molecule 1" ID="ID_666969519" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_1304289436" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_495496602" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK12: 1.19-fold Down; FDR = 0.422; PValue = 0.208; mean CPM = 6.569; mitogen-activated protein kinase 12" ID="ID_782262406" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1593699014" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2AK1: 1.09-fold Up; FDR = 0.499; PValue = 0.258; mean CPM = 34.88; Uncharacterized protein" ID="ID_1501296291" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_1894222038" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK13: 1.22-fold Down; FDR = 0.536; PValue = 0.284; mean CPM = 3.100; mitogen-activated protein kinase 13" ID="ID_650133395" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF3: 1.07-fold Up; FDR = 0.611; PValue = 0.338; mean CPM = 34.56; TNF receptor-associated factor 3" ID="ID_1010740884" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2AK4: 1.06-fold Up; FDR = 0.681; PValue = 0.391; mean CPM = 104.8; eukaryotic translation initiation factor 2 alpha kinase 4" ID="ID_1770975959" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNB1: 1.79-fold Up; FDR = 0.731; PValue = 0.433; mean CPM = 0.8526; interferon, beta 1, fibroblast" ID="ID_1581743791" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R2A: 1.06-fold Down; FDR = 0.733; PValue = 0.435; mean CPM = 44.53; protein phosphatase 2, regulatory subunit B, alpha" ID="ID_1780533529" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2CA: 1.05-fold Up; FDR = 0.8; PValue = 0.497; mean CPM = 62.78; protein phosphatase 2, catalytic subunit, alpha isozyme" ID="ID_354989002" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA6: 1.41-fold Down; FDR = 0.807; PValue = 0.504; mean CPM = 0.8019; interferon, alpha 6" ID="ID_1164312349" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF3E: 1.04-fold Up; FDR = 0.836; PValue = 0.542; mean CPM = 131.3; eukaryotic translation initiation factor 3, subunit E" ID="ID_1392544405" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1684653402" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_1608483116" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R2D: 1.04-fold Down; FDR = 0.899; PValue = 0.629; mean CPM = 19.98; protein phosphatase 2, regulatory subunit B, delta isoform" ID="ID_482869519" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA13: 1.13-fold Up; FDR = 0.908; PValue = 0.677; mean CPM = 0.7960; interferon, alpha 13" ID="ID_1011605452" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA8: 1.13-fold Down; FDR = 0.911; PValue = 0.702; mean CPM = 0.7910; interferon, alpha 8" ID="ID_1125794023" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKE: 1.03-fold Up; FDR = 0.929; PValue = 0.737; mean CPM = 21.61; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon" ID="ID_946460132" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_245381060" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA14: 1.22-fold Up; FDR = 0.965; PValue = 0.802; mean CPM = 0.8654; interferon, alpha 14" ID="ID_1439571316" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA4: 1.28-fold Down; FDR = 0.983; PValue = 0.829; mean CPM = 0.8584; interferon, alpha 4" ID="ID_1817241130" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGF: 1.06-fold Down; FDR = 1; PValue = 0.885; mean CPM = 0.8917; epidermal growth factor" ID="ID_562955562" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA1: No Change; FDR = 1; PValue = 0.998; mean CPM = 0.8014; interferon, alpha 1" ID="ID_376765236" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Prostate cancer: Inhibited, FDR = 0.0779, FWER = 1, PValue = 0.0231" ID="ID_105537104" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="PDGFRA: 2.76-fold Up; FDR = 3.93e-14; PValue = 4.67e-16; mean CPM = 492.9; platelet-derived growth factor receptor, alpha polypeptide" ID="ID_1896515388" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3L2: 2.11-fold Down; FDR = 5.05e-12; PValue = 9.78e-14; mean CPM = 64.33; cAMP responsive element binding protein 3-like 2" ID="ID_613518478" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3L1: 1.99-fold Down; FDR = 1.52e-09; PValue = 5.36e-11; mean CPM = 211.4; cAMP responsive element binding protein 3-like 1" ID="ID_1380301915" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_1017610880" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGFR: 1.84-fold Up; FDR = 6.71e-09; PValue = 2.77e-10; mean CPM = 68.58; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)" ID="ID_854386794" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGFR2: 3.45-fold Down; FDR = 1.04e-08; PValue = 4.53e-10; mean CPM = 5.064; fibroblast growth factor receptor 2" ID="ID_1254829773" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1B: 1.64-fold Up; FDR = 1.22e-08; PValue = 5.39e-10; mean CPM = 32.96; Cyclin-dependent kinase inhibitor 1B; Uncharacterized protein" ID="ID_1753469794" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1342776951" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RB1: 1.65-fold Up; FDR = 6.01e-08; PValue = 3.2e-09; mean CPM = 59.24; retinoblastoma 1" ID="ID_1914932045" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFA: 1.92-fold Down; FDR = 2.56e-07; PValue = 1.58e-08; mean CPM = 22.99; platelet-derived growth factor alpha polypeptide" ID="ID_1515217365" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_344071902" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1774962547" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_1034308888" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1: 5.76-fold Down; FDR = 6.73e-06; PValue = 6.04e-07; mean CPM = 1.536; insulin-like growth factor 1 (somatomedin C)" ID="ID_460238473" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1R: 1.51-fold Down; FDR = 1.02e-05; PValue = 9.61e-07; mean CPM = 213.2; insulin-like growth factor 1 receptor" ID="ID_1659177585" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_8725110" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90AA1: 1.41-fold Up; FDR = 4.17e-05; PValue = 4.62e-06; mean CPM = 609.6; heat shock protein 90kDa alpha (cytosolic), class A member 2" ID="ID_36598534" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB5: 2.1-fold Down; FDR = 0.000248; PValue = 3.48e-05; mean CPM = 4.269; cAMP responsive element binding protein 5" ID="ID_893937991" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AR: 2.06-fold Up; FDR = 0.000527; PValue = 8.13e-05; mean CPM = 4.804; Macaca mulatta androgen receptor (AR), mRNA." ID="ID_962665872" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAD: 1.36-fold Down; FDR = 0.000605; PValue = 9.52e-05; mean CPM = 48.46; BCL2-associated agonist of cell death" ID="ID_792807647" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOXO1: 1.49-fold Down; FDR = 0.00109; PValue = 0.000186; mean CPM = 11.95; forkhead box O1" ID="ID_431148019" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTOR: 1.3-fold Down; FDR = 0.00117; PValue = 0.000201; mean CPM = 107.5; mechanistic target of rapamycin (serine/threonine kinase)" ID="ID_1517299990" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF4: 1.29-fold Up; FDR = 0.00296; PValue = 0.000579; mean CPM = 618.7; activating transcription factor 4 (tax-responsive enhancer element B67)" ID="ID_1219785823" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1269703846" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90B1: 1.28-fold Down; FDR = 0.00538; PValue = 0.00115; mean CPM = 1017; heat shock protein 90kDa beta (Grp94), member 1" ID="ID_104012039" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MDM2: 1.32-fold Up; FDR = 0.00555; PValue = 0.00119; mean CPM = 148.6; Uncharacterized protein" ID="ID_1907115884" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NKX3-1: 2.56-fold Up; FDR = 0.00969; PValue = 0.00226; mean CPM = 1.846; NK3 homeobox 1" ID="ID_116106424" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFB: 1.97-fold Down; FDR = 0.0133; PValue = 0.00326; mean CPM = 2.424; platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)" ID="ID_889767473" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK2: 1.23-fold Down; FDR = 0.0194; PValue = 0.00507; mean CPM = 36.76; cyclin-dependent kinase 2" ID="ID_296488845" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_873878170" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_692629834" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB1: 1.21-fold Up; FDR = 0.0313; PValue = 0.00884; mean CPM = 36.07; cAMP responsive element binding protein 1" ID="ID_1497069013" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDPK1: 1.24-fold Down; FDR = 0.0361; PValue = 0.0105; mean CPM = 17.53; 3-phosphoinositide dependent protein kinase-1" ID="ID_1745905121" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TCF7: 1.72-fold Down; FDR = 0.0376; PValue = 0.011; mean CPM = 4.279; transcription factor 7 (T-cell specific, HMG-box)" ID="ID_1222573269" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_145411294" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KRAS: 1.35-fold Down; FDR = 0.0401; PValue = 0.0119; mean CPM = 13.10; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog" ID="ID_1800479468" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="E2F1: 1.44-fold Down; FDR = 0.0425; PValue = 0.0127; mean CPM = 8.857; E2F transcription factor 1" ID="ID_1949859208" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTNNB1: 1.2-fold Up; FDR = 0.0498; PValue = 0.0153; mean CPM = 558.3; catenin (cadherin-associated protein), beta 1, 88kDa" ID="ID_247312866" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NRAS: 1.2-fold Down; FDR = 0.0546; PValue = 0.017; mean CPM = 32.39; neuroblastoma RAS viral (v-ras) oncogene homolog" ID="ID_188731317" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_97675919" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TCF7L1: 1.2-fold Down; FDR = 0.0783; PValue = 0.0262; mean CPM = 25.11; transcription factor 7-like 1 (T-cell specific, HMG-box)" ID="ID_352410714" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3L4: 1.3-fold Down; FDR = 0.0961; PValue = 0.0334; mean CPM = 6.034; cAMP responsive element binding protein 3-like 4" ID="ID_605789533" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS2: 1.17-fold Up; FDR = 0.1; PValue = 0.0353; mean CPM = 31.79; son of sevenless homolog 2 (Drosophila)" ID="ID_1052008718" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_376049648" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND1: 1.17-fold Up; FDR = 0.121; PValue = 0.0443; mean CPM = 867.3; cyclin D1" ID="ID_896321242" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3: 1.15-fold Up; FDR = 0.128; PValue = 0.0472; mean CPM = 167.9; cAMP responsive element binding protein 3" ID="ID_1677495205" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_86374083" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGFR1: 1.15-fold Down; FDR = 0.139; PValue = 0.0525; mean CPM = 89.41; fibroblast growth factor receptor 1" ID="ID_301097047" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTEN: 1.14-fold Up; FDR = 0.166; PValue = 0.065; mean CPM = 89.60; phosphatase and tensin homolog" ID="ID_1956605350" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_186953576" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BRAF: 1.14-fold Down; FDR = 0.228; PValue = 0.0964; mean CPM = 24.98; v-raf murine sarcoma viral oncogene homolog B1" ID="ID_485092627" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ERBB2: 1.14-fold Down; FDR = 0.23; PValue = 0.0977; mean CPM = 119.0; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)" ID="ID_1181392055" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNE1: 1.2-fold Up; FDR = 0.278; PValue = 0.123; mean CPM = 6.609; cyclin E1" ID="ID_1849114633" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1A: 1.16-fold Down; FDR = 0.28; PValue = 0.124; mean CPM = 363.2; Cyclin-dependent kinase inhibitor 1; Uncharacterized protein" ID="ID_1302394310" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_1240406139" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EP300: 1.11-fold Up; FDR = 0.312; PValue = 0.142; mean CPM = 162.8; E1A binding protein p300" ID="ID_451617516" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INSRR: 1.92-fold Down; FDR = 0.323; PValue = 0.149; mean CPM = 0.9773; insulin receptor-related receptor" ID="ID_532878766" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_1497903908" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP53: 1.11-fold Down; FDR = 0.364; PValue = 0.172; mean CPM = 33.25; tumor protein p53" ID="ID_1798525885" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1981853844" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2: 1.48-fold Up; FDR = 0.384; PValue = 0.184; mean CPM = 1.344; Uncharacterized protein" ID="ID_1984299376" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_145101456" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_1570548738" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90AB1: 1.07-fold Down; FDR = 0.652; PValue = 0.369; mean CPM = 905.8; heat shock protein 90kDa alpha (cytosolic), class B member 1" ID="ID_499300743" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LEF1: 1.2-fold Up; FDR = 0.691; PValue = 0.4; mean CPM = 2.488; lymphoid enhancer-binding factor 1" ID="ID_1237565260" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFA: 1.89-fold Up; FDR = 0.725; PValue = 0.428; mean CPM = 0.8701; transforming growth factor, alpha" ID="ID_1604669900" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90AA1: 1.8-fold Up; FDR = 0.749; PValue = 0.449; mean CPM = 0.8328; heat shock protein 90kDa alpha (cytosolic), class A member 1" ID="ID_127790363" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="E2F3: 1.08-fold Up; FDR = 0.751; PValue = 0.452; mean CPM = 11.79; E2F transcription factor 3" ID="ID_176057332" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_301518712" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1994224633" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3L3: 1.4-fold Down; FDR = 0.908; PValue = 0.679; mean CPM = 0.8407; cAMP responsive element binding protein 3-like 3" ID="ID_1035464845" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_742438113" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNE2: 1.05-fold Up; FDR = 0.962; PValue = 0.796; mean CPM = 6.415; cyclin E2" ID="ID_1600728257" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREBBP: 1.01-fold Down; FDR = 0.993; PValue = 0.847; mean CPM = 137.7; CREB binding protein" ID="ID_1863305951" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFRB: 1.01-fold Up; FDR = 1; PValue = 0.883; mean CPM = 391.1; platelet-derived growth factor receptor, beta polypeptide" ID="ID_581543649" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGF: 1.06-fold Down; FDR = 1; PValue = 0.885; mean CPM = 0.8917; epidermal growth factor" ID="ID_367866954" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="E2F2: 1.03-fold Up; FDR = 1; PValue = 0.906; mean CPM = 1.976; E2F transcription factor 2" ID="ID_40652943" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP9: 1.01-fold Up; FDR = 1; PValue = 0.908; mean CPM = 19.86; caspase 9, apoptosis-related cysteine peptidase" ID="ID_74890989" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KLK3: No Change; FDR = 1; PValue = 1; mean CPM = 0.7851; kallikrein-related peptidase 3" ID="ID_840205681" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Pathogenic Escherichia coli infection: Inhibited, FDR = 0.0779, FWER = 1, PValue = 0.0235" ID="ID_740937731" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TUBB6: 1.71-fold Down; FDR = 2.32e-09; PValue = 8.53e-11; mean CPM = 226.9; tubulin, beta 6" ID="ID_603461620" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR4: 3.45-fold Up; FDR = 3.1e-09; PValue = 1.19e-10; mean CPM = 7.456; Macaca mulatta toll-like receptor 4 (TLR4), mRNA." ID="ID_1877469428" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TUBA1C: 1.9-fold Down; FDR = 9.51e-09; PValue = 4.08e-10; mean CPM = 246.6; tubulin, alpha 1c" ID="ID_1992746578" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TUBA4A: 2.93-fold Down; FDR = 1.64e-07; PValue = 9.65e-09; mean CPM = 6.726; tubulin, alpha 4a" ID="ID_1147579715" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD14: 2.75-fold Down; FDR = 6.54e-07; PValue = 4.46e-08; mean CPM = 5.195; CD14 molecule" ID="ID_1573482511" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TUBB2C: 1.51-fold Down; FDR = 2.01e-06; PValue = 1.56e-07; mean CPM = 365.4; tubulin, beta 2C" ID="ID_1060866974" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TUBB: 1.63-fold Down; FDR = 3.21e-06; PValue = 2.63e-07; mean CPM = 139.4; Tubulin beta chain (Tubulin beta-5 chain)" ID="ID_115938131" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TUBA1B: 1.59-fold Down; FDR = 4.67e-06; PValue = 3.99e-07; mean CPM = 1284; tubulin, alpha 1b" ID="ID_508335159" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TUBA1A: 1.66-fold Down; FDR = 7.24e-06; PValue = 6.58e-07; mean CPM = 305.6; tubulin, alpha 1a" ID="ID_996966962" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TUBB2A: 1.3-fold Down; FDR = 0.00209; PValue = 0.00039; mean CPM = 43.58; tubulin, beta 2A" ID="ID_238433240" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHOA: 1.28-fold Down; FDR = 0.00295; PValue = 0.000575; mean CPM = 277.8; ras homolog gene family, member A" ID="ID_1052702399" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WASL: 1.26-fold Up; FDR = 0.00781; PValue = 0.00177; mean CPM = 33.90; Wiskott-Aldrich syndrome-like" ID="ID_222383360" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TUBB1: 2.42-fold Up; FDR = 0.0219; PValue = 0.00583; mean CPM = 1.363; tubulin, beta 1" ID="ID_75699258" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARPC4: 1.19-fold Down; FDR = 0.0498; PValue = 0.0153; mean CPM = 127.9; actin related protein 2/3 complex, subunit 4, 20kDa" ID="ID_1482892390" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ROCK2: 1.14-fold Up; FDR = 0.166; PValue = 0.065; mean CPM = 247.7; Rho-associated, coiled-coil containing protein kinase 2" ID="ID_509703415" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARHGEF2: 1.11-fold Up; FDR = 0.313; PValue = 0.143; mean CPM = 383.1; Rho/Rac guanine nucleotide exchange factor (GEF) 2" ID="ID_848667052" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARPC1A: 1.11-fold Down; FDR = 0.316; PValue = 0.144; mean CPM = 108.5; actin related protein 2/3 complex, subunit 1A, 41kDa" ID="ID_1800590013" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TUBA3D: 1.64-fold Down; FDR = 0.374; PValue = 0.178; mean CPM = 1.008; tubulin, alpha 3d" ID="ID_457517383" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARPC2: 1.1-fold Up; FDR = 0.401; PValue = 0.195; mean CPM = 335.6; actin related protein 2/3 complex, subunit 2, 34kDa" ID="ID_697509392" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TUBA1C: 1.61-fold Up; FDR = 0.406; PValue = 0.197; mean CPM = 1.068; tubulin, alpha 1c" ID="ID_1119792234" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000027858: 1.25-fold Down; FDR = 0.686; PValue = 0.396; mean CPM = 1.526; Uncharacterized protein" ID="ID_1462272170" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TUBA3C: 1.66-fold Down; FDR = 0.747; PValue = 0.447; mean CPM = 0.8119; tubulin, alpha 3c" ID="ID_441773015" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WAS: 1.37-fold Down; FDR = 0.771; PValue = 0.469; mean CPM = 0.9085; Wiskott-Aldrich syndrome" ID="ID_850948700" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RP11-631M21.2: 1.16-fold Down; FDR = 0.904; PValue = 0.663; mean CPM = 0.7937; Tubulin beta-8 chain" ID="ID_184033041" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TUBB4: 1.15-fold Up; FDR = 0.907; PValue = 0.674; mean CPM = 0.7950; tubulin, beta 4" ID="ID_1967446571" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARPC5L: 1.03-fold Up; FDR = 0.914; PValue = 0.713; mean CPM = 17.63; actin related protein 2/3 complex, subunit 5-like" ID="ID_1616348912" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033972: 1.19-fold Down; FDR = 0.982; PValue = 0.828; mean CPM = 0.8457" ID="ID_1110889896" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000028735: No Change; FDR = 1; PValue = 1; mean CPM = 0.7796; Uncharacterized protein" ID="ID_1496726259" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Malaria: Activated, FDR = 0.0779, FWER = 1, PValue = 0.0235" ID="ID_1263694879" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TLR2: 8.94-fold Up; FDR = 6.97e-23; PValue = 1.25e-25; mean CPM = 18.41; toll-like receptor 2" ID="ID_1157540185" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICAM1: 24.6-fold Up; FDR = 2.39e-17; PValue = 1.64e-19; mean CPM = 232.4; intercellular adhesion molecule 1" ID="ID_1593368387" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MET: 2.57-fold Up; FDR = 3.56e-13; PValue = 5.22e-15; mean CPM = 242.4; Macaca mulatta met proto-oncogene (hepatocyte growth factor receptor) (MET), mRNA." ID="ID_528034732" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR4: 3.45-fold Up; FDR = 3.1e-09; PValue = 1.19e-10; mean CPM = 7.456; Macaca mulatta toll-like receptor 4 (TLR4), mRNA." ID="ID_1558176822" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HGF: 1.85-fold Down; FDR = 0.000377; PValue = 5.58e-05; mean CPM = 137.4; hepatocyte growth factor (hepapoietin A; scatter factor)" ID="ID_1369580526" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40: 2.76-fold Up; FDR = 0.00039; PValue = 5.79e-05; mean CPM = 9.139; CD40 molecule, TNF receptor superfamily member 5" ID="ID_568423901" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB2: 1.55-fold Down; FDR = 0.0187; PValue = 0.00485; mean CPM = 34.87; Integrin beta" ID="ID_1530264163" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR9: 1.01-fold Down; FDR = 1; PValue = 0.859; mean CPM = 21.45; Macaca mulatta toll-like receptor 9 (TLR9), mRNA." ID="ID_51211418" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAL: 1.03-fold Up; FDR = 1; PValue = 0.95; mean CPM = 1.035; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)" ID="ID_1116467308" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40LG: 1.01-fold Down; FDR = 1; PValue = 0.982; mean CPM = 0.8653; CD40 ligand" ID="ID_696859295" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Endocrine and other factor-regulated calcium reabsorption: Inhibited, FDR = 0.0779, FWER = 1, PValue = 0.0235" ID="ID_1919185096" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="ATP1A2: 12.5-fold Down; FDR = 4.89e-13; PValue = 7.44e-15; mean CPM = 10.52; ATPase, Na+/K+ transporting, alpha 2 polypeptide" ID="ID_1682021083" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP1B1: 2.02-fold Down; FDR = 1.14e-10; PValue = 3.02e-12; mean CPM = 121.2; Sodium/potassium-transporting ATPase subunit beta-1; Uncharacterized protein" ID="ID_246192104" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY6: 1.89-fold Down; FDR = 1.9e-10; PValue = 5.38e-12; mean CPM = 141.3; adenylate cyclase 6" ID="ID_1150821762" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ESR1: 5.04-fold Up; FDR = 6.62e-08; PValue = 3.55e-09; mean CPM = 2.845; estrogen receptor 1" ID="ID_1740281752" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCB1: 1.71-fold Up; FDR = 1.31e-06; PValue = 9.73e-08; mean CPM = 34.36; phospholipase C, beta 1 (phosphoinositide-specific)" ID="ID_844463701" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACA: 1.36-fold Down; FDR = 0.000167; PValue = 2.22e-05; mean CPM = 37.75; protein kinase, cAMP-dependent, catalytic, alpha" ID="ID_1530138077" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCB4: 1.75-fold Down; FDR = 0.00025; PValue = 3.52e-05; mean CPM = 6.730; phospholipase C, beta 4" ID="ID_329363454" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAS1: 1.31-fold Down; FDR = 0.00158; PValue = 0.000283; mean CPM = 564.9; Uncharacterized protein" ID="ID_1921861216" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKX: 1.31-fold Down; FDR = 0.00331; PValue = 0.000658; mean CPM = 24.94; protein kinase, X-linked" ID="ID_896845525" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KLK1: 5.08-fold Down; FDR = 0.00702; PValue = 0.00156; mean CPM = 1.105; kallikrein 1" ID="ID_179566453" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY9: 1.32-fold Down; FDR = 0.00986; PValue = 0.00231; mean CPM = 84.04; adenylate cyclase 9" ID="ID_70799281" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP1A1: 1.22-fold Down; FDR = 0.0272; PValue = 0.00752; mean CPM = 361.3; ATPase, Na+/K+ transporting, alpha 1 polypeptide" ID="ID_1410212930" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCB2: 3.68-fold Down; FDR = 0.0481; PValue = 0.0147; mean CPM = 1.557; Uncharacterized protein" ID="ID_338633949" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP1B3: 1.19-fold Down; FDR = 0.0573; PValue = 0.0181; mean CPM = 46.02; ATPase, Na+/K+ transporting, beta 3 polypeptide" ID="ID_1951025089" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP1B3: 1.3-fold Down; FDR = 0.0737; PValue = 0.0244; mean CPM = 6.672; Uncharacterized protein" ID="ID_1909791878" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTH1R: 2-fold Down; FDR = 0.0838; PValue = 0.0284; mean CPM = 1.299; parathyroid hormone 1 receptor" ID="ID_273747843" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAB11A: 1.15-fold Up; FDR = 0.141; PValue = 0.0532; mean CPM = 75.55; Ras-related protein Rab-11A isoform 1; Uncharacterized protein" ID="ID_1209524565" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP1A4: 1.92-fold Down; FDR = 0.235; PValue = 0.1; mean CPM = 1.006; ATPase, Na+/K+ transporting, alpha 4 polypeptide" ID="ID_1004790546" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCG: 1.47-fold Down; FDR = 0.609; PValue = 0.336; mean CPM = 0.9297; protein kinase C, gamma" ID="ID_1849783736" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCB: 1.86-fold Up; FDR = 0.727; PValue = 0.43; mean CPM = 0.8705; protein kinase C, beta" ID="ID_76505841" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP1B4: 1.87-fold Up; FDR = 0.756; PValue = 0.455; mean CPM = 0.8457; ATPase, Na+/K+ transporting, beta 4 polypeptide" ID="ID_441147732" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACG: 1.51-fold Down; FDR = 0.795; PValue = 0.491; mean CPM = 0.8026; protein kinase, cAMP-dependent, catalytic, gamma" ID="ID_1784906190" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC8A1: 1.09-fold Up; FDR = 0.798; PValue = 0.495; mean CPM = 10.34; solute carrier family 8 (sodium/calcium exchanger), member 1" ID="ID_1020925804" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KL: 1.4-fold Up; FDR = 0.849; PValue = 0.559; mean CPM = 0.8285; klotho" ID="ID_1056401979" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAQ: 1.05-fold Down; FDR = 0.889; PValue = 0.611; mean CPM = 9.623; Guanine nucleotide-binding protein G(Q) subunit alpha; Uncharacterized protein" ID="ID_259644518" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FXYD2: 1.25-fold Up; FDR = 0.898; PValue = 0.624; mean CPM = 0.7915; FXYD domain containing ion transport regulator 2" ID="ID_1925127396" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KLK2: 1.52-fold Up; FDR = 0.899; PValue = 0.634; mean CPM = 0.8292; kallikrein-related peptidase 2" ID="ID_845123869" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000021684: 1.44-fold Up; FDR = 0.903; PValue = 0.662; mean CPM = 0.8513; Uncharacterized protein" ID="ID_1536111471" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACB: 1.03-fold Up; FDR = 0.911; PValue = 0.694; mean CPM = 30.10; protein kinase, cAMP-dependent, catalytic, beta" ID="ID_824870040" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BDKRB2: 1.04-fold Down; FDR = 0.964; PValue = 0.801; mean CPM = 6.559; bradykinin receptor B2" ID="ID_1920152157" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALB1: 1.07-fold Down; FDR = 0.994; PValue = 0.849; mean CPM = 1.025; calbindin 1, 28kDa" ID="ID_1678325" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP1B2: 1.12-fold Down; FDR = 1; PValue = 0.958; mean CPM = 0.8232; ATPase, Na+/K+ transporting, beta 2 polypeptide" ID="ID_649425109" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRPV5: 1.09-fold Down; FDR = 1; PValue = 0.969; mean CPM = 0.8655; transient receptor potential cation channel, subfamily V, member 5" ID="ID_570316886" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAQ: No Change; FDR = 1; PValue = 0.975; mean CPM = 15.20; guanine nucleotide binding protein (G protein), q polypeptide" ID="ID_989914394" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Intestinal immune network for IgA production: Activated, FDR = 0.0779, FWER = 1, PValue = 0.0236" ID="ID_1606804859" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TNFSF13B: 123-fold Up; FDR = 9.32e-25; PValue = 7.44e-28; mean CPM = 49.02; tumor necrosis factor (ligand) superfamily, member 13b" ID="ID_1912838490" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL15: 17.3-fold Up; FDR = 2.78e-17; PValue = 1.92e-19; mean CPM = 5.103; Macaca mulatta interleukin 15 (IL15), mRNA." ID="ID_227479636" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL15RA: 19.4-fold Up; FDR = 4.04e-17; PValue = 2.89e-19; mean CPM = 5.291; interleukin 15 receptor, alpha" ID="ID_372573943" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40: 2.76-fold Up; FDR = 0.00039; PValue = 5.79e-05; mean CPM = 9.139; CD40 molecule, TNF receptor superfamily member 5" ID="ID_1149456558" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCR4: 4.65-fold Down; FDR = 0.00226; PValue = 0.000426; mean CPM = 2.073; chemokine (C-X-C motif) receptor 4" ID="ID_1140584883" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR9: 3.89-fold Down; FDR = 0.00547; PValue = 0.00117; mean CPM = 0.9346; chemokine (C-C motif) receptor 9" ID="ID_1833088995" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K14: 1.47-fold Down; FDR = 0.00704; PValue = 0.00157; mean CPM = 9.470; mitogen-activated protein kinase kinase kinase 14" ID="ID_1381185240" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL28: 2.67-fold Up; FDR = 0.0616; PValue = 0.0197; mean CPM = 1.020; chemokine (C-C motif) ligand 28" ID="ID_1106340246" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL12: 1.27-fold Down; FDR = 0.488; PValue = 0.251; mean CPM = 4.383; chemokine (C-X-C motif) ligand 12" ID="ID_414726310" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LTBR: 1.06-fold Down; FDR = 0.683; PValue = 0.394; mean CPM = 91.13; lymphotoxin beta receptor (TNFR superfamily, member 3)" ID="ID_484164184" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA4: 1.16-fold Down; FDR = 0.722; PValue = 0.425; mean CPM = 5.425; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)" ID="ID_1838495869" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICOSLG: 1.07-fold Down; FDR = 0.909; PValue = 0.684; mean CPM = 6.739; inducible T-cell co-stimulator ligand" ID="ID_958562188" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MADCAM1: 1.11-fold Up; FDR = 0.909; PValue = 0.688; mean CPM = 0.7934; mucosal vascular addressin cell adhesion molecule 1" ID="ID_931395926" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICOS: 1.19-fold Up; FDR = 0.931; PValue = 0.741; mean CPM = 0.8158; Uncharacterized protein" ID="ID_1135346833" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF17: 1.08-fold Down; FDR = 0.954; PValue = 0.783; mean CPM = 1.418; tumor necrosis factor receptor superfamily, member 17" ID="ID_1682518086" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF13B: 1.06-fold Up; FDR = 0.954; PValue = 0.784; mean CPM = 0.8104; tumor necrosis factor receptor superfamily, member 13B" ID="ID_402875096" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD80: 1.08-fold Up; FDR = 0.971; PValue = 0.812; mean CPM = 1.157; CD80 molecule" ID="ID_1012441553" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL25: 1.05-fold Down; FDR = 1; PValue = 0.872; mean CPM = 1.770; chemokine (C-C motif) ligand 25" ID="ID_1162444070" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR10: 1.01-fold Down; FDR = 1; PValue = 0.929; mean CPM = 4.275; chemokine (C-C motif) receptor 10" ID="ID_207132949" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000006973: 1.09-fold Down; FDR = 1; PValue = 0.938; mean CPM = 0.8165; Uncharacterized protein" ID="ID_991109611" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB7: 1.01-fold Down; FDR = 1; PValue = 0.968; mean CPM = 2.025; integrin, beta 7" ID="ID_76755142" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40LG: 1.01-fold Down; FDR = 1; PValue = 0.982; mean CPM = 0.8653; CD40 ligand" ID="ID_1091515694" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD86: 1.01-fold Down; FDR = 1; PValue = 0.99; mean CPM = 0.8012; CD86 molecule" ID="ID_257259088" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000007111: 1.12-fold Down; FDR = 1; PValue = 0.993; mean CPM = 0.8245; Uncharacterized protein" ID="ID_365371445" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Phosphatidylinositol signaling system: Activated, FDR = 0.081, FWER = 1, PValue = 0.0255" ID="ID_1796328532" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="PI4K2B: 2.08-fold Up; FDR = 1.37e-13; PValue = 1.86e-15; mean CPM = 26.83; phosphatidylinositol 4-kinase type 2 beta" ID="ID_1708073899" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SYNJ2: 2.41-fold Down; FDR = 8.44e-12; PValue = 1.73e-13; mean CPM = 85.93; synaptojanin 2" ID="ID_1900110853" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCD3: 1.96-fold Down; FDR = 1.98e-08; PValue = 9.29e-10; mean CPM = 26.23; phospholipase C, delta 3" ID="ID_1227063460" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DGKG: 3.46-fold Up; FDR = 8.02e-08; PValue = 4.38e-09; mean CPM = 4.890; diacylglycerol kinase, gamma 90kDa" ID="ID_1262138365" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1614716307" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DGKA: 1.58-fold Down; FDR = 5.17e-07; PValue = 3.42e-08; mean CPM = 51.78; diacylglycerol kinase, alpha 80kDa" ID="ID_1989822249" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCB1: 1.71-fold Up; FDR = 1.31e-06; PValue = 9.73e-08; mean CPM = 34.36; phospholipase C, beta 1 (phosphoinositide-specific)" ID="ID_911572411" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1540562873" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIP5K2A: 1.46-fold Up; FDR = 5.17e-06; PValue = 4.47e-07; mean CPM = 34.65; phosphatidylinositol-5-phosphate 4-kinase, type II, alpha" ID="ID_1433762940" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCE1: 3.26-fold Down; FDR = 6.36e-05; PValue = 7.45e-06; mean CPM = 11.49; phospholipase C, epsilon 1" ID="ID_435322873" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INPP5A: 1.53-fold Down; FDR = 0.000125; PValue = 1.59e-05; mean CPM = 35.75; inositol polyphosphate-5-phosphatase, 40kDa" ID="ID_1008527690" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTM1: 1.49-fold Up; FDR = 0.000152; PValue = 2e-05; mean CPM = 17.20; Uncharacterized protein" ID="ID_690208295" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDS2: 1.36-fold Up; FDR = 0.000235; PValue = 3.28e-05; mean CPM = 35.01; CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2" ID="ID_1609614819" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCB4: 1.75-fold Down; FDR = 0.00025; PValue = 3.52e-05; mean CPM = 6.730; phospholipase C, beta 4" ID="ID_211198082" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DGKD: 1.44-fold Down; FDR = 0.000685; PValue = 0.000109; mean CPM = 24.48; diacylglycerol kinase, delta 130kDa" ID="ID_1529589200" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALM3: 1.41-fold Down; FDR = 0.000714; PValue = 0.000115; mean CPM = 94.24; calmodulin 3 (phosphorylase kinase, delta)" ID="ID_718382046" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIP4K2C: 1.39-fold Up; FDR = 0.00119; PValue = 0.000205; mean CPM = 16.06; phosphatidylinositol-5-phosphate 4-kinase, type II, gamma" ID="ID_211863867" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITPKB: 1.56-fold Down; FDR = 0.00312; PValue = 0.000615; mean CPM = 11.78; inositol-trisphosphate 3-kinase B" ID="ID_586533737" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG1: 1.31-fold Down; FDR = 0.00352; PValue = 0.000707; mean CPM = 53.66; phospholipase C, gamma 1" ID="ID_7530954" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIP5K1C: 1.27-fold Down; FDR = 0.00491; PValue = 0.00104; mean CPM = 37.75; phosphatidylinositol-4-phosphate 5-kinase, type I, gamma" ID="ID_91876816" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IMPA1: 1.31-fold Up; FDR = 0.00576; PValue = 0.00125; mean CPM = 21.96; inositol(myo)-1(or 4)-monophosphatase 1" ID="ID_1264183925" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DGKH: 1.25-fold Up; FDR = 0.0107; PValue = 0.00253; mean CPM = 39.42; diacylglycerol kinase, eta" ID="ID_1521023283" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DGKZ: 1.24-fold Down; FDR = 0.0116; PValue = 0.00278; mean CPM = 60.61; diacylglycerol kinase, zeta 104kDa" ID="ID_1488796971" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AC144536.2: 1.23-fold Down; FDR = 0.014; PValue = 0.00346; mean CPM = 58.91; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1 isoform 1" ID="ID_810247162" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INPP4B: 1.46-fold Down; FDR = 0.0151; PValue = 0.00378; mean CPM = 7.455; inositol polyphosphate-4-phosphatase, type II, 105kDa" ID="ID_1068645832" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INPP5D: 1.88-fold Down; FDR = 0.0276; PValue = 0.00763; mean CPM = 5.690; inositol polyphosphate-5-phosphatase, 145kDa" ID="ID_146665855" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDIPT: 1.21-fold Down; FDR = 0.0297; PValue = 0.00831; mean CPM = 71.76; CDP-diacylglycerol--inositol 3-phosphatidyltransferase" ID="ID_1994329735" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITPKC: 1.23-fold Down; FDR = 0.0389; PValue = 0.0114; mean CPM = 19.77; inositol 1,4,5-trisphosphate 3-kinase C" ID="ID_353048823" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SYNJ1: 1.25-fold Down; FDR = 0.0395; PValue = 0.0117; mean CPM = 23.44; synaptojanin 1" ID="ID_194695622" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INPPL1: 1.2-fold Down; FDR = 0.0395; PValue = 0.0117; mean CPM = 129.4; Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2; Uncharacterized protein" ID="ID_1247024771" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCB2: 3.68-fold Down; FDR = 0.0481; PValue = 0.0147; mean CPM = 1.557; Uncharacterized protein" ID="ID_358083493" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INPP1: 1.27-fold Up; FDR = 0.0742; PValue = 0.0246; mean CPM = 11.30; inositol polyphosphate-1-phosphatase" ID="ID_1891904318" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITPKA: 2.05-fold Up; FDR = 0.0744; PValue = 0.0247; mean CPM = 1.253; inositol 1,4,5-trisphosphate 3-kinase A" ID="ID_802564164" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IMPAD1: 1.17-fold Up; FDR = 0.0836; PValue = 0.0283; mean CPM = 81.94; inositol monophosphatase domain containing 1" ID="ID_386991206" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITPR2: 1.17-fold Up; FDR = 0.0872; PValue = 0.0297; mean CPM = 69.62; inositol 1,4,5-trisphosphate receptor, type 2" ID="ID_1877350138" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALM1: 1.18-fold Down; FDR = 0.104; PValue = 0.0368; mean CPM = 292.9; calmodulin 1 (phosphorylase kinase, delta)" ID="ID_856677758" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIKFYVE: 1.15-fold Up; FDR = 0.119; PValue = 0.0432; mean CPM = 67.91; phosphoinositide kinase, FYVE finger containing" ID="ID_300306602" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTEN: 1.14-fold Up; FDR = 0.166; PValue = 0.065; mean CPM = 89.60; phosphatase and tensin homolog" ID="ID_443591562" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITPR3: 1.13-fold Up; FDR = 0.194; PValue = 0.079; mean CPM = 157.4; inositol 1,4,5-triphosphate receptor, type 3" ID="ID_1056598525" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DGKE: 1.15-fold Up; FDR = 0.28; PValue = 0.124; mean CPM = 14.57; diacylglycerol kinase, epsilon 64kDa" ID="ID_1200709013" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DGKQ: 1.11-fold Down; FDR = 0.324; PValue = 0.149; mean CPM = 47.37; diacylglycerol kinase, theta 110kDa" ID="ID_1645274402" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_389437859" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALM1: 1.11-fold Up; FDR = 0.343; PValue = 0.16; mean CPM = 412.7; Calmodulin; Uncharacterized protein" ID="ID_758811678" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IMPA2: 1.13-fold Down; FDR = 0.346; PValue = 0.162; mean CPM = 18.15; inositol(myo)-1(or 4)-monophosphatase 2" ID="ID_643125869" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1410227298" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3C2B: 1.17-fold Down; FDR = 0.406; PValue = 0.198; mean CPM = 6.381; phosphoinositide-3-kinase, class 2, beta polypeptide" ID="ID_1669657795" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_700796778" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="OCRL: 1.07-fold Up; FDR = 0.571; PValue = 0.309; mean CPM = 60.28; Uncharacterized protein" ID="ID_1370148666" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMD4: 1.07-fold Up; FDR = 0.662; PValue = 0.377; mean CPM = 196.2; Macaca mulatta proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 (PSMD4), mRNA." ID="ID_1592316636" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PI4KB: 1.05-fold Down; FDR = 0.796; PValue = 0.493; mean CPM = 94.74; phosphatidylinositol 4-kinase, catalytic, beta" ID="ID_1900137724" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALML5: 1.49-fold Up; FDR = 0.819; PValue = 0.518; mean CPM = 0.8129; calmodulin-like 5" ID="ID_1508872975" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDS1: 1.23-fold Up; FDR = 0.886; PValue = 0.608; mean CPM = 0.9605; CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1" ID="ID_509625152" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALML6: 1.1-fold Up; FDR = 0.888; PValue = 0.61; mean CPM = 6.655; calmodulin-like 6" ID="ID_159814693" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALML3: 1.41-fold Down; FDR = 0.911; PValue = 0.698; mean CPM = 0.8159; calmodulin-like 3" ID="ID_665966676" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIP5K2B: 1.03-fold Up; FDR = 0.919; PValue = 0.72; mean CPM = 24.71; phosphatidylinositol-5-phosphate 4-kinase, type II, beta" ID="ID_1631456523" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INPP4A: 1.03-fold Up; FDR = 0.924; PValue = 0.73; mean CPM = 29.18; inositol polyphosphate-4-phosphatase, type I, 107kDa" ID="ID_1857143595" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3C2A: 1.02-fold Up; FDR = 0.957; PValue = 0.788; mean CPM = 84.41; phosphoinositide-3-kinase, class 2, alpha polypeptide" ID="ID_1738499576" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DGKB: 1.21-fold Down; FDR = 0.967; PValue = 0.806; mean CPM = 0.8318; diacylglycerol kinase, beta 90kDa" ID="ID_1977142322" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016883: 1.11-fold Down; FDR = 0.97; PValue = 0.811; mean CPM = 0.8838; Uncharacterized protein" ID="ID_1481364127" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PI4K2A: 1.02-fold Down; FDR = 0.973; PValue = 0.814; mean CPM = 18.77; phosphatidylinositol 4-kinase type 2 alpha" ID="ID_1383191931" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG2: 1.06-fold Up; FDR = 0.985; PValue = 0.834; mean CPM = 2.248; phospholipase C, gamma 2 (phosphatidylinositol-specific)" ID="ID_1374005708" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INPP5E: 1.02-fold Down; FDR = 1; PValue = 0.871; mean CPM = 15.47; inositol polyphosphate-5-phosphatase, 72 kDa" ID="ID_1270187229" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCZ1: 1.2-fold Down; FDR = 1; PValue = 0.95; mean CPM = 0.8210; phospholipase C, zeta 1" ID="ID_209142620" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Hippo signaling pathway: Inhibited, FDR = 0.081, FWER = 1, PValue = 0.0257" ID="ID_664157879" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="FGF1: 5.05-fold Down; FDR = 8.21e-14; PValue = 1.05e-15; mean CPM = 19.54; fibroblast growth factor 1 (acidic)" ID="ID_1795553102" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB3: 4.82-fold Down; FDR = 1.82e-12; PValue = 3.09e-14; mean CPM = 9.911; transforming growth factor, beta 3" ID="ID_1903760146" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD2: 2.27-fold Down; FDR = 5e-11; PValue = 1.24e-12; mean CPM = 20.66; frizzled homolog 2 (Drosophila)" ID="ID_1622566350" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTGF: 3.38-fold Down; FDR = 5e-11; PValue = 1.24e-12; mean CPM = 1595; connective tissue growth factor" ID="ID_939517466" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND3: 2.27-fold Down; FDR = 8.38e-11; PValue = 2.15e-12; mean CPM = 86.90; cyclin D3" ID="ID_892240578" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC2: 1.96-fold Up; FDR = 1.01e-10; PValue = 2.62e-12; mean CPM = 53.58; baculoviral IAP repeat-containing 2" ID="ID_57690903" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LLGL1: 1.54-fold Down; FDR = 1.11e-07; PValue = 6.26e-09; mean CPM = 44.37; Uncharacterized protein" ID="ID_1770544287" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NF2: 1.44-fold Down; FDR = 4.19e-06; PValue = 3.54e-07; mean CPM = 50.56; Uncharacterized protein" ID="ID_1390377238" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD7: 1.62-fold Down; FDR = 5.66e-06; PValue = 4.95e-07; mean CPM = 34.19; frizzled homolog 7 (Drosophila)" ID="ID_248438615" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GLI2: 2.04-fold Down; FDR = 8.71e-06; PValue = 8.1e-07; mean CPM = 14.39; GLI family zinc finger 2" ID="ID_1558238775" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT5A: 1.65-fold Down; FDR = 2.5e-05; PValue = 2.59e-06; mean CPM = 136.4; wingless-type MMTV integration site family, member 5A" ID="ID_497987220" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R1B: 1.39-fold Down; FDR = 4.37e-05; PValue = 4.86e-06; mean CPM = 233.1; protein phosphatase 2, regulatory subunit A, beta" ID="ID_1633396075" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000009315: 1.44-fold Down; FDR = 4.44e-05; PValue = 4.94e-06; mean CPM = 22.79" ID="ID_1472648496" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AXIN2: 3.75-fold Down; FDR = 6.09e-05; PValue = 7.1e-06; mean CPM = 2.690; axin 2" ID="ID_1958650168" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MPP5: 1.4-fold Down; FDR = 0.000161; PValue = 2.13e-05; mean CPM = 25.50; membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)" ID="ID_1575565161" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SCRIB: 1.37-fold Down; FDR = 0.000163; PValue = 2.15e-05; mean CPM = 68.59; scribbled homolog (Drosophila)" ID="ID_845942561" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2CB: 1.35-fold Up; FDR = 0.000215; PValue = 2.96e-05; mean CPM = 59.68; protein phosphatase 2, catalytic subunit, beta isozyme" ID="ID_234722481" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD9: 2.74-fold Down; FDR = 0.000408; PValue = 6.1e-05; mean CPM = 1.789; frizzled homolog 9 (Drosophila)" ID="ID_469105160" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000030553: 1.37-fold Down; FDR = 0.000429; PValue = 6.45e-05; mean CPM = 25.77; Uncharacterized protein" ID="ID_794649611" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R2B: 7.66-fold Down; FDR = 0.000564; PValue = 8.78e-05; mean CPM = 4.510; protein phosphatase 2, regulatory subunit B, beta" ID="ID_1185920342" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD3: 1.38-fold Up; FDR = 0.000573; PValue = 8.94e-05; mean CPM = 114.9; SMAD family member 3" ID="ID_1174065417" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AMOT: 1.68-fold Down; FDR = 0.000647; PValue = 0.000103; mean CPM = 6.991; Uncharacterized protein" ID="ID_1342338949" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT1: 7.1-fold Down; FDR = 0.000659; PValue = 0.000105; mean CPM = 2.664; wingless-type MMTV integration site family, member 1" ID="ID_1414422427" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WWTR1: 1.31-fold Down; FDR = 0.000801; PValue = 0.000131; mean CPM = 52.32; WW domain containing transcription regulator 1" ID="ID_153085979" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUB: 1.38-fold Up; FDR = 0.00112; PValue = 0.000192; mean CPM = 93.97; jub, ajuba homolog (Xenopus laevis)" ID="ID_1223903755" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DVL3: 1.29-fold Down; FDR = 0.00157; PValue = 0.00028; mean CPM = 67.95; dishevelled, dsh homolog 3 (Drosophila)" ID="ID_1940935657" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ID1: 1.64-fold Down; FDR = 0.00178; PValue = 0.000326; mean CPM = 22.90; inhibitor of DNA binding 1, dominant negative helix-loop-helix protein" ID="ID_1935920785" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GDF6: 2.38-fold Down; FDR = 0.00203; PValue = 0.000377; mean CPM = 5.258; growth differentiation factor 6" ID="ID_329679339" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SERPINE1: 1.58-fold Down; FDR = 0.00232; PValue = 0.000438; mean CPM = 5294; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1" ID="ID_148562205" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD4: 1.83-fold Up; FDR = 0.00258; PValue = 0.000495; mean CPM = 4.537; frizzled homolog 4 (Drosophila)" ID="ID_616088529" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BX276089.1: 1.28-fold Up; FDR = 0.00273; PValue = 0.000528; mean CPM = 45.56; Serine/threonine-protein kinase LATS1 (EC 2.7.11.1)(Large tumor suppressor homolog 1)(WARTS protein kinase)(h-warts)" ID="ID_1789254142" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LLGL2: 1.9-fold Down; FDR = 0.00316; PValue = 0.000624; mean CPM = 4.210; lethal giant larvae homolog 2 (Drosophila)" ID="ID_325320393" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000004158: 2.22-fold Down; FDR = 0.00368; PValue = 0.000746; mean CPM = 1.981; Uncharacterized protein" ID="ID_586533705" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD7: 1.33-fold Down; FDR = 0.00568; PValue = 0.00123; mean CPM = 67.59; SMAD family member 7" ID="ID_187200488" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT7A: 3.46-fold Down; FDR = 0.00638; PValue = 0.0014; mean CPM = 1.036; wingless-type MMTV integration site family, member 7A" ID="ID_39955189" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT10A: 4.08-fold Down; FDR = 0.00805; PValue = 0.00183; mean CPM = 0.9138; wingless-type MMTV integration site family, member 10A" ID="ID_1714000497" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BMP2: 2.5-fold Up; FDR = 0.00836; PValue = 0.00191; mean CPM = 3.220; bone morphogenetic protein 2" ID="ID_1191704372" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT5B: 1.58-fold Down; FDR = 0.00866; PValue = 0.002; mean CPM = 7.832; wingless-type MMTV integration site family, member 5B" ID="ID_335783387" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT10B: 3.1-fold Down; FDR = 0.0148; PValue = 0.00369; mean CPM = 1.086; wingless-type MMTV integration site family, member 10B" ID="ID_431342410" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TEAD4: 1.27-fold Up; FDR = 0.0149; PValue = 0.00373; mean CPM = 37.02; TEA domain family member 4" ID="ID_1080539039" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCZ: 1.51-fold Up; FDR = 0.0152; PValue = 0.00381; mean CPM = 10.46; protein kinase C, zeta" ID="ID_338726909" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB2: 1.55-fold Down; FDR = 0.0187; PValue = 0.00485; mean CPM = 34.87; Integrin beta" ID="ID_104963703" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000004160: 1.56-fold Down; FDR = 0.0331; PValue = 0.00947; mean CPM = 3.462; Uncharacterized protein" ID="ID_862126391" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD2: 1.2-fold Up; FDR = 0.034; PValue = 0.00976; mean CPM = 57.10; SMAD family member 2" ID="ID_420931707" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFBR1: 1.2-fold Up; FDR = 0.037; PValue = 0.0108; mean CPM = 90.92; transforming growth factor, beta receptor 1" ID="ID_1882479957" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TCF7: 1.72-fold Down; FDR = 0.0376; PValue = 0.011; mean CPM = 4.279; transcription factor 7 (T-cell specific, HMG-box)" ID="ID_1187105601" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTNNB1: 1.2-fold Up; FDR = 0.0498; PValue = 0.0153; mean CPM = 558.3; catenin (cadherin-associated protein), beta 1, 88kDa" ID="ID_68856920" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APC2: 1.29-fold Down; FDR = 0.0505; PValue = 0.0155; mean CPM = 8.899; adenomatosis polyposis coli 2" ID="ID_175954389" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT4: 1.52-fold Down; FDR = 0.0525; PValue = 0.0163; mean CPM = 13.66; wingless-type MMTV integration site family, member 4" ID="ID_1097307977" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="YWHAH: 1.18-fold Down; FDR = 0.057; PValue = 0.018; mean CPM = 69.27; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide" ID="ID_1291474303" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP53BP2: 1.18-fold Up; FDR = 0.0596; PValue = 0.019; mean CPM = 170.3; tumor protein p53 binding protein, 2" ID="ID_304081840" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP73: 2.3-fold Down; FDR = 0.0601; PValue = 0.0192; mean CPM = 1.058; tumor protein p73" ID="ID_1761212770" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFBR2: 1.19-fold Up; FDR = 0.0643; PValue = 0.0208; mean CPM = 350.8; transforming growth factor, beta receptor II (70/80kDa)" ID="ID_956900258" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_649851196" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TCF7L1: 1.2-fold Down; FDR = 0.0783; PValue = 0.0262; mean CPM = 25.11; transcription factor 7-like 1 (T-cell specific, HMG-box)" ID="ID_1635561605" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BMP6: 1.74-fold Down; FDR = 0.0895; PValue = 0.0307; mean CPM = 2.386; bone morphogenetic protein 6" ID="ID_763971716" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DLG2: 2.16-fold Down; FDR = 0.0934; PValue = 0.0323; mean CPM = 1.076; discs, large homolog 2 (Drosophila)" ID="ID_1608740184" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FBXW11: 1.16-fold Up; FDR = 0.106; PValue = 0.0378; mean CPM = 64.90; F-box and WD repeat domain containing 11" ID="ID_1542377833" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PARD6B: 1.35-fold Up; FDR = 0.109; PValue = 0.0389; mean CPM = 6.109; par-6 partitioning defective 6 homolog beta (C. elegans)" ID="ID_975451353" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BMP4: 1.86-fold Down; FDR = 0.119; PValue = 0.0432; mean CPM = 2.163; bone morphogenetic protein 4" ID="ID_881447490" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND1: 1.17-fold Up; FDR = 0.121; PValue = 0.0443; mean CPM = 867.3; cyclin D1" ID="ID_1763903636" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SNAI2: 1.27-fold Up; FDR = 0.127; PValue = 0.0468; mean CPM = 55.60; snail homolog 2 (Drosophila)" ID="ID_1888451615" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SAV1: 1.23-fold Up; FDR = 0.128; PValue = 0.0472; mean CPM = 20.36; salvador homolog 1 (Drosophila)" ID="ID_270837632" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC5: 1.51-fold Down; FDR = 0.134; PValue = 0.0501; mean CPM = 18.55; Baculoviral IAP repeat-containing protein 5 isoform 1; Uncharacterized protein" ID="ID_1870417495" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_825183584" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AREGB: 1.85-fold Up; FDR = 0.14; PValue = 0.053; mean CPM = 1.300; amphiregulin B" ID="ID_43344128" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000009838: 1.26-fold Down; FDR = 0.151; PValue = 0.0579; mean CPM = 6.141; Uncharacterized protein" ID="ID_139018211" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000009838: 1.26-fold Down; FDR = 0.151; PValue = 0.0579; mean CPM = 6.141; Uncharacterized protein" ID="ID_648655598" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PARD6A: 1.64-fold Up; FDR = 0.151; PValue = 0.0579; mean CPM = 1.554; par-6 partitioning defective 6 homolog alpha (C. elegans)" ID="ID_1055470523" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD1: 1.23-fold Down; FDR = 0.154; PValue = 0.0592; mean CPM = 31.65; frizzled homolog 1 (Drosophila)" ID="ID_1176998735" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NKD1: 2.25-fold Down; FDR = 0.161; PValue = 0.0628; mean CPM = 0.9036; naked cuticle homolog 1 (Drosophila)" ID="ID_486233474" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="YWHAG: 1.14-fold Down; FDR = 0.162; PValue = 0.0632; mean CPM = 175.7; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide" ID="ID_229584045" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BMPR1B: 1.73-fold Down; FDR = 0.18; PValue = 0.0718; mean CPM = 1.275; bone morphogenetic protein receptor, type IB" ID="ID_254191098" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000035840: 1.54-fold Down; FDR = 0.182; PValue = 0.0731; mean CPM = 1.666" ID="ID_23344268" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT3A: 2.28-fold Down; FDR = 0.2; PValue = 0.0823; mean CPM = 0.8811; wingless-type MMTV integration site family, member 3A" ID="ID_379891964" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="YWHAQ: 1.13-fold Up; FDR = 0.216; PValue = 0.0903; mean CPM = 187.3; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide" ID="ID_1580978581" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSNK1E: 1.13-fold Down; FDR = 0.221; PValue = 0.0928; mean CPM = 85.29; casein kinase 1, epsilon" ID="ID_311900142" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000004157: 1.47-fold Down; FDR = 0.291; PValue = 0.131; mean CPM = 1.576; Uncharacterized protein" ID="ID_8010246" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT3: 1.4-fold Up; FDR = 0.304; PValue = 0.138; mean CPM = 1.843; wingless-type MMTV integration site family, member 3" ID="ID_3737792" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND2: 1.2-fold Up; FDR = 0.335; PValue = 0.155; mean CPM = 76.91; cyclin D2" ID="ID_92355463" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD6: 1.11-fold Down; FDR = 0.347; PValue = 0.162; mean CPM = 39.10; frizzled homolog 6 (Drosophila)" ID="ID_325493028" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TEAD1: 1.1-fold Up; FDR = 0.357; PValue = 0.168; mean CPM = 91.86; TEA domain family member 1 (SV40 transcriptional enhancer factor)" ID="ID_1991843798" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APC: 1.1-fold Down; FDR = 0.367; PValue = 0.174; mean CPM = 127.5; adenomatous polyposis coli" ID="ID_1707595635" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSNK1D: 1.1-fold Down; FDR = 0.378; PValue = 0.18; mean CPM = 93.44; casein kinase 1, delta" ID="ID_118174923" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R2C: 1.48-fold Up; FDR = 0.391; PValue = 0.188; mean CPM = 1.318; protein phosphatase 2, regulatory subunit B, gamma" ID="ID_705744802" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD5: 1.34-fold Down; FDR = 0.405; PValue = 0.197; mean CPM = 2.107; frizzled homolog 5 (Drosophila)" ID="ID_1141514400" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BTRC: 1.11-fold Down; FDR = 0.413; PValue = 0.202; mean CPM = 17.40; beta-transducin repeat containing" ID="ID_541872040" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PARD6G: 1.48-fold Down; FDR = 0.498; PValue = 0.257; mean CPM = 1.086; par-6 partitioning defective 6 homolog gamma (C. elegans)" ID="ID_1178754193" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT9A: 1.43-fold Down; FDR = 0.505; PValue = 0.262; mean CPM = 2.172; wingless-type MMTV integration site family, member 9A" ID="ID_633141916" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MOB1A: 1.44-fold Up; FDR = 0.514; PValue = 0.268; mean CPM = 1.184; MOB kinase activator 1A" ID="ID_645893375" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCI: 1.08-fold Up; FDR = 0.518; PValue = 0.271; mean CPM = 47.99; protein kinase C, iota" ID="ID_1085736327" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP1CB: 1.08-fold Up; FDR = 0.566; PValue = 0.306; mean CPM = 108.6; protein phosphatase 1, catalytic subunit, beta isozyme" ID="ID_772583131" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PARD3: 1.07-fold Up; FDR = 0.581; PValue = 0.316; mean CPM = 129.4; par-3 partitioning defective 3 homolog (C. elegans)" ID="ID_1986372527" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT2B: 1.29-fold Down; FDR = 0.621; PValue = 0.345; mean CPM = 1.575; wingless-type MMTV integration site family, member 2B" ID="ID_317244469" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AXIN1: 1.06-fold Up; FDR = 0.661; PValue = 0.376; mean CPM = 66.56; axin 1" ID="ID_402286135" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LEF1: 1.2-fold Up; FDR = 0.691; PValue = 0.4; mean CPM = 2.488; lymphoid enhancer-binding factor 1" ID="ID_743472741" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DVL2: 1.06-fold Up; FDR = 0.708; PValue = 0.414; mean CPM = 30.54; dishevelled, dsh homolog 2 (Drosophila)" ID="ID_1898779065" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R2A: 1.06-fold Down; FDR = 0.733; PValue = 0.435; mean CPM = 44.53; protein phosphatase 2, regulatory subunit B, alpha" ID="ID_829228706" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LIMD1: 1.06-fold Up; FDR = 0.742; PValue = 0.443; mean CPM = 59.77; LIM domains containing 1" ID="ID_1977805754" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD1: 1.07-fold Up; FDR = 0.768; PValue = 0.466; mean CPM = 16.45; SMAD family member 1" ID="ID_1998067805" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASSF6: 1.45-fold Up; FDR = 0.773; PValue = 0.471; mean CPM = 0.8229; Ras association (RalGDS/AF-6) domain family member 6" ID="ID_1203796956" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="YWHAZ: 1.05-fold Down; FDR = 0.785; PValue = 0.482; mean CPM = 341.0; 14-3-3 protein zeta/delta; Uncharacterized protein" ID="ID_1033481097" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="YWHAE: 1.05-fold Up; FDR = 0.799; PValue = 0.496; mean CPM = 281.1; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide" ID="ID_1460164264" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2CA: 1.05-fold Up; FDR = 0.8; PValue = 0.497; mean CPM = 62.78; protein phosphatase 2, catalytic subunit, alpha isozyme" ID="ID_1379052065" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AFP: 1.39-fold Up; FDR = 0.841; PValue = 0.548; mean CPM = 0.8032; alpha-fetoprotein" ID="ID_522605433" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WWC1: 1.07-fold Down; FDR = 0.852; PValue = 0.564; mean CPM = 36.32; WW and C2 domain containing 1" ID="ID_1933295595" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT16: 1.27-fold Down; FDR = 0.857; PValue = 0.571; mean CPM = 0.9003; wingless-type MMTV integration site family, member 16" ID="ID_927751294" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ID2: 1.1-fold Up; FDR = 0.866; PValue = 0.582; mean CPM = 12.52; inhibitor of DNA binding 2, dominant negative helix-loop-helix protein" ID="ID_966744947" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="YWHAZ: 1.09-fold Up; FDR = 0.888; PValue = 0.61; mean CPM = 3.241; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide" ID="ID_540987634" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R2D: 1.04-fold Down; FDR = 0.899; PValue = 0.629; mean CPM = 19.98; protein phosphatase 2, regulatory subunit B, delta isoform" ID="ID_563766061" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT11: 1.18-fold Up; FDR = 0.903; PValue = 0.641; mean CPM = 1.340; wingless-type MMTV integration site family, member 11" ID="ID_1984907794" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BMPR1A: 1.04-fold Up; FDR = 0.903; PValue = 0.641; mean CPM = 36.13; bone morphogenetic protein receptor, type IA" ID="ID_226870420" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB2: 1.05-fold Down; FDR = 0.903; PValue = 0.655; mean CPM = 110.8; transforming growth factor, beta 2" ID="ID_989262756" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD4: 1.03-fold Down; FDR = 0.906; PValue = 0.666; mean CPM = 43.02; SMAD family member 4" ID="ID_168772735" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="YWHAB: 1.03-fold Up; FDR = 0.906; PValue = 0.672; mean CPM = 144.6; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide" ID="ID_1280850281" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LATS2: 1.03-fold Down; FDR = 0.911; PValue = 0.706; mean CPM = 162.6; LATS, large tumor suppressor, homolog 2 (Drosophila)" ID="ID_1502632310" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AMH: 1.35-fold Down; FDR = 0.914; PValue = 0.71; mean CPM = 0.8126; anti-Mullerian hormone" ID="ID_186866928" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FRMD1: 1.18-fold Down; FDR = 0.916; PValue = 0.717; mean CPM = 0.8173; FERM domain containing 1" ID="ID_143331435" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GDF5: 1.16-fold Down; FDR = 0.922; PValue = 0.726; mean CPM = 0.9185; growth differentiation factor 5" ID="ID_282064460" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB1: 1.02-fold Down; FDR = 0.936; PValue = 0.749; mean CPM = 62.61; transforming growth factor, beta 1" ID="ID_1712917723" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BBC3: 1.04-fold Down; FDR = 0.948; PValue = 0.77; mean CPM = 7.586; BCL2 binding component 3" ID="ID_503854721" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTNNA1: 1.02-fold Down; FDR = 0.971; PValue = 0.811; mean CPM = 553.3; Uncharacterized protein" ID="ID_1210697458" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT8B: 1.21-fold Down; FDR = 0.987; PValue = 0.838; mean CPM = 0.8506; wingless-type MMTV integration site family, member 8B" ID="ID_1321010009" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BMP5: 1.09-fold Up; FDR = 0.995; PValue = 0.851; mean CPM = 0.8780; bone morphogenetic protein 5" ID="ID_639477000" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASSF1: 1.01-fold Down; FDR = 1; PValue = 0.87; mean CPM = 87.09; Uncharacterized protein" ID="ID_1076492973" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT2: 1.07-fold Down; FDR = 1; PValue = 0.888; mean CPM = 0.8103; wingless-type MMTV integration site family member 2" ID="ID_796399941" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DLG1: 1.01-fold Up; FDR = 1; PValue = 0.888; mean CPM = 43.53; discs, large homolog 1 (Drosophila)" ID="ID_1677303347" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD3: 1.03-fold Up; FDR = 1; PValue = 0.903; mean CPM = 1.636; frizzled homolog 3 (Drosophila)" ID="ID_1125937416" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="YWHAE: 1.03-fold Up; FDR = 1; PValue = 0.911; mean CPM = 1.303; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon" ID="ID_559882485" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD10: 1.04-fold Down; FDR = 1; PValue = 0.919; mean CPM = 0.8435; frizzled homolog 10 (Drosophila)" ID="ID_1624156445" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT6: 1.13-fold Down; FDR = 1; PValue = 0.956; mean CPM = 0.8230; wingless-type MMTV integration site family, member 6" ID="ID_368088281" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BMPR2: No Change; FDR = 1; PValue = 0.974; mean CPM = 136.9; Bone morphogenetic protein receptor type-2; Uncharacterized protein" ID="ID_1555744921" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTNNA3: 1.02-fold Down; FDR = 1; PValue = 0.978; mean CPM = 0.7999; catenin (cadherin-associated protein), alpha 3" ID="ID_1566101671" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT9B: 1.03-fold Up; FDR = 1; PValue = 0.991; mean CPM = 0.8041; wingless-type MMTV integration site family, member 9B" ID="ID_1448846263" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BMP7: 1.01-fold Up; FDR = 1; PValue = 0.994; mean CPM = 0.8010; bone morphogenetic protein 7" ID="ID_1298718228" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="YAP1: No Change; FDR = 1; PValue = 0.997; mean CPM = 78.90; Yes-associated protein 1" ID="ID_1317232824" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOX2: No Change; FDR = 1; PValue = 1; mean CPM = 0.7808; SRY (sex determining region Y)-box 2" ID="ID_1222171555" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Apoptosis: Activated, FDR = 0.0938, FWER = 1, PValue = 0.0307" ID="ID_675336816" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_1312098058" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF10: 44.5-fold Up; FDR = 2.83e-16; PValue = 2.4e-18; mean CPM = 6.029; Tumor necrosis factor ligand superfamily member 10 isoform 1; Uncharacterized protein" ID="ID_547430084" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC2: 1.96-fold Up; FDR = 1.01e-10; PValue = 2.62e-12; mean CPM = 53.58; baculoviral IAP repeat-containing 2" ID="ID_1638753082" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CFLAR: 1.87-fold Up; FDR = 5.09e-10; PValue = 1.61e-11; mean CPM = 103.3; CASP8 and FADD-like apoptosis regulator" ID="ID_1295244024" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BID: 1.66-fold Up; FDR = 5.41e-09; PValue = 2.19e-10; mean CPM = 35.19; BH3 interacting domain death agonist" ID="ID_916105200" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_702264401" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK4: 1.8-fold Up; FDR = 3.31e-08; PValue = 1.64e-09; mean CPM = 12.89; interleukin-1 receptor-associated kinase 4" ID="ID_91138354" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1559234870" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_639054301" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1004924300" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L1: 1.51-fold Up; FDR = 9.13e-07; PValue = 6.52e-08; mean CPM = 66.15; Bcl-2-like protein 1; Bcl-2-like protein 1 isoform 1; Uncharacterized protein" ID="ID_1593945830" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_992255160" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_1458210745" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC3: 2.79-fold Up; FDR = 1.74e-06; PValue = 1.32e-07; mean CPM = 95.34; baculoviral IAP repeat-containing 3" ID="ID_1675770950" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKAR2A: 1.46-fold Down; FDR = 2.88e-05; PValue = 3.04e-06; mean CPM = 21.98; protein kinase, cAMP-dependent, regulatory, type II, alpha" ID="ID_1294623882" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1R1: 1.6-fold Up; FDR = 3.35e-05; PValue = 3.61e-06; mean CPM = 123.7; interleukin 1 receptor, type I" ID="ID_1728066517" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF10D: 1.84-fold Down; FDR = 5.9e-05; PValue = 6.84e-06; mean CPM = 32.06; tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain" ID="ID_111473748" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKAR2B: 1.54-fold Up; FDR = 0.000139; PValue = 1.8e-05; mean CPM = 22.70; protein kinase, cAMP-dependent, regulatory, type II, beta" ID="ID_1853925791" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACA: 1.36-fold Down; FDR = 0.000167; PValue = 2.22e-05; mean CPM = 37.75; protein kinase, cAMP-dependent, catalytic, alpha" ID="ID_1059211916" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP3CA: 1.55-fold Up; FDR = 0.0003; PValue = 4.32e-05; mean CPM = 40.21; protein phosphatase 3, catalytic subunit, alpha isozyme" ID="ID_1056780179" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAD: 1.36-fold Down; FDR = 0.000605; PValue = 9.52e-05; mean CPM = 48.46; BCL2-associated agonist of cell death" ID="ID_1507981392" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NGF: 1.32-fold Up; FDR = 0.00212; PValue = 0.000396; mean CPM = 198.5; nerve growth factor (beta polypeptide)" ID="ID_190088983" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKX: 1.31-fold Down; FDR = 0.00331; PValue = 0.000658; mean CPM = 24.94; protein kinase, X-linked" ID="ID_947880461" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_982271173" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK3: 1.54-fold Up; FDR = 0.00653; PValue = 0.00144; mean CPM = 19.97; interleukin-1 receptor-associated kinase 3" ID="ID_506368433" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K14: 1.47-fold Down; FDR = 0.00704; PValue = 0.00157; mean CPM = 9.470; mitogen-activated protein kinase kinase kinase 14" ID="ID_25008729" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP10: 1.81-fold Up; FDR = 0.0175; PValue = 0.0045; mean CPM = 2.876; caspase 10, apoptosis-related cysteine peptidase" ID="ID_64506900" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_613086900" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRADD: 1.22-fold Up; FDR = 0.0319; PValue = 0.00907; mean CPM = 34.75; TNFRSF1A-associated via death domain" ID="ID_1401206532" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_239107638" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1RAP: 1.35-fold Up; FDR = 0.0392; PValue = 0.0116; mean CPM = 10.66; interleukin 1 receptor accessory protein" ID="ID_1567885590" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DFFA: 1.18-fold Down; FDR = 0.0688; PValue = 0.0225; mean CPM = 44.03; DNA fragmentation factor, 45kDa, alpha polypeptide" ID="ID_943673646" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FADD: 1.18-fold Down; FDR = 0.0936; PValue = 0.0324; mean CPM = 30.89; Uncharacterized protein" ID="ID_108779194" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_712824124" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XIAP: 1.17-fold Up; FDR = 0.177; PValue = 0.0706; mean CPM = 19.21; X-linked inhibitor of apoptosis" ID="ID_118005891" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XIAP: 1.26-fold Up; FDR = 0.192; PValue = 0.0778; mean CPM = 5.625; Uncharacterized protein" ID="ID_411949953" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP6: 1.17-fold Up; FDR = 0.197; PValue = 0.0807; mean CPM = 14.25; caspase 6, apoptosis-related cysteine peptidase" ID="ID_241032577" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP7: 1.15-fold Up; FDR = 0.218; PValue = 0.0916; mean CPM = 21.49; caspase 7, apoptosis-related cysteine peptidase" ID="ID_1711257345" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000039103: 1.67-fold Down; FDR = 0.221; PValue = 0.0927; mean CPM = 1.310; Uncharacterized protein" ID="ID_1522244760" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK2: 1.27-fold Down; FDR = 0.259; PValue = 0.113; mean CPM = 10.13; interleukin-1 receptor-associated kinase 2" ID="ID_1213504814" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_996526883" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1A: 1.11-fold Up; FDR = 0.297; PValue = 0.134; mean CPM = 134.7; tumor necrosis factor receptor superfamily, member 1A" ID="ID_1146579740" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKAR1B: 1.29-fold Down; FDR = 0.306; PValue = 0.139; mean CPM = 3.719; protein kinase, cAMP-dependent, regulatory, type I, beta" ID="ID_1072238544" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1A: 1.5-fold Up; FDR = 0.315; PValue = 0.144; mean CPM = 155.4; interleukin 1, alpha" ID="ID_115262718" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_1669803588" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF10B: 1.13-fold Down; FDR = 0.343; PValue = 0.16; mean CPM = 40.59; tumor necrosis factor receptor superfamily, member 10b" ID="ID_437173329" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP53: 1.11-fold Down; FDR = 0.364; PValue = 0.172; mean CPM = 33.25; tumor protein p53" ID="ID_973921271" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1610560737" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2: 1.48-fold Up; FDR = 0.384; PValue = 0.184; mean CPM = 1.344; Uncharacterized protein" ID="ID_1018171721" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP3CB: 1.08-fold Up; FDR = 0.514; PValue = 0.268; mean CPM = 76.44; protein phosphatase 3, catalytic subunit, beta isozyme" ID="ID_24418564" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_1397768045" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_1714226974" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF10A: 1.06-fold Down; FDR = 0.732; PValue = 0.434; mean CPM = 42.75; tumor necrosis factor receptor superfamily, member 10a" ID="ID_1038659363" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_1783946526" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACG: 1.51-fold Down; FDR = 0.795; PValue = 0.491; mean CPM = 0.8026; protein kinase, cAMP-dependent, catalytic, gamma" ID="ID_1661224864" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAX: 1.05-fold Up; FDR = 0.809; PValue = 0.506; mean CPM = 162.4; Uncharacterized protein" ID="ID_150410218" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APAF1: 1.05-fold Down; FDR = 0.837; PValue = 0.543; mean CPM = 32.11; apoptotic peptidase activating factor 1" ID="ID_1893308426" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYCS: 1.05-fold Up; FDR = 0.854; PValue = 0.565; mean CPM = 93.43; cytochrome c, somatic" ID="ID_217699459" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_160715346" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000040219: 1.08-fold Up; FDR = 0.86; PValue = 0.575; mean CPM = 8.818; Uncharacterized protein" ID="ID_1411860006" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC7: 1.52-fold Down; FDR = 0.881; PValue = 0.601; mean CPM = 0.8439; baculoviral IAP repeat containing 7" ID="ID_1615620579" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK1: 1.04-fold Down; FDR = 0.885; PValue = 0.606; mean CPM = 41.54; interleukin-1 receptor-associated kinase 1" ID="ID_1850713239" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_49299020" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000035551: 1.1-fold Down; FDR = 0.892; PValue = 0.615; mean CPM = 2.529" ID="ID_1454590862" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000021684: 1.44-fold Up; FDR = 0.903; PValue = 0.662; mean CPM = 0.8513; Uncharacterized protein" ID="ID_635828214" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACB: 1.03-fold Up; FDR = 0.911; PValue = 0.694; mean CPM = 30.10; protein kinase, cAMP-dependent, catalytic, beta" ID="ID_223549949" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DFFB: 1.05-fold Down; FDR = 0.911; PValue = 0.699; mean CPM = 5.555; DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)" ID="ID_1297029339" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FASLG: 1.2-fold Down; FDR = 0.941; PValue = 0.757; mean CPM = 0.8088; Fas ligand (TNF superfamily, member 6)" ID="ID_1321209933" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000009289: 1.07-fold Up; FDR = 0.963; PValue = 0.798; mean CPM = 2.536; Uncharacterized protein" ID="ID_1071784300" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NTRK1: 1.07-fold Up; FDR = 0.977; PValue = 0.82; mean CPM = 1.195; neurotrophic tyrosine kinase, receptor, type 1" ID="ID_789790335" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKAR1A: 1.01-fold Up; FDR = 1; PValue = 0.867; mean CPM = 256.1; protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)" ID="ID_193621175" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL3: 1.17-fold Down; FDR = 1; PValue = 0.9; mean CPM = 0.8325; Macaca mulatta interleukin 3 (colony-stimulating factor, multiple) (IL3), mRNA." ID="ID_1169201262" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP9: 1.01-fold Up; FDR = 1; PValue = 0.908; mean CPM = 19.86; caspase 9, apoptosis-related cysteine peptidase" ID="ID_1813956544" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Glioma: Inhibited, FDR = 0.0938, FWER = 1, PValue = 0.0311" ID="ID_1084895827" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="PDGFRA: 2.76-fold Up; FDR = 3.93e-14; PValue = 4.67e-16; mean CPM = 492.9; platelet-derived growth factor receptor, alpha polypeptide" ID="ID_321398740" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC4: 7.09-fold Down; FDR = 1.82e-12; PValue = 3.1e-14; mean CPM = 6.421; SHC (Src homology 2 domain containing) family, member 4" ID="ID_1338961751" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_690993424" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGFR: 1.84-fold Up; FDR = 6.71e-09; PValue = 2.77e-10; mean CPM = 68.58; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)" ID="ID_127383063" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAMK2D: 1.54-fold Up; FDR = 4.06e-08; PValue = 2.07e-09; mean CPM = 51.52; calcium/calmodulin-dependent protein kinase II delta" ID="ID_196203546" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RB1: 1.65-fold Up; FDR = 6.01e-08; PValue = 3.2e-09; mean CPM = 59.24; retinoblastoma 1" ID="ID_1552223897" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFA: 1.92-fold Down; FDR = 2.56e-07; PValue = 1.58e-08; mean CPM = 22.99; platelet-derived growth factor alpha polypeptide" ID="ID_1844204122" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1730585316" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1829186808" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_882555371" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1: 5.76-fold Down; FDR = 6.73e-06; PValue = 6.04e-07; mean CPM = 1.536; insulin-like growth factor 1 (somatomedin C)" ID="ID_6397207" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1R: 1.51-fold Down; FDR = 1.02e-05; PValue = 9.61e-07; mean CPM = 213.2; insulin-like growth factor 1 receptor" ID="ID_964367430" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_580164316" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALM3: 1.41-fold Down; FDR = 0.000714; PValue = 0.000115; mean CPM = 94.24; calmodulin 3 (phosphorylase kinase, delta)" ID="ID_342391469" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTOR: 1.3-fold Down; FDR = 0.00117; PValue = 0.000201; mean CPM = 107.5; mechanistic target of rapamycin (serine/threonine kinase)" ID="ID_1745811417" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAMK2A: 2.29-fold Down; FDR = 0.00124; PValue = 0.000217; mean CPM = 2.001; calcium/calmodulin-dependent protein kinase II alpha" ID="ID_1331213245" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG1: 1.31-fold Down; FDR = 0.00352; PValue = 0.000707; mean CPM = 53.66; phospholipase C, gamma 1" ID="ID_910854681" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAMK2B: 3.82-fold Down; FDR = 0.00536; PValue = 0.00115; mean CPM = 1.542; calcium/calmodulin-dependent protein kinase II beta" ID="ID_1196795894" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MDM2: 1.32-fold Up; FDR = 0.00555; PValue = 0.00119; mean CPM = 148.6; Uncharacterized protein" ID="ID_163167356" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFB: 1.97-fold Down; FDR = 0.0133; PValue = 0.00326; mean CPM = 2.424; platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)" ID="ID_1410331349" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1851782152" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1753473525" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KRAS: 1.35-fold Down; FDR = 0.0401; PValue = 0.0119; mean CPM = 13.10; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog" ID="ID_1328642869" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="E2F1: 1.44-fold Down; FDR = 0.0425; PValue = 0.0127; mean CPM = 8.857; E2F transcription factor 1" ID="ID_1105131885" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NRAS: 1.2-fold Down; FDR = 0.0546; PValue = 0.017; mean CPM = 32.39; neuroblastoma RAS viral (v-ras) oncogene homolog" ID="ID_1356651615" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_499242820" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS2: 1.17-fold Up; FDR = 0.1; PValue = 0.0353; mean CPM = 31.79; son of sevenless homolog 2 (Drosophila)" ID="ID_20943777" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALM1: 1.18-fold Down; FDR = 0.104; PValue = 0.0368; mean CPM = 292.9; calmodulin 1 (phosphorylase kinase, delta)" ID="ID_1741081296" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND1: 1.17-fold Up; FDR = 0.121; PValue = 0.0443; mean CPM = 867.3; cyclin D1" ID="ID_359505588" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTEN: 1.14-fold Up; FDR = 0.166; PValue = 0.065; mean CPM = 89.60; phosphatase and tensin homolog" ID="ID_55072278" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC2: 1.34-fold Down; FDR = 0.191; PValue = 0.0774; mean CPM = 7.313; SHC (Src homology 2 domain containing) transforming protein 2" ID="ID_624137569" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1938141920" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_1811205628" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BRAF: 1.14-fold Down; FDR = 0.228; PValue = 0.0964; mean CPM = 24.98; v-raf murine sarcoma viral oncogene homolog B1" ID="ID_686093655" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1A: 1.16-fold Down; FDR = 0.28; PValue = 0.124; mean CPM = 363.2; Cyclin-dependent kinase inhibitor 1; Uncharacterized protein" ID="ID_1328397001" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_1193991811" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK6: 1.18-fold Down; FDR = 0.301; PValue = 0.136; mean CPM = 26.51; cyclin-dependent kinase 6" ID="ID_1375914563" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_130587123" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALM1: 1.11-fold Up; FDR = 0.343; PValue = 0.16; mean CPM = 412.7; Calmodulin; Uncharacterized protein" ID="ID_1094576456" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP53: 1.11-fold Down; FDR = 0.364; PValue = 0.172; mean CPM = 33.25; tumor protein p53" ID="ID_217440431" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_164388538" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_329060666" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_437270573" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC3: 1.37-fold Down; FDR = 0.584; PValue = 0.318; mean CPM = 1.193; SHC-transforming protein 3; Uncharacterized protein" ID="ID_1608965778" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCG: 1.47-fold Down; FDR = 0.609; PValue = 0.336; mean CPM = 0.9297; protein kinase C, gamma" ID="ID_630272477" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFA: 1.89-fold Up; FDR = 0.725; PValue = 0.428; mean CPM = 0.8701; transforming growth factor, alpha" ID="ID_728717664" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCB: 1.86-fold Up; FDR = 0.727; PValue = 0.43; mean CPM = 0.8705; protein kinase C, beta" ID="ID_143162627" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="E2F3: 1.08-fold Up; FDR = 0.751; PValue = 0.452; mean CPM = 11.79; E2F transcription factor 3" ID="ID_530259449" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALML5: 1.49-fold Up; FDR = 0.819; PValue = 0.518; mean CPM = 0.8129; calmodulin-like 5" ID="ID_882552865" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_74453533" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALML6: 1.1-fold Up; FDR = 0.888; PValue = 0.61; mean CPM = 6.655; calmodulin-like 6" ID="ID_1828259553" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK4: 1.04-fold Up; FDR = 0.899; PValue = 0.626; mean CPM = 65.45; cyclin-dependent kinase 4" ID="ID_1871625151" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALML3: 1.41-fold Down; FDR = 0.911; PValue = 0.698; mean CPM = 0.8159; calmodulin-like 3" ID="ID_1018580155" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_334724738" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016883: 1.11-fold Down; FDR = 0.97; PValue = 0.811; mean CPM = 0.8838; Uncharacterized protein" ID="ID_483785819" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG2: 1.06-fold Up; FDR = 0.985; PValue = 0.834; mean CPM = 2.248; phospholipase C, gamma 2 (phosphatidylinositol-specific)" ID="ID_315646300" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFRB: 1.01-fold Up; FDR = 1; PValue = 0.883; mean CPM = 391.1; platelet-derived growth factor receptor, beta polypeptide" ID="ID_1136670122" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGF: 1.06-fold Down; FDR = 1; PValue = 0.885; mean CPM = 0.8917; epidermal growth factor" ID="ID_819510966" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="E2F2: 1.03-fold Up; FDR = 1; PValue = 0.906; mean CPM = 1.976; E2F transcription factor 2" ID="ID_887176639" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg FoxO signaling pathway: Inhibited, FDR = 0.103, FWER = 1, PValue = 0.035" ID="ID_1175013792" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TNFSF10: 44.5-fold Up; FDR = 2.83e-16; PValue = 2.4e-18; mean CPM = 6.029; Tumor necrosis factor ligand superfamily member 10 isoform 1; Uncharacterized protein" ID="ID_1652746464" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB3: 4.82-fold Down; FDR = 1.82e-12; PValue = 3.09e-14; mean CPM = 9.911; transforming growth factor, beta 3" ID="ID_1389432821" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HOMER2: 3.03-fold Down; FDR = 1.06e-11; PValue = 2.22e-13; mean CPM = 20.33; homer homolog 2 (Drosophila)" ID="ID_412858906" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_336681014" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAT: 1.75-fold Up; FDR = 1.21e-09; PValue = 4.14e-11; mean CPM = 42.72; catalase" ID="ID_1926673291" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_1022429918" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGFR: 1.84-fold Up; FDR = 6.71e-09; PValue = 2.77e-10; mean CPM = 68.58; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)" ID="ID_352903447" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRS1: 2.78-fold Up; FDR = 7.67e-09; PValue = 3.19e-10; mean CPM = 26.55; Uncharacterized protein" ID="ID_389194782" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1B: 1.64-fold Up; FDR = 1.22e-08; PValue = 5.39e-10; mean CPM = 32.96; Cyclin-dependent kinase inhibitor 1B; Uncharacterized protein" ID="ID_629242668" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INSR: 1.93-fold Down; FDR = 1.24e-08; PValue = 5.48e-10; mean CPM = 118.3; insulin receptor" ID="ID_1270218737" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOD2: 4.88-fold Up; FDR = 1.73e-08; PValue = 7.93e-10; mean CPM = 558.4; superoxide dismutase 2, mitochondrial" ID="ID_1295660321" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNG2: 1.58-fold Up; FDR = 2.55e-07; PValue = 1.56e-08; mean CPM = 45.06; cyclin G2" ID="ID_1770458541" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1795484816" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATG12: 1.67-fold Up; FDR = 8.54e-07; PValue = 6.03e-08; mean CPM = 48.65; ATG12 autophagy related 12 homolog (S. cerevisiae)" ID="ID_522116467" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_572543123" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_465483733" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_384214469" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STK4: 1.47-fold Up; FDR = 3.87e-06; PValue = 3.24e-07; mean CPM = 35.55; serine/threonine kinase 4" ID="ID_1800352654" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKAA2: 1.7-fold Down; FDR = 5.6e-06; PValue = 4.89e-07; mean CPM = 11.23; protein kinase, AMP-activated, alpha 2 catalytic subunit" ID="ID_805459752" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1: 5.76-fold Down; FDR = 6.73e-06; PValue = 6.04e-07; mean CPM = 1.536; insulin-like growth factor 1 (somatomedin C)" ID="ID_54475210" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1R: 1.51-fold Down; FDR = 1.02e-05; PValue = 9.61e-07; mean CPM = 213.2; insulin-like growth factor 1 receptor" ID="ID_448025630" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKAG2: 1.62-fold Down; FDR = 1.04e-05; PValue = 9.84e-07; mean CPM = 16.27; protein kinase, AMP-activated, gamma 2 non-catalytic subunit" ID="ID_840812337" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1427790027" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLK1: 2.25-fold Down; FDR = 3.23e-05; PValue = 3.46e-06; mean CPM = 27.29; polo-like kinase 1 (Drosophila)" ID="ID_1092247146" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KLF2: 1.79-fold Down; FDR = 3.43e-05; PValue = 3.72e-06; mean CPM = 18.91; Uncharacterized protein" ID="ID_247754835" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PCK2: 1.8-fold Up; FDR = 8.33e-05; PValue = 1.01e-05; mean CPM = 110.4; phosphoenolpyruvate carboxykinase 2 (mitochondrial)" ID="ID_293812356" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="G6PC3: 1.37-fold Down; FDR = 0.000225; PValue = 3.11e-05; mean CPM = 33.42; glucose 6 phosphatase, catalytic, 3" ID="ID_1153159050" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD3: 1.38-fold Up; FDR = 0.000573; PValue = 8.94e-05; mean CPM = 114.9; SMAD family member 3" ID="ID_1974546503" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKAA1: 1.32-fold Up; FDR = 0.000825; PValue = 0.000135; mean CPM = 40.69; protein kinase, AMP-activated, alpha 1 catalytic subunit" ID="ID_1890278085" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN2B: 1.63-fold Down; FDR = 0.000936; PValue = 0.000156; mean CPM = 17.34; cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)" ID="ID_1538414343" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOXO1: 1.49-fold Down; FDR = 0.00109; PValue = 0.000186; mean CPM = 11.95; forkhead box O1" ID="ID_959892136" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HOMER3: 1.41-fold Down; FDR = 0.00127; PValue = 0.000222; mean CPM = 88.40; homer homolog 3 (Drosophila)" ID="ID_1740078162" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BNIP3: 1.38-fold Up; FDR = 0.00373; PValue = 0.000758; mean CPM = 169.1; BCL2/adenovirus E1B 19kDa interacting protein 3" ID="ID_1205254622" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SGK1: 1.36-fold Down; FDR = 0.0048; PValue = 0.00101; mean CPM = 395.0; Uncharacterized protein" ID="ID_1113808198" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_1442937041" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GADD45B: 1.49-fold Down; FDR = 0.0082; PValue = 0.00187; mean CPM = 175.6; growth arrest and DNA-damage-inducible, beta" ID="ID_1680119077" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GADD45G: 1.49-fold Up; FDR = 0.0173; PValue = 0.00444; mean CPM = 12.01; growth arrest and DNA-damage-inducible, gamma" ID="ID_45948055" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK2: 1.23-fold Down; FDR = 0.0194; PValue = 0.00507; mean CPM = 36.76; cyclin-dependent kinase 2" ID="ID_1542778427" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_358277992" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLK3: 1.27-fold Down; FDR = 0.0251; PValue = 0.00684; mean CPM = 26.43; polo-like kinase 3 (Drosophila)" ID="ID_1818280172" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_816710419" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD2: 1.2-fold Up; FDR = 0.034; PValue = 0.00976; mean CPM = 57.10; SMAD family member 2" ID="ID_437866048" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GADD45A: 1.22-fold Up; FDR = 0.0344; PValue = 0.00989; mean CPM = 127.8; growth arrest and DNA-damage-inducible, alpha" ID="ID_1135922429" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDPK1: 1.24-fold Down; FDR = 0.0361; PValue = 0.0105; mean CPM = 17.53; 3-phosphoinositide dependent protein kinase-1" ID="ID_1296784369" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GABARAP: 1.21-fold Up; FDR = 0.0367; PValue = 0.0107; mean CPM = 143.6; GABA(A) receptor-associated protein" ID="ID_1437503337" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFBR1: 1.2-fold Up; FDR = 0.037; PValue = 0.0108; mean CPM = 90.92; transforming growth factor, beta receptor 1" ID="ID_1953755567" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KRAS: 1.35-fold Down; FDR = 0.0401; PValue = 0.0119; mean CPM = 13.10; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog" ID="ID_887080154" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOXO4: 1.28-fold Down; FDR = 0.0401; PValue = 0.0119; mean CPM = 12.01; forkhead box O4" ID="ID_53238212" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NRAS: 1.2-fold Down; FDR = 0.0546; PValue = 0.017; mean CPM = 32.39; neuroblastoma RAS viral (v-ras) oncogene homolog" ID="ID_1896956031" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L11: 1.34-fold Up; FDR = 0.0609; PValue = 0.0195; mean CPM = 18.38; BCL2-like 11 (apoptosis facilitator)" ID="ID_1299389208" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFBR2: 1.19-fold Up; FDR = 0.0643; PValue = 0.0208; mean CPM = 350.8; transforming growth factor, beta receptor II (70/80kDa)" ID="ID_1649648060" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL7R: 1.76-fold Down; FDR = 0.0698; PValue = 0.0229; mean CPM = 3.067; interleukin 7 receptor" ID="ID_887385859" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_1757100305" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLK2: 1.18-fold Up; FDR = 0.0802; PValue = 0.0269; mean CPM = 123.0; polo-like kinase 2 (Drosophila)" ID="ID_242410270" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HOMER1: 1.24-fold Up; FDR = 0.0804; PValue = 0.027; mean CPM = 12.20; homer homolog 1 (Drosophila)" ID="ID_673166751" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SGK3: 1.34-fold Up; FDR = 0.0916; PValue = 0.0316; mean CPM = 5.230; serum/glucocorticoid regulated kinase family, member 3" ID="ID_1448725963" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNB1: 1.39-fold Down; FDR = 0.0958; PValue = 0.0333; mean CPM = 44.87; cyclin B1" ID="ID_7320785" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS2: 1.17-fold Up; FDR = 0.1; PValue = 0.0353; mean CPM = 31.79; son of sevenless homolog 2 (Drosophila)" ID="ID_896705518" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AGAP2: 1.55-fold Up; FDR = 0.106; PValue = 0.0377; mean CPM = 2.136; ArfGAP with GTPase domain, ankyrin repeat and PH domain 2" ID="ID_1943273147" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_908225961" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND1: 1.17-fold Up; FDR = 0.121; PValue = 0.0443; mean CPM = 867.3; cyclin D1" ID="ID_1073439325" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_1523788138" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="S1PR1: 1.9-fold Up; FDR = 0.132; PValue = 0.0492; mean CPM = 1.481; Uncharacterized protein" ID="ID_1012400290" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FBXO25: 1.19-fold Up; FDR = 0.162; PValue = 0.0633; mean CPM = 14.00; F-box protein 25" ID="ID_207344412" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTEN: 1.14-fold Up; FDR = 0.166; PValue = 0.065; mean CPM = 89.60; phosphatase and tensin homolog" ID="ID_1810198173" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GABARAPL2: 1.15-fold Up; FDR = 0.17; PValue = 0.0673; mean CPM = 34.90; GABA(A) receptor-associated protein-like 2" ID="ID_1957908403" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1488877765" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSNK1E: 1.13-fold Down; FDR = 0.221; PValue = 0.0928; mean CPM = 85.29; casein kinase 1, epsilon" ID="ID_1044780490" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SGK2: 2.06-fold Down; FDR = 0.225; PValue = 0.0952; mean CPM = 0.9494; serum/glucocorticoid regulated kinase 2" ID="ID_1897207452" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BRAF: 1.14-fold Down; FDR = 0.228; PValue = 0.0964; mean CPM = 24.98; v-raf murine sarcoma viral oncogene homolog B1" ID="ID_795775296" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNB2: 1.24-fold Down; FDR = 0.237; PValue = 0.101; mean CPM = 15.12; cyclin B2" ID="ID_584080846" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1A: 1.16-fold Down; FDR = 0.28; PValue = 0.124; mean CPM = 363.2; Cyclin-dependent kinase inhibitor 1; Uncharacterized protein" ID="ID_1948789010" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_1521083386" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKAB1: 1.12-fold Up; FDR = 0.3; PValue = 0.136; mean CPM = 30.19; protein kinase, AMP-activated, beta 1 non-catalytic subunit" ID="ID_148188419" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_399714131" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND2: 1.2-fold Up; FDR = 0.335; PValue = 0.155; mean CPM = 76.91; cyclin D2" ID="ID_1478066084" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRMT1: 1.11-fold Down; FDR = 0.34; PValue = 0.158; mean CPM = 156.5; protein arginine methyltransferase 1" ID="ID_600961977" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKAG1: 1.1-fold Up; FDR = 0.365; PValue = 0.173; mean CPM = 52.15; Uncharacterized protein" ID="ID_1261710338" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1222594889" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_1323758866" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1062208413" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK12: 1.19-fold Down; FDR = 0.422; PValue = 0.208; mean CPM = 6.569; mitogen-activated protein kinase 12" ID="ID_1360230503" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RBL2: 1.09-fold Up; FDR = 0.445; PValue = 0.222; mean CPM = 47.90; retinoblastoma-like 2 (p130)" ID="ID_1158850334" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_230207257" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SETD7: 1.08-fold Up; FDR = 0.51; PValue = 0.265; mean CPM = 61.63; SET domain containing (lysine methyltransferase) 7" ID="ID_1555778876" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_669583450" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK13: 1.22-fold Down; FDR = 0.536; PValue = 0.284; mean CPM = 3.100; mitogen-activated protein kinase 13" ID="ID_250604922" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOXO3: 1.08-fold Down; FDR = 0.55; PValue = 0.294; mean CPM = 48.45; forkhead box O3" ID="ID_622536813" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000025249: 1.12-fold Up; FDR = 0.68; PValue = 0.391; mean CPM = 5.019; Uncharacterized protein" ID="ID_1911247720" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FBXO32: 1.08-fold Down; FDR = 0.69; PValue = 0.399; mean CPM = 206.8; F-box protein 32" ID="ID_822340872" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRM1: 1.8-fold Down; FDR = 0.771; PValue = 0.469; mean CPM = 0.8322; glutamate receptor, metabotropic 1" ID="ID_1162522704" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKAB2: 1.07-fold Down; FDR = 0.809; PValue = 0.505; mean CPM = 10.04; protein kinase, AMP-activated, beta 2 non-catalytic subunit" ID="ID_384035255" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAG1: 1.32-fold Down; FDR = 0.835; PValue = 0.539; mean CPM = 0.8030; recombination activating gene 1" ID="ID_1384953926" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL6: 1.06-fold Down; FDR = 0.837; PValue = 0.542; mean CPM = 64.49; B-cell CLL/lymphoma 6" ID="ID_265390492" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1896196284" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1616097417" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRS4: 1.51-fold Down; FDR = 0.885; PValue = 0.606; mean CPM = 0.8400; insulin receptor substrate 4" ID="ID_1953706135" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB2: 1.05-fold Down; FDR = 0.903; PValue = 0.655; mean CPM = 110.8; transforming growth factor, beta 2" ID="ID_991387043" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD4: 1.03-fold Down; FDR = 0.906; PValue = 0.666; mean CPM = 43.02; SMAD family member 4" ID="ID_412027766" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLK4: 1.05-fold Up; FDR = 0.925; PValue = 0.731; mean CPM = 13.24; polo-like kinase 4 (Drosophila)" ID="ID_698892749" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="G6PC: 1.22-fold Down; FDR = 0.929; PValue = 0.737; mean CPM = 0.8105; glucose-6-phosphatase, catalytic subunit" ID="ID_168064122" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB1: 1.02-fold Down; FDR = 0.936; PValue = 0.749; mean CPM = 62.61; transforming growth factor, beta 1" ID="ID_463984583" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FASLG: 1.2-fold Down; FDR = 0.941; PValue = 0.757; mean CPM = 0.8088; Fas ligand (TNF superfamily, member 6)" ID="ID_1608232879" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_234533480" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGF: 1.06-fold Down; FDR = 1; PValue = 0.885; mean CPM = 0.8917; epidermal growth factor" ID="ID_826027187" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STK11: 1.01-fold Up; FDR = 1; PValue = 0.918; mean CPM = 47.98; serine/threonine kinase 11" ID="ID_913940933" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PCK1: 1.05-fold Down; FDR = 1; PValue = 0.961; mean CPM = 0.8008; phosphoenolpyruvate carboxykinase 1 (soluble)" ID="ID_593075529" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN2D: 1.01-fold Up; FDR = 1; PValue = 0.963; mean CPM = 4.277; cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)" ID="ID_1790249424" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL10: 1.21-fold Down; FDR = 1; PValue = 0.964; mean CPM = 0.8614; interleukin 10" ID="ID_1824768141" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLK: No Change; FDR = 1; PValue = 0.97; mean CPM = 11.78; nemo-like kinase" ID="ID_1700218985" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="S1PR4: 1.01-fold Up; FDR = 1; PValue = 0.976; mean CPM = 0.8190; sphingosine-1-phosphate receptor 4" ID="ID_1688736168" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAG2: 1.01-fold Down; FDR = 1; PValue = 0.989; mean CPM = 0.8003; Uncharacterized protein" ID="ID_652551351" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="G6PC2: No Change; FDR = 1; PValue = 1; mean CPM = 0.7816; glucose-6-phosphatase, catalytic, 2" ID="ID_72571814" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Vasopressin-regulated water reabsorption: Inhibited, FDR = 0.118, FWER = 1, PValue = 0.0407" ID="ID_1139487690" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CREB3L2: 2.11-fold Down; FDR = 5.05e-12; PValue = 9.78e-14; mean CPM = 64.33; cAMP responsive element binding protein 3-like 2" ID="ID_755752944" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY6: 1.89-fold Down; FDR = 1.9e-10; PValue = 5.38e-12; mean CPM = 141.3; adenylate cyclase 6" ID="ID_1071662294" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3L1: 1.99-fold Down; FDR = 1.52e-09; PValue = 5.36e-11; mean CPM = 211.4; cAMP responsive element binding protein 3-like 1" ID="ID_1890171888" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARHGDIA: 1.49-fold Down; FDR = 3.61e-06; PValue = 3.01e-07; mean CPM = 257.2; Rho GDP dissociation inhibitor (GDI) alpha" ID="ID_1334069280" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACA: 1.36-fold Down; FDR = 0.000167; PValue = 2.22e-05; mean CPM = 37.75; protein kinase, cAMP-dependent, catalytic, alpha" ID="ID_887037597" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB5: 2.1-fold Down; FDR = 0.000248; PValue = 3.48e-05; mean CPM = 4.269; cAMP responsive element binding protein 5" ID="ID_107720640" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STX4: 1.32-fold Up; FDR = 0.00111; PValue = 0.000191; mean CPM = 32.39; syntaxin 4" ID="ID_1209712500" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAS1: 1.31-fold Down; FDR = 0.00158; PValue = 0.000283; mean CPM = 564.9; Uncharacterized protein" ID="ID_585666788" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKX: 1.31-fold Down; FDR = 0.00331; PValue = 0.000658; mean CPM = 24.94; protein kinase, X-linked" ID="ID_109593775" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY9: 1.32-fold Down; FDR = 0.00986; PValue = 0.00231; mean CPM = 84.04; adenylate cyclase 9" ID="ID_1205609221" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB1: 1.21-fold Up; FDR = 0.0313; PValue = 0.00884; mean CPM = 36.07; cAMP responsive element binding protein 1" ID="ID_1570812902" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3L4: 1.3-fold Down; FDR = 0.0961; PValue = 0.0334; mean CPM = 6.034; cAMP responsive element binding protein 3-like 4" ID="ID_1545405495" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARHGDIB: 2.5-fold Down; FDR = 0.124; PValue = 0.0456; mean CPM = 1.180; Rho GDP dissociation inhibitor (GDI) beta" ID="ID_495370942" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3: 1.15-fold Up; FDR = 0.128; PValue = 0.0472; mean CPM = 167.9; cAMP responsive element binding protein 3" ID="ID_563252629" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACG: 1.51-fold Down; FDR = 0.795; PValue = 0.491; mean CPM = 0.8026; protein kinase, cAMP-dependent, catalytic, gamma" ID="ID_1080345754" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AQP2: 1.18-fold Down; FDR = 0.903; PValue = 0.661; mean CPM = 0.7909; aquaporin 2 (collecting duct)" ID="ID_293716968" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000021684: 1.44-fold Up; FDR = 0.903; PValue = 0.662; mean CPM = 0.8513; Uncharacterized protein" ID="ID_1976166144" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3L3: 1.4-fold Down; FDR = 0.908; PValue = 0.679; mean CPM = 0.8407; cAMP responsive element binding protein 3-like 3" ID="ID_966833315" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACB: 1.03-fold Up; FDR = 0.911; PValue = 0.694; mean CPM = 30.10; protein kinase, cAMP-dependent, catalytic, beta" ID="ID_1896472385" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY3: 1.01-fold Up; FDR = 1; PValue = 0.871; mean CPM = 34.92; adenylate cyclase 3" ID="ID_1660380389" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- </node>
- </node>
- <node TEXT="CAMERA gene set test" ID="ID_242302177" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="biocarta gene set collection" ID="ID_1357105852" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="graphite/biocarta ifn gamma signaling pathway: Upregulated, FDR = 0.206, PValue = 0.00152" ID="ID_363007095" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_165408636" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1925960919" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR1: 1.31-fold Up; FDR = 0.00151; PValue = 0.000268; mean CPM = 37.77; interferon gamma receptor 1" ID="ID_1956274759" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_673452218" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_1519239092" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/biocarta ifn alpha signaling pathway: Upregulated, FDR = 0.206, PValue = 0.00176" ID="ID_949363843" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="STAT2: 2.67-fold Up; FDR = 8.02e-19; PValue = 4.03e-21; mean CPM = 185.6; signal transducer and activator of transcription 2, 113kDa" ID="ID_1115821354" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1997389988" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR2: 1.74-fold Up; FDR = 1.85e-06; PValue = 1.44e-07; mean CPM = 26.05; interferon (alpha, beta and omega) receptor 2" ID="ID_892057755" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR1: 1.27-fold Up; FDR = 0.0101; PValue = 0.00237; mean CPM = 82.39; Uncharacterized protein" ID="ID_1267009035" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYK2: 1.24-fold Down; FDR = 0.0142; PValue = 0.00354; mean CPM = 42.58; tyrosine kinase 2" ID="ID_406112095" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ST13: 1.18-fold Up; FDR = 0.0609; PValue = 0.0195; mean CPM = 202.1; suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)" ID="ID_602592130" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_1511584599" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNB1: 1.79-fold Up; FDR = 0.731; PValue = 0.433; mean CPM = 0.8526; interferon, beta 1, fibroblast" ID="ID_967071629" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA1: No Change; FDR = 1; PValue = 0.998; mean CPM = 0.8014; interferon, alpha 1" ID="ID_64875904" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/biocarta platelet amyloid precursor protein pathway: Downregulated, FDR = 0.297, PValue = 0.00451" ID="ID_433739735" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="COL4A1: 7.03-fold Down; FDR = 1.47e-15; PValue = 1.34e-17; mean CPM = 3419; collagen, type IV, alpha 1" ID="ID_639562323" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLAU: 3.37-fold Down; FDR = 1.56e-10; PValue = 4.33e-12; mean CPM = 18.78; plasminogen activator, urokinase" ID="ID_1146879498" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL4A5: 2.03-fold Down; FDR = 3.06e-06; PValue = 2.48e-07; mean CPM = 9.810; collagen, type IV, alpha 5" ID="ID_531826273" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SERPINE1: 1.58-fold Down; FDR = 0.00232; PValue = 0.000438; mean CPM = 5294; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1" ID="ID_1518012765" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APP: 1.22-fold Up; FDR = 0.0273; PValue = 0.00755; mean CPM = 619.2; amyloid beta (A4) precursor protein" ID="ID_1347934393" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLAT: 1.37-fold Down; FDR = 0.034; PValue = 0.00976; mean CPM = 76.44; plasminogen activator, tissue" ID="ID_605154546" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL4A3: 1.67-fold Down; FDR = 0.422; PValue = 0.207; mean CPM = 0.9315; collagen, type IV, alpha 3 (Goodpasture antigen)" ID="ID_267308250" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL4A6: 1.4-fold Down; FDR = 0.631; PValue = 0.353; mean CPM = 1.078; collagen, type IV, alpha 6" ID="ID_1802226841" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="F9: 1.57-fold Down; FDR = 0.788; PValue = 0.485; mean CPM = 0.8079; coagulation factor IX" ID="ID_1994876668" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLG: 1.41-fold Down; FDR = 0.937; PValue = 0.751; mean CPM = 0.8390; plasminogen" ID="ID_410049608" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/biocarta egf signaling pathway: Upregulated, FDR = 0.297, PValue = 0.00507" ID="ID_1397654434" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_506071578" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_1679158929" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_267122545" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGFR: 1.84-fold Up; FDR = 6.71e-09; PValue = 2.77e-10; mean CPM = 68.58; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)" ID="ID_862248278" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1176604349" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_370306719" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1284252314" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_1644354304" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG1: 1.31-fold Down; FDR = 0.00352; PValue = 0.000707; mean CPM = 53.66; phospholipase C, gamma 1" ID="ID_466431113" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_1850373333" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_1291409494" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_14592882" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_326744019" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASA1: 1.03-fold Down; FDR = 0.909; PValue = 0.69; mean CPM = 103.7; Ras GTPase-activating protein 1 isoform 1; Uncharacterized protein" ID="ID_238670998" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_25970722" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGF: 1.06-fold Down; FDR = 1; PValue = 0.885; mean CPM = 0.8917; epidermal growth factor" ID="ID_555410734" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/biocarta fas signaling pathway (cd95): Upregulated, FDR = 0.315, PValue = 0.00913" ID="ID_1637117116" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_667371741" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK2: 3.75-fold Up; FDR = 6.1e-16; PValue = 5.38e-18; mean CPM = 68.21; receptor-interacting serine-threonine kinase 2" ID="ID_1446377162" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CFLAR: 1.87-fold Up; FDR = 5.09e-10; PValue = 1.61e-11; mean CPM = 103.3; CASP8 and FADD-like apoptosis regulator" ID="ID_1444891292" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RB1: 1.65-fold Up; FDR = 6.01e-08; PValue = 3.2e-09; mean CPM = 59.24; retinoblastoma 1" ID="ID_1716686157" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_894250430" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1181855021" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN13: 1.56-fold Up; FDR = 2.3e-05; PValue = 2.36e-06; mean CPM = 63.69; protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)" ID="ID_1997808896" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_175496898" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP10: 1.81-fold Up; FDR = 0.0175; PValue = 0.0045; mean CPM = 2.876; caspase 10, apoptosis-related cysteine peptidase" ID="ID_98901323" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FADD: 1.18-fold Down; FDR = 0.0936; PValue = 0.0324; mean CPM = 30.89; Uncharacterized protein" ID="ID_1820493491" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK2: 1.15-fold Up; FDR = 0.134; PValue = 0.0502; mean CPM = 89.49; p21 protein (Cdc42/Rac)-activated kinase 2" ID="ID_845284327" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP7: 1.15-fold Up; FDR = 0.218; PValue = 0.0916; mean CPM = 21.49; caspase 7, apoptosis-related cysteine peptidase" ID="ID_780432201" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_1863929344" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKDC: 1.03-fold Down; FDR = 0.909; PValue = 0.69; mean CPM = 376.4; protein kinase, DNA-activated, catalytic polypeptide" ID="ID_1603012174" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK1: 1.03-fold Down; FDR = 0.911; PValue = 0.705; mean CPM = 18.65; p21 protein (Cdc42/Rac)-activated kinase 1" ID="ID_1537632295" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FASLG: 1.2-fold Down; FDR = 0.941; PValue = 0.757; mean CPM = 0.8088; Fas ligand (TNF superfamily, member 6)" ID="ID_1528365483" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_569754791" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FAF1: 1.02-fold Down; FDR = 0.98; PValue = 0.824; mean CPM = 24.68; Fas (TNFRSF6) associated factor 1" ID="ID_1427993754" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_202663823" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DAXX: No Change; FDR = 1; PValue = 0.984; mean CPM = 106.5; Death domain-associated protein 6 (Daxx)(hDaxx)(Fas death domain-associated protein)(ETS1-associated protein 1)(EAP1)" ID="ID_152249872" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/biocarta antigen processing and presentation: Upregulated, FDR = 0.315, PValue = 0.00928" ID="ID_487478097" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CD74: 104-fold Up; FDR = 6e-17; PValue = 4.54e-19; mean CPM = 141.5; CD74 molecule, major histocompatibility complex, class II invariant chain" ID="ID_280640777" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DRB: 1.28-fold Up; FDR = 0.898; PValue = 0.624; mean CPM = 0.8112; MHC class II antigen; Uncharacterized protein" ID="ID_1344117430" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/biocarta inhibition of cellular proliferation by gleevec: Upregulated, FDR = 0.315, PValue = 0.0098" ID="ID_324151134" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_806342475" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1161371569" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_143888953" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_914828232" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_67433673" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1544932975" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_879080368" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1034749448" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_1272036426" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_886380721" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_542785112" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1268955048" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1340030392" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRKL: 1.11-fold Up; FDR = 0.371; PValue = 0.176; mean CPM = 34.10; v-crk sarcoma virus CT10 oncogene homolog (avian)-like" ID="ID_1292480424" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2: 1.48-fold Up; FDR = 0.384; PValue = 0.184; mean CPM = 1.344; Uncharacterized protein" ID="ID_536597256" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_550538855" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCR: 1.2-fold Down; FDR = 0.687; PValue = 0.397; mean CPM = 1.982; breakpoint cluster region" ID="ID_127965181" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_428648748" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_1434716086" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/biocarta bone remodeling: Upregulated, FDR = 0.315, PValue = 0.0123" ID="ID_1154002178" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="IRF9: 3.85-fold Up; FDR = 2.6e-19; PValue = 1.12e-21; mean CPM = 106.4; interferon regulatory factor 9" ID="ID_1409985288" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR2: 1.74-fold Up; FDR = 1.85e-06; PValue = 1.44e-07; mean CPM = 26.05; interferon (alpha, beta and omega) receptor 2" ID="ID_846036631" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_49989193" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR1: 1.27-fold Up; FDR = 0.0101; PValue = 0.00237; mean CPM = 82.39; Uncharacterized protein" ID="ID_1164646053" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_904277996" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF11: 1.8-fold Up; FDR = 0.039; PValue = 0.0115; mean CPM = 2.535; tumor necrosis factor (ligand) superfamily, member 11" ID="ID_1894571836" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOSL2: 1.14-fold Down; FDR = 0.154; PValue = 0.0594; mean CPM = 163.5; FOS-like antigen 2" ID="ID_79611630" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF11A: 1.4-fold Down; FDR = 0.676; PValue = 0.388; mean CPM = 0.9723; tumor necrosis factor receptor superfamily, member 11a, NFKB activator" ID="ID_1410330919" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNB1: 1.79-fold Up; FDR = 0.731; PValue = 0.433; mean CPM = 0.8526; interferon, beta 1, fibroblast" ID="ID_1681387655" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOSL1: 1.04-fold Up; FDR = 0.903; PValue = 0.657; mean CPM = 64.19; FOS-like antigen 1" ID="ID_922154304" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/biocarta tpo signaling pathway: Upregulated, FDR = 0.315, PValue = 0.0127" ID="ID_1006633114" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_334824703" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_689518003" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_54442569" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_167550158" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1783958536" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_749599010" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG1: 1.31-fold Down; FDR = 0.00352; PValue = 0.000707; mean CPM = 53.66; phospholipase C, gamma 1" ID="ID_332541960" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_794412292" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_1577234780" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_103677384" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_694886800" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_1727655265" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MPL: 1.3-fold Down; FDR = 0.411; PValue = 0.201; mean CPM = 2.108; myeloproliferative leukemia virus oncogene" ID="ID_333872038" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1326294865" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THPO: 1.38-fold Down; FDR = 0.756; PValue = 0.456; mean CPM = 0.8964; thrombopoietin" ID="ID_1038659749" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASA1: 1.03-fold Down; FDR = 0.909; PValue = 0.69; mean CPM = 103.7; Ras GTPase-activating protein 1 isoform 1; Uncharacterized protein" ID="ID_1928160830" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_1905083291" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/biocarta ß-arrestins in gpcr desensitization: Downregulated, FDR = 0.315, PValue = 0.0135" ID="ID_895273706" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="DNM1: 1.84-fold Down; FDR = 4.11e-11; PValue = 1.01e-12; mean CPM = 19.55; dynamin 1" ID="ID_163885799" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADRBK1: 1.5-fold Down; FDR = 3.36e-06; PValue = 2.76e-07; mean CPM = 46.25; adrenergic, beta, receptor kinase 1" ID="ID_1159390258" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAS1: 1.31-fold Down; FDR = 0.00158; PValue = 0.000283; mean CPM = 564.9; Uncharacterized protein" ID="ID_1338682524" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARRB1: 1.35-fold Down; FDR = 0.107; PValue = 0.0382; mean CPM = 4.106; arrestin, beta 1" ID="ID_1420136012" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNB1: 1.08-fold Down; FDR = 0.565; PValue = 0.305; mean CPM = 299.4; guanine nucleotide binding protein (G protein), beta polypeptide 1" ID="ID_1243008564" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNGT1: 1.05-fold Up; FDR = 1; PValue = 0.871; mean CPM = 0.8362; guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1" ID="ID_1286169818" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/biocarta overview of telomerase rna component gene hterc transcriptional regulation: Upregulated, FDR = 0.452, PValue = 0.0236" ID="ID_745577026" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="RB1: 1.65-fold Up; FDR = 6.01e-08; PValue = 3.2e-09; mean CPM = 59.24; retinoblastoma 1" ID="ID_271278238" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SP3: 1.43-fold Up; FDR = 4.44e-06; PValue = 3.78e-07; mean CPM = 94.44; Sp3 transcription factor" ID="ID_1183212691" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SP1: 1.23-fold Up; FDR = 0.0139; PValue = 0.00344; mean CPM = 75.49; Transcription factor Sp1 isoform a; Uncharacterized protein" ID="ID_326740216" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFYA: 1.14-fold Up; FDR = 0.174; PValue = 0.069; mean CPM = 34.54; nuclear transcription factor Y, alpha" ID="ID_59456125" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFYB: 1.1-fold Up; FDR = 0.547; PValue = 0.292; mean CPM = 15.90; nuclear transcription factor Y, beta" ID="ID_948178794" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/biocarta mechanisms of transcriptional repression by dna methylation: Upregulated, FDR = 0.452, PValue = 0.024" ID="ID_1445787763" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="SAP30: 2.14-fold Up; FDR = 6.14e-08; PValue = 3.28e-09; mean CPM = 10.69; Histone deacetylase complex subunit SAP30; Uncharacterized protein" ID="ID_1250456501" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MBD2: 1.43-fold Up; FDR = 4.85e-06; PValue = 4.16e-07; mean CPM = 67.19; methyl-CpG binding domain protein 2" ID="ID_1736522464" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SAP18: 1.3-fold Up; FDR = 0.00125; PValue = 0.000218; mean CPM = 100.9; Sin3A-associated protein, 18kDa" ID="ID_1171239817" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC1: 1.25-fold Up; FDR = 0.0159; PValue = 0.00403; mean CPM = 27.51; histone deacetylase 1" ID="ID_1357071575" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MBD3: 1.22-fold Down; FDR = 0.0194; PValue = 0.0051; mean CPM = 52.96; methyl-CpG binding domain protein 3" ID="ID_1476822595" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RBBP4: 1.19-fold Up; FDR = 0.0513; PValue = 0.0159; mean CPM = 52.35; retinoblastoma binding protein 4" ID="ID_792042436" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC2: 1.15-fold Up; FDR = 0.115; PValue = 0.0414; mean CPM = 93.64; histone deacetylase 2" ID="ID_664196898" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MECP2: 1.16-fold Up; FDR = 0.137; PValue = 0.0516; mean CPM = 26.72; methyl CpG binding protein 2 (Rett syndrome)" ID="ID_1004949844" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTA2: No Change; FDR = 1; PValue = 0.998; mean CPM = 79.29; metastasis associated 1 family, member 2" ID="ID_36535750" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/biocarta b cell survival pathway: Downregulated, FDR = 0.452, PValue = 0.0255" ID="ID_1769565449" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="LAMC1: 2.28-fold Down; FDR = 6.46e-13; PValue = 1.01e-14; mean CPM = 812.1; laminin, gamma 1 (formerly LAMB2)" ID="ID_100512271" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016591: 4.2-fold Down; FDR = 1.3e-11; PValue = 2.78e-13; mean CPM = 34.90; Uncharacterized protein" ID="ID_1517015331" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016587: 4.92-fold Down; FDR = 1.6e-11; PValue = 3.5e-13; mean CPM = 51.70; Uncharacterized protein" ID="ID_907577270" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_1449274317" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1438146929" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMC2: 2.28-fold Down; FDR = 9.83e-06; PValue = 9.24e-07; mean CPM = 16.99; laminin, gamma 2" ID="ID_1806954684" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB2: 1.48-fold Down; FDR = 0.000398; PValue = 5.93e-05; mean CPM = 695.6; laminin, beta 2 (laminin S)" ID="ID_1043900461" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTOR: 1.3-fold Down; FDR = 0.00117; PValue = 0.000201; mean CPM = 107.5; mechanistic target of rapamycin (serine/threonine kinase)" ID="ID_1496942415" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_449728651" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDPK1: 1.24-fold Down; FDR = 0.0361; PValue = 0.0105; mean CPM = 17.53; 3-phosphoinositide dependent protein kinase-1" ID="ID_1567151784" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB1: 1.23-fold Up; FDR = 0.0759; PValue = 0.0253; mean CPM = 2700; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)" ID="ID_1616068432" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMA4: 1.2-fold Down; FDR = 0.0793; PValue = 0.0266; mean CPM = 624.4; laminin, alpha 4" ID="ID_1399941910" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DPF2: 1.16-fold Down; FDR = 0.114; PValue = 0.0409; mean CPM = 49.07; D4, zinc and double PHD fingers family 2" ID="ID_922031422" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC5: 1.51-fold Down; FDR = 0.134; PValue = 0.0501; mean CPM = 18.55; Baculoviral IAP repeat-containing protein 5 isoform 1; Uncharacterized protein" ID="ID_1457266549" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP7: 1.15-fold Up; FDR = 0.218; PValue = 0.0916; mean CPM = 21.49; caspase 7, apoptosis-related cysteine peptidase" ID="ID_52640598" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014969: 1.93-fold Down; FDR = 0.303; PValue = 0.137; mean CPM = 0.9384; Uncharacterized protein" ID="ID_1249069361" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB3: 1.6-fold Down; FDR = 0.303; PValue = 0.137; mean CPM = 1.445; laminin, beta 3" ID="ID_1885493789" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA1: 1.1-fold Down; FDR = 0.57; PValue = 0.308; mean CPM = 422.3; integrin, alpha 1" ID="ID_347268803" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014966: 1.43-fold Down; FDR = 0.72; PValue = 0.423; mean CPM = 0.9009; Uncharacterized protein" ID="ID_1062674742" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_1212843673" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/biocarta hiv-1 nef: negative effector of fas and tnf: Upregulated, FDR = 0.452, PValue = 0.0274" ID="ID_504631340" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_1137184636" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CFLAR: 1.87-fold Up; FDR = 5.09e-10; PValue = 1.61e-11; mean CPM = 103.3; CASP8 and FADD-like apoptosis regulator" ID="ID_1222555121" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BID: 1.66-fold Up; FDR = 5.41e-09; PValue = 2.19e-10; mean CPM = 35.19; BH3 interacting domain death agonist" ID="ID_872811442" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_1695007290" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_697670945" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC3: 2.79-fold Up; FDR = 1.74e-06; PValue = 1.32e-07; mean CPM = 95.34; baculoviral IAP repeat-containing 3" ID="ID_1033745017" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_690690800" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF1: 2.6-fold Down; FDR = 1.48e-05; PValue = 1.46e-06; mean CPM = 20.19; TNF receptor-associated factor 1" ID="ID_1668354111" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAG4: 1.32-fold Up; FDR = 0.00191; PValue = 0.000353; mean CPM = 25.62; BCL2-associated athanogene 4" ID="ID_1648725053" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K14: 1.47-fold Down; FDR = 0.00704; PValue = 0.00157; mean CPM = 9.470; mitogen-activated protein kinase kinase kinase 14" ID="ID_366194583" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRADD: 1.22-fold Up; FDR = 0.0319; PValue = 0.00907; mean CPM = 34.75; TNFRSF1A-associated via death domain" ID="ID_1441830389" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FADD: 1.18-fold Down; FDR = 0.0936; PValue = 0.0324; mean CPM = 30.89; Uncharacterized protein" ID="ID_1634981888" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP6: 1.17-fold Up; FDR = 0.197; PValue = 0.0807; mean CPM = 14.25; caspase 6, apoptosis-related cysteine peptidase" ID="ID_468646994" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP7: 1.15-fold Up; FDR = 0.218; PValue = 0.0916; mean CPM = 21.49; caspase 7, apoptosis-related cysteine peptidase" ID="ID_1999947419" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000039103: 1.67-fold Down; FDR = 0.221; PValue = 0.0927; mean CPM = 1.310; Uncharacterized protein" ID="ID_1240955671" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2: 1.48-fold Up; FDR = 0.384; PValue = 0.184; mean CPM = 1.344; Uncharacterized protein" ID="ID_891816669" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K5: 1.21-fold Down; FDR = 0.6; PValue = 0.33; mean CPM = 8.023; mitogen-activated protein kinase kinase kinase 5" ID="ID_1034719039" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_1215108005" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRADD: 1.1-fold Down; FDR = 0.827; PValue = 0.527; mean CPM = 3.992; CASP2 and RIPK1 domain containing adaptor with death domain" ID="ID_14603576" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APAF1: 1.05-fold Down; FDR = 0.837; PValue = 0.543; mean CPM = 32.11; apoptotic peptidase activating factor 1" ID="ID_1612888177" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYCS: 1.05-fold Up; FDR = 0.854; PValue = 0.565; mean CPM = 93.43; cytochrome c, somatic" ID="ID_794437477" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_499303479" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000040219: 1.08-fold Up; FDR = 0.86; PValue = 0.575; mean CPM = 8.818; Uncharacterized protein" ID="ID_1938687803" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_855768073" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP2: 1.05-fold Up; FDR = 0.906; PValue = 0.667; mean CPM = 12.88; caspase 2, apoptosis-related cysteine peptidase" ID="ID_922686182" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FASLG: 1.2-fold Down; FDR = 0.941; PValue = 0.757; mean CPM = 0.8088; Fas ligand (TNF superfamily, member 6)" ID="ID_67922584" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000009289: 1.07-fold Up; FDR = 0.963; PValue = 0.798; mean CPM = 2.536; Uncharacterized protein" ID="ID_1995325184" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP9: 1.01-fold Up; FDR = 1; PValue = 0.908; mean CPM = 19.86; caspase 9, apoptosis-related cysteine peptidase" ID="ID_813731014" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DAXX: No Change; FDR = 1; PValue = 0.984; mean CPM = 106.5; Death domain-associated protein 6 (Daxx)(hDaxx)(Fas death domain-associated protein)(ETS1-associated protein 1)(EAP1)" ID="ID_505140557" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/biocarta il-7 signal transduction: Upregulated, FDR = 0.452, PValue = 0.029" ID="ID_1418146550" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="NMI: 6.35-fold Up; FDR = 1.04e-21; PValue = 2.78e-24; mean CPM = 42.95; N-myc (and STAT) interactor" ID="ID_134810341" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2B: 3.54-fold Up; FDR = 1.24e-07; PValue = 7.07e-09; mean CPM = 5.971; PTK2B protein tyrosine kinase 2 beta" ID="ID_1386529736" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_306951658" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK3: 2.31-fold Up; FDR = 0.00186; PValue = 0.000342; mean CPM = 2.154; Janus kinase 3" ID="ID_571481178" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FYN: 1.22-fold Up; FDR = 0.0156; PValue = 0.00393; mean CPM = 92.94; FYN oncogene related to SRC, FGR, YES" ID="ID_777683437" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA2B: 1.71-fold Down; FDR = 0.0187; PValue = 0.00486; mean CPM = 2.655; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)" ID="ID_1571302225" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_476906445" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EP300: 1.11-fold Up; FDR = 0.312; PValue = 0.142; mean CPM = 162.8; E1A binding protein p300" ID="ID_1808930537" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2: 1.48-fold Up; FDR = 0.384; PValue = 0.184; mean CPM = 1.344; Uncharacterized protein" ID="ID_1636166125" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREBBP: 1.01-fold Down; FDR = 0.993; PValue = 0.847; mean CPM = 137.7; CREB binding protein" ID="ID_29590637" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/biocarta the prc2 complex sets long-term gene silencing through modification of histone tails: Upregulated, FDR = 0.455, PValue = 0.0311" ID="ID_504452461" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="EZH2: 2.05-fold Up; FDR = 4.94e-08; PValue = 2.57e-09; mean CPM = 24.23; enhancer of zeste homolog 2 (Drosophila)" ID="ID_401558919" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CBX4: 1.72-fold Up; FDR = 1.66e-05; PValue = 1.65e-06; mean CPM = 46.38; chromobox homolog 4" ID="ID_1396096963" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BMI1: 1.45-fold Up; FDR = 0.00813; PValue = 0.00185; mean CPM = 24.38; BMI1 polycomb ring finger oncogene" ID="ID_1969427603" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SUZ12: 1.27-fold Up; FDR = 0.0131; PValue = 0.00321; mean CPM = 24.49; suppressor of zeste 12 homolog pseudogene" ID="ID_22070605" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC1: 1.25-fold Up; FDR = 0.0159; PValue = 0.00403; mean CPM = 27.51; histone deacetylase 1" ID="ID_1267719628" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RBBP4: 1.19-fold Up; FDR = 0.0513; PValue = 0.0159; mean CPM = 52.35; retinoblastoma binding protein 4" ID="ID_1338251259" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC2: 1.15-fold Up; FDR = 0.115; PValue = 0.0414; mean CPM = 93.64; histone deacetylase 2" ID="ID_1528114751" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RING1: 1.14-fold Down; FDR = 0.155; PValue = 0.0598; mean CPM = 54.55; ring finger protein 1" ID="ID_1390098745" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/biocarta pdgf signaling pathway: Upregulated, FDR = 0.462, PValue = 0.0343" ID="ID_1766476709" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_465088867" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFRA: 2.76-fold Up; FDR = 3.93e-14; PValue = 4.67e-16; mean CPM = 492.9; platelet-derived growth factor receptor, alpha polypeptide" ID="ID_163369388" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_1387132822" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SRF: 1.69-fold Down; FDR = 8.07e-11; PValue = 2.06e-12; mean CPM = 34.61; serum response factor (c-fos serum response element-binding transcription factor)" ID="ID_1873215698" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_1835845758" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFA: 1.92-fold Down; FDR = 2.56e-07; PValue = 1.58e-08; mean CPM = 22.99; platelet-derived growth factor alpha polypeptide" ID="ID_657494027" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_827700751" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_155924000" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_883707193" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_864715831" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG1: 1.31-fold Down; FDR = 0.00352; PValue = 0.000707; mean CPM = 53.66; phospholipase C, gamma 1" ID="ID_967585990" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_1193205301" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_684851355" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_1404789086" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_976403298" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_965404483" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_922874304" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_668832495" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASA1: 1.03-fold Down; FDR = 0.909; PValue = 0.69; mean CPM = 103.7; Ras GTPase-activating protein 1 isoform 1; Uncharacterized protein" ID="ID_1416819851" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_1865348334" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_884907894" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/biocarta sodd/tnfr1 signaling pathway: Upregulated, FDR = 0.462, PValue = 0.0386" ID="ID_297548212" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_772025618" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC3: 2.79-fold Up; FDR = 1.74e-06; PValue = 1.32e-07; mean CPM = 95.34; baculoviral IAP repeat-containing 3" ID="ID_1196299934" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAG4: 1.32-fold Up; FDR = 0.00191; PValue = 0.000353; mean CPM = 25.62; BCL2-associated athanogene 4" ID="ID_816614314" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRADD: 1.22-fold Up; FDR = 0.0319; PValue = 0.00907; mean CPM = 34.75; TNFRSF1A-associated via death domain" ID="ID_356921306" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MADD: 1.07-fold Up; FDR = 0.642; PValue = 0.361; mean CPM = 37.35; MAP-kinase activating death domain" ID="ID_1864895817" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRADD: 1.1-fold Down; FDR = 0.827; PValue = 0.527; mean CPM = 3.992; CASP2 and RIPK1 domain containing adaptor with death domain" ID="ID_1309746579" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_1057475521" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/biocarta ceramide signaling pathway: Upregulated, FDR = 0.462, PValue = 0.0412" ID="ID_1761834149" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_326071603" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_1181282084" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1057039498" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NSMAF: 1.71-fold Up; FDR = 6.03e-08; PValue = 3.21e-09; mean CPM = 45.18; neutral sphingomyelinase (N-SMase) activation associated factor" ID="ID_495446157" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC3: 2.79-fold Up; FDR = 1.74e-06; PValue = 1.32e-07; mean CPM = 95.34; baculoviral IAP repeat-containing 3" ID="ID_225449110" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1708409849" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMPD1: 1.47-fold Down; FDR = 1.4e-05; PValue = 1.36e-06; mean CPM = 113.1; sphingomyelin phosphodiesterase 1, acid lysosomal" ID="ID_1477210996" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1956580649" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP4K4: 1.4-fold Down; FDR = 3.08e-05; PValue = 3.27e-06; mean CPM = 242.8; mitogen-activated protein kinase kinase kinase kinase 4" ID="ID_508517322" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_1504720647" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAD: 1.36-fold Down; FDR = 0.000605; PValue = 9.52e-05; mean CPM = 48.46; BCL2-associated agonist of cell death" ID="ID_1361996775" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAG4: 1.32-fold Up; FDR = 0.00191; PValue = 0.000353; mean CPM = 25.62; BCL2-associated athanogene 4" ID="ID_575183838" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_980314084" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRADD: 1.22-fold Up; FDR = 0.0319; PValue = 0.00907; mean CPM = 34.75; TNFRSF1A-associated via death domain" ID="ID_1558248116" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FADD: 1.18-fold Down; FDR = 0.0936; PValue = 0.0324; mean CPM = 30.89; Uncharacterized protein" ID="ID_1900110722" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000039103: 1.67-fold Down; FDR = 0.221; PValue = 0.0927; mean CPM = 1.310; Uncharacterized protein" ID="ID_1443395427" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AIFM1: 1.12-fold Down; FDR = 0.251; PValue = 0.109; mean CPM = 46.82; apoptosis-inducing factor, mitochondrion-associated, 1" ID="ID_1873245190" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2: 1.48-fold Up; FDR = 0.384; PValue = 0.184; mean CPM = 1.344; Uncharacterized protein" ID="ID_1619179111" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_914585161" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MADD: 1.07-fold Up; FDR = 0.642; PValue = 0.361; mean CPM = 37.35; MAP-kinase activating death domain" ID="ID_1562322958" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAX: 1.05-fold Up; FDR = 0.809; PValue = 0.506; mean CPM = 162.4; Uncharacterized protein" ID="ID_510700267" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRADD: 1.1-fold Down; FDR = 0.827; PValue = 0.527; mean CPM = 3.992; CASP2 and RIPK1 domain containing adaptor with death domain" ID="ID_1830010324" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYCS: 1.05-fold Up; FDR = 0.854; PValue = 0.565; mean CPM = 93.43; cytochrome c, somatic" ID="ID_227006497" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000040219: 1.08-fold Up; FDR = 0.86; PValue = 0.575; mean CPM = 8.818; Uncharacterized protein" ID="ID_1010625272" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1883898464" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_1699334419" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_1175134068" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000009289: 1.07-fold Up; FDR = 0.963; PValue = 0.798; mean CPM = 2.536; Uncharacterized protein" ID="ID_580579602" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_424810101" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/biocarta regulators of bone mineralization: Downregulated, FDR = 0.462, PValue = 0.0437" ID="ID_1449732497" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="COL4A1: 7.03-fold Down; FDR = 1.47e-15; PValue = 1.34e-17; mean CPM = 3419; collagen, type IV, alpha 1" ID="ID_1225175925" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL4A5: 2.03-fold Down; FDR = 3.06e-06; PValue = 2.48e-07; mean CPM = 9.810; collagen, type IV, alpha 5" ID="ID_1177066823" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IBSP: 2.51-fold Down; FDR = 0.128; PValue = 0.0476; mean CPM = 0.8896; integrin-binding sialoprotein" ID="ID_156038801" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENPP1: 1.2-fold Down; FDR = 0.346; PValue = 0.162; mean CPM = 147.6; ectonucleotide pyrophosphatase/phosphodiesterase 1" ID="ID_486557369" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL4A3: 1.67-fold Down; FDR = 0.422; PValue = 0.207; mean CPM = 0.9315; collagen, type IV, alpha 3 (Goodpasture antigen)" ID="ID_121478273" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ALPL: 1.27-fold Up; FDR = 0.625; PValue = 0.348; mean CPM = 2.290; alkaline phosphatase, liver/bone/kidney" ID="ID_252725805" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL4A6: 1.4-fold Down; FDR = 0.631; PValue = 0.353; mean CPM = 1.078; collagen, type IV, alpha 6" ID="ID_1346990494" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/biocarta rho cell motility signaling pathway: Downregulated, FDR = 0.462, PValue = 0.0451" ID="ID_1540750143" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="VCL: 2.48-fold Down; FDR = 5.94e-13; PValue = 9.16e-15; mean CPM = 1013; vinculin" ID="ID_1891809441" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYLK: 2.29-fold Down; FDR = 1.02e-06; PValue = 7.45e-08; mean CPM = 128.3; myosin light chain kinase" ID="ID_853569894" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHOA: 1.28-fold Down; FDR = 0.00295; PValue = 0.000575; mean CPM = 277.8; ras homolog gene family, member A" ID="ID_1158954249" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP1R12B: 1.52-fold Down; FDR = 0.00383; PValue = 0.000782; mean CPM = 15.41; protein phosphatase 1, regulatory (inhibitor) subunit 12B" ID="ID_649492012" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLN1: 1.26-fold Down; FDR = 0.0101; PValue = 0.00238; mean CPM = 1820; talin 1" ID="ID_1633267353" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSN: 1.22-fold Down; FDR = 0.0305; PValue = 0.0086; mean CPM = 1017; gelsolin" ID="ID_1242506484" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PFN1: 1.12-fold Down; FDR = 0.337; PValue = 0.156; mean CPM = 965.8; profilin 1" ID="ID_1822759354" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMD4: 1.07-fold Up; FDR = 0.662; PValue = 0.377; mean CPM = 196.2; Macaca mulatta proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 (PSMD4), mRNA." ID="ID_318396041" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYL2: 1.15-fold Up; FDR = 0.909; PValue = 0.69; mean CPM = 0.7911; myosin, light chain 2, regulatory, cardiac, slow" ID="ID_1781512200" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/biocarta ucalpain and friends in cell spread: Downregulated, FDR = 0.462, PValue = 0.0454" ID="ID_1505141306" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="LAMC1: 2.28-fold Down; FDR = 6.46e-13; PValue = 1.01e-14; mean CPM = 812.1; laminin, gamma 1 (formerly LAMB2)" ID="ID_1338946011" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016591: 4.2-fold Down; FDR = 1.3e-11; PValue = 2.78e-13; mean CPM = 34.90; Uncharacterized protein" ID="ID_1073388306" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016587: 4.92-fold Down; FDR = 1.6e-11; PValue = 3.5e-13; mean CPM = 51.70; Uncharacterized protein" ID="ID_731055823" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMC2: 2.28-fold Down; FDR = 9.83e-06; PValue = 9.24e-07; mean CPM = 16.99; laminin, gamma 2" ID="ID_1171338934" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAPNS1: 1.4-fold Down; FDR = 6.09e-05; PValue = 7.11e-06; mean CPM = 239.1; calpain, small subunit 1" ID="ID_1778089128" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACTA1: 5.36-fold Down; FDR = 0.000251; PValue = 3.52e-05; mean CPM = 5.880; Uncharacterized protein" ID="ID_1225956885" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB2: 1.48-fold Down; FDR = 0.000398; PValue = 5.93e-05; mean CPM = 695.6; laminin, beta 2 (laminin S)" ID="ID_1589283000" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EZR: 1.32-fold Up; FDR = 0.00112; PValue = 0.000192; mean CPM = 426.3; Uncharacterized protein" ID="ID_1960227652" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHOA: 1.28-fold Down; FDR = 0.00295; PValue = 0.000575; mean CPM = 277.8; ras homolog gene family, member A" ID="ID_1944501877" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLN1: 1.26-fold Down; FDR = 0.0101; PValue = 0.00238; mean CPM = 1820; talin 1" ID="ID_1217821172" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB1: 1.23-fold Up; FDR = 0.0759; PValue = 0.0253; mean CPM = 2700; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)" ID="ID_763385277" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMA4: 1.2-fold Down; FDR = 0.0793; PValue = 0.0266; mean CPM = 624.4; laminin, alpha 4" ID="ID_798134039" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014969: 1.93-fold Down; FDR = 0.303; PValue = 0.137; mean CPM = 0.9384; Uncharacterized protein" ID="ID_901364667" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB3: 1.6-fold Down; FDR = 0.303; PValue = 0.137; mean CPM = 1.445; laminin, beta 3" ID="ID_1129627756" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2: 1.1-fold Up; FDR = 0.394; PValue = 0.191; mean CPM = 102.5; PTK2 protein tyrosine kinase 2" ID="ID_807011099" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA1: 1.1-fold Down; FDR = 0.57; PValue = 0.308; mean CPM = 422.3; integrin, alpha 1" ID="ID_1799398852" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014966: 1.43-fold Down; FDR = 0.72; PValue = 0.423; mean CPM = 0.9009; Uncharacterized protein" ID="ID_1017434819" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_479011826" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPTAN1: 1.01-fold Up; FDR = 1; PValue = 0.881; mean CPM = 946.2; spectrin, alpha, non-erythrocytic 1" ID="ID_195350031" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/biocarta angiotensin ii mediated activation of jnk pathway via pyk2 dependent signaling: Upregulated, FDR = 0.462, PValue = 0.0476" ID="ID_1763083386" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_700990958" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGFR: 1.84-fold Up; FDR = 6.71e-09; PValue = 2.77e-10; mean CPM = 68.58; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)" ID="ID_1262975024" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2B: 3.54-fold Up; FDR = 1.24e-07; PValue = 7.07e-09; mean CPM = 5.971; PTK2B protein tyrosine kinase 2 beta" ID="ID_1151277136" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1378973393" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_296701800" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCAR1: 1.36-fold Up; FDR = 0.000193; PValue = 2.61e-05; mean CPM = 210.4; breast cancer anti-estrogen resistance 1" ID="ID_26849207" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF2: 1.34-fold Up; FDR = 0.000403; PValue = 6.01e-05; mean CPM = 39.83; activating transcription factor 2" ID="ID_192626885" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_1736222953" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG1: 1.31-fold Down; FDR = 0.00352; PValue = 0.000707; mean CPM = 53.66; phospholipase C, gamma 1" ID="ID_1565227920" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1995071759" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_710422280" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_1168265013" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_498665557" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AGTR1: 1.98-fold Up; FDR = 0.174; PValue = 0.0692; mean CPM = 1.101; angiotensin II receptor, type 1" ID="ID_655250154" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_365288623" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_725429753" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRKL: 1.11-fold Up; FDR = 0.371; PValue = 0.176; mean CPM = 34.10; v-crk sarcoma virus CT10 oncogene homolog (avian)-like" ID="ID_1769510252" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_977453798" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1007175885" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAQ: 1.05-fold Down; FDR = 0.889; PValue = 0.611; mean CPM = 9.623; Guanine nucleotide-binding protein G(Q) subunit alpha; Uncharacterized protein" ID="ID_507413157" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK1: 1.03-fold Down; FDR = 0.911; PValue = 0.705; mean CPM = 18.65; p21 protein (Cdc42/Rac)-activated kinase 1" ID="ID_748704750" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_1954777115" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_369421594" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_945610464" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAQ: No Change; FDR = 1; PValue = 0.975; mean CPM = 15.20; guanine nucleotide binding protein (G protein), q polypeptide" ID="ID_44524303" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AGT: 1.02-fold Down; FDR = 1; PValue = 0.996; mean CPM = 0.8004; angiotensinogen (serpin peptidase inhibitor, clade A, member 8)" ID="ID_1512607475" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/biocarta induction of apoptosis through dr3 and dr4/5 death receptors: Upregulated, FDR = 0.462, PValue = 0.0477" ID="ID_838376141" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_184777765" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF10: 44.5-fold Up; FDR = 2.83e-16; PValue = 2.4e-18; mean CPM = 6.029; Tumor necrosis factor ligand superfamily member 10 isoform 1; Uncharacterized protein" ID="ID_787959994" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BID: 1.66-fold Up; FDR = 5.41e-09; PValue = 2.19e-10; mean CPM = 35.19; BH3 interacting domain death agonist" ID="ID_926874831" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_978883940" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_1435600506" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LMNA: 1.49-fold Down; FDR = 4.66e-05; PValue = 5.23e-06; mean CPM = 1329; lamin A/C" ID="ID_802196338" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACTA1: 5.36-fold Down; FDR = 0.000251; PValue = 3.52e-05; mean CPM = 5.880; Uncharacterized protein" ID="ID_1597036934" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PARP1: 1.46-fold Down; FDR = 0.00173; PValue = 0.000315; mean CPM = 46.95; poly (ADP-ribose) polymerase 1" ID="ID_537567502" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K14: 1.47-fold Down; FDR = 0.00704; PValue = 0.00157; mean CPM = 9.470; mitogen-activated protein kinase kinase kinase 14" ID="ID_1553179654" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP10: 1.81-fold Up; FDR = 0.0175; PValue = 0.0045; mean CPM = 2.876; caspase 10, apoptosis-related cysteine peptidase" ID="ID_873428257" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRADD: 1.22-fold Up; FDR = 0.0319; PValue = 0.00907; mean CPM = 34.75; TNFRSF1A-associated via death domain" ID="ID_1353817045" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FADD: 1.18-fold Down; FDR = 0.0936; PValue = 0.0324; mean CPM = 30.89; Uncharacterized protein" ID="ID_1505702637" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP6: 1.17-fold Up; FDR = 0.197; PValue = 0.0807; mean CPM = 14.25; caspase 6, apoptosis-related cysteine peptidase" ID="ID_1368803212" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP7: 1.15-fold Up; FDR = 0.218; PValue = 0.0916; mean CPM = 21.49; caspase 7, apoptosis-related cysteine peptidase" ID="ID_730037501" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_777720946" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF25: 1.2-fold Up; FDR = 0.772; PValue = 0.471; mean CPM = 1.687; tumor necrosis factor receptor superfamily, member 25" ID="ID_1212142210" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GAS2: 1.4-fold Up; FDR = 0.826; PValue = 0.526; mean CPM = 0.7983; growth arrest-specific 2" ID="ID_1521862572" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPTAN1: 1.01-fold Up; FDR = 1; PValue = 0.881; mean CPM = 946.2; spectrin, alpha, non-erythrocytic 1" ID="ID_671712239" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/biocarta tnf/stress related signaling: Upregulated, FDR = 0.462, PValue = 0.0499" ID="ID_1615994654" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TANK: 1.77-fold Up; FDR = 3.82e-13; PValue = 5.66e-15; mean CPM = 62.24; TRAF family member-associated NFKB activator" ID="ID_1038950365" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_1043291970" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1606381022" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF1: 1.51-fold Up; FDR = 5.28e-06; PValue = 4.58e-07; mean CPM = 22.13; activating transcription factor 1" ID="ID_580515931" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP4K4: 1.4-fold Down; FDR = 3.08e-05; PValue = 3.27e-06; mean CPM = 242.8; mitogen-activated protein kinase kinase kinase kinase 4" ID="ID_1826531605" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_1950934850" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP4K2: 1.36-fold Down; FDR = 0.000898; PValue = 0.000149; mean CPM = 21.71; mitogen-activated protein kinase kinase kinase kinase 2" ID="ID_585626618" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAG4: 1.32-fold Up; FDR = 0.00191; PValue = 0.000353; mean CPM = 25.62; BCL2-associated athanogene 4" ID="ID_1950909998" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRADD: 1.22-fold Up; FDR = 0.0319; PValue = 0.00907; mean CPM = 34.75; TNFRSF1A-associated via death domain" ID="ID_319247706" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_259506406" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1379304905" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1A: 1.11-fold Up; FDR = 0.297; PValue = 0.134; mean CPM = 134.7; tumor necrosis factor receptor superfamily, member 1A" ID="ID_157463961" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1061407204" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRADD: 1.1-fold Down; FDR = 0.827; PValue = 0.527; mean CPM = 3.992; CASP2 and RIPK1 domain containing adaptor with death domain" ID="ID_1352460812" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1301667787" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_1772817552" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP2: 1.05-fold Up; FDR = 0.906; PValue = 0.667; mean CPM = 12.88; caspase 2, apoptosis-related cysteine peptidase" ID="ID_1693265256" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- </node>
- <node TEXT="kegg gene set collection" ID="ID_1630707901" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="graphite/kegg RIG-I-like receptor signaling pathway: Upregulated, FDR = 0.082, PValue = 0.000863" ID="ID_700229955" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="IFIH1: 14.7-fold Up; FDR = 8.74e-23; PValue = 1.68e-25; mean CPM = 49.84; interferon induced with helicase C domain 1" ID="ID_1904026005" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DHX58: 3.84-fold Up; FDR = 1.33e-19; PValue = 5.45e-22; mean CPM = 98.66; DEXH (Asp-Glu-X-His) box polypeptide 58" ID="ID_884437158" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRIM25: 3.78-fold Up; FDR = 3.13e-19; PValue = 1.41e-21; mean CPM = 121.6; tripartite motif-containing 25" ID="ID_1639740762" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DDX58: 6.4-fold Up; FDR = 5.12e-18; PValue = 3.06e-20; mean CPM = 86.14; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58" ID="ID_820964373" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF7: 14.8-fold Up; FDR = 7.66e-18; PValue = 4.82e-20; mean CPM = 11.54; Macaca mulatta interferon regulatory factor 7 (IRF7), mRNA." ID="ID_1983558386" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_1467633183" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ISG15: 15.5-fold Up; FDR = 2.16e-15; PValue = 2.02e-17; mean CPM = 55.60; ISG15 ubiquitin-like modifier" ID="ID_456004965" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TANK: 1.77-fold Up; FDR = 3.82e-13; PValue = 5.66e-15; mean CPM = 62.24; TRAF family member-associated NFKB activator" ID="ID_1680599242" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAVS: 1.92-fold Down; FDR = 2.7e-09; PValue = 1.02e-10; mean CPM = 29.16; mitochondrial antiviral signaling protein" ID="ID_555792275" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_486888165" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_750237929" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATG12: 1.67-fold Up; FDR = 8.54e-07; PValue = 6.03e-08; mean CPM = 48.65; ATG12 autophagy related 12 homolog (S. cerevisiae)" ID="ID_1866328241" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLRX1: 1.49-fold Down; FDR = 9.67e-07; PValue = 6.97e-08; mean CPM = 54.52; NLR family member X1" ID="ID_1143366525" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYLD: 1.46-fold Up; FDR = 1.36e-06; PValue = 1.01e-07; mean CPM = 77.47; cylindromatosis (turban tumor syndrome)" ID="ID_1771201162" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_120306824" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBKBP1: 3.3-fold Up; FDR = 6.66e-06; PValue = 5.98e-07; mean CPM = 7.002; TBK1 binding protein 1" ID="ID_681168929" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATG5: 1.37-fold Up; FDR = 0.000194; PValue = 2.63e-05; mean CPM = 36.05; ATG5 autophagy related 5 homolog (S. cerevisiae)" ID="ID_980269551" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_619661370" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBK1: 1.3-fold Up; FDR = 0.00337; PValue = 0.000674; mean CPM = 30.46; TANK-binding kinase 1" ID="ID_1923060255" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1473663705" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_1215096595" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMEM173: 1.25-fold Up; FDR = 0.00837; PValue = 0.00192; mean CPM = 219.1; transmembrane protein 173" ID="ID_1445856997" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP10: 1.81-fold Up; FDR = 0.0175; PValue = 0.0045; mean CPM = 2.876; caspase 10, apoptosis-related cysteine peptidase" ID="ID_178442775" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRADD: 1.22-fold Up; FDR = 0.0319; PValue = 0.00907; mean CPM = 34.75; TNFRSF1A-associated via death domain" ID="ID_786353288" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SIKE1: 1.21-fold Up; FDR = 0.0353; PValue = 0.0102; mean CPM = 31.55; suppressor of IKBKE 1" ID="ID_955333473" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1857338004" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="OTUD5: 1.16-fold Down; FDR = 0.0921; PValue = 0.0318; mean CPM = 54.00; OTU domain containing 5" ID="ID_1275713355" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FADD: 1.18-fold Down; FDR = 0.0936; PValue = 0.0324; mean CPM = 30.89; Uncharacterized protein" ID="ID_1493426024" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_1863336593" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_50396381" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_1098248081" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_936123140" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK12: 1.19-fold Down; FDR = 0.422; PValue = 0.208; mean CPM = 6.569; mitogen-activated protein kinase 12" ID="ID_933826618" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DDX3X: 1.09-fold Up; FDR = 0.478; PValue = 0.244; mean CPM = 344.2; DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked" ID="ID_1400888946" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK13: 1.22-fold Down; FDR = 0.536; PValue = 0.284; mean CPM = 3.100; mitogen-activated protein kinase 13" ID="ID_1821415" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF3: 1.07-fold Up; FDR = 0.611; PValue = 0.338; mean CPM = 34.56; TNF receptor-associated factor 3" ID="ID_839453979" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIN1: 1.04-fold Down; FDR = 0.845; PValue = 0.554; mean CPM = 85.07; peptidylprolyl cis/trans isomerase, NIMA-interacting 1" ID="ID_1860140044" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RNF125: 1.54-fold Down; FDR = 0.854; PValue = 0.565; mean CPM = 0.8270; ring finger protein 125" ID="ID_1268426707" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_896103228" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKE: 1.03-fold Up; FDR = 0.929; PValue = 0.737; mean CPM = 21.61; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon" ID="ID_978927261" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_144484263" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DAK: 1.01-fold Up; FDR = 1; PValue = 0.859; mean CPM = 25.02; dihydroxyacetone kinase 2 homolog (S. cerevisiae)" ID="ID_162116388" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_582465240" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AZI2: No Change; FDR = 1; PValue = 0.985; mean CPM = 39.18; Uncharacterized protein" ID="ID_1694875346" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg NOD-like receptor signaling pathway: Upregulated, FDR = 0.082, PValue = 0.00139" ID="ID_708560917" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CASP5: 68-fold Up; FDR = 3.54e-19; PValue = 1.64e-21; mean CPM = 7.240; caspase 5, apoptosis-related cysteine peptidase" ID="ID_318886169" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_986156904" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK2: 3.75-fold Up; FDR = 6.1e-16; PValue = 5.38e-18; mean CPM = 68.21; receptor-interacting serine-threonine kinase 2" ID="ID_1244790426" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CARD6: 2.33-fold Up; FDR = 1.15e-12; PValue = 1.89e-14; mean CPM = 30.09; caspase recruitment domain family, member 6" ID="ID_1421855979" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CARD8: 2.48-fold Up; FDR = 2.44e-11; PValue = 5.59e-13; mean CPM = 14.84; caspase recruitment domain family, member 8" ID="ID_417712909" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC2: 1.96-fold Up; FDR = 1.01e-10; PValue = 2.62e-12; mean CPM = 53.58; baculoviral IAP repeat-containing 2" ID="ID_717151695" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CARD8: 2.02-fold Up; FDR = 1.41e-09; PValue = 4.93e-11; mean CPM = 15.89; caspase recruitment domain family, member 8" ID="ID_1776164599" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1693234226" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLRC4: 6.6-fold Up; FDR = 8.52e-08; PValue = 4.67e-09; mean CPM = 3.347; NLR family, CARD domain containing 4" ID="ID_993984945" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC3: 2.79-fold Up; FDR = 1.74e-06; PValue = 1.32e-07; mean CPM = 95.34; baculoviral IAP repeat-containing 3" ID="ID_3009734" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1014255782" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFAIP3: 1.79-fold Up; FDR = 3.14e-05; PValue = 3.34e-06; mean CPM = 52.47; tumor necrosis factor, alpha-induced protein 3" ID="ID_914807779" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90AA1: 1.41-fold Up; FDR = 4.17e-05; PValue = 4.62e-06; mean CPM = 609.6; heat shock protein 90kDa alpha (cytosolic), class A member 2" ID="ID_1717010389" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CARD9: 1.53-fold Up; FDR = 9.57e-05; PValue = 1.18e-05; mean CPM = 16.72; caspase recruitment domain family, member 9" ID="ID_274727925" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP2: 1.45-fold Up; FDR = 0.000179; PValue = 2.4e-05; mean CPM = 65.31; TGF-beta activated kinase 1/MAP3K7 binding protein 2" ID="ID_316035862" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOD1: 1.63-fold Up; FDR = 0.000193; PValue = 2.61e-05; mean CPM = 58.36; nucleotide-binding oligomerization domain containing 1" ID="ID_1823044155" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SUGT1: 1.35-fold Up; FDR = 0.000193; PValue = 2.61e-05; mean CPM = 54.75; SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)" ID="ID_1431991214" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP3: 1.5-fold Up; FDR = 0.000276; PValue = 3.92e-05; mean CPM = 11.67; TGF-beta activated kinase 1/MAP3K7 binding protein 3" ID="ID_1184864786" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1496127213" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90B1: 1.28-fold Down; FDR = 0.00538; PValue = 0.00115; mean CPM = 1017; heat shock protein 90kDa beta (Grp94), member 1" ID="ID_763083517" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_1903177225" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1140586639" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_542249579" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_436632309" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_1835035873" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PYCARD: 1.38-fold Down; FDR = 0.241; PValue = 0.103; mean CPM = 3.110; PYD and CARD domain containing" ID="ID_1441341505" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLRP3: 1.84-fold Down; FDR = 0.32; PValue = 0.147; mean CPM = 0.9630; NLR family, pyrin domain containing 3" ID="ID_206522691" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP1: 1.12-fold Down; FDR = 0.351; PValue = 0.165; mean CPM = 17.96; TGF-beta activated kinase 1/MAP3K7 binding protein 1" ID="ID_239860011" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_777156084" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1524379067" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK12: 1.19-fold Down; FDR = 0.422; PValue = 0.208; mean CPM = 6.569; mitogen-activated protein kinase 12" ID="ID_1100502745" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1026441006" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK13: 1.22-fold Down; FDR = 0.536; PValue = 0.284; mean CPM = 3.100; mitogen-activated protein kinase 13" ID="ID_1498860386" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90AB1: 1.07-fold Down; FDR = 0.652; PValue = 0.369; mean CPM = 905.8; heat shock protein 90kDa alpha (cytosolic), class B member 1" ID="ID_1227867154" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90AA1: 1.8-fold Up; FDR = 0.749; PValue = 0.449; mean CPM = 0.8328; heat shock protein 90kDa alpha (cytosolic), class A member 1" ID="ID_981744151" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MEFV: 1.13-fold Up; FDR = 0.813; PValue = 0.51; mean CPM = 6.740; Mediterranean fever" ID="ID_1372312831" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_929682733" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOD2: 1.17-fold Up; FDR = 0.866; PValue = 0.583; mean CPM = 1.911; nucleotide-binding oligomerization domain containing 2" ID="ID_1538210087" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_1324319976" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRIP6: 1.01-fold Down; FDR = 1; PValue = 0.92; mean CPM = 125.6; thyroid hormone receptor interactor 6" ID="ID_1542327509" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSTPIP1: 1.03-fold Down; FDR = 1; PValue = 0.929; mean CPM = 1.615; proline-serine-threonine phosphatase interacting protein 1" ID="ID_1084846175" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_1311174166" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Herpes simplex infection: Upregulated, FDR = 0.082, PValue = 0.00173" ID="ID_1507111057" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TLR2: 8.94-fold Up; FDR = 6.97e-23; PValue = 1.25e-25; mean CPM = 18.41; toll-like receptor 2" ID="ID_491879253" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFIH1: 14.7-fold Up; FDR = 8.74e-23; PValue = 1.68e-25; mean CPM = 49.84; interferon induced with helicase C domain 1" ID="ID_575687855" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR3: 10.3-fold Up; FDR = 1.95e-21; PValue = 5.6e-24; mean CPM = 35.70; toll-like receptor 3" ID="ID_477837861" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="OAS1: 41-fold Up; FDR = 1.01e-20; PValue = 3.28e-23; mean CPM = 37.38; Macaca mulatta 2',5'-oligoadenylate synthetase 1, 40/46kDa (OAS1), mRNA." ID="ID_1444021807" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF9: 3.85-fold Up; FDR = 2.6e-19; PValue = 1.12e-21; mean CPM = 106.4; interferon regulatory factor 9" ID="ID_545674652" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT2: 2.67-fold Up; FDR = 8.02e-19; PValue = 4.03e-21; mean CPM = 185.6; signal transducer and activator of transcription 2, 113kDa" ID="ID_1708733646" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_347004933" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1965444301" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000003602: 4.73-fold Up; FDR = 3.68e-18; PValue = 2.14e-20; mean CPM = 35.47; Uncharacterized protein" ID="ID_1654750635" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DDX58: 6.4-fold Up; FDR = 5.12e-18; PValue = 3.06e-20; mean CPM = 86.14; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58" ID="ID_713382662" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2AK2: 3.01-fold Up; FDR = 6.08e-18; PValue = 3.74e-20; mean CPM = 47.85; eukaryotic translation initiation factor 2-alpha kinase 2" ID="ID_360805114" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF7: 14.8-fold Up; FDR = 7.66e-18; PValue = 4.82e-20; mean CPM = 11.54; Macaca mulatta interferon regulatory factor 7 (IRF7), mRNA." ID="ID_65648375" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_749714760" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF14: 4.66-fold Up; FDR = 2.46e-16; PValue = 2.07e-18; mean CPM = 36.12; Macaca mulatta tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) (TNFRSF14), mRNA." ID="ID_1646567832" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="OAS2: 14.9-fold Up; FDR = 3.5e-15; PValue = 3.41e-17; mean CPM = 85.83; 2'-5'-oligoadenylate synthetase 2, 69/71kDa" ID="ID_140124093" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAVS: 1.92-fold Down; FDR = 2.7e-09; PValue = 1.02e-10; mean CPM = 29.16; mitochondrial antiviral signaling protein" ID="ID_1964404546" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RNASEL: 1.71-fold Up; FDR = 7.18e-09; PValue = 2.98e-10; mean CPM = 21.59; ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)" ID="ID_1296461033" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_214047693" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_1726060992" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR2: 1.74-fold Up; FDR = 1.85e-06; PValue = 1.44e-07; mean CPM = 26.05; interferon (alpha, beta and omega) receptor 2" ID="ID_64219498" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1219123148" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2AK3: 1.59-fold Down; FDR = 2.47e-06; PValue = 1.96e-07; mean CPM = 33.81; eukaryotic translation initiation factor 2-alpha kinase 3" ID="ID_112416154" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HCFC1: 1.45-fold Down; FDR = 1.15e-05; PValue = 1.1e-06; mean CPM = 107.1; host cell factor C1 (VP16-accessory protein)" ID="ID_782129807" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF1: 2.6-fold Down; FDR = 1.48e-05; PValue = 1.46e-06; mean CPM = 20.19; TNF receptor-associated factor 1" ID="ID_948431626" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2S1: 1.42-fold Up; FDR = 5.59e-05; PValue = 6.42e-06; mean CPM = 79.87; eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa" ID="ID_186617636" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP2: 1.45-fold Up; FDR = 0.000179; PValue = 2.4e-05; mean CPM = 65.31; TGF-beta activated kinase 1/MAP3K7 binding protein 2" ID="ID_980167662" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS3: 1.69-fold Up; FDR = 0.000994; PValue = 0.000167; mean CPM = 37.76; suppressor of cytokine signaling 3" ID="ID_1122838006" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C1QBP: 1.36-fold Up; FDR = 0.00107; PValue = 0.000183; mean CPM = 83.61; complement component 1, q subcomponent binding protein" ID="ID_1781399149" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR1: 1.31-fold Up; FDR = 0.00151; PValue = 0.000268; mean CPM = 37.77; interferon gamma receptor 1" ID="ID_529244060" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBK1: 1.3-fold Up; FDR = 0.00337; PValue = 0.000674; mean CPM = 30.46; TANK-binding kinase 1" ID="ID_126247023" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_911400504" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_1230090977" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR1: 1.27-fold Up; FDR = 0.0101; PValue = 0.00237; mean CPM = 82.39; Uncharacterized protein" ID="ID_1932700896" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SRPK1: 1.24-fold Up; FDR = 0.0118; PValue = 0.00283; mean CPM = 43.50; SRSF protein kinase 1" ID="ID_10696524" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSNK2A2: 1.28-fold Up; FDR = 0.0129; PValue = 0.00314; mean CPM = 19.86; casein kinase 2, alpha prime polypeptide" ID="ID_1701229990" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYK2: 1.24-fold Down; FDR = 0.0142; PValue = 0.00354; mean CPM = 42.58; tyrosine kinase 2" ID="ID_969598979" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SFRS6: 1.23-fold Down; FDR = 0.0161; PValue = 0.00409; mean CPM = 92.28; splicing factor, arginine/serine-rich 6" ID="ID_1635570064" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK2: 1.23-fold Down; FDR = 0.0194; PValue = 0.00507; mean CPM = 36.76; cyclin-dependent kinase 2" ID="ID_541267506" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR2: 1.23-fold Up; FDR = 0.0258; PValue = 0.00707; mean CPM = 46.52; interferon gamma receptor 2 (interferon gamma transducer 1)" ID="ID_1906399005" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_1395723096" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_360877024" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FADD: 1.18-fold Down; FDR = 0.0936; PValue = 0.0324; mean CPM = 30.89; Uncharacterized protein" ID="ID_1115935309" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_151018332" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_70060341" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_1732819922" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1099984848" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SFRS4: 1.15-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 47.62; splicing factor, arginine/serine-rich 4" ID="ID_650338687" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000039103: 1.67-fold Down; FDR = 0.221; PValue = 0.0927; mean CPM = 1.310; Uncharacterized protein" ID="ID_1668437172" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1A: 1.11-fold Up; FDR = 0.297; PValue = 0.134; mean CPM = 134.7; tumor necrosis factor receptor superfamily, member 1A" ID="ID_1107587384" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP1: 1.12-fold Down; FDR = 0.351; PValue = 0.165; mean CPM = 17.96; TGF-beta activated kinase 1/MAP3K7 binding protein 1" ID="ID_148166709" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TICAM1: 1.11-fold Down; FDR = 0.398; PValue = 0.192; mean CPM = 26.73; toll-like receptor adaptor molecule 1" ID="ID_1997010197" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SFRS5: 1.1-fold Up; FDR = 0.399; PValue = 0.193; mean CPM = 203.9; splicing factor, arginine/serine-rich 5" ID="ID_1439907008" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_667504743" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2AK1: 1.09-fold Up; FDR = 0.499; PValue = 0.258; mean CPM = 34.88; Uncharacterized protein" ID="ID_224883362" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP1CB: 1.08-fold Up; FDR = 0.566; PValue = 0.306; mean CPM = 108.6; protein phosphatase 1, catalytic subunit, beta isozyme" ID="ID_1895791585" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SRSF9: 1.07-fold Down; FDR = 0.595; PValue = 0.326; mean CPM = 49.60; Uncharacterized protein" ID="ID_507789392" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF3: 1.07-fold Up; FDR = 0.611; PValue = 0.338; mean CPM = 34.56; TNF receptor-associated factor 3" ID="ID_997236839" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2AK4: 1.06-fold Up; FDR = 0.681; PValue = 0.391; mean CPM = 104.8; eukaryotic translation initiation factor 2 alpha kinase 4" ID="ID_1773405482" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HCFC2: 1.07-fold Down; FDR = 0.701; PValue = 0.408; mean CPM = 22.13; host cell factor C2" ID="ID_1626026929" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNB1: 1.79-fold Up; FDR = 0.731; PValue = 0.433; mean CPM = 0.8526; interferon, beta 1, fibroblast" ID="ID_1768910400" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_1972780964" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA6: 1.41-fold Down; FDR = 0.807; PValue = 0.504; mean CPM = 0.8019; interferon, alpha 6" ID="ID_1434743999" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SRSF1: 1.05-fold Down; FDR = 0.812; PValue = 0.509; mean CPM = 151.1; Serine/arginine-rich splicing factor 1 isoform 1; Uncharacterized protein" ID="ID_178965187" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYCS: 1.05-fold Up; FDR = 0.854; PValue = 0.565; mean CPM = 93.43; cytochrome c, somatic" ID="ID_846296584" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1313743755" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000040219: 1.08-fold Up; FDR = 0.86; PValue = 0.575; mean CPM = 8.818; Uncharacterized protein" ID="ID_841166245" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_102225014" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_787948980" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SFRS3: 1.03-fold Up; FDR = 0.899; PValue = 0.631; mean CPM = 170.5; splicing factor, arginine/serine-rich 3" ID="ID_524398544" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF14: 1.16-fold Down; FDR = 0.903; PValue = 0.645; mean CPM = 0.7940; tumor necrosis factor (ligand) superfamily, member 14" ID="ID_332468021" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA13: 1.13-fold Up; FDR = 0.908; PValue = 0.677; mean CPM = 0.7960; interferon, alpha 13" ID="ID_480497658" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK1: 1.07-fold Up; FDR = 0.908; PValue = 0.682; mean CPM = 14.72; Uncharacterized protein" ID="ID_798985789" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA8: 1.13-fold Down; FDR = 0.911; PValue = 0.702; mean CPM = 0.7910; interferon, alpha 8" ID="ID_1195529988" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKE: 1.03-fold Up; FDR = 0.929; PValue = 0.737; mean CPM = 21.61; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon" ID="ID_576878863" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FASLG: 1.2-fold Down; FDR = 0.941; PValue = 0.757; mean CPM = 0.8088; Fas ligand (TNF superfamily, member 6)" ID="ID_1423129997" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSNK2B: 1.02-fold Down; FDR = 0.956; PValue = 0.787; mean CPM = 77.24; Casein kinase II subunit beta (CK II beta)(Phosvitin)(Protein G5a)" ID="ID_589282256" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000009289: 1.07-fold Up; FDR = 0.963; PValue = 0.798; mean CPM = 2.536; Uncharacterized protein" ID="ID_1259000645" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA14: 1.22-fold Up; FDR = 0.965; PValue = 0.802; mean CPM = 0.8654; interferon, alpha 14" ID="ID_1456987503" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_1917285391" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA4: 1.28-fold Down; FDR = 0.983; PValue = 0.829; mean CPM = 0.8584; interferon, alpha 4" ID="ID_684689008" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PILRA: 1.07-fold Up; FDR = 0.998; PValue = 0.854; mean CPM = 0.9415; paired immunoglobin-like type 2 receptor alpha" ID="ID_516445817" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR9: 1.01-fold Down; FDR = 1; PValue = 0.859; mean CPM = 21.45; Macaca mulatta toll-like receptor 9 (TLR9), mRNA." ID="ID_1618590578" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SFRS7: 1.01-fold Down; FDR = 1; PValue = 0.873; mean CPM = 94.47; splicing factor, arginine/serine-rich 7, 35kDa" ID="ID_1172218546" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="POU2F3: 1.09-fold Down; FDR = 1; PValue = 0.884; mean CPM = 0.8933; POU class 2 homeobox 3" ID="ID_1686176604" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_1795939590" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA1: No Change; FDR = 1; PValue = 0.998; mean CPM = 0.8014; interferon, alpha 1" ID="ID_1600386126" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Malaria: Upregulated, FDR = 0.082, PValue = 0.00193" ID="ID_799671102" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TLR2: 8.94-fold Up; FDR = 6.97e-23; PValue = 1.25e-25; mean CPM = 18.41; toll-like receptor 2" ID="ID_230320780" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICAM1: 24.6-fold Up; FDR = 2.39e-17; PValue = 1.64e-19; mean CPM = 232.4; intercellular adhesion molecule 1" ID="ID_1551610411" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MET: 2.57-fold Up; FDR = 3.56e-13; PValue = 5.22e-15; mean CPM = 242.4; Macaca mulatta met proto-oncogene (hepatocyte growth factor receptor) (MET), mRNA." ID="ID_1593573795" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR4: 3.45-fold Up; FDR = 3.1e-09; PValue = 1.19e-10; mean CPM = 7.456; Macaca mulatta toll-like receptor 4 (TLR4), mRNA." ID="ID_665364223" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HGF: 1.85-fold Down; FDR = 0.000377; PValue = 5.58e-05; mean CPM = 137.4; hepatocyte growth factor (hepapoietin A; scatter factor)" ID="ID_1326551641" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40: 2.76-fold Up; FDR = 0.00039; PValue = 5.79e-05; mean CPM = 9.139; CD40 molecule, TNF receptor superfamily member 5" ID="ID_1681039353" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB2: 1.55-fold Down; FDR = 0.0187; PValue = 0.00485; mean CPM = 34.87; Integrin beta" ID="ID_1242234601" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR9: 1.01-fold Down; FDR = 1; PValue = 0.859; mean CPM = 21.45; Macaca mulatta toll-like receptor 9 (TLR9), mRNA." ID="ID_577890380" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAL: 1.03-fold Up; FDR = 1; PValue = 0.95; mean CPM = 1.035; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)" ID="ID_469254972" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40LG: 1.01-fold Down; FDR = 1; PValue = 0.982; mean CPM = 0.8653; CD40 ligand" ID="ID_1171776754" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg ECM-receptor interaction: Downregulated, FDR = 0.101, PValue = 0.00298" ID="ID_1737594888" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="COL4A1: 7.03-fold Down; FDR = 1.47e-15; PValue = 1.34e-17; mean CPM = 3419; collagen, type IV, alpha 1" ID="ID_711010996" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL5A1: 4.69-fold Down; FDR = 3.09e-15; PValue = 2.99e-17; mean CPM = 1718; collagen, type V, alpha 1" ID="ID_1236977070" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL3A1: 20.5-fold Down; FDR = 5.71e-15; PValue = 5.82e-17; mean CPM = 5961; collagen, type III, alpha 1" ID="ID_936552764" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD47: 2.13-fold Up; FDR = 6.33e-15; PValue = 6.54e-17; mean CPM = 59.15; CD47 molecule" ID="ID_695930630" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL11A1: 12.2-fold Down; FDR = 8.67e-15; PValue = 9.24e-17; mean CPM = 318.0; collagen, type XI, alpha 1" ID="ID_1426404294" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA5: 3.79-fold Down; FDR = 1.33e-14; PValue = 1.48e-16; mean CPM = 1237; integrin, alpha 5 (fibronectin receptor, alpha polypeptide)" ID="ID_535178287" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL6A3: 4.93-fold Down; FDR = 5.63e-14; PValue = 6.87e-16; mean CPM = 1415; collagen, type VI, alpha 3" ID="ID_992824706" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL1A1: 21.5-fold Down; FDR = 1.13e-13; PValue = 1.5e-15; mean CPM = 15389; collagen, type I, alpha 1" ID="ID_238398170" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL1A2: 10.7-fold Down; FDR = 3.82e-13; PValue = 5.68e-15; mean CPM = 17923; collagen, type I, alpha 2" ID="ID_170919549" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMC1: 2.28-fold Down; FDR = 6.46e-13; PValue = 1.01e-14; mean CPM = 812.1; laminin, gamma 1 (formerly LAMB2)" ID="ID_182582115" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016591: 4.2-fold Down; FDR = 1.3e-11; PValue = 2.78e-13; mean CPM = 34.90; Uncharacterized protein" ID="ID_795381096" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016587: 4.92-fold Down; FDR = 1.6e-11; PValue = 3.5e-13; mean CPM = 51.70; Uncharacterized protein" ID="ID_1460273504" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAV: 2.64-fold Down; FDR = 6.04e-11; PValue = 1.51e-12; mean CPM = 337.3; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)" ID="ID_447269702" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL5A3: 5.21-fold Down; FDR = 1.78e-10; PValue = 4.98e-12; mean CPM = 79.70; collagen, type V, alpha 3" ID="ID_828437078" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THBS2: 6.46-fold Down; FDR = 3.61e-10; PValue = 1.1e-11; mean CPM = 199.9; thrombospondin 2" ID="ID_541331368" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB8: 3.97-fold Up; FDR = 6.37e-10; PValue = 2.06e-11; mean CPM = 11.37; integrin, beta 8" ID="ID_1005563494" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA2: 2.84-fold Up; FDR = 7.38e-10; PValue = 2.42e-11; mean CPM = 176.3; integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)" ID="ID_1322249904" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPG2: 2.83-fold Down; FDR = 8.45e-10; PValue = 2.83e-11; mean CPM = 1670; heparan sulfate proteoglycan 2" ID="ID_1418122464" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB3: 5.02-fold Down; FDR = 1.72e-09; PValue = 6.17e-11; mean CPM = 43.21; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)" ID="ID_939630030" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL5A2: 2.25-fold Down; FDR = 2.26e-09; PValue = 8.27e-11; mean CPM = 2999; collagen, type V, alpha 2" ID="ID_565520867" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB5: 1.61-fold Down; FDR = 8.23e-09; PValue = 3.47e-10; mean CPM = 471.0; integrin, beta 5" ID="ID_303972527" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA10: 4.95-fold Down; FDR = 1.77e-08; PValue = 8.13e-10; mean CPM = 5.184; integrin, alpha 10" ID="ID_257767972" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA8: 4.04-fold Down; FDR = 5.89e-08; PValue = 3.12e-09; mean CPM = 145.8; integrin, alpha 8" ID="ID_1367465356" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THBS3: 1.97-fold Up; FDR = 7.19e-08; PValue = 3.88e-09; mean CPM = 128.6; thrombospondin 3" ID="ID_163155783" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COMP: 4.64-fold Down; FDR = 7.47e-08; PValue = 4.04e-09; mean CPM = 13.27; cartilage oligomeric matrix protein" ID="ID_1240104589" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SDC4: 1.79-fold Up; FDR = 1.95e-07; PValue = 1.16e-08; mean CPM = 109.0; syndecan 4" ID="ID_1385136434" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNC: 1.97-fold Down; FDR = 4.07e-07; PValue = 2.63e-08; mean CPM = 2667; tenascin C" ID="ID_107808187" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THBS1: 2.74-fold Down; FDR = 1.68e-06; PValue = 1.28e-07; mean CPM = 25785; thrombospondin 1" ID="ID_1314015214" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL4A5: 2.03-fold Down; FDR = 3.06e-06; PValue = 2.48e-07; mean CPM = 9.810; collagen, type IV, alpha 5" ID="ID_1626165614" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SV2A: 5.8-fold Down; FDR = 3.38e-06; PValue = 2.79e-07; mean CPM = 1.583; synaptic vesicle glycoprotein 2A" ID="ID_897985997" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL6A1: 1.85-fold Down; FDR = 6.65e-06; PValue = 5.96e-07; mean CPM = 1937; collagen, type VI, alpha 1" ID="ID_201828591" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMC2: 2.28-fold Down; FDR = 9.83e-06; PValue = 9.24e-07; mean CPM = 16.99; laminin, gamma 2" ID="ID_694397614" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SDC1: 2.19-fold Down; FDR = 2.55e-05; PValue = 2.66e-06; mean CPM = 12.60; syndecan 1" ID="ID_1815243646" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPP1: 2.25-fold Down; FDR = 7.74e-05; PValue = 9.29e-06; mean CPM = 35.33; secreted phosphoprotein 1" ID="ID_536612678" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL6A2: 1.47-fold Down; FDR = 0.000287; PValue = 4.1e-05; mean CPM = 1544; collagen, type VI, alpha 2" ID="ID_1023102901" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB2: 1.48-fold Down; FDR = 0.000398; PValue = 5.93e-05; mean CPM = 695.6; laminin, beta 2 (laminin S)" ID="ID_315802255" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA3: 1.34-fold Down; FDR = 0.000518; PValue = 7.96e-05; mean CPM = 126.8; integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)" ID="ID_572919225" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB4: 1.66-fold Down; FDR = 0.00369; PValue = 0.000748; mean CPM = 5.291; integrin, beta 4" ID="ID_590066567" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GP1BA: 2.34-fold Down; FDR = 0.0114; PValue = 0.00273; mean CPM = 1.873; glycoprotein Ib (platelet), alpha polypeptide" ID="ID_685522027" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FN1: 1.7-fold Down; FDR = 0.0164; PValue = 0.00417; mean CPM = 40317; fibronectin 1" ID="ID_593989274" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA2B: 1.71-fold Down; FDR = 0.0187; PValue = 0.00486; mean CPM = 2.655; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)" ID="ID_735633494" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL2A1: 2.38-fold Down; FDR = 0.0368; PValue = 0.0107; mean CPM = 1.117; Uncharacterized protein" ID="ID_1977206828" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DAG1: 1.54-fold Down; FDR = 0.0661; PValue = 0.0214; mean CPM = 3.013; dystroglycan 1 (dystrophin-associated glycoprotein 1)" ID="ID_1060197052" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB1: 1.23-fold Up; FDR = 0.0759; PValue = 0.0253; mean CPM = 2700; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)" ID="ID_832187594" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMA4: 1.2-fold Down; FDR = 0.0793; PValue = 0.0266; mean CPM = 624.4; laminin, alpha 4" ID="ID_805873617" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IBSP: 2.51-fold Down; FDR = 0.128; PValue = 0.0476; mean CPM = 0.8896; integrin-binding sialoprotein" ID="ID_183053259" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VWF: 1.42-fold Down; FDR = 0.174; PValue = 0.069; mean CPM = 24.05; von Willebrand factor" ID="ID_416857272" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB4: 1.81-fold Down; FDR = 0.237; PValue = 0.101; mean CPM = 1.043; laminin, beta 4" ID="ID_1035633183" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HMMR: 1.35-fold Down; FDR = 0.262; PValue = 0.114; mean CPM = 14.06; Uncharacterized protein" ID="ID_228262036" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014969: 1.93-fold Down; FDR = 0.303; PValue = 0.137; mean CPM = 0.9384; Uncharacterized protein" ID="ID_686788948" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB3: 1.6-fold Down; FDR = 0.303; PValue = 0.137; mean CPM = 1.445; laminin, beta 3" ID="ID_661882764" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL6A6: 1.78-fold Down; FDR = 0.354; PValue = 0.166; mean CPM = 0.9461; collagen, type VI, alpha 6" ID="ID_420024786" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL4A3: 1.67-fold Down; FDR = 0.422; PValue = 0.207; mean CPM = 0.9315; collagen, type IV, alpha 3 (Goodpasture antigen)" ID="ID_278915905" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNN: 1.32-fold Up; FDR = 0.425; PValue = 0.209; mean CPM = 2.061; tenascin N" ID="ID_1183692692" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000026812: 1.61-fold Down; FDR = 0.46; PValue = 0.232; mean CPM = 0.9948; Uncharacterized protein" ID="ID_816583138" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THBS4: 1.64-fold Down; FDR = 0.498; PValue = 0.257; mean CPM = 0.9543; thrombospondin 4" ID="ID_1892734371" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA1: 1.1-fold Down; FDR = 0.57; PValue = 0.308; mean CPM = 422.3; integrin, alpha 1" ID="ID_1816433567" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GP5: 1.22-fold Up; FDR = 0.577; PValue = 0.313; mean CPM = 2.454; glycoprotein V (platelet)" ID="ID_1631344340" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA9: 1.3-fold Down; FDR = 0.595; PValue = 0.326; mean CPM = 1.685; integrin, alpha 9" ID="ID_1850656216" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL4A6: 1.4-fold Down; FDR = 0.631; PValue = 0.353; mean CPM = 1.078; collagen, type IV, alpha 6" ID="ID_1853688142" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VTN: 1.19-fold Up; FDR = 0.669; PValue = 0.382; mean CPM = 2.950; vitronectin" ID="ID_1643863070" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014966: 1.43-fold Down; FDR = 0.72; PValue = 0.423; mean CPM = 0.9009; Uncharacterized protein" ID="ID_1928267422" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA4: 1.16-fold Down; FDR = 0.722; PValue = 0.425; mean CPM = 5.425; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)" ID="ID_166344853" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB6: 1.4-fold Down; FDR = 0.732; PValue = 0.434; mean CPM = 0.9377; Integrin beta" ID="ID_1696791324" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GP9: 1.69-fold Up; FDR = 0.754; PValue = 0.454; mean CPM = 0.8166; glycoprotein IX (platelet)" ID="ID_1495586824" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SV2B: 1.71-fold Up; FDR = 0.794; PValue = 0.49; mean CPM = 0.8302; synaptic vesicle glycoprotein 2B" ID="ID_1619033503" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AGRN: 1.07-fold Down; FDR = 0.828; PValue = 0.53; mean CPM = 103.0; agrin" ID="ID_1118005646" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD36: 1.23-fold Up; FDR = 0.84; PValue = 0.547; mean CPM = 1.074; CD36 molecule (thrombospondin receptor)" ID="ID_858198933" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GP6: 1.29-fold Up; FDR = 0.845; PValue = 0.554; mean CPM = 0.9339; glycoprotein VI (platelet)" ID="ID_727055942" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL11A2: 1.03-fold Down; FDR = 1; PValue = 0.872; mean CPM = 2.131; collagen, type XI, alpha 2" ID="ID_57650600" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL24A1: 1.04-fold Up; FDR = 1; PValue = 0.898; mean CPM = 1.201; collagen, type XXIV, alpha 1" ID="ID_129792852" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNXB: 1.03-fold Up; FDR = 1; PValue = 0.909; mean CPM = 1.078; tenascin XB" ID="ID_212166227" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB7: 1.01-fold Down; FDR = 1; PValue = 0.968; mean CPM = 2.025; integrin, beta 7" ID="ID_1653767885" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD44: No Change; FDR = 1; PValue = 0.981; mean CPM = 487.7; CD44 molecule (Indian blood group)" ID="ID_992697806" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNR: 1.08-fold Down; FDR = 1; PValue = 0.984; mean CPM = 0.8556; tenascin R (restrictin, janusin)" ID="ID_1436016663" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Influenza A: Upregulated, FDR = 0.103, PValue = 0.00426" ID="ID_1010384369" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="IFIH1: 14.7-fold Up; FDR = 8.74e-23; PValue = 1.68e-25; mean CPM = 49.84; interferon induced with helicase C domain 1" ID="ID_1964426403" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR3: 10.3-fold Up; FDR = 1.95e-21; PValue = 5.6e-24; mean CPM = 35.70; toll-like receptor 3" ID="ID_1830945970" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="OAS1: 41-fold Up; FDR = 1.01e-20; PValue = 3.28e-23; mean CPM = 37.38; Macaca mulatta 2',5'-oligoadenylate synthetase 1, 40/46kDa (OAS1), mRNA." ID="ID_1801950139" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF9: 3.85-fold Up; FDR = 2.6e-19; PValue = 1.12e-21; mean CPM = 106.4; interferon regulatory factor 9" ID="ID_147076387" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRIM25: 3.78-fold Up; FDR = 3.13e-19; PValue = 1.41e-21; mean CPM = 121.6; tripartite motif-containing 25" ID="ID_876334738" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT2: 2.67-fold Up; FDR = 8.02e-19; PValue = 4.03e-21; mean CPM = 185.6; signal transducer and activator of transcription 2, 113kDa" ID="ID_421905627" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_1960287637" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_118263520" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000003602: 4.73-fold Up; FDR = 3.68e-18; PValue = 2.14e-20; mean CPM = 35.47; Uncharacterized protein" ID="ID_1032883519" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DDX58: 6.4-fold Up; FDR = 5.12e-18; PValue = 3.06e-20; mean CPM = 86.14; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58" ID="ID_1451013058" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2AK2: 3.01-fold Up; FDR = 6.08e-18; PValue = 3.74e-20; mean CPM = 47.85; eukaryotic translation initiation factor 2-alpha kinase 2" ID="ID_781426617" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF7: 14.8-fold Up; FDR = 7.66e-18; PValue = 4.82e-20; mean CPM = 11.54; Macaca mulatta interferon regulatory factor 7 (IRF7), mRNA." ID="ID_1604316903" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RSAD2: 37.4-fold Up; FDR = 7.72e-18; PValue = 4.9e-20; mean CPM = 9.742; radical S-adenosyl methionine domain containing 2" ID="ID_1779597281" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CIITA: 45.8-fold Up; FDR = 1.14e-17; PValue = 7.44e-20; mean CPM = 27.80; class II, major histocompatibility complex, transactivator" ID="ID_960723492" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF10: 44.5-fold Up; FDR = 2.83e-16; PValue = 2.4e-18; mean CPM = 6.029; Tumor necrosis factor ligand superfamily member 10 isoform 1; Uncharacterized protein" ID="ID_83901005" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="OAS2: 14.9-fold Up; FDR = 3.5e-15; PValue = 3.41e-17; mean CPM = 85.83; 2'-5'-oligoadenylate synthetase 2, 69/71kDa" ID="ID_708864080" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA2: 4.21-fold Down; FDR = 2.4e-14; PValue = 2.77e-16; mean CPM = 66.42; heat shock 70kDa protein 2" ID="ID_156557460" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL33: 5.25-fold Up; FDR = 5.38e-12; PValue = 1.05e-13; mean CPM = 531.4; interleukin 33" ID="ID_506099450" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAVS: 1.92-fold Down; FDR = 2.7e-09; PValue = 1.02e-10; mean CPM = 29.16; mitochondrial antiviral signaling protein" ID="ID_537276629" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR4: 3.45-fold Up; FDR = 3.1e-09; PValue = 1.19e-10; mean CPM = 7.456; Macaca mulatta toll-like receptor 4 (TLR4), mRNA." ID="ID_699292551" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA1B: 2.24-fold Down; FDR = 4.33e-09; PValue = 1.71e-10; mean CPM = 44.90; Heat shock 70 kDa protein 1A/1B (Heat shock 70 kDa protein 1/2)(HSP70.1/HSP70.2)(HSP70-1/HSP70-2)" ID="ID_1925049821" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RNASEL: 1.71-fold Up; FDR = 7.18e-09; PValue = 2.98e-10; mean CPM = 21.59; ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)" ID="ID_1339586331" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA8: 1.64-fold Up; FDR = 1.46e-08; PValue = 6.6e-10; mean CPM = 1881; heat shock 70kDa protein 8" ID="ID_1374887387" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK4: 1.8-fold Up; FDR = 3.31e-08; PValue = 1.64e-09; mean CPM = 12.89; interleukin-1 receptor-associated kinase 4" ID="ID_195162083" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_449193462" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1824701391" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_437896712" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_932551151" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NXF1: 1.53-fold Down; FDR = 1.55e-06; PValue = 1.16e-07; mean CPM = 49.36; nuclear RNA export factor 1" ID="ID_1982983242" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR2: 1.74-fold Up; FDR = 1.85e-06; PValue = 1.44e-07; mean CPM = 26.05; interferon (alpha, beta and omega) receptor 2" ID="ID_1666745626" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1524590257" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2AK3: 1.59-fold Down; FDR = 2.47e-06; PValue = 1.96e-07; mean CPM = 33.81; eukaryotic translation initiation factor 2-alpha kinase 3" ID="ID_690491632" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K3: 1.45-fold Down; FDR = 7.01e-06; PValue = 6.34e-07; mean CPM = 180.1; mitogen-activated protein kinase kinase 3" ID="ID_1546282182" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1158436852" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2S1: 1.42-fold Up; FDR = 5.59e-05; PValue = 6.42e-06; mean CPM = 79.87; eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa" ID="ID_403273950" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF10D: 1.84-fold Down; FDR = 5.9e-05; PValue = 6.84e-06; mean CPM = 32.06; tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain" ID="ID_169926041" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF2: 1.34-fold Up; FDR = 0.000403; PValue = 6.01e-05; mean CPM = 39.83; activating transcription factor 2" ID="ID_732699963" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NXT2: 2.01-fold Up; FDR = 0.000588; PValue = 9.2e-05; mean CPM = 5.026; nuclear transport factor 2-like export factor 2" ID="ID_487142863" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS3: 1.69-fold Up; FDR = 0.000994; PValue = 0.000167; mean CPM = 37.76; suppressor of cytokine signaling 3" ID="ID_59893654" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR1: 1.31-fold Up; FDR = 0.00151; PValue = 0.000268; mean CPM = 37.77; interferon gamma receptor 1" ID="ID_618882954" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBK1: 1.3-fold Up; FDR = 0.00337; PValue = 0.000674; mean CPM = 30.46; TANK-binding kinase 1" ID="ID_1971847614" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_80317071" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_884736795" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL18: 1.5-fold Down; FDR = 0.00981; PValue = 0.0023; mean CPM = 6.489; interleukin 18 (interferon-gamma-inducing factor)" ID="ID_1704168190" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR1: 1.27-fold Up; FDR = 0.0101; PValue = 0.00237; mean CPM = 82.39; Uncharacterized protein" ID="ID_1405892212" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYK2: 1.24-fold Down; FDR = 0.0142; PValue = 0.00354; mean CPM = 42.58; tyrosine kinase 2" ID="ID_1544668208" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1156833271" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA6: 2.05-fold Down; FDR = 0.0226; PValue = 0.00604; mean CPM = 2.573; heat shock 70kDa protein 6 (HSP70B')" ID="ID_1299255442" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1478910257" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR2: 1.23-fold Up; FDR = 0.0258; PValue = 0.00707; mean CPM = 46.52; interferon gamma receptor 2 (interferon gamma transducer 1)" ID="ID_1321110317" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1353948964" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DNAJB1: 1.18-fold Up; FDR = 0.0756; PValue = 0.0252; mean CPM = 33.66; DnaJ (Hsp40) homolog, subfamily B, member 1" ID="ID_372421297" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NXT1: 1.29-fold Up; FDR = 0.0866; PValue = 0.0295; mean CPM = 6.865; NTF2-like export factor 1" ID="ID_1860120357" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_1371580886" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_857737585" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FDPS: 1.15-fold Down; FDR = 0.126; PValue = 0.0464; mean CPM = 49.16; farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)" ID="ID_880645054" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_883911265" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_694877234" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_738011179" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000039103: 1.67-fold Down; FDR = 0.221; PValue = 0.0927; mean CPM = 1.310; Uncharacterized protein" ID="ID_491439240" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PYCARD: 1.38-fold Down; FDR = 0.241; PValue = 0.103; mean CPM = 3.110; PYD and CARD domain containing" ID="ID_735599855" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_738436712" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLRP3: 1.84-fold Down; FDR = 0.32; PValue = 0.147; mean CPM = 0.9630; NLR family, pyrin domain containing 3" ID="ID_990419437" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_64556311" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF10B: 1.13-fold Down; FDR = 0.343; PValue = 0.16; mean CPM = 40.59; tumor necrosis factor receptor superfamily, member 10b" ID="ID_1620265388" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_276704178" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TICAM1: 1.11-fold Down; FDR = 0.398; PValue = 0.192; mean CPM = 26.73; toll-like receptor adaptor molecule 1" ID="ID_35421653" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_1378241893" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1722540610" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK12: 1.19-fold Down; FDR = 0.422; PValue = 0.208; mean CPM = 6.569; mitogen-activated protein kinase 12" ID="ID_1038480600" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1449727083" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2AK1: 1.09-fold Up; FDR = 0.499; PValue = 0.258; mean CPM = 34.88; Uncharacterized protein" ID="ID_906036519" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_162245870" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK13: 1.22-fold Down; FDR = 0.536; PValue = 0.284; mean CPM = 3.100; mitogen-activated protein kinase 13" ID="ID_570501327" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_600082587" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2AK4: 1.06-fold Up; FDR = 0.681; PValue = 0.391; mean CPM = 104.8; eukaryotic translation initiation factor 2 alpha kinase 4" ID="ID_722043450" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NUP98: 1.06-fold Up; FDR = 0.704; PValue = 0.41; mean CPM = 125.0; nucleoporin 98kDa" ID="ID_1278031624" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNB1: 1.79-fold Up; FDR = 0.731; PValue = 0.433; mean CPM = 0.8526; interferon, beta 1, fibroblast" ID="ID_1784491389" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF10A: 1.06-fold Down; FDR = 0.732; PValue = 0.434; mean CPM = 42.75; tumor necrosis factor receptor superfamily, member 10a" ID="ID_1636044365" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYCS: 1.05-fold Up; FDR = 0.854; PValue = 0.565; mean CPM = 93.43; cytochrome c, somatic" ID="ID_244991036" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000040219: 1.08-fold Up; FDR = 0.86; PValue = 0.575; mean CPM = 8.818; Uncharacterized protein" ID="ID_299607600" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1094922904" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR7: 1.37-fold Down; FDR = 0.878; PValue = 0.597; mean CPM = 0.8402; toll-like receptor 7" ID="ID_1069158563" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NXF2B: 1.25-fold Up; FDR = 0.881; PValue = 0.601; mean CPM = 0.9156; nuclear RNA export factor 2B" ID="ID_708953912" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_964817431" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAE1: 1.03-fold Up; FDR = 0.92; PValue = 0.723; mean CPM = 25.49; RAE1 RNA export 1 homolog (S. pombe)" ID="ID_106383532" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKE: 1.03-fold Up; FDR = 0.929; PValue = 0.737; mean CPM = 21.61; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon" ID="ID_594987470" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DNAJC3: 1.02-fold Down; FDR = 0.931; PValue = 0.742; mean CPM = 43.82; DnaJ (Hsp40) homolog, subfamily C, member 3" ID="ID_749275001" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FASLG: 1.2-fold Down; FDR = 0.941; PValue = 0.757; mean CPM = 0.8088; Fas ligand (TNF superfamily, member 6)" ID="ID_1396158695" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_1323581069" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000009289: 1.07-fold Up; FDR = 0.963; PValue = 0.798; mean CPM = 2.536; Uncharacterized protein" ID="ID_31797375" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_1097728080" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NXF3: 1.03-fold Up; FDR = 1; PValue = 0.882; mean CPM = 2.392; nuclear RNA export factor 3" ID="ID_1550595908" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP9: 1.01-fold Up; FDR = 1; PValue = 0.908; mean CPM = 19.86; caspase 9, apoptosis-related cysteine peptidase" ID="ID_275253519" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_1761457456" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Pantothenate and CoA biosynthesis: Upregulated, FDR = 0.103, PValue = 0.00554" ID="ID_1931075914" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="DPYD: 4.49-fold Up; FDR = 3.79e-15; PValue = 3.7e-17; mean CPM = 16.01; dihydropyrimidine dehydrogenase" ID="ID_1780904117" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPCS: 1.92-fold Up; FDR = 4.36e-09; PValue = 1.73e-10; mean CPM = 40.39; phosphopantothenoylcysteine synthetase" ID="ID_1848233573" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AASDHPPT: 1.74-fold Up; FDR = 8.2e-09; PValue = 3.45e-10; mean CPM = 30.56; aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase" ID="ID_1560320990" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DPYS: 3.77-fold Up; FDR = 9.52e-09; PValue = 4.08e-10; mean CPM = 3.786; dihydropyrimidinase" ID="ID_1308812686" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="UPB1: 2.85-fold Up; FDR = 3.25e-05; PValue = 3.48e-06; mean CPM = 5.162; Uncharacterized protein" ID="ID_909565533" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PANK2: 1.39-fold Up; FDR = 0.000235; PValue = 3.28e-05; mean CPM = 26.85; pantothenate kinase 2" ID="ID_1533038725" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COASY: 1.22-fold Up; FDR = 0.0233; PValue = 0.00628; mean CPM = 50.97; CoA synthase" ID="ID_1506947860" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PANK4: 1.14-fold Down; FDR = 0.199; PValue = 0.0817; mean CPM = 36.45; pantothenate kinase 4" ID="ID_538323961" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENPP3: 1.58-fold Down; FDR = 0.218; PValue = 0.0912; mean CPM = 1.719; ectonucleotide pyrophosphatase/phosphodiesterase 3" ID="ID_958888045" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENPP1: 1.2-fold Down; FDR = 0.346; PValue = 0.162; mean CPM = 147.6; ectonucleotide pyrophosphatase/phosphodiesterase 1" ID="ID_1480737200" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PANK3: 1.09-fold Down; FDR = 0.544; PValue = 0.289; mean CPM = 24.42; pantothenate kinase 3" ID="ID_464579446" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VNN2: 1.26-fold Up; FDR = 0.925; PValue = 0.731; mean CPM = 0.8160; vanin 2" ID="ID_819728440" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPCDC: 1.03-fold Up; FDR = 0.943; PValue = 0.763; mean CPM = 7.496; phosphopantothenoylcysteine decarboxylase" ID="ID_1447472995" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PANK1: 1.01-fold Up; FDR = 1; PValue = 0.953; mean CPM = 3.405; pantothenate kinase 1" ID="ID_923978481" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VNN1: 1.01-fold Down; FDR = 1; PValue = 0.998; mean CPM = 0.8178; vanin 1" ID="ID_129996227" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Cytosolic DNA-sensing pathway: Upregulated, FDR = 0.103, PValue = 0.00595" ID="ID_856271709" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="AIM2: 7.87-fold Up; FDR = 4.34e-20; PValue = 1.57e-22; mean CPM = 34.80; absent in melanoma 2" ID="ID_323698501" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DDX58: 6.4-fold Up; FDR = 5.12e-18; PValue = 3.06e-20; mean CPM = 86.14; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58" ID="ID_35690454" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF7: 14.8-fold Up; FDR = 7.66e-18; PValue = 4.82e-20; mean CPM = 11.54; Macaca mulatta interferon regulatory factor 7 (IRF7), mRNA." ID="ID_1647790487" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK3: 3.47-fold Up; FDR = 2.3e-12; PValue = 4.07e-14; mean CPM = 12.05; receptor-interacting serine-threonine kinase 3" ID="ID_458331099" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MB21D1: 3.62-fold Up; FDR = 5.31e-10; PValue = 1.69e-11; mean CPM = 10.27; Mab-21 domain containing 1" ID="ID_1502592122" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAVS: 1.92-fold Down; FDR = 2.7e-09; PValue = 1.02e-10; mean CPM = 29.16; mitochondrial antiviral signaling protein" ID="ID_665103164" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_1238981550" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1875104837" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZBP1: 4.36-fold Up; FDR = 0.00021; PValue = 2.88e-05; mean CPM = 1.491; Z-DNA binding protein 1" ID="ID_1184919364" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBK1: 1.3-fold Up; FDR = 0.00337; PValue = 0.000674; mean CPM = 30.46; TANK-binding kinase 1" ID="ID_68170697" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1621986967" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMEM173: 1.25-fold Up; FDR = 0.00837; PValue = 0.00192; mean CPM = 219.1; transmembrane protein 173" ID="ID_546757342" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1830785634" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_333404575" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PYCARD: 1.38-fold Down; FDR = 0.241; PValue = 0.103; mean CPM = 3.110; PYD and CARD domain containing" ID="ID_1848119941" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_423551279" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKE: 1.03-fold Up; FDR = 0.929; PValue = 0.737; mean CPM = 21.61; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon" ID="ID_146367380" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_875946463" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Staphylococcus aureus infection: Upregulated, FDR = 0.103, PValue = 0.00606" ID="ID_1515777040" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="ICAM1: 24.6-fold Up; FDR = 2.39e-17; PValue = 1.64e-19; mean CPM = 232.4; intercellular adhesion molecule 1" ID="ID_58272808" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C2: 4.8-fold Up; FDR = 3.21e-17; PValue = 2.26e-19; mean CPM = 200.3; Uncharacterized protein" ID="ID_1995866031" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CFH: 2.48-fold Up; FDR = 4.03e-10; PValue = 1.24e-11; mean CPM = 1912; complement factor H" ID="ID_274744897" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C3AR1: 4.66-fold Up; FDR = 1e-06; PValue = 7.26e-08; mean CPM = 15.65; complement component 3a receptor 1" ID="ID_1077905694" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C5AR1: 3.36-fold Up; FDR = 3.05e-05; PValue = 3.23e-06; mean CPM = 14.55; complement component 5a receptor 1" ID="ID_1163167679" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB2: 1.55-fold Down; FDR = 0.0187; PValue = 0.00485; mean CPM = 34.87; Integrin beta" ID="ID_1065009620" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C5: 2.29-fold Up; FDR = 0.0212; PValue = 0.00561; mean CPM = 1.418; complement component 5" ID="ID_1849525559" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C1QB: 2.62-fold Up; FDR = 0.0887; PValue = 0.0304; mean CPM = 1.092; complement component 1, q subcomponent, B chain" ID="ID_1059247016" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C1QC: 2.02-fold Up; FDR = 0.203; PValue = 0.0839; mean CPM = 1.322; complement component 1, q subcomponent, C chain" ID="ID_1264816008" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MASP1: 1.46-fold Down; FDR = 0.264; PValue = 0.115; mean CPM = 4.467; mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)" ID="ID_1386252546" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MASP2: 1.23-fold Down; FDR = 0.546; PValue = 0.291; mean CPM = 3.073; mannan-binding lectin serine peptidase 2" ID="ID_359984410" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000000985: 1.2-fold Up; FDR = 0.569; PValue = 0.307; mean CPM = 11.32; Uncharacterized protein" ID="ID_796698348" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAM: 1.44-fold Down; FDR = 0.73; PValue = 0.432; mean CPM = 0.9052; integrin, alpha M (complement component 3 receptor 3 subunit)" ID="ID_598836421" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MBL2: 1.3-fold Up; FDR = 0.85; PValue = 0.561; mean CPM = 0.7954; mannose-binding lectin (protein C) 2, soluble (opsonic defect)" ID="ID_296038390" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTAFR: 1.39-fold Down; FDR = 0.906; PValue = 0.67; mean CPM = 0.8209; platelet-activating factor receptor" ID="ID_1882169032" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLG: 1.41-fold Down; FDR = 0.937; PValue = 0.751; mean CPM = 0.8390; plasminogen" ID="ID_680459017" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SELP: 1.2-fold Down; FDR = 0.942; PValue = 0.76; mean CPM = 0.8693; selectin P (granule membrane protein 140kDa, antigen CD62)" ID="ID_1731877645" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAL: 1.03-fold Up; FDR = 1; PValue = 0.95; mean CPM = 1.035; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)" ID="ID_1553246702" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL10: 1.21-fold Down; FDR = 1; PValue = 0.964; mean CPM = 0.8614; interleukin 10" ID="ID_1069187631" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Pertussis: Upregulated, FDR = 0.103, PValue = 0.00646" ID="ID_720341030" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="SERPING1: 17.2-fold Up; FDR = 2.79e-22; PValue = 6.42e-25; mean CPM = 499.3; serpin peptidase inhibitor, clade G (C1 inhibitor), member 1" ID="ID_1597610265" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF1: 18.6-fold Up; FDR = 1.53e-21; PValue = 4.24e-24; mean CPM = 240.7; interferon regulatory factor 1" ID="ID_1975477326" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C2: 4.8-fold Up; FDR = 3.21e-17; PValue = 2.26e-19; mean CPM = 200.3; Uncharacterized protein" ID="ID_637032215" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR4: 3.45-fold Up; FDR = 3.1e-09; PValue = 1.19e-10; mean CPM = 7.456; Macaca mulatta toll-like receptor 4 (TLR4), mRNA." ID="ID_1232518353" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF8: 11.4-fold Up; FDR = 6e-09; PValue = 2.46e-10; mean CPM = 5.558; interferon regulatory factor 8" ID="ID_1027572114" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CFL2: 1.88-fold Down; FDR = 1.06e-08; PValue = 4.59e-10; mean CPM = 58.30; cofilin 2 (muscle)" ID="ID_1369308971" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK4: 1.8-fold Up; FDR = 3.31e-08; PValue = 1.64e-09; mean CPM = 12.89; interleukin-1 receptor-associated kinase 4" ID="ID_1993192839" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1182200983" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1025206708" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAI1: 1.47-fold Up; FDR = 5.94e-05; PValue = 6.9e-06; mean CPM = 97.19; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1" ID="ID_1028213689" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOD1: 1.63-fold Up; FDR = 0.000193; PValue = 2.61e-05; mean CPM = 58.36; nucleotide-binding oligomerization domain containing 1" ID="ID_1810087104" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHOA: 1.28-fold Down; FDR = 0.00295; PValue = 0.000575; mean CPM = 277.8; ras homolog gene family, member A" ID="ID_966632544" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAI3: 1.26-fold Up; FDR = 0.00487; PValue = 0.00103; mean CPM = 113.8; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3" ID="ID_42760103" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_491847977" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12A: 2.09-fold Up; FDR = 0.00924; PValue = 0.00215; mean CPM = 2.872; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)" ID="ID_5592804" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_416592484" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C5: 2.29-fold Up; FDR = 0.0212; PValue = 0.00561; mean CPM = 1.418; complement component 5" ID="ID_1018606572" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_626562620" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1092736177" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C1QB: 2.62-fold Up; FDR = 0.0887; PValue = 0.0304; mean CPM = 1.092; complement component 1, q subcomponent, B chain" ID="ID_1138168782" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_1878687731" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAI2: 1.15-fold Down; FDR = 0.134; PValue = 0.0501; mean CPM = 356.3; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2" ID="ID_1207167337" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_535708522" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C1QC: 2.02-fold Up; FDR = 0.203; PValue = 0.0839; mean CPM = 1.322; complement component 1, q subcomponent, C chain" ID="ID_469985771" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PYCARD: 1.38-fold Down; FDR = 0.241; PValue = 0.103; mean CPM = 3.110; PYD and CARD domain containing" ID="ID_291218377" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1A: 1.5-fold Up; FDR = 0.315; PValue = 0.144; mean CPM = 155.4; interleukin 1, alpha" ID="ID_1944977831" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLRP3: 1.84-fold Down; FDR = 0.32; PValue = 0.147; mean CPM = 0.9630; NLR family, pyrin domain containing 3" ID="ID_26410710" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TICAM1: 1.11-fold Down; FDR = 0.398; PValue = 0.192; mean CPM = 26.73; toll-like receptor adaptor molecule 1" ID="ID_1034483983" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_788940014" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1883165144" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK12: 1.19-fold Down; FDR = 0.422; PValue = 0.208; mean CPM = 6.569; mitogen-activated protein kinase 12" ID="ID_1158226274" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_557249285" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK13: 1.22-fold Down; FDR = 0.536; PValue = 0.284; mean CPM = 3.100; mitogen-activated protein kinase 13" ID="ID_47396933" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_119113938" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C4BPB: 1.43-fold Up; FDR = 0.835; PValue = 0.538; mean CPM = 0.7975; complement component 4 binding protein, beta" ID="ID_1772328033" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TIRAP: 1.07-fold Up; FDR = 0.841; PValue = 0.548; mean CPM = 8.693; Macaca mulatta toll-interleukin 1 receptor (TIR) domain containing adaptor protein (TIRAP), mRNA." ID="ID_1593552688" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK1: 1.04-fold Down; FDR = 0.885; PValue = 0.606; mean CPM = 41.54; interleukin-1 receptor-associated kinase 1" ID="ID_1527922980" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOS2: 1.4-fold Down; FDR = 0.917; PValue = 0.718; mean CPM = 0.8546; nitric oxide synthase 2, inducible" ID="ID_424384522" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C4BPA: 1.25-fold Down; FDR = 0.964; PValue = 0.801; mean CPM = 0.8114; complement component 4 binding protein, alpha" ID="ID_1060741748" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12B: 1.07-fold Up; FDR = 0.983; PValue = 0.831; mean CPM = 0.8197; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)" ID="ID_1596000834" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate: Downregulated, FDR = 0.103, PValue = 0.00669" ID="ID_1383591819" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CHPF2: 1.6-fold Down; FDR = 1.29e-09; PValue = 4.48e-11; mean CPM = 144.9; chondroitin polymerizing factor 2" ID="ID_1446853343" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XYLT2: 1.6-fold Down; FDR = 1.88e-08; PValue = 8.77e-10; mean CPM = 40.83; xylosyltransferase II" ID="ID_472190469" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSGALNACT1: 1.65-fold Down; FDR = 5.73e-05; PValue = 6.62e-06; mean CPM = 61.96; chondroitin sulfate N-acetylgalactosaminyltransferase 1" ID="ID_451725208" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHPF: 1.43-fold Down; FDR = 0.000508; PValue = 7.77e-05; mean CPM = 453.1; chondroitin polymerizing factor" ID="ID_989196146" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHSY3: 1.83-fold Down; FDR = 0.000714; PValue = 0.000115; mean CPM = 8.647; chondroitin sulfate synthase 3" ID="ID_1290201217" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="B4GALT7: 1.27-fold Down; FDR = 0.0118; PValue = 0.00284; mean CPM = 25.41; xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I)" ID="ID_164875757" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="B3GAT3: 1.25-fold Down; FDR = 0.012; PValue = 0.00289; mean CPM = 36.73; beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)" ID="ID_1738501681" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHSY1: 1.22-fold Down; FDR = 0.0208; PValue = 0.0055; mean CPM = 95.32; chondroitin sulfate synthase 1" ID="ID_1000323899" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XYLT1: 1.42-fold Down; FDR = 0.0861; PValue = 0.0293; mean CPM = 25.07; Xylosyltransferase 1" ID="ID_156086838" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSGALNACT2: 1.02-fold Down; FDR = 0.939; PValue = 0.754; mean CPM = 79.15; chondroitin sulfate N-acetylgalactosaminyltransferase 2" ID="ID_1413069642" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Lipoic acid metabolism: Upregulated, FDR = 0.117, PValue = 0.00825" ID="ID_1420477255" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="LIPT1: 3.57-fold Up; FDR = 1.5e-07; PValue = 8.76e-09; mean CPM = 3.209; lipoyltransferase 1" ID="ID_1044345317" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LIPT2: 1.55-fold Up; FDR = 0.000223; PValue = 3.07e-05; mean CPM = 11.87; lipoyl(octanoyl) transferase 2 (putative)" ID="ID_932205306" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LIAS: 1.31-fold Up; FDR = 0.0288; PValue = 0.00801; mean CPM = 11.32; lipoic acid synthetase" ID="ID_1905812631" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Dorso-ventral axis formation: Upregulated, FDR = 0.281, PValue = 0.0215" ID="ID_1563966628" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="ETV7: 4.5-fold Up; FDR = 1.81e-17; PValue = 1.22e-19; mean CPM = 17.33; ets variant 7" ID="ID_352281887" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_1915210602" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGFR: 1.84-fold Up; FDR = 6.71e-09; PValue = 2.77e-10; mean CPM = 68.58; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)" ID="ID_1096254495" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_101181668" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_999309386" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KRAS: 1.35-fold Down; FDR = 0.0401; PValue = 0.0119; mean CPM = 13.10; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog" ID="ID_84992747" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ETS1: 1.16-fold Up; FDR = 0.0996; PValue = 0.0348; mean CPM = 94.27; v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)" ID="ID_1466607541" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS2: 1.17-fold Up; FDR = 0.1; PValue = 0.0353; mean CPM = 31.79; son of sevenless homolog 2 (Drosophila)" ID="ID_1435912457" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1994859082" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_64579162" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ETV6: 1.08-fold Down; FDR = 0.568; PValue = 0.307; mean CPM = 30.13; ets variant 6" ID="ID_1642864142" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ETS2: 1.04-fold Down; FDR = 0.92; PValue = 0.722; mean CPM = 25.97; v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)" ID="ID_1520291228" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Hepatitis C: Upregulated, FDR = 0.336, PValue = 0.0282" ID="ID_335757423" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="IRF1: 18.6-fold Up; FDR = 1.53e-21; PValue = 4.24e-24; mean CPM = 240.7; interferon regulatory factor 1" ID="ID_993891184" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR3: 10.3-fold Up; FDR = 1.95e-21; PValue = 5.6e-24; mean CPM = 35.70; toll-like receptor 3" ID="ID_1911929732" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFIT1: 52.1-fold Up; FDR = 1.76e-20; PValue = 6.3e-23; mean CPM = 46.34; interferon-induced protein with tetratricopeptide repeats 1" ID="ID_412726749" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF9: 3.85-fold Up; FDR = 2.6e-19; PValue = 1.12e-21; mean CPM = 106.4; interferon regulatory factor 9" ID="ID_1313200838" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT2: 2.67-fold Up; FDR = 8.02e-19; PValue = 4.03e-21; mean CPM = 185.6; signal transducer and activator of transcription 2, 113kDa" ID="ID_709728321" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_150925414" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DDX58: 6.4-fold Up; FDR = 5.12e-18; PValue = 3.06e-20; mean CPM = 86.14; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58" ID="ID_1742893076" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2AK2: 3.01-fold Up; FDR = 6.08e-18; PValue = 3.74e-20; mean CPM = 47.85; eukaryotic translation initiation factor 2-alpha kinase 2" ID="ID_564718331" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF7: 14.8-fold Up; FDR = 7.66e-18; PValue = 4.82e-20; mean CPM = 11.54; Macaca mulatta interferon regulatory factor 7 (IRF7), mRNA." ID="ID_1351895262" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAVS: 1.92-fold Down; FDR = 2.7e-09; PValue = 1.02e-10; mean CPM = 29.16; mitochondrial antiviral signaling protein" ID="ID_333425401" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_191261958" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGFR: 1.84-fold Up; FDR = 6.71e-09; PValue = 2.77e-10; mean CPM = 68.58; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)" ID="ID_1635882985" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_1105743131" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_886382352" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFIT1L: 11.9-fold Up; FDR = 3.7e-08; PValue = 1.87e-09; mean CPM = 2.353; interferon-induced protein with tetratricopeptide repeats 1B" ID="ID_234846339" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1711413184" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_581118059" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_1482501443" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR2: 1.74-fold Up; FDR = 1.85e-06; PValue = 1.44e-07; mean CPM = 26.05; interferon (alpha, beta and omega) receptor 2" ID="ID_940820764" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_704596690" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2AK3: 1.59-fold Down; FDR = 2.47e-06; PValue = 1.96e-07; mean CPM = 33.81; eukaryotic translation initiation factor 2-alpha kinase 3" ID="ID_1007525351" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R1B: 1.39-fold Down; FDR = 4.37e-05; PValue = 4.86e-06; mean CPM = 233.1; protein phosphatase 2, regulatory subunit A, beta" ID="ID_923714511" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2S1: 1.42-fold Up; FDR = 5.59e-05; PValue = 6.42e-06; mean CPM = 79.87; eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa" ID="ID_347281651" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2CB: 1.35-fold Up; FDR = 0.000215; PValue = 2.96e-05; mean CPM = 59.68; protein phosphatase 2, catalytic subunit, beta isozyme" ID="ID_439941370" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R2B: 7.66-fold Down; FDR = 0.000564; PValue = 8.78e-05; mean CPM = 4.510; protein phosphatase 2, regulatory subunit B, beta" ID="ID_788992621" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAD: 1.36-fold Down; FDR = 0.000605; PValue = 9.52e-05; mean CPM = 48.46; BCL2-associated agonist of cell death" ID="ID_1013003018" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS3: 1.69-fold Up; FDR = 0.000994; PValue = 0.000167; mean CPM = 37.76; suppressor of cytokine signaling 3" ID="ID_1993554347" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIAS1: 1.3-fold Up; FDR = 0.00259; PValue = 0.000498; mean CPM = 29.99; protein inhibitor of activated STAT, 1" ID="ID_442871525" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBK1: 1.3-fold Up; FDR = 0.00337; PValue = 0.000674; mean CPM = 30.46; TANK-binding kinase 1" ID="ID_221908865" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_953464189" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_986070670" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR1: 1.27-fold Up; FDR = 0.0101; PValue = 0.00237; mean CPM = 82.39; Uncharacterized protein" ID="ID_1701258399" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYK2: 1.24-fold Down; FDR = 0.0142; PValue = 0.00354; mean CPM = 42.58; tyrosine kinase 2" ID="ID_280550320" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_959393644" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1685463266" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRADD: 1.22-fold Up; FDR = 0.0319; PValue = 0.00907; mean CPM = 34.75; TNFRSF1A-associated via death domain" ID="ID_1491473880" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDPK1: 1.24-fold Down; FDR = 0.0361; PValue = 0.0105; mean CPM = 17.53; 3-phosphoinositide dependent protein kinase-1" ID="ID_1001476957" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1613649041" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KRAS: 1.35-fold Down; FDR = 0.0401; PValue = 0.0119; mean CPM = 13.10; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog" ID="ID_1893687629" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NRAS: 1.2-fold Down; FDR = 0.0546; PValue = 0.017; mean CPM = 32.39; neuroblastoma RAS viral (v-ras) oncogene homolog" ID="ID_33965148" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_1060688529" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_925061264" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS2: 1.17-fold Up; FDR = 0.1; PValue = 0.0353; mean CPM = 31.79; son of sevenless homolog 2 (Drosophila)" ID="ID_1152573048" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_1992935493" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_37286452" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_1316738859" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1252726320" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BRAF: 1.14-fold Down; FDR = 0.228; PValue = 0.0964; mean CPM = 24.98; v-raf murine sarcoma viral oncogene homolog B1" ID="ID_1520677089" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1A: 1.16-fold Down; FDR = 0.28; PValue = 0.124; mean CPM = 363.2; Cyclin-dependent kinase inhibitor 1; Uncharacterized protein" ID="ID_482415684" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_351204597" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1A: 1.11-fold Up; FDR = 0.297; PValue = 0.134; mean CPM = 134.7; tumor necrosis factor receptor superfamily, member 1A" ID="ID_356052275" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_1254134194" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP53: 1.11-fold Down; FDR = 0.364; PValue = 0.172; mean CPM = 33.25; tumor protein p53" ID="ID_1534212529" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1602287902" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R2C: 1.48-fold Up; FDR = 0.391; PValue = 0.188; mean CPM = 1.318; protein phosphatase 2, regulatory subunit B, gamma" ID="ID_1977149851" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TICAM1: 1.11-fold Down; FDR = 0.398; PValue = 0.192; mean CPM = 26.73; toll-like receptor adaptor molecule 1" ID="ID_629382543" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_360455129" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_866314861" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK12: 1.19-fold Down; FDR = 0.422; PValue = 0.208; mean CPM = 6.569; mitogen-activated protein kinase 12" ID="ID_784273895" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1708663707" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2AK1: 1.09-fold Up; FDR = 0.499; PValue = 0.258; mean CPM = 34.88; Uncharacterized protein" ID="ID_651756188" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_77124645" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK13: 1.22-fold Down; FDR = 0.536; PValue = 0.284; mean CPM = 3.100; mitogen-activated protein kinase 13" ID="ID_1751021594" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF3: 1.07-fold Up; FDR = 0.611; PValue = 0.338; mean CPM = 34.56; TNF receptor-associated factor 3" ID="ID_1032552702" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2AK4: 1.06-fold Up; FDR = 0.681; PValue = 0.391; mean CPM = 104.8; eukaryotic translation initiation factor 2 alpha kinase 4" ID="ID_552389798" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNB1: 1.79-fold Up; FDR = 0.731; PValue = 0.433; mean CPM = 0.8526; interferon, beta 1, fibroblast" ID="ID_1408779056" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R2A: 1.06-fold Down; FDR = 0.733; PValue = 0.435; mean CPM = 44.53; protein phosphatase 2, regulatory subunit B, alpha" ID="ID_379256592" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2CA: 1.05-fold Up; FDR = 0.8; PValue = 0.497; mean CPM = 62.78; protein phosphatase 2, catalytic subunit, alpha isozyme" ID="ID_179554796" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA6: 1.41-fold Down; FDR = 0.807; PValue = 0.504; mean CPM = 0.8019; interferon, alpha 6" ID="ID_26283562" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF3E: 1.04-fold Up; FDR = 0.836; PValue = 0.542; mean CPM = 131.3; eukaryotic translation initiation factor 3, subunit E" ID="ID_82337546" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1653328076" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_582475549" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R2D: 1.04-fold Down; FDR = 0.899; PValue = 0.629; mean CPM = 19.98; protein phosphatase 2, regulatory subunit B, delta isoform" ID="ID_30623773" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA13: 1.13-fold Up; FDR = 0.908; PValue = 0.677; mean CPM = 0.7960; interferon, alpha 13" ID="ID_933857432" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA8: 1.13-fold Down; FDR = 0.911; PValue = 0.702; mean CPM = 0.7910; interferon, alpha 8" ID="ID_1817182665" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKE: 1.03-fold Up; FDR = 0.929; PValue = 0.737; mean CPM = 21.61; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon" ID="ID_1472800963" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_923488872" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA14: 1.22-fold Up; FDR = 0.965; PValue = 0.802; mean CPM = 0.8654; interferon, alpha 14" ID="ID_1281375104" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA4: 1.28-fold Down; FDR = 0.983; PValue = 0.829; mean CPM = 0.8584; interferon, alpha 4" ID="ID_451290093" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGF: 1.06-fold Down; FDR = 1; PValue = 0.885; mean CPM = 0.8917; epidermal growth factor" ID="ID_553623025" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA1: No Change; FDR = 1; PValue = 0.998; mean CPM = 0.8014; interferon, alpha 1" ID="ID_1686753463" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg NF-kappa B signaling pathway: Upregulated, FDR = 0.336, PValue = 0.0336" ID="ID_1031947310" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TNFSF13B: 123-fold Up; FDR = 9.32e-25; PValue = 7.44e-28; mean CPM = 49.02; tumor necrosis factor (ligand) superfamily, member 13b" ID="ID_1091158363" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRIM25: 3.78-fold Up; FDR = 3.13e-19; PValue = 1.41e-21; mean CPM = 121.6; tripartite motif-containing 25" ID="ID_503381867" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DDX58: 6.4-fold Up; FDR = 5.12e-18; PValue = 3.06e-20; mean CPM = 86.14; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58" ID="ID_507308513" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICAM1: 24.6-fold Up; FDR = 2.39e-17; PValue = 1.64e-19; mean CPM = 232.4; intercellular adhesion molecule 1" ID="ID_1585058802" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC2: 1.96-fold Up; FDR = 1.01e-10; PValue = 2.62e-12; mean CPM = 53.58; baculoviral IAP repeat-containing 2" ID="ID_296542965" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLAU: 3.37-fold Down; FDR = 1.56e-10; PValue = 4.33e-12; mean CPM = 18.78; plasminogen activator, urokinase" ID="ID_503819670" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL13: 12.3-fold Up; FDR = 4.33e-10; PValue = 1.35e-11; mean CPM = 3.824; chemokine (C-C motif) ligand 13" ID="ID_32033775" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CFLAR: 1.87-fold Up; FDR = 5.09e-10; PValue = 1.61e-11; mean CPM = 103.3; CASP8 and FADD-like apoptosis regulator" ID="ID_1687156035" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2A1: 5.05-fold Up; FDR = 1.06e-09; PValue = 3.61e-11; mean CPM = 10.70; BCL2-related protein A1" ID="ID_1494127729" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR4: 3.45-fold Up; FDR = 3.1e-09; PValue = 1.19e-10; mean CPM = 7.456; Macaca mulatta toll-like receptor 4 (TLR4), mRNA." ID="ID_1683205006" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_1419781835" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK4: 1.8-fold Up; FDR = 3.31e-08; PValue = 1.64e-09; mean CPM = 12.89; interleukin-1 receptor-associated kinase 4" ID="ID_841155111" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1336924182" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD14: 2.75-fold Down; FDR = 6.54e-07; PValue = 4.46e-08; mean CPM = 5.195; CD14 molecule" ID="ID_149389654" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L1: 1.51-fold Up; FDR = 9.13e-07; PValue = 6.52e-08; mean CPM = 66.15; Bcl-2-like protein 1; Bcl-2-like protein 1 isoform 1; Uncharacterized protein" ID="ID_1216440199" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC3: 2.79-fold Up; FDR = 1.74e-06; PValue = 1.32e-07; mean CPM = 95.34; baculoviral IAP repeat-containing 3" ID="ID_1605885610" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF1: 2.6-fold Down; FDR = 1.48e-05; PValue = 1.46e-06; mean CPM = 20.19; TNF receptor-associated factor 1" ID="ID_1560402964" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFAIP3: 1.79-fold Up; FDR = 3.14e-05; PValue = 3.34e-06; mean CPM = 52.47; tumor necrosis factor, alpha-induced protein 3" ID="ID_463195946" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1R1: 1.6-fold Up; FDR = 3.35e-05; PValue = 3.61e-06; mean CPM = 123.7; interleukin 1 receptor, type I" ID="ID_1845501510" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_1233213835" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP2: 1.45-fold Up; FDR = 0.000179; PValue = 2.4e-05; mean CPM = 65.31; TGF-beta activated kinase 1/MAP3K7 binding protein 2" ID="ID_742124414" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTGS2: 2.02-fold Up; FDR = 0.000254; PValue = 3.59e-05; mean CPM = 314.5; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)" ID="ID_741311473" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP3: 1.5-fold Up; FDR = 0.000276; PValue = 3.92e-05; mean CPM = 11.67; TGF-beta activated kinase 1/MAP3K7 binding protein 3" ID="ID_1087281355" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40: 2.76-fold Up; FDR = 0.00039; PValue = 5.79e-05; mean CPM = 9.139; CD40 molecule, TNF receptor superfamily member 5" ID="ID_317142263" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG1: 1.31-fold Down; FDR = 0.00352; PValue = 0.000707; mean CPM = 53.66; phospholipase C, gamma 1" ID="ID_334836965" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_824690894" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K14: 1.47-fold Down; FDR = 0.00704; PValue = 0.00157; mean CPM = 9.470; mitogen-activated protein kinase kinase kinase 14" ID="ID_1769102236" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GADD45B: 1.49-fold Down; FDR = 0.0082; PValue = 0.00187; mean CPM = 175.6; growth arrest and DNA-damage-inducible, beta" ID="ID_374438253" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BLNK: 2.61-fold Up; FDR = 0.012; PValue = 0.00288; mean CPM = 1.254; Uncharacterized protein" ID="ID_1082531986" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSNK2A2: 1.28-fold Up; FDR = 0.0129; PValue = 0.00314; mean CPM = 19.86; casein kinase 2, alpha prime polypeptide" ID="ID_1345442774" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL8: 2.33-fold Up; FDR = 0.0209; PValue = 0.00552; mean CPM = 2326; interleukin 8" ID="ID_172934098" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CARD11: 1.31-fold Down; FDR = 0.0223; PValue = 0.00597; mean CPM = 58.32; caspase recruitment domain family, member 11" ID="ID_306369728" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRADD: 1.22-fold Up; FDR = 0.0319; PValue = 0.00907; mean CPM = 34.75; TNFRSF1A-associated via death domain" ID="ID_1802932319" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VCAM1: 1.53-fold Up; FDR = 0.0353; PValue = 0.0102; mean CPM = 110.0; vascular cell adhesion molecule 1" ID="ID_1852437468" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF11: 1.8-fold Up; FDR = 0.039; PValue = 0.0115; mean CPM = 2.535; tumor necrosis factor (ligand) superfamily, member 11" ID="ID_68926336" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_867346235" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELB: 1.22-fold Down; FDR = 0.0606; PValue = 0.0193; mean CPM = 26.64; v-rel reticuloendotheliosis viral oncogene homolog B" ID="ID_1123681074" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_1217283943" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XIAP: 1.17-fold Up; FDR = 0.177; PValue = 0.0706; mean CPM = 19.21; X-linked inhibitor of apoptosis" ID="ID_1458768574" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAT: 1.44-fold Down; FDR = 0.234; PValue = 0.0996; mean CPM = 1.871; linker for activation of T cells" ID="ID_1086292190" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1A: 1.11-fold Up; FDR = 0.297; PValue = 0.134; mean CPM = 134.7; tumor necrosis factor receptor superfamily, member 1A" ID="ID_693122583" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP1: 1.12-fold Down; FDR = 0.351; PValue = 0.165; mean CPM = 17.96; TGF-beta activated kinase 1/MAP3K7 binding protein 1" ID="ID_1339601093" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2: 1.48-fold Up; FDR = 0.384; PValue = 0.184; mean CPM = 1.344; Uncharacterized protein" ID="ID_419262289" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TICAM1: 1.11-fold Down; FDR = 0.398; PValue = 0.192; mean CPM = 26.73; toll-like receptor adaptor molecule 1" ID="ID_1616703687" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL12: 1.27-fold Down; FDR = 0.488; PValue = 0.251; mean CPM = 4.383; chemokine (C-X-C motif) ligand 12" ID="ID_208698618" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCQ: 1.56-fold Up; FDR = 0.522; PValue = 0.274; mean CPM = 1.047; Uncharacterized protein" ID="ID_119716153" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF3: 1.07-fold Up; FDR = 0.611; PValue = 0.338; mean CPM = 34.56; TNF receptor-associated factor 3" ID="ID_720454904" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_262908076" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF11A: 1.4-fold Down; FDR = 0.676; PValue = 0.388; mean CPM = 0.9723; tumor necrosis factor receptor superfamily, member 11a, NFKB activator" ID="ID_72330494" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LTBR: 1.06-fold Down; FDR = 0.683; PValue = 0.394; mean CPM = 91.13; lymphotoxin beta receptor (TNFR superfamily, member 3)" ID="ID_1311716687" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCB: 1.86-fold Up; FDR = 0.727; PValue = 0.43; mean CPM = 0.8705; protein kinase C, beta" ID="ID_128395349" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TIRAP: 1.07-fold Up; FDR = 0.841; PValue = 0.548; mean CPM = 8.693; Macaca mulatta toll-interleukin 1 receptor (TIR) domain containing adaptor protein (TIRAP), mRNA." ID="ID_710481541" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1693717116" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZAP70: 1.25-fold Down; FDR = 0.872; PValue = 0.59; mean CPM = 0.8996; zeta-chain (TCR) associated protein kinase 70kDa" ID="ID_295738449" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK1: 1.04-fold Down; FDR = 0.885; PValue = 0.606; mean CPM = 41.54; interleukin-1 receptor-associated kinase 1" ID="ID_684963398" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_1460178075" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF14: 1.16-fold Down; FDR = 0.903; PValue = 0.645; mean CPM = 0.7940; tumor necrosis factor (ligand) superfamily, member 14" ID="ID_1784685778" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSNK2B: 1.02-fold Down; FDR = 0.956; PValue = 0.787; mean CPM = 77.24; Casein kinase II subunit beta (CK II beta)(Phosvitin)(Protein G5a)" ID="ID_441150208" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL21: 1.09-fold Down; FDR = 0.972; PValue = 0.813; mean CPM = 1.083; chemokine (C-C motif) ligand 21" ID="ID_1735622090" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_1700235400" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG2: 1.06-fold Up; FDR = 0.985; PValue = 0.834; mean CPM = 2.248; phospholipase C, gamma 2 (phosphatidylinositol-specific)" ID="ID_1042864231" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LTB: 1.01-fold Up; FDR = 1; PValue = 0.935; mean CPM = 0.8459; Lymphotoxin-beta (LT-beta)(Tumor necrosis factor C)(TNF-C)(Tumor necrosis factor ligand superfamily member 3)" ID="ID_282124024" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BTK: No Change; FDR = 1; PValue = 0.965; mean CPM = 0.8336; Bruton agammaglobulinemia tyrosine kinase" ID="ID_690501202" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SYK: 1.11-fold Up; FDR = 1; PValue = 0.977; mean CPM = 0.8420; spleen tyrosine kinase" ID="ID_631959669" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40LG: 1.01-fold Down; FDR = 1; PValue = 0.982; mean CPM = 0.8653; CD40 ligand" ID="ID_374540845" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Systemic lupus erythematosus: Upregulated, FDR = 0.336, PValue = 0.0344" ID="ID_1673734926" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="C2: 4.8-fold Up; FDR = 3.21e-17; PValue = 2.26e-19; mean CPM = 200.3; Uncharacterized protein" ID="ID_1048834405" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40: 2.76-fold Up; FDR = 0.00039; PValue = 5.79e-05; mean CPM = 9.139; CD40 molecule, TNF receptor superfamily member 5" ID="ID_1718545958" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C1QB: 2.62-fold Up; FDR = 0.0887; PValue = 0.0304; mean CPM = 1.092; complement component 1, q subcomponent, B chain" ID="ID_1210079556" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C1QC: 2.02-fold Up; FDR = 0.203; PValue = 0.0839; mean CPM = 1.322; complement component 1, q subcomponent, C chain" ID="ID_553295516" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD80: 1.08-fold Up; FDR = 0.971; PValue = 0.812; mean CPM = 1.157; CD80 molecule" ID="ID_1771009697" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40LG: 1.01-fold Down; FDR = 1; PValue = 0.982; mean CPM = 0.8653; CD40 ligand" ID="ID_1818558326" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD86: 1.01-fold Down; FDR = 1; PValue = 0.99; mean CPM = 0.8012; CD86 molecule" ID="ID_153930337" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Hepatitis B: Upregulated, FDR = 0.336, PValue = 0.0347" ID="ID_566084650" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TLR2: 8.94-fold Up; FDR = 6.97e-23; PValue = 1.25e-25; mean CPM = 18.41; toll-like receptor 2" ID="ID_251863575" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFIH1: 14.7-fold Up; FDR = 8.74e-23; PValue = 1.68e-25; mean CPM = 49.84; interferon induced with helicase C domain 1" ID="ID_1342464873" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR3: 10.3-fold Up; FDR = 1.95e-21; PValue = 5.6e-24; mean CPM = 35.70; toll-like receptor 3" ID="ID_193757806" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT2: 2.67-fold Up; FDR = 8.02e-19; PValue = 4.03e-21; mean CPM = 185.6; signal transducer and activator of transcription 2, 113kDa" ID="ID_1180066714" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1694961248" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DDX58: 6.4-fold Up; FDR = 5.12e-18; PValue = 3.06e-20; mean CPM = 86.14; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58" ID="ID_1529323359" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF7: 14.8-fold Up; FDR = 7.66e-18; PValue = 4.82e-20; mean CPM = 11.54; Macaca mulatta interferon regulatory factor 7 (IRF7), mRNA." ID="ID_493984410" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_451645337" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5A: 2.28-fold Up; FDR = 6.87e-14; PValue = 8.58e-16; mean CPM = 21.55; signal transducer and activator of transcription 5A" ID="ID_1535997823" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB3: 4.82-fold Down; FDR = 1.82e-12; PValue = 3.09e-14; mean CPM = 9.911; transforming growth factor, beta 3" ID="ID_1874538772" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3L2: 2.11-fold Down; FDR = 5.05e-12; PValue = 9.78e-14; mean CPM = 64.33; cAMP responsive element binding protein 3-like 2" ID="ID_393885547" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC4: 1.85-fold Down; FDR = 1.13e-11; PValue = 2.37e-13; mean CPM = 51.58; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4" ID="ID_1258562558" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_724810833" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3L1: 1.99-fold Down; FDR = 1.52e-09; PValue = 5.36e-11; mean CPM = 211.4; cAMP responsive element binding protein 3-like 1" ID="ID_356148168" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAVS: 1.92-fold Down; FDR = 2.7e-09; PValue = 1.02e-10; mean CPM = 29.16; mitochondrial antiviral signaling protein" ID="ID_1050590652" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR4: 3.45-fold Up; FDR = 3.1e-09; PValue = 1.19e-10; mean CPM = 7.456; Macaca mulatta toll-like receptor 4 (TLR4), mRNA." ID="ID_972198946" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1B: 1.64-fold Up; FDR = 1.22e-08; PValue = 5.39e-10; mean CPM = 32.96; Cyclin-dependent kinase inhibitor 1B; Uncharacterized protein" ID="ID_599793512" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP6AP1: 1.65-fold Down; FDR = 1.8e-08; PValue = 8.33e-10; mean CPM = 82.41; ATPase, H+ transporting, lysosomal accessory protein 1" ID="ID_137528476" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_266311604" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RB1: 1.65-fold Up; FDR = 6.01e-08; PValue = 3.2e-09; mean CPM = 59.24; retinoblastoma 1" ID="ID_1804704968" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2B: 3.54-fold Up; FDR = 1.24e-07; PValue = 7.07e-09; mean CPM = 5.971; PTK2B protein tyrosine kinase 2 beta" ID="ID_27552666" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_59249935" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_587865186" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_271469078" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_197751926" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_733805152" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_1192451619" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_485031972" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT4: 1.79-fold Up; FDR = 2.3e-05; PValue = 2.36e-06; mean CPM = 26.79; signal transducer and activator of transcription 4" ID="ID_354504750" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VDAC3: 1.37-fold Up; FDR = 8.35e-05; PValue = 1.01e-05; mean CPM = 104.8; voltage-dependent anion channel 3" ID="ID_1886749300" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB5: 2.1-fold Down; FDR = 0.000248; PValue = 3.48e-05; mean CPM = 4.269; cAMP responsive element binding protein 5" ID="ID_1687076035" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC2: 4.03-fold Down; FDR = 0.000346; PValue = 5.06e-05; mean CPM = 1.347; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2" ID="ID_1684211549" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF2: 1.34-fold Up; FDR = 0.000403; PValue = 6.01e-05; mean CPM = 39.83; activating transcription factor 2" ID="ID_1029690327" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_171472591" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD3: 1.38-fold Up; FDR = 0.000573; PValue = 8.94e-05; mean CPM = 114.9; SMAD family member 3" ID="ID_1803584094" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAD: 1.36-fold Down; FDR = 0.000605; PValue = 9.52e-05; mean CPM = 48.46; BCL2-associated agonist of cell death" ID="ID_101685022" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGR2: 1.8-fold Down; FDR = 0.00121; PValue = 0.000209; mean CPM = 15.95; early growth response 2" ID="ID_1979714672" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP9: 4.49-fold Down; FDR = 0.00222; PValue = 0.000419; mean CPM = 6.597; matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)" ID="ID_1403727530" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF4: 1.29-fold Up; FDR = 0.00296; PValue = 0.000579; mean CPM = 618.7; activating transcription factor 4 (tax-responsive enhancer element B67)" ID="ID_197482178" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBK1: 1.3-fold Up; FDR = 0.00337; PValue = 0.000674; mean CPM = 30.46; TANK-binding kinase 1" ID="ID_966865559" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PCNA: 1.34-fold Up; FDR = 0.00398; PValue = 0.000816; mean CPM = 112.1; PCNA antisense RNA (non-protein coding)" ID="ID_638660644" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1330520272" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_616092457" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR1: 1.27-fold Up; FDR = 0.0101; PValue = 0.00237; mean CPM = 82.39; Uncharacterized protein" ID="ID_1247875175" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HBXIP: 1.24-fold Up; FDR = 0.0155; PValue = 0.00392; mean CPM = 74.39; Uncharacterized protein" ID="ID_221656500" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP10: 1.81-fold Up; FDR = 0.0175; PValue = 0.0045; mean CPM = 2.876; caspase 10, apoptosis-related cysteine peptidase" ID="ID_554454686" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK2: 1.23-fold Down; FDR = 0.0194; PValue = 0.00507; mean CPM = 36.76; cyclin-dependent kinase 2" ID="ID_1859936562" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1194693343" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL8: 2.33-fold Up; FDR = 0.0209; PValue = 0.00552; mean CPM = 2326; interleukin 8" ID="ID_1574831957" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1441858612" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_317874045" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB1: 1.21-fold Up; FDR = 0.0313; PValue = 0.00884; mean CPM = 36.07; cAMP responsive element binding protein 1" ID="ID_538803426" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGR3: 2.19-fold Down; FDR = 0.0355; PValue = 0.0103; mean CPM = 3.291; early growth response 3" ID="ID_1173351675" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFBR1: 1.2-fold Up; FDR = 0.037; PValue = 0.0108; mean CPM = 90.92; transforming growth factor, beta receptor 1" ID="ID_1824421243" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1766630215" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KRAS: 1.35-fold Down; FDR = 0.0401; PValue = 0.0119; mean CPM = 13.10; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog" ID="ID_1640795825" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="E2F1: 1.44-fold Down; FDR = 0.0425; PValue = 0.0127; mean CPM = 8.857; E2F transcription factor 1" ID="ID_1860676948" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NRAS: 1.2-fold Down; FDR = 0.0546; PValue = 0.017; mean CPM = 32.39; neuroblastoma RAS viral (v-ras) oncogene homolog" ID="ID_341983983" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_914756554" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_530807889" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT6: 1.18-fold Up; FDR = 0.0727; PValue = 0.024; mean CPM = 217.5; signal transducer and activator of transcription 6, interleukin-4 induced" ID="ID_1139901753" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FADD: 1.18-fold Down; FDR = 0.0936; PValue = 0.0324; mean CPM = 30.89; Uncharacterized protein" ID="ID_1446887368" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_1601648351" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3L4: 1.3-fold Down; FDR = 0.0961; PValue = 0.0334; mean CPM = 6.034; cAMP responsive element binding protein 3-like 4" ID="ID_1204299087" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_1220885310" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3: 1.15-fold Up; FDR = 0.128; PValue = 0.0472; mean CPM = 167.9; cAMP responsive element binding protein 3" ID="ID_1990571178" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_72496514" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC5: 1.51-fold Down; FDR = 0.134; PValue = 0.0501; mean CPM = 18.55; Baculoviral IAP repeat-containing protein 5 isoform 1; Uncharacterized protein" ID="ID_1355115867" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1533382388" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTEN: 1.14-fold Up; FDR = 0.166; PValue = 0.065; mean CPM = 89.60; phosphatase and tensin homolog" ID="ID_1576742593" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1453129759" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000039103: 1.67-fold Down; FDR = 0.221; PValue = 0.0927; mean CPM = 1.310; Uncharacterized protein" ID="ID_1320547794" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1A: 1.16-fold Down; FDR = 0.28; PValue = 0.124; mean CPM = 363.2; Cyclin-dependent kinase inhibitor 1; Uncharacterized protein" ID="ID_271773782" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_693546736" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK6: 1.18-fold Down; FDR = 0.301; PValue = 0.136; mean CPM = 26.51; cyclin-dependent kinase 6" ID="ID_674044307" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EP300: 1.11-fold Up; FDR = 0.312; PValue = 0.142; mean CPM = 162.8; E1A binding protein p300" ID="ID_467418572" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_1416260400" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP53: 1.11-fold Down; FDR = 0.364; PValue = 0.172; mean CPM = 33.25; tumor protein p53" ID="ID_785382831" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1778837856" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2: 1.48-fold Up; FDR = 0.384; PValue = 0.184; mean CPM = 1.344; Uncharacterized protein" ID="ID_1364728875" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TICAM1: 1.11-fold Down; FDR = 0.398; PValue = 0.192; mean CPM = 26.73; toll-like receptor adaptor molecule 1" ID="ID_1187104263" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1822078636" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC1: 1.11-fold Down; FDR = 0.457; PValue = 0.23; mean CPM = 19.06; Uncharacterized protein" ID="ID_847635851" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DDX3X: 1.09-fold Up; FDR = 0.478; PValue = 0.244; mean CPM = 344.2; DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked" ID="ID_1932149855" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_19370890" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCG: 1.47-fold Down; FDR = 0.609; PValue = 0.336; mean CPM = 0.9297; protein kinase C, gamma" ID="ID_90705621" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCB: 1.86-fold Up; FDR = 0.727; PValue = 0.43; mean CPM = 0.8705; protein kinase C, beta" ID="ID_1448886862" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNB1: 1.79-fold Up; FDR = 0.731; PValue = 0.433; mean CPM = 0.8526; interferon, beta 1, fibroblast" ID="ID_222349689" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="E2F3: 1.08-fold Up; FDR = 0.751; PValue = 0.452; mean CPM = 11.79; E2F transcription factor 3" ID="ID_89028469" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_1935470544" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREBL1: 1.05-fold Down; FDR = 0.794; PValue = 0.491; mean CPM = 64.18; activating transcription factor 6 beta" ID="ID_66101559" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA6: 1.41-fold Down; FDR = 0.807; PValue = 0.504; mean CPM = 0.8019; interferon, alpha 6" ID="ID_1310021666" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAX: 1.05-fold Up; FDR = 0.809; PValue = 0.506; mean CPM = 162.4; Uncharacterized protein" ID="ID_1948843499" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APAF1: 1.05-fold Down; FDR = 0.837; PValue = 0.543; mean CPM = 32.11; apoptotic peptidase activating factor 1" ID="ID_274424821" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TIRAP: 1.07-fold Up; FDR = 0.841; PValue = 0.548; mean CPM = 8.693; Macaca mulatta toll-interleukin 1 receptor (TIR) domain containing adaptor protein (TIRAP), mRNA." ID="ID_1834957854" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYCS: 1.05-fold Up; FDR = 0.854; PValue = 0.565; mean CPM = 93.43; cytochrome c, somatic" ID="ID_127943866" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_158203140" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000040219: 1.08-fold Up; FDR = 0.86; PValue = 0.575; mean CPM = 8.818; Uncharacterized protein" ID="ID_851308765" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1822727298" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_1258501241" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK4: 1.04-fold Up; FDR = 0.899; PValue = 0.626; mean CPM = 65.45; cyclin-dependent kinase 4" ID="ID_7513619" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB2: 1.05-fold Down; FDR = 0.903; PValue = 0.655; mean CPM = 110.8; transforming growth factor, beta 2" ID="ID_1924789942" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD4: 1.03-fold Down; FDR = 0.906; PValue = 0.666; mean CPM = 43.02; SMAD family member 4" ID="ID_1998119688" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA13: 1.13-fold Up; FDR = 0.908; PValue = 0.677; mean CPM = 0.7960; interferon, alpha 13" ID="ID_1798209928" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3L3: 1.4-fold Down; FDR = 0.908; PValue = 0.679; mean CPM = 0.8407; cAMP responsive element binding protein 3-like 3" ID="ID_1562687748" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA8: 1.13-fold Down; FDR = 0.911; PValue = 0.702; mean CPM = 0.7910; interferon, alpha 8" ID="ID_45642437" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKE: 1.03-fold Up; FDR = 0.929; PValue = 0.737; mean CPM = 21.61; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon" ID="ID_983601010" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB1: 1.02-fold Down; FDR = 0.936; PValue = 0.749; mean CPM = 62.61; transforming growth factor, beta 1" ID="ID_1228538967" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FASLG: 1.2-fold Down; FDR = 0.941; PValue = 0.757; mean CPM = 0.8088; Fas ligand (TNF superfamily, member 6)" ID="ID_1484971446" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_1682180505" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC3: 1.03-fold Down; FDR = 0.952; PValue = 0.78; mean CPM = 13.31; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3" ID="ID_1860081339" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000009289: 1.07-fold Up; FDR = 0.963; PValue = 0.798; mean CPM = 2.536; Uncharacterized protein" ID="ID_57627969" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA14: 1.22-fold Up; FDR = 0.965; PValue = 0.802; mean CPM = 0.8654; interferon, alpha 14" ID="ID_384029002" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA4: 1.28-fold Down; FDR = 0.983; PValue = 0.829; mean CPM = 0.8584; interferon, alpha 4" ID="ID_1064913429" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREBBP: 1.01-fold Down; FDR = 0.993; PValue = 0.847; mean CPM = 137.7; CREB binding protein" ID="ID_1944631845" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="E2F2: 1.03-fold Up; FDR = 1; PValue = 0.906; mean CPM = 1.976; E2F transcription factor 2" ID="ID_1561676133" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP9: 1.01-fold Up; FDR = 1; PValue = 0.908; mean CPM = 19.86; caspase 9, apoptosis-related cysteine peptidase" ID="ID_713126027" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA1: No Change; FDR = 1; PValue = 0.998; mean CPM = 0.8014; interferon, alpha 1" ID="ID_584524678" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg TNF signaling pathway: Upregulated, FDR = 0.336, PValue = 0.0379" ID="ID_432680532" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="MLKL: 8.31-fold Up; FDR = 6.73e-21; PValue = 2.09e-23; mean CPM = 34.78; mixed lineage kinase domain-like" ID="ID_1412842033" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_1738596634" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK3: 3.47-fold Up; FDR = 2.3e-12; PValue = 4.07e-14; mean CPM = 12.05; receptor-interacting serine-threonine kinase 3" ID="ID_786929277" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3L2: 2.11-fold Down; FDR = 5.05e-12; PValue = 9.78e-14; mean CPM = 64.33; cAMP responsive element binding protein 3-like 2" ID="ID_1219392729" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC2: 1.96-fold Up; FDR = 1.01e-10; PValue = 2.62e-12; mean CPM = 53.58; baculoviral IAP repeat-containing 2" ID="ID_249689048" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CFLAR: 1.87-fold Up; FDR = 5.09e-10; PValue = 1.61e-11; mean CPM = 103.3; CASP8 and FADD-like apoptosis regulator" ID="ID_104777636" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3L1: 1.99-fold Down; FDR = 1.52e-09; PValue = 5.36e-11; mean CPM = 211.4; cAMP responsive element binding protein 3-like 1" ID="ID_964377099" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_1889966617" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1580771815" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_1467341171" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_824876583" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_18348934" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_1147909408" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC3: 2.79-fold Up; FDR = 1.74e-06; PValue = 1.32e-07; mean CPM = 95.34; baculoviral IAP repeat-containing 3" ID="ID_464605998" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_326453711" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1B: 2.24-fold Up; FDR = 2.68e-06; PValue = 2.16e-07; mean CPM = 19.44; tumor necrosis factor receptor superfamily, member 1B" ID="ID_409749838" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K3: 1.45-fold Down; FDR = 7.01e-06; PValue = 6.34e-07; mean CPM = 180.1; mitogen-activated protein kinase kinase 3" ID="ID_487412839" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA5: 3.28-fold Up; FDR = 1.4e-05; PValue = 1.36e-06; mean CPM = 2.288; ribosomal protein S6 kinase, 90kDa, polypeptide 5" ID="ID_1653562604" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_151065008" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB5: 2.1-fold Down; FDR = 0.000248; PValue = 3.48e-05; mean CPM = 4.269; cAMP responsive element binding protein 5" ID="ID_365297345" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF2: 1.34-fold Up; FDR = 0.000403; PValue = 6.01e-05; mean CPM = 39.83; activating transcription factor 2" ID="ID_1860667667" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAG4: 1.32-fold Up; FDR = 0.00191; PValue = 0.000353; mean CPM = 25.62; BCL2-associated athanogene 4" ID="ID_1778745601" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF4: 1.29-fold Up; FDR = 0.00296; PValue = 0.000579; mean CPM = 618.7; activating transcription factor 4 (tax-responsive enhancer element B67)" ID="ID_32819585" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1837576554" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_394073880" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K14: 1.47-fold Down; FDR = 0.00704; PValue = 0.00157; mean CPM = 9.470; mitogen-activated protein kinase kinase kinase 14" ID="ID_1460122852" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP10: 1.81-fold Up; FDR = 0.0175; PValue = 0.0045; mean CPM = 2.876; caspase 10, apoptosis-related cysteine peptidase" ID="ID_1043925364" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PXMP2: 1.24-fold Down; FDR = 0.019; PValue = 0.00496; mean CPM = 27.63; phosphoglycerate mutase family member 5" ID="ID_1215158162" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1220746687" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DNM1L: 1.21-fold Up; FDR = 0.0244; PValue = 0.00662; mean CPM = 91.13; dynamin 1-like" ID="ID_1667012831" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_458966967" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB1: 1.21-fold Up; FDR = 0.0313; PValue = 0.00884; mean CPM = 36.07; cAMP responsive element binding protein 1" ID="ID_1980264604" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRADD: 1.22-fold Up; FDR = 0.0319; PValue = 0.00907; mean CPM = 34.75; TNFRSF1A-associated via death domain" ID="ID_1392878076" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1204422915" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K8: 1.35-fold Down; FDR = 0.0831; PValue = 0.0281; mean CPM = 8.912; mitogen-activated protein kinase kinase kinase 8" ID="ID_1467074583" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FADD: 1.18-fold Down; FDR = 0.0936; PValue = 0.0324; mean CPM = 30.89; Uncharacterized protein" ID="ID_375822590" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3L4: 1.3-fold Down; FDR = 0.0961; PValue = 0.0334; mean CPM = 6.034; cAMP responsive element binding protein 3-like 4" ID="ID_1082207195" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_17404588" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3: 1.15-fold Up; FDR = 0.128; PValue = 0.0472; mean CPM = 167.9; cAMP responsive element binding protein 3" ID="ID_369337279" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_179610588" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_966494489" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP7: 1.15-fold Up; FDR = 0.218; PValue = 0.0916; mean CPM = 21.49; caspase 7, apoptosis-related cysteine peptidase" ID="ID_1968863405" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_1370114847" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA4: 1.12-fold Down; FDR = 0.296; PValue = 0.133; mean CPM = 39.50; ribosomal protein S6 kinase, 90kDa, polypeptide 4" ID="ID_705229891" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1A: 1.11-fold Up; FDR = 0.297; PValue = 0.134; mean CPM = 134.7; tumor necrosis factor receptor superfamily, member 1A" ID="ID_200599247" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_1610059799" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_936772584" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_1125871614" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_598447177" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK12: 1.19-fold Down; FDR = 0.422; PValue = 0.208; mean CPM = 6.569; mitogen-activated protein kinase 12" ID="ID_160554923" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1106576691" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_1619723801" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK13: 1.22-fold Down; FDR = 0.536; PValue = 0.284; mean CPM = 3.100; mitogen-activated protein kinase 13" ID="ID_1480581365" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K5: 1.21-fold Down; FDR = 0.6; PValue = 0.33; mean CPM = 8.023; mitogen-activated protein kinase kinase kinase 5" ID="ID_903187418" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_139785153" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREBL1: 1.05-fold Down; FDR = 0.794; PValue = 0.491; mean CPM = 64.18; activating transcription factor 6 beta" ID="ID_1901781744" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_984262519" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_1955412340" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAGI2: 1.06-fold Down; FDR = 0.903; PValue = 0.655; mean CPM = 7.972; Uncharacterized protein" ID="ID_1737504729" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3L3: 1.4-fold Down; FDR = 0.908; PValue = 0.679; mean CPM = 0.8407; cAMP responsive element binding protein 3-like 3" ID="ID_567324917" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_156764766" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_1039514872" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Toll-like receptor signaling pathway: Upregulated, FDR = 0.336, PValue = 0.0394" ID="ID_1612870368" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TLR2: 8.94-fold Up; FDR = 6.97e-23; PValue = 1.25e-25; mean CPM = 18.41; toll-like receptor 2" ID="ID_778972265" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL10: 462-fold Up; FDR = 1.01e-21; PValue = 2.65e-24; mean CPM = 286.2; Macaca mulatta chemokine (C-X-C motif) ligand 10 (CXCL10), mRNA." ID="ID_1627310153" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR3: 10.3-fold Up; FDR = 1.95e-21; PValue = 5.6e-24; mean CPM = 35.70; toll-like receptor 3" ID="ID_1326743868" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL11: 256-fold Up; FDR = 1e-19; PValue = 3.96e-22; mean CPM = 84.82; chemokine (C-X-C motif) ligand 11" ID="ID_694159482" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL9: 345-fold Up; FDR = 4.16e-19; PValue = 1.97e-21; mean CPM = 175.7; Macaca mulatta chemokine (C-X-C motif) ligand 9 (CXCL9), mRNA." ID="ID_755653112" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1000151187" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF7: 14.8-fold Up; FDR = 7.66e-18; PValue = 4.82e-20; mean CPM = 11.54; Macaca mulatta interferon regulatory factor 7 (IRF7), mRNA." ID="ID_741450231" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_285993811" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LY96: 3.13-fold Up; FDR = 1.27e-10; PValue = 3.43e-12; mean CPM = 6.127; lymphocyte antigen 96" ID="ID_669629714" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR4: 3.45-fold Up; FDR = 3.1e-09; PValue = 1.19e-10; mean CPM = 7.456; Macaca mulatta toll-like receptor 4 (TLR4), mRNA." ID="ID_1490156675" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_1173431451" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK4: 1.8-fold Up; FDR = 3.31e-08; PValue = 1.64e-09; mean CPM = 12.89; interleukin-1 receptor-associated kinase 4" ID="ID_1360472966" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1201059895" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL5: 6.74-fold Up; FDR = 2.65e-07; PValue = 1.64e-08; mean CPM = 30.35; chemokine (C-C motif) ligand 5" ID="ID_1350098742" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_152187562" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD14: 2.75-fold Down; FDR = 6.54e-07; PValue = 4.46e-08; mean CPM = 5.195; CD14 molecule" ID="ID_107514480" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_373434723" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_755722940" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR2: 1.74-fold Up; FDR = 1.85e-06; PValue = 1.44e-07; mean CPM = 26.05; interferon (alpha, beta and omega) receptor 2" ID="ID_1995138353" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_705706401" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K3: 1.45-fold Down; FDR = 7.01e-06; PValue = 6.34e-07; mean CPM = 180.1; mitogen-activated protein kinase kinase 3" ID="ID_1779453280" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_346426853" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPP1: 2.25-fold Down; FDR = 7.74e-05; PValue = 9.29e-06; mean CPM = 35.33; secreted phosphoprotein 1" ID="ID_556488428" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP2: 1.45-fold Up; FDR = 0.000179; PValue = 2.4e-05; mean CPM = 65.31; TGF-beta activated kinase 1/MAP3K7 binding protein 2" ID="ID_1575545851" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40: 2.76-fold Up; FDR = 0.00039; PValue = 5.79e-05; mean CPM = 9.139; CD40 molecule, TNF receptor superfamily member 5" ID="ID_167891206" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TOLLIP: 1.36-fold Down; FDR = 0.000551; PValue = 8.57e-05; mean CPM = 28.79; Uncharacterized protein" ID="ID_1959180248" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBK1: 1.3-fold Up; FDR = 0.00337; PValue = 0.000674; mean CPM = 30.46; TANK-binding kinase 1" ID="ID_1730271134" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1869811516" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_799229612" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR5: 1.86-fold Down; FDR = 0.00878; PValue = 0.00203; mean CPM = 3.008; toll-like receptor 5" ID="ID_385530328" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12A: 2.09-fold Up; FDR = 0.00924; PValue = 0.00215; mean CPM = 2.872; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)" ID="ID_10663115" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR1: 1.27-fold Up; FDR = 0.0101; PValue = 0.00237; mean CPM = 82.39; Uncharacterized protein" ID="ID_698738529" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1743415315" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL8: 2.33-fold Up; FDR = 0.0209; PValue = 0.00552; mean CPM = 2326; interleukin 8" ID="ID_193352805" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1861044932" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_687517153" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1133638007" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL3: 2.04-fold Down; FDR = 0.067; PValue = 0.0218; mean CPM = 3.575; chemokine (C-C motif) ligand 3" ID="ID_128742732" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K8: 1.35-fold Down; FDR = 0.0831; PValue = 0.0281; mean CPM = 8.912; mitogen-activated protein kinase kinase kinase 8" ID="ID_985708871" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FADD: 1.18-fold Down; FDR = 0.0936; PValue = 0.0324; mean CPM = 30.89; Uncharacterized protein" ID="ID_205313401" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_1990253284" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_760435978" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1133392898" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_1424330014" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_1851384033" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP1: 1.12-fold Down; FDR = 0.351; PValue = 0.165; mean CPM = 17.96; TGF-beta activated kinase 1/MAP3K7 binding protein 1" ID="ID_826881481" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_239805936" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TICAM1: 1.11-fold Down; FDR = 0.398; PValue = 0.192; mean CPM = 26.73; toll-like receptor adaptor molecule 1" ID="ID_327901408" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_1032870234" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_308857257" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK12: 1.19-fold Down; FDR = 0.422; PValue = 0.208; mean CPM = 6.569; mitogen-activated protein kinase 12" ID="ID_373674050" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_306966622" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_435588091" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK13: 1.22-fold Down; FDR = 0.536; PValue = 0.284; mean CPM = 3.100; mitogen-activated protein kinase 13" ID="ID_1916537516" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF3: 1.07-fold Up; FDR = 0.611; PValue = 0.338; mean CPM = 34.56; TNF receptor-associated factor 3" ID="ID_1049022353" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_1830872729" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNB1: 1.79-fold Up; FDR = 0.731; PValue = 0.433; mean CPM = 0.8526; interferon, beta 1, fibroblast" ID="ID_1335936977" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA6: 1.41-fold Down; FDR = 0.807; PValue = 0.504; mean CPM = 0.8019; interferon, alpha 6" ID="ID_1350443304" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR6: 1.07-fold Down; FDR = 0.84; PValue = 0.546; mean CPM = 7.909; toll-like receptor 6" ID="ID_1482936070" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TIRAP: 1.07-fold Up; FDR = 0.841; PValue = 0.548; mean CPM = 8.693; Macaca mulatta toll-interleukin 1 receptor (TIR) domain containing adaptor protein (TIRAP), mRNA." ID="ID_550818769" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF5: 1.06-fold Down; FDR = 0.85; PValue = 0.561; mean CPM = 9.280; interferon regulatory factor 5" ID="ID_1479187137" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1809877665" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1712045081" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR7: 1.37-fold Down; FDR = 0.878; PValue = 0.597; mean CPM = 0.8402; toll-like receptor 7" ID="ID_671822925" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK1: 1.04-fold Down; FDR = 0.885; PValue = 0.606; mean CPM = 41.54; interleukin-1 receptor-associated kinase 1" ID="ID_673298012" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_1577281871" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA13: 1.13-fold Up; FDR = 0.908; PValue = 0.677; mean CPM = 0.7960; interferon, alpha 13" ID="ID_1560399762" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA8: 1.13-fold Down; FDR = 0.911; PValue = 0.702; mean CPM = 0.7910; interferon, alpha 8" ID="ID_1197252737" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKE: 1.03-fold Up; FDR = 0.929; PValue = 0.737; mean CPM = 21.61; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon" ID="ID_237656867" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA14: 1.22-fold Up; FDR = 0.965; PValue = 0.802; mean CPM = 0.8654; interferon, alpha 14" ID="ID_1475485554" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_1701472029" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD80: 1.08-fold Up; FDR = 0.971; PValue = 0.812; mean CPM = 1.157; CD80 molecule" ID="ID_1948169707" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_1005338883" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA4: 1.28-fold Down; FDR = 0.983; PValue = 0.829; mean CPM = 0.8584; interferon, alpha 4" ID="ID_1323000898" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12B: 1.07-fold Up; FDR = 0.983; PValue = 0.831; mean CPM = 0.8197; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)" ID="ID_1315345309" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_421259920" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR9: 1.01-fold Down; FDR = 1; PValue = 0.859; mean CPM = 21.45; Macaca mulatta toll-like receptor 9 (TLR9), mRNA." ID="ID_1573502065" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR1: 1.02-fold Up; FDR = 1; PValue = 0.945; mean CPM = 1.221; toll-like receptor 1" ID="ID_416692215" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD86: 1.01-fold Down; FDR = 1; PValue = 0.99; mean CPM = 0.8012; CD86 molecule" ID="ID_407664740" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA1: No Change; FDR = 1; PValue = 0.998; mean CPM = 0.8014; interferon, alpha 1" ID="ID_682462344" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Vasopressin-regulated water reabsorption: Downregulated, FDR = 0.336, PValue = 0.0396" ID="ID_925579338" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CREB3L2: 2.11-fold Down; FDR = 5.05e-12; PValue = 9.78e-14; mean CPM = 64.33; cAMP responsive element binding protein 3-like 2" ID="ID_405561968" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY6: 1.89-fold Down; FDR = 1.9e-10; PValue = 5.38e-12; mean CPM = 141.3; adenylate cyclase 6" ID="ID_1408057128" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3L1: 1.99-fold Down; FDR = 1.52e-09; PValue = 5.36e-11; mean CPM = 211.4; cAMP responsive element binding protein 3-like 1" ID="ID_1481047483" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARHGDIA: 1.49-fold Down; FDR = 3.61e-06; PValue = 3.01e-07; mean CPM = 257.2; Rho GDP dissociation inhibitor (GDI) alpha" ID="ID_479900196" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACA: 1.36-fold Down; FDR = 0.000167; PValue = 2.22e-05; mean CPM = 37.75; protein kinase, cAMP-dependent, catalytic, alpha" ID="ID_1872485768" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB5: 2.1-fold Down; FDR = 0.000248; PValue = 3.48e-05; mean CPM = 4.269; cAMP responsive element binding protein 5" ID="ID_1290175798" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STX4: 1.32-fold Up; FDR = 0.00111; PValue = 0.000191; mean CPM = 32.39; syntaxin 4" ID="ID_1398021676" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAS1: 1.31-fold Down; FDR = 0.00158; PValue = 0.000283; mean CPM = 564.9; Uncharacterized protein" ID="ID_405632976" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKX: 1.31-fold Down; FDR = 0.00331; PValue = 0.000658; mean CPM = 24.94; protein kinase, X-linked" ID="ID_1937199480" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY9: 1.32-fold Down; FDR = 0.00986; PValue = 0.00231; mean CPM = 84.04; adenylate cyclase 9" ID="ID_321399238" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB1: 1.21-fold Up; FDR = 0.0313; PValue = 0.00884; mean CPM = 36.07; cAMP responsive element binding protein 1" ID="ID_1344786652" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3L4: 1.3-fold Down; FDR = 0.0961; PValue = 0.0334; mean CPM = 6.034; cAMP responsive element binding protein 3-like 4" ID="ID_305462014" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARHGDIB: 2.5-fold Down; FDR = 0.124; PValue = 0.0456; mean CPM = 1.180; Rho GDP dissociation inhibitor (GDI) beta" ID="ID_1886108873" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3: 1.15-fold Up; FDR = 0.128; PValue = 0.0472; mean CPM = 167.9; cAMP responsive element binding protein 3" ID="ID_1484746601" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACG: 1.51-fold Down; FDR = 0.795; PValue = 0.491; mean CPM = 0.8026; protein kinase, cAMP-dependent, catalytic, gamma" ID="ID_358458716" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AQP2: 1.18-fold Down; FDR = 0.903; PValue = 0.661; mean CPM = 0.7909; aquaporin 2 (collecting duct)" ID="ID_1365114112" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000021684: 1.44-fold Up; FDR = 0.903; PValue = 0.662; mean CPM = 0.8513; Uncharacterized protein" ID="ID_1290691059" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB3L3: 1.4-fold Down; FDR = 0.908; PValue = 0.679; mean CPM = 0.8407; cAMP responsive element binding protein 3-like 3" ID="ID_97878687" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACB: 1.03-fold Up; FDR = 0.911; PValue = 0.694; mean CPM = 30.10; protein kinase, cAMP-dependent, catalytic, beta" ID="ID_1559777267" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY3: 1.01-fold Up; FDR = 1; PValue = 0.871; mean CPM = 34.92; adenylate cyclase 3" ID="ID_1096250535" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="graphite/kegg Leishmaniasis: Upregulated, FDR = 0.361, PValue = 0.0446" ID="ID_1465816965" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TLR2: 8.94-fold Up; FDR = 6.97e-23; PValue = 1.25e-25; mean CPM = 18.41; toll-like receptor 2" ID="ID_1698118247" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_604942410" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_34709590" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB3: 4.82-fold Down; FDR = 1.82e-12; PValue = 3.09e-14; mean CPM = 9.911; transforming growth factor, beta 3" ID="ID_274198699" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR4: 3.45-fold Up; FDR = 3.1e-09; PValue = 1.19e-10; mean CPM = 7.456; Macaca mulatta toll-like receptor 4 (TLR4), mRNA." ID="ID_406329196" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK4: 1.8-fold Up; FDR = 3.31e-08; PValue = 1.64e-09; mean CPM = 12.89; interleukin-1 receptor-associated kinase 4" ID="ID_1839486437" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1912808268" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP2: 1.45-fold Up; FDR = 0.000179; PValue = 2.4e-05; mean CPM = 65.31; TGF-beta activated kinase 1/MAP3K7 binding protein 2" ID="ID_960905476" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTGS2: 2.02-fold Up; FDR = 0.000254; PValue = 3.59e-05; mean CPM = 314.5; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)" ID="ID_1067319974" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYBA: 1.34-fold Up; FDR = 0.00107; PValue = 0.000183; mean CPM = 376.6; cytochrome b-245, alpha polypeptide" ID="ID_513147741" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR1: 1.31-fold Up; FDR = 0.00151; PValue = 0.000268; mean CPM = 37.77; interferon gamma receptor 1" ID="ID_326686253" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1007352566" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB2: 1.55-fold Down; FDR = 0.0187; PValue = 0.00485; mean CPM = 34.87; Integrin beta" ID="ID_524703581" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1817342177" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FCGR2B: 2.01-fold Up; FDR = 0.0231; PValue = 0.00623; mean CPM = 1.743; Uncharacterized protein" ID="ID_515784338" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR2: 1.23-fold Up; FDR = 0.0258; PValue = 0.00707; mean CPM = 46.52; interferon gamma receptor 2 (interferon gamma transducer 1)" ID="ID_1110181820" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1655314285" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_1090540383" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1503452870" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FCGR2A: 2.18-fold Up; FDR = 0.172; PValue = 0.0682; mean CPM = 0.9955; Fc fragment of IgG, low affinity IIa, receptor (CD32)" ID="ID_1986821480" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CR1: 1.99-fold Up; FDR = 0.225; PValue = 0.095; mean CPM = 0.9520; Uncharacterized protein" ID="ID_1278149548" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FCGR3A: 1.84-fold Down; FDR = 0.245; PValue = 0.106; mean CPM = 1.030; Fc fragment of IgG, low affinity IIIa, receptor (CD16a)" ID="ID_1710220877" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP1: 1.12-fold Down; FDR = 0.351; PValue = 0.165; mean CPM = 17.96; TGF-beta activated kinase 1/MAP3K7 binding protein 1" ID="ID_1836103382" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_455240557" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1389207406" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK12: 1.19-fold Down; FDR = 0.422; PValue = 0.208; mean CPM = 6.569; mitogen-activated protein kinase 12" ID="ID_1492273744" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_313085649" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCF2: 1.29-fold Up; FDR = 0.525; PValue = 0.276; mean CPM = 2.178; Uncharacterized protein" ID="ID_223832871" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK13: 1.22-fold Down; FDR = 0.536; PValue = 0.284; mean CPM = 3.100; mitogen-activated protein kinase 13" ID="ID_1827673770" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCF4: 1.16-fold Up; FDR = 0.69; PValue = 0.399; mean CPM = 6.357; neutrophil cytosolic factor 4, 40kDa" ID="ID_90310634" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCB: 1.86-fold Up; FDR = 0.727; PValue = 0.43; mean CPM = 0.8705; protein kinase C, beta" ID="ID_1684607574" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAM: 1.44-fold Down; FDR = 0.73; PValue = 0.432; mean CPM = 0.9052; integrin, alpha M (complement component 3 receptor 3 subunit)" ID="ID_1262555829" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK1: 1.04-fold Down; FDR = 0.885; PValue = 0.606; mean CPM = 41.54; interleukin-1 receptor-associated kinase 1" ID="ID_510302222" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_1575056913" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB2: 1.05-fold Down; FDR = 0.903; PValue = 0.655; mean CPM = 110.8; transforming growth factor, beta 2" ID="ID_7912430" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOS2: 1.4-fold Down; FDR = 0.917; PValue = 0.718; mean CPM = 0.8546; nitric oxide synthase 2, inducible" ID="ID_1520063923" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL4: 1.27-fold Down; FDR = 0.933; PValue = 0.745; mean CPM = 0.8077; interleukin 4" ID="ID_177590141" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB1: 1.02-fold Down; FDR = 0.936; PValue = 0.749; mean CPM = 62.61; transforming growth factor, beta 1" ID="ID_865291513" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_721711454" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000005832: 1.08-fold Up; FDR = 0.982; PValue = 0.828; mean CPM = 1.034; Uncharacterized protein" ID="ID_1267292074" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_1209457643" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL10: 1.21-fold Down; FDR = 1; PValue = 0.964; mean CPM = 0.8614; interleukin 10" ID="ID_307221444" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- </node>
- </node>
- </node>
- <node TEXT="ImmuneMap gene set collection" POSITION="right" ID="ID_1873360858" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CAMERA gene set test" ID="ID_1628620472" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="IFN alpha/beta: Upregulated, FDR = 0.00218, PValue = 5.76e-05" ID="ID_1602463471" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TAP1: 8.86-fold Up; FDR = 4.25e-27; PValue = 3.99e-31; mean CPM = 524.4; Antigen peptide transporter 1 (APT1)(Peptide transporter TAP1)(ATP-binding cassette sub-family B member 2)(Peptide supply factor 1)(Peptide transporter PSF1)(PSF-1)(Peptide transporter involved in antigen processing 1)(Really interesting new gene 4 /.../n)" ID="ID_1041034006" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMB8: 15.4-fold Up; FDR = 1.64e-26; PValue = 5.69e-30; mean CPM = 246.0; proteasome subunit beta type-8 isoform E1 proprotein" ID="ID_1834223421" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFITM1: 22.3-fold Up; FDR = 1.43e-23; PValue = 2.15e-26; mean CPM = 454.0; interferon induced transmembrane protein 1" ID="ID_989192510" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFIH1: 14.7-fold Up; FDR = 8.74e-23; PValue = 1.68e-25; mean CPM = 49.84; interferon induced with helicase C domain 1" ID="ID_810877379" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF1: 18.6-fold Up; FDR = 1.53e-21; PValue = 4.24e-24; mean CPM = 240.7; interferon regulatory factor 1" ID="ID_1994115218" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="OAS1: 41-fold Up; FDR = 1.01e-20; PValue = 3.28e-23; mean CPM = 37.38; Macaca mulatta 2',5'-oligoadenylate synthetase 1, 40/46kDa (OAS1), mRNA." ID="ID_925425766" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFIT1: 52.1-fold Up; FDR = 1.76e-20; PValue = 6.3e-23; mean CPM = 46.34; interferon-induced protein with tetratricopeptide repeats 1" ID="ID_1995712200" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFIT3: 63.7-fold Up; FDR = 7.87e-20; PValue = 3e-22; mean CPM = 372.5; interferon-induced protein with tetratricopeptide repeats 3" ID="ID_1640417247" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MX1: 48.9-fold Up; FDR = 9.52e-20; PValue = 3.71e-22; mean CPM = 84.25; myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)" ID="ID_1137491715" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF9: 3.85-fold Up; FDR = 2.6e-19; PValue = 1.12e-21; mean CPM = 106.4; interferon regulatory factor 9" ID="ID_1352270749" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT2: 2.67-fold Up; FDR = 8.02e-19; PValue = 4.03e-21; mean CPM = 185.6; signal transducer and activator of transcription 2, 113kDa" ID="ID_1107965597" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_1784596741" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1573963157" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ISG15: 15.5-fold Up; FDR = 2.16e-15; PValue = 2.02e-17; mean CPM = 55.60; ISG15 ubiquitin-like modifier" ID="ID_1573158721" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN2: 1.87-fold Up; FDR = 6.19e-10; PValue = 2e-11; mean CPM = 32.46; protein tyrosine phosphatase, non-receptor type 2" ID="ID_399977429" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_221229479" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR2: 1.74-fold Up; FDR = 1.85e-06; PValue = 1.44e-07; mean CPM = 26.05; interferon (alpha, beta and omega) receptor 2" ID="ID_686272680" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR1: 1.31-fold Up; FDR = 0.00151; PValue = 0.000268; mean CPM = 37.77; interferon gamma receptor 1" ID="ID_819732740" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIAS1: 1.3-fold Up; FDR = 0.00259; PValue = 0.000498; mean CPM = 29.99; protein inhibitor of activated STAT, 1" ID="ID_609688466" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL18: 1.5-fold Down; FDR = 0.00981; PValue = 0.0023; mean CPM = 6.489; interleukin 18 (interferon-gamma-inducing factor)" ID="ID_1200222558" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR1: 1.27-fold Up; FDR = 0.0101; PValue = 0.00237; mean CPM = 82.39; Uncharacterized protein" ID="ID_1897274290" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYK2: 1.24-fold Down; FDR = 0.0142; PValue = 0.00354; mean CPM = 42.58; tyrosine kinase 2" ID="ID_863262925" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR2: 1.23-fold Up; FDR = 0.0258; PValue = 0.00707; mean CPM = 46.52; interferon gamma receptor 2 (interferon gamma transducer 1)" ID="ID_799043108" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_1442243454" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2: 1.48-fold Up; FDR = 0.384; PValue = 0.184; mean CPM = 1.344; Uncharacterized protein" ID="ID_1752031755" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016250: 1.52-fold Up; FDR = 0.419; PValue = 0.205; mean CPM = 1.143" ID="ID_1651907982" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNB1: 1.79-fold Up; FDR = 0.731; PValue = 0.433; mean CPM = 0.8526; interferon, beta 1, fibroblast" ID="ID_237476617" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFITM1: 1.63-fold Up; FDR = 0.767; PValue = 0.465; mean CPM = 0.8148; interferon induced transmembrane protein 1 (9-27)" ID="ID_1216187246" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAX: 1.05-fold Up; FDR = 0.809; PValue = 0.506; mean CPM = 162.4; Uncharacterized protein" ID="ID_427600441" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_1837965998" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000028965: 1.11-fold Up; FDR = 0.911; PValue = 0.697; mean CPM = 1.501; Uncharacterized protein" ID="ID_1245528926" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MED14: 1.01-fold Down; FDR = 1; PValue = 0.916; mean CPM = 56.17; mediator complex subunit 14" ID="ID_1993520366" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA1: No Change; FDR = 1; PValue = 0.998; mean CPM = 0.8014; interferon, alpha 1" ID="ID_491687490" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Antigen processing and presentation: Upregulated, FDR = 0.00218, PValue = 8.08e-05" ID="ID_1869860883" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TAP1: 8.86-fold Up; FDR = 4.25e-27; PValue = 3.99e-31; mean CPM = 524.4; Antigen peptide transporter 1 (APT1)(Peptide transporter TAP1)(ATP-binding cassette sub-family B member 2)(Peptide supply factor 1)(Peptide transporter PSF1)(PSF-1)(Peptide transporter involved in antigen processing 1)(Really interesting new gene 4 /.../n)" ID="ID_1041510020" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014803: 6.92-fold Up; FDR = 4.41e-27; PValue = 6.21e-31; mean CPM = 361.1; Uncharacterized protein" ID="ID_1000828285" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTSS: 17.2-fold Up; FDR = 6.21e-25; PValue = 3.79e-28; mean CPM = 42.75; cathepsin S" ID="ID_492379828" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSME1: 5.25-fold Up; FDR = 7.8e-24; PValue = 9.53e-27; mean CPM = 157.6; Uncharacterized protein" ID="ID_188615030" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFI30: 14.5-fold Up; FDR = 1.96e-22; PValue = 4.32e-25; mean CPM = 117.9; interferon, gamma-inducible protein 30" ID="ID_996887937" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000027180: 6.97-fold Up; FDR = 1.24e-21; PValue = 3.39e-24; mean CPM = 285.4; Uncharacterized protein" ID="ID_488604981" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000027180: 6.97-fold Up; FDR = 1.24e-21; PValue = 3.39e-24; mean CPM = 285.4; Uncharacterized protein" ID="ID_1760601695" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000005183: 4.07-fold Up; FDR = 2.87e-21; PValue = 8.51e-24; mean CPM = 164.7; Uncharacterized protein" ID="ID_801587617" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000005183: 4.07-fold Up; FDR = 2.87e-21; PValue = 8.51e-24; mean CPM = 164.7; Uncharacterized protein" ID="ID_573322979" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-B: 6.07-fold Up; FDR = 2.71e-19; PValue = 1.2e-21; mean CPM = 2098; Uncharacterized protein" ID="ID_1789697516" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CIITA: 45.8-fold Up; FDR = 1.14e-17; PValue = 7.44e-20; mean CPM = 27.80; class II, major histocompatibility complex, transactivator" ID="ID_1359882028" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD74: 104-fold Up; FDR = 6e-17; PValue = 4.54e-19; mean CPM = 141.5; CD74 molecule, major histocompatibility complex, class II invariant chain" ID="ID_813102029" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DMB: 17.5-fold Up; FDR = 2.77e-15; PValue = 2.66e-17; mean CPM = 9.464; HLA class II histocompatibility antigen, DM beta chain Precursor (MHC class II antigen DMB)(Really interesting new gene 7 protein)" ID="ID_1105368515" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DPA1: 107-fold Up; FDR = 5.97e-15; PValue = 6.11e-17; mean CPM = 17.08; HLA class II histocompatibility antigen, DP alpha 1 chain Precursor (HLA-SB alpha chain)(MHC class II DP3-alpha)(DP(W3))(DP(W4))" ID="ID_1828735676" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA2: 4.21-fold Down; FDR = 2.4e-14; PValue = 2.77e-16; mean CPM = 66.42; heat shock 70kDa protein 2" ID="ID_1757322897" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DQB1: 31.1-fold Up; FDR = 6.93e-13; PValue = 1.1e-14; mean CPM = 6.675; Macaca mulatta MHC class II antigen (MAMU-DRB), mRNA." ID="ID_557265970" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA1B: 2.24-fold Down; FDR = 4.33e-09; PValue = 1.71e-10; mean CPM = 44.90; Heat shock 70 kDa protein 1A/1B (Heat shock 70 kDa protein 1/2)(HSP70.1/HSP70.2)(HSP70-1/HSP70-2)" ID="ID_1925951631" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALR: 1.71-fold Down; FDR = 1.22e-08; PValue = 5.36e-10; mean CPM = 674.0; calreticulin" ID="ID_1485102879" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA8: 1.64-fold Up; FDR = 1.46e-08; PValue = 6.6e-10; mean CPM = 1881; heat shock 70kDa protein 8" ID="ID_1865383724" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA1: 15.1-fold Up; FDR = 1.9e-08; PValue = 8.86e-10; mean CPM = 3.665; HLA class II histocompatibility antigen, DQ alpha 1 chain precursor" ID="ID_1513642466" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DPB1: 7.73-fold Up; FDR = 4.73e-08; PValue = 2.45e-09; mean CPM = 1.528; Macaca mulatta major histocompatibility complex, class II, DP beta (MAMU-DPB), mRNA." ID="ID_622419608" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTSL1: 1.84-fold Up; FDR = 6.74e-08; PValue = 3.62e-09; mean CPM = 326.4; cathepsin L1" ID="ID_1112133007" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RFX5: 1.45-fold Up; FDR = 2.02e-06; PValue = 1.58e-07; mean CPM = 51.69; regulatory factor X, 5 (influences HLA class II expression)" ID="ID_861453235" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90AA1: 1.41-fold Up; FDR = 4.17e-05; PValue = 4.62e-06; mean CPM = 609.6; heat shock protein 90kDa alpha (cytosolic), class A member 2" ID="ID_19598559" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA6: 2.05-fold Down; FDR = 0.0226; PValue = 0.00604; mean CPM = 2.573; heat shock 70kDa protein 6 (HSP70B')" ID="ID_1307357303" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB1: 1.21-fold Up; FDR = 0.0313; PValue = 0.00884; mean CPM = 36.07; cAMP responsive element binding protein 1" ID="ID_1842879421" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DOA: 2.74-fold Up; FDR = 0.0694; PValue = 0.0227; mean CPM = 0.9089; HLA class II histocompatibility antigen, DO alpha chain Precursor (MHC class II antigen DOA)(MHC DZ alpha)(MHC DN-alpha)" ID="ID_668510298" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDIA3: 1.17-fold Up; FDR = 0.11; PValue = 0.0393; mean CPM = 521.1; protein disulfide isomerase family A, member 3" ID="ID_1946181288" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RFXANK: 1.15-fold Up; FDR = 0.166; PValue = 0.0651; mean CPM = 33.20; regulatory factor X-associated ankyrin-containing protein" ID="ID_812545406" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFYA: 1.14-fold Up; FDR = 0.174; PValue = 0.069; mean CPM = 34.54; nuclear transcription factor Y, alpha" ID="ID_1683547180" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014796: 1.77-fold Up; FDR = 0.381; PValue = 0.182; mean CPM = 0.9085; Uncharacterized protein" ID="ID_909592956" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTSB: 1.09-fold Up; FDR = 0.489; PValue = 0.251; mean CPM = 270.7; cathepsin B" ID="ID_1996155342" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFYB: 1.1-fold Up; FDR = 0.547; PValue = 0.292; mean CPM = 15.90; nuclear transcription factor Y, beta" ID="ID_1962587964" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RFXAP: 1.18-fold Up; FDR = 0.553; PValue = 0.296; mean CPM = 3.588; regulatory factor X-associated protein" ID="ID_29832012" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90AB1: 1.07-fold Down; FDR = 0.652; PValue = 0.369; mean CPM = 905.8; heat shock protein 90kDa alpha (cytosolic), class B member 1" ID="ID_890599779" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90AA1: 1.8-fold Up; FDR = 0.749; PValue = 0.449; mean CPM = 0.8328; heat shock protein 90kDa alpha (cytosolic), class A member 1" ID="ID_1098377766" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD4: 1.27-fold Up; FDR = 0.807; PValue = 0.503; mean CPM = 1.122; CD4 molecule" ID="ID_1887040816" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA6: 1.41-fold Down; FDR = 0.807; PValue = 0.504; mean CPM = 0.8019; interferon, alpha 6" ID="ID_544110996" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA5: 1.05-fold Up; FDR = 0.851; PValue = 0.562; mean CPM = 1754; heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)" ID="ID_555463330" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA4: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 217.6; heat shock 70kDa protein 4" ID="ID_1533270259" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CANX: 1.04-fold Up; FDR = 0.859; PValue = 0.573; mean CPM = 348.2; calnexin" ID="ID_1717750351" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000024066: 1.25-fold Up; FDR = 0.896; PValue = 0.621; mean CPM = 0.7972; Uncharacterized protein" ID="ID_939535283" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DRB: 1.28-fold Up; FDR = 0.898; PValue = 0.624; mean CPM = 0.8112; MHC class II antigen; Uncharacterized protein" ID="ID_1889434208" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KLRC1: 1.14-fold Down; FDR = 0.903; PValue = 0.653; mean CPM = 1.817; killer cell lectin-like receptor subfamily C, member 1" ID="ID_1981760039" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA13: 1.13-fold Up; FDR = 0.908; PValue = 0.677; mean CPM = 0.7960; interferon, alpha 13" ID="ID_723998261" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA2: 1.13-fold Up; FDR = 0.908; PValue = 0.681; mean CPM = 0.7877; HLA class II histocompatibility antigen, DQ alpha 2 chain Precursor (HLA class II histocompatibility antigen, DQ(6) alpha chain)(DX alpha chain)(HLA-DQA1)" ID="ID_1701576609" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA8: 1.13-fold Down; FDR = 0.911; PValue = 0.702; mean CPM = 0.7910; interferon, alpha 8" ID="ID_790725693" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KIR3DL2: 1.18-fold Down; FDR = 0.944; PValue = 0.764; mean CPM = 0.8149; Macaca mulatta killer immunoglobulin-like receptor KIR3DL20 (KIR3DL20), mRNA." ID="ID_1108339632" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA14: 1.22-fold Up; FDR = 0.965; PValue = 0.802; mean CPM = 0.8654; interferon, alpha 14" ID="ID_655508493" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA4: 1.28-fold Down; FDR = 0.983; PValue = 0.829; mean CPM = 0.8584; interferon, alpha 4" ID="ID_1770822983" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSME3: No Change; FDR = 1; PValue = 0.946; mean CPM = 64.75; proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)" ID="ID_394437232" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LGMN: No Change; FDR = 1; PValue = 0.967; mean CPM = 458.0; legumain" ID="ID_1845443490" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD8A: No Change; FDR = 1; PValue = 0.98; mean CPM = 0.8052; CD8a molecule" ID="ID_1157519729" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA1: No Change; FDR = 1; PValue = 0.998; mean CPM = 0.8014; interferon, alpha 1" ID="ID_1265034469" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KLRD1: No Change; FDR = 1; PValue = 1; mean CPM = 0.7825; Macaca mulatta killer cell lectin-like receptor subfamily D, member 1 (KLRD1), mRNA." ID="ID_1185188902" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IFN-gamma: Upregulated, FDR = 0.00688, PValue = 0.000382" ID="ID_351854751" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="SP100: 3.56-fold Up; FDR = 3.74e-26; PValue = 1.58e-29; mean CPM = 187.4; SP100 nuclear antigen" ID="ID_506495570" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF1: 18.6-fold Up; FDR = 1.53e-21; PValue = 4.24e-24; mean CPM = 240.7; interferon regulatory factor 1" ID="ID_373310642" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR3: 10.3-fold Up; FDR = 1.95e-21; PValue = 5.6e-24; mean CPM = 35.70; toll-like receptor 3" ID="ID_1965633786" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF9: 3.85-fold Up; FDR = 2.6e-19; PValue = 1.12e-21; mean CPM = 106.4; interferon regulatory factor 9" ID="ID_1767370607" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_57396855" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_871684762" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF2: 3.25-fold Up; FDR = 2.61e-18; PValue = 1.48e-20; mean CPM = 32.37; interferon regulatory factor 2" ID="ID_812747620" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF7: 14.8-fold Up; FDR = 7.66e-18; PValue = 4.82e-20; mean CPM = 11.54; Macaca mulatta interferon regulatory factor 7 (IRF7), mRNA." ID="ID_177119589" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DMB: 17.5-fold Up; FDR = 2.77e-15; PValue = 2.66e-17; mean CPM = 9.464; HLA class II histocompatibility antigen, DM beta chain Precursor (MHC class II antigen DMB)(Really interesting new gene 7 protein)" ID="ID_439842101" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DPA1: 107-fold Up; FDR = 5.97e-15; PValue = 6.11e-17; mean CPM = 17.08; HLA class II histocompatibility antigen, DP alpha 1 chain Precursor (HLA-SB alpha chain)(MHC class II DP3-alpha)(DP(W3))(DP(W4))" ID="ID_110634606" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DQB1: 31.1-fold Up; FDR = 6.93e-13; PValue = 1.1e-14; mean CPM = 6.675; Macaca mulatta MHC class II antigen (MAMU-DRB), mRNA." ID="ID_1178233863" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD276: 1.83-fold Down; FDR = 2.04e-11; PValue = 4.56e-13; mean CPM = 65.28; CD276 molecule" ID="ID_1237671649" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PML: 2.25-fold Up; FDR = 6.36e-11; PValue = 1.6e-12; mean CPM = 94.89; Uncharacterized protein" ID="ID_1675565773" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN2: 1.87-fold Up; FDR = 6.19e-10; PValue = 2e-11; mean CPM = 32.46; protein tyrosine phosphatase, non-receptor type 2" ID="ID_484011322" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPRU: 2.57-fold Down; FDR = 1.5e-09; PValue = 5.3e-11; mean CPM = 17.80; Uncharacterized protein" ID="ID_1882091415" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF8: 11.4-fold Up; FDR = 6e-09; PValue = 2.46e-10; mean CPM = 5.558; interferon regulatory factor 8" ID="ID_262918498" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA1: 15.1-fold Up; FDR = 1.9e-08; PValue = 8.86e-10; mean CPM = 3.665; HLA class II histocompatibility antigen, DQ alpha 1 chain precursor" ID="ID_497139639" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DPB1: 7.73-fold Up; FDR = 4.73e-08; PValue = 2.45e-09; mean CPM = 1.528; Macaca mulatta major histocompatibility complex, class II, DP beta (MAMU-DPB), mRNA." ID="ID_1829841253" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INHBA: 2.52-fold Down; FDR = 1.51e-07; PValue = 8.85e-09; mean CPM = 229.2; inhibin, beta A" ID="ID_1362777358" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CEBPG: 1.5-fold Up; FDR = 1.48e-05; PValue = 1.46e-06; mean CPM = 31.57; CCAAT/enhancer binding protein (C/EBP), gamma" ID="ID_730772951" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS3: 1.69-fold Up; FDR = 0.000994; PValue = 0.000167; mean CPM = 37.76; suppressor of cytokine signaling 3" ID="ID_656288905" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CISH: 1.95-fold Up; FDR = 0.00116; PValue = 0.0002; mean CPM = 5.083; cytokine inducible SH2-containing protein" ID="ID_54258187" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR1: 1.31-fold Up; FDR = 0.00151; PValue = 0.000268; mean CPM = 37.77; interferon gamma receptor 1" ID="ID_309819071" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIAS1: 1.3-fold Up; FDR = 0.00259; PValue = 0.000498; mean CPM = 29.99; protein inhibitor of activated STAT, 1" ID="ID_650908030" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12A: 2.09-fold Up; FDR = 0.00924; PValue = 0.00215; mean CPM = 2.872; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)" ID="ID_502742443" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL18: 1.5-fold Down; FDR = 0.00981; PValue = 0.0023; mean CPM = 6.489; interleukin 18 (interferon-gamma-inducing factor)" ID="ID_1804440842" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INHA: 1.73-fold Down; FDR = 0.0134; PValue = 0.00329; mean CPM = 4.332; inhibin, alpha" ID="ID_1513644746" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FCGR2B: 2.01-fold Up; FDR = 0.0231; PValue = 0.00623; mean CPM = 1.743; Uncharacterized protein" ID="ID_75471441" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR2: 1.23-fold Up; FDR = 0.0258; PValue = 0.00707; mean CPM = 46.52; interferon gamma receptor 2 (interferon gamma transducer 1)" ID="ID_1218942830" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN1: 1.2-fold Down; FDR = 0.0495; PValue = 0.0152; mean CPM = 35.05; protein tyrosine phosphatase, non-receptor type 1" ID="ID_935420838" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DOA: 2.74-fold Up; FDR = 0.0694; PValue = 0.0227; mean CPM = 0.9089; HLA class II histocompatibility antigen, DO alpha chain Precursor (MHC class II antigen DOA)(MHC DZ alpha)(MHC DN-alpha)" ID="ID_1573510572" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_161326246" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF4: 2.95-fold Down; FDR = 0.124; PValue = 0.0456; mean CPM = 0.9773; interferon regulatory factor 4" ID="ID_1450625913" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FCGR2A: 2.18-fold Up; FDR = 0.172; PValue = 0.0682; mean CPM = 0.9955; Fc fragment of IgG, low affinity IIa, receptor (CD32)" ID="ID_407640112" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EBI3: 1.84-fold Up; FDR = 0.228; PValue = 0.0966; mean CPM = 1.386; Epstein-Barr virus induced 3" ID="ID_1085396379" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL27: 1.82-fold Down; FDR = 0.302; PValue = 0.137; mean CPM = 0.9530; interleukin 27" ID="ID_304376354" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014796: 1.77-fold Up; FDR = 0.381; PValue = 0.182; mean CPM = 0.9085; Uncharacterized protein" ID="ID_373704980" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016250: 1.52-fold Up; FDR = 0.419; PValue = 0.205; mean CPM = 1.143" ID="ID_1176562757" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_1578030658" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF6: 2.34-fold Down; FDR = 0.535; PValue = 0.283; mean CPM = 0.8609; interferon regulatory factor 6" ID="ID_1934506681" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCD: 1.06-fold Up; FDR = 0.696; PValue = 0.404; mean CPM = 37.45; protein kinase C, delta" ID="ID_1656542298" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF9: 1.77-fold Up; FDR = 0.74; PValue = 0.441; mean CPM = 0.8485; fibroblast growth factor 9 (glia-activating factor)" ID="ID_1644651563" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF5: 1.06-fold Down; FDR = 0.85; PValue = 0.561; mean CPM = 9.280; interferon regulatory factor 5" ID="ID_621856762" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR7: 1.37-fold Down; FDR = 0.878; PValue = 0.597; mean CPM = 0.8402; toll-like receptor 7" ID="ID_1205169775" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MT2A: 1.24-fold Up; FDR = 0.893; PValue = 0.618; mean CPM = 0.9117; metallothionein 2A" ID="ID_1044236616" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DRB: 1.28-fold Up; FDR = 0.898; PValue = 0.624; mean CPM = 0.8112; MHC class II antigen; Uncharacterized protein" ID="ID_1724476377" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_129226722" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTAFR: 1.39-fold Down; FDR = 0.906; PValue = 0.67; mean CPM = 0.8209; platelet-activating factor receptor" ID="ID_431950372" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA2: 1.13-fold Up; FDR = 0.908; PValue = 0.681; mean CPM = 0.7877; HLA class II histocompatibility antigen, DQ alpha 2 chain Precursor (HLA class II histocompatibility antigen, DQ(6) alpha chain)(DX alpha chain)(HLA-DQA1)" ID="ID_1667606991" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000028965: 1.11-fold Up; FDR = 0.911; PValue = 0.697; mean CPM = 1.501; Uncharacterized protein" ID="ID_329912133" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12B: 1.07-fold Up; FDR = 0.983; PValue = 0.831; mean CPM = 0.8197; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)" ID="ID_930664774" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR9: 1.01-fold Down; FDR = 1; PValue = 0.859; mean CPM = 21.45; Macaca mulatta toll-like receptor 9 (TLR9), mRNA." ID="ID_1464731670" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="REG1A: No Change; FDR = 1; PValue = 1; mean CPM = 0.7990; regenerating islet-derived 1 alpha" ID="ID_779392257" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="REG1A: No Change; FDR = 1; PValue = 1; mean CPM = 0.7825; Uncharacterized protein" ID="ID_1630935857" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000025091: No Change; FDR = 1; PValue = 1; mean CPM = 0.7808; Uncharacterized protein" ID="ID_625744684" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLA2G2A: No Change; FDR = 1; PValue = 1; mean CPM = 0.7858; phospholipase A2, group IIA (platelets, synovial fluid)" ID="ID_522028882" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-21: Upregulated, FDR = 0.0446, PValue = 0.00331" ID="ID_139257637" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_866098690" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_7411832" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_951996220" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BID: 1.66-fold Up; FDR = 5.41e-09; PValue = 2.19e-10; mean CPM = 35.19; BH3 interacting domain death agonist" ID="ID_1243829448" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1B: 1.64-fold Up; FDR = 1.22e-08; PValue = 5.39e-10; mean CPM = 32.96; Cyclin-dependent kinase inhibitor 1B; Uncharacterized protein" ID="ID_1613076463" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRDM1: 3.05-fold Up; FDR = 3.55e-08; PValue = 1.78e-09; mean CPM = 8.715; PR domain containing 1, with ZNF domain" ID="ID_1736829012" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_696925616" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L1: 1.51-fold Up; FDR = 9.13e-07; PValue = 6.52e-08; mean CPM = 66.15; Bcl-2-like protein 1; Bcl-2-like protein 1 isoform 1; Uncharacterized protein" ID="ID_1327321430" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17B: 4.36-fold Down; FDR = 2.84e-06; PValue = 2.29e-07; mean CPM = 1.984; interleukin 17B" ID="ID_561996203" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PARP1: 1.46-fold Down; FDR = 0.00173; PValue = 0.000315; mean CPM = 46.95; poly (ADP-ribose) polymerase 1" ID="ID_165871302" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK3: 2.31-fold Up; FDR = 0.00186; PValue = 0.000342; mean CPM = 2.154; Janus kinase 3" ID="ID_753103823" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL20: 2.09-fold Up; FDR = 0.0108; PValue = 0.00256; mean CPM = 60.21; Macaca mulatta chemokine (C-C motif) ligand 20 (CCL20), mRNA." ID="ID_667378598" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSF2: 2.96-fold Down; FDR = 0.0174; PValue = 0.00447; mean CPM = 73.98; colony stimulating factor 2 (granulocyte-macrophage)" ID="ID_190494718" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17D: 1.45-fold Down; FDR = 0.0235; PValue = 0.00633; mean CPM = 5.355; interleukin 17D" ID="ID_152638017" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL18RAP: 2.95-fold Down; FDR = 0.0275; PValue = 0.00761; mean CPM = 1.220; interleukin 18 receptor accessory protein" ID="ID_80479716" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L11: 1.34-fold Up; FDR = 0.0609; PValue = 0.0195; mean CPM = 18.38; BCL2-like 11 (apoptosis facilitator)" ID="ID_1302132270" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_1400224508" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1980941366" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12RB2: 1.42-fold Down; FDR = 0.299; PValue = 0.135; mean CPM = 1.728; interleukin 12 receptor, beta 2" ID="ID_809484279" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL21R: 1.56-fold Down; FDR = 0.534; PValue = 0.282; mean CPM = 1.021; interleukin 21 receptor" ID="ID_1430530927" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_172848551" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL6: 1.06-fold Down; FDR = 0.837; PValue = 0.542; mean CPM = 64.49; B-cell CLL/lymphoma 6" ID="ID_1661229815" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_472315688" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL25: 1.24-fold Down; FDR = 0.899; PValue = 0.631; mean CPM = 0.7976; interleukin 25" ID="ID_712887158" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17A: 1.12-fold Up; FDR = 0.911; PValue = 0.706; mean CPM = 0.7895; interleukin 17A" ID="ID_1262206325" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2RA: 1.08-fold Up; FDR = 0.945; PValue = 0.766; mean CPM = 0.8493; interleukin 2 receptor, alpha" ID="ID_1944228204" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17F: 1.11-fold Down; FDR = 0.948; PValue = 0.771; mean CPM = 1.150; interleukin 17F" ID="ID_1691865244" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL21: 1.04-fold Up; FDR = 0.948; PValue = 0.773; mean CPM = 0.8164; interleukin 21" ID="ID_1455413095" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBX21: 1.09-fold Up; FDR = 0.972; PValue = 0.813; mean CPM = 0.9978; T-box 21" ID="ID_497702296" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="NLR signaling: Upregulated, FDR = 0.11, PValue = 0.0118" ID="ID_618534072" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CASP5: 68-fold Up; FDR = 3.54e-19; PValue = 1.64e-21; mean CPM = 7.240; caspase 5, apoptosis-related cysteine peptidase" ID="ID_500590037" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_922262874" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK2: 3.75-fold Up; FDR = 6.1e-16; PValue = 5.38e-18; mean CPM = 68.21; receptor-interacting serine-threonine kinase 2" ID="ID_1349823423" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL2: 24.6-fold Up; FDR = 1.83e-15; PValue = 1.69e-17; mean CPM = 668.2; Macaca mulatta chemokine (C-C motif) ligand 2 (CCL2), mRNA." ID="ID_1972624919" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CARD6: 2.33-fold Up; FDR = 1.15e-12; PValue = 1.89e-14; mean CPM = 30.09; caspase recruitment domain family, member 6" ID="ID_1280595535" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CARD8: 2.48-fold Up; FDR = 2.44e-11; PValue = 5.59e-13; mean CPM = 14.84; caspase recruitment domain family, member 8" ID="ID_993372721" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC2: 1.96-fold Up; FDR = 1.01e-10; PValue = 2.62e-12; mean CPM = 53.58; baculoviral IAP repeat-containing 2" ID="ID_1243768991" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL13: 12.3-fold Up; FDR = 4.33e-10; PValue = 1.35e-11; mean CPM = 3.824; chemokine (C-C motif) ligand 13" ID="ID_998792027" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CARD8: 2.02-fold Up; FDR = 1.41e-09; PValue = 4.93e-11; mean CPM = 15.89; caspase recruitment domain family, member 8" ID="ID_1648524895" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL7: 8.24-fold Up; FDR = 6.67e-09; PValue = 2.75e-10; mean CPM = 8.249; chemokine (C-C motif) ligand 7" ID="ID_521039410" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_535018405" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLRC4: 6.6-fold Up; FDR = 8.52e-08; PValue = 4.67e-09; mean CPM = 3.347; NLR family, CARD domain containing 4" ID="ID_203897853" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL5: 6.74-fold Up; FDR = 2.65e-07; PValue = 1.64e-08; mean CPM = 30.35; chemokine (C-C motif) ligand 5" ID="ID_806064520" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC3: 2.79-fold Up; FDR = 1.74e-06; PValue = 1.32e-07; mean CPM = 95.34; baculoviral IAP repeat-containing 3" ID="ID_1596410800" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1788899075" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL11: 6.86-fold Up; FDR = 2.69e-05; PValue = 2.82e-06; mean CPM = 4.204; chemokine (C-C motif) ligand 11" ID="ID_93759375" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFAIP3: 1.79-fold Up; FDR = 3.14e-05; PValue = 3.34e-06; mean CPM = 52.47; tumor necrosis factor, alpha-induced protein 3" ID="ID_1194226787" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90AA1: 1.41-fold Up; FDR = 4.17e-05; PValue = 4.62e-06; mean CPM = 609.6; heat shock protein 90kDa alpha (cytosolic), class A member 2" ID="ID_199110770" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CARD9: 1.53-fold Up; FDR = 9.57e-05; PValue = 1.18e-05; mean CPM = 16.72; caspase recruitment domain family, member 9" ID="ID_507283233" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP2: 1.45-fold Up; FDR = 0.000179; PValue = 2.4e-05; mean CPM = 65.31; TGF-beta activated kinase 1/MAP3K7 binding protein 2" ID="ID_983383000" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOD1: 1.63-fold Up; FDR = 0.000193; PValue = 2.61e-05; mean CPM = 58.36; nucleotide-binding oligomerization domain containing 1" ID="ID_119391968" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SUGT1: 1.35-fold Up; FDR = 0.000193; PValue = 2.61e-05; mean CPM = 54.75; SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)" ID="ID_1677897607" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP3: 1.5-fold Up; FDR = 0.000276; PValue = 3.92e-05; mean CPM = 11.67; TGF-beta activated kinase 1/MAP3K7 binding protein 3" ID="ID_1284336318" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1272639725" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90B1: 1.28-fold Down; FDR = 0.00538; PValue = 0.00115; mean CPM = 1017; heat shock protein 90kDa beta (Grp94), member 1" ID="ID_1790065965" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_5874238" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL1: 2.18-fold Up; FDR = 0.00609; PValue = 0.00133; mean CPM = 45.92; chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)" ID="ID_83085593" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL8: 3.3-fold Up; FDR = 0.00609; PValue = 0.00133; mean CPM = 1.313; chemokine (C-C motif) ligand 8" ID="ID_1033264612" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL18: 1.5-fold Down; FDR = 0.00981; PValue = 0.0023; mean CPM = 6.489; interleukin 18 (interferon-gamma-inducing factor)" ID="ID_1886261257" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_227453515" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL8: 2.33-fold Up; FDR = 0.0209; PValue = 0.00552; mean CPM = 2326; interleukin 8" ID="ID_1669478562" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_211272852" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_1613721684" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_749441993" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XIAP: 1.17-fold Up; FDR = 0.177; PValue = 0.0706; mean CPM = 19.21; X-linked inhibitor of apoptosis" ID="ID_47611658" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PYCARD: 1.38-fold Down; FDR = 0.241; PValue = 0.103; mean CPM = 3.110; PYD and CARD domain containing" ID="ID_639542762" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLRP3: 1.84-fold Down; FDR = 0.32; PValue = 0.147; mean CPM = 0.9630; NLR family, pyrin domain containing 3" ID="ID_585371331" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP1: 1.12-fold Down; FDR = 0.351; PValue = 0.165; mean CPM = 17.96; TGF-beta activated kinase 1/MAP3K7 binding protein 1" ID="ID_37569442" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_1355938855" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1367591995" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK12: 1.19-fold Down; FDR = 0.422; PValue = 0.208; mean CPM = 6.569; mitogen-activated protein kinase 12" ID="ID_1030053209" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1003081961" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK13: 1.22-fold Down; FDR = 0.536; PValue = 0.284; mean CPM = 3.100; mitogen-activated protein kinase 13" ID="ID_1738625353" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90AB1: 1.07-fold Down; FDR = 0.652; PValue = 0.369; mean CPM = 905.8; heat shock protein 90kDa alpha (cytosolic), class B member 1" ID="ID_1416049969" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_132473864" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90AA1: 1.8-fold Up; FDR = 0.749; PValue = 0.449; mean CPM = 0.8328; heat shock protein 90kDa alpha (cytosolic), class A member 1" ID="ID_1904777687" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MEFV: 1.13-fold Up; FDR = 0.813; PValue = 0.51; mean CPM = 6.740; Mediterranean fever" ID="ID_778955691" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1573023825" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOD2: 1.17-fold Up; FDR = 0.866; PValue = 0.583; mean CPM = 1.911; nucleotide-binding oligomerization domain containing 2" ID="ID_417922417" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_1146908257" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_824214533" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRIP6: 1.01-fold Down; FDR = 1; PValue = 0.92; mean CPM = 125.6; thyroid hormone receptor interactor 6" ID="ID_1491999781" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSTPIP1: 1.03-fold Down; FDR = 1; PValue = 0.929; mean CPM = 1.615; proline-serine-threonine phosphatase interacting protein 1" ID="ID_1539956168" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_431458930" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-22: Upregulated, FDR = 0.11, PValue = 0.0122" ID="ID_1824179518" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="STAT2: 2.67-fold Up; FDR = 8.02e-19; PValue = 4.03e-21; mean CPM = 185.6; signal transducer and activator of transcription 2, 113kDa" ID="ID_61459466" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_213837267" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_663927242" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5A: 2.28-fold Up; FDR = 6.87e-14; PValue = 8.58e-16; mean CPM = 21.55; signal transducer and activator of transcription 5A" ID="ID_180317247" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_933249176" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_1049584657" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1973198707" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_218321635" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT4: 1.79-fold Up; FDR = 2.3e-05; PValue = 2.36e-06; mean CPM = 26.79; signal transducer and activator of transcription 4" ID="ID_1431731369" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS3: 1.69-fold Up; FDR = 0.000994; PValue = 0.000167; mean CPM = 37.76; suppressor of cytokine signaling 3" ID="ID_1082000887" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK3: 2.31-fold Up; FDR = 0.00186; PValue = 0.000342; mean CPM = 2.154; Janus kinase 3" ID="ID_691468298" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYK2: 1.24-fold Down; FDR = 0.0142; PValue = 0.00354; mean CPM = 42.58; tyrosine kinase 2" ID="ID_1519575304" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_935484245" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1103979667" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_664745677" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_1773279416" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_187952600" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1429576867" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL10RA: 1.55-fold Down; FDR = 0.516; PValue = 0.269; mean CPM = 0.9545; interleukin 10 receptor, alpha" ID="ID_1944911564" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL22RA1: 1.26-fold Up; FDR = 0.846; PValue = 0.555; mean CPM = 0.9674; interleukin 22 receptor, alpha 1" ID="ID_1286750174" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL22RA2: 1.2-fold Down; FDR = 0.899; PValue = 0.629; mean CPM = 0.7954; interleukin 22 receptor, alpha 2" ID="ID_418849927" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL22: 1.33-fold Down; FDR = 0.928; PValue = 0.735; mean CPM = 0.8193; interleukin 22" ID="ID_353304482" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-13: Upregulated, FDR = 0.139, PValue = 0.018" ID="ID_1117343564" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_11770930" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DMB: 17.5-fold Up; FDR = 2.77e-15; PValue = 2.66e-17; mean CPM = 9.464; HLA class II histocompatibility antigen, DM beta chain Precursor (MHC class II antigen DMB)(Really interesting new gene 7 protein)" ID="ID_1611202251" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DPA1: 107-fold Up; FDR = 5.97e-15; PValue = 6.11e-17; mean CPM = 17.08; HLA class II histocompatibility antigen, DP alpha 1 chain Precursor (HLA-SB alpha chain)(MHC class II DP3-alpha)(DP(W3))(DP(W4))" ID="ID_1716869498" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DQB1: 31.1-fold Up; FDR = 6.93e-13; PValue = 1.1e-14; mean CPM = 6.675; Macaca mulatta MHC class II antigen (MAMU-DRB), mRNA." ID="ID_1189246634" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_1398022656" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL13RA1: 1.73-fold Up; FDR = 1.81e-09; PValue = 6.5e-11; mean CPM = 42.50; interleukin 13 receptor, alpha 1" ID="ID_1452674622" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_1483637947" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRS1: 2.78-fold Up; FDR = 7.67e-09; PValue = 3.19e-10; mean CPM = 26.55; Uncharacterized protein" ID="ID_1768861507" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA1: 15.1-fold Up; FDR = 1.9e-08; PValue = 8.86e-10; mean CPM = 3.665; HLA class II histocompatibility antigen, DQ alpha 1 chain precursor" ID="ID_706204867" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DPB1: 7.73-fold Up; FDR = 4.73e-08; PValue = 2.45e-09; mean CPM = 1.528; Macaca mulatta major histocompatibility complex, class II, DP beta (MAMU-DPB), mRNA." ID="ID_220540630" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_751157983" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_212824425" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CISH: 1.95-fold Up; FDR = 0.00116; PValue = 0.0002; mean CPM = 5.083; cytokine inducible SH2-containing protein" ID="ID_632425587" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK3: 2.31-fold Up; FDR = 0.00186; PValue = 0.000342; mean CPM = 2.154; Janus kinase 3" ID="ID_854835744" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYK2: 1.24-fold Down; FDR = 0.0142; PValue = 0.00354; mean CPM = 42.58; tyrosine kinase 2" ID="ID_1958644321" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB2: 1.55-fold Down; FDR = 0.0187; PValue = 0.00485; mean CPM = 34.87; Integrin beta" ID="ID_1409750662" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VCAM1: 1.53-fold Up; FDR = 0.0353; PValue = 0.0102; mean CPM = 110.0; vascular cell adhesion molecule 1" ID="ID_1796360545" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DOA: 2.74-fold Up; FDR = 0.0694; PValue = 0.0227; mean CPM = 0.9089; HLA class II histocompatibility antigen, DO alpha chain Precursor (MHC class II antigen DOA)(MHC DZ alpha)(MHC DN-alpha)" ID="ID_491618261" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT6: 1.18-fold Up; FDR = 0.0727; PValue = 0.024; mean CPM = 217.5; signal transducer and activator of transcription 6, interleukin-4 induced" ID="ID_1011421633" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB1: 1.23-fold Up; FDR = 0.0759; PValue = 0.0253; mean CPM = 2700; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)" ID="ID_892050043" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL13RA2: 2.13-fold Up; FDR = 0.0909; PValue = 0.0313; mean CPM = 1.485; Interleukin-13 receptor subunit alpha-2; Uncharacterized protein" ID="ID_586303310" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_631680529" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS2: 1.17-fold Up; FDR = 0.1; PValue = 0.0353; mean CPM = 31.79; son of sevenless homolog 2 (Drosophila)" ID="ID_343722313" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1010731538" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_982401893" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014796: 1.77-fold Up; FDR = 0.381; PValue = 0.182; mean CPM = 0.9085; Uncharacterized protein" ID="ID_1312935817" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_271088193" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_1599436853" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_1908959463" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAM: 1.44-fold Down; FDR = 0.73; PValue = 0.432; mean CPM = 0.9052; integrin, alpha M (complement component 3 receptor 3 subunit)" ID="ID_124820153" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL4R: 1.05-fold Down; FDR = 0.803; PValue = 0.499; mean CPM = 193.5; interleukin 4 receptor" ID="ID_991310152" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FCER2: 1.41-fold Up; FDR = 0.864; PValue = 0.58; mean CPM = 0.8258; Fc fragment of IgE, low affinity II, receptor for (CD23)" ID="ID_1779949462" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DRB: 1.28-fold Up; FDR = 0.898; PValue = 0.624; mean CPM = 0.8112; MHC class II antigen; Uncharacterized protein" ID="ID_1370086258" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA2: 1.13-fold Up; FDR = 0.908; PValue = 0.681; mean CPM = 0.7877; HLA class II histocompatibility antigen, DQ alpha 2 chain Precursor (HLA class II histocompatibility antigen, DQ(6) alpha chain)(DX alpha chain)(HLA-DQA1)" ID="ID_827335611" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL13: 1.05-fold Up; FDR = 0.967; PValue = 0.805; mean CPM = 0.8212; interleukin 13" ID="ID_526090660" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="NF-kappaB pathway: Upregulated, FDR = 0.181, PValue = 0.0269" ID="ID_162186141" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TLR2: 8.94-fold Up; FDR = 6.97e-23; PValue = 1.25e-25; mean CPM = 18.41; toll-like receptor 2" ID="ID_1249147710" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR3: 10.3-fold Up; FDR = 1.95e-21; PValue = 5.6e-24; mean CPM = 35.70; toll-like receptor 3" ID="ID_287147256" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_705512714" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICAM1: 24.6-fold Up; FDR = 2.39e-17; PValue = 1.64e-19; mean CPM = 232.4; intercellular adhesion molecule 1" ID="ID_633394529" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_1124540667" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF10: 44.5-fold Up; FDR = 2.83e-16; PValue = 2.4e-18; mean CPM = 6.029; Tumor necrosis factor ligand superfamily member 10 isoform 1; Uncharacterized protein" ID="ID_1813204492" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL2: 24.6-fold Up; FDR = 1.83e-15; PValue = 1.69e-17; mean CPM = 668.2; Macaca mulatta chemokine (C-C motif) ligand 2 (CCL2), mRNA." ID="ID_314615507" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC2: 1.96-fold Up; FDR = 1.01e-10; PValue = 2.62e-12; mean CPM = 53.58; baculoviral IAP repeat-containing 2" ID="ID_1586949985" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR4: 3.45-fold Up; FDR = 3.1e-09; PValue = 1.19e-10; mean CPM = 7.456; Macaca mulatta toll-like receptor 4 (TLR4), mRNA." ID="ID_1738839839" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_723496442" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_687198063" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF1: 1.51-fold Up; FDR = 5.28e-06; PValue = 4.58e-07; mean CPM = 22.13; activating transcription factor 1" ID="ID_199714541" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL10: 1.55-fold Up; FDR = 5.92e-06; PValue = 5.22e-07; mean CPM = 21.83; B-cell CLL/lymphoma 10" ID="ID_112400456" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFAIP3: 1.79-fold Up; FDR = 3.14e-05; PValue = 3.34e-06; mean CPM = 52.47; tumor necrosis factor, alpha-induced protein 3" ID="ID_33225304" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1R1: 1.6-fold Up; FDR = 3.35e-05; PValue = 3.61e-06; mean CPM = 123.7; interleukin 1 receptor, type I" ID="ID_497215784" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HMOX1: 1.94-fold Up; FDR = 7.83e-05; PValue = 9.42e-06; mean CPM = 15.01; heme oxygenase (decycling) 1" ID="ID_672904888" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_999755107" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GJA1: 1.71-fold Up; FDR = 0.000117; PValue = 1.47e-05; mean CPM = 2600; gap junction protein, alpha 1, 43kDa" ID="ID_627220076" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOD1: 1.63-fold Up; FDR = 0.000193; PValue = 2.61e-05; mean CPM = 58.36; nucleotide-binding oligomerization domain containing 1" ID="ID_564970436" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40: 2.76-fold Up; FDR = 0.00039; PValue = 5.79e-05; mean CPM = 9.139; CD40 molecule, TNF receptor superfamily member 5" ID="ID_1630347397" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_909907728" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRIM13: 1.38-fold Up; FDR = 0.0009; PValue = 0.000149; mean CPM = 19.75; tripartite motif-containing 13" ID="ID_299560785" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPM1A: 1.31-fold Up; FDR = 0.00101; PValue = 0.00017; mean CPM = 60.08; protein phosphatase, Mg2+/Mn2+ dependent, 1A" ID="ID_592329417" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC44A2: 1.31-fold Down; FDR = 0.00108; PValue = 0.000185; mean CPM = 154.3; solute carrier family 44, member 2" ID="ID_1730831923" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="REL: 1.46-fold Down; FDR = 0.00272; PValue = 0.000526; mean CPM = 10.17; v-rel avian reticuloendotheliosis viral oncogene homolog" ID="ID_428818491" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHOA: 1.28-fold Down; FDR = 0.00295; PValue = 0.000575; mean CPM = 277.8; ras homolog gene family, member A" ID="ID_308731012" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBK1: 1.3-fold Up; FDR = 0.00337; PValue = 0.000674; mean CPM = 30.46; TANK-binding kinase 1" ID="ID_129614188" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL20: 2.09-fold Up; FDR = 0.0108; PValue = 0.00256; mean CPM = 60.21; Macaca mulatta chemokine (C-C motif) ligand 20 (CCL20), mRNA." ID="ID_144923723" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSF2: 2.96-fold Down; FDR = 0.0174; PValue = 0.00447; mean CPM = 73.98; colony stimulating factor 2 (granulocyte-macrophage)" ID="ID_1972605509" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HTR2B: 1.75-fold Up; FDR = 0.0194; PValue = 0.0051; mean CPM = 14.36; 5-hydroxytryptamine (serotonin) receptor 2B" ID="ID_992002498" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL8: 2.33-fold Up; FDR = 0.0209; PValue = 0.00552; mean CPM = 2326; interleukin 8" ID="ID_588499911" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_273273785" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_49512916" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRADD: 1.22-fold Up; FDR = 0.0319; PValue = 0.00907; mean CPM = 34.75; TNFRSF1A-associated via death domain" ID="ID_1679504656" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_689459641" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL3: 1.25-fold Up; FDR = 0.0559; PValue = 0.0175; mean CPM = 16.96; B-cell CLL/lymphoma 3" ID="ID_468855960" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELB: 1.22-fold Down; FDR = 0.0606; PValue = 0.0193; mean CPM = 26.64; v-rel reticuloendotheliosis viral oncogene homolog B" ID="ID_666902068" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSF3: 2.55-fold Up; FDR = 0.0701; PValue = 0.023; mean CPM = 72.12; colony stimulating factor 3 (granulocyte)" ID="ID_353989332" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FADD: 1.18-fold Down; FDR = 0.0936; PValue = 0.0324; mean CPM = 30.89; Uncharacterized protein" ID="ID_1730110810" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_1949369382" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_653495656" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC20A1: 1.18-fold Up; FDR = 0.244; PValue = 0.105; mean CPM = 117.7; solute carrier family 20 (phosphate transporter), member 1" ID="ID_13052449" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK2: 1.27-fold Down; FDR = 0.259; PValue = 0.113; mean CPM = 10.13; interleukin-1 receptor-associated kinase 2" ID="ID_1698330393" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1A: 1.11-fold Up; FDR = 0.297; PValue = 0.134; mean CPM = 134.7; tumor necrosis factor receptor superfamily, member 1A" ID="ID_1157140439" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1A: 1.5-fold Up; FDR = 0.315; PValue = 0.144; mean CPM = 155.4; interleukin 1, alpha" ID="ID_735772369" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGR1: 1.19-fold Down; FDR = 0.321; PValue = 0.147; mean CPM = 90.45; Early growth response protein 1; Uncharacterized protein" ID="ID_831621904" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF10B: 1.13-fold Down; FDR = 0.343; PValue = 0.16; mean CPM = 40.59; tumor necrosis factor receptor superfamily, member 10b" ID="ID_1071874421" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MALT1: 1.11-fold Down; FDR = 0.35; PValue = 0.164; mean CPM = 42.89; mucosa associated lymphoid tissue lymphoma translocation gene 1" ID="ID_1240422277" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TICAM1: 1.11-fold Down; FDR = 0.398; PValue = 0.192; mean CPM = 26.73; toll-like receptor adaptor molecule 1" ID="ID_409263738" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="F2R: 1.1-fold Up; FDR = 0.458; PValue = 0.23; mean CPM = 35.05; coagulation factor II (thrombin) receptor" ID="ID_390043977" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD27: 1.52-fold Down; FDR = 0.547; PValue = 0.292; mean CPM = 1.004; CD27 molecule" ID="ID_399570516" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000000985: 1.2-fold Up; FDR = 0.569; PValue = 0.307; mean CPM = 11.32; Uncharacterized protein" ID="ID_769859780" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_1947382526" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LTBR: 1.06-fold Down; FDR = 0.683; PValue = 0.394; mean CPM = 91.13; lymphotoxin beta receptor (TNFR superfamily, member 3)" ID="ID_285598881" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNB1: 1.79-fold Up; FDR = 0.731; PValue = 0.433; mean CPM = 0.8526; interferon, beta 1, fibroblast" ID="ID_1167386627" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF10A: 1.06-fold Down; FDR = 0.732; PValue = 0.434; mean CPM = 42.75; tumor necrosis factor receptor superfamily, member 10a" ID="ID_383122772" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMED4: 1.06-fold Down; FDR = 0.74; PValue = 0.441; mean CPM = 69.78; transmembrane emp24 protein transport domain containing 4" ID="ID_1973071894" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR6: 1.07-fold Down; FDR = 0.84; PValue = 0.546; mean CPM = 7.909; toll-like receptor 6" ID="ID_1949428190" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_408651723" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR7: 1.37-fold Down; FDR = 0.878; PValue = 0.597; mean CPM = 0.8402; toll-like receptor 7" ID="ID_1154518704" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK1: 1.04-fold Down; FDR = 0.885; PValue = 0.606; mean CPM = 41.54; interleukin-1 receptor-associated kinase 1" ID="ID_1908123587" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_1707834773" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_168080428" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF14: 1.16-fold Down; FDR = 0.903; PValue = 0.645; mean CPM = 0.7940; tumor necrosis factor (ligand) superfamily, member 14" ID="ID_537112771" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKE: 1.03-fold Up; FDR = 0.929; PValue = 0.737; mean CPM = 21.61; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon" ID="ID_1460053012" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FASLG: 1.2-fold Down; FDR = 0.941; PValue = 0.757; mean CPM = 0.8088; Fas ligand (TNF superfamily, member 6)" ID="ID_567198516" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_412479673" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR9: 1.01-fold Down; FDR = 1; PValue = 0.859; mean CPM = 21.45; Macaca mulatta toll-like receptor 9 (TLR9), mRNA." ID="ID_1005903290" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EDARADD: 1.04-fold Up; FDR = 1; PValue = 0.885; mean CPM = 1.496; EDAR-associated death domain" ID="ID_185340821" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR1: 1.02-fold Up; FDR = 1; PValue = 0.945; mean CPM = 1.221; toll-like receptor 1" ID="ID_453464604" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL10: 1.21-fold Down; FDR = 1; PValue = 0.964; mean CPM = 0.8614; interleukin 10" ID="ID_1899872655" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AGT: 1.02-fold Down; FDR = 1; PValue = 0.996; mean CPM = 0.8004; angiotensinogen (serpin peptidase inhibitor, clade A, member 8)" ID="ID_1284750580" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA1: No Change; FDR = 1; PValue = 0.998; mean CPM = 0.8014; interferon, alpha 1" ID="ID_1175392852" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Toll-like receptor signaling: Upregulated, FDR = 0.274, PValue = 0.0476" ID="ID_457001702" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TLR2: 8.94-fold Up; FDR = 6.97e-23; PValue = 1.25e-25; mean CPM = 18.41; toll-like receptor 2" ID="ID_1707080081" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL10: 462-fold Up; FDR = 1.01e-21; PValue = 2.65e-24; mean CPM = 286.2; Macaca mulatta chemokine (C-X-C motif) ligand 10 (CXCL10), mRNA." ID="ID_1987002055" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR3: 10.3-fold Up; FDR = 1.95e-21; PValue = 5.6e-24; mean CPM = 35.70; toll-like receptor 3" ID="ID_1860862344" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL11: 256-fold Up; FDR = 1e-19; PValue = 3.96e-22; mean CPM = 84.82; chemokine (C-X-C motif) ligand 11" ID="ID_1586579772" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL9: 345-fold Up; FDR = 4.16e-19; PValue = 1.97e-21; mean CPM = 175.7; Macaca mulatta chemokine (C-X-C motif) ligand 9 (CXCL9), mRNA." ID="ID_1579679745" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1096805134" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF7: 14.8-fold Up; FDR = 7.66e-18; PValue = 4.82e-20; mean CPM = 11.54; Macaca mulatta interferon regulatory factor 7 (IRF7), mRNA." ID="ID_269913513" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_303026506" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LY96: 3.13-fold Up; FDR = 1.27e-10; PValue = 3.43e-12; mean CPM = 6.127; lymphocyte antigen 96" ID="ID_478303423" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR4: 3.45-fold Up; FDR = 3.1e-09; PValue = 1.19e-10; mean CPM = 7.456; Macaca mulatta toll-like receptor 4 (TLR4), mRNA." ID="ID_837610186" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_1109932137" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK4: 1.8-fold Up; FDR = 3.31e-08; PValue = 1.64e-09; mean CPM = 12.89; interleukin-1 receptor-associated kinase 4" ID="ID_737144160" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_249282256" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL5: 6.74-fold Up; FDR = 2.65e-07; PValue = 1.64e-08; mean CPM = 30.35; chemokine (C-C motif) ligand 5" ID="ID_110338184" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1232019364" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD14: 2.75-fold Down; FDR = 6.54e-07; PValue = 4.46e-08; mean CPM = 5.195; CD14 molecule" ID="ID_1866029164" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1939368785" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_341555769" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR2: 1.74-fold Up; FDR = 1.85e-06; PValue = 1.44e-07; mean CPM = 26.05; interferon (alpha, beta and omega) receptor 2" ID="ID_132812249" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1041249343" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K3: 1.45-fold Down; FDR = 7.01e-06; PValue = 6.34e-07; mean CPM = 180.1; mitogen-activated protein kinase kinase 3" ID="ID_1932710195" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_630247304" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPP1: 2.25-fold Down; FDR = 7.74e-05; PValue = 9.29e-06; mean CPM = 35.33; secreted phosphoprotein 1" ID="ID_965574245" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP2: 1.45-fold Up; FDR = 0.000179; PValue = 2.4e-05; mean CPM = 65.31; TGF-beta activated kinase 1/MAP3K7 binding protein 2" ID="ID_1407994339" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40: 2.76-fold Up; FDR = 0.00039; PValue = 5.79e-05; mean CPM = 9.139; CD40 molecule, TNF receptor superfamily member 5" ID="ID_1589299278" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TOLLIP: 1.36-fold Down; FDR = 0.000551; PValue = 8.57e-05; mean CPM = 28.79; Uncharacterized protein" ID="ID_146997914" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTSK: 1.62-fold Down; FDR = 0.00104; PValue = 0.000176; mean CPM = 20.16; cathepsin K" ID="ID_1481211920" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBK1: 1.3-fold Up; FDR = 0.00337; PValue = 0.000674; mean CPM = 30.46; TANK-binding kinase 1" ID="ID_1182124248" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_885303855" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_544855441" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR5: 1.86-fold Down; FDR = 0.00878; PValue = 0.00203; mean CPM = 3.008; toll-like receptor 5" ID="ID_917965616" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12A: 2.09-fold Up; FDR = 0.00924; PValue = 0.00215; mean CPM = 2.872; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)" ID="ID_976447162" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR1: 1.27-fold Up; FDR = 0.0101; PValue = 0.00237; mean CPM = 82.39; Uncharacterized protein" ID="ID_1431038369" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_516265141" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL8: 2.33-fold Up; FDR = 0.0209; PValue = 0.00552; mean CPM = 2326; interleukin 8" ID="ID_1630598817" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1575093790" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_1349129815" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1244136730" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL3: 2.04-fold Down; FDR = 0.067; PValue = 0.0218; mean CPM = 3.575; chemokine (C-C motif) ligand 3" ID="ID_1653501191" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K8: 1.35-fold Down; FDR = 0.0831; PValue = 0.0281; mean CPM = 8.912; mitogen-activated protein kinase kinase kinase 8" ID="ID_1111012974" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FADD: 1.18-fold Down; FDR = 0.0936; PValue = 0.0324; mean CPM = 30.89; Uncharacterized protein" ID="ID_624473500" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_441431131" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_1425595239" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1193710604" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_1569745155" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_1201614883" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP1: 1.12-fold Down; FDR = 0.351; PValue = 0.165; mean CPM = 17.96; TGF-beta activated kinase 1/MAP3K7 binding protein 1" ID="ID_158768338" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_621461468" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TICAM1: 1.11-fold Down; FDR = 0.398; PValue = 0.192; mean CPM = 26.73; toll-like receptor adaptor molecule 1" ID="ID_1320029887" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_1319830729" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_741814894" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK12: 1.19-fold Down; FDR = 0.422; PValue = 0.208; mean CPM = 6.569; mitogen-activated protein kinase 12" ID="ID_490850234" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1977330332" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_246531794" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK13: 1.22-fold Down; FDR = 0.536; PValue = 0.284; mean CPM = 3.100; mitogen-activated protein kinase 13" ID="ID_1136851726" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LBP: 1.52-fold Down; FDR = 0.591; PValue = 0.324; mean CPM = 0.8819; lipopolysaccharide binding protein" ID="ID_413370190" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF3: 1.07-fold Up; FDR = 0.611; PValue = 0.338; mean CPM = 34.56; TNF receptor-associated factor 3" ID="ID_1912677820" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_831970792" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNB1: 1.79-fold Up; FDR = 0.731; PValue = 0.433; mean CPM = 0.8526; interferon, beta 1, fibroblast" ID="ID_1023845341" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA6: 1.41-fold Down; FDR = 0.807; PValue = 0.504; mean CPM = 0.8019; interferon, alpha 6" ID="ID_600177831" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR6: 1.07-fold Down; FDR = 0.84; PValue = 0.546; mean CPM = 7.909; toll-like receptor 6" ID="ID_825609858" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TIRAP: 1.07-fold Up; FDR = 0.841; PValue = 0.548; mean CPM = 8.693; Macaca mulatta toll-interleukin 1 receptor (TIR) domain containing adaptor protein (TIRAP), mRNA." ID="ID_1487946178" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF5: 1.06-fold Down; FDR = 0.85; PValue = 0.561; mean CPM = 9.280; interferon regulatory factor 5" ID="ID_1082040400" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_410942585" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1232614450" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR7: 1.37-fold Down; FDR = 0.878; PValue = 0.597; mean CPM = 0.8402; toll-like receptor 7" ID="ID_1705074398" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK1: 1.04-fold Down; FDR = 0.885; PValue = 0.606; mean CPM = 41.54; interleukin-1 receptor-associated kinase 1" ID="ID_1882874170" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_509925002" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA13: 1.13-fold Up; FDR = 0.908; PValue = 0.677; mean CPM = 0.7960; interferon, alpha 13" ID="ID_903683634" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA8: 1.13-fold Down; FDR = 0.911; PValue = 0.702; mean CPM = 0.7910; interferon, alpha 8" ID="ID_1704314699" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKE: 1.03-fold Up; FDR = 0.929; PValue = 0.737; mean CPM = 21.61; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon" ID="ID_974840492" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA14: 1.22-fold Up; FDR = 0.965; PValue = 0.802; mean CPM = 0.8654; interferon, alpha 14" ID="ID_795457374" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_1226508821" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD80: 1.08-fold Up; FDR = 0.971; PValue = 0.812; mean CPM = 1.157; CD80 molecule" ID="ID_1506443771" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_781382509" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA4: 1.28-fold Down; FDR = 0.983; PValue = 0.829; mean CPM = 0.8584; interferon, alpha 4" ID="ID_193899652" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12B: 1.07-fold Up; FDR = 0.983; PValue = 0.831; mean CPM = 0.8197; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)" ID="ID_1063054798" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_1343162681" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR9: 1.01-fold Down; FDR = 1; PValue = 0.859; mean CPM = 21.45; Macaca mulatta toll-like receptor 9 (TLR9), mRNA." ID="ID_1655714342" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR1: 1.02-fold Up; FDR = 1; PValue = 0.945; mean CPM = 1.221; toll-like receptor 1" ID="ID_1892498507" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD86: 1.01-fold Down; FDR = 1; PValue = 0.99; mean CPM = 0.8012; CD86 molecule" ID="ID_273812707" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA1: No Change; FDR = 1; PValue = 0.998; mean CPM = 0.8014; interferon, alpha 1" ID="ID_1907445860" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- </node>
- <node TEXT="globaltest gene set test" ID="ID_340163095" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="IFN alpha/beta: FDR = 1.61e-25, PValue = 4.04e-27" ID="ID_1694937600" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TAP1: 8.86-fold Up; FDR = 4.25e-27; PValue = 3.99e-31; mean CPM = 524.4; Antigen peptide transporter 1 (APT1)(Peptide transporter TAP1)(ATP-binding cassette sub-family B member 2)(Peptide supply factor 1)(Peptide transporter PSF1)(PSF-1)(Peptide transporter involved in antigen processing 1)(Really interesting new gene 4 /.../n)" ID="ID_800041088" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMB8: 15.4-fold Up; FDR = 1.64e-26; PValue = 5.69e-30; mean CPM = 246.0; proteasome subunit beta type-8 isoform E1 proprotein" ID="ID_1403975743" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFITM1: 22.3-fold Up; FDR = 1.43e-23; PValue = 2.15e-26; mean CPM = 454.0; interferon induced transmembrane protein 1" ID="ID_501155959" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFIH1: 14.7-fold Up; FDR = 8.74e-23; PValue = 1.68e-25; mean CPM = 49.84; interferon induced with helicase C domain 1" ID="ID_765220310" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF1: 18.6-fold Up; FDR = 1.53e-21; PValue = 4.24e-24; mean CPM = 240.7; interferon regulatory factor 1" ID="ID_698334568" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="OAS1: 41-fold Up; FDR = 1.01e-20; PValue = 3.28e-23; mean CPM = 37.38; Macaca mulatta 2',5'-oligoadenylate synthetase 1, 40/46kDa (OAS1), mRNA." ID="ID_603024896" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFIT1: 52.1-fold Up; FDR = 1.76e-20; PValue = 6.3e-23; mean CPM = 46.34; interferon-induced protein with tetratricopeptide repeats 1" ID="ID_84860750" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFIT3: 63.7-fold Up; FDR = 7.87e-20; PValue = 3e-22; mean CPM = 372.5; interferon-induced protein with tetratricopeptide repeats 3" ID="ID_650167214" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MX1: 48.9-fold Up; FDR = 9.52e-20; PValue = 3.71e-22; mean CPM = 84.25; myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)" ID="ID_787196295" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF9: 3.85-fold Up; FDR = 2.6e-19; PValue = 1.12e-21; mean CPM = 106.4; interferon regulatory factor 9" ID="ID_628277187" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT2: 2.67-fold Up; FDR = 8.02e-19; PValue = 4.03e-21; mean CPM = 185.6; signal transducer and activator of transcription 2, 113kDa" ID="ID_215968690" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_37711886" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_926964908" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ISG15: 15.5-fold Up; FDR = 2.16e-15; PValue = 2.02e-17; mean CPM = 55.60; ISG15 ubiquitin-like modifier" ID="ID_1423627773" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN2: 1.87-fold Up; FDR = 6.19e-10; PValue = 2e-11; mean CPM = 32.46; protein tyrosine phosphatase, non-receptor type 2" ID="ID_626137787" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1640296678" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR2: 1.74-fold Up; FDR = 1.85e-06; PValue = 1.44e-07; mean CPM = 26.05; interferon (alpha, beta and omega) receptor 2" ID="ID_863143345" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR1: 1.31-fold Up; FDR = 0.00151; PValue = 0.000268; mean CPM = 37.77; interferon gamma receptor 1" ID="ID_1607837111" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIAS1: 1.3-fold Up; FDR = 0.00259; PValue = 0.000498; mean CPM = 29.99; protein inhibitor of activated STAT, 1" ID="ID_861049682" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL18: 1.5-fold Down; FDR = 0.00981; PValue = 0.0023; mean CPM = 6.489; interleukin 18 (interferon-gamma-inducing factor)" ID="ID_1709293780" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR1: 1.27-fold Up; FDR = 0.0101; PValue = 0.00237; mean CPM = 82.39; Uncharacterized protein" ID="ID_378500822" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYK2: 1.24-fold Down; FDR = 0.0142; PValue = 0.00354; mean CPM = 42.58; tyrosine kinase 2" ID="ID_289198708" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR2: 1.23-fold Up; FDR = 0.0258; PValue = 0.00707; mean CPM = 46.52; interferon gamma receptor 2 (interferon gamma transducer 1)" ID="ID_1304742125" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_1734378764" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2: 1.48-fold Up; FDR = 0.384; PValue = 0.184; mean CPM = 1.344; Uncharacterized protein" ID="ID_371466953" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016250: 1.52-fold Up; FDR = 0.419; PValue = 0.205; mean CPM = 1.143" ID="ID_768656942" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNB1: 1.79-fold Up; FDR = 0.731; PValue = 0.433; mean CPM = 0.8526; interferon, beta 1, fibroblast" ID="ID_605039766" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFITM1: 1.63-fold Up; FDR = 0.767; PValue = 0.465; mean CPM = 0.8148; interferon induced transmembrane protein 1 (9-27)" ID="ID_1793736036" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAX: 1.05-fold Up; FDR = 0.809; PValue = 0.506; mean CPM = 162.4; Uncharacterized protein" ID="ID_322787016" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_270055683" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000028965: 1.11-fold Up; FDR = 0.911; PValue = 0.697; mean CPM = 1.501; Uncharacterized protein" ID="ID_808301530" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MED14: 1.01-fold Down; FDR = 1; PValue = 0.916; mean CPM = 56.17; mediator complex subunit 14" ID="ID_1044744570" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA1: No Change; FDR = 1; PValue = 0.998; mean CPM = 0.8014; interferon, alpha 1" ID="ID_1461166078" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Antigen processing and presentation: FDR = 1.61e-25, PValue = 5.97e-27" ID="ID_611488330" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TAP1: 8.86-fold Up; FDR = 4.25e-27; PValue = 3.99e-31; mean CPM = 524.4; Antigen peptide transporter 1 (APT1)(Peptide transporter TAP1)(ATP-binding cassette sub-family B member 2)(Peptide supply factor 1)(Peptide transporter PSF1)(PSF-1)(Peptide transporter involved in antigen processing 1)(Really interesting new gene 4 /.../n)" ID="ID_994909119" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014803: 6.92-fold Up; FDR = 4.41e-27; PValue = 6.21e-31; mean CPM = 361.1; Uncharacterized protein" ID="ID_1501790396" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTSS: 17.2-fold Up; FDR = 6.21e-25; PValue = 3.79e-28; mean CPM = 42.75; cathepsin S" ID="ID_1297955945" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSME1: 5.25-fold Up; FDR = 7.8e-24; PValue = 9.53e-27; mean CPM = 157.6; Uncharacterized protein" ID="ID_553474083" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFI30: 14.5-fold Up; FDR = 1.96e-22; PValue = 4.32e-25; mean CPM = 117.9; interferon, gamma-inducible protein 30" ID="ID_622300565" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000027180: 6.97-fold Up; FDR = 1.24e-21; PValue = 3.39e-24; mean CPM = 285.4; Uncharacterized protein" ID="ID_1215079677" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000027180: 6.97-fold Up; FDR = 1.24e-21; PValue = 3.39e-24; mean CPM = 285.4; Uncharacterized protein" ID="ID_491494462" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000005183: 4.07-fold Up; FDR = 2.87e-21; PValue = 8.51e-24; mean CPM = 164.7; Uncharacterized protein" ID="ID_586104949" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000005183: 4.07-fold Up; FDR = 2.87e-21; PValue = 8.51e-24; mean CPM = 164.7; Uncharacterized protein" ID="ID_1097472531" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-B: 6.07-fold Up; FDR = 2.71e-19; PValue = 1.2e-21; mean CPM = 2098; Uncharacterized protein" ID="ID_1548535467" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CIITA: 45.8-fold Up; FDR = 1.14e-17; PValue = 7.44e-20; mean CPM = 27.80; class II, major histocompatibility complex, transactivator" ID="ID_1810179137" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD74: 104-fold Up; FDR = 6e-17; PValue = 4.54e-19; mean CPM = 141.5; CD74 molecule, major histocompatibility complex, class II invariant chain" ID="ID_1499030383" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DMB: 17.5-fold Up; FDR = 2.77e-15; PValue = 2.66e-17; mean CPM = 9.464; HLA class II histocompatibility antigen, DM beta chain Precursor (MHC class II antigen DMB)(Really interesting new gene 7 protein)" ID="ID_1825378343" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DPA1: 107-fold Up; FDR = 5.97e-15; PValue = 6.11e-17; mean CPM = 17.08; HLA class II histocompatibility antigen, DP alpha 1 chain Precursor (HLA-SB alpha chain)(MHC class II DP3-alpha)(DP(W3))(DP(W4))" ID="ID_1428230493" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA2: 4.21-fold Down; FDR = 2.4e-14; PValue = 2.77e-16; mean CPM = 66.42; heat shock 70kDa protein 2" ID="ID_808135962" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DQB1: 31.1-fold Up; FDR = 6.93e-13; PValue = 1.1e-14; mean CPM = 6.675; Macaca mulatta MHC class II antigen (MAMU-DRB), mRNA." ID="ID_1828699194" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA1B: 2.24-fold Down; FDR = 4.33e-09; PValue = 1.71e-10; mean CPM = 44.90; Heat shock 70 kDa protein 1A/1B (Heat shock 70 kDa protein 1/2)(HSP70.1/HSP70.2)(HSP70-1/HSP70-2)" ID="ID_236542404" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALR: 1.71-fold Down; FDR = 1.22e-08; PValue = 5.36e-10; mean CPM = 674.0; calreticulin" ID="ID_1489807244" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA8: 1.64-fold Up; FDR = 1.46e-08; PValue = 6.6e-10; mean CPM = 1881; heat shock 70kDa protein 8" ID="ID_1854454779" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA1: 15.1-fold Up; FDR = 1.9e-08; PValue = 8.86e-10; mean CPM = 3.665; HLA class II histocompatibility antigen, DQ alpha 1 chain precursor" ID="ID_1084458790" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DPB1: 7.73-fold Up; FDR = 4.73e-08; PValue = 2.45e-09; mean CPM = 1.528; Macaca mulatta major histocompatibility complex, class II, DP beta (MAMU-DPB), mRNA." ID="ID_980494714" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTSL1: 1.84-fold Up; FDR = 6.74e-08; PValue = 3.62e-09; mean CPM = 326.4; cathepsin L1" ID="ID_572853865" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RFX5: 1.45-fold Up; FDR = 2.02e-06; PValue = 1.58e-07; mean CPM = 51.69; regulatory factor X, 5 (influences HLA class II expression)" ID="ID_261905079" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90AA1: 1.41-fold Up; FDR = 4.17e-05; PValue = 4.62e-06; mean CPM = 609.6; heat shock protein 90kDa alpha (cytosolic), class A member 2" ID="ID_1232065647" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA6: 2.05-fold Down; FDR = 0.0226; PValue = 0.00604; mean CPM = 2.573; heat shock 70kDa protein 6 (HSP70B')" ID="ID_65533194" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB1: 1.21-fold Up; FDR = 0.0313; PValue = 0.00884; mean CPM = 36.07; cAMP responsive element binding protein 1" ID="ID_1702233515" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DOA: 2.74-fold Up; FDR = 0.0694; PValue = 0.0227; mean CPM = 0.9089; HLA class II histocompatibility antigen, DO alpha chain Precursor (MHC class II antigen DOA)(MHC DZ alpha)(MHC DN-alpha)" ID="ID_828344019" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDIA3: 1.17-fold Up; FDR = 0.11; PValue = 0.0393; mean CPM = 521.1; protein disulfide isomerase family A, member 3" ID="ID_1012476900" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RFXANK: 1.15-fold Up; FDR = 0.166; PValue = 0.0651; mean CPM = 33.20; regulatory factor X-associated ankyrin-containing protein" ID="ID_1720460344" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFYA: 1.14-fold Up; FDR = 0.174; PValue = 0.069; mean CPM = 34.54; nuclear transcription factor Y, alpha" ID="ID_932521791" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014796: 1.77-fold Up; FDR = 0.381; PValue = 0.182; mean CPM = 0.9085; Uncharacterized protein" ID="ID_817452135" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTSB: 1.09-fold Up; FDR = 0.489; PValue = 0.251; mean CPM = 270.7; cathepsin B" ID="ID_1375776150" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFYB: 1.1-fold Up; FDR = 0.547; PValue = 0.292; mean CPM = 15.90; nuclear transcription factor Y, beta" ID="ID_1210889527" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RFXAP: 1.18-fold Up; FDR = 0.553; PValue = 0.296; mean CPM = 3.588; regulatory factor X-associated protein" ID="ID_219214082" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90AB1: 1.07-fold Down; FDR = 0.652; PValue = 0.369; mean CPM = 905.8; heat shock protein 90kDa alpha (cytosolic), class B member 1" ID="ID_1455074902" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90AA1: 1.8-fold Up; FDR = 0.749; PValue = 0.449; mean CPM = 0.8328; heat shock protein 90kDa alpha (cytosolic), class A member 1" ID="ID_891310876" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD4: 1.27-fold Up; FDR = 0.807; PValue = 0.503; mean CPM = 1.122; CD4 molecule" ID="ID_458327331" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA6: 1.41-fold Down; FDR = 0.807; PValue = 0.504; mean CPM = 0.8019; interferon, alpha 6" ID="ID_1122267160" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA5: 1.05-fold Up; FDR = 0.851; PValue = 0.562; mean CPM = 1754; heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)" ID="ID_581811071" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA4: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 217.6; heat shock 70kDa protein 4" ID="ID_955801256" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CANX: 1.04-fold Up; FDR = 0.859; PValue = 0.573; mean CPM = 348.2; calnexin" ID="ID_678692844" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000024066: 1.25-fold Up; FDR = 0.896; PValue = 0.621; mean CPM = 0.7972; Uncharacterized protein" ID="ID_515657651" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DRB: 1.28-fold Up; FDR = 0.898; PValue = 0.624; mean CPM = 0.8112; MHC class II antigen; Uncharacterized protein" ID="ID_1208847305" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KLRC1: 1.14-fold Down; FDR = 0.903; PValue = 0.653; mean CPM = 1.817; killer cell lectin-like receptor subfamily C, member 1" ID="ID_1349062848" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA13: 1.13-fold Up; FDR = 0.908; PValue = 0.677; mean CPM = 0.7960; interferon, alpha 13" ID="ID_1613065924" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA2: 1.13-fold Up; FDR = 0.908; PValue = 0.681; mean CPM = 0.7877; HLA class II histocompatibility antigen, DQ alpha 2 chain Precursor (HLA class II histocompatibility antigen, DQ(6) alpha chain)(DX alpha chain)(HLA-DQA1)" ID="ID_1393036837" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA8: 1.13-fold Down; FDR = 0.911; PValue = 0.702; mean CPM = 0.7910; interferon, alpha 8" ID="ID_538242969" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KIR3DL2: 1.18-fold Down; FDR = 0.944; PValue = 0.764; mean CPM = 0.8149; Macaca mulatta killer immunoglobulin-like receptor KIR3DL20 (KIR3DL20), mRNA." ID="ID_816617983" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA14: 1.22-fold Up; FDR = 0.965; PValue = 0.802; mean CPM = 0.8654; interferon, alpha 14" ID="ID_1367480778" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA4: 1.28-fold Down; FDR = 0.983; PValue = 0.829; mean CPM = 0.8584; interferon, alpha 4" ID="ID_693131699" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSME3: No Change; FDR = 1; PValue = 0.946; mean CPM = 64.75; proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)" ID="ID_1645887892" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LGMN: No Change; FDR = 1; PValue = 0.967; mean CPM = 458.0; legumain" ID="ID_113832942" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD8A: No Change; FDR = 1; PValue = 0.98; mean CPM = 0.8052; CD8a molecule" ID="ID_1584018761" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA1: No Change; FDR = 1; PValue = 0.998; mean CPM = 0.8014; interferon, alpha 1" ID="ID_1892301418" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KLRD1: No Change; FDR = 1; PValue = 1; mean CPM = 0.7825; Macaca mulatta killer cell lectin-like receptor subfamily D, member 1 (KLRD1), mRNA." ID="ID_1632228685" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IFN-gamma: FDR = 3.38e-22, PValue = 1.88e-23" ID="ID_449778028" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="SP100: 3.56-fold Up; FDR = 3.74e-26; PValue = 1.58e-29; mean CPM = 187.4; SP100 nuclear antigen" ID="ID_483214507" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF1: 18.6-fold Up; FDR = 1.53e-21; PValue = 4.24e-24; mean CPM = 240.7; interferon regulatory factor 1" ID="ID_1670923881" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR3: 10.3-fold Up; FDR = 1.95e-21; PValue = 5.6e-24; mean CPM = 35.70; toll-like receptor 3" ID="ID_1030151261" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF9: 3.85-fold Up; FDR = 2.6e-19; PValue = 1.12e-21; mean CPM = 106.4; interferon regulatory factor 9" ID="ID_429127806" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_1235917278" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1698924508" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF2: 3.25-fold Up; FDR = 2.61e-18; PValue = 1.48e-20; mean CPM = 32.37; interferon regulatory factor 2" ID="ID_526932895" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF7: 14.8-fold Up; FDR = 7.66e-18; PValue = 4.82e-20; mean CPM = 11.54; Macaca mulatta interferon regulatory factor 7 (IRF7), mRNA." ID="ID_1762762143" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DMB: 17.5-fold Up; FDR = 2.77e-15; PValue = 2.66e-17; mean CPM = 9.464; HLA class II histocompatibility antigen, DM beta chain Precursor (MHC class II antigen DMB)(Really interesting new gene 7 protein)" ID="ID_632459211" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DPA1: 107-fold Up; FDR = 5.97e-15; PValue = 6.11e-17; mean CPM = 17.08; HLA class II histocompatibility antigen, DP alpha 1 chain Precursor (HLA-SB alpha chain)(MHC class II DP3-alpha)(DP(W3))(DP(W4))" ID="ID_1828161673" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DQB1: 31.1-fold Up; FDR = 6.93e-13; PValue = 1.1e-14; mean CPM = 6.675; Macaca mulatta MHC class II antigen (MAMU-DRB), mRNA." ID="ID_619035182" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD276: 1.83-fold Down; FDR = 2.04e-11; PValue = 4.56e-13; mean CPM = 65.28; CD276 molecule" ID="ID_1093533467" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PML: 2.25-fold Up; FDR = 6.36e-11; PValue = 1.6e-12; mean CPM = 94.89; Uncharacterized protein" ID="ID_157236471" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN2: 1.87-fold Up; FDR = 6.19e-10; PValue = 2e-11; mean CPM = 32.46; protein tyrosine phosphatase, non-receptor type 2" ID="ID_464470356" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPRU: 2.57-fold Down; FDR = 1.5e-09; PValue = 5.3e-11; mean CPM = 17.80; Uncharacterized protein" ID="ID_1176715193" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF8: 11.4-fold Up; FDR = 6e-09; PValue = 2.46e-10; mean CPM = 5.558; interferon regulatory factor 8" ID="ID_1946606551" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA1: 15.1-fold Up; FDR = 1.9e-08; PValue = 8.86e-10; mean CPM = 3.665; HLA class II histocompatibility antigen, DQ alpha 1 chain precursor" ID="ID_1119131832" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DPB1: 7.73-fold Up; FDR = 4.73e-08; PValue = 2.45e-09; mean CPM = 1.528; Macaca mulatta major histocompatibility complex, class II, DP beta (MAMU-DPB), mRNA." ID="ID_1299560961" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INHBA: 2.52-fold Down; FDR = 1.51e-07; PValue = 8.85e-09; mean CPM = 229.2; inhibin, beta A" ID="ID_1089889821" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CEBPG: 1.5-fold Up; FDR = 1.48e-05; PValue = 1.46e-06; mean CPM = 31.57; CCAAT/enhancer binding protein (C/EBP), gamma" ID="ID_1483787751" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS3: 1.69-fold Up; FDR = 0.000994; PValue = 0.000167; mean CPM = 37.76; suppressor of cytokine signaling 3" ID="ID_970323800" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CISH: 1.95-fold Up; FDR = 0.00116; PValue = 0.0002; mean CPM = 5.083; cytokine inducible SH2-containing protein" ID="ID_1565631255" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR1: 1.31-fold Up; FDR = 0.00151; PValue = 0.000268; mean CPM = 37.77; interferon gamma receptor 1" ID="ID_145713819" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIAS1: 1.3-fold Up; FDR = 0.00259; PValue = 0.000498; mean CPM = 29.99; protein inhibitor of activated STAT, 1" ID="ID_1985756221" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12A: 2.09-fold Up; FDR = 0.00924; PValue = 0.00215; mean CPM = 2.872; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)" ID="ID_893312738" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL18: 1.5-fold Down; FDR = 0.00981; PValue = 0.0023; mean CPM = 6.489; interleukin 18 (interferon-gamma-inducing factor)" ID="ID_383609824" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INHA: 1.73-fold Down; FDR = 0.0134; PValue = 0.00329; mean CPM = 4.332; inhibin, alpha" ID="ID_1299740859" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FCGR2B: 2.01-fold Up; FDR = 0.0231; PValue = 0.00623; mean CPM = 1.743; Uncharacterized protein" ID="ID_936539517" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR2: 1.23-fold Up; FDR = 0.0258; PValue = 0.00707; mean CPM = 46.52; interferon gamma receptor 2 (interferon gamma transducer 1)" ID="ID_1899503244" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN1: 1.2-fold Down; FDR = 0.0495; PValue = 0.0152; mean CPM = 35.05; protein tyrosine phosphatase, non-receptor type 1" ID="ID_1742960268" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DOA: 2.74-fold Up; FDR = 0.0694; PValue = 0.0227; mean CPM = 0.9089; HLA class II histocompatibility antigen, DO alpha chain Precursor (MHC class II antigen DOA)(MHC DZ alpha)(MHC DN-alpha)" ID="ID_1355834860" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_1854321344" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF4: 2.95-fold Down; FDR = 0.124; PValue = 0.0456; mean CPM = 0.9773; interferon regulatory factor 4" ID="ID_1726884981" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FCGR2A: 2.18-fold Up; FDR = 0.172; PValue = 0.0682; mean CPM = 0.9955; Fc fragment of IgG, low affinity IIa, receptor (CD32)" ID="ID_1845275574" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EBI3: 1.84-fold Up; FDR = 0.228; PValue = 0.0966; mean CPM = 1.386; Epstein-Barr virus induced 3" ID="ID_300513926" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL27: 1.82-fold Down; FDR = 0.302; PValue = 0.137; mean CPM = 0.9530; interleukin 27" ID="ID_1784717257" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014796: 1.77-fold Up; FDR = 0.381; PValue = 0.182; mean CPM = 0.9085; Uncharacterized protein" ID="ID_1672860797" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016250: 1.52-fold Up; FDR = 0.419; PValue = 0.205; mean CPM = 1.143" ID="ID_564502350" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_1014260526" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF6: 2.34-fold Down; FDR = 0.535; PValue = 0.283; mean CPM = 0.8609; interferon regulatory factor 6" ID="ID_1309445399" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCD: 1.06-fold Up; FDR = 0.696; PValue = 0.404; mean CPM = 37.45; protein kinase C, delta" ID="ID_668085651" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF9: 1.77-fold Up; FDR = 0.74; PValue = 0.441; mean CPM = 0.8485; fibroblast growth factor 9 (glia-activating factor)" ID="ID_372908822" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF5: 1.06-fold Down; FDR = 0.85; PValue = 0.561; mean CPM = 9.280; interferon regulatory factor 5" ID="ID_1412204032" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR7: 1.37-fold Down; FDR = 0.878; PValue = 0.597; mean CPM = 0.8402; toll-like receptor 7" ID="ID_1775471406" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MT2A: 1.24-fold Up; FDR = 0.893; PValue = 0.618; mean CPM = 0.9117; metallothionein 2A" ID="ID_657715029" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DRB: 1.28-fold Up; FDR = 0.898; PValue = 0.624; mean CPM = 0.8112; MHC class II antigen; Uncharacterized protein" ID="ID_545712511" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_1691227586" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTAFR: 1.39-fold Down; FDR = 0.906; PValue = 0.67; mean CPM = 0.8209; platelet-activating factor receptor" ID="ID_1639517745" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA2: 1.13-fold Up; FDR = 0.908; PValue = 0.681; mean CPM = 0.7877; HLA class II histocompatibility antigen, DQ alpha 2 chain Precursor (HLA class II histocompatibility antigen, DQ(6) alpha chain)(DX alpha chain)(HLA-DQA1)" ID="ID_952791759" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000028965: 1.11-fold Up; FDR = 0.911; PValue = 0.697; mean CPM = 1.501; Uncharacterized protein" ID="ID_803970683" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12B: 1.07-fold Up; FDR = 0.983; PValue = 0.831; mean CPM = 0.8197; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)" ID="ID_1734335866" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR9: 1.01-fold Down; FDR = 1; PValue = 0.859; mean CPM = 21.45; Macaca mulatta toll-like receptor 9 (TLR9), mRNA." ID="ID_1633928967" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="REG1A: No Change; FDR = 1; PValue = 1; mean CPM = 0.7990; regenerating islet-derived 1 alpha" ID="ID_41674082" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="REG1A: No Change; FDR = 1; PValue = 1; mean CPM = 0.7825; Uncharacterized protein" ID="ID_689413555" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000025091: No Change; FDR = 1; PValue = 1; mean CPM = 0.7808; Uncharacterized protein" ID="ID_968684313" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLA2G2A: No Change; FDR = 1; PValue = 1; mean CPM = 0.7858; phospholipase A2, group IIA (platelets, synovial fluid)" ID="ID_1348642088" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Toll-like receptor signaling: FDR = 2.06e-21, PValue = 1.52e-22" ID="ID_207259584" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TLR2: 8.94-fold Up; FDR = 6.97e-23; PValue = 1.25e-25; mean CPM = 18.41; toll-like receptor 2" ID="ID_1009357410" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL10: 462-fold Up; FDR = 1.01e-21; PValue = 2.65e-24; mean CPM = 286.2; Macaca mulatta chemokine (C-X-C motif) ligand 10 (CXCL10), mRNA." ID="ID_480355157" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR3: 10.3-fold Up; FDR = 1.95e-21; PValue = 5.6e-24; mean CPM = 35.70; toll-like receptor 3" ID="ID_455338758" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL11: 256-fold Up; FDR = 1e-19; PValue = 3.96e-22; mean CPM = 84.82; chemokine (C-X-C motif) ligand 11" ID="ID_199727892" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL9: 345-fold Up; FDR = 4.16e-19; PValue = 1.97e-21; mean CPM = 175.7; Macaca mulatta chemokine (C-X-C motif) ligand 9 (CXCL9), mRNA." ID="ID_680721101" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_69339284" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF7: 14.8-fold Up; FDR = 7.66e-18; PValue = 4.82e-20; mean CPM = 11.54; Macaca mulatta interferon regulatory factor 7 (IRF7), mRNA." ID="ID_69787418" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_1230814782" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LY96: 3.13-fold Up; FDR = 1.27e-10; PValue = 3.43e-12; mean CPM = 6.127; lymphocyte antigen 96" ID="ID_1629871876" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR4: 3.45-fold Up; FDR = 3.1e-09; PValue = 1.19e-10; mean CPM = 7.456; Macaca mulatta toll-like receptor 4 (TLR4), mRNA." ID="ID_1256145801" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_1216257340" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK4: 1.8-fold Up; FDR = 3.31e-08; PValue = 1.64e-09; mean CPM = 12.89; interleukin-1 receptor-associated kinase 4" ID="ID_1740963172" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1198278599" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL5: 6.74-fold Up; FDR = 2.65e-07; PValue = 1.64e-08; mean CPM = 30.35; chemokine (C-C motif) ligand 5" ID="ID_179461747" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1619522724" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD14: 2.75-fold Down; FDR = 6.54e-07; PValue = 4.46e-08; mean CPM = 5.195; CD14 molecule" ID="ID_223358306" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_601050444" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_804781273" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR2: 1.74-fold Up; FDR = 1.85e-06; PValue = 1.44e-07; mean CPM = 26.05; interferon (alpha, beta and omega) receptor 2" ID="ID_292162382" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1423613200" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K3: 1.45-fold Down; FDR = 7.01e-06; PValue = 6.34e-07; mean CPM = 180.1; mitogen-activated protein kinase kinase 3" ID="ID_1028266681" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1979349544" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPP1: 2.25-fold Down; FDR = 7.74e-05; PValue = 9.29e-06; mean CPM = 35.33; secreted phosphoprotein 1" ID="ID_1343218702" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP2: 1.45-fold Up; FDR = 0.000179; PValue = 2.4e-05; mean CPM = 65.31; TGF-beta activated kinase 1/MAP3K7 binding protein 2" ID="ID_1606539508" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40: 2.76-fold Up; FDR = 0.00039; PValue = 5.79e-05; mean CPM = 9.139; CD40 molecule, TNF receptor superfamily member 5" ID="ID_756152452" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TOLLIP: 1.36-fold Down; FDR = 0.000551; PValue = 8.57e-05; mean CPM = 28.79; Uncharacterized protein" ID="ID_1881634406" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTSK: 1.62-fold Down; FDR = 0.00104; PValue = 0.000176; mean CPM = 20.16; cathepsin K" ID="ID_1101236638" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBK1: 1.3-fold Up; FDR = 0.00337; PValue = 0.000674; mean CPM = 30.46; TANK-binding kinase 1" ID="ID_1071726625" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1358660856" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_1828753528" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR5: 1.86-fold Down; FDR = 0.00878; PValue = 0.00203; mean CPM = 3.008; toll-like receptor 5" ID="ID_37525718" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12A: 2.09-fold Up; FDR = 0.00924; PValue = 0.00215; mean CPM = 2.872; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)" ID="ID_104709645" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR1: 1.27-fold Up; FDR = 0.0101; PValue = 0.00237; mean CPM = 82.39; Uncharacterized protein" ID="ID_87571366" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_273727570" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL8: 2.33-fold Up; FDR = 0.0209; PValue = 0.00552; mean CPM = 2326; interleukin 8" ID="ID_1108209578" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_190358955" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_1070760812" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1262861435" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL3: 2.04-fold Down; FDR = 0.067; PValue = 0.0218; mean CPM = 3.575; chemokine (C-C motif) ligand 3" ID="ID_110965588" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K8: 1.35-fold Down; FDR = 0.0831; PValue = 0.0281; mean CPM = 8.912; mitogen-activated protein kinase kinase kinase 8" ID="ID_362333758" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FADD: 1.18-fold Down; FDR = 0.0936; PValue = 0.0324; mean CPM = 30.89; Uncharacterized protein" ID="ID_1002565941" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_71976495" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_1444602196" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1167810593" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_84882855" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_306296835" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP1: 1.12-fold Down; FDR = 0.351; PValue = 0.165; mean CPM = 17.96; TGF-beta activated kinase 1/MAP3K7 binding protein 1" ID="ID_365908650" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1150245346" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TICAM1: 1.11-fold Down; FDR = 0.398; PValue = 0.192; mean CPM = 26.73; toll-like receptor adaptor molecule 1" ID="ID_491154496" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_134150655" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_706376849" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK12: 1.19-fold Down; FDR = 0.422; PValue = 0.208; mean CPM = 6.569; mitogen-activated protein kinase 12" ID="ID_361298081" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_674230426" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_430333578" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK13: 1.22-fold Down; FDR = 0.536; PValue = 0.284; mean CPM = 3.100; mitogen-activated protein kinase 13" ID="ID_1009756330" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LBP: 1.52-fold Down; FDR = 0.591; PValue = 0.324; mean CPM = 0.8819; lipopolysaccharide binding protein" ID="ID_1905575152" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF3: 1.07-fold Up; FDR = 0.611; PValue = 0.338; mean CPM = 34.56; TNF receptor-associated factor 3" ID="ID_366403241" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_1511937818" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNB1: 1.79-fold Up; FDR = 0.731; PValue = 0.433; mean CPM = 0.8526; interferon, beta 1, fibroblast" ID="ID_360882375" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA6: 1.41-fold Down; FDR = 0.807; PValue = 0.504; mean CPM = 0.8019; interferon, alpha 6" ID="ID_1287691219" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR6: 1.07-fold Down; FDR = 0.84; PValue = 0.546; mean CPM = 7.909; toll-like receptor 6" ID="ID_1451564177" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TIRAP: 1.07-fold Up; FDR = 0.841; PValue = 0.548; mean CPM = 8.693; Macaca mulatta toll-interleukin 1 receptor (TIR) domain containing adaptor protein (TIRAP), mRNA." ID="ID_1865515523" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF5: 1.06-fold Down; FDR = 0.85; PValue = 0.561; mean CPM = 9.280; interferon regulatory factor 5" ID="ID_1145695574" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1667075558" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1570760738" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR7: 1.37-fold Down; FDR = 0.878; PValue = 0.597; mean CPM = 0.8402; toll-like receptor 7" ID="ID_688554865" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK1: 1.04-fold Down; FDR = 0.885; PValue = 0.606; mean CPM = 41.54; interleukin-1 receptor-associated kinase 1" ID="ID_993773672" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_889540254" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA13: 1.13-fold Up; FDR = 0.908; PValue = 0.677; mean CPM = 0.7960; interferon, alpha 13" ID="ID_835027441" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA8: 1.13-fold Down; FDR = 0.911; PValue = 0.702; mean CPM = 0.7910; interferon, alpha 8" ID="ID_1317485425" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKE: 1.03-fold Up; FDR = 0.929; PValue = 0.737; mean CPM = 21.61; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon" ID="ID_136857437" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA14: 1.22-fold Up; FDR = 0.965; PValue = 0.802; mean CPM = 0.8654; interferon, alpha 14" ID="ID_26744231" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_954731305" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD80: 1.08-fold Up; FDR = 0.971; PValue = 0.812; mean CPM = 1.157; CD80 molecule" ID="ID_1004322094" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_395572333" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA4: 1.28-fold Down; FDR = 0.983; PValue = 0.829; mean CPM = 0.8584; interferon, alpha 4" ID="ID_1471740712" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12B: 1.07-fold Up; FDR = 0.983; PValue = 0.831; mean CPM = 0.8197; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)" ID="ID_284475831" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_849601251" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR9: 1.01-fold Down; FDR = 1; PValue = 0.859; mean CPM = 21.45; Macaca mulatta toll-like receptor 9 (TLR9), mRNA." ID="ID_748532952" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR1: 1.02-fold Up; FDR = 1; PValue = 0.945; mean CPM = 1.221; toll-like receptor 1" ID="ID_1313447775" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD86: 1.01-fold Down; FDR = 1; PValue = 0.99; mean CPM = 0.8012; CD86 molecule" ID="ID_1146871149" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA1: No Change; FDR = 1; PValue = 0.998; mean CPM = 0.8014; interferon, alpha 1" ID="ID_519821955" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-17 : FDR = 7.82e-21, PValue = 7.24e-22" ID="ID_319185168" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CXCL10: 462-fold Up; FDR = 1.01e-21; PValue = 2.65e-24; mean CPM = 286.2; Macaca mulatta chemokine (C-X-C motif) ligand 10 (CXCL10), mRNA." ID="ID_1723902725" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL11: 256-fold Up; FDR = 1e-19; PValue = 3.96e-22; mean CPM = 84.82; chemokine (C-X-C motif) ligand 11" ID="ID_1571892858" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_1469486895" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL2: 24.6-fold Up; FDR = 1.83e-15; PValue = 1.69e-17; mean CPM = 668.2; Macaca mulatta chemokine (C-C motif) ligand 2 (CCL2), mRNA." ID="ID_1088593350" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_488072457" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1877138636" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_307706433" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17B: 4.36-fold Down; FDR = 2.84e-06; PValue = 2.29e-07; mean CPM = 1.984; interleukin 17B" ID="ID_877190370" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K3: 1.45-fold Down; FDR = 7.01e-06; PValue = 6.34e-07; mean CPM = 180.1; mitogen-activated protein kinase kinase 3" ID="ID_788490616" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_249862927" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL11: 6.86-fold Up; FDR = 2.69e-05; PValue = 2.82e-06; mean CPM = 4.204; chemokine (C-C motif) ligand 11" ID="ID_31170093" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17RD: 2.25-fold Down; FDR = 0.000136; PValue = 1.75e-05; mean CPM = 2.474; interleukin 17 receptor D" ID="ID_1839270212" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTGS2: 2.02-fold Up; FDR = 0.000254; PValue = 3.59e-05; mean CPM = 314.5; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)" ID="ID_1857939195" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF2: 1.34-fold Up; FDR = 0.000403; PValue = 6.01e-05; mean CPM = 39.83; activating transcription factor 2" ID="ID_1913423618" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL1: 2.18-fold Up; FDR = 0.00609; PValue = 0.00133; mean CPM = 45.92; chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)" ID="ID_228267624" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K14: 1.47-fold Down; FDR = 0.00704; PValue = 0.00157; mean CPM = 9.470; mitogen-activated protein kinase kinase kinase 14" ID="ID_1174569432" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1874998172" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL8: 2.33-fold Up; FDR = 0.0209; PValue = 0.00552; mean CPM = 2326; interleukin 8" ID="ID_1184672085" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17D: 1.45-fold Down; FDR = 0.0235; PValue = 0.00633; mean CPM = 5.355; interleukin 17D" ID="ID_854127993" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17RE: 2.26-fold Down; FDR = 0.0313; PValue = 0.00886; mean CPM = 1.420; interleukin 17 receptor E" ID="ID_1717265269" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1772566509" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_1405088876" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP3: 3.29-fold Down; FDR = 0.104; PValue = 0.037; mean CPM = 81.12; matrix metallopeptidase 3 (stromelysin 1, progelatinase)" ID="ID_569187776" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17RA: 1.16-fold Up; FDR = 0.121; PValue = 0.0443; mean CPM = 48.31; interleukin 17 receptor A" ID="ID_125484947" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_792152944" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1958938318" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_325402249" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_244622983" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL19: 1.65-fold Down; FDR = 0.455; PValue = 0.228; mean CPM = 0.9514; interleukin 19" ID="ID_492503381" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17RC: 1.08-fold Down; FDR = 0.572; PValue = 0.31; mean CPM = 43.18; interleukin 17 receptor C" ID="ID_1603249601" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPKAPK2: 1.06-fold Down; FDR = 0.733; PValue = 0.435; mean CPM = 82.16; mitogen-activated protein kinase-activated protein kinase 2" ID="ID_1297507226" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17RB: 1.24-fold Down; FDR = 0.752; PValue = 0.452; mean CPM = 1.299; interleukin 17 receptor B" ID="ID_175207597" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1984479073" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL25: 1.24-fold Down; FDR = 0.899; PValue = 0.631; mean CPM = 0.7976; interleukin 25" ID="ID_1305937793" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17A: 1.12-fold Up; FDR = 0.911; PValue = 0.706; mean CPM = 0.7895; interleukin 17A" ID="ID_1647750123" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOS2: 1.4-fold Down; FDR = 0.917; PValue = 0.718; mean CPM = 0.8546; nitric oxide synthase 2, inducible" ID="ID_1517062193" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17F: 1.11-fold Down; FDR = 0.948; PValue = 0.771; mean CPM = 1.150; interleukin 17F" ID="ID_360947947" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_576997148" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF3IP2: 1.01-fold Down; FDR = 1; PValue = 0.913; mean CPM = 29.19; TRAF3 interacting protein 2" ID="ID_35027317" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRP: No Change; FDR = 1; PValue = 1; mean CPM = 0.7818; Uncharacterized protein" ID="ID_1871464826" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-13: FDR = 7.69e-19, PValue = 8.54e-20" ID="ID_1818118145" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1007418349" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DMB: 17.5-fold Up; FDR = 2.77e-15; PValue = 2.66e-17; mean CPM = 9.464; HLA class II histocompatibility antigen, DM beta chain Precursor (MHC class II antigen DMB)(Really interesting new gene 7 protein)" ID="ID_1114771508" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DPA1: 107-fold Up; FDR = 5.97e-15; PValue = 6.11e-17; mean CPM = 17.08; HLA class II histocompatibility antigen, DP alpha 1 chain Precursor (HLA-SB alpha chain)(MHC class II DP3-alpha)(DP(W3))(DP(W4))" ID="ID_303980199" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DQB1: 31.1-fold Up; FDR = 6.93e-13; PValue = 1.1e-14; mean CPM = 6.675; Macaca mulatta MHC class II antigen (MAMU-DRB), mRNA." ID="ID_532909747" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_643144165" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL13RA1: 1.73-fold Up; FDR = 1.81e-09; PValue = 6.5e-11; mean CPM = 42.50; interleukin 13 receptor, alpha 1" ID="ID_838799097" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_1755818559" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRS1: 2.78-fold Up; FDR = 7.67e-09; PValue = 3.19e-10; mean CPM = 26.55; Uncharacterized protein" ID="ID_591038029" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA1: 15.1-fold Up; FDR = 1.9e-08; PValue = 8.86e-10; mean CPM = 3.665; HLA class II histocompatibility antigen, DQ alpha 1 chain precursor" ID="ID_947590628" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DPB1: 7.73-fold Up; FDR = 4.73e-08; PValue = 2.45e-09; mean CPM = 1.528; Macaca mulatta major histocompatibility complex, class II, DP beta (MAMU-DPB), mRNA." ID="ID_116658076" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1793176324" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1249486356" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CISH: 1.95-fold Up; FDR = 0.00116; PValue = 0.0002; mean CPM = 5.083; cytokine inducible SH2-containing protein" ID="ID_802552016" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK3: 2.31-fold Up; FDR = 0.00186; PValue = 0.000342; mean CPM = 2.154; Janus kinase 3" ID="ID_992242193" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYK2: 1.24-fold Down; FDR = 0.0142; PValue = 0.00354; mean CPM = 42.58; tyrosine kinase 2" ID="ID_1392058800" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB2: 1.55-fold Down; FDR = 0.0187; PValue = 0.00485; mean CPM = 34.87; Integrin beta" ID="ID_422533077" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VCAM1: 1.53-fold Up; FDR = 0.0353; PValue = 0.0102; mean CPM = 110.0; vascular cell adhesion molecule 1" ID="ID_218332244" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DOA: 2.74-fold Up; FDR = 0.0694; PValue = 0.0227; mean CPM = 0.9089; HLA class II histocompatibility antigen, DO alpha chain Precursor (MHC class II antigen DOA)(MHC DZ alpha)(MHC DN-alpha)" ID="ID_1404125180" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT6: 1.18-fold Up; FDR = 0.0727; PValue = 0.024; mean CPM = 217.5; signal transducer and activator of transcription 6, interleukin-4 induced" ID="ID_1280185662" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB1: 1.23-fold Up; FDR = 0.0759; PValue = 0.0253; mean CPM = 2700; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)" ID="ID_1091468137" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL13RA2: 2.13-fold Up; FDR = 0.0909; PValue = 0.0313; mean CPM = 1.485; Interleukin-13 receptor subunit alpha-2; Uncharacterized protein" ID="ID_803658667" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_1003005652" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS2: 1.17-fold Up; FDR = 0.1; PValue = 0.0353; mean CPM = 31.79; son of sevenless homolog 2 (Drosophila)" ID="ID_561173194" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_698111475" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_79579980" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014796: 1.77-fold Up; FDR = 0.381; PValue = 0.182; mean CPM = 0.9085; Uncharacterized protein" ID="ID_20253364" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_372396436" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_1956379318" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_453671361" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAM: 1.44-fold Down; FDR = 0.73; PValue = 0.432; mean CPM = 0.9052; integrin, alpha M (complement component 3 receptor 3 subunit)" ID="ID_1883485118" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL4R: 1.05-fold Down; FDR = 0.803; PValue = 0.499; mean CPM = 193.5; interleukin 4 receptor" ID="ID_1313621283" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FCER2: 1.41-fold Up; FDR = 0.864; PValue = 0.58; mean CPM = 0.8258; Fc fragment of IgE, low affinity II, receptor for (CD23)" ID="ID_9512848" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DRB: 1.28-fold Up; FDR = 0.898; PValue = 0.624; mean CPM = 0.8112; MHC class II antigen; Uncharacterized protein" ID="ID_1439959958" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA2: 1.13-fold Up; FDR = 0.908; PValue = 0.681; mean CPM = 0.7877; HLA class II histocompatibility antigen, DQ alpha 2 chain Precursor (HLA class II histocompatibility antigen, DQ(6) alpha chain)(DX alpha chain)(HLA-DQA1)" ID="ID_768473132" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL13: 1.05-fold Up; FDR = 0.967; PValue = 0.805; mean CPM = 0.8212; interleukin 13" ID="ID_1938581382" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="General chemokine pathways: FDR = 2.16e-18, PValue = 2.8e-19" ID="ID_1044000535" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CXCL10: 462-fold Up; FDR = 1.01e-21; PValue = 2.65e-24; mean CPM = 286.2; Macaca mulatta chemokine (C-X-C motif) ligand 10 (CXCL10), mRNA." ID="ID_887071852" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL11: 256-fold Up; FDR = 1e-19; PValue = 3.96e-22; mean CPM = 84.82; chemokine (C-X-C motif) ligand 11" ID="ID_455034101" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL9: 345-fold Up; FDR = 4.16e-19; PValue = 1.97e-21; mean CPM = 175.7; Macaca mulatta chemokine (C-X-C motif) ligand 9 (CXCL9), mRNA." ID="ID_1396499893" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT2: 2.67-fold Up; FDR = 8.02e-19; PValue = 4.03e-21; mean CPM = 185.6; signal transducer and activator of transcription 2, 113kDa" ID="ID_1845504591" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_1838690093" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1487587096" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL2: 24.6-fold Up; FDR = 1.83e-15; PValue = 1.69e-17; mean CPM = 668.2; Macaca mulatta chemokine (C-C motif) ligand 2 (CCL2), mRNA." ID="ID_1490439173" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG10: 2.27-fold Up; FDR = 1.24e-13; PValue = 1.66e-15; mean CPM = 24.29; guanine nucleotide binding protein (G protein), gamma 10" ID="ID_704657241" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC4: 7.09-fold Down; FDR = 1.82e-12; PValue = 3.1e-14; mean CPM = 6.421; SHC (Src homology 2 domain containing) family, member 4" ID="ID_1554390919" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CX3CL1: 6.16-fold Up; FDR = 5.13e-12; PValue = 1e-13; mean CPM = 14.86; chemokine (C-X3-C motif) ligand 1" ID="ID_236622109" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_544526282" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY6: 1.89-fold Down; FDR = 1.9e-10; PValue = 5.38e-12; mean CPM = 141.3; adenylate cyclase 6" ID="ID_1056327039" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL13: 12.3-fold Up; FDR = 4.33e-10; PValue = 1.35e-11; mean CPM = 3.824; chemokine (C-C motif) ligand 13" ID="ID_239807411" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNB4: 2.14-fold Up; FDR = 2.52e-09; PValue = 9.35e-11; mean CPM = 33.45; guanine nucleotide binding protein (G protein), beta polypeptide 4" ID="ID_633015307" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_988389007" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL7: 8.24-fold Up; FDR = 6.67e-09; PValue = 2.75e-10; mean CPM = 8.249; chemokine (C-C motif) ligand 7" ID="ID_111497416" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_475630768" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL16: 3.58-fold Up; FDR = 1.19e-07; PValue = 6.74e-09; mean CPM = 6.893; chemokine (C-X-C motif) ligand 16" ID="ID_1818699223" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2B: 3.54-fold Up; FDR = 1.24e-07; PValue = 7.07e-09; mean CPM = 5.971; PTK2B protein tyrosine kinase 2 beta" ID="ID_885023450" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1B: 1.55-fold Up; FDR = 2.39e-07; PValue = 1.46e-08; mean CPM = 135.3; Ras-related protein Rap-1b; Ras-related protein Rap-1b isoform 1; Uncharacterized protein" ID="ID_236009222" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL5: 6.74-fold Up; FDR = 2.65e-07; PValue = 1.64e-08; mean CPM = 30.35; chemokine (C-C motif) ligand 5" ID="ID_1073928746" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG11: 1.65-fold Up; FDR = 2.71e-07; PValue = 1.68e-08; mean CPM = 86.60; guanine nucleotide binding protein (G protein), gamma 11" ID="ID_1696949923" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1644319178" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCB1: 1.71-fold Up; FDR = 1.31e-06; PValue = 9.73e-08; mean CPM = 34.36; phospholipase C, beta 1 (phosphoinositide-specific)" ID="ID_1504059011" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1275213005" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_388975818" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_492856864" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADRBK1: 1.5-fold Down; FDR = 3.36e-06; PValue = 2.76e-07; mean CPM = 46.25; adrenergic, beta, receptor kinase 1" ID="ID_608204155" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1757976644" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL11: 6.86-fold Up; FDR = 2.69e-05; PValue = 2.82e-06; mean CPM = 4.204; chemokine (C-C motif) ligand 11" ID="ID_1130866305" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAI1: 1.47-fold Up; FDR = 5.94e-05; PValue = 6.9e-06; mean CPM = 97.19; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1" ID="ID_1106224126" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNB3: 1.91-fold Down; FDR = 0.000162; PValue = 2.14e-05; mean CPM = 7.202; guanine nucleotide binding protein (G protein), beta polypeptide 3" ID="ID_779301923" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACA: 1.36-fold Down; FDR = 0.000167; PValue = 2.22e-05; mean CPM = 37.75; protein kinase, cAMP-dependent, catalytic, alpha" ID="ID_1091580591" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCAR1: 1.36-fold Up; FDR = 0.000193; PValue = 2.61e-05; mean CPM = 210.4; breast cancer anti-estrogen resistance 1" ID="ID_1841739288" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCB4: 1.75-fold Down; FDR = 0.00025; PValue = 3.52e-05; mean CPM = 6.730; phospholipase C, beta 4" ID="ID_883391369" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASGRP2: 2.4-fold Up; FDR = 0.000359; PValue = 5.28e-05; mean CPM = 5.834; Uncharacterized protein" ID="ID_703890642" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PREX1: 1.34-fold Down; FDR = 0.000592; PValue = 9.28e-05; mean CPM = 89.02; phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1" ID="ID_1430303401" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK3: 2.31-fold Up; FDR = 0.00186; PValue = 0.000342; mean CPM = 2.154; Janus kinase 3" ID="ID_1148389466" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCR4: 4.65-fold Down; FDR = 0.00226; PValue = 0.000426; mean CPM = 2.073; chemokine (C-X-C motif) receptor 4" ID="ID_1373954692" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHOA: 1.28-fold Down; FDR = 0.00295; PValue = 0.000575; mean CPM = 277.8; ras homolog gene family, member A" ID="ID_1416389454" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKX: 1.31-fold Down; FDR = 0.00331; PValue = 0.000658; mean CPM = 24.94; protein kinase, X-linked" ID="ID_751907744" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1B: 1.43-fold Up; FDR = 0.00346; PValue = 0.000693; mean CPM = 12.81; RAP1B, member of RAS oncogene family" ID="ID_938830919" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG12: 1.31-fold Up; FDR = 0.00387; PValue = 0.000792; mean CPM = 24.97; guanine nucleotide binding protein (G protein), gamma 12" ID="ID_1074617461" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL3: 3.28-fold Up; FDR = 0.00459; PValue = 0.000963; mean CPM = 50.55; chemokine (C-X-C motif) ligand 3" ID="ID_1080105845" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV3: 1.82-fold Down; FDR = 0.00463; PValue = 0.000973; mean CPM = 7.044; vav 3 guanine nucleotide exchange factor" ID="ID_1565972397" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAI3: 1.26-fold Up; FDR = 0.00487; PValue = 0.00103; mean CPM = 113.8; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3" ID="ID_559401097" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1149591251" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR9: 3.89-fold Down; FDR = 0.00547; PValue = 0.00117; mean CPM = 0.9346; chemokine (C-C motif) receptor 9" ID="ID_1224450458" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL1: 2.18-fold Up; FDR = 0.00609; PValue = 0.00133; mean CPM = 45.92; chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)" ID="ID_1291233297" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL8: 3.3-fold Up; FDR = 0.00609; PValue = 0.00133; mean CPM = 1.313; chemokine (C-C motif) ligand 8" ID="ID_89769875" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WASL: 1.26-fold Up; FDR = 0.00781; PValue = 0.00177; mean CPM = 33.90; Wiskott-Aldrich syndrome-like" ID="ID_1193932078" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PF4V1: 2.28-fold Down; FDR = 0.00877; PValue = 0.00202; mean CPM = 3.258; platelet factor 4 variant 1" ID="ID_961295301" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY9: 1.32-fold Down; FDR = 0.00986; PValue = 0.00231; mean CPM = 84.04; adenylate cyclase 9" ID="ID_1493513336" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL20: 2.09-fold Up; FDR = 0.0108; PValue = 0.00256; mean CPM = 60.21; Macaca mulatta chemokine (C-C motif) ligand 20 (CCL20), mRNA." ID="ID_1216934403" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCZ: 1.51-fold Up; FDR = 0.0152; PValue = 0.00381; mean CPM = 10.46; protein kinase C, zeta" ID="ID_1825488490" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRK4: 1.55-fold Down; FDR = 0.0188; PValue = 0.0049; mean CPM = 5.871; G protein-coupled receptor kinase 4" ID="ID_354718796" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1716691623" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL8: 2.33-fold Up; FDR = 0.0209; PValue = 0.00552; mean CPM = 2326; interleukin 8" ID="ID_1600443978" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DOCK2: 1.4-fold Up; FDR = 0.0216; PValue = 0.00573; mean CPM = 37.89; dedicator of cytokinesis 2" ID="ID_189908395" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1793750722" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC2: 2.96-fold Up; FDR = 0.0309; PValue = 0.00872; mean CPM = 0.9737; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)" ID="ID_1515901289" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL18: 3.2-fold Down; FDR = 0.0322; PValue = 0.00915; mean CPM = 0.9111; chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)" ID="ID_1968332765" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR7: 1.48-fold Down; FDR = 0.0357; PValue = 0.0103; mean CPM = 13.37; chemokine (C-C motif) receptor 7" ID="ID_1877992383" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1940506897" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KRAS: 1.35-fold Down; FDR = 0.0401; PValue = 0.0119; mean CPM = 13.10; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog" ID="ID_1318692078" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY5: 2.17-fold Down; FDR = 0.042; PValue = 0.0125; mean CPM = 1.219; adenylate cyclase 5" ID="ID_1471701033" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY7: 1.24-fold Down; FDR = 0.0434; PValue = 0.013; mean CPM = 157.2; adenylate cyclase 7" ID="ID_1879709707" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCB2: 3.68-fold Down; FDR = 0.0481; PValue = 0.0147; mean CPM = 1.557; Uncharacterized protein" ID="ID_866554115" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NRAS: 1.2-fold Down; FDR = 0.0546; PValue = 0.017; mean CPM = 32.39; neuroblastoma RAS viral (v-ras) oncogene homolog" ID="ID_1409791971" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL28: 2.67-fold Up; FDR = 0.0616; PValue = 0.0197; mean CPM = 1.020; chemokine (C-C motif) ligand 28" ID="ID_402545573" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL3: 2.04-fold Down; FDR = 0.067; PValue = 0.0218; mean CPM = 3.575; chemokine (C-C motif) ligand 3" ID="ID_652407381" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_633694577" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TIAM1: 1.23-fold Up; FDR = 0.0747; PValue = 0.0248; mean CPM = 38.38; T-cell lymphoma invasion and metastasis 1" ID="ID_1872157525" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCR5: 2.19-fold Down; FDR = 0.0766; PValue = 0.0256; mean CPM = 1.341; chemokine (C-X-C motif) receptor 5" ID="ID_69034113" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1A: 1.17-fold Up; FDR = 0.0888; PValue = 0.0304; mean CPM = 37.16; RAP1A, member of RAS oncogene family" ID="ID_37103845" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3A: 1.18-fold Down; FDR = 0.097; PValue = 0.0338; mean CPM = 25.14; Glycogen synthase kinase-3 alpha; Uncharacterized protein" ID="ID_1105570478" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS2: 1.17-fold Up; FDR = 0.1; PValue = 0.0353; mean CPM = 31.79; son of sevenless homolog 2 (Drosophila)" ID="ID_1000107973" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARRB1: 1.35-fold Down; FDR = 0.107; PValue = 0.0382; mean CPM = 4.106; arrestin, beta 1" ID="ID_108786466" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_1071678913" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG2: 1.64-fold Up; FDR = 0.117; PValue = 0.0421; mean CPM = 2.320; guanine nucleotide binding protein (G protein), gamma 2" ID="ID_43746958" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAI2: 1.15-fold Down; FDR = 0.134; PValue = 0.0501; mean CPM = 356.3; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2" ID="ID_182268260" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_1016532870" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG3: 1.6-fold Down; FDR = 0.155; PValue = 0.0601; mean CPM = 1.706; guanine nucleotide binding protein (G protein), gamma 3" ID="ID_1013193161" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ROCK2: 1.14-fold Up; FDR = 0.166; PValue = 0.065; mean CPM = 247.7; Rho-associated, coiled-coil containing protein kinase 2" ID="ID_1076902457" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC2: 1.34-fold Down; FDR = 0.191; PValue = 0.0774; mean CPM = 7.313; SHC (Src homology 2 domain containing) transforming protein 2" ID="ID_607553349" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1156394339" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL6: 1.5-fold Down; FDR = 0.2; PValue = 0.082; mean CPM = 258.8; chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)" ID="ID_1580773388" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_126790771" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BRAF: 1.14-fold Down; FDR = 0.228; PValue = 0.0964; mean CPM = 24.98; v-raf murine sarcoma viral oncogene homolog B1" ID="ID_395380699" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_490166757" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY4: 1.24-fold Up; FDR = 0.328; PValue = 0.151; mean CPM = 8.390; adenylate cyclase 4" ID="ID_1906458127" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_229357852" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ELMO1: 1.82-fold Down; FDR = 0.348; PValue = 0.163; mean CPM = 2.504; engulfment and cell motility 1" ID="ID_1828154196" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG7: 1.75-fold Down; FDR = 0.366; PValue = 0.174; mean CPM = 0.9647; guanine nucleotide binding protein (G protein), gamma 7" ID="ID_1138967552" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRKL: 1.11-fold Up; FDR = 0.371; PValue = 0.176; mean CPM = 34.10; v-crk sarcoma virus CT10 oncogene homolog (avian)-like" ID="ID_139579069" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1976595155" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2: 1.1-fold Up; FDR = 0.394; PValue = 0.191; mean CPM = 102.5; PTK2 protein tyrosine kinase 2" ID="ID_1183058320" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL14: 1.14-fold Up; FDR = 0.405; PValue = 0.197; mean CPM = 133.7; Uncharacterized protein" ID="ID_813298154" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL26: 1.74-fold Down; FDR = 0.423; PValue = 0.208; mean CPM = 0.8756; chemokine (C-C motif) ligand 26" ID="ID_549166262" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_534642109" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR5: 1.56-fold Down; FDR = 0.487; PValue = 0.249; mean CPM = 1.064; chemokine (C-C motif) receptor 5" ID="ID_213186447" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL12: 1.27-fold Down; FDR = 0.488; PValue = 0.251; mean CPM = 4.383; chemokine (C-X-C motif) ligand 12" ID="ID_71719557" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGR: 1.63-fold Up; FDR = 0.516; PValue = 0.269; mean CPM = 1.191; Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog" ID="ID_1969339973" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG4: 1.65-fold Down; FDR = 0.524; PValue = 0.275; mean CPM = 0.8771; guanine nucleotide binding protein (G protein), gamma 4" ID="ID_708225425" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_521932412" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOXO3: 1.08-fold Down; FDR = 0.55; PValue = 0.294; mean CPM = 48.45; forkhead box O3" ID="ID_1236727130" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNB1: 1.08-fold Down; FDR = 0.565; PValue = 0.305; mean CPM = 299.4; guanine nucleotide binding protein (G protein), beta polypeptide 1" ID="ID_1978094437" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PARD3: 1.07-fold Up; FDR = 0.581; PValue = 0.316; mean CPM = 129.4; par-3 partitioning defective 3 homolog (C. elegans)" ID="ID_1576287865" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC3: 1.37-fold Down; FDR = 0.584; PValue = 0.318; mean CPM = 1.193; SHC-transforming protein 3; Uncharacterized protein" ID="ID_777609858" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDC42: 1.07-fold Down; FDR = 0.608; PValue = 0.335; mean CPM = 91.67; cell division cycle 42" ID="ID_711375488" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNGT2: 1.9-fold Up; FDR = 0.613; PValue = 0.339; mean CPM = 0.8227; guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2" ID="ID_1903112293" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000001259: 1.31-fold Down; FDR = 0.663; PValue = 0.378; mean CPM = 3.829; Uncharacterized protein" ID="ID_1168321430" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSK: 1.06-fold Down; FDR = 0.673; PValue = 0.386; mean CPM = 45.36; c-src tyrosine kinase" ID="ID_920673128" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CX3CR1: 2.01-fold Up; FDR = 0.678; PValue = 0.389; mean CPM = 0.8149; chemokine (C-X3-C motif) receptor 1" ID="ID_1733010121" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNB2: 1.06-fold Down; FDR = 0.685; PValue = 0.395; mean CPM = 129.1; guanine nucleotide binding protein (G protein), beta polypeptide 2" ID="ID_24014657" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCD: 1.06-fold Up; FDR = 0.696; PValue = 0.404; mean CPM = 37.45; protein kinase C, delta" ID="ID_1318874425" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADRBK2: 1.11-fold Down; FDR = 0.715; PValue = 0.419; mean CPM = 8.977; adrenergic, beta, receptor kinase 2" ID="ID_113717112" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCB: 1.86-fold Up; FDR = 0.727; PValue = 0.43; mean CPM = 0.8705; protein kinase C, beta" ID="ID_145218717" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG13: 1.67-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8104; guanine nucleotide binding protein (G protein), gamma 13" ID="ID_1882009935" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WAS: 1.37-fold Down; FDR = 0.771; PValue = 0.469; mean CPM = 0.9085; Wiskott-Aldrich syndrome" ID="ID_537844303" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL1: 1.56-fold Up; FDR = 0.772; PValue = 0.47; mean CPM = 0.8202; chemokine (C-C motif) ligand 1" ID="ID_1084760421" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRK: 1.05-fold Up; FDR = 0.791; PValue = 0.488; mean CPM = 59.92; v-crk sarcoma virus CT10 oncogene homolog (avian)" ID="ID_989957637" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACG: 1.51-fold Down; FDR = 0.795; PValue = 0.491; mean CPM = 0.8026; protein kinase, cAMP-dependent, catalytic, gamma" ID="ID_587175985" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HCK: 1.3-fold Down; FDR = 0.797; PValue = 0.494; mean CPM = 0.9272; Uncharacterized protein" ID="ID_323298973" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR6: 1.51-fold Down; FDR = 0.807; PValue = 0.504; mean CPM = 0.8112; Macaca mulatta chemokine (C-C motif) receptor 6 (CCR6), mRNA." ID="ID_1733234455" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL27: 1.17-fold Up; FDR = 0.817; PValue = 0.515; mean CPM = 1.645; chemokine (C-C motif) ligand 27" ID="ID_1255730520" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRK5: 1.09-fold Up; FDR = 0.82; PValue = 0.519; mean CPM = 11.78; G protein-coupled receptor kinase 5" ID="ID_790521740" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR2: 1.51-fold Up; FDR = 0.823; PValue = 0.523; mean CPM = 0.8333; chemokine (C-C motif) receptor 2" ID="ID_1871299380" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR4: 1.74-fold Up; FDR = 0.831; PValue = 0.533; mean CPM = 0.8536; chemokine (C-C motif) receptor 4" ID="ID_1585344048" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XCL1: 1.39-fold Up; FDR = 0.838; PValue = 0.544; mean CPM = 0.8038; chemokine (C motif) ligand 1" ID="ID_1856226302" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_403701155" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV1: 1.25-fold Down; FDR = 0.858; PValue = 0.572; mean CPM = 0.9515; vav 1 guanine nucleotide exchange factor" ID="ID_103486467" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY2: 1.18-fold Down; FDR = 0.864; PValue = 0.58; mean CPM = 1.755; adenylate cyclase 2 (brain)" ID="ID_527648570" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL16: 1.27-fold Up; FDR = 0.865; PValue = 0.581; mean CPM = 0.7999; chemokine (C-C motif) ligand 16" ID="ID_761207631" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY8: 1.28-fold Up; FDR = 0.891; PValue = 0.614; mean CPM = 0.8757; adenylate cyclase 8 (brain)" ID="ID_962198417" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XCL1: 1.24-fold Down; FDR = 0.899; PValue = 0.635; mean CPM = 0.7954; Macaca mulatta chemokine (C motif) ligand 1 (XCL1), mRNA." ID="ID_834415750" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XCL1: 1.24-fold Down; FDR = 0.899; PValue = 0.635; mean CPM = 0.7954; Macaca mulatta chemokine (C motif) ligand 1 (XCL1), mRNA." ID="ID_1628797295" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000021684: 1.44-fold Up; FDR = 0.903; PValue = 0.662; mean CPM = 0.8513; Uncharacterized protein" ID="ID_37459353" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR3: 1.43-fold Up; FDR = 0.906; PValue = 0.665; mean CPM = 0.8397; chemokine (C-C motif) receptor 3" ID="ID_414381859" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY1: 1.13-fold Down; FDR = 0.908; PValue = 0.682; mean CPM = 1.243; adenylate cyclase 1 (brain)" ID="ID_957100324" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL14: 1.15-fold Up; FDR = 0.909; PValue = 0.69; mean CPM = 0.7938; chemokine (C-C motif) ligand 14" ID="ID_1785664833" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACB: 1.03-fold Up; FDR = 0.911; PValue = 0.694; mean CPM = 30.10; protein kinase, cAMP-dependent, catalytic, beta" ID="ID_868692047" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK1: 1.03-fold Down; FDR = 0.911; PValue = 0.705; mean CPM = 18.65; p21 protein (Cdc42/Rac)-activated kinase 1" ID="ID_237715063" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR1: 1.24-fold Up; FDR = 0.915; PValue = 0.714; mean CPM = 0.8590; Macaca mulatta chemokine (C-C motif) receptor 1 (CCR1), mRNA." ID="ID_105061074" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_620655616" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG5: 1.02-fold Down; FDR = 0.952; PValue = 0.781; mean CPM = 21.93; guanine nucleotide binding protein (G protein), gamma 5" ID="ID_278455381" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_1552882349" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XCR1: 1.09-fold Up; FDR = 0.971; PValue = 0.812; mean CPM = 0.8071; chemokine (C motif) receptor 1" ID="ID_1567325378" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL21: 1.09-fold Down; FDR = 0.972; PValue = 0.813; mean CPM = 1.083; chemokine (C-C motif) ligand 21" ID="ID_1899264113" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRK1: 1.21-fold Up; FDR = 0.987; PValue = 0.837; mean CPM = 0.8126; G protein-coupled receptor kinase 1" ID="ID_941920107" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG8: 1.11-fold Down; FDR = 0.989; PValue = 0.84; mean CPM = 0.8494; guanine nucleotide binding protein (G protein), gamma 8" ID="ID_357368149" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR8: 1.15-fold Down; FDR = 0.999; PValue = 0.857; mean CPM = 0.8181; chemokine (C-C motif) receptor 8" ID="ID_711259870" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY3: 1.01-fold Up; FDR = 1; PValue = 0.871; mean CPM = 34.92; adenylate cyclase 3" ID="ID_1819956794" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNGT1: 1.05-fold Up; FDR = 1; PValue = 0.871; mean CPM = 0.8362; guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1" ID="ID_1735594441" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITK: 1.07-fold Up; FDR = 1; PValue = 0.871; mean CPM = 0.9033; IL2-inducible T-cell kinase" ID="ID_1038916589" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL25: 1.05-fold Down; FDR = 1; PValue = 0.872; mean CPM = 1.770; chemokine (C-C motif) ligand 25" ID="ID_705789501" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL22: 1.13-fold Down; FDR = 1; PValue = 0.872; mean CPM = 0.8179; chemokine (C-C motif) ligand 22" ID="ID_834925467" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNB5: 1.04-fold Down; FDR = 1; PValue = 0.881; mean CPM = 1.533; guanine nucleotide binding protein (G protein), beta 5" ID="ID_1601632312" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR10: 1.01-fold Down; FDR = 1; PValue = 0.929; mean CPM = 4.275; chemokine (C-C motif) receptor 10" ID="ID_390894204" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCR2: 1.14-fold Up; FDR = 1; PValue = 0.929; mean CPM = 0.8384; chemokine (C-X-C motif) receptor 2" ID="ID_373582494" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCR3: 1.03-fold Up; FDR = 1; PValue = 0.943; mean CPM = 0.9843; chemokine (C-X-C motif) receptor 3" ID="ID_1506222187" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPBP: 1.16-fold Up; FDR = 1; PValue = 0.95; mean CPM = 0.8406; pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)" ID="ID_35250455" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_24073639" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL23: 1.03-fold Down; FDR = 1; PValue = 0.963; mean CPM = 0.9423; Macaca mulatta chemokine (C-C motif) ligand 23 (CCL23), mRNA." ID="ID_877537201" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV2: No Change; FDR = 1; PValue = 0.976; mean CPM = 25.65; vav 2 guanine nucleotide exchange factor" ID="ID_200430506" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRK7: 1.04-fold Down; FDR = 1; PValue = 0.982; mean CPM = 0.8188; G protein-coupled receptor kinase 7" ID="ID_1901703269" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL17: 1.01-fold Up; FDR = 1; PValue = 0.993; mean CPM = 0.8083; Macaca mulatta chemokine (C-C motif) ligand 17 (CCL17), mRNA." ID="ID_670527894" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL24: 1.01-fold Up; FDR = 1; PValue = 0.999; mean CPM = 0.8072; Uncharacterized protein" ID="ID_1521739439" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL13: No Change; FDR = 1; PValue = 1; mean CPM = 0.7851; chemokine (C-X-C motif) ligand 13" ID="ID_1982747226" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCR1: No Change; FDR = 1; PValue = 1; mean CPM = 0.7827; chemokine (C-X-C motif) receptor 1" ID="ID_1704752785" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PF4: 1.04-fold Up; FDR = 1; PValue = 1; mean CPM = 0.8136; platelet factor 4" ID="ID_182026586" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-22: FDR = 1.03e-17, PValue = 1.52e-18" ID="ID_1465745011" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="STAT2: 2.67-fold Up; FDR = 8.02e-19; PValue = 4.03e-21; mean CPM = 185.6; signal transducer and activator of transcription 2, 113kDa" ID="ID_555559415" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_1443017326" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_934915836" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5A: 2.28-fold Up; FDR = 6.87e-14; PValue = 8.58e-16; mean CPM = 21.55; signal transducer and activator of transcription 5A" ID="ID_312863682" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_708057237" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_1935469086" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1013207979" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_923638934" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT4: 1.79-fold Up; FDR = 2.3e-05; PValue = 2.36e-06; mean CPM = 26.79; signal transducer and activator of transcription 4" ID="ID_109930493" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS3: 1.69-fold Up; FDR = 0.000994; PValue = 0.000167; mean CPM = 37.76; suppressor of cytokine signaling 3" ID="ID_1756274512" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK3: 2.31-fold Up; FDR = 0.00186; PValue = 0.000342; mean CPM = 2.154; Janus kinase 3" ID="ID_406817290" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYK2: 1.24-fold Down; FDR = 0.0142; PValue = 0.00354; mean CPM = 42.58; tyrosine kinase 2" ID="ID_1001031172" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1562090631" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1306417650" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_444349990" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_464290705" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1240636978" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1956993729" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL10RA: 1.55-fold Down; FDR = 0.516; PValue = 0.269; mean CPM = 0.9545; interleukin 10 receptor, alpha" ID="ID_1310068602" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL22RA1: 1.26-fold Up; FDR = 0.846; PValue = 0.555; mean CPM = 0.9674; interleukin 22 receptor, alpha 1" ID="ID_176309544" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL22RA2: 1.2-fold Down; FDR = 0.899; PValue = 0.629; mean CPM = 0.7954; interleukin 22 receptor, alpha 2" ID="ID_1919046223" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL22: 1.33-fold Down; FDR = 0.928; PValue = 0.735; mean CPM = 0.8193; interleukin 22" ID="ID_930794752" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="CTL mediated immune response: FDR = 1.32e-17, PValue = 2.2e-18" ID="ID_712371345" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="ICAM1: 24.6-fold Up; FDR = 2.39e-17; PValue = 1.64e-19; mean CPM = 232.4; intercellular adhesion molecule 1" ID="ID_1470426671" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB2: 1.55-fold Down; FDR = 0.0187; PValue = 0.00485; mean CPM = 34.87; Integrin beta" ID="ID_519225820" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD247: 1.43-fold Down; FDR = 0.695; PValue = 0.404; mean CPM = 0.9076; Macaca mulatta CD247 molecule (CD247), mRNA." ID="ID_1123935299" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GZMB: 1.43-fold Up; FDR = 0.83; PValue = 0.532; mean CPM = 0.7972; granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)" ID="ID_1318862346" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRF1: 1.75-fold Up; FDR = 0.841; PValue = 0.548; mean CPM = 0.8583; perforin 1 (pore forming protein)" ID="ID_1678258524" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3D: 1.22-fold Down; FDR = 0.903; PValue = 0.641; mean CPM = 0.7953; CD3d molecule, delta (CD3-TCR complex)" ID="ID_773706075" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FASLG: 1.2-fold Down; FDR = 0.941; PValue = 0.757; mean CPM = 0.8088; Fas ligand (TNF superfamily, member 6)" ID="ID_1539820763" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAL: 1.03-fold Up; FDR = 1; PValue = 0.95; mean CPM = 1.035; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)" ID="ID_1731952571" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3G: 1.03-fold Up; FDR = 1; PValue = 0.977; mean CPM = 0.8190; CD3g molecule, gamma (CD3-TCR complex)" ID="ID_676991025" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3E: 1.07-fold Down; FDR = 1; PValue = 0.981; mean CPM = 0.7994; Uncharacterized protein" ID="ID_1408459710" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-6 : FDR = 7.71e-17, PValue = 1.43e-17" ID="ID_30144729" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="IRF1: 18.6-fold Up; FDR = 1.53e-21; PValue = 4.24e-24; mean CPM = 240.7; interferon regulatory factor 1" ID="ID_1965558258" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_1715787797" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1016035966" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_1779168193" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_1003220183" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL6ST: 1.78-fold Up; FDR = 1.86e-08; PValue = 8.65e-10; mean CPM = 437.6; interleukin 6 signal transducer (gp130, oncostatin M receptor)" ID="ID_20289297" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRDM1: 3.05-fold Up; FDR = 3.55e-08; PValue = 1.78e-09; mean CPM = 8.715; PR domain containing 1, with ZNF domain" ID="ID_217121994" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_910984909" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L1: 1.51-fold Up; FDR = 9.13e-07; PValue = 6.52e-08; mean CPM = 66.15; Bcl-2-like protein 1; Bcl-2-like protein 1 isoform 1; Uncharacterized protein" ID="ID_1478090733" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_248701475" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL6R: 3.84-fold Down; FDR = 6.68e-05; PValue = 7.89e-06; mean CPM = 4.840; interleukin 6 receptor" ID="ID_45690845" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAD: 1.36-fold Down; FDR = 0.000605; PValue = 9.52e-05; mean CPM = 48.46; BCL2-associated agonist of cell death" ID="ID_55351258" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS3: 1.69-fold Up; FDR = 0.000994; PValue = 0.000167; mean CPM = 37.76; suppressor of cytokine signaling 3" ID="ID_99116983" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYK2: 1.24-fold Down; FDR = 0.0142; PValue = 0.00354; mean CPM = 42.58; tyrosine kinase 2" ID="ID_1878222658" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC1: 1.25-fold Up; FDR = 0.0159; PValue = 0.00403; mean CPM = 27.51; histone deacetylase 1" ID="ID_1297796339" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1406038903" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1176593648" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_1704553775" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCOA1: 1.18-fold Up; FDR = 0.112; PValue = 0.04; mean CPM = 20.42; nuclear receptor coactivator 1" ID="ID_1739431545" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_1051514130" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="A2M: 1.33-fold Up; FDR = 0.181; PValue = 0.0726; mean CPM = 750.0; alpha-2-macroglobulin" ID="ID_791658869" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1311292080" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_1026695659" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_841225487" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_28777405" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GAB1: 1.1-fold Up; FDR = 0.635; PValue = 0.356; mean CPM = 14.59; GRB2-associated binding protein 1" ID="ID_221915133" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCD: 1.06-fold Up; FDR = 0.696; PValue = 0.404; mean CPM = 37.45; protein kinase C, delta" ID="ID_473986904" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HCK: 1.3-fold Down; FDR = 0.797; PValue = 0.494; mean CPM = 0.9272; Uncharacterized protein" ID="ID_678184126" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV1: 1.25-fold Down; FDR = 0.858; PValue = 0.572; mean CPM = 0.9515; vav 1 guanine nucleotide exchange factor" ID="ID_1981599696" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1181311838" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB1: 1.04-fold Up; FDR = 0.88; PValue = 0.6; mean CPM = 30.80; Uncharacterized protein" ID="ID_1249677429" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_1974175977" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_1881372643" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREBBP: 1.01-fold Down; FDR = 0.993; PValue = 0.847; mean CPM = 137.7; CREB binding protein" ID="ID_1761558493" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_323646454" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLK: No Change; FDR = 1; PValue = 0.97; mean CPM = 11.78; nemo-like kinase" ID="ID_736402230" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AGT: 1.02-fold Down; FDR = 1; PValue = 0.996; mean CPM = 0.8004; angiotensinogen (serpin peptidase inhibitor, clade A, member 8)" ID="ID_919255189" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRP: No Change; FDR = 1; PValue = 1; mean CPM = 0.7818; Uncharacterized protein" ID="ID_1387597118" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-21: FDR = 1.01e-16, PValue = 2.06e-17" ID="ID_709137132" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1059782443" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_350422733" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_1766919770" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BID: 1.66-fold Up; FDR = 5.41e-09; PValue = 2.19e-10; mean CPM = 35.19; BH3 interacting domain death agonist" ID="ID_539711380" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1B: 1.64-fold Up; FDR = 1.22e-08; PValue = 5.39e-10; mean CPM = 32.96; Cyclin-dependent kinase inhibitor 1B; Uncharacterized protein" ID="ID_282880131" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRDM1: 3.05-fold Up; FDR = 3.55e-08; PValue = 1.78e-09; mean CPM = 8.715; PR domain containing 1, with ZNF domain" ID="ID_395510814" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_1419573512" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L1: 1.51-fold Up; FDR = 9.13e-07; PValue = 6.52e-08; mean CPM = 66.15; Bcl-2-like protein 1; Bcl-2-like protein 1 isoform 1; Uncharacterized protein" ID="ID_1848220025" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17B: 4.36-fold Down; FDR = 2.84e-06; PValue = 2.29e-07; mean CPM = 1.984; interleukin 17B" ID="ID_477710650" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PARP1: 1.46-fold Down; FDR = 0.00173; PValue = 0.000315; mean CPM = 46.95; poly (ADP-ribose) polymerase 1" ID="ID_1672588887" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK3: 2.31-fold Up; FDR = 0.00186; PValue = 0.000342; mean CPM = 2.154; Janus kinase 3" ID="ID_793673167" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL20: 2.09-fold Up; FDR = 0.0108; PValue = 0.00256; mean CPM = 60.21; Macaca mulatta chemokine (C-C motif) ligand 20 (CCL20), mRNA." ID="ID_1086400163" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSF2: 2.96-fold Down; FDR = 0.0174; PValue = 0.00447; mean CPM = 73.98; colony stimulating factor 2 (granulocyte-macrophage)" ID="ID_1676854530" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17D: 1.45-fold Down; FDR = 0.0235; PValue = 0.00633; mean CPM = 5.355; interleukin 17D" ID="ID_1883727649" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL18RAP: 2.95-fold Down; FDR = 0.0275; PValue = 0.00761; mean CPM = 1.220; interleukin 18 receptor accessory protein" ID="ID_949023505" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L11: 1.34-fold Up; FDR = 0.0609; PValue = 0.0195; mean CPM = 18.38; BCL2-like 11 (apoptosis facilitator)" ID="ID_1369276028" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_46976646" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1764072222" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12RB2: 1.42-fold Down; FDR = 0.299; PValue = 0.135; mean CPM = 1.728; interleukin 12 receptor, beta 2" ID="ID_1767778681" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL21R: 1.56-fold Down; FDR = 0.534; PValue = 0.282; mean CPM = 1.021; interleukin 21 receptor" ID="ID_527819647" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_1337328430" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL6: 1.06-fold Down; FDR = 0.837; PValue = 0.542; mean CPM = 64.49; B-cell CLL/lymphoma 6" ID="ID_1241066277" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_636057846" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL25: 1.24-fold Down; FDR = 0.899; PValue = 0.631; mean CPM = 0.7976; interleukin 25" ID="ID_1177591464" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17A: 1.12-fold Up; FDR = 0.911; PValue = 0.706; mean CPM = 0.7895; interleukin 17A" ID="ID_1463568171" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2RA: 1.08-fold Up; FDR = 0.945; PValue = 0.766; mean CPM = 0.8493; interleukin 2 receptor, alpha" ID="ID_1613960794" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17F: 1.11-fold Down; FDR = 0.948; PValue = 0.771; mean CPM = 1.150; interleukin 17F" ID="ID_388663331" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL21: 1.04-fold Up; FDR = 0.948; PValue = 0.773; mean CPM = 0.8164; interleukin 21" ID="ID_481448472" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBX21: 1.09-fold Up; FDR = 0.972; PValue = 0.813; mean CPM = 0.9978; T-box 21" ID="ID_436289387" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="OX40: FDR = 2.19e-15, PValue = 4.86e-16" ID="ID_1851018160" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="ENSMMUP00000027180: 6.97-fold Up; FDR = 1.24e-21; PValue = 3.39e-24; mean CPM = 285.4; Uncharacterized protein" ID="ID_924724828" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000027180: 6.97-fold Up; FDR = 1.24e-21; PValue = 3.39e-24; mean CPM = 285.4; Uncharacterized protein" ID="ID_552853540" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000005183: 4.07-fold Up; FDR = 2.87e-21; PValue = 8.51e-24; mean CPM = 164.7; Uncharacterized protein" ID="ID_1591315553" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000005183: 4.07-fold Up; FDR = 2.87e-21; PValue = 8.51e-24; mean CPM = 164.7; Uncharacterized protein" ID="ID_1872284456" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-B: 6.07-fold Up; FDR = 2.71e-19; PValue = 1.2e-21; mean CPM = 2098; Uncharacterized protein" ID="ID_1957921942" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DMB: 17.5-fold Up; FDR = 2.77e-15; PValue = 2.66e-17; mean CPM = 9.464; HLA class II histocompatibility antigen, DM beta chain Precursor (MHC class II antigen DMB)(Really interesting new gene 7 protein)" ID="ID_1673984242" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DPA1: 107-fold Up; FDR = 5.97e-15; PValue = 6.11e-17; mean CPM = 17.08; HLA class II histocompatibility antigen, DP alpha 1 chain Precursor (HLA-SB alpha chain)(MHC class II DP3-alpha)(DP(W3))(DP(W4))" ID="ID_120768099" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DQB1: 31.1-fold Up; FDR = 6.93e-13; PValue = 1.1e-14; mean CPM = 6.675; Macaca mulatta MHC class II antigen (MAMU-DRB), mRNA." ID="ID_527367148" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA1: 15.1-fold Up; FDR = 1.9e-08; PValue = 8.86e-10; mean CPM = 3.665; HLA class II histocompatibility antigen, DQ alpha 1 chain precursor" ID="ID_735186933" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DPB1: 7.73-fold Up; FDR = 4.73e-08; PValue = 2.45e-09; mean CPM = 1.528; Macaca mulatta major histocompatibility complex, class II, DP beta (MAMU-DPB), mRNA." ID="ID_139290267" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L1: 1.51-fold Up; FDR = 9.13e-07; PValue = 6.52e-08; mean CPM = 66.15; Bcl-2-like protein 1; Bcl-2-like protein 1 isoform 1; Uncharacterized protein" ID="ID_637839238" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_35622289" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF4: 2.55-fold Down; FDR = 6.64e-06; PValue = 5.95e-07; mean CPM = 4.174; tumor necrosis factor (ligand) superfamily, member 4" ID="ID_380027771" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_492876284" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1161277861" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBID: 1.47-fold Down; FDR = 0.0247; PValue = 0.0067; mean CPM = 6.446; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta" ID="ID_1887433452" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIE: 1.3-fold Down; FDR = 0.0272; PValue = 0.00752; mean CPM = 16.93; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon" ID="ID_1878665948" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1012075034" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKAP: 1.19-fold Down; FDR = 0.0434; PValue = 0.013; mean CPM = 50.22; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein" ID="ID_258536065" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DOA: 2.74-fold Up; FDR = 0.0694; PValue = 0.0227; mean CPM = 0.9089; HLA class II histocompatibility antigen, DO alpha chain Precursor (MHC class II antigen DOA)(MHC DZ alpha)(MHC DN-alpha)" ID="ID_232485006" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIZ: 1.23-fold Up; FDR = 0.0949; PValue = 0.033; mean CPM = 91.08; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta" ID="ID_786772077" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_903280687" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1066051586" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014796: 1.77-fold Up; FDR = 0.381; PValue = 0.182; mean CPM = 0.9085; Uncharacterized protein" ID="ID_1271159005" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2: 1.48-fold Up; FDR = 0.384; PValue = 0.184; mean CPM = 1.344; Uncharacterized protein" ID="ID_383717434" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF3: 1.07-fold Up; FDR = 0.611; PValue = 0.338; mean CPM = 34.56; TNF receptor-associated factor 3" ID="ID_552208981" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD247: 1.43-fold Down; FDR = 0.695; PValue = 0.404; mean CPM = 0.9076; Macaca mulatta CD247 molecule (CD247), mRNA." ID="ID_282830492" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF4: 1.36-fold Down; FDR = 0.743; PValue = 0.444; mean CPM = 0.8892; tumor necrosis factor receptor superfamily, member 4" ID="ID_985575376" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD4: 1.27-fold Up; FDR = 0.807; PValue = 0.503; mean CPM = 1.122; CD4 molecule" ID="ID_452340278" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DRB: 1.28-fold Up; FDR = 0.898; PValue = 0.624; mean CPM = 0.8112; MHC class II antigen; Uncharacterized protein" ID="ID_1224163022" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3D: 1.22-fold Down; FDR = 0.903; PValue = 0.641; mean CPM = 0.7953; CD3d molecule, delta (CD3-TCR complex)" ID="ID_606831565" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA2: 1.13-fold Up; FDR = 0.908; PValue = 0.681; mean CPM = 0.7877; HLA class II histocompatibility antigen, DQ alpha 2 chain Precursor (HLA class II histocompatibility antigen, DQ(6) alpha chain)(DX alpha chain)(HLA-DQA1)" ID="ID_1380913222" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKE: 1.03-fold Up; FDR = 0.929; PValue = 0.737; mean CPM = 21.61; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon" ID="ID_1764656525" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_447257070" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3G: 1.03-fold Up; FDR = 1; PValue = 0.977; mean CPM = 0.8190; CD3g molecule, gamma (CD3-TCR complex)" ID="ID_1098884802" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3E: 1.07-fold Down; FDR = 1; PValue = 0.981; mean CPM = 0.7994; Uncharacterized protein" ID="ID_42749188" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2: 1.03-fold Up; FDR = 1; PValue = 0.998; mean CPM = 0.7974; interleukin 2" ID="ID_1855715094" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="NLR signaling: FDR = 2.85e-14, PValue = 6.86e-15" ID="ID_783020197" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CASP5: 68-fold Up; FDR = 3.54e-19; PValue = 1.64e-21; mean CPM = 7.240; caspase 5, apoptosis-related cysteine peptidase" ID="ID_520978713" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_1249896265" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK2: 3.75-fold Up; FDR = 6.1e-16; PValue = 5.38e-18; mean CPM = 68.21; receptor-interacting serine-threonine kinase 2" ID="ID_1794833636" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL2: 24.6-fold Up; FDR = 1.83e-15; PValue = 1.69e-17; mean CPM = 668.2; Macaca mulatta chemokine (C-C motif) ligand 2 (CCL2), mRNA." ID="ID_1648382402" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CARD6: 2.33-fold Up; FDR = 1.15e-12; PValue = 1.89e-14; mean CPM = 30.09; caspase recruitment domain family, member 6" ID="ID_308969724" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CARD8: 2.48-fold Up; FDR = 2.44e-11; PValue = 5.59e-13; mean CPM = 14.84; caspase recruitment domain family, member 8" ID="ID_1631908862" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC2: 1.96-fold Up; FDR = 1.01e-10; PValue = 2.62e-12; mean CPM = 53.58; baculoviral IAP repeat-containing 2" ID="ID_1127723234" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL13: 12.3-fold Up; FDR = 4.33e-10; PValue = 1.35e-11; mean CPM = 3.824; chemokine (C-C motif) ligand 13" ID="ID_1855575328" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CARD8: 2.02-fold Up; FDR = 1.41e-09; PValue = 4.93e-11; mean CPM = 15.89; caspase recruitment domain family, member 8" ID="ID_1635540106" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL7: 8.24-fold Up; FDR = 6.67e-09; PValue = 2.75e-10; mean CPM = 8.249; chemokine (C-C motif) ligand 7" ID="ID_248515925" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1231116746" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLRC4: 6.6-fold Up; FDR = 8.52e-08; PValue = 4.67e-09; mean CPM = 3.347; NLR family, CARD domain containing 4" ID="ID_587246179" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL5: 6.74-fold Up; FDR = 2.65e-07; PValue = 1.64e-08; mean CPM = 30.35; chemokine (C-C motif) ligand 5" ID="ID_157124309" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC3: 2.79-fold Up; FDR = 1.74e-06; PValue = 1.32e-07; mean CPM = 95.34; baculoviral IAP repeat-containing 3" ID="ID_1602111012" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_376529461" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL11: 6.86-fold Up; FDR = 2.69e-05; PValue = 2.82e-06; mean CPM = 4.204; chemokine (C-C motif) ligand 11" ID="ID_790800152" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFAIP3: 1.79-fold Up; FDR = 3.14e-05; PValue = 3.34e-06; mean CPM = 52.47; tumor necrosis factor, alpha-induced protein 3" ID="ID_1020900460" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90AA1: 1.41-fold Up; FDR = 4.17e-05; PValue = 4.62e-06; mean CPM = 609.6; heat shock protein 90kDa alpha (cytosolic), class A member 2" ID="ID_684673260" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CARD9: 1.53-fold Up; FDR = 9.57e-05; PValue = 1.18e-05; mean CPM = 16.72; caspase recruitment domain family, member 9" ID="ID_1873414036" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP2: 1.45-fold Up; FDR = 0.000179; PValue = 2.4e-05; mean CPM = 65.31; TGF-beta activated kinase 1/MAP3K7 binding protein 2" ID="ID_139232981" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOD1: 1.63-fold Up; FDR = 0.000193; PValue = 2.61e-05; mean CPM = 58.36; nucleotide-binding oligomerization domain containing 1" ID="ID_1717698678" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SUGT1: 1.35-fold Up; FDR = 0.000193; PValue = 2.61e-05; mean CPM = 54.75; SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)" ID="ID_535785345" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP3: 1.5-fold Up; FDR = 0.000276; PValue = 3.92e-05; mean CPM = 11.67; TGF-beta activated kinase 1/MAP3K7 binding protein 3" ID="ID_1380659818" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_710633819" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90B1: 1.28-fold Down; FDR = 0.00538; PValue = 0.00115; mean CPM = 1017; heat shock protein 90kDa beta (Grp94), member 1" ID="ID_1108485611" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_129734881" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL1: 2.18-fold Up; FDR = 0.00609; PValue = 0.00133; mean CPM = 45.92; chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)" ID="ID_576982551" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL8: 3.3-fold Up; FDR = 0.00609; PValue = 0.00133; mean CPM = 1.313; chemokine (C-C motif) ligand 8" ID="ID_1463718529" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL18: 1.5-fold Down; FDR = 0.00981; PValue = 0.0023; mean CPM = 6.489; interleukin 18 (interferon-gamma-inducing factor)" ID="ID_1961080320" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1858297227" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL8: 2.33-fold Up; FDR = 0.0209; PValue = 0.00552; mean CPM = 2326; interleukin 8" ID="ID_1639284654" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_468885550" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_843350248" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_1017212263" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XIAP: 1.17-fold Up; FDR = 0.177; PValue = 0.0706; mean CPM = 19.21; X-linked inhibitor of apoptosis" ID="ID_877047697" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PYCARD: 1.38-fold Down; FDR = 0.241; PValue = 0.103; mean CPM = 3.110; PYD and CARD domain containing" ID="ID_1844059270" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLRP3: 1.84-fold Down; FDR = 0.32; PValue = 0.147; mean CPM = 0.9630; NLR family, pyrin domain containing 3" ID="ID_1835956046" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP1: 1.12-fold Down; FDR = 0.351; PValue = 0.165; mean CPM = 17.96; TGF-beta activated kinase 1/MAP3K7 binding protein 1" ID="ID_1050976064" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_231078609" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_486706447" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK12: 1.19-fold Down; FDR = 0.422; PValue = 0.208; mean CPM = 6.569; mitogen-activated protein kinase 12" ID="ID_1086810506" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_732833129" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK13: 1.22-fold Down; FDR = 0.536; PValue = 0.284; mean CPM = 3.100; mitogen-activated protein kinase 13" ID="ID_175600830" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90AB1: 1.07-fold Down; FDR = 0.652; PValue = 0.369; mean CPM = 905.8; heat shock protein 90kDa alpha (cytosolic), class B member 1" ID="ID_1006370051" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_1587165952" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90AA1: 1.8-fold Up; FDR = 0.749; PValue = 0.449; mean CPM = 0.8328; heat shock protein 90kDa alpha (cytosolic), class A member 1" ID="ID_1212000161" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MEFV: 1.13-fold Up; FDR = 0.813; PValue = 0.51; mean CPM = 6.740; Mediterranean fever" ID="ID_380590028" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1406297589" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOD2: 1.17-fold Up; FDR = 0.866; PValue = 0.583; mean CPM = 1.911; nucleotide-binding oligomerization domain containing 2" ID="ID_813586665" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_1302137422" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_127187152" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRIP6: 1.01-fold Down; FDR = 1; PValue = 0.92; mean CPM = 125.6; thyroid hormone receptor interactor 6" ID="ID_1807878066" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSTPIP1: 1.03-fold Down; FDR = 1; PValue = 0.929; mean CPM = 1.615; proline-serine-threonine phosphatase interacting protein 1" ID="ID_182294843" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_781814074" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="NF-kappaB pathway: FDR = 3.87e-14, PValue = 1e-14" ID="ID_1450509692" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TLR2: 8.94-fold Up; FDR = 6.97e-23; PValue = 1.25e-25; mean CPM = 18.41; toll-like receptor 2" ID="ID_488301349" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR3: 10.3-fold Up; FDR = 1.95e-21; PValue = 5.6e-24; mean CPM = 35.70; toll-like receptor 3" ID="ID_1357091182" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1400796116" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICAM1: 24.6-fold Up; FDR = 2.39e-17; PValue = 1.64e-19; mean CPM = 232.4; intercellular adhesion molecule 1" ID="ID_888530928" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_369278611" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF10: 44.5-fold Up; FDR = 2.83e-16; PValue = 2.4e-18; mean CPM = 6.029; Tumor necrosis factor ligand superfamily member 10 isoform 1; Uncharacterized protein" ID="ID_1570051845" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL2: 24.6-fold Up; FDR = 1.83e-15; PValue = 1.69e-17; mean CPM = 668.2; Macaca mulatta chemokine (C-C motif) ligand 2 (CCL2), mRNA." ID="ID_659977920" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC2: 1.96-fold Up; FDR = 1.01e-10; PValue = 2.62e-12; mean CPM = 53.58; baculoviral IAP repeat-containing 2" ID="ID_562358210" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR4: 3.45-fold Up; FDR = 3.1e-09; PValue = 1.19e-10; mean CPM = 7.456; Macaca mulatta toll-like receptor 4 (TLR4), mRNA." ID="ID_1098678126" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_178478440" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1177680443" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF1: 1.51-fold Up; FDR = 5.28e-06; PValue = 4.58e-07; mean CPM = 22.13; activating transcription factor 1" ID="ID_1238948125" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL10: 1.55-fold Up; FDR = 5.92e-06; PValue = 5.22e-07; mean CPM = 21.83; B-cell CLL/lymphoma 10" ID="ID_1907689431" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFAIP3: 1.79-fold Up; FDR = 3.14e-05; PValue = 3.34e-06; mean CPM = 52.47; tumor necrosis factor, alpha-induced protein 3" ID="ID_983162576" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1R1: 1.6-fold Up; FDR = 3.35e-05; PValue = 3.61e-06; mean CPM = 123.7; interleukin 1 receptor, type I" ID="ID_756333862" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HMOX1: 1.94-fold Up; FDR = 7.83e-05; PValue = 9.42e-06; mean CPM = 15.01; heme oxygenase (decycling) 1" ID="ID_94362629" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_385131099" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GJA1: 1.71-fold Up; FDR = 0.000117; PValue = 1.47e-05; mean CPM = 2600; gap junction protein, alpha 1, 43kDa" ID="ID_1627248305" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOD1: 1.63-fold Up; FDR = 0.000193; PValue = 2.61e-05; mean CPM = 58.36; nucleotide-binding oligomerization domain containing 1" ID="ID_455003576" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40: 2.76-fold Up; FDR = 0.00039; PValue = 5.79e-05; mean CPM = 9.139; CD40 molecule, TNF receptor superfamily member 5" ID="ID_877666665" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_1555271999" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRIM13: 1.38-fold Up; FDR = 0.0009; PValue = 0.000149; mean CPM = 19.75; tripartite motif-containing 13" ID="ID_1313204389" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPM1A: 1.31-fold Up; FDR = 0.00101; PValue = 0.00017; mean CPM = 60.08; protein phosphatase, Mg2+/Mn2+ dependent, 1A" ID="ID_62074416" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC44A2: 1.31-fold Down; FDR = 0.00108; PValue = 0.000185; mean CPM = 154.3; solute carrier family 44, member 2" ID="ID_433244725" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="REL: 1.46-fold Down; FDR = 0.00272; PValue = 0.000526; mean CPM = 10.17; v-rel avian reticuloendotheliosis viral oncogene homolog" ID="ID_22588699" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHOA: 1.28-fold Down; FDR = 0.00295; PValue = 0.000575; mean CPM = 277.8; ras homolog gene family, member A" ID="ID_490859597" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBK1: 1.3-fold Up; FDR = 0.00337; PValue = 0.000674; mean CPM = 30.46; TANK-binding kinase 1" ID="ID_217488326" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL20: 2.09-fold Up; FDR = 0.0108; PValue = 0.00256; mean CPM = 60.21; Macaca mulatta chemokine (C-C motif) ligand 20 (CCL20), mRNA." ID="ID_1278549548" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSF2: 2.96-fold Down; FDR = 0.0174; PValue = 0.00447; mean CPM = 73.98; colony stimulating factor 2 (granulocyte-macrophage)" ID="ID_1913264489" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HTR2B: 1.75-fold Up; FDR = 0.0194; PValue = 0.0051; mean CPM = 14.36; 5-hydroxytryptamine (serotonin) receptor 2B" ID="ID_961913858" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL8: 2.33-fold Up; FDR = 0.0209; PValue = 0.00552; mean CPM = 2326; interleukin 8" ID="ID_1154688752" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1157956556" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_65931792" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRADD: 1.22-fold Up; FDR = 0.0319; PValue = 0.00907; mean CPM = 34.75; TNFRSF1A-associated via death domain" ID="ID_1258773330" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1162469419" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL3: 1.25-fold Up; FDR = 0.0559; PValue = 0.0175; mean CPM = 16.96; B-cell CLL/lymphoma 3" ID="ID_1196608319" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELB: 1.22-fold Down; FDR = 0.0606; PValue = 0.0193; mean CPM = 26.64; v-rel reticuloendotheliosis viral oncogene homolog B" ID="ID_1726335254" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSF3: 2.55-fold Up; FDR = 0.0701; PValue = 0.023; mean CPM = 72.12; colony stimulating factor 3 (granulocyte)" ID="ID_886521805" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FADD: 1.18-fold Down; FDR = 0.0936; PValue = 0.0324; mean CPM = 30.89; Uncharacterized protein" ID="ID_1545675252" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_1362918701" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1672357235" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC20A1: 1.18-fold Up; FDR = 0.244; PValue = 0.105; mean CPM = 117.7; solute carrier family 20 (phosphate transporter), member 1" ID="ID_1882668139" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK2: 1.27-fold Down; FDR = 0.259; PValue = 0.113; mean CPM = 10.13; interleukin-1 receptor-associated kinase 2" ID="ID_21379311" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1A: 1.11-fold Up; FDR = 0.297; PValue = 0.134; mean CPM = 134.7; tumor necrosis factor receptor superfamily, member 1A" ID="ID_1005124922" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1A: 1.5-fold Up; FDR = 0.315; PValue = 0.144; mean CPM = 155.4; interleukin 1, alpha" ID="ID_792640768" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGR1: 1.19-fold Down; FDR = 0.321; PValue = 0.147; mean CPM = 90.45; Early growth response protein 1; Uncharacterized protein" ID="ID_816112029" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF10B: 1.13-fold Down; FDR = 0.343; PValue = 0.16; mean CPM = 40.59; tumor necrosis factor receptor superfamily, member 10b" ID="ID_612772907" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MALT1: 1.11-fold Down; FDR = 0.35; PValue = 0.164; mean CPM = 42.89; mucosa associated lymphoid tissue lymphoma translocation gene 1" ID="ID_804821539" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TICAM1: 1.11-fold Down; FDR = 0.398; PValue = 0.192; mean CPM = 26.73; toll-like receptor adaptor molecule 1" ID="ID_69645198" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="F2R: 1.1-fold Up; FDR = 0.458; PValue = 0.23; mean CPM = 35.05; coagulation factor II (thrombin) receptor" ID="ID_1563788271" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD27: 1.52-fold Down; FDR = 0.547; PValue = 0.292; mean CPM = 1.004; CD27 molecule" ID="ID_41650045" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000000985: 1.2-fold Up; FDR = 0.569; PValue = 0.307; mean CPM = 11.32; Uncharacterized protein" ID="ID_15746416" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_247236884" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LTBR: 1.06-fold Down; FDR = 0.683; PValue = 0.394; mean CPM = 91.13; lymphotoxin beta receptor (TNFR superfamily, member 3)" ID="ID_1836931926" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNB1: 1.79-fold Up; FDR = 0.731; PValue = 0.433; mean CPM = 0.8526; interferon, beta 1, fibroblast" ID="ID_1565207049" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF10A: 1.06-fold Down; FDR = 0.732; PValue = 0.434; mean CPM = 42.75; tumor necrosis factor receptor superfamily, member 10a" ID="ID_318655703" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMED4: 1.06-fold Down; FDR = 0.74; PValue = 0.441; mean CPM = 69.78; transmembrane emp24 protein transport domain containing 4" ID="ID_1801445632" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR6: 1.07-fold Down; FDR = 0.84; PValue = 0.546; mean CPM = 7.909; toll-like receptor 6" ID="ID_540871964" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1042823903" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR7: 1.37-fold Down; FDR = 0.878; PValue = 0.597; mean CPM = 0.8402; toll-like receptor 7" ID="ID_1330319149" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK1: 1.04-fold Down; FDR = 0.885; PValue = 0.606; mean CPM = 41.54; interleukin-1 receptor-associated kinase 1" ID="ID_1374104750" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_548898241" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_561366793" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF14: 1.16-fold Down; FDR = 0.903; PValue = 0.645; mean CPM = 0.7940; tumor necrosis factor (ligand) superfamily, member 14" ID="ID_1941981942" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKE: 1.03-fold Up; FDR = 0.929; PValue = 0.737; mean CPM = 21.61; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon" ID="ID_1870253404" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FASLG: 1.2-fold Down; FDR = 0.941; PValue = 0.757; mean CPM = 0.8088; Fas ligand (TNF superfamily, member 6)" ID="ID_1399628291" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_75834615" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR9: 1.01-fold Down; FDR = 1; PValue = 0.859; mean CPM = 21.45; Macaca mulatta toll-like receptor 9 (TLR9), mRNA." ID="ID_577392352" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EDARADD: 1.04-fold Up; FDR = 1; PValue = 0.885; mean CPM = 1.496; EDAR-associated death domain" ID="ID_385031935" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR1: 1.02-fold Up; FDR = 1; PValue = 0.945; mean CPM = 1.221; toll-like receptor 1" ID="ID_738157963" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL10: 1.21-fold Down; FDR = 1; PValue = 0.964; mean CPM = 0.8614; interleukin 10" ID="ID_538252118" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AGT: 1.02-fold Down; FDR = 1; PValue = 0.996; mean CPM = 0.8004; angiotensinogen (serpin peptidase inhibitor, clade A, member 8)" ID="ID_1927266163" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA1: No Change; FDR = 1; PValue = 0.998; mean CPM = 0.8014; interferon, alpha 1" ID="ID_1149120389" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="CTLA4: FDR = 4.01e-14, PValue = 1.11e-14" ID="ID_1262372344" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_864460239" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DMB: 17.5-fold Up; FDR = 2.77e-15; PValue = 2.66e-17; mean CPM = 9.464; HLA class II histocompatibility antigen, DM beta chain Precursor (MHC class II antigen DMB)(Really interesting new gene 7 protein)" ID="ID_460047019" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DPA1: 107-fold Up; FDR = 5.97e-15; PValue = 6.11e-17; mean CPM = 17.08; HLA class II histocompatibility antigen, DP alpha 1 chain Precursor (HLA-SB alpha chain)(MHC class II DP3-alpha)(DP(W3))(DP(W4))" ID="ID_1692609384" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DQB1: 31.1-fold Up; FDR = 6.93e-13; PValue = 1.1e-14; mean CPM = 6.675; Macaca mulatta MHC class II antigen (MAMU-DRB), mRNA." ID="ID_803891679" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA1: 15.1-fold Up; FDR = 1.9e-08; PValue = 8.86e-10; mean CPM = 3.665; HLA class II histocompatibility antigen, DQ alpha 1 chain precursor" ID="ID_693749128" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DPB1: 7.73-fold Up; FDR = 4.73e-08; PValue = 2.45e-09; mean CPM = 1.528; Macaca mulatta major histocompatibility complex, class II, DP beta (MAMU-DPB), mRNA." ID="ID_978360082" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1192512561" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_35017539" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG1: 1.31-fold Down; FDR = 0.00352; PValue = 0.000707; mean CPM = 53.66; phospholipase C, gamma 1" ID="ID_382065448" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AP2B1: 1.25-fold Up; FDR = 0.00795; PValue = 0.0018; mean CPM = 199.8; adaptor-related protein complex 2, beta 1 subunit" ID="ID_96203704" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FYN: 1.22-fold Up; FDR = 0.0156; PValue = 0.00393; mean CPM = 92.94; FYN oncogene related to SRC, FGR, YES" ID="ID_973764717" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1624305052" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DOA: 2.74-fold Up; FDR = 0.0694; PValue = 0.0227; mean CPM = 0.9089; HLA class II histocompatibility antigen, DO alpha chain Precursor (MHC class II antigen DOA)(MHC DZ alpha)(MHC DN-alpha)" ID="ID_1240337261" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_157671616" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_384760458" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN22: 1.76-fold Down; FDR = 0.209; PValue = 0.0864; mean CPM = 1.477; protein tyrosine phosphatase, non-receptor type 22 (lymphoid)" ID="ID_161077326" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AP2S1: 1.13-fold Down; FDR = 0.213; PValue = 0.0887; mean CPM = 107.4; adaptor-related protein complex 2, sigma 1 subunit" ID="ID_313520725" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAT: 1.44-fold Down; FDR = 0.234; PValue = 0.0996; mean CPM = 1.871; linker for activation of T cells" ID="ID_738587346" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_944371184" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AP2A2: 1.11-fold Down; FDR = 0.296; PValue = 0.133; mean CPM = 69.59; adaptor-related protein complex 2, alpha 2 subunit" ID="ID_846457252" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_1069484839" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014796: 1.77-fold Up; FDR = 0.381; PValue = 0.182; mean CPM = 0.9085; Uncharacterized protein" ID="ID_758360220" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1359057445" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_726250701" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LCP2: 1.4-fold Up; FDR = 0.496; PValue = 0.256; mean CPM = 1.322; Uncharacterized protein" ID="ID_1529822188" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_205756798" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD247: 1.43-fold Down; FDR = 0.695; PValue = 0.404; mean CPM = 0.9076; Macaca mulatta CD247 molecule (CD247), mRNA." ID="ID_158690667" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRAP2: 1.31-fold Up; FDR = 0.701; PValue = 0.408; mean CPM = 3.696; GRB2-related adaptor protein 2" ID="ID_924550971" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD4: 1.27-fold Up; FDR = 0.807; PValue = 0.503; mean CPM = 1.122; CD4 molecule" ID="ID_1878342619" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTLA4: 1.41-fold Down; FDR = 0.827; PValue = 0.527; mean CPM = 0.8017; cytotoxic T-lymphocyte-associated protein 4" ID="ID_932226665" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZAP70: 1.25-fold Down; FDR = 0.872; PValue = 0.59; mean CPM = 0.8996; zeta-chain (TCR) associated protein kinase 70kDa" ID="ID_1415695890" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DRB: 1.28-fold Up; FDR = 0.898; PValue = 0.624; mean CPM = 0.8112; MHC class II antigen; Uncharacterized protein" ID="ID_1020220794" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3D: 1.22-fold Down; FDR = 0.903; PValue = 0.641; mean CPM = 0.7953; CD3d molecule, delta (CD3-TCR complex)" ID="ID_1368811270" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA2: 1.13-fold Up; FDR = 0.908; PValue = 0.681; mean CPM = 0.7877; HLA class II histocompatibility antigen, DQ alpha 2 chain Precursor (HLA class II histocompatibility antigen, DQ(6) alpha chain)(DX alpha chain)(HLA-DQA1)" ID="ID_775118005" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICOSLG: 1.07-fold Down; FDR = 0.909; PValue = 0.684; mean CPM = 6.739; inducible T-cell co-stimulator ligand" ID="ID_302503627" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAT1: 1.13-fold Down; FDR = 0.911; PValue = 0.702; mean CPM = 0.7899; T cell receptor associated transmembrane adaptor 1" ID="ID_261817936" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICOS: 1.19-fold Up; FDR = 0.931; PValue = 0.741; mean CPM = 0.8158; Uncharacterized protein" ID="ID_593733624" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R4: 1.02-fold Down; FDR = 0.943; PValue = 0.763; mean CPM = 93.45; protein phosphatase 2A activator, regulatory subunit 4" ID="ID_8580023" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD80: 1.08-fold Up; FDR = 0.971; PValue = 0.812; mean CPM = 1.157; CD80 molecule" ID="ID_1509806736" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITK: 1.07-fold Up; FDR = 1; PValue = 0.871; mean CPM = 0.9033; IL2-inducible T-cell kinase" ID="ID_58199438" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3G: 1.03-fold Up; FDR = 1; PValue = 0.977; mean CPM = 0.8190; CD3g molecule, gamma (CD3-TCR complex)" ID="ID_727332260" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SYK: 1.11-fold Up; FDR = 1; PValue = 0.977; mean CPM = 0.8420; spleen tyrosine kinase" ID="ID_642363788" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3E: 1.07-fold Down; FDR = 1; PValue = 0.981; mean CPM = 0.7994; Uncharacterized protein" ID="ID_1720557042" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD86: 1.01-fold Down; FDR = 1; PValue = 0.99; mean CPM = 0.8012; CD86 molecule" ID="ID_713945078" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2: 1.03-fold Up; FDR = 1; PValue = 0.998; mean CPM = 0.7974; interleukin 2" ID="ID_851048973" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-4 : FDR = 4.97e-14, PValue = 1.47e-14" ID="ID_1482455574" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_1999049614" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1651563462" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5A: 2.28-fold Up; FDR = 6.87e-14; PValue = 8.58e-16; mean CPM = 21.55; signal transducer and activator of transcription 5A" ID="ID_837845256" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_754742165" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_1909427614" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRS1: 2.78-fold Up; FDR = 7.67e-09; PValue = 3.19e-10; mean CPM = 26.55; Uncharacterized protein" ID="ID_1302134757" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_556060953" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1955959517" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_532065963" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_725085097" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS5: 1.38-fold Up; FDR = 4.45e-05; PValue = 4.96e-06; mean CPM = 88.27; suppressor of cytokine signaling 5" ID="ID_198488187" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF2: 1.34-fold Up; FDR = 0.000403; PValue = 6.01e-05; mean CPM = 39.83; activating transcription factor 2" ID="ID_965525817" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAD: 1.36-fold Down; FDR = 0.000605; PValue = 9.52e-05; mean CPM = 48.46; BCL2-associated agonist of cell death" ID="ID_640271200" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GATA3: 2.81-fold Up; FDR = 0.000734; PValue = 0.000119; mean CPM = 2.229; GATA binding protein 3" ID="ID_1244389699" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS3: 1.69-fold Up; FDR = 0.000994; PValue = 0.000167; mean CPM = 37.76; suppressor of cytokine signaling 3" ID="ID_87685180" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFIL3: 1.37-fold Up; FDR = 0.00114; PValue = 0.000196; mean CPM = 50.42; nuclear factor, interleukin 3 regulated" ID="ID_1310863227" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK3: 2.31-fold Up; FDR = 0.00186; PValue = 0.000342; mean CPM = 2.154; Janus kinase 3" ID="ID_1103471816" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GAB2: 1.33-fold Down; FDR = 0.00208; PValue = 0.000387; mean CPM = 22.59; GRB2-associated binding protein 2" ID="ID_347518852" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_695647488" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FES: 1.34-fold Up; FDR = 0.00677; PValue = 0.0015; mean CPM = 22.71; feline sarcoma oncogene" ID="ID_1455454172" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYK2: 1.24-fold Down; FDR = 0.0142; PValue = 0.00354; mean CPM = 42.58; tyrosine kinase 2" ID="ID_1198590198" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_827104192" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DOK2: 1.76-fold Down; FDR = 0.0214; PValue = 0.00569; mean CPM = 2.236; docking protein 2, 56kDa" ID="ID_982540797" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1790155822" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INPP5D: 1.88-fold Down; FDR = 0.0276; PValue = 0.00763; mean CPM = 5.690; inositol polyphosphate-5-phosphatase, 145kDa" ID="ID_1830827720" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_820875015" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1337333099" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT6: 1.18-fold Up; FDR = 0.0727; PValue = 0.024; mean CPM = 217.5; signal transducer and activator of transcription 6, interleukin-4 induced" ID="ID_1071948198" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_1884604337" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_1142411437" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC5: 1.51-fold Down; FDR = 0.134; PValue = 0.0501; mean CPM = 18.55; Baculoviral IAP repeat-containing protein 5 isoform 1; Uncharacterized protein" ID="ID_1698727238" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_154660967" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_1263747276" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EP300: 1.11-fold Up; FDR = 0.312; PValue = 0.142; mean CPM = 162.8; E1A binding protein p300" ID="ID_1481595552" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_196698547" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1447360520" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_915493019" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_972133916" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRH1: 1.25-fold Up; FDR = 0.455; PValue = 0.228; mean CPM = 4.779; histamine receptor H1" ID="ID_1749395286" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL4R: 1.05-fold Down; FDR = 0.803; PValue = 0.499; mean CPM = 193.5; interleukin 4 receptor" ID="ID_1376830800" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CBL: 1.05-fold Down; FDR = 0.824; PValue = 0.524; mean CPM = 51.06; Cas-Br-M (murine) ecotropic retroviral transforming sequence" ID="ID_1248787135" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1374209277" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB1: 1.04-fold Up; FDR = 0.88; PValue = 0.6; mean CPM = 30.80; Uncharacterized protein" ID="ID_244295976" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL4: 1.27-fold Down; FDR = 0.933; PValue = 0.745; mean CPM = 0.8077; interleukin 4" ID="ID_1049356357" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="MIP1a / CCL3: FDR = 5.64e-14, PValue = 1.77e-14" ID="ID_1751363900" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CCL2: 24.6-fold Up; FDR = 1.83e-15; PValue = 1.69e-17; mean CPM = 668.2; Macaca mulatta chemokine (C-C motif) ligand 2 (CCL2), mRNA." ID="ID_22661951" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2B: 3.54-fold Up; FDR = 1.24e-07; PValue = 7.07e-09; mean CPM = 5.971; PTK2B protein tyrosine kinase 2 beta" ID="ID_1737663466" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1525268303" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALM3: 1.41-fold Down; FDR = 0.000714; PValue = 0.000115; mean CPM = 94.24; calmodulin 3 (phosphorylase kinase, delta)" ID="ID_600765047" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCR4: 4.65-fold Down; FDR = 0.00226; PValue = 0.000426; mean CPM = 2.073; chemokine (C-X-C motif) receptor 4" ID="ID_1891235222" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG1: 1.31-fold Down; FDR = 0.00352; PValue = 0.000707; mean CPM = 53.66; phospholipase C, gamma 1" ID="ID_811340265" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_959960509" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALM1: 1.18-fold Down; FDR = 0.104; PValue = 0.0368; mean CPM = 292.9; calmodulin 1 (phosphorylase kinase, delta)" ID="ID_1643716789" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1714135164" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALM1: 1.11-fold Up; FDR = 0.343; PValue = 0.16; mean CPM = 412.7; Calmodulin; Uncharacterized protein" ID="ID_330031996" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_456326925" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR5: 1.56-fold Down; FDR = 0.487; PValue = 0.249; mean CPM = 1.064; chemokine (C-C motif) receptor 5" ID="ID_1074450427" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL12: 1.27-fold Down; FDR = 0.488; PValue = 0.251; mean CPM = 4.383; chemokine (C-X-C motif) ligand 12" ID="ID_101467390" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCB: 1.86-fold Up; FDR = 0.727; PValue = 0.43; mean CPM = 0.8705; protein kinase C, beta" ID="ID_387946097" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAQ: 1.05-fold Down; FDR = 0.889; PValue = 0.611; mean CPM = 9.623; Guanine nucleotide-binding protein G(Q) subunit alpha; Uncharacterized protein" ID="ID_1660709224" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016883: 1.11-fold Down; FDR = 0.97; PValue = 0.811; mean CPM = 0.8838; Uncharacterized protein" ID="ID_1210113413" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAQ: No Change; FDR = 1; PValue = 0.975; mean CPM = 15.20; guanine nucleotide binding protein (G protein), q polypeptide" ID="ID_733482255" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="p38: FDR = 2.28e-13, PValue = 7.6e-14" ID="ID_279242324" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1460623453" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_292367280" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MEF2D: 1.73-fold Down; FDR = 2.02e-08; PValue = 9.5e-10; mean CPM = 61.43; myocyte enhancer factor 2D" ID="ID_887389625" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DDIT3: 2.05-fold Up; FDR = 1.46e-06; PValue = 1.09e-07; mean CPM = 45.52; DNA-damage-inducible transcript 3" ID="ID_1597067601" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA5: 3.28-fold Up; FDR = 1.4e-05; PValue = 1.36e-06; mean CPM = 2.288; ribosomal protein S6 kinase, 90kDa, polypeptide 5" ID="ID_472753430" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF2: 1.34-fold Up; FDR = 0.000403; PValue = 6.01e-05; mean CPM = 39.83; activating transcription factor 2" ID="ID_1963156743" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_448738976" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAX: 1.28-fold Up; FDR = 0.00569; PValue = 0.00123; mean CPM = 29.78; MYC associated factor X" ID="ID_1158639456" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB1: 1.21-fold Up; FDR = 0.0313; PValue = 0.00884; mean CPM = 36.07; cAMP responsive element binding protein 1" ID="ID_1960736999" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRADD: 1.22-fold Up; FDR = 0.0319; PValue = 0.00907; mean CPM = 34.75; TNFRSF1A-associated via death domain" ID="ID_447376403" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFBR1: 1.2-fold Up; FDR = 0.037; PValue = 0.0108; mean CPM = 90.92; transforming growth factor, beta receptor 1" ID="ID_1689488894" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_1570866552" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_1066635439" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MKNK1: 1.27-fold Down; FDR = 0.0706; PValue = 0.0232; mean CPM = 9.169; MAP kinase interacting serine/threonine kinase 1" ID="ID_161507479" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K9: 1.62-fold Down; FDR = 0.177; PValue = 0.0705; mean CPM = 1.806; mitogen-activated protein kinase kinase kinase 9" ID="ID_1503385814" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1084629189" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_1482789555" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPKAPK5: 1.15-fold Down; FDR = 0.297; PValue = 0.134; mean CPM = 13.06; mitogen-activated protein kinase-activated protein kinase 5" ID="ID_1958437351" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1722335614" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K5: 1.21-fold Down; FDR = 0.6; PValue = 0.33; mean CPM = 8.023; mitogen-activated protein kinase kinase kinase 5" ID="ID_1631555554" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDC42: 1.07-fold Down; FDR = 0.608; PValue = 0.335; mean CPM = 91.67; cell division cycle 42" ID="ID_744896229" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPKAPK2: 1.06-fold Down; FDR = 0.733; PValue = 0.435; mean CPM = 82.16; mitogen-activated protein kinase-activated protein kinase 2" ID="ID_168991264" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLA2G4A: 1.08-fold Down; FDR = 0.836; PValue = 0.541; mean CPM = 40.53; phospholipase A2, group IVA (cytosolic, calcium-dependent)" ID="ID_1748236720" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASGRF1: 1.14-fold Down; FDR = 0.903; PValue = 0.648; mean CPM = 1.594; Ras protein-specific guanine nucleotide-releasing factor 1" ID="ID_543340205" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB2: 1.05-fold Down; FDR = 0.903; PValue = 0.655; mean CPM = 110.8; transforming growth factor, beta 2" ID="ID_106990957" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_999500222" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_1425945210" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_349523426" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DAXX: No Change; FDR = 1; PValue = 0.984; mean CPM = 106.5; Death domain-associated protein 6 (Daxx)(hDaxx)(Fas death domain-associated protein)(ETS1-associated protein 1)(EAP1)" ID="ID_1205138632" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="MCP-1 / CCL2: FDR = 2.65e-13, PValue = 9.31e-14" ID="ID_421797735" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CCL2: 24.6-fold Up; FDR = 1.83e-15; PValue = 1.69e-17; mean CPM = 668.2; Macaca mulatta chemokine (C-C motif) ligand 2 (CCL2), mRNA." ID="ID_582604061" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_524276512" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_1291728805" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1988447061" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR2: 1.51-fold Up; FDR = 0.823; PValue = 0.523; mean CPM = 0.8333; chemokine (C-C motif) receptor 2" ID="ID_941939785" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR4: 1.74-fold Up; FDR = 0.831; PValue = 0.533; mean CPM = 0.8536; chemokine (C-C motif) receptor 4" ID="ID_762051258" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLA2G4A: 1.08-fold Down; FDR = 0.836; PValue = 0.541; mean CPM = 40.53; phospholipase A2, group IVA (cytosolic, calcium-dependent)" ID="ID_110938007" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLA2G6: 1.03-fold Up; FDR = 0.958; PValue = 0.79; mean CPM = 10.46; phospholipase A2, group VI (cytosolic, calcium-independent)" ID="ID_1185556580" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Cell adhesion molecules: FDR = 1.11e-12, PValue = 4.1e-13" ID="ID_494746016" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="ENSMMUP00000027180: 6.97-fold Up; FDR = 1.24e-21; PValue = 3.39e-24; mean CPM = 285.4; Uncharacterized protein" ID="ID_202752492" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000027180: 6.97-fold Up; FDR = 1.24e-21; PValue = 3.39e-24; mean CPM = 285.4; Uncharacterized protein" ID="ID_1392025817" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000005183: 4.07-fold Up; FDR = 2.87e-21; PValue = 8.51e-24; mean CPM = 164.7; Uncharacterized protein" ID="ID_1989012746" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000005183: 4.07-fold Up; FDR = 2.87e-21; PValue = 8.51e-24; mean CPM = 164.7; Uncharacterized protein" ID="ID_1873106525" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD274: 21.5-fold Up; FDR = 4.64e-21; PValue = 1.39e-23; mean CPM = 62.62; Macaca mulatta CD274 molecule (CD274), mRNA." ID="ID_354801313" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-B: 6.07-fold Up; FDR = 2.71e-19; PValue = 1.2e-21; mean CPM = 2098; Uncharacterized protein" ID="ID_851639377" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICAM1: 24.6-fold Up; FDR = 2.39e-17; PValue = 1.64e-19; mean CPM = 232.4; intercellular adhesion molecule 1" ID="ID_86503492" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DMB: 17.5-fold Up; FDR = 2.77e-15; PValue = 2.66e-17; mean CPM = 9.464; HLA class II histocompatibility antigen, DM beta chain Precursor (MHC class II antigen DMB)(Really interesting new gene 7 protein)" ID="ID_1130650630" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DPA1: 107-fold Up; FDR = 5.97e-15; PValue = 6.11e-17; mean CPM = 17.08; HLA class II histocompatibility antigen, DP alpha 1 chain Precursor (HLA-SB alpha chain)(MHC class II DP3-alpha)(DP(W3))(DP(W4))" ID="ID_291472756" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDCD1LG2: 5.48-fold Up; FDR = 1.11e-13; PValue = 1.46e-15; mean CPM = 28.34; programmed cell death 1 ligand 2" ID="ID_1857996530" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DQB1: 31.1-fold Up; FDR = 6.93e-13; PValue = 1.1e-14; mean CPM = 6.675; Macaca mulatta MHC class II antigen (MAMU-DRB), mRNA." ID="ID_904440911" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD276: 1.83-fold Down; FDR = 2.04e-11; PValue = 4.56e-13; mean CPM = 65.28; CD276 molecule" ID="ID_1868694603" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAV: 2.64-fold Down; FDR = 6.04e-11; PValue = 1.51e-12; mean CPM = 337.3; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)" ID="ID_1974662322" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDH2: 2.24-fold Down; FDR = 2.51e-10; PValue = 7.39e-12; mean CPM = 402.4; cadherin 2, type 1, N-cadherin (neuronal)" ID="ID_1746863125" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPRF: 2.51-fold Down; FDR = 5.51e-10; PValue = 1.77e-11; mean CPM = 184.0; protein tyrosine phosphatase, receptor type, F" ID="ID_1378463149" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB8: 3.97-fold Up; FDR = 6.37e-10; PValue = 2.06e-11; mean CPM = 11.37; integrin, beta 8" ID="ID_122193181" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VCAN: 2.98-fold Down; FDR = 6.04e-09; PValue = 2.48e-10; mean CPM = 2567; versican" ID="ID_1488248523" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SDC2: 1.91-fold Down; FDR = 6.94e-09; PValue = 2.87e-10; mean CPM = 168.5; syndecan 2" ID="ID_1694865017" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CNTNAP1: 2.24-fold Down; FDR = 1.39e-08; PValue = 6.26e-10; mean CPM = 15.44; contactin associated protein 1" ID="ID_1721332435" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAM3: 1.66-fold Down; FDR = 1.46e-08; PValue = 6.62e-10; mean CPM = 47.05; junctional adhesion molecule 3" ID="ID_1843384239" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA1: 15.1-fold Up; FDR = 1.9e-08; PValue = 8.86e-10; mean CPM = 3.665; HLA class II histocompatibility antigen, DQ alpha 1 chain precursor" ID="ID_148283030" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DPB1: 7.73-fold Up; FDR = 4.73e-08; PValue = 2.45e-09; mean CPM = 1.528; Macaca mulatta major histocompatibility complex, class II, DP beta (MAMU-DPB), mRNA." ID="ID_316178620" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA8: 4.04-fold Down; FDR = 5.89e-08; PValue = 3.12e-09; mean CPM = 145.8; integrin, alpha 8" ID="ID_664361548" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SDC4: 1.79-fold Up; FDR = 1.95e-07; PValue = 1.16e-08; mean CPM = 109.0; syndecan 4" ID="ID_70442355" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SDC1: 2.19-fold Down; FDR = 2.55e-05; PValue = 2.66e-06; mean CPM = 12.60; syndecan 1" ID="ID_1050374501" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD99: 1.41-fold Down; FDR = 4.92e-05; PValue = 5.57e-06; mean CPM = 352.5; CD99 molecule" ID="ID_596947101" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLGN2: 1.64-fold Down; FDR = 6.24e-05; PValue = 7.29e-06; mean CPM = 14.59; neuroligin 2" ID="ID_783084666" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPRC: 6.08-fold Up; FDR = 0.000285; PValue = 4.07e-05; mean CPM = 1.220; protein tyrosine phosphatase, receptor type, C" ID="ID_1924700004" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40: 2.76-fold Up; FDR = 0.00039; PValue = 5.79e-05; mean CPM = 9.139; CD40 molecule, TNF receptor superfamily member 5" ID="ID_1538739884" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NRCAM: 2.04-fold Down; FDR = 0.00042; PValue = 6.29e-05; mean CPM = 7.571; Uncharacterized protein" ID="ID_1109103116" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD34: 2.84-fold Up; FDR = 0.000647; PValue = 0.000102; mean CPM = 1.700; CD34 molecule" ID="ID_1434303786" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLDN2: 2.23-fold Down; FDR = 0.00218; PValue = 0.000409; mean CPM = 1.832; claudin 2" ID="ID_1276629754" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GLG1: 1.28-fold Down; FDR = 0.00336; PValue = 0.000671; mean CPM = 229.6; golgi glycoprotein 1" ID="ID_406100133" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CADM3: 2.54-fold Up; FDR = 0.00366; PValue = 0.000742; mean CPM = 3.739; cell adhesion molecule 3" ID="ID_1312880234" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NRXN2: 3.89-fold Down; FDR = 0.0116; PValue = 0.0028; mean CPM = 1.629; neurexin 2" ID="ID_1148835104" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SELE: 4.04-fold Down; FDR = 0.0118; PValue = 0.00285; mean CPM = 0.9962; selectin E" ID="ID_460460152" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="OCLN: 2.09-fold Down; FDR = 0.012; PValue = 0.00291; mean CPM = 2.598; occludin" ID="ID_394748496" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CNTN1: 2.61-fold Down; FDR = 0.0121; PValue = 0.00294; mean CPM = 1.505; contactin 1" ID="ID_242027159" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPRM: 1.23-fold Down; FDR = 0.0136; PValue = 0.00334; mean CPM = 137.6; protein tyrosine phosphatase, receptor type, M" ID="ID_1197449325" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB2: 1.55-fold Down; FDR = 0.0187; PValue = 0.00485; mean CPM = 34.87; Integrin beta" ID="ID_1765194739" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NEGR1: 1.42-fold Down; FDR = 0.0227; PValue = 0.00608; mean CPM = 10.40; neuronal growth regulator 1" ID="ID_1138219621" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLDN19: 3.2-fold Down; FDR = 0.0255; PValue = 0.00696; mean CPM = 0.9715; claudin 19" ID="ID_1037937832" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDH15: 2.95-fold Down; FDR = 0.0333; PValue = 0.00955; mean CPM = 0.9244; cadherin 15, type 1, M-cadherin (myotubule)" ID="ID_915137531" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VCAM1: 1.53-fold Up; FDR = 0.0353; PValue = 0.0102; mean CPM = 110.0; vascular cell adhesion molecule 1" ID="ID_177284104" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PVRL3: 1.22-fold Up; FDR = 0.037; PValue = 0.0108; mean CPM = 29.58; poliovirus receptor-related 3" ID="ID_1017683942" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SDC3: 1.2-fold Down; FDR = 0.0585; PValue = 0.0186; mean CPM = 64.27; syndecan 3" ID="ID_3843566" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CNTN2: 2.73-fold Down; FDR = 0.0614; PValue = 0.0196; mean CPM = 0.9153; contactin 2 (axonal)" ID="ID_1511550937" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DOA: 2.74-fold Up; FDR = 0.0694; PValue = 0.0227; mean CPM = 0.9089; HLA class II histocompatibility antigen, DO alpha chain Precursor (MHC class II antigen DOA)(MHC DZ alpha)(MHC DN-alpha)" ID="ID_1462458011" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB1: 1.23-fold Up; FDR = 0.0759; PValue = 0.0253; mean CPM = 2700; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)" ID="ID_1585898169" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLGN1: 1.91-fold Down; FDR = 0.0998; PValue = 0.0349; mean CPM = 1.272; neuroligin 1" ID="ID_1369436550" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLDN1: 1.57-fold Up; FDR = 0.1; PValue = 0.0352; mean CPM = 7.527; claudin 1" ID="ID_408179142" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="F11R: 1.41-fold Down; FDR = 0.113; PValue = 0.0407; mean CPM = 11.52; Uncharacterized protein" ID="ID_1778311406" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PVRL1: 1.47-fold Down; FDR = 0.119; PValue = 0.0431; mean CPM = 2.907; poliovirus receptor-related 1 (herpesvirus entry mediator C)" ID="ID_343391447" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPN: 2.27-fold Down; FDR = 0.157; PValue = 0.0608; mean CPM = 0.9319; sialophorin" ID="ID_1674200549" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLDN22: 1.51-fold Down; FDR = 0.17; PValue = 0.0669; mean CPM = 1.862; claudin 22" ID="ID_92178728" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLDN4: 2-fold Down; FDR = 0.175; PValue = 0.0694; mean CPM = 1.622; claudin 4" ID="ID_1269854262" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ALCAM: 1.26-fold Down; FDR = 0.234; PValue = 0.0995; mean CPM = 41.17; activated leukocyte cell adhesion molecule" ID="ID_450638762" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLDN11: 1.67-fold Down; FDR = 0.304; PValue = 0.138; mean CPM = 1.115; claudin 11" ID="ID_1822341197" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDH3: 1.78-fold Down; FDR = 0.349; PValue = 0.163; mean CPM = 0.9566; Uncharacterized protein" ID="ID_1031714633" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014796: 1.77-fold Up; FDR = 0.381; PValue = 0.182; mean CPM = 0.9085; Uncharacterized protein" ID="ID_397285137" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLDN5: 2.59-fold Down; FDR = 0.425; PValue = 0.209; mean CPM = 0.8375; claudin 5" ID="ID_1623280613" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CNTNAP2: 1.48-fold Down; FDR = 0.515; PValue = 0.268; mean CPM = 1.160; contactin associated protein-like 2" ID="ID_1803149500" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PVRL2: 1.08-fold Down; FDR = 0.552; PValue = 0.295; mean CPM = 35.47; poliovirus receptor-related 2 (herpesvirus entry mediator B)" ID="ID_578322310" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLDN14: 1.57-fold Down; FDR = 0.588; PValue = 0.321; mean CPM = 0.8761; claudin 14" ID="ID_5927139" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA9: 1.3-fold Down; FDR = 0.595; PValue = 0.326; mean CPM = 1.685; integrin, alpha 9" ID="ID_476967723" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="L1CAM: 1.34-fold Down; FDR = 0.601; PValue = 0.331; mean CPM = 2.064; Uncharacterized protein" ID="ID_225329423" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLDN16: 1.44-fold Down; FDR = 0.623; PValue = 0.346; mean CPM = 1.045; claudin 16" ID="ID_1398966682" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICAM3: 1.1-fold Down; FDR = 0.685; PValue = 0.395; mean CPM = 7.797; intercellular adhesion molecule 3" ID="ID_268980644" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDH4: 1.42-fold Down; FDR = 0.714; PValue = 0.418; mean CPM = 0.8874; Uncharacterized protein" ID="ID_623866364" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA4: 1.16-fold Down; FDR = 0.722; PValue = 0.425; mean CPM = 5.425; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)" ID="ID_1953725811" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAM: 1.44-fold Down; FDR = 0.73; PValue = 0.432; mean CPM = 0.9052; integrin, alpha M (complement component 3 receptor 3 subunit)" ID="ID_1418931242" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLDN15: 1.11-fold Down; FDR = 0.738; PValue = 0.439; mean CPM = 5.245; claudin 15" ID="ID_1086739300" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLDN6: 1.37-fold Down; FDR = 0.751; PValue = 0.452; mean CPM = 0.9260; claudin 6" ID="ID_278746512" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLGN3: 1.27-fold Down; FDR = 0.783; PValue = 0.48; mean CPM = 1.180; neuroligin 3" ID="ID_1842011587" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD4: 1.27-fold Up; FDR = 0.807; PValue = 0.503; mean CPM = 1.122; CD4 molecule" ID="ID_485828534" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTLA4: 1.41-fold Down; FDR = 0.827; PValue = 0.527; mean CPM = 0.8017; cytotoxic T-lymphocyte-associated protein 4" ID="ID_1231967194" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLDN18: 1.49-fold Down; FDR = 0.833; PValue = 0.535; mean CPM = 0.8235; claudin 18" ID="ID_882039541" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICAM2: 1.26-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 0.9289; intercellular adhesion molecule 2" ID="ID_1913069670" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD58: 1.04-fold Down; FDR = 0.889; PValue = 0.612; mean CPM = 21.84; CD58 molecule" ID="ID_1219616622" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DRB: 1.28-fold Up; FDR = 0.898; PValue = 0.624; mean CPM = 0.8112; MHC class II antigen; Uncharacterized protein" ID="ID_54793482" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SIGLEC1: 1.23-fold Down; FDR = 0.899; PValue = 0.626; mean CPM = 0.9801; sialic acid binding Ig-like lectin 1, sialoadhesin" ID="ID_354569148" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MPZL1: 1.03-fold Up; FDR = 0.902; PValue = 0.639; mean CPM = 84.36; myelin protein zero-like 1" ID="ID_1026611577" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD2: 1.42-fold Up; FDR = 0.903; PValue = 0.641; mean CPM = 0.8179; CD2 molecule" ID="ID_166716087" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDCD1: 1.5-fold Down; FDR = 0.903; PValue = 0.644; mean CPM = 0.8258; programmed cell death 1" ID="ID_1807043783" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000024680: 1.21-fold Down; FDR = 0.903; PValue = 0.647; mean CPM = 0.7890; Uncharacterized protein" ID="ID_1102786793" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLDN8: 1.13-fold Up; FDR = 0.908; PValue = 0.677; mean CPM = 0.7894; claudin 8" ID="ID_484937696" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA2: 1.13-fold Up; FDR = 0.908; PValue = 0.681; mean CPM = 0.7877; HLA class II histocompatibility antigen, DQ alpha 2 chain Precursor (HLA class II histocompatibility antigen, DQ(6) alpha chain)(DX alpha chain)(HLA-DQA1)" ID="ID_507201135" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICOSLG: 1.07-fold Down; FDR = 0.909; PValue = 0.684; mean CPM = 6.739; inducible T-cell co-stimulator ligand" ID="ID_1724969417" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MADCAM1: 1.11-fold Up; FDR = 0.909; PValue = 0.688; mean CPM = 0.7934; mucosal vascular addressin cell adhesion molecule 1" ID="ID_1899201284" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICOS: 1.19-fold Up; FDR = 0.931; PValue = 0.741; mean CPM = 0.8158; Uncharacterized protein" ID="ID_236151022" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD6: 1.11-fold Up; FDR = 0.931; PValue = 0.742; mean CPM = 1.320; CD6 molecule" ID="ID_1491800141" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SELP: 1.2-fold Down; FDR = 0.942; PValue = 0.76; mean CPM = 0.8693; selectin P (granule membrane protein 140kDa, antigen CD62)" ID="ID_1162346598" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDH5: 1.13-fold Down; FDR = 0.95; PValue = 0.776; mean CPM = 0.8935; cadherin 5, type 2 (vascular endothelium)" ID="ID_1750239565" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAG: 1.17-fold Up; FDR = 0.953; PValue = 0.782; mean CPM = 0.8629; myelin associated glycoprotein" ID="ID_1218770093" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLDN10: 1.22-fold Down; FDR = 0.957; PValue = 0.79; mean CPM = 0.8494; claudin 10" ID="ID_963875057" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD80: 1.08-fold Up; FDR = 0.971; PValue = 0.812; mean CPM = 1.157; CD80 molecule" ID="ID_1819621900" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NEO1: 1.03-fold Down; FDR = 0.974; PValue = 0.816; mean CPM = 107.7; neogenin homolog 1 (chicken)" ID="ID_632564938" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDH1: 1.06-fold Down; FDR = 1; PValue = 0.899; mean CPM = 0.8823; cadherin 1, type 1, E-cadherin (epithelial)" ID="ID_1675416779" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD22: 1.18-fold Down; FDR = 1; PValue = 0.928; mean CPM = 0.8572; CD22 molecule" ID="ID_209697196" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAL: 1.03-fold Up; FDR = 1; PValue = 0.95; mean CPM = 1.035; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)" ID="ID_206507526" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB7: 1.01-fold Down; FDR = 1; PValue = 0.968; mean CPM = 2.025; integrin, beta 7" ID="ID_548050976" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLDN9: 1.07-fold Down; FDR = 1; PValue = 0.969; mean CPM = 0.8006; claudin 9" ID="ID_1909218128" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD8A: No Change; FDR = 1; PValue = 0.98; mean CPM = 0.8052; CD8a molecule" ID="ID_488134250" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40LG: 1.01-fold Down; FDR = 1; PValue = 0.982; mean CPM = 0.8653; CD40 ligand" ID="ID_1489459468" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD86: 1.01-fold Down; FDR = 1; PValue = 0.99; mean CPM = 0.8012; CD86 molecule" ID="ID_766334175" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SELL: 1.04-fold Up; FDR = 1; PValue = 0.995; mean CPM = 0.8177; Macaca mulatta selectin L (SELL), mRNA." ID="ID_1251186024" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NRXN1: 1.07-fold Up; FDR = 1; PValue = 0.999; mean CPM = 0.8440; neurexin 1" ID="ID_1265397702" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ESAM: 1.01-fold Down; FDR = 1; PValue = 1; mean CPM = 1.217; endothelial cell adhesion molecule" ID="ID_1721915821" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD226: No Change; FDR = 1; PValue = 1; mean CPM = 0.7800; CD226 molecule" ID="ID_650816344" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLDN17: No Change; FDR = 1; PValue = 1; mean CPM = 0.7843; claudin 17" ID="ID_912035372" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-5 : FDR = 2.2e-12, PValue = 8.54e-13" ID="ID_481205241" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_405164555" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1018458746" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5A: 2.28-fold Up; FDR = 6.87e-14; PValue = 8.58e-16; mean CPM = 21.55; signal transducer and activator of transcription 5A" ID="ID_906253148" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_660609995" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_1615050368" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_724808506" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_297521787" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_858769702" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL11: 6.86-fold Up; FDR = 2.69e-05; PValue = 2.82e-06; mean CPM = 4.204; chemokine (C-C motif) ligand 11" ID="ID_1703739469" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB2: 1.38-fold Down; FDR = 4.66e-05; PValue = 5.24e-06; mean CPM = 61.90; ribosomal protein S6 kinase, 70kDa, polypeptide 2" ID="ID_1509754141" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTOR: 1.3-fold Down; FDR = 0.00117; PValue = 0.000201; mean CPM = 107.5; mechanistic target of rapamycin (serine/threonine kinase)" ID="ID_1473032200" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_333160509" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA1: 1.25-fold Down; FDR = 0.0241; PValue = 0.00652; mean CPM = 21.28; ribosomal protein S6 kinase, 90kDa, polypeptide 1" ID="ID_741968679" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_905708745" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_953953372" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIM1: 1.39-fold Down; FDR = 0.0325; PValue = 0.00926; mean CPM = 21.11; pim-1 oncogene" ID="ID_192266377" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_1265040336" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_1949526222" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_773662196" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3A: 1.18-fold Down; FDR = 0.097; PValue = 0.0338; mean CPM = 25.14; Glycogen synthase kinase-3 alpha; Uncharacterized protein" ID="ID_1861731471" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_1712379422" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPRED1: 1.15-fold Up; FDR = 0.143; PValue = 0.0543; mean CPM = 41.74; sprouty-related, EVH1 domain containing 1" ID="ID_1416907270" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_148346821" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1489212154" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_330792502" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_909768988" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2: 1.48-fold Up; FDR = 0.384; PValue = 0.184; mean CPM = 1.344; Uncharacterized protein" ID="ID_1303718007" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_691049801" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_1576304091" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOXO3: 1.08-fold Down; FDR = 0.55; PValue = 0.294; mean CPM = 48.45; forkhead box O3" ID="ID_613832555" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6: 1.08-fold Up; FDR = 0.584; PValue = 0.318; mean CPM = 892.5; ribosomal protein S6" ID="ID_694281934" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_195531259" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD4: 1.27-fold Up; FDR = 0.807; PValue = 0.503; mean CPM = 1.122; CD4 molecule" ID="ID_1847614076" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1689496373" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB1: 1.04-fold Up; FDR = 0.88; PValue = 0.6; mean CPM = 30.80; Uncharacterized protein" ID="ID_1786774938" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DRB: 1.28-fold Up; FDR = 0.898; PValue = 0.624; mean CPM = 0.8112; MHC class II antigen; Uncharacterized protein" ID="ID_1426309506" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR3: 1.43-fold Up; FDR = 0.906; PValue = 0.665; mean CPM = 0.8397; chemokine (C-C motif) receptor 3" ID="ID_1064084348" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL4: 1.27-fold Down; FDR = 0.933; PValue = 0.745; mean CPM = 0.8077; interleukin 4" ID="ID_1935440111" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_1784574220" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL5RA: 1.1-fold Up; FDR = 0.958; PValue = 0.791; mean CPM = 0.8108; interleukin 5 receptor, alpha" ID="ID_613243348" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL5: 1.05-fold Down; FDR = 1; PValue = 0.862; mean CPM = 1.367; interleukin 5 (colony-stimulating factor, eosinophil)" ID="ID_1595108890" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BTK: No Change; FDR = 1; PValue = 0.965; mean CPM = 0.8336; Bruton agammaglobulinemia tyrosine kinase" ID="ID_309100645" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SYK: 1.11-fold Up; FDR = 1; PValue = 0.977; mean CPM = 0.8420; spleen tyrosine kinase" ID="ID_1966932601" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="RANTES / CCL5: FDR = 3.68e-12, PValue = 1.5e-12" ID="ID_234613622" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CCL2: 24.6-fold Up; FDR = 1.83e-15; PValue = 1.69e-17; mean CPM = 668.2; Macaca mulatta chemokine (C-C motif) ligand 2 (CCL2), mRNA." ID="ID_1527647742" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNB4: 2.14-fold Up; FDR = 2.52e-09; PValue = 9.35e-11; mean CPM = 33.45; guanine nucleotide binding protein (G protein), beta polypeptide 4" ID="ID_300463261" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2B: 3.54-fold Up; FDR = 1.24e-07; PValue = 7.07e-09; mean CPM = 5.971; PTK2B protein tyrosine kinase 2 beta" ID="ID_624435020" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL5: 6.74-fold Up; FDR = 2.65e-07; PValue = 1.64e-08; mean CPM = 30.35; chemokine (C-C motif) ligand 5" ID="ID_584210340" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNA1C: 2.79-fold Down; FDR = 3.33e-07; PValue = 2.1e-08; mean CPM = 34.91; Uncharacterized protein" ID="ID_1188562379" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1263220989" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCE: 1.73-fold Up; FDR = 0.00013; PValue = 1.67e-05; mean CPM = 10.87; protein kinase C, epsilon" ID="ID_1786244335" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNB3: 1.91-fold Down; FDR = 0.000162; PValue = 2.14e-05; mean CPM = 7.202; guanine nucleotide binding protein (G protein), beta polypeptide 3" ID="ID_1979216642" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALM3: 1.41-fold Down; FDR = 0.000714; PValue = 0.000115; mean CPM = 94.24; calmodulin 3 (phosphorylase kinase, delta)" ID="ID_1545558974" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNA12: 1.32-fold Down; FDR = 0.000955; PValue = 0.00016; mean CPM = 33.75; Uncharacterized protein" ID="ID_1343507699" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCH: 1.98-fold Down; FDR = 0.00105; PValue = 0.000179; mean CPM = 3.182; protein kinase C, eta" ID="ID_1497237509" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAS1: 1.31-fold Down; FDR = 0.00158; PValue = 0.000283; mean CPM = 564.9; Uncharacterized protein" ID="ID_1676559619" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKD3: 1.29-fold Up; FDR = 0.00214; PValue = 0.0004; mean CPM = 43.43; protein kinase D3" ID="ID_615748734" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCR4: 4.65-fold Down; FDR = 0.00226; PValue = 0.000426; mean CPM = 2.073; chemokine (C-X-C motif) receptor 4" ID="ID_693298230" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG1: 1.31-fold Down; FDR = 0.00352; PValue = 0.000707; mean CPM = 53.66; phospholipase C, gamma 1" ID="ID_1861828934" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNA2D4: 1.71-fold Up; FDR = 0.00375; PValue = 0.000764; mean CPM = 4.238; calcium channel, voltage-dependent, alpha 2/delta subunit 4" ID="ID_1287365144" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_198448620" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCZ: 1.51-fold Up; FDR = 0.0152; PValue = 0.00381; mean CPM = 10.46; protein kinase C, zeta" ID="ID_212720566" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_245435146" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNA1F: 2.4-fold Down; FDR = 0.0315; PValue = 0.00892; mean CPM = 1.129; calcium channel, voltage-dependent, L type, alpha 1F subunit" ID="ID_1311922115" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNA13: 1.25-fold Up; FDR = 0.0428; PValue = 0.0128; mean CPM = 15.41; guanine nucleotide binding protein (G protein), alpha 13" ID="ID_745006777" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNA1D: 2.26-fold Down; FDR = 0.0434; PValue = 0.013; mean CPM = 1.171; calcium channel, voltage-dependent, L type, alpha 1D subunit" ID="ID_1228520327" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL3: 2.04-fold Down; FDR = 0.067; PValue = 0.0218; mean CPM = 3.575; chemokine (C-C motif) ligand 3" ID="ID_1065468205" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNA2D3: 1.74-fold Down; FDR = 0.0883; PValue = 0.0302; mean CPM = 6.008; calcium channel, voltage-dependent, alpha 2/delta subunit 3" ID="ID_1676124559" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALM1: 1.18-fold Down; FDR = 0.104; PValue = 0.0368; mean CPM = 292.9; calmodulin 1 (phosphorylase kinase, delta)" ID="ID_1612128863" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG2: 1.64-fold Up; FDR = 0.117; PValue = 0.0421; mean CPM = 2.320; guanine nucleotide binding protein (G protein), gamma 2" ID="ID_1887415267" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_1147722709" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_12981816" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG3: 1.6-fold Down; FDR = 0.155; PValue = 0.0601; mean CPM = 1.706; guanine nucleotide binding protein (G protein), gamma 3" ID="ID_292529073" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNB1: 1.31-fold Down; FDR = 0.157; PValue = 0.0608; mean CPM = 5.053; calcium channel, voltage-dependent, beta 1 subunit" ID="ID_773394625" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALM1: 1.11-fold Up; FDR = 0.343; PValue = 0.16; mean CPM = 412.7; Calmodulin; Uncharacterized protein" ID="ID_1570881515" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNA14: 1.45-fold Up; FDR = 0.381; PValue = 0.182; mean CPM = 1.368; guanine nucleotide binding protein (G protein), alpha 14" ID="ID_513804800" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_650662935" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKD1: 1.14-fold Down; FDR = 0.433; PValue = 0.215; mean CPM = 41.81; protein kinase D1" ID="ID_29805690" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNB3: 1.1-fold Down; FDR = 0.459; PValue = 0.231; mean CPM = 26.21; calcium channel, voltage-dependent, beta 3 subunit" ID="ID_1338732329" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNA11: 1.09-fold Down; FDR = 0.485; PValue = 0.248; mean CPM = 43.16; guanine nucleotide binding protein (G protein), alpha 11 (Gq class)" ID="ID_1291918548" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR5: 1.56-fold Down; FDR = 0.487; PValue = 0.249; mean CPM = 1.064; chemokine (C-C motif) receptor 5" ID="ID_1468070694" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL12: 1.27-fold Down; FDR = 0.488; PValue = 0.251; mean CPM = 4.383; chemokine (C-X-C motif) ligand 12" ID="ID_1368052761" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCI: 1.08-fold Up; FDR = 0.518; PValue = 0.271; mean CPM = 47.99; protein kinase C, iota" ID="ID_24320453" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCQ: 1.56-fold Up; FDR = 0.522; PValue = 0.274; mean CPM = 1.047; Uncharacterized protein" ID="ID_673971786" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG4: 1.65-fold Down; FDR = 0.524; PValue = 0.275; mean CPM = 0.8771; guanine nucleotide binding protein (G protein), gamma 4" ID="ID_448854447" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAL: 1.29-fold Down; FDR = 0.53; PValue = 0.279; mean CPM = 1.742; guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type" ID="ID_1942611975" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNA2D1: 1.13-fold Down; FDR = 0.562; PValue = 0.303; mean CPM = 10.13; calcium channel, voltage-dependent, alpha 2/delta subunit 1" ID="ID_77485381" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNB1: 1.08-fold Down; FDR = 0.565; PValue = 0.305; mean CPM = 299.4; guanine nucleotide binding protein (G protein), beta polypeptide 1" ID="ID_290445384" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNA1I: 1.48-fold Down; FDR = 0.57; PValue = 0.309; mean CPM = 0.9895; Uncharacterized protein" ID="ID_1442623987" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNB2: 1.4-fold Down; FDR = 0.573; PValue = 0.31; mean CPM = 1.119; calcium channel, voltage-dependent, beta 2 subunit" ID="ID_878479058" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCG: 1.47-fold Down; FDR = 0.609; PValue = 0.336; mean CPM = 0.9297; protein kinase C, gamma" ID="ID_999071533" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNB2: 1.06-fold Down; FDR = 0.685; PValue = 0.395; mean CPM = 129.1; guanine nucleotide binding protein (G protein), beta polypeptide 2" ID="ID_69326031" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCD: 1.06-fold Up; FDR = 0.696; PValue = 0.404; mean CPM = 37.45; protein kinase C, delta" ID="ID_1974062755" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCB: 1.86-fold Up; FDR = 0.727; PValue = 0.43; mean CPM = 0.8705; protein kinase C, beta" ID="ID_1808076508" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNA1H: 1.38-fold Down; FDR = 0.735; PValue = 0.437; mean CPM = 0.9035; calcium channel, voltage-dependent, T type, alpha 1H subunit" ID="ID_17061289" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNG1: 1.82-fold Up; FDR = 0.74; PValue = 0.442; mean CPM = 0.8669; calcium channel, voltage-dependent, gamma subunit 1" ID="ID_155448287" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD4: 1.27-fold Up; FDR = 0.807; PValue = 0.503; mean CPM = 1.122; CD4 molecule" ID="ID_562116561" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNA1S: 1.33-fold Down; FDR = 0.823; PValue = 0.522; mean CPM = 0.8938; calcium channel, voltage-dependent, L type, alpha 1S subunit" ID="ID_394160776" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNG7: 1.29-fold Down; FDR = 0.836; PValue = 0.541; mean CPM = 0.8254; calcium channel, voltage-dependent, gamma subunit 7" ID="ID_1309562952" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAQ: 1.05-fold Down; FDR = 0.889; PValue = 0.611; mean CPM = 9.623; Guanine nucleotide-binding protein G(Q) subunit alpha; Uncharacterized protein" ID="ID_791301924" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNG3: 1.17-fold Up; FDR = 0.908; PValue = 0.683; mean CPM = 0.7891; calcium channel, voltage-dependent, gamma subunit 3" ID="ID_728507249" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FASLG: 1.2-fold Down; FDR = 0.941; PValue = 0.757; mean CPM = 0.8088; Fas ligand (TNF superfamily, member 6)" ID="ID_1671571025" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016883: 1.11-fold Down; FDR = 0.97; PValue = 0.811; mean CPM = 0.8838; Uncharacterized protein" ID="ID_1874842541" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG2: 1.06-fold Up; FDR = 0.985; PValue = 0.834; mean CPM = 2.248; phospholipase C, gamma 2 (phosphatidylinositol-specific)" ID="ID_1963545979" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNA1G: 1.06-fold Down; FDR = 0.991; PValue = 0.844; mean CPM = 1.671; Uncharacterized protein" ID="ID_1112310005" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNB5: 1.04-fold Down; FDR = 1; PValue = 0.881; mean CPM = 1.533; guanine nucleotide binding protein (G protein), beta 5" ID="ID_1648787034" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNG2: 1.05-fold Up; FDR = 1; PValue = 0.915; mean CPM = 0.9147; calcium channel, voltage-dependent, gamma subunit 2" ID="ID_77999391" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAQ: No Change; FDR = 1; PValue = 0.975; mean CPM = 15.20; guanine nucleotide binding protein (G protein), q polypeptide" ID="ID_563973062" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNG4: 1.03-fold Up; FDR = 1; PValue = 0.993; mean CPM = 0.8322; calcium channel, voltage-dependent, gamma subunit 4" ID="ID_1301698570" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNG6: No Change; FDR = 1; PValue = 1; mean CPM = 0.7800; calcium channel, voltage-dependent, gamma subunit 6" ID="ID_111440375" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="MTor: FDR = 3.86e-12, PValue = 1.71e-12" ID="ID_1503597694" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TLR2: 8.94-fold Up; FDR = 6.97e-23; PValue = 1.25e-25; mean CPM = 18.41; toll-like receptor 2" ID="ID_938182160" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF1: 18.6-fold Up; FDR = 1.53e-21; PValue = 4.24e-24; mean CPM = 240.7; interferon regulatory factor 1" ID="ID_943942525" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR3: 10.3-fold Up; FDR = 1.95e-21; PValue = 5.6e-24; mean CPM = 35.70; toll-like receptor 3" ID="ID_1681048206" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF7: 14.8-fold Up; FDR = 7.66e-18; PValue = 4.82e-20; mean CPM = 11.54; Macaca mulatta interferon regulatory factor 7 (IRF7), mRNA." ID="ID_712999323" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_1524452378" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR4: 3.45-fold Up; FDR = 3.1e-09; PValue = 1.19e-10; mean CPM = 7.456; Macaca mulatta toll-like receptor 4 (TLR4), mRNA." ID="ID_1021001400" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1B: 1.64-fold Up; FDR = 1.22e-08; PValue = 5.39e-10; mean CPM = 32.96; Cyclin-dependent kinase inhibitor 1B; Uncharacterized protein" ID="ID_1948318022" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INSR: 1.93-fold Down; FDR = 1.24e-08; PValue = 5.48e-10; mean CPM = 118.3; insulin receptor" ID="ID_65292570" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_966816752" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1455109788" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_1819200542" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1: 5.76-fold Down; FDR = 6.73e-06; PValue = 6.04e-07; mean CPM = 1.536; insulin-like growth factor 1 (somatomedin C)" ID="ID_630083871" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TSC2: 1.44-fold Down; FDR = 1e-05; PValue = 9.42e-07; mean CPM = 124.0; tuberous sclerosis 2" ID="ID_1089555015" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPTOR: 1.4-fold Down; FDR = 2.58e-05; PValue = 2.69e-06; mean CPM = 53.57; regulatory associated protein of MTOR, complex 1" ID="ID_1947435546" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KLF2: 1.79-fold Down; FDR = 3.43e-05; PValue = 3.72e-06; mean CPM = 18.91; Uncharacterized protein" ID="ID_1430595221" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB2: 1.38-fold Down; FDR = 4.66e-05; PValue = 5.24e-06; mean CPM = 61.90; ribosomal protein S6 kinase, 70kDa, polypeptide 2" ID="ID_1139597054" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_778184855" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KIAA0652: 1.35-fold Up; FDR = 0.00021; PValue = 2.87e-05; mean CPM = 44.45; KIAA0652" ID="ID_67198234" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RB1CC1: 1.34-fold Up; FDR = 0.000258; PValue = 3.64e-05; mean CPM = 132.0; Uncharacterized protein" ID="ID_956307399" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTOR: 1.3-fold Down; FDR = 0.00117; PValue = 0.000201; mean CPM = 107.5; mechanistic target of rapamycin (serine/threonine kinase)" ID="ID_1460852364" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF4EBP2: 1.38-fold Down; FDR = 0.00161; PValue = 0.00029; mean CPM = 14.84; eukaryotic translation initiation factor 4E binding protein 2" ID="ID_1955761088" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1S1: 1.31-fold Down; FDR = 0.00202; PValue = 0.000375; mean CPM = 35.32; AKT1 substrate 1 (proline-rich)" ID="ID_1099744139" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SGK1: 1.36-fold Down; FDR = 0.0048; PValue = 0.00101; mean CPM = 395.0; Uncharacterized protein" ID="ID_1210177433" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR5: 1.86-fold Down; FDR = 0.00878; PValue = 0.00203; mean CPM = 3.008; toll-like receptor 5" ID="ID_765723673" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12A: 2.09-fold Up; FDR = 0.00924; PValue = 0.00215; mean CPM = 2.872; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)" ID="ID_190650151" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ULK1: 1.34-fold Down; FDR = 0.0121; PValue = 0.00293; mean CPM = 33.52; unc-51-like kinase 1 (C. elegans)" ID="ID_111805433" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1050662628" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF4EBP2: 1.75-fold Down; FDR = 0.0339; PValue = 0.00972; mean CPM = 2.255; Eukaryotic translation initiation factor 4E-binding protein 2; Uncharacterized protein" ID="ID_30296889" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR7: 1.48-fold Down; FDR = 0.0357; PValue = 0.0103; mean CPM = 13.37; chemokine (C-C motif) receptor 7" ID="ID_47087458" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_966112569" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TSC1: 1.19-fold Down; FDR = 0.0564; PValue = 0.0177; mean CPM = 38.34; tuberous sclerosis 1" ID="ID_1774663987" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF4EBP1: 1.23-fold Up; FDR = 0.0729; PValue = 0.0241; mean CPM = 40.55; eukaryotic translation initiation factor 4E binding protein 1" ID="ID_1887807893" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3A: 1.18-fold Down; FDR = 0.097; PValue = 0.0338; mean CPM = 25.14; Glycogen synthase kinase-3 alpha; Uncharacterized protein" ID="ID_1739439177" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_131741275" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTEN: 1.14-fold Up; FDR = 0.166; PValue = 0.065; mean CPM = 89.60; phosphatase and tensin homolog" ID="ID_1299383540" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHEB: 1.13-fold Up; FDR = 0.193; PValue = 0.0785; mean CPM = 118.9; Ras homolog enriched in brain" ID="ID_1373302646" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT3A: 2.28-fold Down; FDR = 0.2; PValue = 0.0823; mean CPM = 0.8811; wingless-type MMTV integration site family, member 3A" ID="ID_1121358220" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_942838772" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKAB1: 1.12-fold Up; FDR = 0.3; PValue = 0.136; mean CPM = 30.19; protein kinase, AMP-activated, beta 1 non-catalytic subunit" ID="ID_419900766" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_1389677325" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL23A: 1.39-fold Up; FDR = 0.348; PValue = 0.163; mean CPM = 4.542; interleukin 23, alpha subunit p19" ID="ID_271161389" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPKAP1: 1.1-fold Up; FDR = 0.373; PValue = 0.177; mean CPM = 55.89; mitogen-activated protein kinase associated protein 1" ID="ID_1430835409" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_523515173" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_124202397" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNB1: 1.79-fold Up; FDR = 0.731; PValue = 0.433; mean CPM = 0.8526; interferon, beta 1, fibroblast" ID="ID_1340424388" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR6: 1.07-fold Down; FDR = 0.84; PValue = 0.546; mean CPM = 7.909; toll-like receptor 6" ID="ID_1357011836" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FKBP1A: 1.04-fold Down; FDR = 0.851; PValue = 0.562; mean CPM = 209.1; Peptidyl-prolyl cis-trans isomerase" ID="ID_1364198105" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR7: 1.37-fold Down; FDR = 0.878; PValue = 0.597; mean CPM = 0.8402; toll-like receptor 7" ID="ID_218534358" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB1: 1.04-fold Up; FDR = 0.88; PValue = 0.6; mean CPM = 30.80; Uncharacterized protein" ID="ID_2125932" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12B: 1.07-fold Up; FDR = 0.983; PValue = 0.831; mean CPM = 0.8197; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)" ID="ID_1015111900" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR9: 1.01-fold Down; FDR = 1; PValue = 0.859; mean CPM = 21.45; Macaca mulatta toll-like receptor 9 (TLR9), mRNA." ID="ID_832574786" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STK11: 1.01-fold Up; FDR = 1; PValue = 0.918; mean CPM = 47.98; serine/threonine kinase 11" ID="ID_1818346062" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C12orf44: 1.01-fold Up; FDR = 1; PValue = 0.938; mean CPM = 59.62; Autophagy-related protein 101" ID="ID_1531071740" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR1: 1.02-fold Up; FDR = 1; PValue = 0.945; mean CPM = 1.221; toll-like receptor 1" ID="ID_857293566" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL10: 1.21-fold Down; FDR = 1; PValue = 0.964; mean CPM = 0.8614; interleukin 10" ID="ID_28645319" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SELL: 1.04-fold Up; FDR = 1; PValue = 0.995; mean CPM = 0.8177; Macaca mulatta selectin L (SELL), mRNA." ID="ID_1015983844" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-10: FDR = 3.86e-12, PValue = 1.71e-12" ID="ID_952929207" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="STAT2: 2.67-fold Up; FDR = 8.02e-19; PValue = 4.03e-21; mean CPM = 185.6; signal transducer and activator of transcription 2, 113kDa" ID="ID_916663470" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_835830073" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5A: 2.28-fold Up; FDR = 6.87e-14; PValue = 8.58e-16; mean CPM = 21.55; signal transducer and activator of transcription 5A" ID="ID_1727220899" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_397664972" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND3: 2.27-fold Down; FDR = 8.38e-11; PValue = 2.15e-12; mean CPM = 86.90; cyclin D3" ID="ID_444475755" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR4: 3.45-fold Up; FDR = 3.1e-09; PValue = 1.19e-10; mean CPM = 7.456; Macaca mulatta toll-like receptor 4 (TLR4), mRNA." ID="ID_1760345711" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1066995918" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD14: 2.75-fold Down; FDR = 6.54e-07; PValue = 4.46e-08; mean CPM = 5.195; CD14 molecule" ID="ID_1090508060" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L1: 1.51-fold Up; FDR = 9.13e-07; PValue = 6.52e-08; mean CPM = 66.15; Bcl-2-like protein 1; Bcl-2-like protein 1 isoform 1; Uncharacterized protein" ID="ID_1543671198" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_1268154339" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT4: 1.79-fold Up; FDR = 2.3e-05; PValue = 2.36e-06; mean CPM = 26.79; signal transducer and activator of transcription 4" ID="ID_1006701868" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HMOX1: 1.94-fold Up; FDR = 7.83e-05; PValue = 9.42e-06; mean CPM = 15.01; heme oxygenase (decycling) 1" ID="ID_1423021693" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_818605101" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TIA1: 1.35-fold Up; FDR = 0.000361; PValue = 5.3e-05; mean CPM = 39.12; TIA1 cytotoxic granule-associated RNA binding protein" ID="ID_264391270" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS3: 1.69-fold Up; FDR = 0.000994; PValue = 0.000167; mean CPM = 37.76; suppressor of cytokine signaling 3" ID="ID_1184716788" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="REL: 1.46-fold Down; FDR = 0.00272; PValue = 0.000526; mean CPM = 10.17; v-rel avian reticuloendotheliosis viral oncogene homolog" ID="ID_569439199" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYK2: 1.24-fold Down; FDR = 0.0142; PValue = 0.00354; mean CPM = 42.58; tyrosine kinase 2" ID="ID_1038578604" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BLVRA: 1.23-fold Up; FDR = 0.0288; PValue = 0.00801; mean CPM = 47.29; biliverdin reductase A" ID="ID_219798279" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIM1: 1.39-fold Down; FDR = 0.0325; PValue = 0.00926; mean CPM = 21.11; pim-1 oncogene" ID="ID_988372429" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1970434646" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELB: 1.22-fold Down; FDR = 0.0606; PValue = 0.0193; mean CPM = 26.64; v-rel reticuloendotheliosis viral oncogene homolog B" ID="ID_1710093044" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_1020786204" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT6: 1.18-fold Up; FDR = 0.0727; PValue = 0.024; mean CPM = 217.5; signal transducer and activator of transcription 6, interleukin-4 induced" ID="ID_110935018" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_219990709" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND1: 1.17-fold Up; FDR = 0.121; PValue = 0.0443; mean CPM = 867.3; cyclin D1" ID="ID_1718620729" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1A: 1.5-fold Up; FDR = 0.315; PValue = 0.144; mean CPM = 155.4; interleukin 1, alpha" ID="ID_1497791003" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND2: 1.2-fold Up; FDR = 0.335; PValue = 0.155; mean CPM = 76.91; cyclin D2" ID="ID_946497076" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL23A: 1.39-fold Up; FDR = 0.348; PValue = 0.163; mean CPM = 4.542; interleukin 23, alpha subunit p19" ID="ID_955762092" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1995907798" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL10RA: 1.55-fold Down; FDR = 0.516; PValue = 0.269; mean CPM = 0.9545; interleukin 10 receptor, alpha" ID="ID_1619127836" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_1150603382" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPKAPK2: 1.06-fold Down; FDR = 0.733; PValue = 0.435; mean CPM = 82.16; mitogen-activated protein kinase-activated protein kinase 2" ID="ID_131625907" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_804150904" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BLVRB: 1.03-fold Up; FDR = 0.908; PValue = 0.676; mean CPM = 62.92; biliverdin reductase B (flavin reductase (NADPH))" ID="ID_785088056" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADAMTS13: 1.01-fold Up; FDR = 1; PValue = 0.935; mean CPM = 5.092; ADAM metallopeptidase with thrombospondin type 1 motif, 13" ID="ID_1476473527" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL10: 1.21-fold Down; FDR = 1; PValue = 0.964; mean CPM = 0.8614; interleukin 10" ID="ID_1056546296" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Natural killer cell mediated cytotoxicity: FDR = 8.97e-12, PValue = 4.15e-12" ID="ID_246007065" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="ENSMMUP00000027180: 6.97-fold Up; FDR = 1.24e-21; PValue = 3.39e-24; mean CPM = 285.4; Uncharacterized protein" ID="ID_1008744058" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000027180: 6.97-fold Up; FDR = 1.24e-21; PValue = 3.39e-24; mean CPM = 285.4; Uncharacterized protein" ID="ID_598281795" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000005183: 4.07-fold Up; FDR = 2.87e-21; PValue = 8.51e-24; mean CPM = 164.7; Uncharacterized protein" ID="ID_1209034656" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000005183: 4.07-fold Up; FDR = 2.87e-21; PValue = 8.51e-24; mean CPM = 164.7; Uncharacterized protein" ID="ID_1105728026" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-B: 6.07-fold Up; FDR = 2.71e-19; PValue = 1.2e-21; mean CPM = 2098; Uncharacterized protein" ID="ID_1908128499" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICAM1: 24.6-fold Up; FDR = 2.39e-17; PValue = 1.64e-19; mean CPM = 232.4; intercellular adhesion molecule 1" ID="ID_54180179" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF10: 44.5-fold Up; FDR = 2.83e-16; PValue = 2.4e-18; mean CPM = 6.029; Tumor necrosis factor ligand superfamily member 10 isoform 1; Uncharacterized protein" ID="ID_232423723" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC4: 7.09-fold Down; FDR = 1.82e-12; PValue = 3.1e-14; mean CPM = 6.421; SHC (Src homology 2 domain containing) family, member 4" ID="ID_786475256" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC4: 1.85-fold Down; FDR = 1.13e-11; PValue = 2.37e-13; mean CPM = 51.58; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4" ID="ID_1529687786" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_684637019" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BID: 1.66-fold Up; FDR = 5.41e-09; PValue = 2.19e-10; mean CPM = 35.19; BH3 interacting domain death agonist" ID="ID_1232662517" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2B: 3.54-fold Up; FDR = 1.24e-07; PValue = 7.07e-09; mean CPM = 5.971; PTK2B protein tyrosine kinase 2 beta" ID="ID_402740142" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_622730543" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_334128113" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_232295384" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR2: 1.74-fold Up; FDR = 1.85e-06; PValue = 1.44e-07; mean CPM = 26.05; interferon (alpha, beta and omega) receptor 2" ID="ID_648236199" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC3: 1.68-fold Down; FDR = 2.72e-06; PValue = 2.19e-07; mean CPM = 13.98; ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)" ID="ID_1691767696" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_618964565" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF10D: 1.84-fold Down; FDR = 5.9e-05; PValue = 6.84e-06; mean CPM = 32.06; tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain" ID="ID_907637999" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ULBP3: 2.32-fold Down; FDR = 0.000296; PValue = 4.26e-05; mean CPM = 4.191; UL16 binding protein 3" ID="ID_733785695" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP3CA: 1.55-fold Up; FDR = 0.0003; PValue = 4.32e-05; mean CPM = 40.21; protein phosphatase 3, catalytic subunit, alpha isozyme" ID="ID_902357921" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC2: 4.03-fold Down; FDR = 0.000346; PValue = 5.06e-05; mean CPM = 1.347; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2" ID="ID_175694710" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD48: 2.78-fold Down; FDR = 0.000425; PValue = 6.39e-05; mean CPM = 3.161; CD48 molecule" ID="ID_143327893" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAET1E: 3.45-fold Down; FDR = 0.00045; PValue = 6.8e-05; mean CPM = 1.834; retinoic acid early transcript 1E" ID="ID_998545734" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR1: 1.31-fold Up; FDR = 0.00151; PValue = 0.000268; mean CPM = 37.77; interferon gamma receptor 1" ID="ID_799272334" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG1: 1.31-fold Down; FDR = 0.00352; PValue = 0.000707; mean CPM = 53.66; phospholipase C, gamma 1" ID="ID_1087689677" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV3: 1.82-fold Down; FDR = 0.00463; PValue = 0.000973; mean CPM = 7.044; vav 3 guanine nucleotide exchange factor" ID="ID_17124143" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR1: 1.27-fold Up; FDR = 0.0101; PValue = 0.00237; mean CPM = 82.39; Uncharacterized protein" ID="ID_651615709" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FYN: 1.22-fold Up; FDR = 0.0156; PValue = 0.00393; mean CPM = 92.94; FYN oncogene related to SRC, FGR, YES" ID="ID_1768041440" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSF2: 2.96-fold Down; FDR = 0.0174; PValue = 0.00447; mean CPM = 73.98; colony stimulating factor 2 (granulocyte-macrophage)" ID="ID_1620521115" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB2: 1.55-fold Down; FDR = 0.0187; PValue = 0.00485; mean CPM = 34.87; Integrin beta" ID="ID_1647279786" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1409028566" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AC012652.1: 1.23-fold Down; FDR = 0.0201; PValue = 0.0053; mean CPM = 33.80; Calcium-binding protein p22 (Calcium-binding protein CHP)(Calcineurin homologous protein)(Calcineurin B homolog)" ID="ID_413822576" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR2: 1.23-fold Up; FDR = 0.0258; PValue = 0.00707; mean CPM = 46.52; interferon gamma receptor 2 (interferon gamma transducer 1)" ID="ID_902708495" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFAT5: 1.21-fold Up; FDR = 0.0273; PValue = 0.00754; mean CPM = 113.0; nuclear factor of activated T-cells 5, tonicity-responsive" ID="ID_600773179" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC2: 2.96-fold Up; FDR = 0.0309; PValue = 0.00872; mean CPM = 0.9737; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)" ID="ID_1432246003" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KRAS: 1.35-fold Down; FDR = 0.0401; PValue = 0.0119; mean CPM = 13.10; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog" ID="ID_1141872084" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NRAS: 1.2-fold Down; FDR = 0.0546; PValue = 0.017; mean CPM = 32.39; neuroblastoma RAS viral (v-ras) oncogene homolog" ID="ID_1989288258" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_1998572423" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS2: 1.17-fold Up; FDR = 0.1; PValue = 0.0353; mean CPM = 31.79; son of sevenless homolog 2 (Drosophila)" ID="ID_347330619" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HCST: 1.47-fold Down; FDR = 0.129; PValue = 0.0478; mean CPM = 2.995; hematopoietic cell signal transducer" ID="ID_1227611308" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAET1G: 1.58-fold Down; FDR = 0.143; PValue = 0.0544; mean CPM = 1.944; retinoic acid early transcript 1G" ID="ID_481532600" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC2: 1.34-fold Down; FDR = 0.191; PValue = 0.0774; mean CPM = 7.313; SHC (Src homology 2 domain containing) transforming protein 2" ID="ID_1554101244" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_122307410" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_1666919308" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BRAF: 1.14-fold Down; FDR = 0.228; PValue = 0.0964; mean CPM = 24.98; v-raf murine sarcoma viral oncogene homolog B1" ID="ID_1915613958" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAT: 1.44-fold Down; FDR = 0.234; PValue = 0.0996; mean CPM = 1.871; linker for activation of T cells" ID="ID_764192714" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FCGR3A: 1.84-fold Down; FDR = 0.245; PValue = 0.106; mean CPM = 1.030; Fc fragment of IgG, low affinity IIIa, receptor (CD16a)" ID="ID_556221668" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_1970700673" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF10B: 1.13-fold Down; FDR = 0.343; PValue = 0.16; mean CPM = 40.59; tumor necrosis factor receptor superfamily, member 10b" ID="ID_1628864141" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MICB: 1.11-fold Down; FDR = 0.35; PValue = 0.164; mean CPM = 30.64; Macaca mulatta MHC class I polypeptide-related sequence B (MICB), mRNA." ID="ID_1736678018" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MICB: 1.11-fold Down; FDR = 0.35; PValue = 0.164; mean CPM = 30.64; Macaca mulatta MHC class I polypeptide-related sequence B (MICB), mRNA." ID="ID_1777801787" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_415832898" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_434505060" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_443108169" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC1: 1.11-fold Down; FDR = 0.457; PValue = 0.23; mean CPM = 19.06; Uncharacterized protein" ID="ID_1275161073" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LCP2: 1.4-fold Up; FDR = 0.496; PValue = 0.256; mean CPM = 1.322; Uncharacterized protein" ID="ID_1444455157" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP3CB: 1.08-fold Up; FDR = 0.514; PValue = 0.268; mean CPM = 76.44; protein phosphatase 3, catalytic subunit, beta isozyme" ID="ID_1897699412" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_307872440" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC3: 1.37-fold Down; FDR = 0.584; PValue = 0.318; mean CPM = 1.193; SHC-transforming protein 3; Uncharacterized protein" ID="ID_728610239" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCG: 1.47-fold Down; FDR = 0.609; PValue = 0.336; mean CPM = 0.9297; protein kinase C, gamma" ID="ID_363090586" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD247: 1.43-fold Down; FDR = 0.695; PValue = 0.404; mean CPM = 0.9076; Macaca mulatta CD247 molecule (CD247), mRNA." ID="ID_1837528060" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCB: 1.86-fold Up; FDR = 0.727; PValue = 0.43; mean CPM = 0.8705; protein kinase C, beta" ID="ID_778540116" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNB1: 1.79-fold Up; FDR = 0.731; PValue = 0.433; mean CPM = 0.8526; interferon, beta 1, fibroblast" ID="ID_103012211" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF10A: 1.06-fold Down; FDR = 0.732; PValue = 0.434; mean CPM = 42.75; tumor necrosis factor receptor superfamily, member 10a" ID="ID_1829999384" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_586200085" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000005271: 1.36-fold Down; FDR = 0.776; PValue = 0.474; mean CPM = 0.8901; Uncharacterized protein" ID="ID_1433501093" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000005271: 1.36-fold Down; FDR = 0.776; PValue = 0.474; mean CPM = 0.8901; Uncharacterized protein" ID="ID_1470765824" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000005271: 1.36-fold Down; FDR = 0.776; PValue = 0.474; mean CPM = 0.8901; Uncharacterized protein" ID="ID_1426801122" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA6: 1.41-fold Down; FDR = 0.807; PValue = 0.504; mean CPM = 0.8019; interferon, alpha 6" ID="ID_1141291216" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYROBP: 1.33-fold Up; FDR = 0.819; PValue = 0.518; mean CPM = 0.8940; TYRO protein tyrosine kinase binding protein" ID="ID_1825873141" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GZMB: 1.43-fold Up; FDR = 0.83; PValue = 0.532; mean CPM = 0.7972; granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)" ID="ID_472475462" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCR3: 1.4-fold Down; FDR = 0.832; PValue = 0.535; mean CPM = 0.8018; Natural cytotoxicity triggering receptor 3 Precursor (Natural killer cell p30-related protein)(NK-p30)(NKp30)(Activating natural killer receptor p30)(CD337 antigen)" ID="ID_1971142748" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRF1: 1.75-fold Up; FDR = 0.841; PValue = 0.548; mean CPM = 0.8583; perforin 1 (pore forming protein)" ID="ID_982063526" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICAM2: 1.26-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 0.9289; intercellular adhesion molecule 2" ID="ID_106629748" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV1: 1.25-fold Down; FDR = 0.858; PValue = 0.572; mean CPM = 0.9515; vav 1 guanine nucleotide exchange factor" ID="ID_756664146" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZAP70: 1.25-fold Down; FDR = 0.872; PValue = 0.59; mean CPM = 0.8996; zeta-chain (TCR) associated protein kinase 70kDa" ID="ID_582899331" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1358608432" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_1395118940" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_99768163" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KLRC1: 1.14-fold Down; FDR = 0.903; PValue = 0.653; mean CPM = 1.817; killer cell lectin-like receptor subfamily C, member 1" ID="ID_1763269748" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCR2: 1.15-fold Up; FDR = 0.906; PValue = 0.672; mean CPM = 0.7904; natural cytotoxicity triggering receptor 2" ID="ID_1011643319" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ULBP1: 1.18-fold Up; FDR = 0.907; PValue = 0.675; mean CPM = 1.000; UL16 binding protein 1" ID="ID_1416321057" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA13: 1.13-fold Up; FDR = 0.908; PValue = 0.677; mean CPM = 0.7960; interferon, alpha 13" ID="ID_1319977547" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA8: 1.13-fold Down; FDR = 0.911; PValue = 0.702; mean CPM = 0.7910; interferon, alpha 8" ID="ID_204245659" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK1: 1.03-fold Down; FDR = 0.911; PValue = 0.705; mean CPM = 18.65; p21 protein (Cdc42/Rac)-activated kinase 1" ID="ID_374200133" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FASLG: 1.2-fold Down; FDR = 0.941; PValue = 0.757; mean CPM = 0.8088; Fas ligand (TNF superfamily, member 6)" ID="ID_1543947550" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AC130454.2: 1.18-fold Up; FDR = 0.942; PValue = 0.76; mean CPM = 0.8360; Calcineurin B homologous protein 2 (Hepatocellular carcinoma-associated antigen 520)" ID="ID_955346604" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_836399273" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC3: 1.03-fold Down; FDR = 0.952; PValue = 0.78; mean CPM = 13.31; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3" ID="ID_1573260258" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA14: 1.22-fold Up; FDR = 0.965; PValue = 0.802; mean CPM = 0.8654; interferon, alpha 14" ID="ID_232771225" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_850134976" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA4: 1.28-fold Down; FDR = 0.983; PValue = 0.829; mean CPM = 0.8584; interferon, alpha 4" ID="ID_1495984944" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG2: 1.06-fold Up; FDR = 0.985; PValue = 0.834; mean CPM = 2.248; phospholipase C, gamma 2 (phosphatidylinositol-specific)" ID="ID_773079702" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KLRK1: 1.17-fold Up; FDR = 0.995; PValue = 0.85; mean CPM = 0.8212; killer cell lectin-like receptor subfamily K, member 1" ID="ID_1468554858" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD244: 1.12-fold Up; FDR = 1; PValue = 0.874; mean CPM = 0.8195; CD244 molecule, natural killer cell receptor 2B4" ID="ID_686180768" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAL: 1.03-fold Up; FDR = 1; PValue = 0.95; mean CPM = 1.035; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)" ID="ID_334997427" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV2: No Change; FDR = 1; PValue = 0.976; mean CPM = 25.65; vav 2 guanine nucleotide exchange factor" ID="ID_1301002234" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SYK: 1.11-fold Up; FDR = 1; PValue = 0.977; mean CPM = 0.8420; spleen tyrosine kinase" ID="ID_1316369557" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SH2D1B: 1.05-fold Up; FDR = 1; PValue = 0.989; mean CPM = 0.7990; SH2 domain containing 1B" ID="ID_220791818" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA1: No Change; FDR = 1; PValue = 0.998; mean CPM = 0.8014; interferon, alpha 1" ID="ID_923350172" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KLRD1: No Change; FDR = 1; PValue = 1; mean CPM = 0.7825; Macaca mulatta killer cell lectin-like receptor subfamily D, member 1 (KLRD1), mRNA." ID="ID_422424387" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SH2D1A: No Change; FDR = 1; PValue = 1; mean CPM = 0.7843; SH2 domain containing 1A" ID="ID_397950274" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="PI3K: FDR = 1.55e-11, PValue = 7.45e-12" ID="ID_920912280" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="FGF1: 5.05-fold Down; FDR = 8.21e-14; PValue = 1.05e-15; mean CPM = 19.54; fibroblast growth factor 1 (acidic)" ID="ID_371700727" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRS1: 2.78-fold Up; FDR = 7.67e-09; PValue = 3.19e-10; mean CPM = 26.55; Uncharacterized protein" ID="ID_1160087285" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF2: 2.42-fold Up; FDR = 9.98e-09; PValue = 4.31e-10; mean CPM = 134.8; fibroblast growth factor 2 (basic)" ID="ID_552119214" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGFR2: 3.45-fold Down; FDR = 1.04e-08; PValue = 4.53e-10; mean CPM = 5.064; fibroblast growth factor receptor 2" ID="ID_191298106" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INSR: 1.93-fold Down; FDR = 1.24e-08; PValue = 5.48e-10; mean CPM = 118.3; insulin receptor" ID="ID_1940405230" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_941081991" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1547104530" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGFR3: 3.85-fold Down; FDR = 2.66e-06; PValue = 2.13e-07; mean CPM = 2.800; fibroblast growth factor receptor 3" ID="ID_802056347" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FRS2: 1.17-fold Up; FDR = 0.105; PValue = 0.0373; mean CPM = 37.92; fibroblast growth factor receptor substrate 2" ID="ID_1528707056" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGFR1: 1.15-fold Down; FDR = 0.139; PValue = 0.0525; mean CPM = 89.41; fibroblast growth factor receptor 1" ID="ID_78394432" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF23: 2.01-fold Down; FDR = 0.188; PValue = 0.0759; mean CPM = 0.9718; fibroblast growth factor 23" ID="ID_1488206558" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1148544215" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF10: 1.55-fold Down; FDR = 0.257; PValue = 0.112; mean CPM = 3.488; fibroblast growth factor 10" ID="ID_862548606" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1753974331" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DOK1: 1.12-fold Down; FDR = 0.406; PValue = 0.198; mean CPM = 92.16; docking protein 1, 62kDa (downstream of tyrosine kinase 1)" ID="ID_1782012564" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_1816475721" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF18: 1.55-fold Down; FDR = 0.548; PValue = 0.293; mean CPM = 0.9359; fibroblast growth factor 18" ID="ID_1006547346" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GAB1: 1.1-fold Up; FDR = 0.635; PValue = 0.356; mean CPM = 14.59; GRB2-associated binding protein 1" ID="ID_302059844" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF5: 1.1-fold Down; FDR = 0.646; PValue = 0.364; mean CPM = 54.02; fibroblast growth factor 5" ID="ID_1458642049" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF9: 1.77-fold Up; FDR = 0.74; PValue = 0.441; mean CPM = 0.8485; fibroblast growth factor 9 (glia-activating factor)" ID="ID_156901493" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF8: 1.75-fold Down; FDR = 0.783; PValue = 0.48; mean CPM = 0.8245; Uncharacterized protein" ID="ID_413096096" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KL: 1.4-fold Up; FDR = 0.849; PValue = 0.559; mean CPM = 0.8285; klotho" ID="ID_1784788821" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF3: 1.22-fold Down; FDR = 0.903; PValue = 0.641; mean CPM = 0.7938; fibroblast growth factor 3 (murine mammary tumor virus integration site (v-int-2) oncogene homolog)" ID="ID_1677974394" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF17: 1.34-fold Down; FDR = 0.903; PValue = 0.662; mean CPM = 0.8230; fibroblast growth factor 17" ID="ID_1380151522" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF19: 1.33-fold Down; FDR = 0.921; PValue = 0.724; mean CPM = 0.8101; fibroblast growth factor 19" ID="ID_1151198139" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF6: 1.15-fold Up; FDR = 0.948; PValue = 0.773; mean CPM = 0.8082; fibroblast growth factor 6" ID="ID_385549839" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR9: 1.01-fold Down; FDR = 1; PValue = 0.859; mean CPM = 21.45; Macaca mulatta toll-like receptor 9 (TLR9), mRNA." ID="ID_1297803299" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R4: 1.01-fold Down; FDR = 1; PValue = 0.913; mean CPM = 41.33; phosphoinositide-3-kinase, regulatory subunit 4" ID="ID_1337440209" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF20: No Change; FDR = 1; PValue = 1; mean CPM = 0.7796; fibroblast growth factor 20" ID="ID_301707619" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="General Jak/STAT: FDR = 4.09e-11, PValue = 2.04e-11" ID="ID_220236228" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="IRF9: 3.85-fold Up; FDR = 2.6e-19; PValue = 1.12e-21; mean CPM = 106.4; interferon regulatory factor 9" ID="ID_1554438192" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT2: 2.67-fold Up; FDR = 8.02e-19; PValue = 4.03e-21; mean CPM = 185.6; signal transducer and activator of transcription 2, 113kDa" ID="ID_151549695" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_327591620" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1181043991" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL15: 17.3-fold Up; FDR = 2.78e-17; PValue = 1.92e-19; mean CPM = 5.103; Macaca mulatta interleukin 15 (IL15), mRNA." ID="ID_507556523" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL15RA: 19.4-fold Up; FDR = 4.04e-17; PValue = 2.89e-19; mean CPM = 5.291; interleukin 15 receptor, alpha" ID="ID_1225778087" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5A: 2.28-fold Up; FDR = 6.87e-14; PValue = 8.58e-16; mean CPM = 21.55; signal transducer and activator of transcription 5A" ID="ID_1520257325" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPRY1: 3.01-fold Up; FDR = 7.75e-14; PValue = 9.87e-16; mean CPM = 27.88; sprouty homolog 1, antagonist of FGF signaling (Drosophila)" ID="ID_1925743974" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL7: 9.03-fold Up; FDR = 1.39e-13; PValue = 1.9e-15; mean CPM = 5.288; interleukin 7" ID="ID_135275893" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_1027392615" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND3: 2.27-fold Down; FDR = 8.38e-11; PValue = 2.15e-12; mean CPM = 86.90; cyclin D3" ID="ID_1087307930" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIAS3: 1.63-fold Down; FDR = 2.24e-10; PValue = 6.51e-12; mean CPM = 53.00; protein inhibitor of activated STAT, 3" ID="ID_596644745" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPRY4: 2.68-fold Down; FDR = 2.32e-10; PValue = 6.78e-12; mean CPM = 12.79; sprouty homolog 4 (Drosophila)" ID="ID_394432610" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL13RA1: 1.73-fold Up; FDR = 1.81e-09; PValue = 6.5e-11; mean CPM = 42.50; interleukin 13 receptor, alpha 1" ID="ID_1352065039" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CNTF: 4.71-fold Down; FDR = 3.15e-09; PValue = 1.21e-10; mean CPM = 2.528; ciliary neurotrophic factor" ID="ID_1183900921" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_872019767" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL6ST: 1.78-fold Up; FDR = 1.86e-08; PValue = 8.65e-10; mean CPM = 437.6; interleukin 6 signal transducer (gp130, oncostatin M receptor)" ID="ID_640993532" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL11RA: 1.66-fold Down; FDR = 1.74e-07; PValue = 1.02e-08; mean CPM = 33.61; interleukin 11 receptor, alpha" ID="ID_1359546418" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_460502650" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L1: 1.51-fold Up; FDR = 9.13e-07; PValue = 6.52e-08; mean CPM = 66.15; Bcl-2-like protein 1; Bcl-2-like protein 1 isoform 1; Uncharacterized protein" ID="ID_1953211263" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_905004951" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_1684646489" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR2: 1.74-fold Up; FDR = 1.85e-06; PValue = 1.44e-07; mean CPM = 26.05; interferon (alpha, beta and omega) receptor 2" ID="ID_1940114084" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_698424171" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="OSMR: 1.49-fold Up; FDR = 1.63e-05; PValue = 1.62e-06; mean CPM = 180.8; Uncharacterized protein" ID="ID_1144526766" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT4: 1.79-fold Up; FDR = 2.3e-05; PValue = 2.36e-06; mean CPM = 26.79; signal transducer and activator of transcription 4" ID="ID_1370240444" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS5: 1.38-fold Up; FDR = 4.45e-05; PValue = 4.96e-06; mean CPM = 88.27; suppressor of cytokine signaling 5" ID="ID_651720834" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL20RB: 3.26-fold Up; FDR = 6.13e-05; PValue = 7.16e-06; mean CPM = 4.526; interleukin 20 receptor beta" ID="ID_1839787854" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL6R: 3.84-fold Down; FDR = 6.68e-05; PValue = 7.89e-06; mean CPM = 4.840; interleukin 6 receptor" ID="ID_659696747" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LIFR: 1.59-fold Up; FDR = 0.000539; PValue = 8.35e-05; mean CPM = 35.74; leukemia inhibitory factor receptor alpha" ID="ID_601940636" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS3: 1.69-fold Up; FDR = 0.000994; PValue = 0.000167; mean CPM = 37.76; suppressor of cytokine signaling 3" ID="ID_927258106" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CISH: 1.95-fold Up; FDR = 0.00116; PValue = 0.0002; mean CPM = 5.083; cytokine inducible SH2-containing protein" ID="ID_307659951" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR1: 1.31-fold Up; FDR = 0.00151; PValue = 0.000268; mean CPM = 37.77; interferon gamma receptor 1" ID="ID_1565408069" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAM2: 1.3-fold Up; FDR = 0.00163; PValue = 0.000295; mean CPM = 50.32; signal transducing adaptor molecule (SH3 domain and ITAM motif) 2" ID="ID_27481407" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK3: 2.31-fold Up; FDR = 0.00186; PValue = 0.000342; mean CPM = 2.154; Janus kinase 3" ID="ID_901821138" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTF1: 1.87-fold Up; FDR = 0.0019; PValue = 0.000351; mean CPM = 3.623; cardiotrophin 1" ID="ID_29712068" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="OSM: 4.6-fold Down; FDR = 0.00251; PValue = 0.00048; mean CPM = 0.9104; oncostatin M" ID="ID_1122383497" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIAS1: 1.3-fold Up; FDR = 0.00259; PValue = 0.000498; mean CPM = 29.99; protein inhibitor of activated STAT, 1" ID="ID_282462554" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CBLC: 2.87-fold Down; FDR = 0.00443; PValue = 0.000923; mean CPM = 3.105; Cas-Br-M (murine) ecotropic retroviral transforming sequence c" ID="ID_679042527" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12A: 2.09-fold Up; FDR = 0.00924; PValue = 0.00215; mean CPM = 2.872; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)" ID="ID_1067967328" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLCF1: 1.4-fold Down; FDR = 0.00977; PValue = 0.00229; mean CPM = 21.80; cardiotrophin-like cytokine factor 1" ID="ID_1100053556" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR1: 1.27-fold Up; FDR = 0.0101; PValue = 0.00237; mean CPM = 82.39; Uncharacterized protein" ID="ID_971613422" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EPOR: 1.56-fold Down; FDR = 0.014; PValue = 0.00347; mean CPM = 3.898; erythropoietin receptor" ID="ID_185293490" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYK2: 1.24-fold Down; FDR = 0.0142; PValue = 0.00354; mean CPM = 42.58; tyrosine kinase 2" ID="ID_615956615" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSF2: 2.96-fold Down; FDR = 0.0174; PValue = 0.00447; mean CPM = 73.98; colony stimulating factor 2 (granulocyte-macrophage)" ID="ID_1355463340" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS2: 1.31-fold Down; FDR = 0.0188; PValue = 0.0049; mean CPM = 35.29; suppressor of cytokine signaling 2" ID="ID_773852662" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRLF2: 2.92-fold Down; FDR = 0.0202; PValue = 0.00531; mean CPM = 1.758; cytokine receptor-like factor 2" ID="ID_127305022" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL20RA: 2.25-fold Up; FDR = 0.0255; PValue = 0.00695; mean CPM = 1.386; interleukin 20 receptor, alpha" ID="ID_1721399946" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1924820933" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR2: 1.23-fold Up; FDR = 0.0258; PValue = 0.00707; mean CPM = 46.52; interferon gamma receptor 2 (interferon gamma transducer 1)" ID="ID_834048926" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIM1: 1.39-fold Down; FDR = 0.0325; PValue = 0.00926; mean CPM = 21.11; pim-1 oncogene" ID="ID_941585375" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LEP: 1.67-fold Down; FDR = 0.0401; PValue = 0.0118; mean CPM = 63.70; leptin" ID="ID_563555242" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TPO: 2.96-fold Down; FDR = 0.0533; PValue = 0.0166; mean CPM = 1.110; thyroid peroxidase" ID="ID_69041168" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIAS4: 1.22-fold Down; FDR = 0.0547; PValue = 0.0171; mean CPM = 18.45; protein inhibitor of activated STAT, 4" ID="ID_334807680" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_1915410471" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL7R: 1.76-fold Down; FDR = 0.0698; PValue = 0.0229; mean CPM = 3.067; interleukin 7 receptor" ID="ID_413499794" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSF3: 2.55-fold Up; FDR = 0.0701; PValue = 0.023; mean CPM = 72.12; colony stimulating factor 3 (granulocyte)" ID="ID_1084285300" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT6: 1.18-fold Up; FDR = 0.0727; PValue = 0.024; mean CPM = 217.5; signal transducer and activator of transcription 6, interleukin-4 induced" ID="ID_1747654530" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL13RA2: 2.13-fold Up; FDR = 0.0909; PValue = 0.0313; mean CPM = 1.485; Interleukin-13 receptor subunit alpha-2; Uncharacterized protein" ID="ID_1951329086" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_1502639146" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS2: 1.17-fold Up; FDR = 0.1; PValue = 0.0353; mean CPM = 31.79; son of sevenless homolog 2 (Drosophila)" ID="ID_903416427" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL28RA: 2.43-fold Down; FDR = 0.115; PValue = 0.0414; mean CPM = 0.9001; interleukin 28 receptor, alpha (interferon, lambda receptor)" ID="ID_1378339067" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND1: 1.17-fold Up; FDR = 0.121; PValue = 0.0443; mean CPM = 867.3; cyclin D1" ID="ID_1913913322" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPRED1: 1.15-fold Up; FDR = 0.143; PValue = 0.0543; mean CPM = 41.74; sprouty-related, EVH1 domain containing 1" ID="ID_417898258" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPRY3: 1.5-fold Up; FDR = 0.161; PValue = 0.0627; mean CPM = 2.641; sprouty homolog 3 (Drosophila)" ID="ID_656557749" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_622849742" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_1810418343" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12RB2: 1.42-fold Down; FDR = 0.299; PValue = 0.135; mean CPM = 1.728; interleukin 12 receptor, beta 2" ID="ID_1824235153" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EP300: 1.11-fold Up; FDR = 0.312; PValue = 0.142; mean CPM = 162.8; E1A binding protein p300" ID="ID_1564497187" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_458721173" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND2: 1.2-fold Up; FDR = 0.335; PValue = 0.155; mean CPM = 76.91; cyclin D2" ID="ID_471483502" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL23A: 1.39-fold Up; FDR = 0.348; PValue = 0.163; mean CPM = 4.542; interleukin 23, alpha subunit p19" ID="ID_1589234702" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GHR: 1.23-fold Up; FDR = 0.369; PValue = 0.175; mean CPM = 6.312; growth hormone receptor" ID="ID_939851265" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1665925444" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EPO: 1.77-fold Up; FDR = 0.39; PValue = 0.188; mean CPM = 0.9174; Macaca mulatta erythropoietin (EPO), mRNA." ID="ID_1017260890" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MPL: 1.3-fold Down; FDR = 0.411; PValue = 0.201; mean CPM = 2.108; myeloproliferative leukemia virus oncogene" ID="ID_1872042353" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CNTFR: 1.67-fold Down; FDR = 0.435; PValue = 0.216; mean CPM = 1.033; Uncharacterized protein" ID="ID_834445599" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_190444196" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL19: 1.65-fold Down; FDR = 0.455; PValue = 0.228; mean CPM = 0.9514; interleukin 19" ID="ID_1384961789" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LEPR: 1.52-fold Down; FDR = 0.489; PValue = 0.251; mean CPM = 1.051; leptin receptor" ID="ID_63578929" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPRY2: 1.09-fold Down; FDR = 0.515; PValue = 0.269; mean CPM = 27.90; sprouty homolog 2 (Drosophila)" ID="ID_506023591" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL10RA: 1.55-fold Down; FDR = 0.516; PValue = 0.269; mean CPM = 0.9545; interleukin 10 receptor, alpha" ID="ID_559568415" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_910985883" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL21R: 1.56-fold Down; FDR = 0.534; PValue = 0.282; mean CPM = 1.021; interleukin 21 receptor" ID="ID_1017014654" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL24: 1.37-fold Down; FDR = 0.563; PValue = 0.303; mean CPM = 26.16; interleukin 24" ID="ID_1447104924" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL9R: 2.21-fold Down; FDR = 0.63; PValue = 0.352; mean CPM = 0.8661; interleukin 9 receptor" ID="ID_1246581698" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNE: 1.18-fold Up; FDR = 0.646; PValue = 0.364; mean CPM = 2.614; interferon, epsilon" ID="ID_1926733923" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LIF: 1.07-fold Down; FDR = 0.702; PValue = 0.409; mean CPM = 148.6; leukemia inhibitory factor (cholinergic differentiation factor)" ID="ID_1667083601" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12RB1: 1.39-fold Up; FDR = 0.703; PValue = 0.41; mean CPM = 0.9665; interleukin 12 receptor, beta 1" ID="ID_1002991785" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL11: 1.13-fold Up; FDR = 0.715; PValue = 0.42; mean CPM = 128.8; interleukin 11" ID="ID_660054166" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNB1: 1.79-fold Up; FDR = 0.731; PValue = 0.433; mean CPM = 0.8526; interferon, beta 1, fibroblast" ID="ID_1690684244" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL4R: 1.05-fold Down; FDR = 0.803; PValue = 0.499; mean CPM = 193.5; interleukin 4 receptor" ID="ID_566181141" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIAS2: 1.06-fold Down; FDR = 0.807; PValue = 0.503; mean CPM = 19.53; protein inhibitor of activated STAT, 2" ID="ID_1621465887" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA6: 1.41-fold Down; FDR = 0.807; PValue = 0.504; mean CPM = 0.8019; interferon, alpha 6" ID="ID_286081293" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CBL: 1.05-fold Down; FDR = 0.824; PValue = 0.524; mean CPM = 51.06; Cas-Br-M (murine) ecotropic retroviral transforming sequence" ID="ID_1089424844" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL28B: 1.53-fold Down; FDR = 0.836; PValue = 0.541; mean CPM = 0.8237; interleukin 28B (interferon, lambda 3)" ID="ID_1374169442" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL22RA1: 1.26-fold Up; FDR = 0.846; PValue = 0.555; mean CPM = 0.9674; interleukin 22 receptor, alpha 1" ID="ID_1913596809" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS7: 1.07-fold Down; FDR = 0.847; PValue = 0.556; mean CPM = 7.514; suppressor of cytokine signaling 7" ID="ID_791199896" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CBLB: 1.04-fold Down; FDR = 0.859; PValue = 0.574; mean CPM = 64.59; Cas-Br-M (murine) ecotropic retroviral transforming sequence b" ID="ID_536137391" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL29: 1.38-fold Down; FDR = 0.898; PValue = 0.624; mean CPM = 0.8355; interleukin 29 (interferon, lambda 1)" ID="ID_1602012132" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAM: 1.04-fold Down; FDR = 0.899; PValue = 0.627; mean CPM = 29.84; signal transducing adaptor molecule (SH3 domain and ITAM motif) 1" ID="ID_961952236" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL22RA2: 1.2-fold Down; FDR = 0.899; PValue = 0.629; mean CPM = 0.7954; interleukin 22 receptor, alpha 2" ID="ID_1953304662" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_1402410800" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSF2RA: 1.19-fold Up; FDR = 0.906; PValue = 0.666; mean CPM = 0.9897; colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)" ID="ID_347597402" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA13: 1.13-fold Up; FDR = 0.908; PValue = 0.677; mean CPM = 0.7960; interferon, alpha 13" ID="ID_1041045408" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA8: 1.13-fold Down; FDR = 0.911; PValue = 0.702; mean CPM = 0.7910; interferon, alpha 8" ID="ID_786521830" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL9: 1.14-fold Up; FDR = 0.911; PValue = 0.705; mean CPM = 0.7910; interleukin 9" ID="ID_632333119" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSF3R: 1.13-fold Down; FDR = 0.921; PValue = 0.723; mean CPM = 0.9331; colony stimulating factor 3 receptor (granulocyte)" ID="ID_807714747" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS4: 1.03-fold Up; FDR = 0.921; PValue = 0.724; mean CPM = 17.28; suppressor of cytokine signaling 4" ID="ID_164081349" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL22: 1.33-fold Down; FDR = 0.928; PValue = 0.735; mean CPM = 0.8193; interleukin 22" ID="ID_117005149" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL4: 1.27-fold Down; FDR = 0.933; PValue = 0.745; mean CPM = 0.8077; interleukin 4" ID="ID_999788175" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2RA: 1.08-fold Up; FDR = 0.945; PValue = 0.766; mean CPM = 0.8493; interleukin 2 receptor, alpha" ID="ID_1635751283" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL21: 1.04-fold Up; FDR = 0.948; PValue = 0.773; mean CPM = 0.8164; interleukin 21" ID="ID_709369700" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL20: 1.22-fold Up; FDR = 0.951; PValue = 0.779; mean CPM = 0.8273; interleukin 20" ID="ID_1639019859" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL5RA: 1.1-fold Up; FDR = 0.958; PValue = 0.791; mean CPM = 0.8108; interleukin 5 receptor, alpha" ID="ID_1783433283" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA14: 1.22-fold Up; FDR = 0.965; PValue = 0.802; mean CPM = 0.8654; interferon, alpha 14" ID="ID_1351411402" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL13: 1.05-fold Up; FDR = 0.967; PValue = 0.805; mean CPM = 0.8212; interleukin 13" ID="ID_1095617560" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA4: 1.28-fold Down; FDR = 0.983; PValue = 0.829; mean CPM = 0.8584; interferon, alpha 4" ID="ID_1355290420" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12B: 1.07-fold Up; FDR = 0.983; PValue = 0.831; mean CPM = 0.8197; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)" ID="ID_461465702" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREBBP: 1.01-fold Down; FDR = 0.993; PValue = 0.847; mean CPM = 137.7; CREB binding protein" ID="ID_1734582020" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL5: 1.05-fold Down; FDR = 1; PValue = 0.862; mean CPM = 1.367; interleukin 5 (colony-stimulating factor, eosinophil)" ID="ID_1912884711" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRLR: 1.06-fold Down; FDR = 1; PValue = 0.889; mean CPM = 1.017; prolactin receptor" ID="ID_318200701" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL3: 1.17-fold Down; FDR = 1; PValue = 0.9; mean CPM = 0.8325; Macaca mulatta interleukin 3 (colony-stimulating factor, multiple) (IL3), mRNA." ID="ID_71315692" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL10: 1.21-fold Down; FDR = 1; PValue = 0.964; mean CPM = 0.8614; interleukin 10" ID="ID_1292314061" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL23R: 1.05-fold Down; FDR = 1; PValue = 0.994; mean CPM = 0.7958; interleukin 23 receptor" ID="ID_549269681" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2: 1.03-fold Up; FDR = 1; PValue = 0.998; mean CPM = 0.7974; interleukin 2" ID="ID_1996627821" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA1: No Change; FDR = 1; PValue = 0.998; mean CPM = 0.8014; interferon, alpha 1" ID="ID_1991236294" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL26: No Change; FDR = 1; PValue = 1; mean CPM = 0.7833; interleukin 26" ID="ID_1196946047" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNK: No Change; FDR = 1; PValue = 1; mean CPM = 0.7868; interferon, kappa" ID="ID_1329715442" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNW1: No Change; FDR = 1; PValue = 1; mean CPM = 0.7851; interferon, omega 1" ID="ID_1784963950" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-9: FDR = 8.3e-11, PValue = 4.3e-11" ID="ID_1340134608" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="STAT2: 2.67-fold Up; FDR = 8.02e-19; PValue = 4.03e-21; mean CPM = 185.6; signal transducer and activator of transcription 2, 113kDa" ID="ID_1291112222" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_137435361" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5A: 2.28-fold Up; FDR = 6.87e-14; PValue = 8.58e-16; mean CPM = 21.55; signal transducer and activator of transcription 5A" ID="ID_1566085281" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_1739243070" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_745132113" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1350055987" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1720149321" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1B: 2.24-fold Up; FDR = 2.68e-06; PValue = 2.16e-07; mean CPM = 19.44; tumor necrosis factor receptor superfamily, member 1B" ID="ID_201313414" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_1100432373" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1668712497" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT4: 1.79-fold Up; FDR = 2.3e-05; PValue = 2.36e-06; mean CPM = 26.79; signal transducer and activator of transcription 4" ID="ID_117255908" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS5: 1.38-fold Up; FDR = 4.45e-05; PValue = 4.96e-06; mean CPM = 88.27; suppressor of cytokine signaling 5" ID="ID_1180956298" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_784837334" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS3: 1.69-fold Up; FDR = 0.000994; PValue = 0.000167; mean CPM = 37.76; suppressor of cytokine signaling 3" ID="ID_1127076844" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CISH: 1.95-fold Up; FDR = 0.00116; PValue = 0.0002; mean CPM = 5.083; cytokine inducible SH2-containing protein" ID="ID_1571715962" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK3: 2.31-fold Up; FDR = 0.00186; PValue = 0.000342; mean CPM = 2.154; Janus kinase 3" ID="ID_518843670" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="REL: 1.46-fold Down; FDR = 0.00272; PValue = 0.000526; mean CPM = 10.17; v-rel avian reticuloendotheliosis viral oncogene homolog" ID="ID_818500619" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS2: 1.31-fold Down; FDR = 0.0188; PValue = 0.0049; mean CPM = 35.29; suppressor of cytokine signaling 2" ID="ID_1270112654" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_801789318" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_819059077" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL3: 1.25-fold Up; FDR = 0.0559; PValue = 0.0175; mean CPM = 16.96; B-cell CLL/lymphoma 3" ID="ID_1052775403" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELB: 1.22-fold Down; FDR = 0.0606; PValue = 0.0193; mean CPM = 26.64; v-rel reticuloendotheliosis viral oncogene homolog B" ID="ID_610039499" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_212079741" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1905075331" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS6: 1.13-fold Up; FDR = 0.248; PValue = 0.107; mean CPM = 30.93; suppressor of cytokine signaling 6" ID="ID_586231983" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1A: 1.11-fold Up; FDR = 0.297; PValue = 0.134; mean CPM = 134.7; tumor necrosis factor receptor superfamily, member 1A" ID="ID_789738101" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_1918200831" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1244964588" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3C2B: 1.17-fold Down; FDR = 0.406; PValue = 0.198; mean CPM = 6.381; phosphoinositide-3-kinase, class 2, beta polypeptide" ID="ID_227753638" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_473017647" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_22676377" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL9R: 2.21-fold Down; FDR = 0.63; PValue = 0.352; mean CPM = 0.8661; interleukin 9 receptor" ID="ID_1968228051" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1196246543" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_396456761" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL9: 1.14-fold Up; FDR = 0.911; PValue = 0.705; mean CPM = 0.7910; interleukin 9" ID="ID_602964277" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK9: 1.02-fold Down; FDR = 0.942; PValue = 0.76; mean CPM = 37.82; cyclin-dependent kinase 9" ID="ID_304884886" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3C2A: 1.02-fold Up; FDR = 0.957; PValue = 0.788; mean CPM = 84.41; phosphoinositide-3-kinase, class 2, alpha polypeptide" ID="ID_378440043" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R4: 1.01-fold Down; FDR = 1; PValue = 0.913; mean CPM = 41.33; phosphoinositide-3-kinase, regulatory subunit 4" ID="ID_1050775583" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Innate immunity signaling: FDR = 9.93e-11, PValue = 5.33e-11" ID="ID_1178963025" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TLR2: 8.94-fold Up; FDR = 6.97e-23; PValue = 1.25e-25; mean CPM = 18.41; toll-like receptor 2" ID="ID_51051630" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR3: 10.3-fold Up; FDR = 1.95e-21; PValue = 5.6e-24; mean CPM = 35.70; toll-like receptor 3" ID="ID_816500541" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF7: 14.8-fold Up; FDR = 7.66e-18; PValue = 4.82e-20; mean CPM = 11.54; Macaca mulatta interferon regulatory factor 7 (IRF7), mRNA." ID="ID_1619791540" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C2: 4.8-fold Up; FDR = 3.21e-17; PValue = 2.26e-19; mean CPM = 200.3; Uncharacterized protein" ID="ID_1185691361" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK3: 3.47-fold Up; FDR = 2.3e-12; PValue = 4.07e-14; mean CPM = 12.05; receptor-interacting serine-threonine kinase 3" ID="ID_1918518023" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LY96: 3.13-fold Up; FDR = 1.27e-10; PValue = 3.43e-12; mean CPM = 6.127; lymphocyte antigen 96" ID="ID_1671671810" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR4: 3.45-fold Up; FDR = 3.1e-09; PValue = 1.19e-10; mean CPM = 7.456; Macaca mulatta toll-like receptor 4 (TLR4), mRNA." ID="ID_480128169" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_999430085" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DUSP7: 1.77-fold Down; FDR = 3.08e-08; PValue = 1.52e-09; mean CPM = 22.67; dual specificity phosphatase 7" ID="ID_863789421" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK4: 1.8-fold Up; FDR = 3.31e-08; PValue = 1.64e-09; mean CPM = 12.89; interleukin-1 receptor-associated kinase 4" ID="ID_882455861" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1129702389" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD14: 2.75-fold Down; FDR = 6.54e-07; PValue = 4.46e-08; mean CPM = 5.195; CD14 molecule" ID="ID_691052179" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_691030077" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF1: 1.51-fold Up; FDR = 5.28e-06; PValue = 4.58e-07; mean CPM = 22.13; activating transcription factor 1" ID="ID_1558883308" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K3: 1.45-fold Down; FDR = 7.01e-06; PValue = 6.34e-07; mean CPM = 180.1; mitogen-activated protein kinase kinase 3" ID="ID_866113117" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA5: 3.28-fold Up; FDR = 1.4e-05; PValue = 1.36e-06; mean CPM = 2.288; ribosomal protein S6 kinase, 90kDa, polypeptide 5" ID="ID_1728316606" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1096923460" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R1B: 1.39-fold Down; FDR = 4.37e-05; PValue = 4.86e-06; mean CPM = 233.1; protein phosphatase 2, regulatory subunit A, beta" ID="ID_583724905" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_663894426" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP2: 1.45-fold Up; FDR = 0.000179; PValue = 2.4e-05; mean CPM = 65.31; TGF-beta activated kinase 1/MAP3K7 binding protein 2" ID="ID_1581750140" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2CB: 1.35-fold Up; FDR = 0.000215; PValue = 2.96e-05; mean CPM = 59.68; protein phosphatase 2, catalytic subunit, beta isozyme" ID="ID_1389217973" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP3: 1.5-fold Up; FDR = 0.000276; PValue = 3.92e-05; mean CPM = 11.67; TGF-beta activated kinase 1/MAP3K7 binding protein 3" ID="ID_1910344400" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF2: 1.34-fold Up; FDR = 0.000403; PValue = 6.01e-05; mean CPM = 39.83; activating transcription factor 2" ID="ID_1202854952" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_276397512" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBK1: 1.3-fold Up; FDR = 0.00337; PValue = 0.000674; mean CPM = 30.46; TANK-binding kinase 1" ID="ID_215742471" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R5D: 1.27-fold Down; FDR = 0.00482; PValue = 0.00101; mean CPM = 35.61; protein phosphatase 2, regulatory subunit B', delta" ID="ID_1438581746" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1607199917" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_1659739267" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK3: 1.54-fold Up; FDR = 0.00653; PValue = 0.00144; mean CPM = 19.97; interleukin-1 receptor-associated kinase 3" ID="ID_1769464937" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR5: 1.86-fold Down; FDR = 0.00878; PValue = 0.00203; mean CPM = 3.008; toll-like receptor 5" ID="ID_720224583" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DUSP3: 1.27-fold Down; FDR = 0.0115; PValue = 0.00274; mean CPM = 24.56; dual specificity phosphatase 3" ID="ID_1204604420" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_705649334" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C5: 2.29-fold Up; FDR = 0.0212; PValue = 0.00561; mean CPM = 1.418; complement component 5" ID="ID_926753507" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="UBB: 1.22-fold Up; FDR = 0.0235; PValue = 0.00634; mean CPM = 526.7; ubiquitin B" ID="ID_1328422139" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA1: 1.25-fold Down; FDR = 0.0241; PValue = 0.00652; mean CPM = 21.28; ribosomal protein S6 kinase, 90kDa, polypeptide 1" ID="ID_404283878" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_971778034" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB1: 1.21-fold Up; FDR = 0.0313; PValue = 0.00884; mean CPM = 36.07; cAMP responsive element binding protein 1" ID="ID_542856991" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ECSIT: 1.2-fold Down; FDR = 0.0358; PValue = 0.0104; mean CPM = 54.27; ECSIT homolog (Drosophila)" ID="ID_70472757" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_236766936" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPKAPK3: 1.18-fold Up; FDR = 0.0689; PValue = 0.0225; mean CPM = 35.42; mitogen-activated protein kinase-activated protein kinase 3" ID="ID_1636538719" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C1QB: 2.62-fold Up; FDR = 0.0887; PValue = 0.0304; mean CPM = 1.092; complement component 1, q subcomponent, B chain" ID="ID_1354774784" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_315592932" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_1061256629" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DUSP6: 1.22-fold Up; FDR = 0.131; PValue = 0.0487; mean CPM = 91.01; dual specificity phosphatase 6" ID="ID_1296758342" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_363682709" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EEA1: 1.14-fold Down; FDR = 0.167; PValue = 0.0656; mean CPM = 69.68; early endosome antigen 1" ID="ID_1143975557" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DUSP4: 1.28-fold Down; FDR = 0.199; PValue = 0.0817; mean CPM = 66.70; dual specificity phosphatase 4" ID="ID_270888773" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C1QC: 2.02-fold Up; FDR = 0.203; PValue = 0.0839; mean CPM = 1.322; complement component 1, q subcomponent, C chain" ID="ID_472729246" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MASP1: 1.46-fold Down; FDR = 0.264; PValue = 0.115; mean CPM = 4.467; mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)" ID="ID_489693970" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP1: 1.12-fold Down; FDR = 0.351; PValue = 0.165; mean CPM = 17.96; TGF-beta activated kinase 1/MAP3K7 binding protein 1" ID="ID_497727344" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MEF2C: 1.24-fold Down; FDR = 0.357; PValue = 0.168; mean CPM = 6.816; myocyte enhancer factor 2C" ID="ID_1516207513" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C8B: 2.74-fold Up; FDR = 0.396; PValue = 0.192; mean CPM = 0.8553; complement component 8, beta polypeptide" ID="ID_699725057" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TICAM1: 1.11-fold Down; FDR = 0.398; PValue = 0.192; mean CPM = 26.73; toll-like receptor adaptor molecule 1" ID="ID_1638703513" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_1542855565" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_101398803" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SIGIRR: 1.29-fold Up; FDR = 0.437; PValue = 0.217; mean CPM = 2.330; single immunoglobulin and toll-interleukin 1 receptor (TIR) domain" ID="ID_114144016" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_538606989" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C9: 1.41-fold Up; FDR = 0.505; PValue = 0.262; mean CPM = 1.295; complement component 9" ID="ID_98681869" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MASP2: 1.23-fold Down; FDR = 0.546; PValue = 0.291; mean CPM = 3.073; mannan-binding lectin serine peptidase 2" ID="ID_1344169965" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000000985: 1.2-fold Up; FDR = 0.569; PValue = 0.307; mean CPM = 11.32; Uncharacterized protein" ID="ID_1860730777" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LBP: 1.52-fold Down; FDR = 0.591; PValue = 0.324; mean CPM = 0.8819; lipopolysaccharide binding protein" ID="ID_625093479" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPKAPK2: 1.06-fold Down; FDR = 0.733; PValue = 0.435; mean CPM = 82.16; mitogen-activated protein kinase-activated protein kinase 2" ID="ID_1030739438" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2CA: 1.05-fold Up; FDR = 0.8; PValue = 0.497; mean CPM = 62.78; protein phosphatase 2, catalytic subunit, alpha isozyme" ID="ID_957353134" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR6: 1.07-fold Down; FDR = 0.84; PValue = 0.546; mean CPM = 7.909; toll-like receptor 6" ID="ID_1463888867" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TIRAP: 1.07-fold Up; FDR = 0.841; PValue = 0.548; mean CPM = 8.693; Macaca mulatta toll-interleukin 1 receptor (TIR) domain containing adaptor protein (TIRAP), mRNA." ID="ID_1294700340" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MBL2: 1.3-fold Up; FDR = 0.85; PValue = 0.561; mean CPM = 0.7954; mannose-binding lectin (protein C) 2, soluble (opsonic defect)" ID="ID_1471640070" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C6: 1.72-fold Down; FDR = 0.856; PValue = 0.57; mean CPM = 0.8334; complement component 6" ID="ID_1958733201" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1092344499" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD180: 1.69-fold Down; FDR = 0.868; PValue = 0.585; mean CPM = 0.8488; CD180 molecule" ID="ID_1268145783" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_520576498" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR7: 1.37-fold Down; FDR = 0.878; PValue = 0.597; mean CPM = 0.8402; toll-like receptor 7" ID="ID_821072646" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK1: 1.04-fold Down; FDR = 0.885; PValue = 0.606; mean CPM = 41.54; interleukin-1 receptor-associated kinase 1" ID="ID_1492547983" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK7: 1.04-fold Down; FDR = 0.899; PValue = 0.632; mean CPM = 16.93; Uncharacterized protein" ID="ID_682268122" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LY86: 1.16-fold Down; FDR = 0.903; PValue = 0.649; mean CPM = 0.7948; lymphocyte antigen 86" ID="ID_1619133193" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR10: 1.28-fold Down; FDR = 0.915; PValue = 0.715; mean CPM = 0.8713; toll-like receptor 10" ID="ID_1256000235" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKE: 1.03-fold Up; FDR = 0.929; PValue = 0.737; mean CPM = 21.61; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon" ID="ID_825126141" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZFYVE20: 1.02-fold Down; FDR = 0.937; PValue = 0.75; mean CPM = 48.41; zinc finger, FYVE domain containing 20" ID="ID_25000402" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C8A: 1.06-fold Up; FDR = 0.968; PValue = 0.808; mean CPM = 0.8260; complement component 8, alpha polypeptide" ID="ID_589535985" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_1879477350" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C8G: 1.15-fold Up; FDR = 0.978; PValue = 0.822; mean CPM = 0.8664; complement component 8, gamma polypeptide" ID="ID_826466781" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA3: 1.02-fold Up; FDR = 0.982; PValue = 0.829; mean CPM = 58.16; ribosomal protein S6 kinase, 90kDa, polypeptide 3" ID="ID_550327119" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_661371453" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR9: 1.01-fold Down; FDR = 1; PValue = 0.859; mean CPM = 21.45; Macaca mulatta toll-like receptor 9 (TLR9), mRNA." ID="ID_1868413462" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C7: 1.11-fold Up; FDR = 1; PValue = 0.883; mean CPM = 0.8197; complement component 7" ID="ID_1014349147" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R4: 1.01-fold Down; FDR = 1; PValue = 0.913; mean CPM = 41.33; phosphoinositide-3-kinase, regulatory subunit 4" ID="ID_1390000790" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR1: 1.02-fold Up; FDR = 1; PValue = 0.945; mean CPM = 1.221; toll-like receptor 1" ID="ID_24749342" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_680507744" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-12: FDR = 1.8e-10, PValue = 1e-10" ID="ID_592301062" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TLR2: 8.94-fold Up; FDR = 6.97e-23; PValue = 1.25e-25; mean CPM = 18.41; toll-like receptor 2" ID="ID_779216897" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF1: 18.6-fold Up; FDR = 1.53e-21; PValue = 4.24e-24; mean CPM = 240.7; interferon regulatory factor 1" ID="ID_1810313422" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_1773274335" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1979589648" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR4: 3.45-fold Up; FDR = 3.1e-09; PValue = 1.19e-10; mean CPM = 7.456; Macaca mulatta toll-like receptor 4 (TLR4), mRNA." ID="ID_463466651" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF8: 11.4-fold Up; FDR = 6e-09; PValue = 2.46e-10; mean CPM = 5.558; interferon regulatory factor 8" ID="ID_1225268545" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1937278679" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_51888088" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_873618299" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1224252977" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZNF668: 1.55-fold Down; FDR = 3.17e-06; PValue = 2.59e-07; mean CPM = 25.80; zinc finger protein 668" ID="ID_346699193" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ETV5: 1.43-fold Up; FDR = 5.02e-06; PValue = 4.33e-07; mean CPM = 61.45; ets variant 5" ID="ID_1352985928" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL18R1: 3.18-fold Down; FDR = 5.89e-06; PValue = 5.19e-07; mean CPM = 3.445; interleukin 18 receptor 1" ID="ID_751658766" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_838306575" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT4: 1.79-fold Up; FDR = 2.3e-05; PValue = 2.36e-06; mean CPM = 26.79; signal transducer and activator of transcription 4" ID="ID_390837957" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JMJD6: 1.38-fold Down; FDR = 4.61e-05; PValue = 5.17e-06; mean CPM = 47.49; jumonji domain containing 6" ID="ID_1321605325" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_734138764" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40: 2.76-fold Up; FDR = 0.00039; PValue = 5.79e-05; mean CPM = 9.139; CD40 molecule, TNF receptor superfamily member 5" ID="ID_677602179" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR1: 1.31-fold Up; FDR = 0.00151; PValue = 0.000268; mean CPM = 37.77; interferon gamma receptor 1" ID="ID_346441930" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRRT2: 3.34-fold Down; FDR = 0.00175; PValue = 0.000318; mean CPM = 1.259; proline-rich transmembrane protein 2" ID="ID_1955591821" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="REL: 1.46-fold Down; FDR = 0.00272; PValue = 0.000526; mean CPM = 10.17; v-rel avian reticuloendotheliosis viral oncogene homolog" ID="ID_1223611042" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MST1: 1.59-fold Down; FDR = 0.0041; PValue = 0.000845; mean CPM = 4.582; Uncharacterized protein" ID="ID_573790473" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1805871006" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MST1R: 1.36-fold Up; FDR = 0.00791; PValue = 0.00179; mean CPM = 15.65; macrophage stimulating 1 receptor (c-met-related tyrosine kinase)" ID="ID_1169568692" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12A: 2.09-fold Up; FDR = 0.00924; PValue = 0.00215; mean CPM = 2.872; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)" ID="ID_1946286764" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL18: 1.5-fold Down; FDR = 0.00981; PValue = 0.0023; mean CPM = 6.489; interleukin 18 (interferon-gamma-inducing factor)" ID="ID_1582908472" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYK2: 1.24-fold Down; FDR = 0.0142; PValue = 0.00354; mean CPM = 42.58; tyrosine kinase 2" ID="ID_1835960800" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAB7B: 1.54-fold Down; FDR = 0.0162; PValue = 0.00413; mean CPM = 7.015; Uncharacterized protein" ID="ID_977839753" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1460171646" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1860953506" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_1580670841" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1191310693" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELB: 1.22-fold Down; FDR = 0.0606; PValue = 0.0193; mean CPM = 26.64; v-rel reticuloendotheliosis viral oncogene homolog B" ID="ID_78362219" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT6: 1.18-fold Up; FDR = 0.0727; PValue = 0.024; mean CPM = 217.5; signal transducer and activator of transcription 6, interleukin-4 induced" ID="ID_1710863600" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RXRA: 1.18-fold Down; FDR = 0.077; PValue = 0.0257; mean CPM = 35.60; retinoid X receptor, alpha" ID="ID_1096807814" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K8: 1.35-fold Down; FDR = 0.0831; PValue = 0.0281; mean CPM = 8.912; mitogen-activated protein kinase kinase kinase 8" ID="ID_169790417" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCOA1: 1.18-fold Up; FDR = 0.112; PValue = 0.04; mean CPM = 20.42; nuclear receptor coactivator 1" ID="ID_1353211634" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_70101834" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1266622531" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ALOX15: 2-fold Down; FDR = 0.194; PValue = 0.0791; mean CPM = 0.9607; arachidonate 15-lipoxygenase" ID="ID_1092748683" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAB7A: 1.12-fold Down; FDR = 0.229; PValue = 0.097; mean CPM = 112.6; RAB7A, member RAS oncogene family" ID="ID_1855437903" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12RB2: 1.42-fold Down; FDR = 0.299; PValue = 0.135; mean CPM = 1.728; interleukin 12 receptor, beta 2" ID="ID_1436376165" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EP300: 1.11-fold Up; FDR = 0.312; PValue = 0.142; mean CPM = 162.8; E1A binding protein p300" ID="ID_1354951001" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_536902651" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL23A: 1.39-fold Up; FDR = 0.348; PValue = 0.163; mean CPM = 4.542; interleukin 23, alpha subunit p19" ID="ID_45476597" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_958654563" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_1434270273" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_396857231" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_637130776" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR5: 1.56-fold Down; FDR = 0.487; PValue = 0.249; mean CPM = 1.064; chemokine (C-C motif) receptor 5" ID="ID_1884940136" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_42803301" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF6: 2.34-fold Down; FDR = 0.535; PValue = 0.283; mean CPM = 0.8609; interferon regulatory factor 6" ID="ID_757193381" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD247: 1.43-fold Down; FDR = 0.695; PValue = 0.404; mean CPM = 0.9076; Macaca mulatta CD247 molecule (CD247), mRNA." ID="ID_1805195415" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12RB1: 1.39-fold Up; FDR = 0.703; PValue = 0.41; mean CPM = 0.9665; interleukin 12 receptor, beta 1" ID="ID_1512507535" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1239391451" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_912458683" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_652891373" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3D: 1.22-fold Down; FDR = 0.903; PValue = 0.641; mean CPM = 0.7953; CD3d molecule, delta (CD3-TCR complex)" ID="ID_1934475155" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOS2: 1.4-fold Down; FDR = 0.917; PValue = 0.718; mean CPM = 0.8546; nitric oxide synthase 2, inducible" ID="ID_161298934" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL4: 1.27-fold Down; FDR = 0.933; PValue = 0.745; mean CPM = 0.8077; interleukin 4" ID="ID_1056052682" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPI1: 1.12-fold Down; FDR = 0.935; PValue = 0.747; mean CPM = 1.030; spleen focus forming virus (SFFV) proviral integration oncogene spi1" ID="ID_1658182" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB1: 1.02-fold Down; FDR = 0.936; PValue = 0.749; mean CPM = 62.61; transforming growth factor, beta 1" ID="ID_1878860322" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12B: 1.07-fold Up; FDR = 0.983; PValue = 0.831; mean CPM = 0.8197; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)" ID="ID_95887389" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ALOX12: 1.01-fold Up; FDR = 1; PValue = 0.927; mean CPM = 12.39; arachidonate 12-lipoxygenase" ID="ID_802552468" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPARG: 1.01-fold Down; FDR = 1; PValue = 0.929; mean CPM = 5.609; peroxisome proliferator-activated receptor gamma" ID="ID_776518743" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCR3: 1.03-fold Up; FDR = 1; PValue = 0.943; mean CPM = 0.9843; chemokine (C-X-C motif) receptor 3" ID="ID_1728651487" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_873103136" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL10: 1.21-fold Down; FDR = 1; PValue = 0.964; mean CPM = 0.8614; interleukin 10" ID="ID_146631953" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3G: 1.03-fold Up; FDR = 1; PValue = 0.977; mean CPM = 0.8190; CD3g molecule, gamma (CD3-TCR complex)" ID="ID_856839384" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3E: 1.07-fold Down; FDR = 1; PValue = 0.981; mean CPM = 0.7994; Uncharacterized protein" ID="ID_1530436708" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40LG: 1.01-fold Down; FDR = 1; PValue = 0.982; mean CPM = 0.8653; CD40 ligand" ID="ID_574311383" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL23R: 1.05-fold Down; FDR = 1; PValue = 0.994; mean CPM = 0.7958; interleukin 23 receptor" ID="ID_1572532646" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA1: No Change; FDR = 1; PValue = 0.998; mean CPM = 0.8014; interferon, alpha 1" ID="ID_936391126" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="T cell subtype specific molecules: FDR = 5.46e-10, PValue = 3.14e-10" ID="ID_393802275" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_421255889" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB3: 4.82-fold Down; FDR = 1.82e-12; PValue = 3.09e-14; mean CPM = 9.911; transforming growth factor, beta 3" ID="ID_288430872" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_245960753" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_618645330" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL18R1: 3.18-fold Down; FDR = 5.89e-06; PValue = 5.19e-07; mean CPM = 3.445; interleukin 18 receptor 1" ID="ID_1154560263" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RORA: 1.67-fold Up; FDR = 1.88e-05; PValue = 1.9e-06; mean CPM = 25.24; RAR-related orphan receptor A" ID="ID_1067876148" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT4: 1.79-fold Up; FDR = 2.3e-05; PValue = 2.36e-06; mean CPM = 26.79; signal transducer and activator of transcription 4" ID="ID_1319922270" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1R1: 1.6-fold Up; FDR = 3.35e-05; PValue = 3.61e-06; mean CPM = 123.7; interleukin 1 receptor, type I" ID="ID_409092380" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40: 2.76-fold Up; FDR = 0.00039; PValue = 5.79e-05; mean CPM = 9.139; CD40 molecule, TNF receptor superfamily member 5" ID="ID_27904417" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GATA3: 2.81-fold Up; FDR = 0.000734; PValue = 0.000119; mean CPM = 2.229; GATA binding protein 3" ID="ID_950590613" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR1: 1.31-fold Up; FDR = 0.00151; PValue = 0.000268; mean CPM = 37.77; interferon gamma receptor 1" ID="ID_1656032099" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCR4: 4.65-fold Down; FDR = 0.00226; PValue = 0.000426; mean CPM = 2.073; chemokine (C-X-C motif) receptor 4" ID="ID_993618050" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12A: 2.09-fold Up; FDR = 0.00924; PValue = 0.00215; mean CPM = 2.872; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)" ID="ID_1502213574" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL18: 1.5-fold Down; FDR = 0.00981; PValue = 0.0023; mean CPM = 6.489; interleukin 18 (interferon-gamma-inducing factor)" ID="ID_899715857" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSF2: 2.96-fold Down; FDR = 0.0174; PValue = 0.00447; mean CPM = 73.98; colony stimulating factor 2 (granulocyte-macrophage)" ID="ID_1297780735" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR2: 1.23-fold Up; FDR = 0.0258; PValue = 0.00707; mean CPM = 46.52; interferon gamma receptor 2 (interferon gamma transducer 1)" ID="ID_633677714" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR7: 1.48-fold Down; FDR = 0.0357; PValue = 0.0103; mean CPM = 13.37; chemokine (C-C motif) receptor 7" ID="ID_1875048646" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF11: 1.8-fold Up; FDR = 0.039; PValue = 0.0115; mean CPM = 2.535; tumor necrosis factor (ligand) superfamily, member 11" ID="ID_1254004712" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL3: 2.04-fold Down; FDR = 0.067; PValue = 0.0218; mean CPM = 3.575; chemokine (C-C motif) ligand 3" ID="ID_1216823721" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT6: 1.18-fold Up; FDR = 0.0727; PValue = 0.024; mean CPM = 217.5; signal transducer and activator of transcription 6, interleukin-4 induced" ID="ID_1358150182" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12RB2: 1.42-fold Down; FDR = 0.299; PValue = 0.135; mean CPM = 1.728; interleukin 12 receptor, beta 2" ID="ID_1181791676" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR5: 1.56-fold Down; FDR = 0.487; PValue = 0.249; mean CPM = 1.064; chemokine (C-C motif) receptor 5" ID="ID_1506576684" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF11A: 1.4-fold Down; FDR = 0.676; PValue = 0.388; mean CPM = 0.9723; tumor necrosis factor receptor superfamily, member 11a, NFKB activator" ID="ID_1965304298" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12RB1: 1.39-fold Up; FDR = 0.703; PValue = 0.41; mean CPM = 0.9665; interleukin 12 receptor, beta 1" ID="ID_1283188952" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLX: 1.14-fold Up; FDR = 0.737; PValue = 0.438; mean CPM = 7.730; Uncharacterized protein" ID="ID_381022263" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF4: 1.36-fold Down; FDR = 0.743; PValue = 0.444; mean CPM = 0.8892; tumor necrosis factor receptor superfamily, member 4" ID="ID_634316729" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17RB: 1.24-fold Down; FDR = 0.752; PValue = 0.452; mean CPM = 1.299; interleukin 17 receptor B" ID="ID_846690263" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL4R: 1.05-fold Down; FDR = 0.803; PValue = 0.499; mean CPM = 193.5; interleukin 4 receptor" ID="ID_1828571019" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD4: 1.27-fold Up; FDR = 0.807; PValue = 0.503; mean CPM = 1.122; CD4 molecule" ID="ID_502576028" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR6: 1.51-fold Down; FDR = 0.807; PValue = 0.504; mean CPM = 0.8112; Macaca mulatta chemokine (C-C motif) receptor 6 (CCR6), mRNA." ID="ID_1831559928" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR4: 1.74-fold Up; FDR = 0.831; PValue = 0.533; mean CPM = 0.8536; chemokine (C-C motif) receptor 4" ID="ID_1455001133" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DRB: 1.28-fold Up; FDR = 0.898; PValue = 0.624; mean CPM = 0.8112; MHC class II antigen; Uncharacterized protein" ID="ID_1790783002" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_966695933" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL25: 1.24-fold Down; FDR = 0.899; PValue = 0.631; mean CPM = 0.7976; interleukin 25" ID="ID_1120328595" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB2: 1.05-fold Down; FDR = 0.903; PValue = 0.655; mean CPM = 110.8; transforming growth factor, beta 2" ID="ID_459793589" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR3: 1.43-fold Up; FDR = 0.906; PValue = 0.665; mean CPM = 0.8397; chemokine (C-C motif) receptor 3" ID="ID_748792046" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17A: 1.12-fold Up; FDR = 0.911; PValue = 0.706; mean CPM = 0.7895; interleukin 17A" ID="ID_719941699" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR1: 1.24-fold Up; FDR = 0.915; PValue = 0.714; mean CPM = 0.8590; Macaca mulatta chemokine (C-C motif) receptor 1 (CCR1), mRNA." ID="ID_790938456" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL22: 1.33-fold Down; FDR = 0.928; PValue = 0.735; mean CPM = 0.8193; interleukin 22" ID="ID_1209919362" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICOS: 1.19-fold Up; FDR = 0.931; PValue = 0.741; mean CPM = 0.8158; Uncharacterized protein" ID="ID_1955831984" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL4: 1.27-fold Down; FDR = 0.933; PValue = 0.745; mean CPM = 0.8077; interleukin 4" ID="ID_540734711" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB1: 1.02-fold Down; FDR = 0.936; PValue = 0.749; mean CPM = 62.61; transforming growth factor, beta 1" ID="ID_283728181" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2RA: 1.08-fold Up; FDR = 0.945; PValue = 0.766; mean CPM = 0.8493; interleukin 2 receptor, alpha" ID="ID_1506430919" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17F: 1.11-fold Down; FDR = 0.948; PValue = 0.771; mean CPM = 1.150; interleukin 17F" ID="ID_1946094359" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL21: 1.04-fold Up; FDR = 0.948; PValue = 0.773; mean CPM = 0.8164; interleukin 21" ID="ID_404513635" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL13: 1.05-fold Up; FDR = 0.967; PValue = 0.805; mean CPM = 0.8212; interleukin 13" ID="ID_78311506" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBX21: 1.09-fold Up; FDR = 0.972; PValue = 0.813; mean CPM = 0.9978; T-box 21" ID="ID_708253410" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12B: 1.07-fold Up; FDR = 0.983; PValue = 0.831; mean CPM = 0.8197; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)" ID="ID_1660846861" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL5: 1.05-fold Down; FDR = 1; PValue = 0.862; mean CPM = 1.367; interleukin 5 (colony-stimulating factor, eosinophil)" ID="ID_75639200" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCR3: 1.03-fold Up; FDR = 1; PValue = 0.943; mean CPM = 0.9843; chemokine (C-X-C motif) receptor 3" ID="ID_568233897" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL10: 1.21-fold Down; FDR = 1; PValue = 0.964; mean CPM = 0.8614; interleukin 10" ID="ID_830170338" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40LG: 1.01-fold Down; FDR = 1; PValue = 0.982; mean CPM = 0.8653; CD40 ligand" ID="ID_214971263" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD86: 1.01-fold Down; FDR = 1; PValue = 0.99; mean CPM = 0.8012; CD86 molecule" ID="ID_679217600" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL23R: 1.05-fold Down; FDR = 1; PValue = 0.994; mean CPM = 0.7958; interleukin 23 receptor" ID="ID_671970419" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2: 1.03-fold Up; FDR = 1; PValue = 0.998; mean CPM = 0.7974; interleukin 2" ID="ID_330456917" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="TNF superfamily pathway: FDR = 7.36e-10, PValue = 4.36e-10" ID="ID_261591891" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_1637246843" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF14: 4.66-fold Up; FDR = 2.46e-16; PValue = 2.07e-18; mean CPM = 36.12; Macaca mulatta tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) (TNFRSF14), mRNA." ID="ID_1518932554" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_326155270" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSIP1: 1.94-fold Up; FDR = 3.71e-07; PValue = 2.38e-08; mean CPM = 84.28; PC4 and SFRS1 interacting protein 1" ID="ID_772970726" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_538646915" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_256597220" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1200309402" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1B: 2.24-fold Up; FDR = 2.68e-06; PValue = 2.16e-07; mean CPM = 19.44; tumor necrosis factor receptor superfamily, member 1B" ID="ID_1142969175" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAMLG: 1.43-fold Up; FDR = 1.38e-05; PValue = 1.34e-06; mean CPM = 35.09; calcium modulating ligand" ID="ID_226565831" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF1: 2.6-fold Down; FDR = 1.48e-05; PValue = 1.46e-06; mean CPM = 20.19; TNF receptor-associated factor 1" ID="ID_715981494" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF10D: 1.84-fold Down; FDR = 5.9e-05; PValue = 6.84e-06; mean CPM = 32.06; tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain" ID="ID_1890634780" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_260434303" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40: 2.76-fold Up; FDR = 0.00039; PValue = 5.79e-05; mean CPM = 9.139; CD40 molecule, TNF receptor superfamily member 5" ID="ID_759864552" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF6B: 1.73-fold Down; FDR = 0.000702; PValue = 0.000113; mean CPM = 6.143; tumor necrosis factor receptor superfamily, member 6b, decoy" ID="ID_1505808821" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NR4A1: 1.74-fold Down; FDR = 0.00108; PValue = 0.000184; mean CPM = 312.6; nuclear receptor subfamily 4, group A, member 1" ID="ID_1679141663" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF8: 2.27-fold Down; FDR = 0.00264; PValue = 0.000509; mean CPM = 2.103; tumor necrosis factor receptor superfamily, member 8" ID="ID_1606314214" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELT: 2.44-fold Down; FDR = 0.0028; PValue = 0.000543; mean CPM = 3.224; RELT tumor necrosis factor receptor" ID="ID_119441690" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF12A: 1.24-fold Down; FDR = 0.0133; PValue = 0.00326; mean CPM = 478.0; tumor necrosis factor receptor superfamily, member 12A" ID="ID_211145157" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP10: 1.81-fold Up; FDR = 0.0175; PValue = 0.0045; mean CPM = 2.876; caspase 10, apoptosis-related cysteine peptidase" ID="ID_483379251" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_870876340" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRADD: 1.22-fold Up; FDR = 0.0319; PValue = 0.00907; mean CPM = 34.75; TNFRSF1A-associated via death domain" ID="ID_1099526416" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF4: 1.21-fold Down; FDR = 0.037; PValue = 0.0108; mean CPM = 29.95; TNF receptor-associated factor 4" ID="ID_928820014" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1898584625" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF19: 1.33-fold Up; FDR = 0.0618; PValue = 0.0198; mean CPM = 94.66; tumor necrosis factor receptor superfamily, member 19" ID="ID_1776078828" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FADD: 1.18-fold Down; FDR = 0.0936; PValue = 0.0324; mean CPM = 30.89; Uncharacterized protein" ID="ID_13685776" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF11B: 1.31-fold Down; FDR = 0.121; PValue = 0.0439; mean CPM = 722.1; Uncharacterized protein" ID="ID_1605778868" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LYPLA1: 1.15-fold Up; FDR = 0.193; PValue = 0.0789; mean CPM = 23.69; Uncharacterized protein" ID="ID_400169447" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP6: 1.17-fold Up; FDR = 0.197; PValue = 0.0807; mean CPM = 14.25; caspase 6, apoptosis-related cysteine peptidase" ID="ID_352954679" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP7: 1.15-fold Up; FDR = 0.218; PValue = 0.0916; mean CPM = 21.49; caspase 7, apoptosis-related cysteine peptidase" ID="ID_83535889" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NGFR: 1.72-fold Down; FDR = 0.285; PValue = 0.127; mean CPM = 1.174; nerve growth factor receptor" ID="ID_998796653" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1A: 1.11-fold Up; FDR = 0.297; PValue = 0.134; mean CPM = 134.7; tumor necrosis factor receptor superfamily, member 1A" ID="ID_1109854377" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_1613021283" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF10B: 1.13-fold Down; FDR = 0.343; PValue = 0.16; mean CPM = 40.59; tumor necrosis factor receptor superfamily, member 10b" ID="ID_1319504804" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1658086947" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF18: 1.79-fold Down; FDR = 0.411; PValue = 0.201; mean CPM = 0.9222; tumor necrosis factor receptor superfamily, member 18" ID="ID_120178255" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_586155968" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1765269545" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_602919844" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD27: 1.52-fold Down; FDR = 0.547; PValue = 0.292; mean CPM = 1.004; CD27 molecule" ID="ID_749887474" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NR2C1: 1.09-fold Up; FDR = 0.55; PValue = 0.294; mean CPM = 21.04; nuclear receptor subfamily 2, group C, member 1" ID="ID_990947230" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF3: 1.07-fold Up; FDR = 0.611; PValue = 0.338; mean CPM = 34.56; TNF receptor-associated factor 3" ID="ID_791308607" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF11A: 1.4-fold Down; FDR = 0.676; PValue = 0.388; mean CPM = 0.9723; tumor necrosis factor receptor superfamily, member 11a, NFKB activator" ID="ID_930034130" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LTBR: 1.06-fold Down; FDR = 0.683; PValue = 0.394; mean CPM = 91.13; lymphotoxin beta receptor (TNFR superfamily, member 3)" ID="ID_1433946332" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF10A: 1.06-fold Down; FDR = 0.732; PValue = 0.434; mean CPM = 42.75; tumor necrosis factor receptor superfamily, member 10a" ID="ID_1847411270" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF4: 1.36-fold Down; FDR = 0.743; PValue = 0.444; mean CPM = 0.8892; tumor necrosis factor receptor superfamily, member 4" ID="ID_418891294" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_1357591861" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF25: 1.2-fold Up; FDR = 0.772; PValue = 0.471; mean CPM = 1.687; tumor necrosis factor receptor superfamily, member 25" ID="ID_704794891" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF14: 1.16-fold Down; FDR = 0.903; PValue = 0.645; mean CPM = 0.7940; tumor necrosis factor (ligand) superfamily, member 14" ID="ID_687502155" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP2: 1.05-fold Up; FDR = 0.906; PValue = 0.667; mean CPM = 12.88; caspase 2, apoptosis-related cysteine peptidase" ID="ID_1042993603" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF9: 1.28-fold Down; FDR = 0.911; PValue = 0.7; mean CPM = 0.8318; tumor necrosis factor receptor superfamily, member 9" ID="ID_980333175" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF21: 1.07-fold Down; FDR = 0.922; PValue = 0.726; mean CPM = 6.488; tumor necrosis factor receptor superfamily, member 21" ID="ID_30432712" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF17: 1.08-fold Down; FDR = 0.954; PValue = 0.783; mean CPM = 1.418; tumor necrosis factor receptor superfamily, member 17" ID="ID_1579622819" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF13B: 1.06-fold Up; FDR = 0.954; PValue = 0.784; mean CPM = 0.8104; tumor necrosis factor receptor superfamily, member 13B" ID="ID_1919545261" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP9: 1.01-fold Up; FDR = 1; PValue = 0.908; mean CPM = 19.86; caspase 9, apoptosis-related cysteine peptidase" ID="ID_147160346" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LTB: 1.01-fold Up; FDR = 1; PValue = 0.935; mean CPM = 0.8459; Lymphotoxin-beta (LT-beta)(Tumor necrosis factor C)(TNF-C)(Tumor necrosis factor ligand superfamily member 3)" ID="ID_1640250566" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000006973: 1.09-fold Down; FDR = 1; PValue = 0.938; mean CPM = 0.8165; Uncharacterized protein" ID="ID_1088489463" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LYPLA1: 1.04-fold Up; FDR = 1; PValue = 0.966; mean CPM = 0.8610; lysophospholipase I" ID="ID_937930832" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000007111: 1.12-fold Down; FDR = 1; PValue = 0.993; mean CPM = 0.8245; Uncharacterized protein" ID="ID_601906871" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-23: FDR = 1.26e-08, PValue = 7.69e-09" ID="ID_1270372890" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_1214765722" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1873887863" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5A: 2.28-fold Up; FDR = 6.87e-14; PValue = 8.58e-16; mean CPM = 21.55; signal transducer and activator of transcription 5A" ID="ID_206160823" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_1461669826" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_767905926" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1938720037" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_9384612" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_973769594" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_972600058" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT4: 1.79-fold Up; FDR = 2.3e-05; PValue = 2.36e-06; mean CPM = 26.79; signal transducer and activator of transcription 4" ID="ID_1109234483" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_1705636670" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS3: 1.69-fold Up; FDR = 0.000994; PValue = 0.000167; mean CPM = 37.76; suppressor of cytokine signaling 3" ID="ID_1376532845" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1058780998" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYK2: 1.24-fold Down; FDR = 0.0142; PValue = 0.00354; mean CPM = 42.58; tyrosine kinase 2" ID="ID_560396877" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBID: 1.47-fold Down; FDR = 0.0247; PValue = 0.0067; mean CPM = 6.446; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta" ID="ID_459163224" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_635955209" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARAP3: 1.24-fold Down; FDR = 0.0271; PValue = 0.00747; mean CPM = 26.74; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3" ID="ID_626977590" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIE: 1.3-fold Down; FDR = 0.0272; PValue = 0.00752; mean CPM = 16.93; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon" ID="ID_1299652627" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDPK1: 1.24-fold Down; FDR = 0.0361; PValue = 0.0105; mean CPM = 17.53; 3-phosphoinositide dependent protein kinase-1" ID="ID_1539309904" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1429231339" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIZ: 1.23-fold Up; FDR = 0.0949; PValue = 0.033; mean CPM = 91.08; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta" ID="ID_1547714073" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_753768287" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_933963561" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL23A: 1.39-fold Up; FDR = 0.348; PValue = 0.163; mean CPM = 4.542; interleukin 23, alpha subunit p19" ID="ID_556139258" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1337774189" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17A: 1.12-fold Up; FDR = 0.911; PValue = 0.706; mean CPM = 0.7895; interleukin 17A" ID="ID_1417496486" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17F: 1.11-fold Down; FDR = 0.948; PValue = 0.771; mean CPM = 1.150; interleukin 17F" ID="ID_34519367" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_177283471" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL23R: 1.05-fold Down; FDR = 1; PValue = 0.994; mean CPM = 0.7958; interleukin 23 receptor" ID="ID_1676137512" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="B7.1 / B7.2 (CD80 CD86) CD28: FDR = 4.25e-08, PValue = 2.68e-08" ID="ID_602171511" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="HLA-DMB: 17.5-fold Up; FDR = 2.77e-15; PValue = 2.66e-17; mean CPM = 9.464; HLA class II histocompatibility antigen, DM beta chain Precursor (MHC class II antigen DMB)(Really interesting new gene 7 protein)" ID="ID_156342726" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DPA1: 107-fold Up; FDR = 5.97e-15; PValue = 6.11e-17; mean CPM = 17.08; HLA class II histocompatibility antigen, DP alpha 1 chain Precursor (HLA-SB alpha chain)(MHC class II DP3-alpha)(DP(W3))(DP(W4))" ID="ID_470473938" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DQB1: 31.1-fold Up; FDR = 6.93e-13; PValue = 1.1e-14; mean CPM = 6.675; Macaca mulatta MHC class II antigen (MAMU-DRB), mRNA." ID="ID_434300837" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC4: 1.85-fold Down; FDR = 1.13e-11; PValue = 2.37e-13; mean CPM = 51.58; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4" ID="ID_1628533537" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA1: 15.1-fold Up; FDR = 1.9e-08; PValue = 8.86e-10; mean CPM = 3.665; HLA class II histocompatibility antigen, DQ alpha 1 chain precursor" ID="ID_343734646" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DPB1: 7.73-fold Up; FDR = 4.73e-08; PValue = 2.45e-09; mean CPM = 1.528; Macaca mulatta major histocompatibility complex, class II, DP beta (MAMU-DPB), mRNA." ID="ID_39109408" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_340849962" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_286936178" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_248867703" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1109031848" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL10: 1.55-fold Up; FDR = 5.92e-06; PValue = 5.22e-07; mean CPM = 21.83; B-cell CLL/lymphoma 10" ID="ID_363020562" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1954351257" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_801331310" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPRC: 6.08-fold Up; FDR = 0.000285; PValue = 4.07e-05; mean CPM = 1.220; protein tyrosine phosphatase, receptor type, C" ID="ID_317256213" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC2: 4.03-fold Down; FDR = 0.000346; PValue = 5.06e-05; mean CPM = 1.347; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2" ID="ID_1890644124" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_150326061" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG1: 1.31-fold Down; FDR = 0.00352; PValue = 0.000707; mean CPM = 53.66; phospholipase C, gamma 1" ID="ID_670903137" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1667713893" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FYN: 1.22-fold Up; FDR = 0.0156; PValue = 0.00393; mean CPM = 92.94; FYN oncogene related to SRC, FGR, YES" ID="ID_1317270350" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CARD11: 1.31-fold Down; FDR = 0.0223; PValue = 0.00597; mean CPM = 58.32; caspase recruitment domain family, member 11" ID="ID_1965778246" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBID: 1.47-fold Down; FDR = 0.0247; PValue = 0.0067; mean CPM = 6.446; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta" ID="ID_1399927349" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1980831193" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIE: 1.3-fold Down; FDR = 0.0272; PValue = 0.00752; mean CPM = 16.93; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon" ID="ID_1070258439" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFAT5: 1.21-fold Up; FDR = 0.0273; PValue = 0.00754; mean CPM = 113.0; nuclear factor of activated T-cells 5, tonicity-responsive" ID="ID_967603145" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_521325505" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SIKE1: 1.21-fold Up; FDR = 0.0353; PValue = 0.0102; mean CPM = 31.55; suppressor of IKBKE 1" ID="ID_485901829" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_328056480" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKAP: 1.19-fold Down; FDR = 0.0434; PValue = 0.013; mean CPM = 50.22; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein" ID="ID_1095819202" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DAG1: 1.54-fold Down; FDR = 0.0661; PValue = 0.0214; mean CPM = 3.013; dystroglycan 1 (dystrophin-associated glycoprotein 1)" ID="ID_1913527694" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DOA: 2.74-fold Up; FDR = 0.0694; PValue = 0.0227; mean CPM = 0.9089; HLA class II histocompatibility antigen, DO alpha chain Precursor (MHC class II antigen DOA)(MHC DZ alpha)(MHC DN-alpha)" ID="ID_1300017927" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIZ: 1.23-fold Up; FDR = 0.0949; PValue = 0.033; mean CPM = 91.08; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta" ID="ID_1883052862" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_1160757994" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_211757870" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITPR3: 1.13-fold Up; FDR = 0.194; PValue = 0.079; mean CPM = 157.4; inositol 1,4,5-triphosphate receptor, type 3" ID="ID_1407706068" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_714332216" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAT: 1.44-fold Down; FDR = 0.234; PValue = 0.0996; mean CPM = 1.871; linker for activation of T cells" ID="ID_1679282759" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_212279214" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MALT1: 1.11-fold Down; FDR = 0.35; PValue = 0.164; mean CPM = 42.89; mucosa associated lymphoid tissue lymphoma translocation gene 1" ID="ID_1404222879" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014796: 1.77-fold Up; FDR = 0.381; PValue = 0.182; mean CPM = 0.9085; Uncharacterized protein" ID="ID_49844466" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1125483993" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACTR2: 1.09-fold Up; FDR = 0.44; PValue = 0.219; mean CPM = 263.8; ARP2 actin-related protein 2 homolog (yeast)" ID="ID_603053422" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC1: 1.11-fold Down; FDR = 0.457; PValue = 0.23; mean CPM = 19.06; Uncharacterized protein" ID="ID_621587700" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LCP2: 1.4-fold Up; FDR = 0.496; PValue = 0.256; mean CPM = 1.322; Uncharacterized protein" ID="ID_1835286818" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCQ: 1.56-fold Up; FDR = 0.522; PValue = 0.274; mean CPM = 1.047; Uncharacterized protein" ID="ID_1558282125" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_986007375" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDC42: 1.07-fold Down; FDR = 0.608; PValue = 0.335; mean CPM = 91.67; cell division cycle 42" ID="ID_66717770" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSK: 1.06-fold Down; FDR = 0.673; PValue = 0.386; mean CPM = 45.36; c-src tyrosine kinase" ID="ID_1233374925" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD247: 1.43-fold Down; FDR = 0.695; PValue = 0.404; mean CPM = 0.9076; Macaca mulatta CD247 molecule (CD247), mRNA." ID="ID_217938767" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRAP2: 1.31-fold Up; FDR = 0.701; PValue = 0.408; mean CPM = 3.696; GRB2-related adaptor protein 2" ID="ID_140308232" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC2IP: 1.08-fold Down; FDR = 0.746; PValue = 0.446; mean CPM = 11.08; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein" ID="ID_128061448" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WAS: 1.37-fold Down; FDR = 0.771; PValue = 0.469; mean CPM = 0.9085; Wiskott-Aldrich syndrome" ID="ID_1493474243" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD4: 1.27-fold Up; FDR = 0.807; PValue = 0.503; mean CPM = 1.122; CD4 molecule" ID="ID_1804077144" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTLA4: 1.41-fold Down; FDR = 0.827; PValue = 0.527; mean CPM = 0.8017; cytotoxic T-lymphocyte-associated protein 4" ID="ID_133975936" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1394942874" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV1: 1.25-fold Down; FDR = 0.858; PValue = 0.572; mean CPM = 0.9515; vav 1 guanine nucleotide exchange factor" ID="ID_1509749041" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZAP70: 1.25-fold Down; FDR = 0.872; PValue = 0.59; mean CPM = 0.8996; zeta-chain (TCR) associated protein kinase 70kDa" ID="ID_1901281134" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1359279218" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DRB: 1.28-fold Up; FDR = 0.898; PValue = 0.624; mean CPM = 0.8112; MHC class II antigen; Uncharacterized protein" ID="ID_1388703269" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NR0B2: 1.24-fold Down; FDR = 0.899; PValue = 0.635; mean CPM = 0.7887; nuclear receptor subfamily 0, group B, member 2" ID="ID_1434193731" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3D: 1.22-fold Down; FDR = 0.903; PValue = 0.641; mean CPM = 0.7953; CD3d molecule, delta (CD3-TCR complex)" ID="ID_830705137" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACTR3: 1.13-fold Up; FDR = 0.908; PValue = 0.681; mean CPM = 0.7943; ARP3 actin-related protein 3 homolog (yeast)" ID="ID_1358410925" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA2: 1.13-fold Up; FDR = 0.908; PValue = 0.681; mean CPM = 0.7877; HLA class II histocompatibility antigen, DQ alpha 2 chain Precursor (HLA class II histocompatibility antigen, DQ(6) alpha chain)(DX alpha chain)(HLA-DQA1)" ID="ID_1896199180" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK1: 1.03-fold Down; FDR = 0.911; PValue = 0.705; mean CPM = 18.65; p21 protein (Cdc42/Rac)-activated kinase 1" ID="ID_1511127426" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKE: 1.03-fold Up; FDR = 0.929; PValue = 0.737; mean CPM = 21.61; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon" ID="ID_905090085" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC3: 1.03-fold Down; FDR = 0.952; PValue = 0.78; mean CPM = 13.31; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3" ID="ID_81987333" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_1587590798" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD80: 1.08-fold Up; FDR = 0.971; PValue = 0.812; mean CPM = 1.157; CD80 molecule" ID="ID_958492360" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITK: 1.07-fold Up; FDR = 1; PValue = 0.871; mean CPM = 0.9033; IL2-inducible T-cell kinase" ID="ID_643323567" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_426867674" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3G: 1.03-fold Up; FDR = 1; PValue = 0.977; mean CPM = 0.8190; CD3g molecule, gamma (CD3-TCR complex)" ID="ID_1898049420" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SYK: 1.11-fold Up; FDR = 1; PValue = 0.977; mean CPM = 0.8420; spleen tyrosine kinase" ID="ID_1498359516" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3E: 1.07-fold Down; FDR = 1; PValue = 0.981; mean CPM = 0.7994; Uncharacterized protein" ID="ID_687396123" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD86: 1.01-fold Down; FDR = 1; PValue = 0.99; mean CPM = 0.8012; CD86 molecule" ID="ID_1957823810" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2: 1.03-fold Up; FDR = 1; PValue = 0.998; mean CPM = 0.7974; interleukin 2" ID="ID_817334120" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="GITR: FDR = 9.08e-08, PValue = 5.89e-08" ID="ID_607719342" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CASP5: 68-fold Up; FDR = 3.54e-19; PValue = 1.64e-21; mean CPM = 7.240; caspase 5, apoptosis-related cysteine peptidase" ID="ID_476338134" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_1810204426" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP4: 4.99-fold Up; FDR = 6.91e-12; PValue = 1.4e-13; mean CPM = 56.06; Caspase" ID="ID_1263658032" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_439412169" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_1638813206" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF1: 2.6-fold Down; FDR = 1.48e-05; PValue = 1.46e-06; mean CPM = 20.19; TNF receptor-associated factor 1" ID="ID_1556768764" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF18: 3.1-fold Down; FDR = 2.37e-05; PValue = 2.45e-06; mean CPM = 13.02; tumor necrosis factor (ligand) superfamily, member 18" ID="ID_451483342" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_1292236972" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="REL: 1.46-fold Down; FDR = 0.00272; PValue = 0.000526; mean CPM = 10.17; v-rel avian reticuloendotheliosis viral oncogene homolog" ID="ID_1950603386" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_671171765" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K14: 1.47-fold Down; FDR = 0.00704; PValue = 0.00157; mean CPM = 9.470; mitogen-activated protein kinase kinase kinase 14" ID="ID_1890363788" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP10: 1.81-fold Up; FDR = 0.0175; PValue = 0.0045; mean CPM = 2.876; caspase 10, apoptosis-related cysteine peptidase" ID="ID_1736022457" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1641653270" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELB: 1.22-fold Down; FDR = 0.0606; PValue = 0.0193; mean CPM = 26.64; v-rel reticuloendotheliosis viral oncogene homolog B" ID="ID_854035187" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SIVA1: 1.16-fold Up; FDR = 0.105; PValue = 0.0372; mean CPM = 52.78; SIVA1, apoptosis-inducing factor" ID="ID_66203067" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_1101267217" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP6: 1.17-fold Up; FDR = 0.197; PValue = 0.0807; mean CPM = 14.25; caspase 6, apoptosis-related cysteine peptidase" ID="ID_1137918440" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP7: 1.15-fold Up; FDR = 0.218; PValue = 0.0916; mean CPM = 21.49; caspase 7, apoptosis-related cysteine peptidase" ID="ID_1917334081" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF18: 1.79-fold Down; FDR = 0.411; PValue = 0.201; mean CPM = 0.9222; tumor necrosis factor receptor superfamily, member 18" ID="ID_862831960" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF3: 1.07-fold Up; FDR = 0.611; PValue = 0.338; mean CPM = 34.56; TNF receptor-associated factor 3" ID="ID_33088714" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_253769921" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_693215233" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP2: 1.05-fold Up; FDR = 0.906; PValue = 0.667; mean CPM = 12.88; caspase 2, apoptosis-related cysteine peptidase" ID="ID_1265650535" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKE: 1.03-fold Up; FDR = 0.929; PValue = 0.737; mean CPM = 21.61; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon" ID="ID_1170738126" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP9: 1.01-fold Up; FDR = 1; PValue = 0.908; mean CPM = 19.86; caspase 9, apoptosis-related cysteine peptidase" ID="ID_322127650" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="ICOS: FDR = 1.7e-07, PValue = 1.13e-07" ID="ID_566103445" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="HLA-DMB: 17.5-fold Up; FDR = 2.77e-15; PValue = 2.66e-17; mean CPM = 9.464; HLA class II histocompatibility antigen, DM beta chain Precursor (MHC class II antigen DMB)(Really interesting new gene 7 protein)" ID="ID_502059881" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DPA1: 107-fold Up; FDR = 5.97e-15; PValue = 6.11e-17; mean CPM = 17.08; HLA class II histocompatibility antigen, DP alpha 1 chain Precursor (HLA-SB alpha chain)(MHC class II DP3-alpha)(DP(W3))(DP(W4))" ID="ID_1255080217" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DQB1: 31.1-fold Up; FDR = 6.93e-13; PValue = 1.1e-14; mean CPM = 6.675; Macaca mulatta MHC class II antigen (MAMU-DRB), mRNA." ID="ID_1554883070" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA1: 15.1-fold Up; FDR = 1.9e-08; PValue = 8.86e-10; mean CPM = 3.665; HLA class II histocompatibility antigen, DQ alpha 1 chain precursor" ID="ID_1644497059" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DPB1: 7.73-fold Up; FDR = 4.73e-08; PValue = 2.45e-09; mean CPM = 1.528; Macaca mulatta major histocompatibility complex, class II, DP beta (MAMU-DPB), mRNA." ID="ID_760520398" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_715946269" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_1208699608" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_366111278" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC2: 4.03-fold Down; FDR = 0.000346; PValue = 5.06e-05; mean CPM = 1.347; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2" ID="ID_816076486" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAD: 1.36-fold Down; FDR = 0.000605; PValue = 9.52e-05; mean CPM = 48.46; BCL2-associated agonist of cell death" ID="ID_741242411" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GAB2: 1.33-fold Down; FDR = 0.00208; PValue = 0.000387; mean CPM = 22.59; GRB2-associated binding protein 2" ID="ID_589439769" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG1: 1.31-fold Down; FDR = 0.00352; PValue = 0.000707; mean CPM = 53.66; phospholipase C, gamma 1" ID="ID_333133031" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_270743295" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GLRX3: 1.23-fold Up; FDR = 0.0155; PValue = 0.00392; mean CPM = 59.65; glutaredoxin 3" ID="ID_1323016424" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBID: 1.47-fold Down; FDR = 0.0247; PValue = 0.0067; mean CPM = 6.446; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta" ID="ID_679580010" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1298934208" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARAP3: 1.24-fold Down; FDR = 0.0271; PValue = 0.00747; mean CPM = 26.74; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3" ID="ID_813936720" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIE: 1.3-fold Down; FDR = 0.0272; PValue = 0.00752; mean CPM = 16.93; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon" ID="ID_1796231754" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDPK1: 1.24-fold Down; FDR = 0.0361; PValue = 0.0105; mean CPM = 17.53; 3-phosphoinositide dependent protein kinase-1" ID="ID_224210532" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_782775790" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKAP: 1.19-fold Down; FDR = 0.0434; PValue = 0.013; mean CPM = 50.22; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein" ID="ID_409348419" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DAG1: 1.54-fold Down; FDR = 0.0661; PValue = 0.0214; mean CPM = 3.013; dystroglycan 1 (dystrophin-associated glycoprotein 1)" ID="ID_1287954116" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DOA: 2.74-fold Up; FDR = 0.0694; PValue = 0.0227; mean CPM = 0.9089; HLA class II histocompatibility antigen, DO alpha chain Precursor (MHC class II antigen DOA)(MHC DZ alpha)(MHC DN-alpha)" ID="ID_897555489" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIZ: 1.23-fold Up; FDR = 0.0949; PValue = 0.033; mean CPM = 91.08; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta" ID="ID_1312363275" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_1321700535" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITPR3: 1.13-fold Up; FDR = 0.194; PValue = 0.079; mean CPM = 157.4; inositol 1,4,5-triphosphate receptor, type 3" ID="ID_664654618" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_410145649" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAT: 1.44-fold Down; FDR = 0.234; PValue = 0.0996; mean CPM = 1.871; linker for activation of T cells" ID="ID_1907800216" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_1659835160" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_1719874590" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014796: 1.77-fold Up; FDR = 0.381; PValue = 0.182; mean CPM = 0.9085; Uncharacterized protein" ID="ID_632241699" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1776543020" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LCP2: 1.4-fold Up; FDR = 0.496; PValue = 0.256; mean CPM = 1.322; Uncharacterized protein" ID="ID_1992788384" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_1364424831" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDC42: 1.07-fold Down; FDR = 0.608; PValue = 0.335; mean CPM = 91.67; cell division cycle 42" ID="ID_1056344619" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD247: 1.43-fold Down; FDR = 0.695; PValue = 0.404; mean CPM = 0.9076; Macaca mulatta CD247 molecule (CD247), mRNA." ID="ID_158804221" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV1: 1.25-fold Down; FDR = 0.858; PValue = 0.572; mean CPM = 0.9515; vav 1 guanine nucleotide exchange factor" ID="ID_1181938986" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZAP70: 1.25-fold Down; FDR = 0.872; PValue = 0.59; mean CPM = 0.8996; zeta-chain (TCR) associated protein kinase 70kDa" ID="ID_120241280" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DRB: 1.28-fold Up; FDR = 0.898; PValue = 0.624; mean CPM = 0.8112; MHC class II antigen; Uncharacterized protein" ID="ID_804685570" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3D: 1.22-fold Down; FDR = 0.903; PValue = 0.641; mean CPM = 0.7953; CD3d molecule, delta (CD3-TCR complex)" ID="ID_1916364810" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA2: 1.13-fold Up; FDR = 0.908; PValue = 0.681; mean CPM = 0.7877; HLA class II histocompatibility antigen, DQ alpha 2 chain Precursor (HLA class II histocompatibility antigen, DQ(6) alpha chain)(DX alpha chain)(HLA-DQA1)" ID="ID_1519027886" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICOSLG: 1.07-fold Down; FDR = 0.909; PValue = 0.684; mean CPM = 6.739; inducible T-cell co-stimulator ligand" ID="ID_96155108" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAT1: 1.13-fold Down; FDR = 0.911; PValue = 0.702; mean CPM = 0.7899; T cell receptor associated transmembrane adaptor 1" ID="ID_1070837691" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKE: 1.03-fold Up; FDR = 0.929; PValue = 0.737; mean CPM = 21.61; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon" ID="ID_841948251" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICOS: 1.19-fold Up; FDR = 0.931; PValue = 0.741; mean CPM = 0.8158; Uncharacterized protein" ID="ID_1427053911" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMEM55B: 1.02-fold Up; FDR = 0.963; PValue = 0.798; mean CPM = 15.78; transmembrane protein 55B" ID="ID_916655012" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_340015712" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD80: 1.08-fold Up; FDR = 0.971; PValue = 0.812; mean CPM = 1.157; CD80 molecule" ID="ID_1075941443" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITK: 1.07-fold Up; FDR = 1; PValue = 0.871; mean CPM = 0.9033; IL2-inducible T-cell kinase" ID="ID_658072835" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_1201778581" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3G: 1.03-fold Up; FDR = 1; PValue = 0.977; mean CPM = 0.8190; CD3g molecule, gamma (CD3-TCR complex)" ID="ID_340703607" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3E: 1.07-fold Down; FDR = 1; PValue = 0.981; mean CPM = 0.7994; Uncharacterized protein" ID="ID_1301518806" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD86: 1.01-fold Down; FDR = 1; PValue = 0.99; mean CPM = 0.8012; CD86 molecule" ID="ID_342646042" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Eotaxin / CCL11: FDR = 1.7e-06, PValue = 1.16e-06" ID="ID_1452722648" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="GNG10: 2.27-fold Up; FDR = 1.24e-13; PValue = 1.66e-15; mean CPM = 24.29; guanine nucleotide binding protein (G protein), gamma 10" ID="ID_1748624009" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL13: 12.3-fold Up; FDR = 4.33e-10; PValue = 1.35e-11; mean CPM = 3.824; chemokine (C-C motif) ligand 13" ID="ID_542498491" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL7: 8.24-fold Up; FDR = 6.67e-09; PValue = 2.75e-10; mean CPM = 8.249; chemokine (C-C motif) ligand 7" ID="ID_1207583412" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CFL2: 1.88-fold Down; FDR = 1.06e-08; PValue = 4.59e-10; mean CPM = 58.30; cofilin 2 (muscle)" ID="ID_1783966329" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL5: 6.74-fold Up; FDR = 2.65e-07; PValue = 1.64e-08; mean CPM = 30.35; chemokine (C-C motif) ligand 5" ID="ID_830566079" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG11: 1.65-fold Up; FDR = 2.71e-07; PValue = 1.68e-08; mean CPM = 86.60; guanine nucleotide binding protein (G protein), gamma 11" ID="ID_1724947352" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYLK: 2.29-fold Down; FDR = 1.02e-06; PValue = 7.45e-08; mean CPM = 128.3; myosin light chain kinase" ID="ID_354377923" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCB1: 1.71-fold Up; FDR = 1.31e-06; PValue = 9.73e-08; mean CPM = 34.36; phospholipase C, beta 1 (phosphoinositide-specific)" ID="ID_35691437" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_524003040" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_558716641" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1073316088" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL11: 6.86-fold Up; FDR = 2.69e-05; PValue = 2.82e-06; mean CPM = 4.204; chemokine (C-C motif) ligand 11" ID="ID_223615466" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAI1: 1.47-fold Up; FDR = 5.94e-05; PValue = 6.9e-06; mean CPM = 97.19; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1" ID="ID_1179819716" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACA: 1.36-fold Down; FDR = 0.000167; PValue = 2.22e-05; mean CPM = 37.75; protein kinase, cAMP-dependent, catalytic, alpha" ID="ID_282579528" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_51759468" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PREX1: 1.34-fold Down; FDR = 0.000592; PValue = 9.28e-05; mean CPM = 89.02; phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1" ID="ID_1792937769" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYBA: 1.34-fold Up; FDR = 0.00107; PValue = 0.000183; mean CPM = 376.6; cytochrome b-245, alpha polypeptide" ID="ID_1587040591" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAS1: 1.31-fold Down; FDR = 0.00158; PValue = 0.000283; mean CPM = 564.9; Uncharacterized protein" ID="ID_530783723" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PFN2: 1.41-fold Up; FDR = 0.00199; PValue = 0.000369; mean CPM = 25.56; Profilin" ID="ID_563337390" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHOA: 1.28-fold Down; FDR = 0.00295; PValue = 0.000575; mean CPM = 277.8; ras homolog gene family, member A" ID="ID_946667246" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP1R12B: 1.52-fold Down; FDR = 0.00383; PValue = 0.000782; mean CPM = 15.41; protein phosphatase 1, regulatory (inhibitor) subunit 12B" ID="ID_1988568333" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG12: 1.31-fold Up; FDR = 0.00387; PValue = 0.000792; mean CPM = 24.97; guanine nucleotide binding protein (G protein), gamma 12" ID="ID_1984423751" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYL12B: 1.28-fold Up; FDR = 0.00408; PValue = 0.00084; mean CPM = 372.0; myosin, light chain 12B, regulatory" ID="ID_1749103866" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LIMK2: 1.51-fold Down; FDR = 0.00509; PValue = 0.00108; mean CPM = 60.03; LIM domain kinase 2" ID="ID_190366958" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL8: 3.3-fold Up; FDR = 0.00609; PValue = 0.00133; mean CPM = 1.313; chemokine (C-C motif) ligand 8" ID="ID_268810559" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYB5R3: 1.25-fold Down; FDR = 0.00983; PValue = 0.0023; mean CPM = 422.4; cytochrome b5 reductase 3" ID="ID_32007591" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARF6: 1.24-fold Down; FDR = 0.0106; PValue = 0.00251; mean CPM = 87.11; ADP-ribosylation factor 6" ID="ID_1361349838" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCZ: 1.51-fold Up; FDR = 0.0152; PValue = 0.00381; mean CPM = 10.46; protein kinase C, zeta" ID="ID_844743834" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1385293240" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DOCK2: 1.4-fold Up; FDR = 0.0216; PValue = 0.00573; mean CPM = 37.89; dedicator of cytokinesis 2" ID="ID_1957476835" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1493019267" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INPP5D: 1.88-fold Down; FDR = 0.0276; PValue = 0.00763; mean CPM = 5.690; inositol polyphosphate-5-phosphatase, 145kDa" ID="ID_1132778382" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC2: 2.96-fold Up; FDR = 0.0309; PValue = 0.00872; mean CPM = 0.9737; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)" ID="ID_1309980343" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDPK1: 1.24-fold Down; FDR = 0.0361; PValue = 0.0105; mean CPM = 17.53; 3-phosphoinositide dependent protein kinase-1" ID="ID_190734539" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCB2: 3.68-fold Down; FDR = 0.0481; PValue = 0.0147; mean CPM = 1.557; Uncharacterized protein" ID="ID_1257442512" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DAG1: 1.54-fold Down; FDR = 0.0661; PValue = 0.0214; mean CPM = 3.013; dystroglycan 1 (dystrophin-associated glycoprotein 1)" ID="ID_1021713749" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_1377567491" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYTH4: 2.72-fold Down; FDR = 0.0737; PValue = 0.0244; mean CPM = 0.8845; cytohesin 4" ID="ID_104227043" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TIAM1: 1.23-fold Up; FDR = 0.0747; PValue = 0.0248; mean CPM = 38.38; T-cell lymphoma invasion and metastasis 1" ID="ID_434260710" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG2: 1.64-fold Up; FDR = 0.117; PValue = 0.0421; mean CPM = 2.320; guanine nucleotide binding protein (G protein), gamma 2" ID="ID_5255994" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG3: 1.6-fold Down; FDR = 0.155; PValue = 0.0601; mean CPM = 1.706; guanine nucleotide binding protein (G protein), gamma 3" ID="ID_1634567206" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLD1: 1.24-fold Down; FDR = 0.162; PValue = 0.0634; mean CPM = 15.80; phospholipase D1, phosphatidylcholine-specific" ID="ID_1786970864" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTEN: 1.14-fold Up; FDR = 0.166; PValue = 0.065; mean CPM = 89.60; phosphatase and tensin homolog" ID="ID_1501341609" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ROCK2: 1.14-fold Up; FDR = 0.166; PValue = 0.065; mean CPM = 247.7; Rho-associated, coiled-coil containing protein kinase 2" ID="ID_385901491" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP1R12A: 1.14-fold Up; FDR = 0.167; PValue = 0.0655; mean CPM = 282.7; protein phosphatase 1, regulatory (inhibitor) subunit 12A" ID="ID_658590352" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITPR3: 1.13-fold Up; FDR = 0.194; PValue = 0.079; mean CPM = 157.4; inositol 1,4,5-triphosphate receptor, type 3" ID="ID_277481377" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_890507739" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_1896923074" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PFN1: 1.12-fold Down; FDR = 0.337; PValue = 0.156; mean CPM = 965.8; profilin 1" ID="ID_1278743559" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG7: 1.75-fold Down; FDR = 0.366; PValue = 0.174; mean CPM = 0.9647; guanine nucleotide binding protein (G protein), gamma 7" ID="ID_1273286379" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1413175082" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2: 1.1-fold Up; FDR = 0.394; PValue = 0.191; mean CPM = 102.5; PTK2 protein tyrosine kinase 2" ID="ID_1459603396" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_729234687" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL26: 1.74-fold Down; FDR = 0.423; PValue = 0.208; mean CPM = 0.8756; chemokine (C-C motif) ligand 26" ID="ID_865286116" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACTR2: 1.09-fold Up; FDR = 0.44; PValue = 0.219; mean CPM = 263.8; ARP2 actin-related protein 2 homolog (yeast)" ID="ID_1273050026" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1386591560" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGR: 1.63-fold Up; FDR = 0.516; PValue = 0.269; mean CPM = 1.191; Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog" ID="ID_1116761318" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG4: 1.65-fold Down; FDR = 0.524; PValue = 0.275; mean CPM = 0.8771; guanine nucleotide binding protein (G protein), gamma 4" ID="ID_462944539" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCF2: 1.29-fold Up; FDR = 0.525; PValue = 0.276; mean CPM = 2.178; Uncharacterized protein" ID="ID_815709186" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_901340864" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNB1: 1.08-fold Down; FDR = 0.565; PValue = 0.305; mean CPM = 299.4; guanine nucleotide binding protein (G protein), beta polypeptide 1" ID="ID_1595869681" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP1CB: 1.08-fold Up; FDR = 0.566; PValue = 0.306; mean CPM = 108.6; protein phosphatase 1, catalytic subunit, beta isozyme" ID="ID_339136295" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYBB: 1.52-fold Up; FDR = 0.705; PValue = 0.412; mean CPM = 0.9872; cytochrome b-245, beta polypeptide" ID="ID_1292426532" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCB: 1.86-fold Up; FDR = 0.727; PValue = 0.43; mean CPM = 0.8705; protein kinase C, beta" ID="ID_1654303188" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG13: 1.67-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8104; guanine nucleotide binding protein (G protein), gamma 13" ID="ID_724865678" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WAS: 1.37-fold Down; FDR = 0.771; PValue = 0.469; mean CPM = 0.9085; Wiskott-Aldrich syndrome" ID="ID_1933491472" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACG: 1.51-fold Down; FDR = 0.795; PValue = 0.491; mean CPM = 0.8026; protein kinase, cAMP-dependent, catalytic, gamma" ID="ID_1306123669" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HCK: 1.3-fold Down; FDR = 0.797; PValue = 0.494; mean CPM = 0.9272; Uncharacterized protein" ID="ID_999928916" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV1: 1.25-fold Down; FDR = 0.858; PValue = 0.572; mean CPM = 0.9515; vav 1 guanine nucleotide exchange factor" ID="ID_1701129642" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_171151849" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAQ: 1.05-fold Down; FDR = 0.889; PValue = 0.611; mean CPM = 9.623; Guanine nucleotide-binding protein G(Q) subunit alpha; Uncharacterized protein" ID="ID_820782545" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BMX: 1.42-fold Down; FDR = 0.898; PValue = 0.625; mean CPM = 0.8398; BMX non-receptor tyrosine kinase" ID="ID_1030348596" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PFN3: 1.24-fold Down; FDR = 0.899; PValue = 0.631; mean CPM = 0.8001; profilin 3" ID="ID_696532215" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PFN3: 1.14-fold Down; FDR = 0.903; PValue = 0.658; mean CPM = 0.7895; Uncharacterized protein" ID="ID_1706581274" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR3: 1.43-fold Up; FDR = 0.906; PValue = 0.665; mean CPM = 0.8397; chemokine (C-C motif) receptor 3" ID="ID_1365476701" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACTR3: 1.13-fold Up; FDR = 0.908; PValue = 0.681; mean CPM = 0.7943; ARP3 actin-related protein 3 homolog (yeast)" ID="ID_1124818203" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYL2: 1.15-fold Up; FDR = 0.909; PValue = 0.69; mean CPM = 0.7911; myosin, light chain 2, regulatory, cardiac, slow" ID="ID_90364463" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACB: 1.03-fold Up; FDR = 0.911; PValue = 0.694; mean CPM = 30.10; protein kinase, cAMP-dependent, catalytic, beta" ID="ID_1439641543" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LIMK2: 1.14-fold Down; FDR = 0.911; PValue = 0.697; mean CPM = 0.7896; LIM domain kinase 2" ID="ID_1994421221" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK1: 1.03-fold Down; FDR = 0.911; PValue = 0.705; mean CPM = 18.65; p21 protein (Cdc42/Rac)-activated kinase 1" ID="ID_454248055" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KAT5: 1.03-fold Down; FDR = 0.916; PValue = 0.715; mean CPM = 42.22; K(lysine) acetyltransferase 5" ID="ID_1730186933" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_670174251" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG5: 1.02-fold Down; FDR = 0.952; PValue = 0.781; mean CPM = 21.93; guanine nucleotide binding protein (G protein), gamma 5" ID="ID_596118004" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMEM55B: 1.02-fold Up; FDR = 0.963; PValue = 0.798; mean CPM = 15.78; transmembrane protein 55B" ID="ID_33529003" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_1986537757" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYH6: 1.11-fold Up; FDR = 0.975; PValue = 0.817; mean CPM = 1.001; myosin, heavy chain 6, cardiac muscle, alpha" ID="ID_1842383694" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG8: 1.11-fold Down; FDR = 0.989; PValue = 0.84; mean CPM = 0.8494; guanine nucleotide binding protein (G protein), gamma 8" ID="ID_965938788" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_737754639" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNGT1: 1.05-fold Up; FDR = 1; PValue = 0.871; mean CPM = 0.8362; guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1" ID="ID_424979381" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOX1: 1.11-fold Up; FDR = 1; PValue = 0.922; mean CPM = 0.8469; NADPH oxidase 1" ID="ID_713749458" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BTK: No Change; FDR = 1; PValue = 0.965; mean CPM = 0.8336; Bruton agammaglobulinemia tyrosine kinase" ID="ID_1433147656" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAQ: No Change; FDR = 1; PValue = 0.975; mean CPM = 15.20; guanine nucleotide binding protein (G protein), q polypeptide" ID="ID_100130967" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV2: No Change; FDR = 1; PValue = 0.976; mean CPM = 25.65; vav 2 guanine nucleotide exchange factor" ID="ID_1591931728" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SFTPD: 1.03-fold Down; FDR = 1; PValue = 0.982; mean CPM = 0.8042; surfactant protein D" ID="ID_314340471" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL24: 1.01-fold Up; FDR = 1; PValue = 0.999; mean CPM = 0.8072; Uncharacterized protein" ID="ID_110092814" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="SDF1 / CXCR4: FDR = 2.84e-06, PValue = 2e-06" ID="ID_712560664" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_378234094" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2B: 3.54-fold Up; FDR = 1.24e-07; PValue = 7.07e-09; mean CPM = 5.971; PTK2B protein tyrosine kinase 2 beta" ID="ID_1870569124" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1172540325" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1156207137" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAI1: 1.47-fold Up; FDR = 5.94e-05; PValue = 6.9e-06; mean CPM = 97.19; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1" ID="ID_1698580937" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCAR1: 1.36-fold Up; FDR = 0.000193; PValue = 2.61e-05; mean CPM = 210.4; breast cancer anti-estrogen resistance 1" ID="ID_426054830" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCR4: 4.65-fold Down; FDR = 0.00226; PValue = 0.000426; mean CPM = 2.073; chemokine (C-X-C motif) receptor 4" ID="ID_1088086717" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG1: 1.31-fold Down; FDR = 0.00352; PValue = 0.000707; mean CPM = 53.66; phospholipase C, gamma 1" ID="ID_308463619" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_506102826" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_113925206" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_216123756" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2: 1.1-fold Up; FDR = 0.394; PValue = 0.191; mean CPM = 102.5; PTK2 protein tyrosine kinase 2" ID="ID_1499058913" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1536976778" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL12: 1.27-fold Down; FDR = 0.488; PValue = 0.251; mean CPM = 4.383; chemokine (C-X-C motif) ligand 12" ID="ID_1048537711" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNB1: 1.08-fold Down; FDR = 0.565; PValue = 0.305; mean CPM = 299.4; guanine nucleotide binding protein (G protein), beta polypeptide 1" ID="ID_339998430" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCB: 1.86-fold Up; FDR = 0.727; PValue = 0.43; mean CPM = 0.8705; protein kinase C, beta" ID="ID_1072891685" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRK: 1.05-fold Up; FDR = 0.791; PValue = 0.488; mean CPM = 59.92; v-crk sarcoma virus CT10 oncogene homolog (avian)" ID="ID_958353014" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAQ: 1.05-fold Down; FDR = 0.889; PValue = 0.611; mean CPM = 9.623; Guanine nucleotide-binding protein G(Q) subunit alpha; Uncharacterized protein" ID="ID_1379769340" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_321307725" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNGT1: 1.05-fold Up; FDR = 1; PValue = 0.871; mean CPM = 0.8362; guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1" ID="ID_513823820" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAQ: No Change; FDR = 1; PValue = 0.975; mean CPM = 15.20; guanine nucleotide binding protein (G protein), q polypeptide" ID="ID_981128235" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-18: FDR = 3.54e-06, PValue = 2.56e-06" ID="ID_49403340" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="IL18BP: 21.2-fold Up; FDR = 4.51e-22; PValue = 1.06e-24; mean CPM = 73.89; Macaca mulatta interleukin 18 binding protein (IL18BP), mRNA." ID="ID_1013517943" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_152070817" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL18R1: 3.18-fold Down; FDR = 5.89e-06; PValue = 5.19e-07; mean CPM = 3.445; interleukin 18 receptor 1" ID="ID_848079140" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1R1: 1.6-fold Up; FDR = 3.35e-05; PValue = 3.61e-06; mean CPM = 123.7; interleukin 1 receptor, type I" ID="ID_1537736509" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_654886455" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_458679876" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K14: 1.47-fold Down; FDR = 0.00704; PValue = 0.00157; mean CPM = 9.470; mitogen-activated protein kinase kinase kinase 14" ID="ID_622077730" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GADD45B: 1.49-fold Down; FDR = 0.0082; PValue = 0.00187; mean CPM = 175.6; growth arrest and DNA-damage-inducible, beta" ID="ID_855814335" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12A: 2.09-fold Up; FDR = 0.00924; PValue = 0.00215; mean CPM = 2.872; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)" ID="ID_1513689208" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL18: 1.5-fold Down; FDR = 0.00981; PValue = 0.0023; mean CPM = 6.489; interleukin 18 (interferon-gamma-inducing factor)" ID="ID_285747357" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GADD45G: 1.49-fold Up; FDR = 0.0173; PValue = 0.00444; mean CPM = 12.01; growth arrest and DNA-damage-inducible, gamma" ID="ID_1530254527" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBID: 1.47-fold Down; FDR = 0.0247; PValue = 0.0067; mean CPM = 6.446; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta" ID="ID_1148957044" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIE: 1.3-fold Down; FDR = 0.0272; PValue = 0.00752; mean CPM = 16.93; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon" ID="ID_1398576198" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL18RAP: 2.95-fold Down; FDR = 0.0275; PValue = 0.00761; mean CPM = 1.220; interleukin 18 receptor accessory protein" ID="ID_747462619" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_1922574065" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GADD45A: 1.22-fold Up; FDR = 0.0344; PValue = 0.00989; mean CPM = 127.8; growth arrest and DNA-damage-inducible, alpha" ID="ID_190748518" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1682124956" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1RAP: 1.35-fold Up; FDR = 0.0392; PValue = 0.0116; mean CPM = 10.66; interleukin 1 receptor accessory protein" ID="ID_1662114129" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LEP: 1.67-fold Down; FDR = 0.0401; PValue = 0.0118; mean CPM = 63.70; leptin" ID="ID_1694073706" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIZ: 1.23-fold Up; FDR = 0.0949; PValue = 0.033; mean CPM = 91.08; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta" ID="ID_1527711851" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_869163464" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1834004893" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_265271322" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1627505623" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK1: 1.04-fold Down; FDR = 0.885; PValue = 0.606; mean CPM = 41.54; interleukin-1 receptor-associated kinase 1" ID="ID_1836558641" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_1818457849" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12B: 1.07-fold Up; FDR = 0.983; PValue = 0.831; mean CPM = 0.8197; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)" ID="ID_1313444010" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_865343193" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_1955460004" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2: 1.03-fold Up; FDR = 1; PValue = 0.998; mean CPM = 0.7974; interleukin 2" ID="ID_1416390177" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="p53: FDR = 4.96e-06, PValue = 3.67e-06" ID="ID_1782383138" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_402652277" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RRM2B: 2.34-fold Up; FDR = 5.88e-13; PValue = 9.04e-15; mean CPM = 96.48; ribonucleotide reductase M2 B (TP53 inducible)" ID="ID_1213846220" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PMAIP1: 8.66-fold Up; FDR = 1.12e-12; PValue = 1.84e-14; mean CPM = 31.02; Phorbol-12-myristate-13-acetate-induced protein 1; Uncharacterized protein" ID="ID_1823951837" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND3: 2.27-fold Down; FDR = 8.38e-11; PValue = 2.15e-12; mean CPM = 86.90; cyclin D3" ID="ID_1275145899" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BID: 1.66-fold Up; FDR = 5.41e-09; PValue = 2.19e-10; mean CPM = 35.19; BH3 interacting domain death agonist" ID="ID_1952973594" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RCHY1: 2.04-fold Up; FDR = 1.35e-08; PValue = 6.04e-10; mean CPM = 25.49; ring finger and CHY zinc finger domain containing 1" ID="ID_1867691306" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZMAT3: 1.69-fold Up; FDR = 1.51e-07; PValue = 8.85e-09; mean CPM = 49.10; zinc finger, matrin type 3" ID="ID_1655022446" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNG2: 1.58-fold Up; FDR = 2.55e-07; PValue = 1.56e-08; mean CPM = 45.06; cyclin G2" ID="ID_1498264031" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_763206839" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THBS1: 2.74-fold Down; FDR = 1.68e-06; PValue = 1.28e-07; mean CPM = 25785; thrombospondin 1" ID="ID_1213446153" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1: 5.76-fold Down; FDR = 6.73e-06; PValue = 6.04e-07; mean CPM = 1.536; insulin-like growth factor 1 (somatomedin C)" ID="ID_1080840858" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGFBP3: 2.13-fold Down; FDR = 6.87e-06; PValue = 6.19e-07; mean CPM = 3776; insulin-like growth factor binding protein 3" ID="ID_1844889439" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TSC2: 1.44-fold Down; FDR = 1e-05; PValue = 9.42e-07; mean CPM = 124.0; tuberous sclerosis 2" ID="ID_971094998" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNG1: 1.38-fold Up; FDR = 6.77e-05; PValue = 8.01e-06; mean CPM = 149.9; cyclin G1" ID="ID_1502691043" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP53I3: 1.62-fold Down; FDR = 0.000105; PValue = 1.3e-05; mean CPM = 21.59; tumor protein p53 inducible protein 3" ID="ID_687991685" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SESN2: 1.54-fold Up; FDR = 0.000955; PValue = 0.00016; mean CPM = 76.08; sestrin 2" ID="ID_1492208685" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHISA5: 1.45-fold Up; FDR = 0.00115; PValue = 0.000198; mean CPM = 12.01; shisa homolog 5 (Xenopus laevis)" ID="ID_552399146" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHISA5: 1.3-fold Up; FDR = 0.00148; PValue = 0.000264; mean CPM = 172.3; shisa family member 5" ID="ID_927490199" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SERPINE1: 1.58-fold Down; FDR = 0.00232; PValue = 0.000438; mean CPM = 5294; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1" ID="ID_1606963946" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SESN3: 1.52-fold Up; FDR = 0.00256; PValue = 0.000491; mean CPM = 443.2; sestrin 3" ID="ID_380375798" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD82: 1.42-fold Up; FDR = 0.0045; PValue = 0.00094; mean CPM = 43.78; CD82 molecule" ID="ID_400960945" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MDM2: 1.32-fold Up; FDR = 0.00555; PValue = 0.00119; mean CPM = 148.6; Uncharacterized protein" ID="ID_1936322338" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GADD45B: 1.49-fold Down; FDR = 0.0082; PValue = 0.00187; mean CPM = 175.6; growth arrest and DNA-damage-inducible, beta" ID="ID_1455496529" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GTSE1: 1.58-fold Down; FDR = 0.00855; PValue = 0.00196; mean CPM = 10.71; G-2 and S-phase expressed 1" ID="ID_1805180978" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SIAH1: 1.32-fold Up; FDR = 0.0104; PValue = 0.00245; mean CPM = 14.33; seven in absentia homolog 1 (Drosophila)" ID="ID_985489811" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GADD45G: 1.49-fold Up; FDR = 0.0173; PValue = 0.00444; mean CPM = 12.01; growth arrest and DNA-damage-inducible, gamma" ID="ID_1894385386" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK2: 1.23-fold Down; FDR = 0.0194; PValue = 0.00507; mean CPM = 36.76; cyclin-dependent kinase 2" ID="ID_1717702028" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHEK2: 1.38-fold Up; FDR = 0.0228; PValue = 0.00613; mean CPM = 20.56; checkpoint kinase 2" ID="ID_1864831878" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GADD45A: 1.22-fold Up; FDR = 0.0344; PValue = 0.00989; mean CPM = 127.8; growth arrest and DNA-damage-inducible, alpha" ID="ID_400847726" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP73: 2.3-fold Down; FDR = 0.0601; PValue = 0.0192; mean CPM = 1.058; tumor protein p73" ID="ID_167491933" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNB1: 1.39-fold Down; FDR = 0.0958; PValue = 0.0333; mean CPM = 44.87; cyclin B1" ID="ID_1018776762" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND1: 1.17-fold Up; FDR = 0.121; PValue = 0.0443; mean CPM = 867.3; cyclin D1" ID="ID_496442063" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTEN: 1.14-fold Up; FDR = 0.166; PValue = 0.065; mean CPM = 89.60; phosphatase and tensin homolog" ID="ID_230295534" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LRDD: 1.2-fold Down; FDR = 0.207; PValue = 0.0859; mean CPM = 25.64; leucine-rich repeats and death domain containing" ID="ID_326800949" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PERP: 1.32-fold Down; FDR = 0.208; PValue = 0.0863; mean CPM = 3.279; Uncharacterized protein" ID="ID_1831216722" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000039103: 1.67-fold Down; FDR = 0.221; PValue = 0.0927; mean CPM = 1.310; Uncharacterized protein" ID="ID_256421820" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNB2: 1.24-fold Down; FDR = 0.237; PValue = 0.101; mean CPM = 15.12; cyclin B2" ID="ID_160520284" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNE1: 1.2-fold Up; FDR = 0.278; PValue = 0.123; mean CPM = 6.609; cyclin E1" ID="ID_508350487" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1A: 1.16-fold Down; FDR = 0.28; PValue = 0.124; mean CPM = 363.2; Cyclin-dependent kinase inhibitor 1; Uncharacterized protein" ID="ID_368820171" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK6: 1.18-fold Down; FDR = 0.301; PValue = 0.136; mean CPM = 26.51; cyclin-dependent kinase 6" ID="ID_487465326" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SFN: 1.69-fold Down; FDR = 0.304; PValue = 0.138; mean CPM = 1.084; stratifin" ID="ID_310805339" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND2: 1.2-fold Up; FDR = 0.335; PValue = 0.155; mean CPM = 76.91; cyclin D2" ID="ID_88043891" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF10B: 1.13-fold Down; FDR = 0.343; PValue = 0.16; mean CPM = 40.59; tumor necrosis factor receptor superfamily, member 10b" ID="ID_1758160412" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP53: 1.11-fold Down; FDR = 0.364; PValue = 0.172; mean CPM = 33.25; tumor protein p53" ID="ID_1390907540" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EI24: 1.11-fold Down; FDR = 0.408; PValue = 0.199; mean CPM = 19.02; etoposide induced 2.4 mRNA" ID="ID_506158095" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STEAP3: 1.11-fold Down; FDR = 0.449; PValue = 0.224; mean CPM = 154.9; STEAP family member 3" ID="ID_475964389" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAI1: 1.74-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 0.8744; brain-specific angiogenesis inhibitor 1" ID="ID_281990642" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DDB2: 1.07-fold Down; FDR = 0.626; PValue = 0.349; mean CPM = 69.08; damage-specific DNA binding protein 2, 48kDa" ID="ID_1144007409" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MDM4: 1.07-fold Up; FDR = 0.632; PValue = 0.354; mean CPM = 28.16; Mdm4 p53 binding protein homolog (mouse)" ID="ID_1780693688" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATM: 1.06-fold Down; FDR = 0.67; PValue = 0.383; mean CPM = 65.17; ataxia telangiectasia mutated" ID="ID_712639264" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RRM2: 1.18-fold Down; FDR = 0.675; PValue = 0.387; mean CPM = 63.27; ribonucleotide reductase M2" ID="ID_1738918989" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SERPINB5: 1.44-fold Down; FDR = 0.716; PValue = 0.42; mean CPM = 0.8736; Peptidase inhibitor 5; Uncharacterized protein" ID="ID_700228662" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_789509444" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPRM: 1.38-fold Down; FDR = 0.807; PValue = 0.504; mean CPM = 0.8749; reprimo, TP53 dependent G2 arrest mediator candidate" ID="ID_280936719" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAX: 1.05-fold Up; FDR = 0.809; PValue = 0.506; mean CPM = 162.4; Uncharacterized protein" ID="ID_69384635" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APAF1: 1.05-fold Down; FDR = 0.837; PValue = 0.543; mean CPM = 32.11; apoptotic peptidase activating factor 1" ID="ID_208935685" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYCS: 1.05-fold Up; FDR = 0.854; PValue = 0.565; mean CPM = 93.43; cytochrome c, somatic" ID="ID_830874856" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000040219: 1.08-fold Up; FDR = 0.86; PValue = 0.575; mean CPM = 8.818; Uncharacterized protein" ID="ID_1458059888" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPM1D: 1.05-fold Up; FDR = 0.884; PValue = 0.604; mean CPM = 14.38; Protein phosphatase 1D; Uncharacterized protein" ID="ID_1446553120" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK4: 1.04-fold Up; FDR = 0.899; PValue = 0.626; mean CPM = 65.45; cyclin-dependent kinase 4" ID="ID_798949146" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK1: 1.07-fold Up; FDR = 0.908; PValue = 0.682; mean CPM = 14.72; Uncharacterized protein" ID="ID_1498589164" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RFWD2: 1.03-fold Up; FDR = 0.911; PValue = 0.705; mean CPM = 36.86; ring finger and WD repeat domain 2" ID="ID_170726222" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BBC3: 1.04-fold Down; FDR = 0.948; PValue = 0.77; mean CPM = 7.586; BCL2 binding component 3" ID="ID_1816946368" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNE2: 1.05-fold Up; FDR = 0.962; PValue = 0.796; mean CPM = 6.415; cyclin E2" ID="ID_558684404" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000009289: 1.07-fold Up; FDR = 0.963; PValue = 0.798; mean CPM = 2.536; Uncharacterized protein" ID="ID_1985141311" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PERP: 1.08-fold Down; FDR = 1; PValue = 0.864; mean CPM = 0.9252; PERP, TP53 apoptosis effector" ID="ID_1445196045" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP9: 1.01-fold Up; FDR = 1; PValue = 0.908; mean CPM = 19.86; caspase 9, apoptosis-related cysteine peptidase" ID="ID_1931053122" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SESN1: 1.01-fold Up; FDR = 1; PValue = 0.939; mean CPM = 8.816; sestrin 1" ID="ID_1793032407" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="CD40: FDR = 5.7e-06, PValue = 4.33e-06" ID="ID_1585113185" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="ICAM1: 24.6-fold Up; FDR = 2.39e-17; PValue = 1.64e-19; mean CPM = 232.4; intercellular adhesion molecule 1" ID="ID_1493568264" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TANK: 1.77-fold Up; FDR = 3.82e-13; PValue = 5.66e-15; mean CPM = 62.24; TRAF family member-associated NFKB activator" ID="ID_389221414" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_1136538906" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1122560162" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_812586035" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8IP1: 1.53-fold Down; FDR = 4.63e-07; PValue = 3.04e-08; mean CPM = 28.91; mitogen-activated protein kinase 8 interacting protein 1" ID="ID_490748771" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_514268471" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1198183251" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF1: 1.51-fold Up; FDR = 5.28e-06; PValue = 4.58e-07; mean CPM = 22.13; activating transcription factor 1" ID="ID_1677749432" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K3: 1.45-fold Down; FDR = 7.01e-06; PValue = 6.34e-07; mean CPM = 180.1; mitogen-activated protein kinase kinase 3" ID="ID_1160975615" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8IP3: 1.77-fold Down; FDR = 1.28e-05; PValue = 1.24e-06; mean CPM = 65.23; mitogen-activated protein kinase 8 interacting protein 3" ID="ID_1794588825" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1747984211" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF1: 2.6-fold Down; FDR = 1.48e-05; PValue = 1.46e-06; mean CPM = 20.19; TNF receptor-associated factor 1" ID="ID_1406089454" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFAIP3: 1.79-fold Up; FDR = 3.14e-05; PValue = 3.34e-06; mean CPM = 52.47; tumor necrosis factor, alpha-induced protein 3" ID="ID_624748128" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_377621098" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40: 2.76-fold Up; FDR = 0.00039; PValue = 5.79e-05; mean CPM = 9.139; CD40 molecule, TNF receptor superfamily member 5" ID="ID_1751389409" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_1512883066" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DUSP1: 1.39-fold Down; FDR = 0.00173; PValue = 0.000315; mean CPM = 355.2; dual specificity phosphatase 1" ID="ID_753176467" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK3: 2.31-fold Up; FDR = 0.00186; PValue = 0.000342; mean CPM = 2.154; Janus kinase 3" ID="ID_483543659" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1301472304" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K14: 1.47-fold Down; FDR = 0.00704; PValue = 0.00157; mean CPM = 9.470; mitogen-activated protein kinase kinase kinase 14" ID="ID_1643875690" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K3: 1.26-fold Down; FDR = 0.00786; PValue = 0.00178; mean CPM = 38.85; mitogen-activated protein kinase kinase kinase 3" ID="ID_1227280745" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_31370735" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1001198383" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKAP: 1.19-fold Down; FDR = 0.0434; PValue = 0.013; mean CPM = 50.22; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein" ID="ID_913563156" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_937370319" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_1701333619" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_159123729" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_665873748" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8IP2: 1.29-fold Down; FDR = 0.543; PValue = 0.289; mean CPM = 2.167; mitogen-activated protein kinase 8 interacting protein 2" ID="ID_426056068" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF3: 1.07-fold Up; FDR = 0.611; PValue = 0.338; mean CPM = 34.56; TNF receptor-associated factor 3" ID="ID_833068190" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPKAPK2: 1.06-fold Down; FDR = 0.733; PValue = 0.435; mean CPM = 82.16; mitogen-activated protein kinase-activated protein kinase 2" ID="ID_51125460" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_828753089" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FCER2: 1.41-fold Up; FDR = 0.864; PValue = 0.58; mean CPM = 0.8258; Fc fragment of IgE, low affinity II, receptor for (CD23)" ID="ID_1753393530" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1042577213" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K2: 1.03-fold Up; FDR = 0.924; PValue = 0.73; mean CPM = 40.64; mitogen-activated protein kinase kinase kinase 2" ID="ID_1801879216" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_454152870" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_1125176992" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF3IP2: 1.01-fold Down; FDR = 1; PValue = 0.913; mean CPM = 29.19; TRAF3 interacting protein 2" ID="ID_1811933286" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40LG: 1.01-fold Down; FDR = 1; PValue = 0.982; mean CPM = 0.8653; CD40 ligand" ID="ID_776120734" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="WNT signaling: FDR = 1.3e-05, PValue = 1.01e-05" ID="ID_1660145882" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="NFATC4: 1.85-fold Down; FDR = 1.13e-11; PValue = 2.37e-13; mean CPM = 51.58; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4" ID="ID_1792684647" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD2: 2.27-fold Down; FDR = 5e-11; PValue = 1.24e-12; mean CPM = 20.66; frizzled homolog 2 (Drosophila)" ID="ID_1645766607" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND3: 2.27-fold Down; FDR = 8.38e-11; PValue = 2.15e-12; mean CPM = 86.90; cyclin D3" ID="ID_1260524366" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRICKLE2: 2.93-fold Down; FDR = 3.36e-09; PValue = 1.3e-10; mean CPM = 14.29; prickle homolog 2 (Drosophila)" ID="ID_1937207835" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAMK2D: 1.54-fold Up; FDR = 4.06e-08; PValue = 2.07e-09; mean CPM = 51.52; calcium/calmodulin-dependent protein kinase II delta" ID="ID_13748646" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPARD: 1.76-fold Down; FDR = 1.58e-07; PValue = 9.27e-09; mean CPM = 32.10; peroxisome proliferator-activated receptor delta" ID="ID_1869109403" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCB1: 1.71-fold Up; FDR = 1.31e-06; PValue = 9.73e-08; mean CPM = 34.36; phospholipase C, beta 1 (phosphoinositide-specific)" ID="ID_109540557" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1293871997" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC3: 1.68-fold Down; FDR = 2.72e-06; PValue = 2.19e-07; mean CPM = 13.98; ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)" ID="ID_144629898" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD7: 1.62-fold Down; FDR = 5.66e-06; PValue = 4.95e-07; mean CPM = 34.19; frizzled homolog 7 (Drosophila)" ID="ID_1436557766" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTNNBIP1: 1.62-fold Down; FDR = 6.5e-06; PValue = 5.82e-07; mean CPM = 12.40; catenin, beta interacting protein 1" ID="ID_135942247" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DKK1: 1.73-fold Up; FDR = 8.46e-06; PValue = 7.83e-07; mean CPM = 206.3; dickkopf homolog 1 (Xenopus laevis)" ID="ID_1523978950" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT5A: 1.65-fold Down; FDR = 2.5e-05; PValue = 2.59e-06; mean CPM = 136.4; wingless-type MMTV integration site family, member 5A" ID="ID_202220270" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R1B: 1.39-fold Down; FDR = 4.37e-05; PValue = 4.86e-06; mean CPM = 233.1; protein phosphatase 2, regulatory subunit A, beta" ID="ID_1906694594" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000009315: 1.44-fold Down; FDR = 4.44e-05; PValue = 4.94e-06; mean CPM = 22.79" ID="ID_152957353" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AXIN2: 3.75-fold Down; FDR = 6.09e-05; PValue = 7.1e-06; mean CPM = 2.690; axin 2" ID="ID_1526226444" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRICKLE1: 1.61-fold Up; FDR = 7.19e-05; PValue = 8.57e-06; mean CPM = 16.83; prickle homolog 1 (Drosophila)" ID="ID_131121986" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R5A: 1.45-fold Up; FDR = 0.000141; PValue = 1.83e-05; mean CPM = 21.64; protein phosphatase 2, regulatory subunit B', alpha" ID="ID_1914375015" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACA: 1.36-fold Down; FDR = 0.000167; PValue = 2.22e-05; mean CPM = 37.75; protein kinase, cAMP-dependent, catalytic, alpha" ID="ID_1071877285" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2CB: 1.35-fold Up; FDR = 0.000215; PValue = 2.96e-05; mean CPM = 59.68; protein phosphatase 2, catalytic subunit, beta isozyme" ID="ID_1528689626" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCB4: 1.75-fold Down; FDR = 0.00025; PValue = 3.52e-05; mean CPM = 6.730; phospholipase C, beta 4" ID="ID_1735032574" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LRP5: 1.49-fold Down; FDR = 0.000262; PValue = 3.71e-05; mean CPM = 198.7; Uncharacterized protein" ID="ID_923207240" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP3CA: 1.55-fold Up; FDR = 0.0003; PValue = 4.32e-05; mean CPM = 40.21; protein phosphatase 3, catalytic subunit, alpha isozyme" ID="ID_1785388029" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC2: 4.03-fold Down; FDR = 0.000346; PValue = 5.06e-05; mean CPM = 1.347; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2" ID="ID_1275150561" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD9: 2.74-fold Down; FDR = 0.000408; PValue = 6.1e-05; mean CPM = 1.789; frizzled homolog 9 (Drosophila)" ID="ID_1517545512" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBL1Y: 1.41-fold Up; FDR = 0.000492; PValue = 7.5e-05; mean CPM = 32.35; F-box-like/WD repeat-containing protein TBL1Y" ID="ID_1123043256" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD3: 1.38-fold Up; FDR = 0.000573; PValue = 8.94e-05; mean CPM = 114.9; SMAD family member 3" ID="ID_1773425084" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT1: 7.1-fold Down; FDR = 0.000659; PValue = 0.000105; mean CPM = 2.664; wingless-type MMTV integration site family, member 1" ID="ID_985048680" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAMK2A: 2.29-fold Down; FDR = 0.00124; PValue = 0.000217; mean CPM = 2.001; calcium/calmodulin-dependent protein kinase II alpha" ID="ID_715262983" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RUVBL1: 1.33-fold Up; FDR = 0.00132; PValue = 0.000232; mean CPM = 57.28; RuvB-like 1 (E. coli)" ID="ID_1386733515" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DVL3: 1.29-fold Down; FDR = 0.00157; PValue = 0.00028; mean CPM = 67.95; dishevelled, dsh homolog 3 (Drosophila)" ID="ID_1332399098" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PORCN: 1.5-fold Down; FDR = 0.00213; PValue = 0.000399; mean CPM = 7.981; porcupine homolog (Drosophila)" ID="ID_1065097446" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD4: 1.83-fold Up; FDR = 0.00258; PValue = 0.000495; mean CPM = 4.537; frizzled homolog 4 (Drosophila)" ID="ID_1869268243" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHOA: 1.28-fold Down; FDR = 0.00295; PValue = 0.000575; mean CPM = 277.8; ras homolog gene family, member A" ID="ID_1563195747" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKX: 1.31-fold Down; FDR = 0.00331; PValue = 0.000658; mean CPM = 24.94; protein kinase, X-linked" ID="ID_1202148454" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R5D: 1.27-fold Down; FDR = 0.00482; PValue = 0.00101; mean CPM = 35.61; protein phosphatase 2, regulatory subunit B', delta" ID="ID_545871360" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VANGL1: 1.33-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 16.07; VANGL planar cell polarity protein 1" ID="ID_1420003112" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAMK2B: 3.82-fold Down; FDR = 0.00536; PValue = 0.00115; mean CPM = 1.542; calcium/calmodulin-dependent protein kinase II beta" ID="ID_1452806289" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_663929542" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT7A: 3.46-fold Down; FDR = 0.00638; PValue = 0.0014; mean CPM = 1.036; wingless-type MMTV integration site family, member 7A" ID="ID_1210193227" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT10A: 4.08-fold Down; FDR = 0.00805; PValue = 0.00183; mean CPM = 0.9138; wingless-type MMTV integration site family, member 10A" ID="ID_1726377502" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DAAM2: 1.27-fold Down; FDR = 0.00807; PValue = 0.00184; mean CPM = 130.1; dishevelled associated activator of morphogenesis 2" ID="ID_71140896" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT5B: 1.58-fold Down; FDR = 0.00866; PValue = 0.002; mean CPM = 7.832; wingless-type MMTV integration site family, member 5B" ID="ID_1999289900" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SIAH1: 1.32-fold Up; FDR = 0.0104; PValue = 0.00245; mean CPM = 14.33; seven in absentia homolog 1 (Drosophila)" ID="ID_1799045935" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CUL1: 1.24-fold Up; FDR = 0.0104; PValue = 0.00247; mean CPM = 106.1; cullin 1" ID="ID_1059806215" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTBP1: 1.23-fold Down; FDR = 0.0119; PValue = 0.00287; mean CPM = 100.6; C-terminal binding protein 1" ID="ID_1199217228" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSNK2A2: 1.28-fold Up; FDR = 0.0129; PValue = 0.00314; mean CPM = 19.86; casein kinase 2, alpha prime polypeptide" ID="ID_1811769015" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SFRP2: 1.53-fold Down; FDR = 0.0136; PValue = 0.00334; mean CPM = 373.9; secreted frizzled-related protein 2" ID="ID_405129191" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT10B: 3.1-fold Down; FDR = 0.0148; PValue = 0.00369; mean CPM = 1.086; wingless-type MMTV integration site family, member 10B" ID="ID_1646428420" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTBP2: 1.23-fold Up; FDR = 0.0166; PValue = 0.00423; mean CPM = 49.75; C-terminal binding protein 2" ID="ID_1447665808" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AC012652.1: 1.23-fold Down; FDR = 0.0201; PValue = 0.0053; mean CPM = 33.80; Calcium-binding protein p22 (Calcium-binding protein CHP)(Calcineurin homologous protein)(Calcineurin B homolog)" ID="ID_1213829635" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFAT5: 1.21-fold Up; FDR = 0.0273; PValue = 0.00754; mean CPM = 113.0; nuclear factor of activated T-cells 5, tonicity-responsive" ID="ID_840400036" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC2: 2.96-fold Up; FDR = 0.0309; PValue = 0.00872; mean CPM = 0.9737; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)" ID="ID_1561937604" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD2: 1.2-fold Up; FDR = 0.034; PValue = 0.00976; mean CPM = 57.10; SMAD family member 2" ID="ID_348216989" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TCF7: 1.72-fold Down; FDR = 0.0376; PValue = 0.011; mean CPM = 4.279; transcription factor 7 (T-cell specific, HMG-box)" ID="ID_1009132590" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACYBP: 1.2-fold Up; FDR = 0.0455; PValue = 0.0138; mean CPM = 51.35; Calcyclin-binding protein isoform 1; Uncharacterized protein" ID="ID_1746079953" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCB2: 3.68-fold Down; FDR = 0.0481; PValue = 0.0147; mean CPM = 1.557; Uncharacterized protein" ID="ID_1401436571" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTNNB1: 1.2-fold Up; FDR = 0.0498; PValue = 0.0153; mean CPM = 558.3; catenin (cadherin-associated protein), beta 1, 88kDa" ID="ID_1239853158" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APC2: 1.29-fold Down; FDR = 0.0505; PValue = 0.0155; mean CPM = 8.899; adenomatosis polyposis coli 2" ID="ID_821145480" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT4: 1.52-fold Down; FDR = 0.0525; PValue = 0.0163; mean CPM = 13.66; wingless-type MMTV integration site family, member 4" ID="ID_1035583858" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_897067322" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TCF7L1: 1.2-fold Down; FDR = 0.0783; PValue = 0.0262; mean CPM = 25.11; transcription factor 7-like 1 (T-cell specific, HMG-box)" ID="ID_463104856" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FBXW11: 1.16-fold Up; FDR = 0.106; PValue = 0.0378; mean CPM = 64.90; F-box and WD repeat domain containing 11" ID="ID_443819222" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R5E: 1.17-fold Up; FDR = 0.112; PValue = 0.04; mean CPM = 30.87; Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform; Uncharacterized protein" ID="ID_119399589" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND1: 1.17-fold Up; FDR = 0.121; PValue = 0.0443; mean CPM = 867.3; cyclin D1" ID="ID_1244134056" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_575602243" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000024051: 1.19-fold Up; FDR = 0.136; PValue = 0.0509; mean CPM = 16.04; Uncharacterized protein" ID="ID_735800139" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_791889982" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VANGL2: 1.48-fold Down; FDR = 0.143; PValue = 0.0542; mean CPM = 2.357; vang-like 2 (van gogh, Drosophila)" ID="ID_790793924" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_99938020" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD1: 1.23-fold Down; FDR = 0.154; PValue = 0.0592; mean CPM = 31.65; frizzled homolog 1 (Drosophila)" ID="ID_1235983040" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NKD1: 2.25-fold Down; FDR = 0.161; PValue = 0.0628; mean CPM = 0.9036; naked cuticle homolog 1 (Drosophila)" ID="ID_1835335984" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ROCK2: 1.14-fold Up; FDR = 0.166; PValue = 0.065; mean CPM = 247.7; Rho-associated, coiled-coil containing protein kinase 2" ID="ID_1107167723" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SKP1: 1.14-fold Up; FDR = 0.176; PValue = 0.07; mean CPM = 88.20; S-phase kinase-associated protein 1" ID="ID_518570214" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT3A: 2.28-fold Down; FDR = 0.2; PValue = 0.0823; mean CPM = 0.8811; wingless-type MMTV integration site family, member 3A" ID="ID_1836802245" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000041158: 1.15-fold Up; FDR = 0.216; PValue = 0.0905; mean CPM = 24.28; Uncharacterized protein" ID="ID_1044263896" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSNK1E: 1.13-fold Down; FDR = 0.221; PValue = 0.0928; mean CPM = 85.29; casein kinase 1, epsilon" ID="ID_534758271" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSEN1: 1.12-fold Up; FDR = 0.233; PValue = 0.0992; mean CPM = 62.12; presenilin 1" ID="ID_1251629468" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT3: 1.4-fold Up; FDR = 0.304; PValue = 0.138; mean CPM = 1.843; wingless-type MMTV integration site family, member 3" ID="ID_878231193" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EP300: 1.11-fold Up; FDR = 0.312; PValue = 0.142; mean CPM = 162.8; E1A binding protein p300" ID="ID_510529677" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND2: 1.2-fold Up; FDR = 0.335; PValue = 0.155; mean CPM = 76.91; cyclin D2" ID="ID_481955737" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD6: 1.11-fold Down; FDR = 0.347; PValue = 0.162; mean CPM = 39.10; frizzled homolog 6 (Drosophila)" ID="ID_177374623" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP53: 1.11-fold Down; FDR = 0.364; PValue = 0.172; mean CPM = 33.25; tumor protein p53" ID="ID_230300215" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APC: 1.1-fold Down; FDR = 0.367; PValue = 0.174; mean CPM = 127.5; adenomatous polyposis coli" ID="ID_773162628" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R5C: 1.14-fold Up; FDR = 0.391; PValue = 0.189; mean CPM = 54.95; protein phosphatase 2, regulatory subunit B', gamma" ID="ID_105202961" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD5: 1.34-fold Down; FDR = 0.405; PValue = 0.197; mean CPM = 2.107; frizzled homolog 5 (Drosophila)" ID="ID_1537056558" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BTRC: 1.11-fold Down; FDR = 0.413; PValue = 0.202; mean CPM = 17.40; beta-transducin repeat containing" ID="ID_910065662" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RBX1: 1.09-fold Up; FDR = 0.413; PValue = 0.202; mean CPM = 67.97; ring-box 1" ID="ID_434269918" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NKD2: 1.75-fold Up; FDR = 0.422; PValue = 0.207; mean CPM = 0.9072; naked cuticle homolog 2 (Drosophila)" ID="ID_1930294216" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DAAM1: 1.11-fold Down; FDR = 0.457; PValue = 0.229; mean CPM = 23.67; dishevelled associated activator of morphogenesis 1" ID="ID_1936777172" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC1: 1.11-fold Down; FDR = 0.457; PValue = 0.23; mean CPM = 19.06; Uncharacterized protein" ID="ID_1172840407" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DKK4: 1.7-fold Up; FDR = 0.476; PValue = 0.242; mean CPM = 0.9028; dickkopf homolog 4 (Xenopus laevis)" ID="ID_894339312" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT9A: 1.43-fold Down; FDR = 0.505; PValue = 0.262; mean CPM = 2.172; wingless-type MMTV integration site family, member 9A" ID="ID_1295179943" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP3CB: 1.08-fold Up; FDR = 0.514; PValue = 0.268; mean CPM = 76.44; protein phosphatase 3, catalytic subunit, beta isozyme" ID="ID_740474999" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WIF1: 1.61-fold Down; FDR = 0.541; PValue = 0.287; mean CPM = 0.8746; WNT inhibitory factor 1" ID="ID_379315944" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCG: 1.47-fold Down; FDR = 0.609; PValue = 0.336; mean CPM = 0.9297; protein kinase C, gamma" ID="ID_1966672210" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT2B: 1.29-fold Down; FDR = 0.621; PValue = 0.345; mean CPM = 1.575; wingless-type MMTV integration site family, member 2B" ID="ID_365727891" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AXIN1: 1.06-fold Up; FDR = 0.661; PValue = 0.376; mean CPM = 66.56; axin 1" ID="ID_1776450150" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LEF1: 1.2-fold Up; FDR = 0.691; PValue = 0.4; mean CPM = 2.488; lymphoid enhancer-binding factor 1" ID="ID_7278100" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DVL2: 1.06-fold Up; FDR = 0.708; PValue = 0.414; mean CPM = 30.54; dishevelled, dsh homolog 2 (Drosophila)" ID="ID_1908431785" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCB: 1.86-fold Up; FDR = 0.727; PValue = 0.43; mean CPM = 0.8705; protein kinase C, beta" ID="ID_999445797" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBL1XR1: 1.06-fold Up; FDR = 0.729; PValue = 0.431; mean CPM = 74.21; transducin (beta)-like 1 X-linked receptor 1" ID="ID_1699352465" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACG: 1.51-fold Down; FDR = 0.795; PValue = 0.491; mean CPM = 0.8026; protein kinase, cAMP-dependent, catalytic, gamma" ID="ID_1682792055" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2CA: 1.05-fold Up; FDR = 0.8; PValue = 0.497; mean CPM = 62.78; protein phosphatase 2, catalytic subunit, alpha isozyme" ID="ID_1001025141" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSNK1A1L: 1.31-fold Up; FDR = 0.806; PValue = 0.502; mean CPM = 0.9242; casein kinase 1, alpha 1-like" ID="ID_1562216085" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT16: 1.27-fold Down; FDR = 0.857; PValue = 0.571; mean CPM = 0.9003; wingless-type MMTV integration site family, member 16" ID="ID_1372156309" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP7: 1.39-fold Down; FDR = 0.89; PValue = 0.613; mean CPM = 0.8356; Uncharacterized protein" ID="ID_325540310" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT11: 1.18-fold Up; FDR = 0.903; PValue = 0.641; mean CPM = 1.340; wingless-type MMTV integration site family, member 11" ID="ID_1873017199" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DKK2: 1.21-fold Up; FDR = 0.903; PValue = 0.645; mean CPM = 0.9269; dickkopf homolog 2 (Xenopus laevis)" ID="ID_858992121" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOSL1: 1.04-fold Up; FDR = 0.903; PValue = 0.657; mean CPM = 64.19; FOS-like antigen 1" ID="ID_1737454171" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000021684: 1.44-fold Up; FDR = 0.903; PValue = 0.662; mean CPM = 0.8513; Uncharacterized protein" ID="ID_960543332" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD4: 1.03-fold Down; FDR = 0.906; PValue = 0.666; mean CPM = 43.02; SMAD family member 4" ID="ID_474609202" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOX17: 1.19-fold Down; FDR = 0.906; PValue = 0.668; mean CPM = 0.8003; SRY (sex determining region Y)-box 17" ID="ID_1145637643" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACB: 1.03-fold Up; FDR = 0.911; PValue = 0.694; mean CPM = 30.10; protein kinase, cAMP-dependent, catalytic, beta" ID="ID_129408477" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SFRP5: 1.18-fold Down; FDR = 0.917; PValue = 0.718; mean CPM = 0.8162; secreted frizzled-related protein 5" ID="ID_809378463" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CER1: 1.24-fold Down; FDR = 0.92; PValue = 0.722; mean CPM = 0.8049; Cerberus-related protein; Uncharacterized protein" ID="ID_1640522900" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SENP2: 1.02-fold Up; FDR = 0.925; PValue = 0.732; mean CPM = 51.25; SUMO1/sentrin/SMT3 specific peptidase 2" ID="ID_291531602" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTBP2: 1.24-fold Up; FDR = 0.934; PValue = 0.746; mean CPM = 0.8168; C-terminal binding protein 2" ID="ID_728237266" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXXC4: 1.29-fold Down; FDR = 0.939; PValue = 0.753; mean CPM = 0.8071; CXXC finger 4" ID="ID_1941633538" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AC130454.2: 1.18-fold Up; FDR = 0.942; PValue = 0.76; mean CPM = 0.8360; Calcineurin B homologous protein 2 (Hepatocellular carcinoma-associated antigen 520)" ID="ID_1413624944" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SFRP4: 1.39-fold Up; FDR = 0.948; PValue = 0.771; mean CPM = 0.8499; Macaca mulatta secreted frizzled-related protein 4 (SFRP4), mRNA." ID="ID_500096106" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC3: 1.03-fold Down; FDR = 0.952; PValue = 0.78; mean CPM = 13.31; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3" ID="ID_442830804" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSNK2B: 1.02-fold Down; FDR = 0.956; PValue = 0.787; mean CPM = 77.24; Casein kinase II subunit beta (CK II beta)(Phosvitin)(Protein G5a)" ID="ID_335874312" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LRP6: 1.02-fold Down; FDR = 0.962; PValue = 0.796; mean CPM = 85.24; low density lipoprotein receptor-related protein 6" ID="ID_226010809" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_485549244" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_1742770761" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SFRP1: 1.02-fold Up; FDR = 0.972; PValue = 0.814; mean CPM = 307.1; secreted frizzled-related protein 1" ID="ID_349508843" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT8B: 1.21-fold Down; FDR = 0.987; PValue = 0.838; mean CPM = 0.8506; wingless-type MMTV integration site family, member 8B" ID="ID_1043109073" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREBBP: 1.01-fold Down; FDR = 0.993; PValue = 0.847; mean CPM = 137.7; CREB binding protein" ID="ID_109331287" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT2: 1.07-fold Down; FDR = 1; PValue = 0.888; mean CPM = 0.8103; wingless-type MMTV integration site family member 2" ID="ID_423073820" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R5B: 1.01-fold Down; FDR = 1; PValue = 0.898; mean CPM = 92.91; protein phosphatase 2, regulatory subunit B', beta" ID="ID_867202741" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD3: 1.03-fold Up; FDR = 1; PValue = 0.903; mean CPM = 1.636; frizzled homolog 3 (Drosophila)" ID="ID_1192863530" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD10: 1.04-fold Down; FDR = 1; PValue = 0.919; mean CPM = 0.8435; frizzled homolog 10 (Drosophila)" ID="ID_1703395302" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHD8: 1.01-fold Down; FDR = 1; PValue = 0.921; mean CPM = 155.1; chromodomain helicase DNA binding protein 8" ID="ID_1383281126" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT6: 1.13-fold Down; FDR = 1; PValue = 0.956; mean CPM = 0.8230; wingless-type MMTV integration site family, member 6" ID="ID_991352135" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLK: No Change; FDR = 1; PValue = 0.97; mean CPM = 11.78; nemo-like kinase" ID="ID_1205788438" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT9B: 1.03-fold Up; FDR = 1; PValue = 0.991; mean CPM = 0.8041; wingless-type MMTV integration site family, member 9B" ID="ID_1533278714" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-1R1: FDR = 1.79e-05, PValue = 1.42e-05" ID="ID_1212746895" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CCL2: 24.6-fold Up; FDR = 1.83e-15; PValue = 1.69e-17; mean CPM = 668.2; Macaca mulatta chemokine (C-C motif) ligand 2 (CCL2), mRNA." ID="ID_1811570150" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PELI1: 2-fold Up; FDR = 5.5e-09; PValue = 2.23e-10; mean CPM = 30.48; pellino homolog 1 (Drosophila)" ID="ID_455251963" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK4: 1.8-fold Up; FDR = 3.31e-08; PValue = 1.64e-09; mean CPM = 12.89; interleukin-1 receptor-associated kinase 4" ID="ID_1241697694" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1734612161" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1761051737" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_441762588" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K3: 1.45-fold Down; FDR = 7.01e-06; PValue = 6.34e-07; mean CPM = 180.1; mitogen-activated protein kinase kinase 3" ID="ID_1849246648" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1681636208" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1R1: 1.6-fold Up; FDR = 3.35e-05; PValue = 3.61e-06; mean CPM = 123.7; interleukin 1 receptor, type I" ID="ID_272228419" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP2: 1.45-fold Up; FDR = 0.000179; PValue = 2.4e-05; mean CPM = 65.31; TGF-beta activated kinase 1/MAP3K7 binding protein 2" ID="ID_572139687" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP3: 1.5-fold Up; FDR = 0.000276; PValue = 3.92e-05; mean CPM = 11.67; TGF-beta activated kinase 1/MAP3K7 binding protein 3" ID="ID_1232249878" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF2: 1.34-fold Up; FDR = 0.000403; PValue = 6.01e-05; mean CPM = 39.83; activating transcription factor 2" ID="ID_1424142009" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_113487599" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TOLLIP: 1.36-fold Down; FDR = 0.000551; PValue = 8.57e-05; mean CPM = 28.79; Uncharacterized protein" ID="ID_41025477" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="REL: 1.46-fold Down; FDR = 0.00272; PValue = 0.000526; mean CPM = 10.17; v-rel avian reticuloendotheliosis viral oncogene homolog" ID="ID_834193751" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG1: 1.31-fold Down; FDR = 0.00352; PValue = 0.000707; mean CPM = 53.66; phospholipase C, gamma 1" ID="ID_1875172388" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_71094536" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK3: 1.54-fold Up; FDR = 0.00653; PValue = 0.00144; mean CPM = 19.97; interleukin-1 receptor-associated kinase 3" ID="ID_663930218" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K14: 1.47-fold Down; FDR = 0.00704; PValue = 0.00157; mean CPM = 9.470; mitogen-activated protein kinase kinase kinase 14" ID="ID_1832139145" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K3: 1.26-fold Down; FDR = 0.00786; PValue = 0.00178; mean CPM = 38.85; mitogen-activated protein kinase kinase kinase 3" ID="ID_1053937153" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCZ: 1.51-fold Up; FDR = 0.0152; PValue = 0.00381; mean CPM = 10.46; protein kinase C, zeta" ID="ID_1600344318" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PELI2: 1.41-fold Down; FDR = 0.0196; PValue = 0.00515; mean CPM = 6.598; pellino homolog 2 (Drosophila)" ID="ID_430841687" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_240551753" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_494981103" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ECSIT: 1.2-fold Down; FDR = 0.0358; PValue = 0.0104; mean CPM = 54.27; ECSIT homolog (Drosophila)" ID="ID_1638413501" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_254688458" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1RAP: 1.35-fold Up; FDR = 0.0392; PValue = 0.0116; mean CPM = 10.66; interleukin 1 receptor accessory protein" ID="ID_963344771" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_70838234" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_1988551417" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_128567325" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK2: 1.27-fold Down; FDR = 0.259; PValue = 0.113; mean CPM = 10.13; interleukin-1 receptor-associated kinase 2" ID="ID_1706148582" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SQSTM1: 1.19-fold Down; FDR = 0.289; PValue = 0.129; mean CPM = 270.1; sequestosome 1" ID="ID_1028942611" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1A: 1.5-fold Up; FDR = 0.315; PValue = 0.144; mean CPM = 155.4; interleukin 1, alpha" ID="ID_213694035" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP1: 1.12-fold Down; FDR = 0.351; PValue = 0.165; mean CPM = 17.96; TGF-beta activated kinase 1/MAP3K7 binding protein 1" ID="ID_1914443593" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_807667045" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1755426014" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_382778072" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="UBE2V1: 1.11-fold Down; FDR = 0.482; PValue = 0.246; mean CPM = 13.47; ubiquitin-conjugating enzyme E2 variant 1" ID="ID_620924038" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000038917: 1.08-fold Up; FDR = 0.591; PValue = 0.323; mean CPM = 33.13; Uncharacterized protein" ID="ID_118192700" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_632905470" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPKAPK2: 1.06-fold Down; FDR = 0.733; PValue = 0.435; mean CPM = 82.16; mitogen-activated protein kinase-activated protein kinase 2" ID="ID_485135048" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1205369164" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_10090121" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK1: 1.04-fold Down; FDR = 0.885; PValue = 0.606; mean CPM = 41.54; interleukin-1 receptor-associated kinase 1" ID="ID_945120311" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K2: 1.03-fold Up; FDR = 0.924; PValue = 0.73; mean CPM = 40.64; mitogen-activated protein kinase kinase kinase 2" ID="ID_90017112" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_762066064" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_797492117" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPB2: 1.05-fold Down; FDR = 1; PValue = 0.889; mean CPM = 0.9668; heat shock 27kDa protein 2" ID="ID_136293897" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_97607242" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-8: FDR = 3.83e-05, PValue = 3.12e-05" ID="ID_1696703315" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_1169682690" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_756151450" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPG2: 2.83-fold Down; FDR = 8.45e-10; PValue = 2.83e-11; mean CPM = 1670; heparan sulfate proteoglycan 2" ID="ID_1737520425" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR4: 3.45-fold Up; FDR = 3.1e-09; PValue = 1.19e-10; mean CPM = 7.456; Macaca mulatta toll-like receptor 4 (TLR4), mRNA." ID="ID_1747155028" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGFR: 1.84-fold Up; FDR = 6.71e-09; PValue = 2.77e-10; mean CPM = 68.58; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)" ID="ID_628645776" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1877330609" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_387075614" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_283344102" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL10: 1.55-fold Up; FDR = 5.92e-06; PValue = 5.22e-07; mean CPM = 21.83; B-cell CLL/lymphoma 10" ID="ID_1110404747" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOD1: 1.63-fold Up; FDR = 0.000193; PValue = 2.61e-05; mean CPM = 58.36; nucleotide-binding oligomerization domain containing 1" ID="ID_1196077022" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AR: 2.06-fold Up; FDR = 0.000527; PValue = 8.13e-05; mean CPM = 4.804; Macaca mulatta androgen receptor (AR), mRNA." ID="ID_1000584818" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTOR: 1.3-fold Down; FDR = 0.00117; PValue = 0.000201; mean CPM = 107.5; mechanistic target of rapamycin (serine/threonine kinase)" ID="ID_1203590364" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRRT2: 3.34-fold Down; FDR = 0.00175; PValue = 0.000318; mean CPM = 1.259; proline-rich transmembrane protein 2" ID="ID_1556600277" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APOE: 1.75-fold Down; FDR = 0.0148; PValue = 0.00369; mean CPM = 24.21; apolipoprotein E" ID="ID_621798072" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_905223841" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL8: 2.33-fold Up; FDR = 0.0209; PValue = 0.00552; mean CPM = 2326; interleukin 8" ID="ID_202657696" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_131192459" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KDR: 2.01-fold Up; FDR = 0.0328; PValue = 0.00936; mean CPM = 2.053; kinase insert domain receptor (a type III receptor tyrosine kinase)" ID="ID_1816778046" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1525855255" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL3: 1.25-fold Up; FDR = 0.0559; PValue = 0.0175; mean CPM = 16.96; B-cell CLL/lymphoma 3" ID="ID_1828452451" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1122864215" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_1054295391" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTTN: 1.12-fold Down; FDR = 0.304; PValue = 0.138; mean CPM = 500.4; cortactin" ID="ID_1565629578" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_545535854" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_532466002" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2: 1.1-fold Up; FDR = 0.394; PValue = 0.191; mean CPM = 102.5; PTK2 protein tyrosine kinase 2" ID="ID_732437398" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1729449203" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACTR2: 1.09-fold Up; FDR = 0.44; PValue = 0.219; mean CPM = 263.8; ARP2 actin-related protein 2 homolog (yeast)" ID="ID_675083928" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_147228307" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR7: 1.37-fold Down; FDR = 0.878; PValue = 0.597; mean CPM = 0.8402; toll-like receptor 7" ID="ID_535318956" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACTR3: 1.13-fold Up; FDR = 0.908; PValue = 0.681; mean CPM = 0.7943; ARP3 actin-related protein 3 homolog (yeast)" ID="ID_1258329642" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALCA: 1.22-fold Up; FDR = 0.928; PValue = 0.736; mean CPM = 0.8122; calcitonin-related polypeptide alpha" ID="ID_1502763728" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17F: 1.11-fold Down; FDR = 0.948; PValue = 0.771; mean CPM = 1.150; interleukin 17F" ID="ID_1527550809" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APOA2: 1.13-fold Down; FDR = 0.993; PValue = 0.847; mean CPM = 0.8139; apolipoprotein A-II" ID="ID_768820129" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCR2: 1.14-fold Up; FDR = 1; PValue = 0.929; mean CPM = 0.8384; chemokine (C-X-C motif) receptor 2" ID="ID_328311069" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRG3: No Change; FDR = 1; PValue = 1; mean CPM = 0.7866; proteoglycan 3" ID="ID_1751237850" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCR1: No Change; FDR = 1; PValue = 1; mean CPM = 0.7827; chemokine (C-X-C motif) receptor 1" ID="ID_1177865425" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Vitamin D: FDR = 0.000311, PValue = 0.000259" ID="ID_546827429" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="HDAC5: 1.72-fold Down; FDR = 2.07e-09; PValue = 7.53e-11; mean CPM = 122.7; histone deacetylase 5" ID="ID_64468140" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MEF2D: 1.73-fold Down; FDR = 2.02e-08; PValue = 9.5e-10; mean CPM = 61.43; myocyte enhancer factor 2D" ID="ID_1119415063" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMARCAL1: 1.57-fold Up; FDR = 2.55e-08; PValue = 1.23e-09; mean CPM = 35.29; Uncharacterized protein" ID="ID_1803334209" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC9: 4.18-fold Down; FDR = 2.74e-08; PValue = 1.34e-09; mean CPM = 25.34; histone deacetylase 9" ID="ID_1367949093" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMARCA5: 1.51-fold Up; FDR = 1.43e-07; PValue = 8.31e-09; mean CPM = 184.6; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5" ID="ID_557022844" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMARCA4: 1.49-fold Down; FDR = 3.19e-07; PValue = 2.01e-08; mean CPM = 157.3; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4" ID="ID_535526239" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_192511891" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_83279191" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMARCD3: 1.5-fold Down; FDR = 6.15e-06; PValue = 5.46e-07; mean CPM = 36.08; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3" ID="ID_889253029" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1000802144" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC7: 1.43-fold Down; FDR = 5.36e-05; PValue = 6.14e-06; mean CPM = 25.32; Uncharacterized protein" ID="ID_266932918" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPP1: 2.25-fold Down; FDR = 7.74e-05; PValue = 9.29e-06; mean CPM = 35.33; secreted phosphoprotein 1" ID="ID_1248246101" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCE: 1.73-fold Up; FDR = 0.00013; PValue = 1.67e-05; mean CPM = 10.87; protein kinase C, epsilon" ID="ID_308474114" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACA: 1.36-fold Down; FDR = 0.000167; PValue = 2.22e-05; mean CPM = 37.75; protein kinase, cAMP-dependent, catalytic, alpha" ID="ID_1484093915" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000028518: 1.35-fold Down; FDR = 0.000199; PValue = 2.72e-05; mean CPM = 42.49" ID="ID_1423867456" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLTF: 1.37-fold Up; FDR = 0.000275; PValue = 3.91e-05; mean CPM = 48.37; helicase-like transcription factor" ID="ID_984660681" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SIN3A: 1.33-fold Up; FDR = 0.000459; PValue = 6.96e-05; mean CPM = 56.62; SIN3 homolog A, transcription regulator (yeast)" ID="ID_1838073647" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMARCC1: 1.31-fold Down; FDR = 0.000832; PValue = 0.000136; mean CPM = 55.44; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1" ID="ID_1399055462" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000039874: 1.3-fold Up; FDR = 0.001; PValue = 0.000168; mean CPM = 80.13; Uncharacterized protein" ID="ID_1312424165" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCH: 1.98-fold Down; FDR = 0.00105; PValue = 0.000179; mean CPM = 3.182; protein kinase C, eta" ID="ID_1378919153" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000031974: 1.38-fold Down; FDR = 0.00112; PValue = 0.000192; mean CPM = 16.65; Uncharacterized protein" ID="ID_1780734567" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMARCD1: 1.31-fold Up; FDR = 0.00181; PValue = 0.000332; mean CPM = 31.72; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1" ID="ID_501773624" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GTF2B: 1.3-fold Up; FDR = 0.0019; PValue = 0.000351; mean CPM = 38.87; general transcription factor IIB" ID="ID_722046523" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKD3: 1.29-fold Up; FDR = 0.00214; PValue = 0.0004; mean CPM = 43.43; protein kinase D3" ID="ID_1553505790" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG1: 1.31-fold Down; FDR = 0.00352; PValue = 0.000707; mean CPM = 53.66; phospholipase C, gamma 1" ID="ID_520748344" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAZ1B: 1.27-fold Up; FDR = 0.00357; PValue = 0.00072; mean CPM = 170.6; bromodomain adjacent to zinc finger domain, 1B" ID="ID_164033913" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC4: 1.38-fold Down; FDR = 0.00526; PValue = 0.00112; mean CPM = 48.60; histone deacetylase 4" ID="ID_798159684" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHAF1A: 1.42-fold Down; FDR = 0.0138; PValue = 0.00339; mean CPM = 19.62; Uncharacterized protein" ID="ID_1882251508" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCZ: 1.51-fold Up; FDR = 0.0152; PValue = 0.00381; mean CPM = 10.46; protein kinase C, zeta" ID="ID_536256523" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC1: 1.25-fold Up; FDR = 0.0159; PValue = 0.00403; mean CPM = 27.51; histone deacetylase 1" ID="ID_727476417" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1429696553" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SUPT16H: 1.21-fold Up; FDR = 0.0239; PValue = 0.00646; mean CPM = 153.4; suppressor of Ty 16 homolog (S. cerevisiae)" ID="ID_745092065" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB1: 1.21-fold Up; FDR = 0.0313; PValue = 0.00884; mean CPM = 36.07; cAMP responsive element binding protein 1" ID="ID_1893260965" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC6: 1.21-fold Down; FDR = 0.0436; PValue = 0.0131; mean CPM = 30.86; histone deacetylase 6" ID="ID_1290788324" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYP2R1: 1.51-fold Up; FDR = 0.0616; PValue = 0.0197; mean CPM = 3.294; cytochrome P450, family 2, subfamily R, polypeptide 1" ID="ID_687601474" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RXRA: 1.18-fold Down; FDR = 0.077; PValue = 0.0257; mean CPM = 35.60; retinoid X receptor, alpha" ID="ID_1107604090" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACTL6A: 1.18-fold Up; FDR = 0.099; PValue = 0.0346; mean CPM = 28.90; actin-like 6A" ID="ID_223872905" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC2: 1.15-fold Up; FDR = 0.115; PValue = 0.0414; mean CPM = 93.64; histone deacetylase 2" ID="ID_1986014345" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KDM1A: 1.14-fold Down; FDR = 0.177; PValue = 0.0705; mean CPM = 77.01; lysine (K)-specific demethylase 1A" ID="ID_61079771" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASGRP1: 1.4-fold Down; FDR = 0.224; PValue = 0.0945; mean CPM = 2.348; RAS guanyl releasing protein 1 (calcium and DAG-regulated)" ID="ID_1654133271" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1A: 1.16-fold Down; FDR = 0.28; PValue = 0.124; mean CPM = 363.2; Cyclin-dependent kinase inhibitor 1; Uncharacterized protein" ID="ID_1069085157" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EP300: 1.11-fold Up; FDR = 0.312; PValue = 0.142; mean CPM = 162.8; E1A binding protein p300" ID="ID_665431336" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_875080763" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYP24A1: 1.82-fold Down; FDR = 0.34; PValue = 0.158; mean CPM = 1.131; cytochrome P450, family 24, subfamily A, polypeptide 1" ID="ID_1212884996" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MEF2C: 1.24-fold Down; FDR = 0.357; PValue = 0.168; mean CPM = 6.816; myocyte enhancer factor 2C" ID="ID_157201945" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMARCC2: 1.1-fold Down; FDR = 0.371; PValue = 0.176; mean CPM = 86.26; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2" ID="ID_1351649171" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1585271930" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1287664840" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC10: 1.1-fold Down; FDR = 0.489; PValue = 0.251; mean CPM = 21.21; Uncharacterized protein" ID="ID_1515310375" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCI: 1.08-fold Up; FDR = 0.518; PValue = 0.271; mean CPM = 47.99; protein kinase C, iota" ID="ID_502787380" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCQ: 1.56-fold Up; FDR = 0.522; PValue = 0.274; mean CPM = 1.047; Uncharacterized protein" ID="ID_1997955845" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_158605201" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCG: 1.47-fold Down; FDR = 0.609; PValue = 0.336; mean CPM = 0.9297; protein kinase C, gamma" ID="ID_1427377554" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMARCA2: 1.07-fold Down; FDR = 0.654; PValue = 0.37; mean CPM = 65.89; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2" ID="ID_493889631" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCD: 1.06-fold Up; FDR = 0.696; PValue = 0.404; mean CPM = 37.45; protein kinase C, delta" ID="ID_776445396" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCB: 1.86-fold Up; FDR = 0.727; PValue = 0.43; mean CPM = 0.8705; protein kinase C, beta" ID="ID_1839951248" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC8: 1.06-fold Up; FDR = 0.76; PValue = 0.459; mean CPM = 20.83; histone deacetylase 8" ID="ID_841291410" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GC: 1.53-fold Up; FDR = 0.789; PValue = 0.486; mean CPM = 0.8281; Uncharacterized protein" ID="ID_569668438" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACG: 1.51-fold Down; FDR = 0.795; PValue = 0.491; mean CPM = 0.8026; protein kinase, cAMP-dependent, catalytic, gamma" ID="ID_78596718" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYP27B1: 1.09-fold Up; FDR = 0.856; PValue = 0.569; mean CPM = 3.584; cytochrome P450, family 27, subfamily B, polypeptide 1" ID="ID_722625607" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_139100145" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACTL6B: 1.43-fold Down; FDR = 0.9; PValue = 0.636; mean CPM = 0.8538; actin-like 6B" ID="ID_245183519" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARID1B: 1.04-fold Down; FDR = 0.908; PValue = 0.683; mean CPM = 80.39; AT rich interactive domain 1B (SWI1-like)" ID="ID_1710081712" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMARCA1: 1.04-fold Down; FDR = 0.908; PValue = 0.683; mean CPM = 122.1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1" ID="ID_1922362757" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACB: 1.03-fold Up; FDR = 0.911; PValue = 0.694; mean CPM = 30.10; protein kinase, cAMP-dependent, catalytic, beta" ID="ID_1455481713" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MED1: 1.03-fold Up; FDR = 0.911; PValue = 0.699; mean CPM = 81.93; mediator complex subunit 1" ID="ID_1314849405" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RXRG: 1.32-fold Up; FDR = 0.915; PValue = 0.714; mean CPM = 0.8688; retinoid X receptor, gamma" ID="ID_132685898" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG2: 1.06-fold Up; FDR = 0.985; PValue = 0.834; mean CPM = 2.248; phospholipase C, gamma 2 (phosphatidylinositol-specific)" ID="ID_1701785800" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREBBP: 1.01-fold Down; FDR = 0.993; PValue = 0.847; mean CPM = 137.7; CREB binding protein" ID="ID_1367775972" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALB1: 1.07-fold Down; FDR = 0.994; PValue = 0.849; mean CPM = 1.025; calbindin 1, 28kDa" ID="ID_269397883" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC3: 1.01-fold Up; FDR = 1; PValue = 0.861; mean CPM = 41.13; histone deacetylase 3" ID="ID_1075385752" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMARCE1: No Change; FDR = 1; PValue = 0.982; mean CPM = 71.75; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1" ID="ID_434263788" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMARCD2: No Change; FDR = 1; PValue = 1; mean CPM = 35.43; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2" ID="ID_1956406032" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTH: No Change; FDR = 1; PValue = 1; mean CPM = 0.7843; parathyroid hormone" ID="ID_163983629" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-2 : FDR = 0.000438, PValue = 0.000375" ID="ID_1030859166" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="STAT5A: 2.28-fold Up; FDR = 6.87e-14; PValue = 8.58e-16; mean CPM = 21.55; signal transducer and activator of transcription 5A" ID="ID_1587515457" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_1960901091" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2B: 3.54-fold Up; FDR = 1.24e-07; PValue = 7.07e-09; mean CPM = 5.971; PTK2B protein tyrosine kinase 2 beta" ID="ID_374506345" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_893299281" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_261672544" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_1837144474" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1027405123" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_1426900855" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1088982623" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK3: 2.31-fold Up; FDR = 0.00186; PValue = 0.000342; mean CPM = 2.154; Janus kinase 3" ID="ID_1184615614" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1S1: 1.31-fold Down; FDR = 0.00202; PValue = 0.000375; mean CPM = 35.32; AKT1 substrate 1 (proline-rich)" ID="ID_1972200123" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLEKHO1: 1.3-fold Down; FDR = 0.00647; PValue = 0.00142; mean CPM = 47.00; pleckstrin homology domain containing, family O member 1" ID="ID_799729365" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSNK2A2: 1.28-fold Up; FDR = 0.0129; PValue = 0.00314; mean CPM = 19.86; casein kinase 2, alpha prime polypeptide" ID="ID_1162805683" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_683883196" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1980393936" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_1662038271" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_1635299228" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS2: 1.17-fold Up; FDR = 0.1; PValue = 0.0353; mean CPM = 31.79; son of sevenless homolog 2 (Drosophila)" ID="ID_13082117" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_255836892" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1842185005" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_146258516" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_1807181488" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_1471460078" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_544748815" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3C2B: 1.17-fold Down; FDR = 0.406; PValue = 0.198; mean CPM = 6.381; phosphoinositide-3-kinase, class 2, beta polypeptide" ID="ID_727759948" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1796326678" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_92305250" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_1207783879" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1364895803" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2RA: 1.08-fold Up; FDR = 0.945; PValue = 0.766; mean CPM = 0.8493; interleukin 2 receptor, alpha" ID="ID_1220227155" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_1787197551" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSNK2B: 1.02-fold Down; FDR = 0.956; PValue = 0.787; mean CPM = 77.24; Casein kinase II subunit beta (CK II beta)(Phosvitin)(Protein G5a)" ID="ID_59307913" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3C2A: 1.02-fold Up; FDR = 0.957; PValue = 0.788; mean CPM = 84.41; phosphoinositide-3-kinase, class 2, alpha polypeptide" ID="ID_1461835517" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SYK: 1.11-fold Up; FDR = 1; PValue = 0.977; mean CPM = 0.8420; spleen tyrosine kinase" ID="ID_964154477" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2: 1.03-fold Up; FDR = 1; PValue = 0.998; mean CPM = 0.7974; interleukin 2" ID="ID_1550675512" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="RXR: FDR = 0.000438, PValue = 0.000381" ID="ID_1328234594" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="NCOA2: 1.84-fold Up; FDR = 6.82e-14; PValue = 8.49e-16; mean CPM = 56.22; nuclear receptor coactivator 2" ID="ID_764107468" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GTF2E1: 1.41-fold Up; FDR = 0.000355; PValue = 5.22e-05; mean CPM = 29.08; general transcription factor IIE, polypeptide 1, alpha 56kDa" ID="ID_1001951759" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GTF2B: 1.3-fold Up; FDR = 0.0019; PValue = 0.000351; mean CPM = 38.87; general transcription factor IIB" ID="ID_248426050" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GTF2A1: 1.27-fold Up; FDR = 0.00826; PValue = 0.00188; mean CPM = 30.38; general transcription factor IIA, 1, 19/37kDa" ID="ID_1689449033" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCOA3: 1.24-fold Up; FDR = 0.0123; PValue = 0.00297; mean CPM = 178.3; nuclear receptor coactivator 3" ID="ID_574824836" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GTF2F1: 1.32-fold Down; FDR = 0.0374; PValue = 0.0109; mean CPM = 8.075; general transcription factor IIF, polypeptide 1, 74kDa" ID="ID_972572983" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RXRA: 1.18-fold Down; FDR = 0.077; PValue = 0.0257; mean CPM = 35.60; retinoid X receptor, alpha" ID="ID_1089990641" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCOA1: 1.18-fold Up; FDR = 0.112; PValue = 0.04; mean CPM = 20.42; nuclear receptor coactivator 1" ID="ID_1787281761" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="POLR2A: 1.12-fold Down; FDR = 0.365; PValue = 0.172; mean CPM = 296.4; polymerase (RNA) II (DNA directed) polypeptide A, 220kDa" ID="ID_677984839" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBP: 1.12-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 14.69; TATA box binding protein" ID="ID_910601404" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KAT2B: 1.13-fold Up; FDR = 0.663; PValue = 0.378; mean CPM = 11.06; Uncharacterized protein" ID="ID_1708319003" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ERCC3: 1.05-fold Down; FDR = 0.746; PValue = 0.446; mean CPM = 82.81; Uncharacterized protein" ID="ID_185191599" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC3: 1.01-fold Up; FDR = 1; PValue = 0.861; mean CPM = 41.13; histone deacetylase 3" ID="ID_352991986" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="MAPK: FDR = 0.000643, PValue = 0.000571" ID="ID_171468749" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_223891410" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MRAS: 2.04-fold Up; FDR = 4.47e-15; PValue = 4.43e-17; mean CPM = 41.38; muscle RAS oncogene homolog" ID="ID_36866449" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB3: 4.82-fold Down; FDR = 1.82e-12; PValue = 3.09e-14; mean CPM = 9.911; transforming growth factor, beta 3" ID="ID_1836433100" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SRF: 1.69-fold Down; FDR = 8.07e-11; PValue = 2.06e-12; mean CPM = 34.61; serum response factor (c-fos serum response element-binding transcription factor)" ID="ID_1674381414" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA1B: 2.24-fold Down; FDR = 4.33e-09; PValue = 1.71e-10; mean CPM = 44.90; Heat shock 70 kDa protein 1A/1B (Heat shock 70 kDa protein 1/2)(HSP70.1/HSP70.2)(HSP70-1/HSP70-2)" ID="ID_1712379152" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGFR: 1.84-fold Up; FDR = 6.71e-09; PValue = 2.77e-10; mean CPM = 68.58; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)" ID="ID_1668159629" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGFR2: 3.45-fold Down; FDR = 1.04e-08; PValue = 4.53e-10; mean CPM = 5.064; fibroblast growth factor receptor 2" ID="ID_1376612917" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA8: 1.64-fold Up; FDR = 1.46e-08; PValue = 6.6e-10; mean CPM = 1881; heat shock 70kDa protein 8" ID="ID_1919414455" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FLNA: 2.35-fold Down; FDR = 2.01e-08; PValue = 9.45e-10; mean CPM = 7159; filamin A, alpha" ID="ID_856709048" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DUSP7: 1.77-fold Down; FDR = 3.08e-08; PValue = 1.52e-09; mean CPM = 22.67; dual specificity phosphatase 7" ID="ID_1696001105" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TAOK2: 1.59-fold Down; FDR = 9.28e-08; PValue = 5.13e-09; mean CPM = 76.85; TAO kinase 2" ID="ID_1871500637" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1B: 1.55-fold Up; FDR = 2.39e-07; PValue = 1.46e-08; mean CPM = 135.3; Ras-related protein Rap-1b; Ras-related protein Rap-1b isoform 1; Uncharacterized protein" ID="ID_285611133" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K6: 2.05-fold Down; FDR = 2.49e-07; PValue = 1.53e-08; mean CPM = 17.57; Uncharacterized protein" ID="ID_874460960" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_206400078" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD14: 2.75-fold Down; FDR = 6.54e-07; PValue = 4.46e-08; mean CPM = 5.195; CD14 molecule" ID="ID_254084099" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DDIT3: 2.05-fold Up; FDR = 1.46e-06; PValue = 1.09e-07; mean CPM = 45.52; DNA-damage-inducible transcript 3" ID="ID_908252128" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_331945495" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_180111679" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DUSP5: 1.66-fold Up; FDR = 2.33e-06; PValue = 1.84e-07; mean CPM = 66.43; dual specificity phosphatase 5" ID="ID_897554319" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGFR3: 3.85-fold Down; FDR = 2.66e-06; PValue = 2.13e-07; mean CPM = 2.800; fibroblast growth factor receptor 3" ID="ID_1051928871" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K3: 1.45-fold Down; FDR = 7.01e-06; PValue = 6.34e-07; mean CPM = 180.1; mitogen-activated protein kinase kinase 3" ID="ID_290041197" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MINK1: 1.41-fold Down; FDR = 9.48e-06; PValue = 8.88e-07; mean CPM = 87.29; misshapen-like kinase 1" ID="ID_136293858" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8IP3: 1.77-fold Down; FDR = 1.28e-05; PValue = 1.24e-06; mean CPM = 65.23; mitogen-activated protein kinase 8 interacting protein 3" ID="ID_1964455402" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA5: 3.28-fold Up; FDR = 1.4e-05; PValue = 1.36e-06; mean CPM = 2.288; ribosomal protein S6 kinase, 90kDa, polypeptide 5" ID="ID_1261066120" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_372500315" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASGRF2: 5.55-fold Up; FDR = 2.4e-05; PValue = 2.48e-06; mean CPM = 2.163; Ras protein-specific guanine nucleotide-releasing factor 2" ID="ID_784667420" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP4K4: 1.4-fold Down; FDR = 3.08e-05; PValue = 3.27e-06; mean CPM = 242.8; mitogen-activated protein kinase kinase kinase kinase 4" ID="ID_647230457" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPT: 2.89-fold Down; FDR = 3.14e-05; PValue = 3.34e-06; mean CPM = 2.105; microtubule-associated protein tau" ID="ID_1405187357" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1R1: 1.6-fold Up; FDR = 3.35e-05; PValue = 3.61e-06; mean CPM = 123.7; interleukin 1 receptor, type I" ID="ID_636422032" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K5: 1.55-fold Up; FDR = 7.6e-05; PValue = 9.12e-06; mean CPM = 16.82; mitogen-activated protein kinase kinase 5" ID="ID_721834554" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACA: 1.36-fold Down; FDR = 0.000167; PValue = 2.22e-05; mean CPM = 37.75; protein kinase, cAMP-dependent, catalytic, alpha" ID="ID_309405111" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP2: 1.45-fold Up; FDR = 0.000179; PValue = 2.4e-05; mean CPM = 65.31; TGF-beta activated kinase 1/MAP3K7 binding protein 2" ID="ID_1090544120" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP3CA: 1.55-fold Up; FDR = 0.0003; PValue = 4.32e-05; mean CPM = 40.21; protein phosphatase 3, catalytic subunit, alpha isozyme" ID="ID_1050282457" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF2: 1.34-fold Up; FDR = 0.000403; PValue = 6.01e-05; mean CPM = 39.83; activating transcription factor 2" ID="ID_1675472210" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_397530605" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNA12: 1.32-fold Down; FDR = 0.000955; PValue = 0.00016; mean CPM = 33.75; Uncharacterized protein" ID="ID_899538509" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPM1A: 1.31-fold Up; FDR = 0.00101; PValue = 0.00017; mean CPM = 60.08; protein phosphatase, Mg2+/Mn2+ dependent, 1A" ID="ID_1937637739" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCH: 1.98-fold Down; FDR = 0.00105; PValue = 0.000179; mean CPM = 3.182; protein kinase C, eta" ID="ID_57466312" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NR4A1: 1.74-fold Down; FDR = 0.00108; PValue = 0.000184; mean CPM = 312.6; nuclear receptor subfamily 4, group A, member 1" ID="ID_1078116241" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DUSP1: 1.39-fold Down; FDR = 0.00173; PValue = 0.000315; mean CPM = 355.2; dual specificity phosphatase 1" ID="ID_758485454" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPM1B: 1.36-fold Up; FDR = 0.00193; PValue = 0.000358; mean CPM = 16.96; protein phosphatase, Mg2+/Mn2+ dependent, 1B" ID="ID_1723523792" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NGF: 1.32-fold Up; FDR = 0.00212; PValue = 0.000396; mean CPM = 198.5; nerve growth factor (beta polypeptide)" ID="ID_313477356" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF4: 1.29-fold Up; FDR = 0.00296; PValue = 0.000579; mean CPM = 618.7; activating transcription factor 4 (tax-responsive enhancer element B67)" ID="ID_679232185" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DUSP10: 1.56-fold Down; FDR = 0.00343; PValue = 0.000687; mean CPM = 9.531; dual specificity phosphatase 10" ID="ID_1932391956" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1B: 1.43-fold Up; FDR = 0.00346; PValue = 0.000693; mean CPM = 12.81; RAP1B, member of RAS oncogene family" ID="ID_1994834540" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAX: 1.28-fold Up; FDR = 0.00569; PValue = 0.00123; mean CPM = 29.78; MYC associated factor X" ID="ID_1269800129" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_1772384058" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K14: 1.47-fold Down; FDR = 0.00704; PValue = 0.00157; mean CPM = 9.470; mitogen-activated protein kinase kinase kinase 14" ID="ID_596981305" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K3: 1.26-fold Down; FDR = 0.00786; PValue = 0.00178; mean CPM = 38.85; mitogen-activated protein kinase kinase kinase 3" ID="ID_1150169515" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K11: 1.24-fold Down; FDR = 0.0116; PValue = 0.00279; mean CPM = 45.82; mitogen-activated protein kinase kinase kinase 11" ID="ID_328939225" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFB: 1.97-fold Down; FDR = 0.0133; PValue = 0.00326; mean CPM = 2.424; platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)" ID="ID_1459150561" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCZ: 1.51-fold Up; FDR = 0.0152; PValue = 0.00381; mean CPM = 10.46; protein kinase C, zeta" ID="ID_998573258" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BDNF: 1.23-fold Down; FDR = 0.0158; PValue = 0.00399; mean CPM = 104.4; Brain-derived neurotrophic factor" ID="ID_101832539" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN5: 3.05-fold Down; FDR = 0.0177; PValue = 0.00455; mean CPM = 1.043; protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)" ID="ID_726251853" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_608177977" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_258042686" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_371907432" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC2: 2.96-fold Up; FDR = 0.0309; PValue = 0.00872; mean CPM = 0.9737; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)" ID="ID_665944474" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GADD45A: 1.22-fold Up; FDR = 0.0344; PValue = 0.00989; mean CPM = 127.8; growth arrest and DNA-damage-inducible, alpha" ID="ID_636478660" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ECSIT: 1.2-fold Down; FDR = 0.0358; PValue = 0.0104; mean CPM = 54.27; ECSIT homolog (Drosophila)" ID="ID_443322384" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFBR1: 1.2-fold Up; FDR = 0.037; PValue = 0.0108; mean CPM = 90.92; transforming growth factor, beta receptor 1" ID="ID_1490402432" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1942410723" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KRAS: 1.35-fold Down; FDR = 0.0401; PValue = 0.0119; mean CPM = 13.10; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog" ID="ID_1955413254" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NRAS: 1.2-fold Down; FDR = 0.0546; PValue = 0.017; mean CPM = 32.39; neuroblastoma RAS viral (v-ras) oncogene homolog" ID="ID_1585254984" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPRR: 1.72-fold Down; FDR = 0.0559; PValue = 0.0175; mean CPM = 7.682; protein tyrosine phosphatase, receptor type, R" ID="ID_347207566" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFBR2: 1.19-fold Up; FDR = 0.0643; PValue = 0.0208; mean CPM = 350.8; transforming growth factor, beta receptor II (70/80kDa)" ID="ID_1589401575" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_1897843161" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MKNK1: 1.27-fold Down; FDR = 0.0706; PValue = 0.0232; mean CPM = 9.169; MAP kinase interacting serine/threonine kinase 1" ID="ID_390503137" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TAOK1: 1.17-fold Up; FDR = 0.0749; PValue = 0.0249; mean CPM = 101.1; TAO kinase 1" ID="ID_1651870875" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K8: 1.35-fold Down; FDR = 0.0831; PValue = 0.0281; mean CPM = 8.912; mitogen-activated protein kinase kinase kinase 8" ID="ID_396376171" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1A: 1.17-fold Up; FDR = 0.0888; PValue = 0.0304; mean CPM = 37.16; RAP1A, member of RAS oncogene family" ID="ID_433755471" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS2: 1.17-fold Up; FDR = 0.1; PValue = 0.0353; mean CPM = 31.79; son of sevenless homolog 2 (Drosophila)" ID="ID_868278128" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARRB1: 1.35-fold Down; FDR = 0.107; PValue = 0.0382; mean CPM = 4.106; arrestin, beta 1" ID="ID_1620771078" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_1507806278" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MKNK2: 1.23-fold Up; FDR = 0.123; PValue = 0.0449; mean CPM = 81.36; MAP kinase interacting serine/threonine kinase 2" ID="ID_250107508" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_1902955291" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DUSP6: 1.22-fold Up; FDR = 0.131; PValue = 0.0487; mean CPM = 91.01; dual specificity phosphatase 6" ID="ID_488675160" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK2: 1.15-fold Up; FDR = 0.134; PValue = 0.0502; mean CPM = 89.49; p21 protein (Cdc42/Rac)-activated kinase 2" ID="ID_410756608" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGFR1: 1.15-fold Down; FDR = 0.139; PValue = 0.0525; mean CPM = 89.41; fibroblast growth factor receptor 1" ID="ID_272200243" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1537543828" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD1: 1.23-fold Down; FDR = 0.154; PValue = 0.0592; mean CPM = 31.65; frizzled homolog 1 (Drosophila)" ID="ID_226930778" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP6: 1.17-fold Up; FDR = 0.197; PValue = 0.0807; mean CPM = 14.25; caspase 6, apoptosis-related cysteine peptidase" ID="ID_561523870" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_352539056" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DUSP4: 1.28-fold Down; FDR = 0.199; PValue = 0.0817; mean CPM = 66.70; dual specificity phosphatase 4" ID="ID_988060644" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP7: 1.15-fold Up; FDR = 0.218; PValue = 0.0916; mean CPM = 21.49; caspase 7, apoptosis-related cysteine peptidase" ID="ID_209682623" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASGRP1: 1.4-fold Down; FDR = 0.224; PValue = 0.0945; mean CPM = 2.348; RAS guanyl releasing protein 1 (calcium and DAG-regulated)" ID="ID_1702462219" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BRAF: 1.14-fold Down; FDR = 0.228; PValue = 0.0964; mean CPM = 24.98; v-raf murine sarcoma viral oncogene homolog B1" ID="ID_606904284" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_1793090771" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K4: 1.13-fold Down; FDR = 0.284; PValue = 0.126; mean CPM = 25.34; Uncharacterized protein" ID="ID_1016546905" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA4: 1.12-fold Down; FDR = 0.296; PValue = 0.133; mean CPM = 39.50; ribosomal protein S6 kinase, 90kDa, polypeptide 4" ID="ID_1151197757" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPKAPK5: 1.15-fold Down; FDR = 0.297; PValue = 0.134; mean CPM = 13.06; mitogen-activated protein kinase-activated protein kinase 5" ID="ID_1483352601" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1A: 1.5-fold Up; FDR = 0.315; PValue = 0.144; mean CPM = 155.4; interleukin 1, alpha" ID="ID_1774344017" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP1: 1.12-fold Down; FDR = 0.351; PValue = 0.165; mean CPM = 17.96; TGF-beta activated kinase 1/MAP3K7 binding protein 1" ID="ID_940024168" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MEF2C: 1.24-fold Down; FDR = 0.357; PValue = 0.168; mean CPM = 6.816; myocyte enhancer factor 2C" ID="ID_726841070" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP53: 1.11-fold Down; FDR = 0.364; PValue = 0.172; mean CPM = 33.25; tumor protein p53" ID="ID_477560311" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRKL: 1.11-fold Up; FDR = 0.371; PValue = 0.176; mean CPM = 34.10; v-crk sarcoma virus CT10 oncogene homolog (avian)-like" ID="ID_1006176039" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NF1: 1.1-fold Up; FDR = 0.383; PValue = 0.184; mean CPM = 199.1; neurofibromin 1" ID="ID_845032484" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK6: 1.34-fold Up; FDR = 0.407; PValue = 0.198; mean CPM = 2.043; mitogen-activated protein kinase 6" ID="ID_1676927294" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1095482911" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK12: 1.19-fold Down; FDR = 0.422; PValue = 0.208; mean CPM = 6.569; mitogen-activated protein kinase 12" ID="ID_1263846742" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1668197528" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC1: 1.11-fold Down; FDR = 0.457; PValue = 0.23; mean CPM = 19.06; Uncharacterized protein" ID="ID_689943714" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP3CB: 1.08-fold Up; FDR = 0.514; PValue = 0.268; mean CPM = 76.44; protein phosphatase 3, catalytic subunit, beta isozyme" ID="ID_1440361036" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK13: 1.22-fold Down; FDR = 0.536; PValue = 0.284; mean CPM = 3.100; mitogen-activated protein kinase 13" ID="ID_1277131449" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACVR1C: 1.28-fold Down; FDR = 0.559; PValue = 0.3; mean CPM = 1.935; activin A receptor, type IC" ID="ID_1441799876" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K5: 1.21-fold Down; FDR = 0.6; PValue = 0.33; mean CPM = 8.023; mitogen-activated protein kinase kinase kinase 5" ID="ID_69328456" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDC42: 1.07-fold Down; FDR = 0.608; PValue = 0.335; mean CPM = 91.67; cell division cycle 42" ID="ID_1314216051" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCG: 1.47-fold Down; FDR = 0.609; PValue = 0.336; mean CPM = 0.9297; protein kinase C, gamma" ID="ID_65877362" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1R2: 1.37-fold Up; FDR = 0.628; PValue = 0.35; mean CPM = 1.132; interleukin 1 receptor, type II" ID="ID_1291802823" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_1723283727" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STMN1: 1.15-fold Down; FDR = 0.684; PValue = 0.395; mean CPM = 43.13; Stathmin" ID="ID_108998821" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCD: 1.06-fold Up; FDR = 0.696; PValue = 0.404; mean CPM = 37.45; protein kinase C, delta" ID="ID_658968971" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCB: 1.86-fold Up; FDR = 0.727; PValue = 0.43; mean CPM = 0.8705; protein kinase C, beta" ID="ID_289752464" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPKAPK2: 1.06-fold Down; FDR = 0.733; PValue = 0.435; mean CPM = 82.16; mitogen-activated protein kinase-activated protein kinase 2" ID="ID_19280750" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_828209193" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZAK: 1.05-fold Down; FDR = 0.789; PValue = 0.486; mean CPM = 32.04; Mitogen-activated protein kinase kinase kinase MLT isoform 2; Uncharacterized protein" ID="ID_552205304" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRK: 1.05-fold Up; FDR = 0.791; PValue = 0.488; mean CPM = 59.92; v-crk sarcoma virus CT10 oncogene homolog (avian)" ID="ID_1585678585" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP5C: 1.05-fold Up; FDR = 0.826; PValue = 0.526; mean CPM = 49.97; protein phosphatase 5, catalytic subunit" ID="ID_194635522" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN7: 1.29-fold Up; FDR = 0.851; PValue = 0.562; mean CPM = 0.8740; protein tyrosine phosphatase, non-receptor type 7" ID="ID_721317660" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA5: 1.05-fold Up; FDR = 0.851; PValue = 0.562; mean CPM = 1754; heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)" ID="ID_697024228" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1947036304" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP4K1: 1.26-fold Up; FDR = 0.879; PValue = 0.598; mean CPM = 0.9281; mitogen-activated protein kinase kinase kinase kinase 1" ID="ID_1020434025" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_463876399" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK7: 1.04-fold Down; FDR = 0.899; PValue = 0.632; mean CPM = 16.93; Uncharacterized protein" ID="ID_171762448" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMEM37: 1.49-fold Down; FDR = 0.9; PValue = 0.636; mean CPM = 0.8533; transmembrane protein 37" ID="ID_1068459953" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB2: 1.05-fold Down; FDR = 0.903; PValue = 0.655; mean CPM = 110.8; transforming growth factor, beta 2" ID="ID_819694955" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP2: 1.05-fold Up; FDR = 0.906; PValue = 0.667; mean CPM = 12.88; caspase 2, apoptosis-related cysteine peptidase" ID="ID_553635836" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLA2G10: 1.15-fold Up; FDR = 0.907; PValue = 0.675; mean CPM = 1.118; phospholipase A2, group X" ID="ID_528273918" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASA1: 1.03-fold Down; FDR = 0.909; PValue = 0.69; mean CPM = 103.7; Ras GTPase-activating protein 1 isoform 1; Uncharacterized protein" ID="ID_1636272192" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NTF4: 1.14-fold Up; FDR = 0.911; PValue = 0.701; mean CPM = 0.7902; neurotrophin 4" ID="ID_1170956813" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK1: 1.03-fold Down; FDR = 0.911; PValue = 0.705; mean CPM = 18.65; p21 protein (Cdc42/Rac)-activated kinase 1" ID="ID_1653728627" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K2: 1.03-fold Up; FDR = 0.924; PValue = 0.73; mean CPM = 40.64; mitogen-activated protein kinase kinase kinase 2" ID="ID_708767020" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP4K3: 1.03-fold Down; FDR = 0.926; PValue = 0.732; mean CPM = 18.57; mitogen-activated protein kinase kinase kinase kinase 3" ID="ID_223410986" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB1: 1.02-fold Down; FDR = 0.936; PValue = 0.749; mean CPM = 62.61; transforming growth factor, beta 1" ID="ID_856491520" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FASLG: 1.2-fold Down; FDR = 0.941; PValue = 0.757; mean CPM = 0.8088; Fas ligand (TNF superfamily, member 6)" ID="ID_1405808569" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_1712382571" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC3: 1.03-fold Down; FDR = 0.952; PValue = 0.78; mean CPM = 13.31; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3" ID="ID_1068733070" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MOS: 1.02-fold Up; FDR = 0.958; PValue = 0.791; mean CPM = 0.8131; v-mos Moloney murine sarcoma viral oncogene homolog" ID="ID_38237264" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K13: 1.03-fold Up; FDR = 0.962; PValue = 0.796; mean CPM = 6.973; mitogen-activated protein kinase kinase kinase 13" ID="ID_1659963921" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_1064624577" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_1986319923" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NTRK1: 1.07-fold Up; FDR = 0.977; PValue = 0.82; mean CPM = 1.195; neurotrophic tyrosine kinase, receptor, type 1" ID="ID_1391378791" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GCK: 1.05-fold Up; FDR = 0.98; PValue = 0.824; mean CPM = 1.691; glucokinase (hexokinase 4)" ID="ID_430396147" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA3: 1.02-fold Up; FDR = 0.982; PValue = 0.829; mean CPM = 58.16; ribosomal protein S6 kinase, 90kDa, polypeptide 3" ID="ID_1596560676" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_705913486" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFRB: 1.01-fold Up; FDR = 1; PValue = 0.883; mean CPM = 391.1; platelet-derived growth factor receptor, beta polypeptide" ID="ID_1690978784" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGF: 1.06-fold Down; FDR = 1; PValue = 0.885; mean CPM = 0.8917; epidermal growth factor" ID="ID_1666854355" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPB2: 1.05-fold Down; FDR = 1; PValue = 0.889; mean CPM = 0.9668; heat shock 27kDa protein 2" ID="ID_891176817" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP9: 1.01-fold Up; FDR = 1; PValue = 0.908; mean CPM = 19.86; caspase 9, apoptosis-related cysteine peptidase" ID="ID_70416380" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK4: 1.19-fold Down; FDR = 1; PValue = 0.95; mean CPM = 0.8611; mitogen-activated protein kinase 4" ID="ID_1173430620" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLK: No Change; FDR = 1; PValue = 0.97; mean CPM = 11.78; nemo-like kinase" ID="ID_1978674455" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DAXX: No Change; FDR = 1; PValue = 0.984; mean CPM = 106.5; Death domain-associated protein 6 (Daxx)(hDaxx)(Fas death domain-associated protein)(ETS1-associated protein 1)(EAP1)" ID="ID_774750374" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACVR1B: No Change; FDR = 1; PValue = 0.999; mean CPM = 11.63; activin A receptor, type IB" ID="ID_1543579908" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SH2D1A: No Change; FDR = 1; PValue = 1; mean CPM = 0.7843; SH2 domain containing 1A" ID="ID_1028698200" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="TCR signaling: FDR = 0.00912, PValue = 0.00828" ID="ID_1591779189" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="IL15RA: 19.4-fold Up; FDR = 4.04e-17; PValue = 2.89e-19; mean CPM = 5.291; interleukin 15 receptor, alpha" ID="ID_1218535769" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK2: 3.75-fold Up; FDR = 6.1e-16; PValue = 5.38e-18; mean CPM = 68.21; receptor-interacting serine-threonine kinase 2" ID="ID_115868049" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_1799566849" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_792034473" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DBNL: 1.51-fold Down; FDR = 1.12e-07; PValue = 6.35e-09; mean CPM = 131.9; drebrin-like" ID="ID_1581241006" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2B: 3.54-fold Up; FDR = 1.24e-07; PValue = 7.07e-09; mean CPM = 5.971; PTK2B protein tyrosine kinase 2 beta" ID="ID_1987098105" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1075700608" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1037015183" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL10: 1.55-fold Up; FDR = 5.92e-06; PValue = 5.22e-07; mean CPM = 21.83; B-cell CLL/lymphoma 10" ID="ID_1805097350" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_71795762" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VIM: 1.54-fold Down; FDR = 0.000219; PValue = 3.01e-05; mean CPM = 3996; vimentin" ID="ID_988656951" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC2: 4.03-fold Down; FDR = 0.000346; PValue = 5.06e-05; mean CPM = 1.347; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2" ID="ID_1977991376" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF2: 1.34-fold Up; FDR = 0.000403; PValue = 6.01e-05; mean CPM = 39.83; activating transcription factor 2" ID="ID_720252681" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCK1: 1.39-fold Up; FDR = 0.000442; PValue = 6.67e-05; mean CPM = 21.55; NCK adaptor protein 1" ID="ID_843926168" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GATA3: 2.81-fold Up; FDR = 0.000734; PValue = 0.000119; mean CPM = 2.229; GATA binding protein 3" ID="ID_429564384" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GAB2: 1.33-fold Down; FDR = 0.00208; PValue = 0.000387; mean CPM = 22.59; GRB2-associated binding protein 2" ID="ID_515146558" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="REL: 1.46-fold Down; FDR = 0.00272; PValue = 0.000526; mean CPM = 10.17; v-rel avian reticuloendotheliosis viral oncogene homolog" ID="ID_1965695392" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG1: 1.31-fold Down; FDR = 0.00352; PValue = 0.000707; mean CPM = 53.66; phospholipase C, gamma 1" ID="ID_1553494935" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV3: 1.82-fold Down; FDR = 0.00463; PValue = 0.000973; mean CPM = 7.044; vav 3 guanine nucleotide exchange factor" ID="ID_1076781547" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1601752267" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K14: 1.47-fold Down; FDR = 0.00704; PValue = 0.00157; mean CPM = 9.470; mitogen-activated protein kinase kinase kinase 14" ID="ID_401068020" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SH2B3: 1.28-fold Up; FDR = 0.0133; PValue = 0.00326; mean CPM = 41.93; Uncharacterized protein" ID="ID_1050404763" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FYN: 1.22-fold Up; FDR = 0.0156; PValue = 0.00393; mean CPM = 92.94; FYN oncogene related to SRC, FGR, YES" ID="ID_1607841995" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_659234373" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CARD11: 1.31-fold Down; FDR = 0.0223; PValue = 0.00597; mean CPM = 58.32; caspase recruitment domain family, member 11" ID="ID_207582102" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1666392937" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_1361517100" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB1: 1.21-fold Up; FDR = 0.0313; PValue = 0.00884; mean CPM = 36.07; cAMP responsive element binding protein 1" ID="ID_765095004" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDPK1: 1.24-fold Down; FDR = 0.0361; PValue = 0.0105; mean CPM = 17.53; 3-phosphoinositide dependent protein kinase-1" ID="ID_1520645444" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_540549958" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_1766218761" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K8: 1.35-fold Down; FDR = 0.0831; PValue = 0.0281; mean CPM = 8.912; mitogen-activated protein kinase kinase kinase 8" ID="ID_46178173" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_819025517" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF4: 2.95-fold Down; FDR = 0.124; PValue = 0.0456; mean CPM = 0.9773; interferon regulatory factor 4" ID="ID_108284336" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_555776583" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1957879190" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1598022865" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_584070134" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAT: 1.44-fold Down; FDR = 0.234; PValue = 0.0996; mean CPM = 1.871; linker for activation of T cells" ID="ID_1511802082" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1A: 1.5-fold Up; FDR = 0.315; PValue = 0.144; mean CPM = 155.4; interleukin 1, alpha" ID="ID_91057657" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MALT1: 1.11-fold Down; FDR = 0.35; PValue = 0.164; mean CPM = 42.89; mucosa associated lymphoid tissue lymphoma translocation gene 1" ID="ID_1132580276" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRKL: 1.11-fold Up; FDR = 0.371; PValue = 0.176; mean CPM = 34.10; v-crk sarcoma virus CT10 oncogene homolog (avian)-like" ID="ID_597362147" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1940883130" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_176601434" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_165128894" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC1: 1.11-fold Down; FDR = 0.457; PValue = 0.23; mean CPM = 19.06; Uncharacterized protein" ID="ID_1924497046" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR5: 1.56-fold Down; FDR = 0.487; PValue = 0.249; mean CPM = 1.064; chemokine (C-C motif) receptor 5" ID="ID_610504436" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LCP2: 1.4-fold Up; FDR = 0.496; PValue = 0.256; mean CPM = 1.322; Uncharacterized protein" ID="ID_1095436275" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCQ: 1.56-fold Up; FDR = 0.522; PValue = 0.274; mean CPM = 1.047; Uncharacterized protein" ID="ID_1831486066" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDC42: 1.07-fold Down; FDR = 0.608; PValue = 0.335; mean CPM = 91.67; cell division cycle 42" ID="ID_1059080301" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_1985521422" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD247: 1.43-fold Down; FDR = 0.695; PValue = 0.404; mean CPM = 0.9076; Macaca mulatta CD247 molecule (CD247), mRNA." ID="ID_1811595207" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCD: 1.06-fold Up; FDR = 0.696; PValue = 0.404; mean CPM = 37.45; protein kinase C, delta" ID="ID_928142921" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRAP2: 1.31-fold Up; FDR = 0.701; PValue = 0.408; mean CPM = 3.696; GRB2-related adaptor protein 2" ID="ID_716314144" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WAS: 1.37-fold Down; FDR = 0.771; PValue = 0.469; mean CPM = 0.9085; Wiskott-Aldrich syndrome" ID="ID_1149673347" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRK: 1.05-fold Up; FDR = 0.791; PValue = 0.488; mean CPM = 59.92; v-crk sarcoma virus CT10 oncogene homolog (avian)" ID="ID_1029637378" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD4: 1.27-fold Up; FDR = 0.807; PValue = 0.503; mean CPM = 1.122; CD4 molecule" ID="ID_1842411626" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="OPRM1: 1.4-fold Down; FDR = 0.823; PValue = 0.522; mean CPM = 0.8003; Macaca mulatta opioid receptor, mu 1 (OPRM1), mRNA." ID="ID_1158758122" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CBL: 1.05-fold Down; FDR = 0.824; PValue = 0.524; mean CPM = 51.06; Cas-Br-M (murine) ecotropic retroviral transforming sequence" ID="ID_863059223" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SKAP1: 1.38-fold Up; FDR = 0.84; PValue = 0.546; mean CPM = 0.8034; src kinase associated phosphoprotein 1" ID="ID_1141161599" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1674920713" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV1: 1.25-fold Down; FDR = 0.858; PValue = 0.572; mean CPM = 0.9515; vav 1 guanine nucleotide exchange factor" ID="ID_1842719713" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CBLB: 1.04-fold Down; FDR = 0.859; PValue = 0.574; mean CPM = 64.59; Cas-Br-M (murine) ecotropic retroviral transforming sequence b" ID="ID_1483337920" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZAP70: 1.25-fold Down; FDR = 0.872; PValue = 0.59; mean CPM = 0.8996; zeta-chain (TCR) associated protein kinase 70kDa" ID="ID_606871652" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1696590681" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP4K1: 1.26-fold Up; FDR = 0.879; PValue = 0.598; mean CPM = 0.9281; mitogen-activated protein kinase kinase kinase kinase 1" ID="ID_1475545191" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3D: 1.22-fold Down; FDR = 0.903; PValue = 0.641; mean CPM = 0.7953; CD3d molecule, delta (CD3-TCR complex)" ID="ID_442819633" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF9: 1.28-fold Down; FDR = 0.911; PValue = 0.7; mean CPM = 0.8318; tumor necrosis factor receptor superfamily, member 9" ID="ID_1996160744" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK1: 1.03-fold Down; FDR = 0.911; PValue = 0.705; mean CPM = 18.65; p21 protein (Cdc42/Rac)-activated kinase 1" ID="ID_820136757" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL9: 1.14-fold Up; FDR = 0.911; PValue = 0.705; mean CPM = 0.7910; interleukin 9" ID="ID_1396839477" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17A: 1.12-fold Up; FDR = 0.911; PValue = 0.706; mean CPM = 0.7895; interleukin 17A" ID="ID_1378922916" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICOS: 1.19-fold Up; FDR = 0.931; PValue = 0.741; mean CPM = 0.8158; Uncharacterized protein" ID="ID_1999329410" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB1: 1.02-fold Down; FDR = 0.936; PValue = 0.749; mean CPM = 62.61; transforming growth factor, beta 1" ID="ID_478887016" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_763272135" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_1015269464" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITK: 1.07-fold Up; FDR = 1; PValue = 0.871; mean CPM = 0.9033; IL2-inducible T-cell kinase" ID="ID_19318454" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSTPIP1: 1.03-fold Down; FDR = 1; PValue = 0.929; mean CPM = 1.615; proline-serine-threonine phosphatase interacting protein 1" ID="ID_1705776749" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CGB8: 1.03-fold Down; FDR = 1; PValue = 0.967; mean CPM = 0.8727; Macaca mulatta chorionic gonadotropin, beta polypeptide 8 (CGB8), mRNA." ID="ID_1062995517" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3G: 1.03-fold Up; FDR = 1; PValue = 0.977; mean CPM = 0.8190; CD3g molecule, gamma (CD3-TCR complex)" ID="ID_1925325480" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD8A: No Change; FDR = 1; PValue = 0.98; mean CPM = 0.8052; CD8a molecule" ID="ID_55312374" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3E: 1.07-fold Down; FDR = 1; PValue = 0.981; mean CPM = 0.7994; Uncharacterized protein" ID="ID_28650370" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD83: No Change; FDR = 1; PValue = 0.996; mean CPM = 1.259; CD83 molecule" ID="ID_392524890" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="TGF-beta: FDR = 0.0216, PValue = 0.02" ID="ID_1936541318" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TGFB3: 4.82-fold Down; FDR = 1.82e-12; PValue = 3.09e-14; mean CPM = 9.911; transforming growth factor, beta 3" ID="ID_1255494957" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_139287644" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZFYVE9: 1.55-fold Up; FDR = 2.39e-08; PValue = 1.15e-09; mean CPM = 52.92; zinc finger, FYVE domain containing 9" ID="ID_468467931" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1487688658" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K3: 1.45-fold Down; FDR = 7.01e-06; PValue = 6.34e-07; mean CPM = 180.1; mitogen-activated protein kinase kinase 3" ID="ID_121307195" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_78028363" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF2: 1.34-fold Up; FDR = 0.000403; PValue = 6.01e-05; mean CPM = 39.83; activating transcription factor 2" ID="ID_1737603634" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD3: 1.38-fold Up; FDR = 0.000573; PValue = 8.94e-05; mean CPM = 114.9; SMAD family member 3" ID="ID_1610291947" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHOA: 1.28-fold Down; FDR = 0.00295; PValue = 0.000575; mean CPM = 277.8; ras homolog gene family, member A" ID="ID_1132884120" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD7: 1.33-fold Down; FDR = 0.00568; PValue = 0.00123; mean CPM = 67.59; SMAD family member 7" ID="ID_10611217" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_189080161" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD2: 1.2-fold Up; FDR = 0.034; PValue = 0.00976; mean CPM = 57.10; SMAD family member 2" ID="ID_1194981075" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFBR1: 1.2-fold Up; FDR = 0.037; PValue = 0.0108; mean CPM = 90.92; transforming growth factor, beta receptor 1" ID="ID_1366915247" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFBR2: 1.19-fold Up; FDR = 0.0643; PValue = 0.0208; mean CPM = 350.8; transforming growth factor, beta receptor II (70/80kDa)" ID="ID_793990491" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS2: 1.17-fold Up; FDR = 0.1; PValue = 0.0353; mean CPM = 31.79; son of sevenless homolog 2 (Drosophila)" ID="ID_1154310922" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_177299578" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XIAP: 1.17-fold Up; FDR = 0.177; PValue = 0.0706; mean CPM = 19.21; X-linked inhibitor of apoptosis" ID="ID_1610486430" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_187551129" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_66916679" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EP300: 1.11-fold Up; FDR = 0.312; PValue = 0.142; mean CPM = 162.8; E1A binding protein p300" ID="ID_266743083" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP1: 1.12-fold Down; FDR = 0.351; PValue = 0.165; mean CPM = 17.96; TGF-beta activated kinase 1/MAP3K7 binding protein 1" ID="ID_1739484934" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APC: 1.1-fold Down; FDR = 0.367; PValue = 0.174; mean CPM = 127.5; adenomatous polyposis coli" ID="ID_1790658346" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_988657254" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1510215826" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP4K1: 1.26-fold Up; FDR = 0.879; PValue = 0.598; mean CPM = 0.9281; mitogen-activated protein kinase kinase kinase kinase 1" ID="ID_1026094699" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NR2C2: 1.04-fold Down; FDR = 0.903; PValue = 0.641; mean CPM = 18.87; nuclear receptor subfamily 2, group C, member 2" ID="ID_855692116" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB2: 1.05-fold Down; FDR = 0.903; PValue = 0.655; mean CPM = 110.8; transforming growth factor, beta 2" ID="ID_658772550" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD4: 1.03-fold Down; FDR = 0.906; PValue = 0.666; mean CPM = 43.02; SMAD family member 4" ID="ID_863938947" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB1: 1.02-fold Down; FDR = 0.936; PValue = 0.749; mean CPM = 62.61; transforming growth factor, beta 1" ID="ID_474823413" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R4: 1.02-fold Down; FDR = 0.943; PValue = 0.763; mean CPM = 93.45; protein phosphatase 2A activator, regulatory subunit 4" ID="ID_1534945586" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SKIL: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 66.09; SKI-like oncogene" ID="ID_1850477189" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_29165291" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREBBP: 1.01-fold Down; FDR = 0.993; PValue = 0.847; mean CPM = 137.7; CREB binding protein" ID="ID_935551673" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_792948077" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDH1: 1.06-fold Down; FDR = 1; PValue = 0.899; mean CPM = 0.8823; cadherin 1, type 1, E-cadherin (epithelial)" ID="ID_1357066632" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- </node>
- <node TEXT="GlobalAncova gene set test" ID="ID_1540013332" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="IFN-gamma: FDR = 1.43e-10, PValue = 5.36e-12" ID="ID_1021462455" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="SP100: 3.56-fold Up; FDR = 3.74e-26; PValue = 1.58e-29; mean CPM = 187.4; SP100 nuclear antigen" ID="ID_1946868735" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF1: 18.6-fold Up; FDR = 1.53e-21; PValue = 4.24e-24; mean CPM = 240.7; interferon regulatory factor 1" ID="ID_1565987314" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR3: 10.3-fold Up; FDR = 1.95e-21; PValue = 5.6e-24; mean CPM = 35.70; toll-like receptor 3" ID="ID_1498239178" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF9: 3.85-fold Up; FDR = 2.6e-19; PValue = 1.12e-21; mean CPM = 106.4; interferon regulatory factor 9" ID="ID_1613030458" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_198373221" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_96464994" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF2: 3.25-fold Up; FDR = 2.61e-18; PValue = 1.48e-20; mean CPM = 32.37; interferon regulatory factor 2" ID="ID_1231970914" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF7: 14.8-fold Up; FDR = 7.66e-18; PValue = 4.82e-20; mean CPM = 11.54; Macaca mulatta interferon regulatory factor 7 (IRF7), mRNA." ID="ID_1759272604" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DMB: 17.5-fold Up; FDR = 2.77e-15; PValue = 2.66e-17; mean CPM = 9.464; HLA class II histocompatibility antigen, DM beta chain Precursor (MHC class II antigen DMB)(Really interesting new gene 7 protein)" ID="ID_1104768660" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DPA1: 107-fold Up; FDR = 5.97e-15; PValue = 6.11e-17; mean CPM = 17.08; HLA class II histocompatibility antigen, DP alpha 1 chain Precursor (HLA-SB alpha chain)(MHC class II DP3-alpha)(DP(W3))(DP(W4))" ID="ID_420665895" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DQB1: 31.1-fold Up; FDR = 6.93e-13; PValue = 1.1e-14; mean CPM = 6.675; Macaca mulatta MHC class II antigen (MAMU-DRB), mRNA." ID="ID_1624759168" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD276: 1.83-fold Down; FDR = 2.04e-11; PValue = 4.56e-13; mean CPM = 65.28; CD276 molecule" ID="ID_954926158" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PML: 2.25-fold Up; FDR = 6.36e-11; PValue = 1.6e-12; mean CPM = 94.89; Uncharacterized protein" ID="ID_882071761" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN2: 1.87-fold Up; FDR = 6.19e-10; PValue = 2e-11; mean CPM = 32.46; protein tyrosine phosphatase, non-receptor type 2" ID="ID_1163963667" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPRU: 2.57-fold Down; FDR = 1.5e-09; PValue = 5.3e-11; mean CPM = 17.80; Uncharacterized protein" ID="ID_556330882" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF8: 11.4-fold Up; FDR = 6e-09; PValue = 2.46e-10; mean CPM = 5.558; interferon regulatory factor 8" ID="ID_1168945909" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA1: 15.1-fold Up; FDR = 1.9e-08; PValue = 8.86e-10; mean CPM = 3.665; HLA class II histocompatibility antigen, DQ alpha 1 chain precursor" ID="ID_107885872" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DPB1: 7.73-fold Up; FDR = 4.73e-08; PValue = 2.45e-09; mean CPM = 1.528; Macaca mulatta major histocompatibility complex, class II, DP beta (MAMU-DPB), mRNA." ID="ID_402950760" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INHBA: 2.52-fold Down; FDR = 1.51e-07; PValue = 8.85e-09; mean CPM = 229.2; inhibin, beta A" ID="ID_1044476335" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CEBPG: 1.5-fold Up; FDR = 1.48e-05; PValue = 1.46e-06; mean CPM = 31.57; CCAAT/enhancer binding protein (C/EBP), gamma" ID="ID_907845543" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS3: 1.69-fold Up; FDR = 0.000994; PValue = 0.000167; mean CPM = 37.76; suppressor of cytokine signaling 3" ID="ID_891804466" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CISH: 1.95-fold Up; FDR = 0.00116; PValue = 0.0002; mean CPM = 5.083; cytokine inducible SH2-containing protein" ID="ID_1253645428" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR1: 1.31-fold Up; FDR = 0.00151; PValue = 0.000268; mean CPM = 37.77; interferon gamma receptor 1" ID="ID_981487053" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIAS1: 1.3-fold Up; FDR = 0.00259; PValue = 0.000498; mean CPM = 29.99; protein inhibitor of activated STAT, 1" ID="ID_154438185" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12A: 2.09-fold Up; FDR = 0.00924; PValue = 0.00215; mean CPM = 2.872; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)" ID="ID_276445884" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL18: 1.5-fold Down; FDR = 0.00981; PValue = 0.0023; mean CPM = 6.489; interleukin 18 (interferon-gamma-inducing factor)" ID="ID_1969955735" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INHA: 1.73-fold Down; FDR = 0.0134; PValue = 0.00329; mean CPM = 4.332; inhibin, alpha" ID="ID_1440706204" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FCGR2B: 2.01-fold Up; FDR = 0.0231; PValue = 0.00623; mean CPM = 1.743; Uncharacterized protein" ID="ID_1738958872" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR2: 1.23-fold Up; FDR = 0.0258; PValue = 0.00707; mean CPM = 46.52; interferon gamma receptor 2 (interferon gamma transducer 1)" ID="ID_305365354" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN1: 1.2-fold Down; FDR = 0.0495; PValue = 0.0152; mean CPM = 35.05; protein tyrosine phosphatase, non-receptor type 1" ID="ID_1982242145" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DOA: 2.74-fold Up; FDR = 0.0694; PValue = 0.0227; mean CPM = 0.9089; HLA class II histocompatibility antigen, DO alpha chain Precursor (MHC class II antigen DOA)(MHC DZ alpha)(MHC DN-alpha)" ID="ID_1051694414" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_187340129" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF4: 2.95-fold Down; FDR = 0.124; PValue = 0.0456; mean CPM = 0.9773; interferon regulatory factor 4" ID="ID_1048455169" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FCGR2A: 2.18-fold Up; FDR = 0.172; PValue = 0.0682; mean CPM = 0.9955; Fc fragment of IgG, low affinity IIa, receptor (CD32)" ID="ID_1991198565" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EBI3: 1.84-fold Up; FDR = 0.228; PValue = 0.0966; mean CPM = 1.386; Epstein-Barr virus induced 3" ID="ID_1772142160" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL27: 1.82-fold Down; FDR = 0.302; PValue = 0.137; mean CPM = 0.9530; interleukin 27" ID="ID_220166152" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014796: 1.77-fold Up; FDR = 0.381; PValue = 0.182; mean CPM = 0.9085; Uncharacterized protein" ID="ID_723273999" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016250: 1.52-fold Up; FDR = 0.419; PValue = 0.205; mean CPM = 1.143" ID="ID_1636300058" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_1090394225" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF6: 2.34-fold Down; FDR = 0.535; PValue = 0.283; mean CPM = 0.8609; interferon regulatory factor 6" ID="ID_1759585181" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCD: 1.06-fold Up; FDR = 0.696; PValue = 0.404; mean CPM = 37.45; protein kinase C, delta" ID="ID_301136366" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF9: 1.77-fold Up; FDR = 0.74; PValue = 0.441; mean CPM = 0.8485; fibroblast growth factor 9 (glia-activating factor)" ID="ID_649861627" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF5: 1.06-fold Down; FDR = 0.85; PValue = 0.561; mean CPM = 9.280; interferon regulatory factor 5" ID="ID_1932237332" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR7: 1.37-fold Down; FDR = 0.878; PValue = 0.597; mean CPM = 0.8402; toll-like receptor 7" ID="ID_1328449340" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MT2A: 1.24-fold Up; FDR = 0.893; PValue = 0.618; mean CPM = 0.9117; metallothionein 2A" ID="ID_1942541754" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DRB: 1.28-fold Up; FDR = 0.898; PValue = 0.624; mean CPM = 0.8112; MHC class II antigen; Uncharacterized protein" ID="ID_1156751263" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_152229148" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTAFR: 1.39-fold Down; FDR = 0.906; PValue = 0.67; mean CPM = 0.8209; platelet-activating factor receptor" ID="ID_939726742" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA2: 1.13-fold Up; FDR = 0.908; PValue = 0.681; mean CPM = 0.7877; HLA class II histocompatibility antigen, DQ alpha 2 chain Precursor (HLA class II histocompatibility antigen, DQ(6) alpha chain)(DX alpha chain)(HLA-DQA1)" ID="ID_770727836" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000028965: 1.11-fold Up; FDR = 0.911; PValue = 0.697; mean CPM = 1.501; Uncharacterized protein" ID="ID_1746470867" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12B: 1.07-fold Up; FDR = 0.983; PValue = 0.831; mean CPM = 0.8197; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)" ID="ID_832296963" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR9: 1.01-fold Down; FDR = 1; PValue = 0.859; mean CPM = 21.45; Macaca mulatta toll-like receptor 9 (TLR9), mRNA." ID="ID_937217947" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="REG1A: No Change; FDR = 1; PValue = 1; mean CPM = 0.7990; regenerating islet-derived 1 alpha" ID="ID_912721701" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="REG1A: No Change; FDR = 1; PValue = 1; mean CPM = 0.7825; Uncharacterized protein" ID="ID_1725978195" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000025091: No Change; FDR = 1; PValue = 1; mean CPM = 0.7808; Uncharacterized protein" ID="ID_760335882" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLA2G2A: No Change; FDR = 1; PValue = 1; mean CPM = 0.7858; phospholipase A2, group IIA (platelets, synovial fluid)" ID="ID_1188647361" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Toll-like receptor signaling: FDR = 1.43e-10, PValue = 8.12e-12" ID="ID_1801244880" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TLR2: 8.94-fold Up; FDR = 6.97e-23; PValue = 1.25e-25; mean CPM = 18.41; toll-like receptor 2" ID="ID_347905061" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL10: 462-fold Up; FDR = 1.01e-21; PValue = 2.65e-24; mean CPM = 286.2; Macaca mulatta chemokine (C-X-C motif) ligand 10 (CXCL10), mRNA." ID="ID_1381773451" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR3: 10.3-fold Up; FDR = 1.95e-21; PValue = 5.6e-24; mean CPM = 35.70; toll-like receptor 3" ID="ID_1740084212" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL11: 256-fold Up; FDR = 1e-19; PValue = 3.96e-22; mean CPM = 84.82; chemokine (C-X-C motif) ligand 11" ID="ID_387368106" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL9: 345-fold Up; FDR = 4.16e-19; PValue = 1.97e-21; mean CPM = 175.7; Macaca mulatta chemokine (C-X-C motif) ligand 9 (CXCL9), mRNA." ID="ID_1376493203" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1634761578" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF7: 14.8-fold Up; FDR = 7.66e-18; PValue = 4.82e-20; mean CPM = 11.54; Macaca mulatta interferon regulatory factor 7 (IRF7), mRNA." ID="ID_804790298" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_182347021" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LY96: 3.13-fold Up; FDR = 1.27e-10; PValue = 3.43e-12; mean CPM = 6.127; lymphocyte antigen 96" ID="ID_1603580867" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR4: 3.45-fold Up; FDR = 3.1e-09; PValue = 1.19e-10; mean CPM = 7.456; Macaca mulatta toll-like receptor 4 (TLR4), mRNA." ID="ID_1567454890" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_128750402" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK4: 1.8-fold Up; FDR = 3.31e-08; PValue = 1.64e-09; mean CPM = 12.89; interleukin-1 receptor-associated kinase 4" ID="ID_1565691784" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1566281460" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL5: 6.74-fold Up; FDR = 2.65e-07; PValue = 1.64e-08; mean CPM = 30.35; chemokine (C-C motif) ligand 5" ID="ID_1066780" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1202169192" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD14: 2.75-fold Down; FDR = 6.54e-07; PValue = 4.46e-08; mean CPM = 5.195; CD14 molecule" ID="ID_1175603674" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_6379095" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_1204066353" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR2: 1.74-fold Up; FDR = 1.85e-06; PValue = 1.44e-07; mean CPM = 26.05; interferon (alpha, beta and omega) receptor 2" ID="ID_1246340071" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1082137885" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K3: 1.45-fold Down; FDR = 7.01e-06; PValue = 6.34e-07; mean CPM = 180.1; mitogen-activated protein kinase kinase 3" ID="ID_1661664392" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1880379633" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPP1: 2.25-fold Down; FDR = 7.74e-05; PValue = 9.29e-06; mean CPM = 35.33; secreted phosphoprotein 1" ID="ID_985262204" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP2: 1.45-fold Up; FDR = 0.000179; PValue = 2.4e-05; mean CPM = 65.31; TGF-beta activated kinase 1/MAP3K7 binding protein 2" ID="ID_1365557504" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40: 2.76-fold Up; FDR = 0.00039; PValue = 5.79e-05; mean CPM = 9.139; CD40 molecule, TNF receptor superfamily member 5" ID="ID_1847162791" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TOLLIP: 1.36-fold Down; FDR = 0.000551; PValue = 8.57e-05; mean CPM = 28.79; Uncharacterized protein" ID="ID_1184659186" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTSK: 1.62-fold Down; FDR = 0.00104; PValue = 0.000176; mean CPM = 20.16; cathepsin K" ID="ID_564263213" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBK1: 1.3-fold Up; FDR = 0.00337; PValue = 0.000674; mean CPM = 30.46; TANK-binding kinase 1" ID="ID_382958318" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1876659056" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_1058186953" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR5: 1.86-fold Down; FDR = 0.00878; PValue = 0.00203; mean CPM = 3.008; toll-like receptor 5" ID="ID_674144467" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12A: 2.09-fold Up; FDR = 0.00924; PValue = 0.00215; mean CPM = 2.872; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)" ID="ID_1633166424" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR1: 1.27-fold Up; FDR = 0.0101; PValue = 0.00237; mean CPM = 82.39; Uncharacterized protein" ID="ID_563053403" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_37957657" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL8: 2.33-fold Up; FDR = 0.0209; PValue = 0.00552; mean CPM = 2326; interleukin 8" ID="ID_1349075816" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_728219017" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_1896622825" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1543340098" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL3: 2.04-fold Down; FDR = 0.067; PValue = 0.0218; mean CPM = 3.575; chemokine (C-C motif) ligand 3" ID="ID_1688502675" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K8: 1.35-fold Down; FDR = 0.0831; PValue = 0.0281; mean CPM = 8.912; mitogen-activated protein kinase kinase kinase 8" ID="ID_117695220" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FADD: 1.18-fold Down; FDR = 0.0936; PValue = 0.0324; mean CPM = 30.89; Uncharacterized protein" ID="ID_1497438531" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_316014889" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_479512183" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_645645290" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_1267426646" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_723194233" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP1: 1.12-fold Down; FDR = 0.351; PValue = 0.165; mean CPM = 17.96; TGF-beta activated kinase 1/MAP3K7 binding protein 1" ID="ID_1653696891" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_16751984" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TICAM1: 1.11-fold Down; FDR = 0.398; PValue = 0.192; mean CPM = 26.73; toll-like receptor adaptor molecule 1" ID="ID_410098999" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_1625200834" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1880575166" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK12: 1.19-fold Down; FDR = 0.422; PValue = 0.208; mean CPM = 6.569; mitogen-activated protein kinase 12" ID="ID_890753067" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1898416688" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_342457279" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK13: 1.22-fold Down; FDR = 0.536; PValue = 0.284; mean CPM = 3.100; mitogen-activated protein kinase 13" ID="ID_507291960" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LBP: 1.52-fold Down; FDR = 0.591; PValue = 0.324; mean CPM = 0.8819; lipopolysaccharide binding protein" ID="ID_122299256" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF3: 1.07-fold Up; FDR = 0.611; PValue = 0.338; mean CPM = 34.56; TNF receptor-associated factor 3" ID="ID_1053158252" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_1620525678" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNB1: 1.79-fold Up; FDR = 0.731; PValue = 0.433; mean CPM = 0.8526; interferon, beta 1, fibroblast" ID="ID_68085656" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA6: 1.41-fold Down; FDR = 0.807; PValue = 0.504; mean CPM = 0.8019; interferon, alpha 6" ID="ID_914026810" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR6: 1.07-fold Down; FDR = 0.84; PValue = 0.546; mean CPM = 7.909; toll-like receptor 6" ID="ID_812704742" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TIRAP: 1.07-fold Up; FDR = 0.841; PValue = 0.548; mean CPM = 8.693; Macaca mulatta toll-interleukin 1 receptor (TIR) domain containing adaptor protein (TIRAP), mRNA." ID="ID_900717521" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF5: 1.06-fold Down; FDR = 0.85; PValue = 0.561; mean CPM = 9.280; interferon regulatory factor 5" ID="ID_1465960712" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1161487105" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1825392367" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR7: 1.37-fold Down; FDR = 0.878; PValue = 0.597; mean CPM = 0.8402; toll-like receptor 7" ID="ID_239401409" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK1: 1.04-fold Down; FDR = 0.885; PValue = 0.606; mean CPM = 41.54; interleukin-1 receptor-associated kinase 1" ID="ID_1367056515" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_1915754472" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA13: 1.13-fold Up; FDR = 0.908; PValue = 0.677; mean CPM = 0.7960; interferon, alpha 13" ID="ID_102293169" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA8: 1.13-fold Down; FDR = 0.911; PValue = 0.702; mean CPM = 0.7910; interferon, alpha 8" ID="ID_1422334273" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKE: 1.03-fold Up; FDR = 0.929; PValue = 0.737; mean CPM = 21.61; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon" ID="ID_155967479" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA14: 1.22-fold Up; FDR = 0.965; PValue = 0.802; mean CPM = 0.8654; interferon, alpha 14" ID="ID_57220769" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_447459803" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD80: 1.08-fold Up; FDR = 0.971; PValue = 0.812; mean CPM = 1.157; CD80 molecule" ID="ID_130936877" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_615778553" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA4: 1.28-fold Down; FDR = 0.983; PValue = 0.829; mean CPM = 0.8584; interferon, alpha 4" ID="ID_1066922451" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12B: 1.07-fold Up; FDR = 0.983; PValue = 0.831; mean CPM = 0.8197; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)" ID="ID_1204270304" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_1678047822" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR9: 1.01-fold Down; FDR = 1; PValue = 0.859; mean CPM = 21.45; Macaca mulatta toll-like receptor 9 (TLR9), mRNA." ID="ID_936151829" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR1: 1.02-fold Up; FDR = 1; PValue = 0.945; mean CPM = 1.221; toll-like receptor 1" ID="ID_1089902351" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD86: 1.01-fold Down; FDR = 1; PValue = 0.99; mean CPM = 0.8012; CD86 molecule" ID="ID_433268137" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA1: No Change; FDR = 1; PValue = 0.998; mean CPM = 0.8014; interferon, alpha 1" ID="ID_1581660091" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-12: FDR = 1.43e-10, PValue = 1.23e-11" ID="ID_1359736984" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TLR2: 8.94-fold Up; FDR = 6.97e-23; PValue = 1.25e-25; mean CPM = 18.41; toll-like receptor 2" ID="ID_1065080033" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF1: 18.6-fold Up; FDR = 1.53e-21; PValue = 4.24e-24; mean CPM = 240.7; interferon regulatory factor 1" ID="ID_1702195515" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_434722258" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_725085867" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR4: 3.45-fold Up; FDR = 3.1e-09; PValue = 1.19e-10; mean CPM = 7.456; Macaca mulatta toll-like receptor 4 (TLR4), mRNA." ID="ID_71310541" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF8: 11.4-fold Up; FDR = 6e-09; PValue = 2.46e-10; mean CPM = 5.558; interferon regulatory factor 8" ID="ID_332879510" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1894697098" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_84971444" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_476278687" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1899940250" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZNF668: 1.55-fold Down; FDR = 3.17e-06; PValue = 2.59e-07; mean CPM = 25.80; zinc finger protein 668" ID="ID_368419865" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ETV5: 1.43-fold Up; FDR = 5.02e-06; PValue = 4.33e-07; mean CPM = 61.45; ets variant 5" ID="ID_366831948" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL18R1: 3.18-fold Down; FDR = 5.89e-06; PValue = 5.19e-07; mean CPM = 3.445; interleukin 18 receptor 1" ID="ID_1713632481" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_81123991" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT4: 1.79-fold Up; FDR = 2.3e-05; PValue = 2.36e-06; mean CPM = 26.79; signal transducer and activator of transcription 4" ID="ID_1193946805" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JMJD6: 1.38-fold Down; FDR = 4.61e-05; PValue = 5.17e-06; mean CPM = 47.49; jumonji domain containing 6" ID="ID_785250264" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_1462327143" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40: 2.76-fold Up; FDR = 0.00039; PValue = 5.79e-05; mean CPM = 9.139; CD40 molecule, TNF receptor superfamily member 5" ID="ID_646204528" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR1: 1.31-fold Up; FDR = 0.00151; PValue = 0.000268; mean CPM = 37.77; interferon gamma receptor 1" ID="ID_1938590838" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRRT2: 3.34-fold Down; FDR = 0.00175; PValue = 0.000318; mean CPM = 1.259; proline-rich transmembrane protein 2" ID="ID_148232646" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="REL: 1.46-fold Down; FDR = 0.00272; PValue = 0.000526; mean CPM = 10.17; v-rel avian reticuloendotheliosis viral oncogene homolog" ID="ID_1710758148" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MST1: 1.59-fold Down; FDR = 0.0041; PValue = 0.000845; mean CPM = 4.582; Uncharacterized protein" ID="ID_106177386" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_121833306" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MST1R: 1.36-fold Up; FDR = 0.00791; PValue = 0.00179; mean CPM = 15.65; macrophage stimulating 1 receptor (c-met-related tyrosine kinase)" ID="ID_1312769126" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12A: 2.09-fold Up; FDR = 0.00924; PValue = 0.00215; mean CPM = 2.872; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)" ID="ID_1809061527" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL18: 1.5-fold Down; FDR = 0.00981; PValue = 0.0023; mean CPM = 6.489; interleukin 18 (interferon-gamma-inducing factor)" ID="ID_1411487075" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYK2: 1.24-fold Down; FDR = 0.0142; PValue = 0.00354; mean CPM = 42.58; tyrosine kinase 2" ID="ID_37334114" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAB7B: 1.54-fold Down; FDR = 0.0162; PValue = 0.00413; mean CPM = 7.015; Uncharacterized protein" ID="ID_1031101407" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_938438105" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_692608731" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_1523110083" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1868658325" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELB: 1.22-fold Down; FDR = 0.0606; PValue = 0.0193; mean CPM = 26.64; v-rel reticuloendotheliosis viral oncogene homolog B" ID="ID_986371407" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT6: 1.18-fold Up; FDR = 0.0727; PValue = 0.024; mean CPM = 217.5; signal transducer and activator of transcription 6, interleukin-4 induced" ID="ID_1474517238" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RXRA: 1.18-fold Down; FDR = 0.077; PValue = 0.0257; mean CPM = 35.60; retinoid X receptor, alpha" ID="ID_1128240922" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K8: 1.35-fold Down; FDR = 0.0831; PValue = 0.0281; mean CPM = 8.912; mitogen-activated protein kinase kinase kinase 8" ID="ID_1987696912" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCOA1: 1.18-fold Up; FDR = 0.112; PValue = 0.04; mean CPM = 20.42; nuclear receptor coactivator 1" ID="ID_1107180321" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_775328752" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_28513283" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ALOX15: 2-fold Down; FDR = 0.194; PValue = 0.0791; mean CPM = 0.9607; arachidonate 15-lipoxygenase" ID="ID_1385862818" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAB7A: 1.12-fold Down; FDR = 0.229; PValue = 0.097; mean CPM = 112.6; RAB7A, member RAS oncogene family" ID="ID_546579806" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12RB2: 1.42-fold Down; FDR = 0.299; PValue = 0.135; mean CPM = 1.728; interleukin 12 receptor, beta 2" ID="ID_1624561083" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EP300: 1.11-fold Up; FDR = 0.312; PValue = 0.142; mean CPM = 162.8; E1A binding protein p300" ID="ID_367967350" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_48975000" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL23A: 1.39-fold Up; FDR = 0.348; PValue = 0.163; mean CPM = 4.542; interleukin 23, alpha subunit p19" ID="ID_221713922" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1088761450" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_178875450" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_851486423" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_417963128" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR5: 1.56-fold Down; FDR = 0.487; PValue = 0.249; mean CPM = 1.064; chemokine (C-C motif) receptor 5" ID="ID_349370981" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_250381654" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF6: 2.34-fold Down; FDR = 0.535; PValue = 0.283; mean CPM = 0.8609; interferon regulatory factor 6" ID="ID_993542679" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD247: 1.43-fold Down; FDR = 0.695; PValue = 0.404; mean CPM = 0.9076; Macaca mulatta CD247 molecule (CD247), mRNA." ID="ID_1206476710" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12RB1: 1.39-fold Up; FDR = 0.703; PValue = 0.41; mean CPM = 0.9665; interleukin 12 receptor, beta 1" ID="ID_978100089" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_300392373" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_315366657" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_526848792" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3D: 1.22-fold Down; FDR = 0.903; PValue = 0.641; mean CPM = 0.7953; CD3d molecule, delta (CD3-TCR complex)" ID="ID_1127612324" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOS2: 1.4-fold Down; FDR = 0.917; PValue = 0.718; mean CPM = 0.8546; nitric oxide synthase 2, inducible" ID="ID_993498029" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL4: 1.27-fold Down; FDR = 0.933; PValue = 0.745; mean CPM = 0.8077; interleukin 4" ID="ID_1304349572" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPI1: 1.12-fold Down; FDR = 0.935; PValue = 0.747; mean CPM = 1.030; spleen focus forming virus (SFFV) proviral integration oncogene spi1" ID="ID_458153000" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB1: 1.02-fold Down; FDR = 0.936; PValue = 0.749; mean CPM = 62.61; transforming growth factor, beta 1" ID="ID_1459322340" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12B: 1.07-fold Up; FDR = 0.983; PValue = 0.831; mean CPM = 0.8197; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)" ID="ID_210853839" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ALOX12: 1.01-fold Up; FDR = 1; PValue = 0.927; mean CPM = 12.39; arachidonate 12-lipoxygenase" ID="ID_595301369" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPARG: 1.01-fold Down; FDR = 1; PValue = 0.929; mean CPM = 5.609; peroxisome proliferator-activated receptor gamma" ID="ID_1910681210" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCR3: 1.03-fold Up; FDR = 1; PValue = 0.943; mean CPM = 0.9843; chemokine (C-X-C motif) receptor 3" ID="ID_374415506" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_774674550" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL10: 1.21-fold Down; FDR = 1; PValue = 0.964; mean CPM = 0.8614; interleukin 10" ID="ID_1059617416" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3G: 1.03-fold Up; FDR = 1; PValue = 0.977; mean CPM = 0.8190; CD3g molecule, gamma (CD3-TCR complex)" ID="ID_1988736430" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3E: 1.07-fold Down; FDR = 1; PValue = 0.981; mean CPM = 0.7994; Uncharacterized protein" ID="ID_921496950" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40LG: 1.01-fold Down; FDR = 1; PValue = 0.982; mean CPM = 0.8653; CD40 ligand" ID="ID_935607307" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL23R: 1.05-fold Down; FDR = 1; PValue = 0.994; mean CPM = 0.7958; interleukin 23 receptor" ID="ID_780829305" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA1: No Change; FDR = 1; PValue = 0.998; mean CPM = 0.8014; interferon, alpha 1" ID="ID_15866581" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Antigen processing and presentation: FDR = 1.43e-10, PValue = 1.35e-11" ID="ID_1514065864" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TAP1: 8.86-fold Up; FDR = 4.25e-27; PValue = 3.99e-31; mean CPM = 524.4; Antigen peptide transporter 1 (APT1)(Peptide transporter TAP1)(ATP-binding cassette sub-family B member 2)(Peptide supply factor 1)(Peptide transporter PSF1)(PSF-1)(Peptide transporter involved in antigen processing 1)(Really interesting new gene 4 /.../n)" ID="ID_1706263340" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014803: 6.92-fold Up; FDR = 4.41e-27; PValue = 6.21e-31; mean CPM = 361.1; Uncharacterized protein" ID="ID_889719832" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTSS: 17.2-fold Up; FDR = 6.21e-25; PValue = 3.79e-28; mean CPM = 42.75; cathepsin S" ID="ID_1841564071" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSME1: 5.25-fold Up; FDR = 7.8e-24; PValue = 9.53e-27; mean CPM = 157.6; Uncharacterized protein" ID="ID_1305734623" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFI30: 14.5-fold Up; FDR = 1.96e-22; PValue = 4.32e-25; mean CPM = 117.9; interferon, gamma-inducible protein 30" ID="ID_509036921" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000027180: 6.97-fold Up; FDR = 1.24e-21; PValue = 3.39e-24; mean CPM = 285.4; Uncharacterized protein" ID="ID_1618996913" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000027180: 6.97-fold Up; FDR = 1.24e-21; PValue = 3.39e-24; mean CPM = 285.4; Uncharacterized protein" ID="ID_1970114397" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000005183: 4.07-fold Up; FDR = 2.87e-21; PValue = 8.51e-24; mean CPM = 164.7; Uncharacterized protein" ID="ID_659843073" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000005183: 4.07-fold Up; FDR = 2.87e-21; PValue = 8.51e-24; mean CPM = 164.7; Uncharacterized protein" ID="ID_1545664763" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-B: 6.07-fold Up; FDR = 2.71e-19; PValue = 1.2e-21; mean CPM = 2098; Uncharacterized protein" ID="ID_613478587" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CIITA: 45.8-fold Up; FDR = 1.14e-17; PValue = 7.44e-20; mean CPM = 27.80; class II, major histocompatibility complex, transactivator" ID="ID_987188525" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD74: 104-fold Up; FDR = 6e-17; PValue = 4.54e-19; mean CPM = 141.5; CD74 molecule, major histocompatibility complex, class II invariant chain" ID="ID_876933721" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DMB: 17.5-fold Up; FDR = 2.77e-15; PValue = 2.66e-17; mean CPM = 9.464; HLA class II histocompatibility antigen, DM beta chain Precursor (MHC class II antigen DMB)(Really interesting new gene 7 protein)" ID="ID_600137745" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DPA1: 107-fold Up; FDR = 5.97e-15; PValue = 6.11e-17; mean CPM = 17.08; HLA class II histocompatibility antigen, DP alpha 1 chain Precursor (HLA-SB alpha chain)(MHC class II DP3-alpha)(DP(W3))(DP(W4))" ID="ID_915904608" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA2: 4.21-fold Down; FDR = 2.4e-14; PValue = 2.77e-16; mean CPM = 66.42; heat shock 70kDa protein 2" ID="ID_832232454" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DQB1: 31.1-fold Up; FDR = 6.93e-13; PValue = 1.1e-14; mean CPM = 6.675; Macaca mulatta MHC class II antigen (MAMU-DRB), mRNA." ID="ID_307276891" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA1B: 2.24-fold Down; FDR = 4.33e-09; PValue = 1.71e-10; mean CPM = 44.90; Heat shock 70 kDa protein 1A/1B (Heat shock 70 kDa protein 1/2)(HSP70.1/HSP70.2)(HSP70-1/HSP70-2)" ID="ID_1756971537" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALR: 1.71-fold Down; FDR = 1.22e-08; PValue = 5.36e-10; mean CPM = 674.0; calreticulin" ID="ID_4732240" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA8: 1.64-fold Up; FDR = 1.46e-08; PValue = 6.6e-10; mean CPM = 1881; heat shock 70kDa protein 8" ID="ID_1937808532" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA1: 15.1-fold Up; FDR = 1.9e-08; PValue = 8.86e-10; mean CPM = 3.665; HLA class II histocompatibility antigen, DQ alpha 1 chain precursor" ID="ID_935921035" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DPB1: 7.73-fold Up; FDR = 4.73e-08; PValue = 2.45e-09; mean CPM = 1.528; Macaca mulatta major histocompatibility complex, class II, DP beta (MAMU-DPB), mRNA." ID="ID_889512068" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTSL1: 1.84-fold Up; FDR = 6.74e-08; PValue = 3.62e-09; mean CPM = 326.4; cathepsin L1" ID="ID_1934550773" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RFX5: 1.45-fold Up; FDR = 2.02e-06; PValue = 1.58e-07; mean CPM = 51.69; regulatory factor X, 5 (influences HLA class II expression)" ID="ID_1801437217" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90AA1: 1.41-fold Up; FDR = 4.17e-05; PValue = 4.62e-06; mean CPM = 609.6; heat shock protein 90kDa alpha (cytosolic), class A member 2" ID="ID_447029380" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA6: 2.05-fold Down; FDR = 0.0226; PValue = 0.00604; mean CPM = 2.573; heat shock 70kDa protein 6 (HSP70B')" ID="ID_663688224" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB1: 1.21-fold Up; FDR = 0.0313; PValue = 0.00884; mean CPM = 36.07; cAMP responsive element binding protein 1" ID="ID_885304482" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DOA: 2.74-fold Up; FDR = 0.0694; PValue = 0.0227; mean CPM = 0.9089; HLA class II histocompatibility antigen, DO alpha chain Precursor (MHC class II antigen DOA)(MHC DZ alpha)(MHC DN-alpha)" ID="ID_1365674642" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDIA3: 1.17-fold Up; FDR = 0.11; PValue = 0.0393; mean CPM = 521.1; protein disulfide isomerase family A, member 3" ID="ID_694576085" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RFXANK: 1.15-fold Up; FDR = 0.166; PValue = 0.0651; mean CPM = 33.20; regulatory factor X-associated ankyrin-containing protein" ID="ID_1589371402" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFYA: 1.14-fold Up; FDR = 0.174; PValue = 0.069; mean CPM = 34.54; nuclear transcription factor Y, alpha" ID="ID_1224756003" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014796: 1.77-fold Up; FDR = 0.381; PValue = 0.182; mean CPM = 0.9085; Uncharacterized protein" ID="ID_423445983" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTSB: 1.09-fold Up; FDR = 0.489; PValue = 0.251; mean CPM = 270.7; cathepsin B" ID="ID_1727766752" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFYB: 1.1-fold Up; FDR = 0.547; PValue = 0.292; mean CPM = 15.90; nuclear transcription factor Y, beta" ID="ID_1272875939" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RFXAP: 1.18-fold Up; FDR = 0.553; PValue = 0.296; mean CPM = 3.588; regulatory factor X-associated protein" ID="ID_614563855" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90AB1: 1.07-fold Down; FDR = 0.652; PValue = 0.369; mean CPM = 905.8; heat shock protein 90kDa alpha (cytosolic), class B member 1" ID="ID_630731039" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90AA1: 1.8-fold Up; FDR = 0.749; PValue = 0.449; mean CPM = 0.8328; heat shock protein 90kDa alpha (cytosolic), class A member 1" ID="ID_882467601" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD4: 1.27-fold Up; FDR = 0.807; PValue = 0.503; mean CPM = 1.122; CD4 molecule" ID="ID_1346732614" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA6: 1.41-fold Down; FDR = 0.807; PValue = 0.504; mean CPM = 0.8019; interferon, alpha 6" ID="ID_34904146" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA5: 1.05-fold Up; FDR = 0.851; PValue = 0.562; mean CPM = 1754; heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)" ID="ID_115436169" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA4: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 217.6; heat shock 70kDa protein 4" ID="ID_604071487" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CANX: 1.04-fold Up; FDR = 0.859; PValue = 0.573; mean CPM = 348.2; calnexin" ID="ID_298375152" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000024066: 1.25-fold Up; FDR = 0.896; PValue = 0.621; mean CPM = 0.7972; Uncharacterized protein" ID="ID_115836871" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DRB: 1.28-fold Up; FDR = 0.898; PValue = 0.624; mean CPM = 0.8112; MHC class II antigen; Uncharacterized protein" ID="ID_877818478" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KLRC1: 1.14-fold Down; FDR = 0.903; PValue = 0.653; mean CPM = 1.817; killer cell lectin-like receptor subfamily C, member 1" ID="ID_618285031" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA13: 1.13-fold Up; FDR = 0.908; PValue = 0.677; mean CPM = 0.7960; interferon, alpha 13" ID="ID_987763553" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA2: 1.13-fold Up; FDR = 0.908; PValue = 0.681; mean CPM = 0.7877; HLA class II histocompatibility antigen, DQ alpha 2 chain Precursor (HLA class II histocompatibility antigen, DQ(6) alpha chain)(DX alpha chain)(HLA-DQA1)" ID="ID_871328559" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA8: 1.13-fold Down; FDR = 0.911; PValue = 0.702; mean CPM = 0.7910; interferon, alpha 8" ID="ID_1997655125" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KIR3DL2: 1.18-fold Down; FDR = 0.944; PValue = 0.764; mean CPM = 0.8149; Macaca mulatta killer immunoglobulin-like receptor KIR3DL20 (KIR3DL20), mRNA." ID="ID_1579813563" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA14: 1.22-fold Up; FDR = 0.965; PValue = 0.802; mean CPM = 0.8654; interferon, alpha 14" ID="ID_1233466422" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA4: 1.28-fold Down; FDR = 0.983; PValue = 0.829; mean CPM = 0.8584; interferon, alpha 4" ID="ID_1070733762" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSME3: No Change; FDR = 1; PValue = 0.946; mean CPM = 64.75; proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)" ID="ID_177088335" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LGMN: No Change; FDR = 1; PValue = 0.967; mean CPM = 458.0; legumain" ID="ID_586673551" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD8A: No Change; FDR = 1; PValue = 0.98; mean CPM = 0.8052; CD8a molecule" ID="ID_720072839" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA1: No Change; FDR = 1; PValue = 0.998; mean CPM = 0.8014; interferon, alpha 1" ID="ID_1603039021" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KLRD1: No Change; FDR = 1; PValue = 1; mean CPM = 0.7825; Macaca mulatta killer cell lectin-like receptor subfamily D, member 1 (KLRD1), mRNA." ID="ID_580548968" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-6 : FDR = 1.43e-10, PValue = 1.38e-11" ID="ID_1980008167" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="IRF1: 18.6-fold Up; FDR = 1.53e-21; PValue = 4.24e-24; mean CPM = 240.7; interferon regulatory factor 1" ID="ID_1222175408" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_1506343721" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1997742138" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_577159469" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_1061408953" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL6ST: 1.78-fold Up; FDR = 1.86e-08; PValue = 8.65e-10; mean CPM = 437.6; interleukin 6 signal transducer (gp130, oncostatin M receptor)" ID="ID_1208170651" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRDM1: 3.05-fold Up; FDR = 3.55e-08; PValue = 1.78e-09; mean CPM = 8.715; PR domain containing 1, with ZNF domain" ID="ID_85287714" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1196019456" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L1: 1.51-fold Up; FDR = 9.13e-07; PValue = 6.52e-08; mean CPM = 66.15; Bcl-2-like protein 1; Bcl-2-like protein 1 isoform 1; Uncharacterized protein" ID="ID_1346535286" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_103934467" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL6R: 3.84-fold Down; FDR = 6.68e-05; PValue = 7.89e-06; mean CPM = 4.840; interleukin 6 receptor" ID="ID_354807787" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAD: 1.36-fold Down; FDR = 0.000605; PValue = 9.52e-05; mean CPM = 48.46; BCL2-associated agonist of cell death" ID="ID_195911100" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS3: 1.69-fold Up; FDR = 0.000994; PValue = 0.000167; mean CPM = 37.76; suppressor of cytokine signaling 3" ID="ID_980889015" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYK2: 1.24-fold Down; FDR = 0.0142; PValue = 0.00354; mean CPM = 42.58; tyrosine kinase 2" ID="ID_1057564374" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC1: 1.25-fold Up; FDR = 0.0159; PValue = 0.00403; mean CPM = 27.51; histone deacetylase 1" ID="ID_949286530" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1894791011" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1651269984" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_572186994" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCOA1: 1.18-fold Up; FDR = 0.112; PValue = 0.04; mean CPM = 20.42; nuclear receptor coactivator 1" ID="ID_445000891" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_1702984408" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="A2M: 1.33-fold Up; FDR = 0.181; PValue = 0.0726; mean CPM = 750.0; alpha-2-macroglobulin" ID="ID_702858681" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_546140085" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_116222556" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_526966474" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_1838828708" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GAB1: 1.1-fold Up; FDR = 0.635; PValue = 0.356; mean CPM = 14.59; GRB2-associated binding protein 1" ID="ID_791103860" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCD: 1.06-fold Up; FDR = 0.696; PValue = 0.404; mean CPM = 37.45; protein kinase C, delta" ID="ID_98072375" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HCK: 1.3-fold Down; FDR = 0.797; PValue = 0.494; mean CPM = 0.9272; Uncharacterized protein" ID="ID_1714127018" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV1: 1.25-fold Down; FDR = 0.858; PValue = 0.572; mean CPM = 0.9515; vav 1 guanine nucleotide exchange factor" ID="ID_672590606" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1795010813" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB1: 1.04-fold Up; FDR = 0.88; PValue = 0.6; mean CPM = 30.80; Uncharacterized protein" ID="ID_1886439921" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_751069511" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_295660162" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREBBP: 1.01-fold Down; FDR = 0.993; PValue = 0.847; mean CPM = 137.7; CREB binding protein" ID="ID_1933258974" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_1691517191" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLK: No Change; FDR = 1; PValue = 0.97; mean CPM = 11.78; nemo-like kinase" ID="ID_1168671191" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AGT: 1.02-fold Down; FDR = 1; PValue = 0.996; mean CPM = 0.8004; angiotensinogen (serpin peptidase inhibitor, clade A, member 8)" ID="ID_1152424627" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRP: No Change; FDR = 1; PValue = 1; mean CPM = 0.7818; Uncharacterized protein" ID="ID_1758848776" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="General chemokine pathways: FDR = 1.43e-10, PValue = 1.59e-11" ID="ID_37703108" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CXCL10: 462-fold Up; FDR = 1.01e-21; PValue = 2.65e-24; mean CPM = 286.2; Macaca mulatta chemokine (C-X-C motif) ligand 10 (CXCL10), mRNA." ID="ID_811566858" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL11: 256-fold Up; FDR = 1e-19; PValue = 3.96e-22; mean CPM = 84.82; chemokine (C-X-C motif) ligand 11" ID="ID_227036040" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL9: 345-fold Up; FDR = 4.16e-19; PValue = 1.97e-21; mean CPM = 175.7; Macaca mulatta chemokine (C-X-C motif) ligand 9 (CXCL9), mRNA." ID="ID_1958459215" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT2: 2.67-fold Up; FDR = 8.02e-19; PValue = 4.03e-21; mean CPM = 185.6; signal transducer and activator of transcription 2, 113kDa" ID="ID_289240128" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_1020472358" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_575875305" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL2: 24.6-fold Up; FDR = 1.83e-15; PValue = 1.69e-17; mean CPM = 668.2; Macaca mulatta chemokine (C-C motif) ligand 2 (CCL2), mRNA." ID="ID_203091882" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG10: 2.27-fold Up; FDR = 1.24e-13; PValue = 1.66e-15; mean CPM = 24.29; guanine nucleotide binding protein (G protein), gamma 10" ID="ID_355702599" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC4: 7.09-fold Down; FDR = 1.82e-12; PValue = 3.1e-14; mean CPM = 6.421; SHC (Src homology 2 domain containing) family, member 4" ID="ID_1986500490" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CX3CL1: 6.16-fold Up; FDR = 5.13e-12; PValue = 1e-13; mean CPM = 14.86; chemokine (C-X3-C motif) ligand 1" ID="ID_1303971467" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_1838665312" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY6: 1.89-fold Down; FDR = 1.9e-10; PValue = 5.38e-12; mean CPM = 141.3; adenylate cyclase 6" ID="ID_1583241977" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL13: 12.3-fold Up; FDR = 4.33e-10; PValue = 1.35e-11; mean CPM = 3.824; chemokine (C-C motif) ligand 13" ID="ID_1296561249" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNB4: 2.14-fold Up; FDR = 2.52e-09; PValue = 9.35e-11; mean CPM = 33.45; guanine nucleotide binding protein (G protein), beta polypeptide 4" ID="ID_1468632623" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_314872824" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL7: 8.24-fold Up; FDR = 6.67e-09; PValue = 2.75e-10; mean CPM = 8.249; chemokine (C-C motif) ligand 7" ID="ID_621176452" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_278946615" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL16: 3.58-fold Up; FDR = 1.19e-07; PValue = 6.74e-09; mean CPM = 6.893; chemokine (C-X-C motif) ligand 16" ID="ID_1807449194" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2B: 3.54-fold Up; FDR = 1.24e-07; PValue = 7.07e-09; mean CPM = 5.971; PTK2B protein tyrosine kinase 2 beta" ID="ID_519277272" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1B: 1.55-fold Up; FDR = 2.39e-07; PValue = 1.46e-08; mean CPM = 135.3; Ras-related protein Rap-1b; Ras-related protein Rap-1b isoform 1; Uncharacterized protein" ID="ID_408195784" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL5: 6.74-fold Up; FDR = 2.65e-07; PValue = 1.64e-08; mean CPM = 30.35; chemokine (C-C motif) ligand 5" ID="ID_1982068346" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG11: 1.65-fold Up; FDR = 2.71e-07; PValue = 1.68e-08; mean CPM = 86.60; guanine nucleotide binding protein (G protein), gamma 11" ID="ID_1704741238" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1362509018" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCB1: 1.71-fold Up; FDR = 1.31e-06; PValue = 9.73e-08; mean CPM = 34.36; phospholipase C, beta 1 (phosphoinositide-specific)" ID="ID_862249432" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_38095261" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_1915555672" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_504601606" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADRBK1: 1.5-fold Down; FDR = 3.36e-06; PValue = 2.76e-07; mean CPM = 46.25; adrenergic, beta, receptor kinase 1" ID="ID_1621458499" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_623323118" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL11: 6.86-fold Up; FDR = 2.69e-05; PValue = 2.82e-06; mean CPM = 4.204; chemokine (C-C motif) ligand 11" ID="ID_416927198" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAI1: 1.47-fold Up; FDR = 5.94e-05; PValue = 6.9e-06; mean CPM = 97.19; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1" ID="ID_1351561041" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNB3: 1.91-fold Down; FDR = 0.000162; PValue = 2.14e-05; mean CPM = 7.202; guanine nucleotide binding protein (G protein), beta polypeptide 3" ID="ID_737409044" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACA: 1.36-fold Down; FDR = 0.000167; PValue = 2.22e-05; mean CPM = 37.75; protein kinase, cAMP-dependent, catalytic, alpha" ID="ID_1901636786" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCAR1: 1.36-fold Up; FDR = 0.000193; PValue = 2.61e-05; mean CPM = 210.4; breast cancer anti-estrogen resistance 1" ID="ID_1042832235" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCB4: 1.75-fold Down; FDR = 0.00025; PValue = 3.52e-05; mean CPM = 6.730; phospholipase C, beta 4" ID="ID_1124579660" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASGRP2: 2.4-fold Up; FDR = 0.000359; PValue = 5.28e-05; mean CPM = 5.834; Uncharacterized protein" ID="ID_108081542" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PREX1: 1.34-fold Down; FDR = 0.000592; PValue = 9.28e-05; mean CPM = 89.02; phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1" ID="ID_858954993" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK3: 2.31-fold Up; FDR = 0.00186; PValue = 0.000342; mean CPM = 2.154; Janus kinase 3" ID="ID_624219237" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCR4: 4.65-fold Down; FDR = 0.00226; PValue = 0.000426; mean CPM = 2.073; chemokine (C-X-C motif) receptor 4" ID="ID_1684312311" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHOA: 1.28-fold Down; FDR = 0.00295; PValue = 0.000575; mean CPM = 277.8; ras homolog gene family, member A" ID="ID_647494938" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKX: 1.31-fold Down; FDR = 0.00331; PValue = 0.000658; mean CPM = 24.94; protein kinase, X-linked" ID="ID_330917035" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1B: 1.43-fold Up; FDR = 0.00346; PValue = 0.000693; mean CPM = 12.81; RAP1B, member of RAS oncogene family" ID="ID_1924212217" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG12: 1.31-fold Up; FDR = 0.00387; PValue = 0.000792; mean CPM = 24.97; guanine nucleotide binding protein (G protein), gamma 12" ID="ID_999104682" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL3: 3.28-fold Up; FDR = 0.00459; PValue = 0.000963; mean CPM = 50.55; chemokine (C-X-C motif) ligand 3" ID="ID_713777284" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV3: 1.82-fold Down; FDR = 0.00463; PValue = 0.000973; mean CPM = 7.044; vav 3 guanine nucleotide exchange factor" ID="ID_376769614" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAI3: 1.26-fold Up; FDR = 0.00487; PValue = 0.00103; mean CPM = 113.8; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3" ID="ID_1779515764" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1946649899" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR9: 3.89-fold Down; FDR = 0.00547; PValue = 0.00117; mean CPM = 0.9346; chemokine (C-C motif) receptor 9" ID="ID_997593154" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL1: 2.18-fold Up; FDR = 0.00609; PValue = 0.00133; mean CPM = 45.92; chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)" ID="ID_1492893758" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL8: 3.3-fold Up; FDR = 0.00609; PValue = 0.00133; mean CPM = 1.313; chemokine (C-C motif) ligand 8" ID="ID_18392879" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WASL: 1.26-fold Up; FDR = 0.00781; PValue = 0.00177; mean CPM = 33.90; Wiskott-Aldrich syndrome-like" ID="ID_1461113547" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PF4V1: 2.28-fold Down; FDR = 0.00877; PValue = 0.00202; mean CPM = 3.258; platelet factor 4 variant 1" ID="ID_673776325" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY9: 1.32-fold Down; FDR = 0.00986; PValue = 0.00231; mean CPM = 84.04; adenylate cyclase 9" ID="ID_438469895" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL20: 2.09-fold Up; FDR = 0.0108; PValue = 0.00256; mean CPM = 60.21; Macaca mulatta chemokine (C-C motif) ligand 20 (CCL20), mRNA." ID="ID_1938069054" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCZ: 1.51-fold Up; FDR = 0.0152; PValue = 0.00381; mean CPM = 10.46; protein kinase C, zeta" ID="ID_1755725520" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRK4: 1.55-fold Down; FDR = 0.0188; PValue = 0.0049; mean CPM = 5.871; G protein-coupled receptor kinase 4" ID="ID_1921974497" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1655440784" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL8: 2.33-fold Up; FDR = 0.0209; PValue = 0.00552; mean CPM = 2326; interleukin 8" ID="ID_971403187" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DOCK2: 1.4-fold Up; FDR = 0.0216; PValue = 0.00573; mean CPM = 37.89; dedicator of cytokinesis 2" ID="ID_1504174868" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1577790456" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC2: 2.96-fold Up; FDR = 0.0309; PValue = 0.00872; mean CPM = 0.9737; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)" ID="ID_223029011" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL18: 3.2-fold Down; FDR = 0.0322; PValue = 0.00915; mean CPM = 0.9111; chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)" ID="ID_664302559" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR7: 1.48-fold Down; FDR = 0.0357; PValue = 0.0103; mean CPM = 13.37; chemokine (C-C motif) receptor 7" ID="ID_1705629144" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_433600336" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KRAS: 1.35-fold Down; FDR = 0.0401; PValue = 0.0119; mean CPM = 13.10; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog" ID="ID_1249585717" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY5: 2.17-fold Down; FDR = 0.042; PValue = 0.0125; mean CPM = 1.219; adenylate cyclase 5" ID="ID_1799225496" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY7: 1.24-fold Down; FDR = 0.0434; PValue = 0.013; mean CPM = 157.2; adenylate cyclase 7" ID="ID_1587293238" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCB2: 3.68-fold Down; FDR = 0.0481; PValue = 0.0147; mean CPM = 1.557; Uncharacterized protein" ID="ID_209952289" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NRAS: 1.2-fold Down; FDR = 0.0546; PValue = 0.017; mean CPM = 32.39; neuroblastoma RAS viral (v-ras) oncogene homolog" ID="ID_1850333274" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL28: 2.67-fold Up; FDR = 0.0616; PValue = 0.0197; mean CPM = 1.020; chemokine (C-C motif) ligand 28" ID="ID_754420162" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL3: 2.04-fold Down; FDR = 0.067; PValue = 0.0218; mean CPM = 3.575; chemokine (C-C motif) ligand 3" ID="ID_841479210" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_1301299098" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TIAM1: 1.23-fold Up; FDR = 0.0747; PValue = 0.0248; mean CPM = 38.38; T-cell lymphoma invasion and metastasis 1" ID="ID_1277444342" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCR5: 2.19-fold Down; FDR = 0.0766; PValue = 0.0256; mean CPM = 1.341; chemokine (C-X-C motif) receptor 5" ID="ID_555438007" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1A: 1.17-fold Up; FDR = 0.0888; PValue = 0.0304; mean CPM = 37.16; RAP1A, member of RAS oncogene family" ID="ID_1950639109" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3A: 1.18-fold Down; FDR = 0.097; PValue = 0.0338; mean CPM = 25.14; Glycogen synthase kinase-3 alpha; Uncharacterized protein" ID="ID_1724789732" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS2: 1.17-fold Up; FDR = 0.1; PValue = 0.0353; mean CPM = 31.79; son of sevenless homolog 2 (Drosophila)" ID="ID_1973606225" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARRB1: 1.35-fold Down; FDR = 0.107; PValue = 0.0382; mean CPM = 4.106; arrestin, beta 1" ID="ID_15619317" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_1058617801" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG2: 1.64-fold Up; FDR = 0.117; PValue = 0.0421; mean CPM = 2.320; guanine nucleotide binding protein (G protein), gamma 2" ID="ID_1019284743" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAI2: 1.15-fold Down; FDR = 0.134; PValue = 0.0501; mean CPM = 356.3; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2" ID="ID_817197109" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_1365520115" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG3: 1.6-fold Down; FDR = 0.155; PValue = 0.0601; mean CPM = 1.706; guanine nucleotide binding protein (G protein), gamma 3" ID="ID_1439410231" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ROCK2: 1.14-fold Up; FDR = 0.166; PValue = 0.065; mean CPM = 247.7; Rho-associated, coiled-coil containing protein kinase 2" ID="ID_1685831621" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC2: 1.34-fold Down; FDR = 0.191; PValue = 0.0774; mean CPM = 7.313; SHC (Src homology 2 domain containing) transforming protein 2" ID="ID_287203016" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_701352794" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL6: 1.5-fold Down; FDR = 0.2; PValue = 0.082; mean CPM = 258.8; chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)" ID="ID_1259318915" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_692620885" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BRAF: 1.14-fold Down; FDR = 0.228; PValue = 0.0964; mean CPM = 24.98; v-raf murine sarcoma viral oncogene homolog B1" ID="ID_1811261613" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_1270455203" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY4: 1.24-fold Up; FDR = 0.328; PValue = 0.151; mean CPM = 8.390; adenylate cyclase 4" ID="ID_465944462" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_237658001" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ELMO1: 1.82-fold Down; FDR = 0.348; PValue = 0.163; mean CPM = 2.504; engulfment and cell motility 1" ID="ID_1770733417" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG7: 1.75-fold Down; FDR = 0.366; PValue = 0.174; mean CPM = 0.9647; guanine nucleotide binding protein (G protein), gamma 7" ID="ID_390851289" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRKL: 1.11-fold Up; FDR = 0.371; PValue = 0.176; mean CPM = 34.10; v-crk sarcoma virus CT10 oncogene homolog (avian)-like" ID="ID_456744241" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_897346421" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2: 1.1-fold Up; FDR = 0.394; PValue = 0.191; mean CPM = 102.5; PTK2 protein tyrosine kinase 2" ID="ID_549064775" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL14: 1.14-fold Up; FDR = 0.405; PValue = 0.197; mean CPM = 133.7; Uncharacterized protein" ID="ID_1201648383" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL26: 1.74-fold Down; FDR = 0.423; PValue = 0.208; mean CPM = 0.8756; chemokine (C-C motif) ligand 26" ID="ID_1068016534" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_683643474" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR5: 1.56-fold Down; FDR = 0.487; PValue = 0.249; mean CPM = 1.064; chemokine (C-C motif) receptor 5" ID="ID_417392147" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL12: 1.27-fold Down; FDR = 0.488; PValue = 0.251; mean CPM = 4.383; chemokine (C-X-C motif) ligand 12" ID="ID_1543058880" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGR: 1.63-fold Up; FDR = 0.516; PValue = 0.269; mean CPM = 1.191; Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog" ID="ID_644568958" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG4: 1.65-fold Down; FDR = 0.524; PValue = 0.275; mean CPM = 0.8771; guanine nucleotide binding protein (G protein), gamma 4" ID="ID_134486407" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_209521071" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOXO3: 1.08-fold Down; FDR = 0.55; PValue = 0.294; mean CPM = 48.45; forkhead box O3" ID="ID_168001526" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNB1: 1.08-fold Down; FDR = 0.565; PValue = 0.305; mean CPM = 299.4; guanine nucleotide binding protein (G protein), beta polypeptide 1" ID="ID_1984118582" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PARD3: 1.07-fold Up; FDR = 0.581; PValue = 0.316; mean CPM = 129.4; par-3 partitioning defective 3 homolog (C. elegans)" ID="ID_141128040" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC3: 1.37-fold Down; FDR = 0.584; PValue = 0.318; mean CPM = 1.193; SHC-transforming protein 3; Uncharacterized protein" ID="ID_567815434" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDC42: 1.07-fold Down; FDR = 0.608; PValue = 0.335; mean CPM = 91.67; cell division cycle 42" ID="ID_441950178" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNGT2: 1.9-fold Up; FDR = 0.613; PValue = 0.339; mean CPM = 0.8227; guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2" ID="ID_557294170" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000001259: 1.31-fold Down; FDR = 0.663; PValue = 0.378; mean CPM = 3.829; Uncharacterized protein" ID="ID_1314949404" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSK: 1.06-fold Down; FDR = 0.673; PValue = 0.386; mean CPM = 45.36; c-src tyrosine kinase" ID="ID_1476787480" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CX3CR1: 2.01-fold Up; FDR = 0.678; PValue = 0.389; mean CPM = 0.8149; chemokine (C-X3-C motif) receptor 1" ID="ID_1957013699" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNB2: 1.06-fold Down; FDR = 0.685; PValue = 0.395; mean CPM = 129.1; guanine nucleotide binding protein (G protein), beta polypeptide 2" ID="ID_1892865184" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCD: 1.06-fold Up; FDR = 0.696; PValue = 0.404; mean CPM = 37.45; protein kinase C, delta" ID="ID_739059721" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADRBK2: 1.11-fold Down; FDR = 0.715; PValue = 0.419; mean CPM = 8.977; adrenergic, beta, receptor kinase 2" ID="ID_1312566100" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCB: 1.86-fold Up; FDR = 0.727; PValue = 0.43; mean CPM = 0.8705; protein kinase C, beta" ID="ID_1559383320" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG13: 1.67-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8104; guanine nucleotide binding protein (G protein), gamma 13" ID="ID_916713438" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WAS: 1.37-fold Down; FDR = 0.771; PValue = 0.469; mean CPM = 0.9085; Wiskott-Aldrich syndrome" ID="ID_1820053952" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL1: 1.56-fold Up; FDR = 0.772; PValue = 0.47; mean CPM = 0.8202; chemokine (C-C motif) ligand 1" ID="ID_1542750487" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRK: 1.05-fold Up; FDR = 0.791; PValue = 0.488; mean CPM = 59.92; v-crk sarcoma virus CT10 oncogene homolog (avian)" ID="ID_1932915195" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACG: 1.51-fold Down; FDR = 0.795; PValue = 0.491; mean CPM = 0.8026; protein kinase, cAMP-dependent, catalytic, gamma" ID="ID_1276627252" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HCK: 1.3-fold Down; FDR = 0.797; PValue = 0.494; mean CPM = 0.9272; Uncharacterized protein" ID="ID_257020984" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR6: 1.51-fold Down; FDR = 0.807; PValue = 0.504; mean CPM = 0.8112; Macaca mulatta chemokine (C-C motif) receptor 6 (CCR6), mRNA." ID="ID_1787252618" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL27: 1.17-fold Up; FDR = 0.817; PValue = 0.515; mean CPM = 1.645; chemokine (C-C motif) ligand 27" ID="ID_1650979651" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRK5: 1.09-fold Up; FDR = 0.82; PValue = 0.519; mean CPM = 11.78; G protein-coupled receptor kinase 5" ID="ID_1177222078" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR2: 1.51-fold Up; FDR = 0.823; PValue = 0.523; mean CPM = 0.8333; chemokine (C-C motif) receptor 2" ID="ID_1891038462" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR4: 1.74-fold Up; FDR = 0.831; PValue = 0.533; mean CPM = 0.8536; chemokine (C-C motif) receptor 4" ID="ID_1801263597" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XCL1: 1.39-fold Up; FDR = 0.838; PValue = 0.544; mean CPM = 0.8038; chemokine (C motif) ligand 1" ID="ID_1143973107" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_699891594" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV1: 1.25-fold Down; FDR = 0.858; PValue = 0.572; mean CPM = 0.9515; vav 1 guanine nucleotide exchange factor" ID="ID_1243896453" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY2: 1.18-fold Down; FDR = 0.864; PValue = 0.58; mean CPM = 1.755; adenylate cyclase 2 (brain)" ID="ID_365056806" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL16: 1.27-fold Up; FDR = 0.865; PValue = 0.581; mean CPM = 0.7999; chemokine (C-C motif) ligand 16" ID="ID_1095519389" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY8: 1.28-fold Up; FDR = 0.891; PValue = 0.614; mean CPM = 0.8757; adenylate cyclase 8 (brain)" ID="ID_1848616622" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XCL1: 1.24-fold Down; FDR = 0.899; PValue = 0.635; mean CPM = 0.7954; Macaca mulatta chemokine (C motif) ligand 1 (XCL1), mRNA." ID="ID_346975264" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XCL1: 1.24-fold Down; FDR = 0.899; PValue = 0.635; mean CPM = 0.7954; Macaca mulatta chemokine (C motif) ligand 1 (XCL1), mRNA." ID="ID_720835189" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000021684: 1.44-fold Up; FDR = 0.903; PValue = 0.662; mean CPM = 0.8513; Uncharacterized protein" ID="ID_1613646631" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR3: 1.43-fold Up; FDR = 0.906; PValue = 0.665; mean CPM = 0.8397; chemokine (C-C motif) receptor 3" ID="ID_1694319174" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY1: 1.13-fold Down; FDR = 0.908; PValue = 0.682; mean CPM = 1.243; adenylate cyclase 1 (brain)" ID="ID_615550055" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL14: 1.15-fold Up; FDR = 0.909; PValue = 0.69; mean CPM = 0.7938; chemokine (C-C motif) ligand 14" ID="ID_25680730" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACB: 1.03-fold Up; FDR = 0.911; PValue = 0.694; mean CPM = 30.10; protein kinase, cAMP-dependent, catalytic, beta" ID="ID_1078745430" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK1: 1.03-fold Down; FDR = 0.911; PValue = 0.705; mean CPM = 18.65; p21 protein (Cdc42/Rac)-activated kinase 1" ID="ID_817641982" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR1: 1.24-fold Up; FDR = 0.915; PValue = 0.714; mean CPM = 0.8590; Macaca mulatta chemokine (C-C motif) receptor 1 (CCR1), mRNA." ID="ID_475453740" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_1742147592" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG5: 1.02-fold Down; FDR = 0.952; PValue = 0.781; mean CPM = 21.93; guanine nucleotide binding protein (G protein), gamma 5" ID="ID_779676986" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_516642766" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XCR1: 1.09-fold Up; FDR = 0.971; PValue = 0.812; mean CPM = 0.8071; chemokine (C motif) receptor 1" ID="ID_398483533" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL21: 1.09-fold Down; FDR = 0.972; PValue = 0.813; mean CPM = 1.083; chemokine (C-C motif) ligand 21" ID="ID_1610523249" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRK1: 1.21-fold Up; FDR = 0.987; PValue = 0.837; mean CPM = 0.8126; G protein-coupled receptor kinase 1" ID="ID_1091932896" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG8: 1.11-fold Down; FDR = 0.989; PValue = 0.84; mean CPM = 0.8494; guanine nucleotide binding protein (G protein), gamma 8" ID="ID_1038467184" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR8: 1.15-fold Down; FDR = 0.999; PValue = 0.857; mean CPM = 0.8181; chemokine (C-C motif) receptor 8" ID="ID_656980395" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY3: 1.01-fold Up; FDR = 1; PValue = 0.871; mean CPM = 34.92; adenylate cyclase 3" ID="ID_228575032" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNGT1: 1.05-fold Up; FDR = 1; PValue = 0.871; mean CPM = 0.8362; guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1" ID="ID_868029813" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITK: 1.07-fold Up; FDR = 1; PValue = 0.871; mean CPM = 0.9033; IL2-inducible T-cell kinase" ID="ID_147736963" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL25: 1.05-fold Down; FDR = 1; PValue = 0.872; mean CPM = 1.770; chemokine (C-C motif) ligand 25" ID="ID_2230409" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL22: 1.13-fold Down; FDR = 1; PValue = 0.872; mean CPM = 0.8179; chemokine (C-C motif) ligand 22" ID="ID_1523967660" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNB5: 1.04-fold Down; FDR = 1; PValue = 0.881; mean CPM = 1.533; guanine nucleotide binding protein (G protein), beta 5" ID="ID_884583016" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR10: 1.01-fold Down; FDR = 1; PValue = 0.929; mean CPM = 4.275; chemokine (C-C motif) receptor 10" ID="ID_1233161792" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCR2: 1.14-fold Up; FDR = 1; PValue = 0.929; mean CPM = 0.8384; chemokine (C-X-C motif) receptor 2" ID="ID_6701268" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCR3: 1.03-fold Up; FDR = 1; PValue = 0.943; mean CPM = 0.9843; chemokine (C-X-C motif) receptor 3" ID="ID_1735178772" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPBP: 1.16-fold Up; FDR = 1; PValue = 0.95; mean CPM = 0.8406; pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)" ID="ID_110187513" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_979311442" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL23: 1.03-fold Down; FDR = 1; PValue = 0.963; mean CPM = 0.9423; Macaca mulatta chemokine (C-C motif) ligand 23 (CCL23), mRNA." ID="ID_263361306" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV2: No Change; FDR = 1; PValue = 0.976; mean CPM = 25.65; vav 2 guanine nucleotide exchange factor" ID="ID_1789087267" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRK7: 1.04-fold Down; FDR = 1; PValue = 0.982; mean CPM = 0.8188; G protein-coupled receptor kinase 7" ID="ID_1901615044" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL17: 1.01-fold Up; FDR = 1; PValue = 0.993; mean CPM = 0.8083; Macaca mulatta chemokine (C-C motif) ligand 17 (CCL17), mRNA." ID="ID_1342694290" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL24: 1.01-fold Up; FDR = 1; PValue = 0.999; mean CPM = 0.8072; Uncharacterized protein" ID="ID_1325100841" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL13: No Change; FDR = 1; PValue = 1; mean CPM = 0.7851; chemokine (C-X-C motif) ligand 13" ID="ID_1759532014" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCR1: No Change; FDR = 1; PValue = 1; mean CPM = 0.7827; chemokine (C-X-C motif) receptor 1" ID="ID_924581610" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PF4: 1.04-fold Up; FDR = 1; PValue = 1; mean CPM = 0.8136; platelet factor 4" ID="ID_273667654" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="MTor: FDR = 1.55e-10, PValue = 2.13e-11" ID="ID_1670381736" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TLR2: 8.94-fold Up; FDR = 6.97e-23; PValue = 1.25e-25; mean CPM = 18.41; toll-like receptor 2" ID="ID_938163435" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF1: 18.6-fold Up; FDR = 1.53e-21; PValue = 4.24e-24; mean CPM = 240.7; interferon regulatory factor 1" ID="ID_724645210" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR3: 10.3-fold Up; FDR = 1.95e-21; PValue = 5.6e-24; mean CPM = 35.70; toll-like receptor 3" ID="ID_1080907527" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF7: 14.8-fold Up; FDR = 7.66e-18; PValue = 4.82e-20; mean CPM = 11.54; Macaca mulatta interferon regulatory factor 7 (IRF7), mRNA." ID="ID_1559012189" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_1333013993" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR4: 3.45-fold Up; FDR = 3.1e-09; PValue = 1.19e-10; mean CPM = 7.456; Macaca mulatta toll-like receptor 4 (TLR4), mRNA." ID="ID_835319833" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1B: 1.64-fold Up; FDR = 1.22e-08; PValue = 5.39e-10; mean CPM = 32.96; Cyclin-dependent kinase inhibitor 1B; Uncharacterized protein" ID="ID_1937878222" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INSR: 1.93-fold Down; FDR = 1.24e-08; PValue = 5.48e-10; mean CPM = 118.3; insulin receptor" ID="ID_698788348" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_672437724" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_706251475" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_925670626" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1: 5.76-fold Down; FDR = 6.73e-06; PValue = 6.04e-07; mean CPM = 1.536; insulin-like growth factor 1 (somatomedin C)" ID="ID_428957790" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TSC2: 1.44-fold Down; FDR = 1e-05; PValue = 9.42e-07; mean CPM = 124.0; tuberous sclerosis 2" ID="ID_690678567" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPTOR: 1.4-fold Down; FDR = 2.58e-05; PValue = 2.69e-06; mean CPM = 53.57; regulatory associated protein of MTOR, complex 1" ID="ID_178011921" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KLF2: 1.79-fold Down; FDR = 3.43e-05; PValue = 3.72e-06; mean CPM = 18.91; Uncharacterized protein" ID="ID_1277446955" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB2: 1.38-fold Down; FDR = 4.66e-05; PValue = 5.24e-06; mean CPM = 61.90; ribosomal protein S6 kinase, 70kDa, polypeptide 2" ID="ID_502351380" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_1179693028" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KIAA0652: 1.35-fold Up; FDR = 0.00021; PValue = 2.87e-05; mean CPM = 44.45; KIAA0652" ID="ID_343131063" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RB1CC1: 1.34-fold Up; FDR = 0.000258; PValue = 3.64e-05; mean CPM = 132.0; Uncharacterized protein" ID="ID_1176092340" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTOR: 1.3-fold Down; FDR = 0.00117; PValue = 0.000201; mean CPM = 107.5; mechanistic target of rapamycin (serine/threonine kinase)" ID="ID_1652568272" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF4EBP2: 1.38-fold Down; FDR = 0.00161; PValue = 0.00029; mean CPM = 14.84; eukaryotic translation initiation factor 4E binding protein 2" ID="ID_1605216934" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1S1: 1.31-fold Down; FDR = 0.00202; PValue = 0.000375; mean CPM = 35.32; AKT1 substrate 1 (proline-rich)" ID="ID_1519385811" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SGK1: 1.36-fold Down; FDR = 0.0048; PValue = 0.00101; mean CPM = 395.0; Uncharacterized protein" ID="ID_1986803028" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR5: 1.86-fold Down; FDR = 0.00878; PValue = 0.00203; mean CPM = 3.008; toll-like receptor 5" ID="ID_1410360962" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12A: 2.09-fold Up; FDR = 0.00924; PValue = 0.00215; mean CPM = 2.872; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)" ID="ID_277483112" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ULK1: 1.34-fold Down; FDR = 0.0121; PValue = 0.00293; mean CPM = 33.52; unc-51-like kinase 1 (C. elegans)" ID="ID_1393083669" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1542001462" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF4EBP2: 1.75-fold Down; FDR = 0.0339; PValue = 0.00972; mean CPM = 2.255; Eukaryotic translation initiation factor 4E-binding protein 2; Uncharacterized protein" ID="ID_820322957" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR7: 1.48-fold Down; FDR = 0.0357; PValue = 0.0103; mean CPM = 13.37; chemokine (C-C motif) receptor 7" ID="ID_1719880051" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_992975063" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TSC1: 1.19-fold Down; FDR = 0.0564; PValue = 0.0177; mean CPM = 38.34; tuberous sclerosis 1" ID="ID_505943634" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF4EBP1: 1.23-fold Up; FDR = 0.0729; PValue = 0.0241; mean CPM = 40.55; eukaryotic translation initiation factor 4E binding protein 1" ID="ID_6616754" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3A: 1.18-fold Down; FDR = 0.097; PValue = 0.0338; mean CPM = 25.14; Glycogen synthase kinase-3 alpha; Uncharacterized protein" ID="ID_928618687" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_1305695242" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTEN: 1.14-fold Up; FDR = 0.166; PValue = 0.065; mean CPM = 89.60; phosphatase and tensin homolog" ID="ID_647895454" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHEB: 1.13-fold Up; FDR = 0.193; PValue = 0.0785; mean CPM = 118.9; Ras homolog enriched in brain" ID="ID_1706328628" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT3A: 2.28-fold Down; FDR = 0.2; PValue = 0.0823; mean CPM = 0.8811; wingless-type MMTV integration site family, member 3A" ID="ID_776992420" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_1445246208" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKAB1: 1.12-fold Up; FDR = 0.3; PValue = 0.136; mean CPM = 30.19; protein kinase, AMP-activated, beta 1 non-catalytic subunit" ID="ID_1478415113" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_156080365" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL23A: 1.39-fold Up; FDR = 0.348; PValue = 0.163; mean CPM = 4.542; interleukin 23, alpha subunit p19" ID="ID_515821103" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPKAP1: 1.1-fold Up; FDR = 0.373; PValue = 0.177; mean CPM = 55.89; mitogen-activated protein kinase associated protein 1" ID="ID_773273298" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1015943187" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_93304567" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNB1: 1.79-fold Up; FDR = 0.731; PValue = 0.433; mean CPM = 0.8526; interferon, beta 1, fibroblast" ID="ID_857155066" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR6: 1.07-fold Down; FDR = 0.84; PValue = 0.546; mean CPM = 7.909; toll-like receptor 6" ID="ID_346832852" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FKBP1A: 1.04-fold Down; FDR = 0.851; PValue = 0.562; mean CPM = 209.1; Peptidyl-prolyl cis-trans isomerase" ID="ID_1756732361" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR7: 1.37-fold Down; FDR = 0.878; PValue = 0.597; mean CPM = 0.8402; toll-like receptor 7" ID="ID_42850473" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB1: 1.04-fold Up; FDR = 0.88; PValue = 0.6; mean CPM = 30.80; Uncharacterized protein" ID="ID_1582598255" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12B: 1.07-fold Up; FDR = 0.983; PValue = 0.831; mean CPM = 0.8197; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)" ID="ID_1963092414" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR9: 1.01-fold Down; FDR = 1; PValue = 0.859; mean CPM = 21.45; Macaca mulatta toll-like receptor 9 (TLR9), mRNA." ID="ID_1753226694" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STK11: 1.01-fold Up; FDR = 1; PValue = 0.918; mean CPM = 47.98; serine/threonine kinase 11" ID="ID_440800155" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C12orf44: 1.01-fold Up; FDR = 1; PValue = 0.938; mean CPM = 59.62; Autophagy-related protein 101" ID="ID_1549173637" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR1: 1.02-fold Up; FDR = 1; PValue = 0.945; mean CPM = 1.221; toll-like receptor 1" ID="ID_679366473" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL10: 1.21-fold Down; FDR = 1; PValue = 0.964; mean CPM = 0.8614; interleukin 10" ID="ID_1009590518" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SELL: 1.04-fold Up; FDR = 1; PValue = 0.995; mean CPM = 0.8177; Macaca mulatta selectin L (SELL), mRNA." ID="ID_1555219268" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="T cell subtype specific molecules: FDR = 1.55e-10, PValue = 2.6e-11" ID="ID_87753292" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1330895698" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB3: 4.82-fold Down; FDR = 1.82e-12; PValue = 3.09e-14; mean CPM = 9.911; transforming growth factor, beta 3" ID="ID_1319076982" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_888382772" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_548629925" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL18R1: 3.18-fold Down; FDR = 5.89e-06; PValue = 5.19e-07; mean CPM = 3.445; interleukin 18 receptor 1" ID="ID_1195188392" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RORA: 1.67-fold Up; FDR = 1.88e-05; PValue = 1.9e-06; mean CPM = 25.24; RAR-related orphan receptor A" ID="ID_1632557207" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT4: 1.79-fold Up; FDR = 2.3e-05; PValue = 2.36e-06; mean CPM = 26.79; signal transducer and activator of transcription 4" ID="ID_846872298" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1R1: 1.6-fold Up; FDR = 3.35e-05; PValue = 3.61e-06; mean CPM = 123.7; interleukin 1 receptor, type I" ID="ID_1650845204" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40: 2.76-fold Up; FDR = 0.00039; PValue = 5.79e-05; mean CPM = 9.139; CD40 molecule, TNF receptor superfamily member 5" ID="ID_1684710514" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GATA3: 2.81-fold Up; FDR = 0.000734; PValue = 0.000119; mean CPM = 2.229; GATA binding protein 3" ID="ID_858409474" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR1: 1.31-fold Up; FDR = 0.00151; PValue = 0.000268; mean CPM = 37.77; interferon gamma receptor 1" ID="ID_910198611" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCR4: 4.65-fold Down; FDR = 0.00226; PValue = 0.000426; mean CPM = 2.073; chemokine (C-X-C motif) receptor 4" ID="ID_1324288174" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12A: 2.09-fold Up; FDR = 0.00924; PValue = 0.00215; mean CPM = 2.872; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)" ID="ID_1968022848" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL18: 1.5-fold Down; FDR = 0.00981; PValue = 0.0023; mean CPM = 6.489; interleukin 18 (interferon-gamma-inducing factor)" ID="ID_46390517" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSF2: 2.96-fold Down; FDR = 0.0174; PValue = 0.00447; mean CPM = 73.98; colony stimulating factor 2 (granulocyte-macrophage)" ID="ID_323382752" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR2: 1.23-fold Up; FDR = 0.0258; PValue = 0.00707; mean CPM = 46.52; interferon gamma receptor 2 (interferon gamma transducer 1)" ID="ID_1890439468" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR7: 1.48-fold Down; FDR = 0.0357; PValue = 0.0103; mean CPM = 13.37; chemokine (C-C motif) receptor 7" ID="ID_1864075436" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF11: 1.8-fold Up; FDR = 0.039; PValue = 0.0115; mean CPM = 2.535; tumor necrosis factor (ligand) superfamily, member 11" ID="ID_461691564" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL3: 2.04-fold Down; FDR = 0.067; PValue = 0.0218; mean CPM = 3.575; chemokine (C-C motif) ligand 3" ID="ID_444758338" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT6: 1.18-fold Up; FDR = 0.0727; PValue = 0.024; mean CPM = 217.5; signal transducer and activator of transcription 6, interleukin-4 induced" ID="ID_994724642" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12RB2: 1.42-fold Down; FDR = 0.299; PValue = 0.135; mean CPM = 1.728; interleukin 12 receptor, beta 2" ID="ID_124926380" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR5: 1.56-fold Down; FDR = 0.487; PValue = 0.249; mean CPM = 1.064; chemokine (C-C motif) receptor 5" ID="ID_93876954" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF11A: 1.4-fold Down; FDR = 0.676; PValue = 0.388; mean CPM = 0.9723; tumor necrosis factor receptor superfamily, member 11a, NFKB activator" ID="ID_1857771461" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12RB1: 1.39-fold Up; FDR = 0.703; PValue = 0.41; mean CPM = 0.9665; interleukin 12 receptor, beta 1" ID="ID_1442899017" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLX: 1.14-fold Up; FDR = 0.737; PValue = 0.438; mean CPM = 7.730; Uncharacterized protein" ID="ID_33022328" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF4: 1.36-fold Down; FDR = 0.743; PValue = 0.444; mean CPM = 0.8892; tumor necrosis factor receptor superfamily, member 4" ID="ID_1992799062" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17RB: 1.24-fold Down; FDR = 0.752; PValue = 0.452; mean CPM = 1.299; interleukin 17 receptor B" ID="ID_1111970296" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL4R: 1.05-fold Down; FDR = 0.803; PValue = 0.499; mean CPM = 193.5; interleukin 4 receptor" ID="ID_734856466" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD4: 1.27-fold Up; FDR = 0.807; PValue = 0.503; mean CPM = 1.122; CD4 molecule" ID="ID_1339168723" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR6: 1.51-fold Down; FDR = 0.807; PValue = 0.504; mean CPM = 0.8112; Macaca mulatta chemokine (C-C motif) receptor 6 (CCR6), mRNA." ID="ID_376470226" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR4: 1.74-fold Up; FDR = 0.831; PValue = 0.533; mean CPM = 0.8536; chemokine (C-C motif) receptor 4" ID="ID_192748466" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DRB: 1.28-fold Up; FDR = 0.898; PValue = 0.624; mean CPM = 0.8112; MHC class II antigen; Uncharacterized protein" ID="ID_550416759" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_805311432" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL25: 1.24-fold Down; FDR = 0.899; PValue = 0.631; mean CPM = 0.7976; interleukin 25" ID="ID_934613981" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB2: 1.05-fold Down; FDR = 0.903; PValue = 0.655; mean CPM = 110.8; transforming growth factor, beta 2" ID="ID_606665944" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR3: 1.43-fold Up; FDR = 0.906; PValue = 0.665; mean CPM = 0.8397; chemokine (C-C motif) receptor 3" ID="ID_278331488" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17A: 1.12-fold Up; FDR = 0.911; PValue = 0.706; mean CPM = 0.7895; interleukin 17A" ID="ID_1675696238" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR1: 1.24-fold Up; FDR = 0.915; PValue = 0.714; mean CPM = 0.8590; Macaca mulatta chemokine (C-C motif) receptor 1 (CCR1), mRNA." ID="ID_1726312319" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL22: 1.33-fold Down; FDR = 0.928; PValue = 0.735; mean CPM = 0.8193; interleukin 22" ID="ID_1032118197" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICOS: 1.19-fold Up; FDR = 0.931; PValue = 0.741; mean CPM = 0.8158; Uncharacterized protein" ID="ID_981252328" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL4: 1.27-fold Down; FDR = 0.933; PValue = 0.745; mean CPM = 0.8077; interleukin 4" ID="ID_1949129983" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB1: 1.02-fold Down; FDR = 0.936; PValue = 0.749; mean CPM = 62.61; transforming growth factor, beta 1" ID="ID_1739706972" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2RA: 1.08-fold Up; FDR = 0.945; PValue = 0.766; mean CPM = 0.8493; interleukin 2 receptor, alpha" ID="ID_1534633359" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17F: 1.11-fold Down; FDR = 0.948; PValue = 0.771; mean CPM = 1.150; interleukin 17F" ID="ID_1842785916" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL21: 1.04-fold Up; FDR = 0.948; PValue = 0.773; mean CPM = 0.8164; interleukin 21" ID="ID_1505195471" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL13: 1.05-fold Up; FDR = 0.967; PValue = 0.805; mean CPM = 0.8212; interleukin 13" ID="ID_1828821736" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBX21: 1.09-fold Up; FDR = 0.972; PValue = 0.813; mean CPM = 0.9978; T-box 21" ID="ID_578812255" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12B: 1.07-fold Up; FDR = 0.983; PValue = 0.831; mean CPM = 0.8197; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)" ID="ID_1640180817" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL5: 1.05-fold Down; FDR = 1; PValue = 0.862; mean CPM = 1.367; interleukin 5 (colony-stimulating factor, eosinophil)" ID="ID_890324706" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCR3: 1.03-fold Up; FDR = 1; PValue = 0.943; mean CPM = 0.9843; chemokine (C-X-C motif) receptor 3" ID="ID_862496592" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL10: 1.21-fold Down; FDR = 1; PValue = 0.964; mean CPM = 0.8614; interleukin 10" ID="ID_1636984434" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40LG: 1.01-fold Down; FDR = 1; PValue = 0.982; mean CPM = 0.8653; CD40 ligand" ID="ID_94466374" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD86: 1.01-fold Down; FDR = 1; PValue = 0.99; mean CPM = 0.8012; CD86 molecule" ID="ID_596370608" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL23R: 1.05-fold Down; FDR = 1; PValue = 0.994; mean CPM = 0.7958; interleukin 23 receptor" ID="ID_1674431482" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2: 1.03-fold Up; FDR = 1; PValue = 0.998; mean CPM = 0.7974; interleukin 2" ID="ID_873124265" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Cell adhesion molecules: FDR = 1.55e-10, PValue = 2.65e-11" ID="ID_849193971" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="ENSMMUP00000027180: 6.97-fold Up; FDR = 1.24e-21; PValue = 3.39e-24; mean CPM = 285.4; Uncharacterized protein" ID="ID_819596837" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000027180: 6.97-fold Up; FDR = 1.24e-21; PValue = 3.39e-24; mean CPM = 285.4; Uncharacterized protein" ID="ID_267096573" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000005183: 4.07-fold Up; FDR = 2.87e-21; PValue = 8.51e-24; mean CPM = 164.7; Uncharacterized protein" ID="ID_1727859916" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000005183: 4.07-fold Up; FDR = 2.87e-21; PValue = 8.51e-24; mean CPM = 164.7; Uncharacterized protein" ID="ID_1989559511" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD274: 21.5-fold Up; FDR = 4.64e-21; PValue = 1.39e-23; mean CPM = 62.62; Macaca mulatta CD274 molecule (CD274), mRNA." ID="ID_1043734950" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-B: 6.07-fold Up; FDR = 2.71e-19; PValue = 1.2e-21; mean CPM = 2098; Uncharacterized protein" ID="ID_1073969603" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICAM1: 24.6-fold Up; FDR = 2.39e-17; PValue = 1.64e-19; mean CPM = 232.4; intercellular adhesion molecule 1" ID="ID_10745396" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DMB: 17.5-fold Up; FDR = 2.77e-15; PValue = 2.66e-17; mean CPM = 9.464; HLA class II histocompatibility antigen, DM beta chain Precursor (MHC class II antigen DMB)(Really interesting new gene 7 protein)" ID="ID_1378984943" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DPA1: 107-fold Up; FDR = 5.97e-15; PValue = 6.11e-17; mean CPM = 17.08; HLA class II histocompatibility antigen, DP alpha 1 chain Precursor (HLA-SB alpha chain)(MHC class II DP3-alpha)(DP(W3))(DP(W4))" ID="ID_1099724187" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDCD1LG2: 5.48-fold Up; FDR = 1.11e-13; PValue = 1.46e-15; mean CPM = 28.34; programmed cell death 1 ligand 2" ID="ID_15859945" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DQB1: 31.1-fold Up; FDR = 6.93e-13; PValue = 1.1e-14; mean CPM = 6.675; Macaca mulatta MHC class II antigen (MAMU-DRB), mRNA." ID="ID_1737119823" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD276: 1.83-fold Down; FDR = 2.04e-11; PValue = 4.56e-13; mean CPM = 65.28; CD276 molecule" ID="ID_1150657681" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAV: 2.64-fold Down; FDR = 6.04e-11; PValue = 1.51e-12; mean CPM = 337.3; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)" ID="ID_1162360819" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDH2: 2.24-fold Down; FDR = 2.51e-10; PValue = 7.39e-12; mean CPM = 402.4; cadherin 2, type 1, N-cadherin (neuronal)" ID="ID_1999085070" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPRF: 2.51-fold Down; FDR = 5.51e-10; PValue = 1.77e-11; mean CPM = 184.0; protein tyrosine phosphatase, receptor type, F" ID="ID_1939912692" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB8: 3.97-fold Up; FDR = 6.37e-10; PValue = 2.06e-11; mean CPM = 11.37; integrin, beta 8" ID="ID_1543339746" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VCAN: 2.98-fold Down; FDR = 6.04e-09; PValue = 2.48e-10; mean CPM = 2567; versican" ID="ID_1295191938" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SDC2: 1.91-fold Down; FDR = 6.94e-09; PValue = 2.87e-10; mean CPM = 168.5; syndecan 2" ID="ID_1694213325" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CNTNAP1: 2.24-fold Down; FDR = 1.39e-08; PValue = 6.26e-10; mean CPM = 15.44; contactin associated protein 1" ID="ID_1580298945" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAM3: 1.66-fold Down; FDR = 1.46e-08; PValue = 6.62e-10; mean CPM = 47.05; junctional adhesion molecule 3" ID="ID_975196602" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA1: 15.1-fold Up; FDR = 1.9e-08; PValue = 8.86e-10; mean CPM = 3.665; HLA class II histocompatibility antigen, DQ alpha 1 chain precursor" ID="ID_835993394" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DPB1: 7.73-fold Up; FDR = 4.73e-08; PValue = 2.45e-09; mean CPM = 1.528; Macaca mulatta major histocompatibility complex, class II, DP beta (MAMU-DPB), mRNA." ID="ID_731240611" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA8: 4.04-fold Down; FDR = 5.89e-08; PValue = 3.12e-09; mean CPM = 145.8; integrin, alpha 8" ID="ID_1924198986" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SDC4: 1.79-fold Up; FDR = 1.95e-07; PValue = 1.16e-08; mean CPM = 109.0; syndecan 4" ID="ID_580229516" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SDC1: 2.19-fold Down; FDR = 2.55e-05; PValue = 2.66e-06; mean CPM = 12.60; syndecan 1" ID="ID_524871491" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD99: 1.41-fold Down; FDR = 4.92e-05; PValue = 5.57e-06; mean CPM = 352.5; CD99 molecule" ID="ID_438870121" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLGN2: 1.64-fold Down; FDR = 6.24e-05; PValue = 7.29e-06; mean CPM = 14.59; neuroligin 2" ID="ID_1982999068" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPRC: 6.08-fold Up; FDR = 0.000285; PValue = 4.07e-05; mean CPM = 1.220; protein tyrosine phosphatase, receptor type, C" ID="ID_1223486038" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40: 2.76-fold Up; FDR = 0.00039; PValue = 5.79e-05; mean CPM = 9.139; CD40 molecule, TNF receptor superfamily member 5" ID="ID_309587607" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NRCAM: 2.04-fold Down; FDR = 0.00042; PValue = 6.29e-05; mean CPM = 7.571; Uncharacterized protein" ID="ID_1779666617" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD34: 2.84-fold Up; FDR = 0.000647; PValue = 0.000102; mean CPM = 1.700; CD34 molecule" ID="ID_521230453" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLDN2: 2.23-fold Down; FDR = 0.00218; PValue = 0.000409; mean CPM = 1.832; claudin 2" ID="ID_1915164759" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GLG1: 1.28-fold Down; FDR = 0.00336; PValue = 0.000671; mean CPM = 229.6; golgi glycoprotein 1" ID="ID_1220600606" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CADM3: 2.54-fold Up; FDR = 0.00366; PValue = 0.000742; mean CPM = 3.739; cell adhesion molecule 3" ID="ID_236121768" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NRXN2: 3.89-fold Down; FDR = 0.0116; PValue = 0.0028; mean CPM = 1.629; neurexin 2" ID="ID_851730742" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SELE: 4.04-fold Down; FDR = 0.0118; PValue = 0.00285; mean CPM = 0.9962; selectin E" ID="ID_346518841" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="OCLN: 2.09-fold Down; FDR = 0.012; PValue = 0.00291; mean CPM = 2.598; occludin" ID="ID_1698642811" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CNTN1: 2.61-fold Down; FDR = 0.0121; PValue = 0.00294; mean CPM = 1.505; contactin 1" ID="ID_1510294473" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPRM: 1.23-fold Down; FDR = 0.0136; PValue = 0.00334; mean CPM = 137.6; protein tyrosine phosphatase, receptor type, M" ID="ID_1386819969" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB2: 1.55-fold Down; FDR = 0.0187; PValue = 0.00485; mean CPM = 34.87; Integrin beta" ID="ID_636625380" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NEGR1: 1.42-fold Down; FDR = 0.0227; PValue = 0.00608; mean CPM = 10.40; neuronal growth regulator 1" ID="ID_1754618503" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLDN19: 3.2-fold Down; FDR = 0.0255; PValue = 0.00696; mean CPM = 0.9715; claudin 19" ID="ID_1677442745" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDH15: 2.95-fold Down; FDR = 0.0333; PValue = 0.00955; mean CPM = 0.9244; cadherin 15, type 1, M-cadherin (myotubule)" ID="ID_719141577" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VCAM1: 1.53-fold Up; FDR = 0.0353; PValue = 0.0102; mean CPM = 110.0; vascular cell adhesion molecule 1" ID="ID_126213969" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PVRL3: 1.22-fold Up; FDR = 0.037; PValue = 0.0108; mean CPM = 29.58; poliovirus receptor-related 3" ID="ID_348098490" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SDC3: 1.2-fold Down; FDR = 0.0585; PValue = 0.0186; mean CPM = 64.27; syndecan 3" ID="ID_1672447021" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CNTN2: 2.73-fold Down; FDR = 0.0614; PValue = 0.0196; mean CPM = 0.9153; contactin 2 (axonal)" ID="ID_1682606570" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DOA: 2.74-fold Up; FDR = 0.0694; PValue = 0.0227; mean CPM = 0.9089; HLA class II histocompatibility antigen, DO alpha chain Precursor (MHC class II antigen DOA)(MHC DZ alpha)(MHC DN-alpha)" ID="ID_1149077744" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB1: 1.23-fold Up; FDR = 0.0759; PValue = 0.0253; mean CPM = 2700; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)" ID="ID_950955105" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLGN1: 1.91-fold Down; FDR = 0.0998; PValue = 0.0349; mean CPM = 1.272; neuroligin 1" ID="ID_708361046" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLDN1: 1.57-fold Up; FDR = 0.1; PValue = 0.0352; mean CPM = 7.527; claudin 1" ID="ID_218660712" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="F11R: 1.41-fold Down; FDR = 0.113; PValue = 0.0407; mean CPM = 11.52; Uncharacterized protein" ID="ID_1719302097" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PVRL1: 1.47-fold Down; FDR = 0.119; PValue = 0.0431; mean CPM = 2.907; poliovirus receptor-related 1 (herpesvirus entry mediator C)" ID="ID_604975922" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPN: 2.27-fold Down; FDR = 0.157; PValue = 0.0608; mean CPM = 0.9319; sialophorin" ID="ID_324709364" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLDN22: 1.51-fold Down; FDR = 0.17; PValue = 0.0669; mean CPM = 1.862; claudin 22" ID="ID_1203607246" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLDN4: 2-fold Down; FDR = 0.175; PValue = 0.0694; mean CPM = 1.622; claudin 4" ID="ID_1934210232" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ALCAM: 1.26-fold Down; FDR = 0.234; PValue = 0.0995; mean CPM = 41.17; activated leukocyte cell adhesion molecule" ID="ID_119788143" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLDN11: 1.67-fold Down; FDR = 0.304; PValue = 0.138; mean CPM = 1.115; claudin 11" ID="ID_1489613583" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDH3: 1.78-fold Down; FDR = 0.349; PValue = 0.163; mean CPM = 0.9566; Uncharacterized protein" ID="ID_242525157" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014796: 1.77-fold Up; FDR = 0.381; PValue = 0.182; mean CPM = 0.9085; Uncharacterized protein" ID="ID_706668942" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLDN5: 2.59-fold Down; FDR = 0.425; PValue = 0.209; mean CPM = 0.8375; claudin 5" ID="ID_1431362551" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CNTNAP2: 1.48-fold Down; FDR = 0.515; PValue = 0.268; mean CPM = 1.160; contactin associated protein-like 2" ID="ID_1958507974" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PVRL2: 1.08-fold Down; FDR = 0.552; PValue = 0.295; mean CPM = 35.47; poliovirus receptor-related 2 (herpesvirus entry mediator B)" ID="ID_913603185" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLDN14: 1.57-fold Down; FDR = 0.588; PValue = 0.321; mean CPM = 0.8761; claudin 14" ID="ID_152550955" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA9: 1.3-fold Down; FDR = 0.595; PValue = 0.326; mean CPM = 1.685; integrin, alpha 9" ID="ID_485863965" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="L1CAM: 1.34-fold Down; FDR = 0.601; PValue = 0.331; mean CPM = 2.064; Uncharacterized protein" ID="ID_1759207060" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLDN16: 1.44-fold Down; FDR = 0.623; PValue = 0.346; mean CPM = 1.045; claudin 16" ID="ID_1386078323" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICAM3: 1.1-fold Down; FDR = 0.685; PValue = 0.395; mean CPM = 7.797; intercellular adhesion molecule 3" ID="ID_569598562" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDH4: 1.42-fold Down; FDR = 0.714; PValue = 0.418; mean CPM = 0.8874; Uncharacterized protein" ID="ID_1918898052" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA4: 1.16-fold Down; FDR = 0.722; PValue = 0.425; mean CPM = 5.425; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)" ID="ID_878883235" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAM: 1.44-fold Down; FDR = 0.73; PValue = 0.432; mean CPM = 0.9052; integrin, alpha M (complement component 3 receptor 3 subunit)" ID="ID_990503907" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLDN15: 1.11-fold Down; FDR = 0.738; PValue = 0.439; mean CPM = 5.245; claudin 15" ID="ID_715314956" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLDN6: 1.37-fold Down; FDR = 0.751; PValue = 0.452; mean CPM = 0.9260; claudin 6" ID="ID_1825419166" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLGN3: 1.27-fold Down; FDR = 0.783; PValue = 0.48; mean CPM = 1.180; neuroligin 3" ID="ID_1085186544" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD4: 1.27-fold Up; FDR = 0.807; PValue = 0.503; mean CPM = 1.122; CD4 molecule" ID="ID_527077987" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTLA4: 1.41-fold Down; FDR = 0.827; PValue = 0.527; mean CPM = 0.8017; cytotoxic T-lymphocyte-associated protein 4" ID="ID_506292632" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLDN18: 1.49-fold Down; FDR = 0.833; PValue = 0.535; mean CPM = 0.8235; claudin 18" ID="ID_1619806794" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICAM2: 1.26-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 0.9289; intercellular adhesion molecule 2" ID="ID_1553969470" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD58: 1.04-fold Down; FDR = 0.889; PValue = 0.612; mean CPM = 21.84; CD58 molecule" ID="ID_886247409" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DRB: 1.28-fold Up; FDR = 0.898; PValue = 0.624; mean CPM = 0.8112; MHC class II antigen; Uncharacterized protein" ID="ID_1001063876" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SIGLEC1: 1.23-fold Down; FDR = 0.899; PValue = 0.626; mean CPM = 0.9801; sialic acid binding Ig-like lectin 1, sialoadhesin" ID="ID_374496237" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MPZL1: 1.03-fold Up; FDR = 0.902; PValue = 0.639; mean CPM = 84.36; myelin protein zero-like 1" ID="ID_561990058" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD2: 1.42-fold Up; FDR = 0.903; PValue = 0.641; mean CPM = 0.8179; CD2 molecule" ID="ID_139220790" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDCD1: 1.5-fold Down; FDR = 0.903; PValue = 0.644; mean CPM = 0.8258; programmed cell death 1" ID="ID_99107564" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000024680: 1.21-fold Down; FDR = 0.903; PValue = 0.647; mean CPM = 0.7890; Uncharacterized protein" ID="ID_770509734" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLDN8: 1.13-fold Up; FDR = 0.908; PValue = 0.677; mean CPM = 0.7894; claudin 8" ID="ID_1163683933" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA2: 1.13-fold Up; FDR = 0.908; PValue = 0.681; mean CPM = 0.7877; HLA class II histocompatibility antigen, DQ alpha 2 chain Precursor (HLA class II histocompatibility antigen, DQ(6) alpha chain)(DX alpha chain)(HLA-DQA1)" ID="ID_1225518279" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICOSLG: 1.07-fold Down; FDR = 0.909; PValue = 0.684; mean CPM = 6.739; inducible T-cell co-stimulator ligand" ID="ID_337894758" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MADCAM1: 1.11-fold Up; FDR = 0.909; PValue = 0.688; mean CPM = 0.7934; mucosal vascular addressin cell adhesion molecule 1" ID="ID_1339202999" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICOS: 1.19-fold Up; FDR = 0.931; PValue = 0.741; mean CPM = 0.8158; Uncharacterized protein" ID="ID_230005407" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD6: 1.11-fold Up; FDR = 0.931; PValue = 0.742; mean CPM = 1.320; CD6 molecule" ID="ID_1253488429" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SELP: 1.2-fold Down; FDR = 0.942; PValue = 0.76; mean CPM = 0.8693; selectin P (granule membrane protein 140kDa, antigen CD62)" ID="ID_1854965647" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDH5: 1.13-fold Down; FDR = 0.95; PValue = 0.776; mean CPM = 0.8935; cadherin 5, type 2 (vascular endothelium)" ID="ID_730517369" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAG: 1.17-fold Up; FDR = 0.953; PValue = 0.782; mean CPM = 0.8629; myelin associated glycoprotein" ID="ID_81083498" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLDN10: 1.22-fold Down; FDR = 0.957; PValue = 0.79; mean CPM = 0.8494; claudin 10" ID="ID_1395338233" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD80: 1.08-fold Up; FDR = 0.971; PValue = 0.812; mean CPM = 1.157; CD80 molecule" ID="ID_699418663" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NEO1: 1.03-fold Down; FDR = 0.974; PValue = 0.816; mean CPM = 107.7; neogenin homolog 1 (chicken)" ID="ID_1290545887" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDH1: 1.06-fold Down; FDR = 1; PValue = 0.899; mean CPM = 0.8823; cadherin 1, type 1, E-cadherin (epithelial)" ID="ID_3394605" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD22: 1.18-fold Down; FDR = 1; PValue = 0.928; mean CPM = 0.8572; CD22 molecule" ID="ID_185816329" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAL: 1.03-fold Up; FDR = 1; PValue = 0.95; mean CPM = 1.035; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)" ID="ID_1923290040" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB7: 1.01-fold Down; FDR = 1; PValue = 0.968; mean CPM = 2.025; integrin, beta 7" ID="ID_1827679554" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLDN9: 1.07-fold Down; FDR = 1; PValue = 0.969; mean CPM = 0.8006; claudin 9" ID="ID_1212396483" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD8A: No Change; FDR = 1; PValue = 0.98; mean CPM = 0.8052; CD8a molecule" ID="ID_907002978" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40LG: 1.01-fold Down; FDR = 1; PValue = 0.982; mean CPM = 0.8653; CD40 ligand" ID="ID_582522824" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD86: 1.01-fold Down; FDR = 1; PValue = 0.99; mean CPM = 0.8012; CD86 molecule" ID="ID_1372301532" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SELL: 1.04-fold Up; FDR = 1; PValue = 0.995; mean CPM = 0.8177; Macaca mulatta selectin L (SELL), mRNA." ID="ID_1830817913" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NRXN1: 1.07-fold Up; FDR = 1; PValue = 0.999; mean CPM = 0.8440; neurexin 1" ID="ID_1578351729" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ESAM: 1.01-fold Down; FDR = 1; PValue = 1; mean CPM = 1.217; endothelial cell adhesion molecule" ID="ID_1521527537" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD226: No Change; FDR = 1; PValue = 1; mean CPM = 0.7800; CD226 molecule" ID="ID_839769052" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLDN17: No Change; FDR = 1; PValue = 1; mean CPM = 0.7843; claudin 17" ID="ID_1243328957" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IFN alpha/beta: FDR = 1.55e-10, PValue = 2.87e-11" ID="ID_13392492" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TAP1: 8.86-fold Up; FDR = 4.25e-27; PValue = 3.99e-31; mean CPM = 524.4; Antigen peptide transporter 1 (APT1)(Peptide transporter TAP1)(ATP-binding cassette sub-family B member 2)(Peptide supply factor 1)(Peptide transporter PSF1)(PSF-1)(Peptide transporter involved in antigen processing 1)(Really interesting new gene 4 /.../n)" ID="ID_370435228" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMB8: 15.4-fold Up; FDR = 1.64e-26; PValue = 5.69e-30; mean CPM = 246.0; proteasome subunit beta type-8 isoform E1 proprotein" ID="ID_676898458" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFITM1: 22.3-fold Up; FDR = 1.43e-23; PValue = 2.15e-26; mean CPM = 454.0; interferon induced transmembrane protein 1" ID="ID_502863974" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFIH1: 14.7-fold Up; FDR = 8.74e-23; PValue = 1.68e-25; mean CPM = 49.84; interferon induced with helicase C domain 1" ID="ID_856474839" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF1: 18.6-fold Up; FDR = 1.53e-21; PValue = 4.24e-24; mean CPM = 240.7; interferon regulatory factor 1" ID="ID_233223774" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="OAS1: 41-fold Up; FDR = 1.01e-20; PValue = 3.28e-23; mean CPM = 37.38; Macaca mulatta 2',5'-oligoadenylate synthetase 1, 40/46kDa (OAS1), mRNA." ID="ID_1297134309" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFIT1: 52.1-fold Up; FDR = 1.76e-20; PValue = 6.3e-23; mean CPM = 46.34; interferon-induced protein with tetratricopeptide repeats 1" ID="ID_890691738" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFIT3: 63.7-fold Up; FDR = 7.87e-20; PValue = 3e-22; mean CPM = 372.5; interferon-induced protein with tetratricopeptide repeats 3" ID="ID_211255331" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MX1: 48.9-fold Up; FDR = 9.52e-20; PValue = 3.71e-22; mean CPM = 84.25; myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)" ID="ID_12517615" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF9: 3.85-fold Up; FDR = 2.6e-19; PValue = 1.12e-21; mean CPM = 106.4; interferon regulatory factor 9" ID="ID_1866432119" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT2: 2.67-fold Up; FDR = 8.02e-19; PValue = 4.03e-21; mean CPM = 185.6; signal transducer and activator of transcription 2, 113kDa" ID="ID_736665696" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_1623010161" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_718126786" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ISG15: 15.5-fold Up; FDR = 2.16e-15; PValue = 2.02e-17; mean CPM = 55.60; ISG15 ubiquitin-like modifier" ID="ID_793664138" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN2: 1.87-fold Up; FDR = 6.19e-10; PValue = 2e-11; mean CPM = 32.46; protein tyrosine phosphatase, non-receptor type 2" ID="ID_424338627" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_139134836" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR2: 1.74-fold Up; FDR = 1.85e-06; PValue = 1.44e-07; mean CPM = 26.05; interferon (alpha, beta and omega) receptor 2" ID="ID_1643314758" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR1: 1.31-fold Up; FDR = 0.00151; PValue = 0.000268; mean CPM = 37.77; interferon gamma receptor 1" ID="ID_576754307" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIAS1: 1.3-fold Up; FDR = 0.00259; PValue = 0.000498; mean CPM = 29.99; protein inhibitor of activated STAT, 1" ID="ID_306288543" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL18: 1.5-fold Down; FDR = 0.00981; PValue = 0.0023; mean CPM = 6.489; interleukin 18 (interferon-gamma-inducing factor)" ID="ID_189254003" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR1: 1.27-fold Up; FDR = 0.0101; PValue = 0.00237; mean CPM = 82.39; Uncharacterized protein" ID="ID_1116734905" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYK2: 1.24-fold Down; FDR = 0.0142; PValue = 0.00354; mean CPM = 42.58; tyrosine kinase 2" ID="ID_1485048781" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR2: 1.23-fold Up; FDR = 0.0258; PValue = 0.00707; mean CPM = 46.52; interferon gamma receptor 2 (interferon gamma transducer 1)" ID="ID_1981462539" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_723737710" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2: 1.48-fold Up; FDR = 0.384; PValue = 0.184; mean CPM = 1.344; Uncharacterized protein" ID="ID_1958288036" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016250: 1.52-fold Up; FDR = 0.419; PValue = 0.205; mean CPM = 1.143" ID="ID_1020448961" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNB1: 1.79-fold Up; FDR = 0.731; PValue = 0.433; mean CPM = 0.8526; interferon, beta 1, fibroblast" ID="ID_1466167139" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFITM1: 1.63-fold Up; FDR = 0.767; PValue = 0.465; mean CPM = 0.8148; interferon induced transmembrane protein 1 (9-27)" ID="ID_1214665304" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAX: 1.05-fold Up; FDR = 0.809; PValue = 0.506; mean CPM = 162.4; Uncharacterized protein" ID="ID_1015154423" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_93657281" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000028965: 1.11-fold Up; FDR = 0.911; PValue = 0.697; mean CPM = 1.501; Uncharacterized protein" ID="ID_1514155248" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MED14: 1.01-fold Down; FDR = 1; PValue = 0.916; mean CPM = 56.17; mediator complex subunit 14" ID="ID_1672996739" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA1: No Change; FDR = 1; PValue = 0.998; mean CPM = 0.8014; interferon, alpha 1" ID="ID_1794086337" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-17 : FDR = 1.88e-10, PValue = 3.82e-11" ID="ID_144342884" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CXCL10: 462-fold Up; FDR = 1.01e-21; PValue = 2.65e-24; mean CPM = 286.2; Macaca mulatta chemokine (C-X-C motif) ligand 10 (CXCL10), mRNA." ID="ID_68358710" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL11: 256-fold Up; FDR = 1e-19; PValue = 3.96e-22; mean CPM = 84.82; chemokine (C-X-C motif) ligand 11" ID="ID_224238106" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_1631707531" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL2: 24.6-fold Up; FDR = 1.83e-15; PValue = 1.69e-17; mean CPM = 668.2; Macaca mulatta chemokine (C-C motif) ligand 2 (CCL2), mRNA." ID="ID_725236939" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_634034651" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_507869127" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_695135826" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17B: 4.36-fold Down; FDR = 2.84e-06; PValue = 2.29e-07; mean CPM = 1.984; interleukin 17B" ID="ID_861229330" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K3: 1.45-fold Down; FDR = 7.01e-06; PValue = 6.34e-07; mean CPM = 180.1; mitogen-activated protein kinase kinase 3" ID="ID_904659759" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1113762080" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL11: 6.86-fold Up; FDR = 2.69e-05; PValue = 2.82e-06; mean CPM = 4.204; chemokine (C-C motif) ligand 11" ID="ID_1815262435" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17RD: 2.25-fold Down; FDR = 0.000136; PValue = 1.75e-05; mean CPM = 2.474; interleukin 17 receptor D" ID="ID_948939868" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTGS2: 2.02-fold Up; FDR = 0.000254; PValue = 3.59e-05; mean CPM = 314.5; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)" ID="ID_662943023" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF2: 1.34-fold Up; FDR = 0.000403; PValue = 6.01e-05; mean CPM = 39.83; activating transcription factor 2" ID="ID_1955661638" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL1: 2.18-fold Up; FDR = 0.00609; PValue = 0.00133; mean CPM = 45.92; chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)" ID="ID_104644900" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K14: 1.47-fold Down; FDR = 0.00704; PValue = 0.00157; mean CPM = 9.470; mitogen-activated protein kinase kinase kinase 14" ID="ID_575153451" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_51230247" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL8: 2.33-fold Up; FDR = 0.0209; PValue = 0.00552; mean CPM = 2326; interleukin 8" ID="ID_1286086608" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17D: 1.45-fold Down; FDR = 0.0235; PValue = 0.00633; mean CPM = 5.355; interleukin 17D" ID="ID_1244357744" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17RE: 2.26-fold Down; FDR = 0.0313; PValue = 0.00886; mean CPM = 1.420; interleukin 17 receptor E" ID="ID_1063164628" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1073722629" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_721401827" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP3: 3.29-fold Down; FDR = 0.104; PValue = 0.037; mean CPM = 81.12; matrix metallopeptidase 3 (stromelysin 1, progelatinase)" ID="ID_1534700052" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17RA: 1.16-fold Up; FDR = 0.121; PValue = 0.0443; mean CPM = 48.31; interleukin 17 receptor A" ID="ID_1145552178" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_888886385" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_60171887" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_1330395069" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_554498349" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL19: 1.65-fold Down; FDR = 0.455; PValue = 0.228; mean CPM = 0.9514; interleukin 19" ID="ID_1817162417" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17RC: 1.08-fold Down; FDR = 0.572; PValue = 0.31; mean CPM = 43.18; interleukin 17 receptor C" ID="ID_907310796" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPKAPK2: 1.06-fold Down; FDR = 0.733; PValue = 0.435; mean CPM = 82.16; mitogen-activated protein kinase-activated protein kinase 2" ID="ID_451848732" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17RB: 1.24-fold Down; FDR = 0.752; PValue = 0.452; mean CPM = 1.299; interleukin 17 receptor B" ID="ID_182463768" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_303215042" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL25: 1.24-fold Down; FDR = 0.899; PValue = 0.631; mean CPM = 0.7976; interleukin 25" ID="ID_1810295789" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17A: 1.12-fold Up; FDR = 0.911; PValue = 0.706; mean CPM = 0.7895; interleukin 17A" ID="ID_715676882" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOS2: 1.4-fold Down; FDR = 0.917; PValue = 0.718; mean CPM = 0.8546; nitric oxide synthase 2, inducible" ID="ID_471662679" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17F: 1.11-fold Down; FDR = 0.948; PValue = 0.771; mean CPM = 1.150; interleukin 17F" ID="ID_680329062" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_1111739597" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF3IP2: 1.01-fold Down; FDR = 1; PValue = 0.913; mean CPM = 29.19; TRAF3 interacting protein 2" ID="ID_929555200" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRP: No Change; FDR = 1; PValue = 1; mean CPM = 0.7818; Uncharacterized protein" ID="ID_667890206" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-13: FDR = 2.02e-10, PValue = 4.62e-11" ID="ID_436464060" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1008027143" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DMB: 17.5-fold Up; FDR = 2.77e-15; PValue = 2.66e-17; mean CPM = 9.464; HLA class II histocompatibility antigen, DM beta chain Precursor (MHC class II antigen DMB)(Really interesting new gene 7 protein)" ID="ID_1989754474" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DPA1: 107-fold Up; FDR = 5.97e-15; PValue = 6.11e-17; mean CPM = 17.08; HLA class II histocompatibility antigen, DP alpha 1 chain Precursor (HLA-SB alpha chain)(MHC class II DP3-alpha)(DP(W3))(DP(W4))" ID="ID_1412420176" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DQB1: 31.1-fold Up; FDR = 6.93e-13; PValue = 1.1e-14; mean CPM = 6.675; Macaca mulatta MHC class II antigen (MAMU-DRB), mRNA." ID="ID_1836950395" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_1078891141" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL13RA1: 1.73-fold Up; FDR = 1.81e-09; PValue = 6.5e-11; mean CPM = 42.50; interleukin 13 receptor, alpha 1" ID="ID_1192238918" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_703194761" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRS1: 2.78-fold Up; FDR = 7.67e-09; PValue = 3.19e-10; mean CPM = 26.55; Uncharacterized protein" ID="ID_1293111754" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA1: 15.1-fold Up; FDR = 1.9e-08; PValue = 8.86e-10; mean CPM = 3.665; HLA class II histocompatibility antigen, DQ alpha 1 chain precursor" ID="ID_1413856593" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DPB1: 7.73-fold Up; FDR = 4.73e-08; PValue = 2.45e-09; mean CPM = 1.528; Macaca mulatta major histocompatibility complex, class II, DP beta (MAMU-DPB), mRNA." ID="ID_1996101287" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1530731831" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_469753279" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CISH: 1.95-fold Up; FDR = 0.00116; PValue = 0.0002; mean CPM = 5.083; cytokine inducible SH2-containing protein" ID="ID_950955655" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK3: 2.31-fold Up; FDR = 0.00186; PValue = 0.000342; mean CPM = 2.154; Janus kinase 3" ID="ID_971064705" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYK2: 1.24-fold Down; FDR = 0.0142; PValue = 0.00354; mean CPM = 42.58; tyrosine kinase 2" ID="ID_1973244131" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB2: 1.55-fold Down; FDR = 0.0187; PValue = 0.00485; mean CPM = 34.87; Integrin beta" ID="ID_609231731" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VCAM1: 1.53-fold Up; FDR = 0.0353; PValue = 0.0102; mean CPM = 110.0; vascular cell adhesion molecule 1" ID="ID_535254379" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DOA: 2.74-fold Up; FDR = 0.0694; PValue = 0.0227; mean CPM = 0.9089; HLA class II histocompatibility antigen, DO alpha chain Precursor (MHC class II antigen DOA)(MHC DZ alpha)(MHC DN-alpha)" ID="ID_965128792" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT6: 1.18-fold Up; FDR = 0.0727; PValue = 0.024; mean CPM = 217.5; signal transducer and activator of transcription 6, interleukin-4 induced" ID="ID_475512206" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB1: 1.23-fold Up; FDR = 0.0759; PValue = 0.0253; mean CPM = 2700; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)" ID="ID_797489343" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL13RA2: 2.13-fold Up; FDR = 0.0909; PValue = 0.0313; mean CPM = 1.485; Interleukin-13 receptor subunit alpha-2; Uncharacterized protein" ID="ID_479388055" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_1999825462" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS2: 1.17-fold Up; FDR = 0.1; PValue = 0.0353; mean CPM = 31.79; son of sevenless homolog 2 (Drosophila)" ID="ID_1281303957" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_957160781" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_362241077" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014796: 1.77-fold Up; FDR = 0.381; PValue = 0.182; mean CPM = 0.9085; Uncharacterized protein" ID="ID_1930193016" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_828901372" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_1717279467" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_1333225926" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAM: 1.44-fold Down; FDR = 0.73; PValue = 0.432; mean CPM = 0.9052; integrin, alpha M (complement component 3 receptor 3 subunit)" ID="ID_1413983311" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL4R: 1.05-fold Down; FDR = 0.803; PValue = 0.499; mean CPM = 193.5; interleukin 4 receptor" ID="ID_1324957097" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FCER2: 1.41-fold Up; FDR = 0.864; PValue = 0.58; mean CPM = 0.8258; Fc fragment of IgE, low affinity II, receptor for (CD23)" ID="ID_819038076" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DRB: 1.28-fold Up; FDR = 0.898; PValue = 0.624; mean CPM = 0.8112; MHC class II antigen; Uncharacterized protein" ID="ID_448196639" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA2: 1.13-fold Up; FDR = 0.908; PValue = 0.681; mean CPM = 0.7877; HLA class II histocompatibility antigen, DQ alpha 2 chain Precursor (HLA class II histocompatibility antigen, DQ(6) alpha chain)(DX alpha chain)(HLA-DQA1)" ID="ID_1435721210" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL13: 1.05-fold Up; FDR = 0.967; PValue = 0.805; mean CPM = 0.8212; interleukin 13" ID="ID_689360183" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="OX40: FDR = 2.02e-10, PValue = 5.21e-11" ID="ID_821105770" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="ENSMMUP00000027180: 6.97-fold Up; FDR = 1.24e-21; PValue = 3.39e-24; mean CPM = 285.4; Uncharacterized protein" ID="ID_222210044" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000027180: 6.97-fold Up; FDR = 1.24e-21; PValue = 3.39e-24; mean CPM = 285.4; Uncharacterized protein" ID="ID_1186130180" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000005183: 4.07-fold Up; FDR = 2.87e-21; PValue = 8.51e-24; mean CPM = 164.7; Uncharacterized protein" ID="ID_422873682" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000005183: 4.07-fold Up; FDR = 2.87e-21; PValue = 8.51e-24; mean CPM = 164.7; Uncharacterized protein" ID="ID_271586915" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-B: 6.07-fold Up; FDR = 2.71e-19; PValue = 1.2e-21; mean CPM = 2098; Uncharacterized protein" ID="ID_640557885" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DMB: 17.5-fold Up; FDR = 2.77e-15; PValue = 2.66e-17; mean CPM = 9.464; HLA class II histocompatibility antigen, DM beta chain Precursor (MHC class II antigen DMB)(Really interesting new gene 7 protein)" ID="ID_695535015" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DPA1: 107-fold Up; FDR = 5.97e-15; PValue = 6.11e-17; mean CPM = 17.08; HLA class II histocompatibility antigen, DP alpha 1 chain Precursor (HLA-SB alpha chain)(MHC class II DP3-alpha)(DP(W3))(DP(W4))" ID="ID_410810096" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DQB1: 31.1-fold Up; FDR = 6.93e-13; PValue = 1.1e-14; mean CPM = 6.675; Macaca mulatta MHC class II antigen (MAMU-DRB), mRNA." ID="ID_291786909" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA1: 15.1-fold Up; FDR = 1.9e-08; PValue = 8.86e-10; mean CPM = 3.665; HLA class II histocompatibility antigen, DQ alpha 1 chain precursor" ID="ID_1872241486" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DPB1: 7.73-fold Up; FDR = 4.73e-08; PValue = 2.45e-09; mean CPM = 1.528; Macaca mulatta major histocompatibility complex, class II, DP beta (MAMU-DPB), mRNA." ID="ID_910269969" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L1: 1.51-fold Up; FDR = 9.13e-07; PValue = 6.52e-08; mean CPM = 66.15; Bcl-2-like protein 1; Bcl-2-like protein 1 isoform 1; Uncharacterized protein" ID="ID_705005625" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1850648309" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF4: 2.55-fold Down; FDR = 6.64e-06; PValue = 5.95e-07; mean CPM = 4.174; tumor necrosis factor (ligand) superfamily, member 4" ID="ID_304760010" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_1383849791" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_639616648" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBID: 1.47-fold Down; FDR = 0.0247; PValue = 0.0067; mean CPM = 6.446; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta" ID="ID_238436311" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIE: 1.3-fold Down; FDR = 0.0272; PValue = 0.00752; mean CPM = 16.93; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon" ID="ID_773068185" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_462028784" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKAP: 1.19-fold Down; FDR = 0.0434; PValue = 0.013; mean CPM = 50.22; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein" ID="ID_884094135" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DOA: 2.74-fold Up; FDR = 0.0694; PValue = 0.0227; mean CPM = 0.9089; HLA class II histocompatibility antigen, DO alpha chain Precursor (MHC class II antigen DOA)(MHC DZ alpha)(MHC DN-alpha)" ID="ID_1528963276" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIZ: 1.23-fold Up; FDR = 0.0949; PValue = 0.033; mean CPM = 91.08; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta" ID="ID_713643499" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_997152432" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_687197046" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014796: 1.77-fold Up; FDR = 0.381; PValue = 0.182; mean CPM = 0.9085; Uncharacterized protein" ID="ID_750266605" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2: 1.48-fold Up; FDR = 0.384; PValue = 0.184; mean CPM = 1.344; Uncharacterized protein" ID="ID_280132605" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF3: 1.07-fold Up; FDR = 0.611; PValue = 0.338; mean CPM = 34.56; TNF receptor-associated factor 3" ID="ID_380765380" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD247: 1.43-fold Down; FDR = 0.695; PValue = 0.404; mean CPM = 0.9076; Macaca mulatta CD247 molecule (CD247), mRNA." ID="ID_799981745" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF4: 1.36-fold Down; FDR = 0.743; PValue = 0.444; mean CPM = 0.8892; tumor necrosis factor receptor superfamily, member 4" ID="ID_20232529" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD4: 1.27-fold Up; FDR = 0.807; PValue = 0.503; mean CPM = 1.122; CD4 molecule" ID="ID_302659792" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DRB: 1.28-fold Up; FDR = 0.898; PValue = 0.624; mean CPM = 0.8112; MHC class II antigen; Uncharacterized protein" ID="ID_1770882712" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3D: 1.22-fold Down; FDR = 0.903; PValue = 0.641; mean CPM = 0.7953; CD3d molecule, delta (CD3-TCR complex)" ID="ID_36140281" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA2: 1.13-fold Up; FDR = 0.908; PValue = 0.681; mean CPM = 0.7877; HLA class II histocompatibility antigen, DQ alpha 2 chain Precursor (HLA class II histocompatibility antigen, DQ(6) alpha chain)(DX alpha chain)(HLA-DQA1)" ID="ID_657770981" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKE: 1.03-fold Up; FDR = 0.929; PValue = 0.737; mean CPM = 21.61; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon" ID="ID_1674280663" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_559453528" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3G: 1.03-fold Up; FDR = 1; PValue = 0.977; mean CPM = 0.8190; CD3g molecule, gamma (CD3-TCR complex)" ID="ID_51220105" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3E: 1.07-fold Down; FDR = 1; PValue = 0.981; mean CPM = 0.7994; Uncharacterized protein" ID="ID_1206359953" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2: 1.03-fold Up; FDR = 1; PValue = 0.998; mean CPM = 0.7974; interleukin 2" ID="ID_1525269858" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Natural killer cell mediated cytotoxicity: FDR = 2.02e-10, PValue = 5.23e-11" ID="ID_77784158" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="ENSMMUP00000027180: 6.97-fold Up; FDR = 1.24e-21; PValue = 3.39e-24; mean CPM = 285.4; Uncharacterized protein" ID="ID_1606290520" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000027180: 6.97-fold Up; FDR = 1.24e-21; PValue = 3.39e-24; mean CPM = 285.4; Uncharacterized protein" ID="ID_1257474143" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000005183: 4.07-fold Up; FDR = 2.87e-21; PValue = 8.51e-24; mean CPM = 164.7; Uncharacterized protein" ID="ID_1304769373" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000005183: 4.07-fold Up; FDR = 2.87e-21; PValue = 8.51e-24; mean CPM = 164.7; Uncharacterized protein" ID="ID_1501055433" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-B: 6.07-fold Up; FDR = 2.71e-19; PValue = 1.2e-21; mean CPM = 2098; Uncharacterized protein" ID="ID_1253409029" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICAM1: 24.6-fold Up; FDR = 2.39e-17; PValue = 1.64e-19; mean CPM = 232.4; intercellular adhesion molecule 1" ID="ID_1975770723" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF10: 44.5-fold Up; FDR = 2.83e-16; PValue = 2.4e-18; mean CPM = 6.029; Tumor necrosis factor ligand superfamily member 10 isoform 1; Uncharacterized protein" ID="ID_832434896" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC4: 7.09-fold Down; FDR = 1.82e-12; PValue = 3.1e-14; mean CPM = 6.421; SHC (Src homology 2 domain containing) family, member 4" ID="ID_523607648" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC4: 1.85-fold Down; FDR = 1.13e-11; PValue = 2.37e-13; mean CPM = 51.58; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4" ID="ID_360330338" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_20092121" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BID: 1.66-fold Up; FDR = 5.41e-09; PValue = 2.19e-10; mean CPM = 35.19; BH3 interacting domain death agonist" ID="ID_306441484" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2B: 3.54-fold Up; FDR = 1.24e-07; PValue = 7.07e-09; mean CPM = 5.971; PTK2B protein tyrosine kinase 2 beta" ID="ID_1682291704" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_1316598020" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_548703584" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_491472387" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR2: 1.74-fold Up; FDR = 1.85e-06; PValue = 1.44e-07; mean CPM = 26.05; interferon (alpha, beta and omega) receptor 2" ID="ID_521945307" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC3: 1.68-fold Down; FDR = 2.72e-06; PValue = 2.19e-07; mean CPM = 13.98; ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)" ID="ID_1759286730" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_56712036" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF10D: 1.84-fold Down; FDR = 5.9e-05; PValue = 6.84e-06; mean CPM = 32.06; tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain" ID="ID_1717197139" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ULBP3: 2.32-fold Down; FDR = 0.000296; PValue = 4.26e-05; mean CPM = 4.191; UL16 binding protein 3" ID="ID_1169532793" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP3CA: 1.55-fold Up; FDR = 0.0003; PValue = 4.32e-05; mean CPM = 40.21; protein phosphatase 3, catalytic subunit, alpha isozyme" ID="ID_901403802" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC2: 4.03-fold Down; FDR = 0.000346; PValue = 5.06e-05; mean CPM = 1.347; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2" ID="ID_429677266" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD48: 2.78-fold Down; FDR = 0.000425; PValue = 6.39e-05; mean CPM = 3.161; CD48 molecule" ID="ID_393189240" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAET1E: 3.45-fold Down; FDR = 0.00045; PValue = 6.8e-05; mean CPM = 1.834; retinoic acid early transcript 1E" ID="ID_505716135" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR1: 1.31-fold Up; FDR = 0.00151; PValue = 0.000268; mean CPM = 37.77; interferon gamma receptor 1" ID="ID_1708635579" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG1: 1.31-fold Down; FDR = 0.00352; PValue = 0.000707; mean CPM = 53.66; phospholipase C, gamma 1" ID="ID_921822438" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV3: 1.82-fold Down; FDR = 0.00463; PValue = 0.000973; mean CPM = 7.044; vav 3 guanine nucleotide exchange factor" ID="ID_1729998650" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR1: 1.27-fold Up; FDR = 0.0101; PValue = 0.00237; mean CPM = 82.39; Uncharacterized protein" ID="ID_1025303231" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FYN: 1.22-fold Up; FDR = 0.0156; PValue = 0.00393; mean CPM = 92.94; FYN oncogene related to SRC, FGR, YES" ID="ID_1907488847" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSF2: 2.96-fold Down; FDR = 0.0174; PValue = 0.00447; mean CPM = 73.98; colony stimulating factor 2 (granulocyte-macrophage)" ID="ID_444186658" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB2: 1.55-fold Down; FDR = 0.0187; PValue = 0.00485; mean CPM = 34.87; Integrin beta" ID="ID_706782134" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1903338980" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AC012652.1: 1.23-fold Down; FDR = 0.0201; PValue = 0.0053; mean CPM = 33.80; Calcium-binding protein p22 (Calcium-binding protein CHP)(Calcineurin homologous protein)(Calcineurin B homolog)" ID="ID_1849770097" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR2: 1.23-fold Up; FDR = 0.0258; PValue = 0.00707; mean CPM = 46.52; interferon gamma receptor 2 (interferon gamma transducer 1)" ID="ID_1082350938" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFAT5: 1.21-fold Up; FDR = 0.0273; PValue = 0.00754; mean CPM = 113.0; nuclear factor of activated T-cells 5, tonicity-responsive" ID="ID_1093269766" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC2: 2.96-fold Up; FDR = 0.0309; PValue = 0.00872; mean CPM = 0.9737; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)" ID="ID_216155747" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KRAS: 1.35-fold Down; FDR = 0.0401; PValue = 0.0119; mean CPM = 13.10; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog" ID="ID_1463127271" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NRAS: 1.2-fold Down; FDR = 0.0546; PValue = 0.017; mean CPM = 32.39; neuroblastoma RAS viral (v-ras) oncogene homolog" ID="ID_382178284" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_1530577296" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS2: 1.17-fold Up; FDR = 0.1; PValue = 0.0353; mean CPM = 31.79; son of sevenless homolog 2 (Drosophila)" ID="ID_1311444612" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HCST: 1.47-fold Down; FDR = 0.129; PValue = 0.0478; mean CPM = 2.995; hematopoietic cell signal transducer" ID="ID_1399910049" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAET1G: 1.58-fold Down; FDR = 0.143; PValue = 0.0544; mean CPM = 1.944; retinoic acid early transcript 1G" ID="ID_319183645" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC2: 1.34-fold Down; FDR = 0.191; PValue = 0.0774; mean CPM = 7.313; SHC (Src homology 2 domain containing) transforming protein 2" ID="ID_790937152" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1102717283" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_843173630" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BRAF: 1.14-fold Down; FDR = 0.228; PValue = 0.0964; mean CPM = 24.98; v-raf murine sarcoma viral oncogene homolog B1" ID="ID_838243877" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAT: 1.44-fold Down; FDR = 0.234; PValue = 0.0996; mean CPM = 1.871; linker for activation of T cells" ID="ID_828062432" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FCGR3A: 1.84-fold Down; FDR = 0.245; PValue = 0.106; mean CPM = 1.030; Fc fragment of IgG, low affinity IIIa, receptor (CD16a)" ID="ID_180620601" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_372002198" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF10B: 1.13-fold Down; FDR = 0.343; PValue = 0.16; mean CPM = 40.59; tumor necrosis factor receptor superfamily, member 10b" ID="ID_1864583400" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MICB: 1.11-fold Down; FDR = 0.35; PValue = 0.164; mean CPM = 30.64; Macaca mulatta MHC class I polypeptide-related sequence B (MICB), mRNA." ID="ID_270939356" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MICB: 1.11-fold Down; FDR = 0.35; PValue = 0.164; mean CPM = 30.64; Macaca mulatta MHC class I polypeptide-related sequence B (MICB), mRNA." ID="ID_415544406" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1820260007" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_275596384" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_1219516545" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC1: 1.11-fold Down; FDR = 0.457; PValue = 0.23; mean CPM = 19.06; Uncharacterized protein" ID="ID_1795516861" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LCP2: 1.4-fold Up; FDR = 0.496; PValue = 0.256; mean CPM = 1.322; Uncharacterized protein" ID="ID_628901251" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP3CB: 1.08-fold Up; FDR = 0.514; PValue = 0.268; mean CPM = 76.44; protein phosphatase 3, catalytic subunit, beta isozyme" ID="ID_1280589683" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_114408345" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC3: 1.37-fold Down; FDR = 0.584; PValue = 0.318; mean CPM = 1.193; SHC-transforming protein 3; Uncharacterized protein" ID="ID_704662487" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCG: 1.47-fold Down; FDR = 0.609; PValue = 0.336; mean CPM = 0.9297; protein kinase C, gamma" ID="ID_496156250" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD247: 1.43-fold Down; FDR = 0.695; PValue = 0.404; mean CPM = 0.9076; Macaca mulatta CD247 molecule (CD247), mRNA." ID="ID_1524014774" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCB: 1.86-fold Up; FDR = 0.727; PValue = 0.43; mean CPM = 0.8705; protein kinase C, beta" ID="ID_1010384098" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNB1: 1.79-fold Up; FDR = 0.731; PValue = 0.433; mean CPM = 0.8526; interferon, beta 1, fibroblast" ID="ID_300567304" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF10A: 1.06-fold Down; FDR = 0.732; PValue = 0.434; mean CPM = 42.75; tumor necrosis factor receptor superfamily, member 10a" ID="ID_978166967" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_1618215912" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000005271: 1.36-fold Down; FDR = 0.776; PValue = 0.474; mean CPM = 0.8901; Uncharacterized protein" ID="ID_1341915048" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000005271: 1.36-fold Down; FDR = 0.776; PValue = 0.474; mean CPM = 0.8901; Uncharacterized protein" ID="ID_1541620153" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000005271: 1.36-fold Down; FDR = 0.776; PValue = 0.474; mean CPM = 0.8901; Uncharacterized protein" ID="ID_1552288403" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA6: 1.41-fold Down; FDR = 0.807; PValue = 0.504; mean CPM = 0.8019; interferon, alpha 6" ID="ID_278393745" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYROBP: 1.33-fold Up; FDR = 0.819; PValue = 0.518; mean CPM = 0.8940; TYRO protein tyrosine kinase binding protein" ID="ID_1884826111" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GZMB: 1.43-fold Up; FDR = 0.83; PValue = 0.532; mean CPM = 0.7972; granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)" ID="ID_275287913" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCR3: 1.4-fold Down; FDR = 0.832; PValue = 0.535; mean CPM = 0.8018; Natural cytotoxicity triggering receptor 3 Precursor (Natural killer cell p30-related protein)(NK-p30)(NKp30)(Activating natural killer receptor p30)(CD337 antigen)" ID="ID_386273289" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRF1: 1.75-fold Up; FDR = 0.841; PValue = 0.548; mean CPM = 0.8583; perforin 1 (pore forming protein)" ID="ID_1952340627" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICAM2: 1.26-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 0.9289; intercellular adhesion molecule 2" ID="ID_522956680" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV1: 1.25-fold Down; FDR = 0.858; PValue = 0.572; mean CPM = 0.9515; vav 1 guanine nucleotide exchange factor" ID="ID_1980887098" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZAP70: 1.25-fold Down; FDR = 0.872; PValue = 0.59; mean CPM = 0.8996; zeta-chain (TCR) associated protein kinase 70kDa" ID="ID_1742562492" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1271126423" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_1979462348" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_1749022734" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KLRC1: 1.14-fold Down; FDR = 0.903; PValue = 0.653; mean CPM = 1.817; killer cell lectin-like receptor subfamily C, member 1" ID="ID_298117754" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCR2: 1.15-fold Up; FDR = 0.906; PValue = 0.672; mean CPM = 0.7904; natural cytotoxicity triggering receptor 2" ID="ID_825633352" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ULBP1: 1.18-fold Up; FDR = 0.907; PValue = 0.675; mean CPM = 1.000; UL16 binding protein 1" ID="ID_1439853053" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA13: 1.13-fold Up; FDR = 0.908; PValue = 0.677; mean CPM = 0.7960; interferon, alpha 13" ID="ID_390186926" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA8: 1.13-fold Down; FDR = 0.911; PValue = 0.702; mean CPM = 0.7910; interferon, alpha 8" ID="ID_1101968533" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK1: 1.03-fold Down; FDR = 0.911; PValue = 0.705; mean CPM = 18.65; p21 protein (Cdc42/Rac)-activated kinase 1" ID="ID_1629716089" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FASLG: 1.2-fold Down; FDR = 0.941; PValue = 0.757; mean CPM = 0.8088; Fas ligand (TNF superfamily, member 6)" ID="ID_208640925" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AC130454.2: 1.18-fold Up; FDR = 0.942; PValue = 0.76; mean CPM = 0.8360; Calcineurin B homologous protein 2 (Hepatocellular carcinoma-associated antigen 520)" ID="ID_1969655193" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_1395122940" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC3: 1.03-fold Down; FDR = 0.952; PValue = 0.78; mean CPM = 13.31; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3" ID="ID_473011248" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA14: 1.22-fold Up; FDR = 0.965; PValue = 0.802; mean CPM = 0.8654; interferon, alpha 14" ID="ID_1589649907" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_453494672" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA4: 1.28-fold Down; FDR = 0.983; PValue = 0.829; mean CPM = 0.8584; interferon, alpha 4" ID="ID_963716888" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG2: 1.06-fold Up; FDR = 0.985; PValue = 0.834; mean CPM = 2.248; phospholipase C, gamma 2 (phosphatidylinositol-specific)" ID="ID_1384971849" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KLRK1: 1.17-fold Up; FDR = 0.995; PValue = 0.85; mean CPM = 0.8212; killer cell lectin-like receptor subfamily K, member 1" ID="ID_1314127130" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD244: 1.12-fold Up; FDR = 1; PValue = 0.874; mean CPM = 0.8195; CD244 molecule, natural killer cell receptor 2B4" ID="ID_1953484429" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAL: 1.03-fold Up; FDR = 1; PValue = 0.95; mean CPM = 1.035; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)" ID="ID_984641872" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV2: No Change; FDR = 1; PValue = 0.976; mean CPM = 25.65; vav 2 guanine nucleotide exchange factor" ID="ID_665151778" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SYK: 1.11-fold Up; FDR = 1; PValue = 0.977; mean CPM = 0.8420; spleen tyrosine kinase" ID="ID_305060199" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SH2D1B: 1.05-fold Up; FDR = 1; PValue = 0.989; mean CPM = 0.7990; SH2 domain containing 1B" ID="ID_357027334" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA1: No Change; FDR = 1; PValue = 0.998; mean CPM = 0.8014; interferon, alpha 1" ID="ID_1677039350" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KLRD1: No Change; FDR = 1; PValue = 1; mean CPM = 0.7825; Macaca mulatta killer cell lectin-like receptor subfamily D, member 1 (KLRD1), mRNA." ID="ID_1453196701" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SH2D1A: No Change; FDR = 1; PValue = 1; mean CPM = 0.7843; SH2 domain containing 1A" ID="ID_839239069" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-22: FDR = 2.96e-10, PValue = 8.23e-11" ID="ID_1417497702" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="STAT2: 2.67-fold Up; FDR = 8.02e-19; PValue = 4.03e-21; mean CPM = 185.6; signal transducer and activator of transcription 2, 113kDa" ID="ID_1280967538" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_571406550" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_794340475" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5A: 2.28-fold Up; FDR = 6.87e-14; PValue = 8.58e-16; mean CPM = 21.55; signal transducer and activator of transcription 5A" ID="ID_354182562" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_1697595455" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_837746273" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1126466417" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_154769661" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT4: 1.79-fold Up; FDR = 2.3e-05; PValue = 2.36e-06; mean CPM = 26.79; signal transducer and activator of transcription 4" ID="ID_1755779054" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS3: 1.69-fold Up; FDR = 0.000994; PValue = 0.000167; mean CPM = 37.76; suppressor of cytokine signaling 3" ID="ID_1531098149" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK3: 2.31-fold Up; FDR = 0.00186; PValue = 0.000342; mean CPM = 2.154; Janus kinase 3" ID="ID_1520726639" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYK2: 1.24-fold Down; FDR = 0.0142; PValue = 0.00354; mean CPM = 42.58; tyrosine kinase 2" ID="ID_730753399" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_660272965" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1331595732" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_67397336" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_1251957459" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1510471295" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_371060230" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL10RA: 1.55-fold Down; FDR = 0.516; PValue = 0.269; mean CPM = 0.9545; interleukin 10 receptor, alpha" ID="ID_710714261" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL22RA1: 1.26-fold Up; FDR = 0.846; PValue = 0.555; mean CPM = 0.9674; interleukin 22 receptor, alpha 1" ID="ID_48264516" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL22RA2: 1.2-fold Down; FDR = 0.899; PValue = 0.629; mean CPM = 0.7954; interleukin 22 receptor, alpha 2" ID="ID_1042109623" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL22: 1.33-fold Down; FDR = 0.928; PValue = 0.735; mean CPM = 0.8193; interleukin 22" ID="ID_217382982" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Innate immunity signaling: FDR = 5.15e-10, PValue = 1.53e-10" ID="ID_255203763" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TLR2: 8.94-fold Up; FDR = 6.97e-23; PValue = 1.25e-25; mean CPM = 18.41; toll-like receptor 2" ID="ID_1104364743" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR3: 10.3-fold Up; FDR = 1.95e-21; PValue = 5.6e-24; mean CPM = 35.70; toll-like receptor 3" ID="ID_969386388" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF7: 14.8-fold Up; FDR = 7.66e-18; PValue = 4.82e-20; mean CPM = 11.54; Macaca mulatta interferon regulatory factor 7 (IRF7), mRNA." ID="ID_1392677040" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C2: 4.8-fold Up; FDR = 3.21e-17; PValue = 2.26e-19; mean CPM = 200.3; Uncharacterized protein" ID="ID_1184767978" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK3: 3.47-fold Up; FDR = 2.3e-12; PValue = 4.07e-14; mean CPM = 12.05; receptor-interacting serine-threonine kinase 3" ID="ID_1711729580" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LY96: 3.13-fold Up; FDR = 1.27e-10; PValue = 3.43e-12; mean CPM = 6.127; lymphocyte antigen 96" ID="ID_1638290594" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR4: 3.45-fold Up; FDR = 3.1e-09; PValue = 1.19e-10; mean CPM = 7.456; Macaca mulatta toll-like receptor 4 (TLR4), mRNA." ID="ID_1666014706" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_1242868106" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DUSP7: 1.77-fold Down; FDR = 3.08e-08; PValue = 1.52e-09; mean CPM = 22.67; dual specificity phosphatase 7" ID="ID_1214444371" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK4: 1.8-fold Up; FDR = 3.31e-08; PValue = 1.64e-09; mean CPM = 12.89; interleukin-1 receptor-associated kinase 4" ID="ID_308410274" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1008206476" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD14: 2.75-fold Down; FDR = 6.54e-07; PValue = 4.46e-08; mean CPM = 5.195; CD14 molecule" ID="ID_1833877779" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_844608052" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF1: 1.51-fold Up; FDR = 5.28e-06; PValue = 4.58e-07; mean CPM = 22.13; activating transcription factor 1" ID="ID_1745107332" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K3: 1.45-fold Down; FDR = 7.01e-06; PValue = 6.34e-07; mean CPM = 180.1; mitogen-activated protein kinase kinase 3" ID="ID_608466863" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA5: 3.28-fold Up; FDR = 1.4e-05; PValue = 1.36e-06; mean CPM = 2.288; ribosomal protein S6 kinase, 90kDa, polypeptide 5" ID="ID_1308754175" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1691617899" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R1B: 1.39-fold Down; FDR = 4.37e-05; PValue = 4.86e-06; mean CPM = 233.1; protein phosphatase 2, regulatory subunit A, beta" ID="ID_313191112" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_1479298070" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP2: 1.45-fold Up; FDR = 0.000179; PValue = 2.4e-05; mean CPM = 65.31; TGF-beta activated kinase 1/MAP3K7 binding protein 2" ID="ID_817150859" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2CB: 1.35-fold Up; FDR = 0.000215; PValue = 2.96e-05; mean CPM = 59.68; protein phosphatase 2, catalytic subunit, beta isozyme" ID="ID_119971376" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP3: 1.5-fold Up; FDR = 0.000276; PValue = 3.92e-05; mean CPM = 11.67; TGF-beta activated kinase 1/MAP3K7 binding protein 3" ID="ID_235469173" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF2: 1.34-fold Up; FDR = 0.000403; PValue = 6.01e-05; mean CPM = 39.83; activating transcription factor 2" ID="ID_1170992658" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_1894350078" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBK1: 1.3-fold Up; FDR = 0.00337; PValue = 0.000674; mean CPM = 30.46; TANK-binding kinase 1" ID="ID_1365479919" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R5D: 1.27-fold Down; FDR = 0.00482; PValue = 0.00101; mean CPM = 35.61; protein phosphatase 2, regulatory subunit B', delta" ID="ID_387281442" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_716255241" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_312874500" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK3: 1.54-fold Up; FDR = 0.00653; PValue = 0.00144; mean CPM = 19.97; interleukin-1 receptor-associated kinase 3" ID="ID_934123150" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR5: 1.86-fold Down; FDR = 0.00878; PValue = 0.00203; mean CPM = 3.008; toll-like receptor 5" ID="ID_129492554" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DUSP3: 1.27-fold Down; FDR = 0.0115; PValue = 0.00274; mean CPM = 24.56; dual specificity phosphatase 3" ID="ID_259953173" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1254981404" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C5: 2.29-fold Up; FDR = 0.0212; PValue = 0.00561; mean CPM = 1.418; complement component 5" ID="ID_1926360075" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="UBB: 1.22-fold Up; FDR = 0.0235; PValue = 0.00634; mean CPM = 526.7; ubiquitin B" ID="ID_1024675559" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA1: 1.25-fold Down; FDR = 0.0241; PValue = 0.00652; mean CPM = 21.28; ribosomal protein S6 kinase, 90kDa, polypeptide 1" ID="ID_1732793376" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_1899152743" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB1: 1.21-fold Up; FDR = 0.0313; PValue = 0.00884; mean CPM = 36.07; cAMP responsive element binding protein 1" ID="ID_284951725" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ECSIT: 1.2-fold Down; FDR = 0.0358; PValue = 0.0104; mean CPM = 54.27; ECSIT homolog (Drosophila)" ID="ID_723729845" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1051044747" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPKAPK3: 1.18-fold Up; FDR = 0.0689; PValue = 0.0225; mean CPM = 35.42; mitogen-activated protein kinase-activated protein kinase 3" ID="ID_247226989" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C1QB: 2.62-fold Up; FDR = 0.0887; PValue = 0.0304; mean CPM = 1.092; complement component 1, q subcomponent, B chain" ID="ID_701440987" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_917993591" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_814513807" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DUSP6: 1.22-fold Up; FDR = 0.131; PValue = 0.0487; mean CPM = 91.01; dual specificity phosphatase 6" ID="ID_624154845" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_598453861" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EEA1: 1.14-fold Down; FDR = 0.167; PValue = 0.0656; mean CPM = 69.68; early endosome antigen 1" ID="ID_1905071295" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DUSP4: 1.28-fold Down; FDR = 0.199; PValue = 0.0817; mean CPM = 66.70; dual specificity phosphatase 4" ID="ID_199232038" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C1QC: 2.02-fold Up; FDR = 0.203; PValue = 0.0839; mean CPM = 1.322; complement component 1, q subcomponent, C chain" ID="ID_377845999" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MASP1: 1.46-fold Down; FDR = 0.264; PValue = 0.115; mean CPM = 4.467; mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)" ID="ID_1543970694" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP1: 1.12-fold Down; FDR = 0.351; PValue = 0.165; mean CPM = 17.96; TGF-beta activated kinase 1/MAP3K7 binding protein 1" ID="ID_863495602" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MEF2C: 1.24-fold Down; FDR = 0.357; PValue = 0.168; mean CPM = 6.816; myocyte enhancer factor 2C" ID="ID_1592127916" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C8B: 2.74-fold Up; FDR = 0.396; PValue = 0.192; mean CPM = 0.8553; complement component 8, beta polypeptide" ID="ID_1896158067" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TICAM1: 1.11-fold Down; FDR = 0.398; PValue = 0.192; mean CPM = 26.73; toll-like receptor adaptor molecule 1" ID="ID_770629632" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_1162964508" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_823622798" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SIGIRR: 1.29-fold Up; FDR = 0.437; PValue = 0.217; mean CPM = 2.330; single immunoglobulin and toll-interleukin 1 receptor (TIR) domain" ID="ID_1336145714" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1606656414" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C9: 1.41-fold Up; FDR = 0.505; PValue = 0.262; mean CPM = 1.295; complement component 9" ID="ID_522241169" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MASP2: 1.23-fold Down; FDR = 0.546; PValue = 0.291; mean CPM = 3.073; mannan-binding lectin serine peptidase 2" ID="ID_1634083444" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000000985: 1.2-fold Up; FDR = 0.569; PValue = 0.307; mean CPM = 11.32; Uncharacterized protein" ID="ID_212869023" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LBP: 1.52-fold Down; FDR = 0.591; PValue = 0.324; mean CPM = 0.8819; lipopolysaccharide binding protein" ID="ID_1191790338" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPKAPK2: 1.06-fold Down; FDR = 0.733; PValue = 0.435; mean CPM = 82.16; mitogen-activated protein kinase-activated protein kinase 2" ID="ID_1136148156" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2CA: 1.05-fold Up; FDR = 0.8; PValue = 0.497; mean CPM = 62.78; protein phosphatase 2, catalytic subunit, alpha isozyme" ID="ID_1440860827" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR6: 1.07-fold Down; FDR = 0.84; PValue = 0.546; mean CPM = 7.909; toll-like receptor 6" ID="ID_1269672589" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TIRAP: 1.07-fold Up; FDR = 0.841; PValue = 0.548; mean CPM = 8.693; Macaca mulatta toll-interleukin 1 receptor (TIR) domain containing adaptor protein (TIRAP), mRNA." ID="ID_189328815" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MBL2: 1.3-fold Up; FDR = 0.85; PValue = 0.561; mean CPM = 0.7954; mannose-binding lectin (protein C) 2, soluble (opsonic defect)" ID="ID_48528365" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C6: 1.72-fold Down; FDR = 0.856; PValue = 0.57; mean CPM = 0.8334; complement component 6" ID="ID_950974970" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1028425784" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD180: 1.69-fold Down; FDR = 0.868; PValue = 0.585; mean CPM = 0.8488; CD180 molecule" ID="ID_1425409490" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1317745519" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR7: 1.37-fold Down; FDR = 0.878; PValue = 0.597; mean CPM = 0.8402; toll-like receptor 7" ID="ID_238886315" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK1: 1.04-fold Down; FDR = 0.885; PValue = 0.606; mean CPM = 41.54; interleukin-1 receptor-associated kinase 1" ID="ID_2547214" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK7: 1.04-fold Down; FDR = 0.899; PValue = 0.632; mean CPM = 16.93; Uncharacterized protein" ID="ID_126546450" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LY86: 1.16-fold Down; FDR = 0.903; PValue = 0.649; mean CPM = 0.7948; lymphocyte antigen 86" ID="ID_760149228" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR10: 1.28-fold Down; FDR = 0.915; PValue = 0.715; mean CPM = 0.8713; toll-like receptor 10" ID="ID_1119042469" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKE: 1.03-fold Up; FDR = 0.929; PValue = 0.737; mean CPM = 21.61; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon" ID="ID_1660495446" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZFYVE20: 1.02-fold Down; FDR = 0.937; PValue = 0.75; mean CPM = 48.41; zinc finger, FYVE domain containing 20" ID="ID_1745763163" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C8A: 1.06-fold Up; FDR = 0.968; PValue = 0.808; mean CPM = 0.8260; complement component 8, alpha polypeptide" ID="ID_1658683157" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_1638878889" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C8G: 1.15-fold Up; FDR = 0.978; PValue = 0.822; mean CPM = 0.8664; complement component 8, gamma polypeptide" ID="ID_1704869334" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA3: 1.02-fold Up; FDR = 0.982; PValue = 0.829; mean CPM = 58.16; ribosomal protein S6 kinase, 90kDa, polypeptide 3" ID="ID_1624720534" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_870437454" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR9: 1.01-fold Down; FDR = 1; PValue = 0.859; mean CPM = 21.45; Macaca mulatta toll-like receptor 9 (TLR9), mRNA." ID="ID_346425864" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C7: 1.11-fold Up; FDR = 1; PValue = 0.883; mean CPM = 0.8197; complement component 7" ID="ID_601776269" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R4: 1.01-fold Down; FDR = 1; PValue = 0.913; mean CPM = 41.33; phosphoinositide-3-kinase, regulatory subunit 4" ID="ID_676878009" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR1: 1.02-fold Up; FDR = 1; PValue = 0.945; mean CPM = 1.221; toll-like receptor 1" ID="ID_333626193" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_1953688881" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-4 : FDR = 6.36e-10, PValue = 2.01e-10" ID="ID_38318657" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_1895798266" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1542635595" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5A: 2.28-fold Up; FDR = 6.87e-14; PValue = 8.58e-16; mean CPM = 21.55; signal transducer and activator of transcription 5A" ID="ID_925604231" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_230411168" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_782976262" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRS1: 2.78-fold Up; FDR = 7.67e-09; PValue = 3.19e-10; mean CPM = 26.55; Uncharacterized protein" ID="ID_1909283902" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1963253809" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_711078911" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1696578125" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_478474926" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS5: 1.38-fold Up; FDR = 4.45e-05; PValue = 4.96e-06; mean CPM = 88.27; suppressor of cytokine signaling 5" ID="ID_362307733" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF2: 1.34-fold Up; FDR = 0.000403; PValue = 6.01e-05; mean CPM = 39.83; activating transcription factor 2" ID="ID_618177854" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAD: 1.36-fold Down; FDR = 0.000605; PValue = 9.52e-05; mean CPM = 48.46; BCL2-associated agonist of cell death" ID="ID_1817262606" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GATA3: 2.81-fold Up; FDR = 0.000734; PValue = 0.000119; mean CPM = 2.229; GATA binding protein 3" ID="ID_538468524" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS3: 1.69-fold Up; FDR = 0.000994; PValue = 0.000167; mean CPM = 37.76; suppressor of cytokine signaling 3" ID="ID_1909303233" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFIL3: 1.37-fold Up; FDR = 0.00114; PValue = 0.000196; mean CPM = 50.42; nuclear factor, interleukin 3 regulated" ID="ID_1873061778" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK3: 2.31-fold Up; FDR = 0.00186; PValue = 0.000342; mean CPM = 2.154; Janus kinase 3" ID="ID_367354217" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GAB2: 1.33-fold Down; FDR = 0.00208; PValue = 0.000387; mean CPM = 22.59; GRB2-associated binding protein 2" ID="ID_285327265" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_12805742" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FES: 1.34-fold Up; FDR = 0.00677; PValue = 0.0015; mean CPM = 22.71; feline sarcoma oncogene" ID="ID_1387496994" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYK2: 1.24-fold Down; FDR = 0.0142; PValue = 0.00354; mean CPM = 42.58; tyrosine kinase 2" ID="ID_1086869443" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_617859536" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DOK2: 1.76-fold Down; FDR = 0.0214; PValue = 0.00569; mean CPM = 2.236; docking protein 2, 56kDa" ID="ID_1885928683" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_143149674" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INPP5D: 1.88-fold Down; FDR = 0.0276; PValue = 0.00763; mean CPM = 5.690; inositol polyphosphate-5-phosphatase, 145kDa" ID="ID_280656993" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_639740826" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1056881923" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT6: 1.18-fold Up; FDR = 0.0727; PValue = 0.024; mean CPM = 217.5; signal transducer and activator of transcription 6, interleukin-4 induced" ID="ID_1638389262" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_575480802" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_1120343574" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC5: 1.51-fold Down; FDR = 0.134; PValue = 0.0501; mean CPM = 18.55; Baculoviral IAP repeat-containing protein 5 isoform 1; Uncharacterized protein" ID="ID_1913157563" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1283554299" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_1775563206" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EP300: 1.11-fold Up; FDR = 0.312; PValue = 0.142; mean CPM = 162.8; E1A binding protein p300" ID="ID_503534411" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_177321945" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1077253761" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1624819385" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_526101149" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRH1: 1.25-fold Up; FDR = 0.455; PValue = 0.228; mean CPM = 4.779; histamine receptor H1" ID="ID_1813493000" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL4R: 1.05-fold Down; FDR = 0.803; PValue = 0.499; mean CPM = 193.5; interleukin 4 receptor" ID="ID_195398398" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CBL: 1.05-fold Down; FDR = 0.824; PValue = 0.524; mean CPM = 51.06; Cas-Br-M (murine) ecotropic retroviral transforming sequence" ID="ID_56063252" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_189566522" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB1: 1.04-fold Up; FDR = 0.88; PValue = 0.6; mean CPM = 30.80; Uncharacterized protein" ID="ID_836346576" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL4: 1.27-fold Down; FDR = 0.933; PValue = 0.745; mean CPM = 0.8077; interleukin 4" ID="ID_797721163" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="B7.1 / B7.2 (CD80 CD86) CD28: FDR = 6.36e-10, PValue = 2.12e-10" ID="ID_1029534327" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="HLA-DMB: 17.5-fold Up; FDR = 2.77e-15; PValue = 2.66e-17; mean CPM = 9.464; HLA class II histocompatibility antigen, DM beta chain Precursor (MHC class II antigen DMB)(Really interesting new gene 7 protein)" ID="ID_328919044" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DPA1: 107-fold Up; FDR = 5.97e-15; PValue = 6.11e-17; mean CPM = 17.08; HLA class II histocompatibility antigen, DP alpha 1 chain Precursor (HLA-SB alpha chain)(MHC class II DP3-alpha)(DP(W3))(DP(W4))" ID="ID_1046793783" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DQB1: 31.1-fold Up; FDR = 6.93e-13; PValue = 1.1e-14; mean CPM = 6.675; Macaca mulatta MHC class II antigen (MAMU-DRB), mRNA." ID="ID_115448744" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC4: 1.85-fold Down; FDR = 1.13e-11; PValue = 2.37e-13; mean CPM = 51.58; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4" ID="ID_905622748" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA1: 15.1-fold Up; FDR = 1.9e-08; PValue = 8.86e-10; mean CPM = 3.665; HLA class II histocompatibility antigen, DQ alpha 1 chain precursor" ID="ID_1647117864" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DPB1: 7.73-fold Up; FDR = 4.73e-08; PValue = 2.45e-09; mean CPM = 1.528; Macaca mulatta major histocompatibility complex, class II, DP beta (MAMU-DPB), mRNA." ID="ID_1628474860" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1501414854" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1199013440" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_1406067463" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1467804826" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL10: 1.55-fold Up; FDR = 5.92e-06; PValue = 5.22e-07; mean CPM = 21.83; B-cell CLL/lymphoma 10" ID="ID_667633175" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_161796183" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_1683956084" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPRC: 6.08-fold Up; FDR = 0.000285; PValue = 4.07e-05; mean CPM = 1.220; protein tyrosine phosphatase, receptor type, C" ID="ID_394124566" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC2: 4.03-fold Down; FDR = 0.000346; PValue = 5.06e-05; mean CPM = 1.347; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2" ID="ID_531367979" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_1721782837" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG1: 1.31-fold Down; FDR = 0.00352; PValue = 0.000707; mean CPM = 53.66; phospholipase C, gamma 1" ID="ID_1327315000" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1711443545" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FYN: 1.22-fold Up; FDR = 0.0156; PValue = 0.00393; mean CPM = 92.94; FYN oncogene related to SRC, FGR, YES" ID="ID_98417236" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CARD11: 1.31-fold Down; FDR = 0.0223; PValue = 0.00597; mean CPM = 58.32; caspase recruitment domain family, member 11" ID="ID_1589178247" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBID: 1.47-fold Down; FDR = 0.0247; PValue = 0.0067; mean CPM = 6.446; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta" ID="ID_571975263" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1848580563" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIE: 1.3-fold Down; FDR = 0.0272; PValue = 0.00752; mean CPM = 16.93; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon" ID="ID_321706739" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFAT5: 1.21-fold Up; FDR = 0.0273; PValue = 0.00754; mean CPM = 113.0; nuclear factor of activated T-cells 5, tonicity-responsive" ID="ID_1772037675" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_291747032" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SIKE1: 1.21-fold Up; FDR = 0.0353; PValue = 0.0102; mean CPM = 31.55; suppressor of IKBKE 1" ID="ID_1805300489" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1680352481" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKAP: 1.19-fold Down; FDR = 0.0434; PValue = 0.013; mean CPM = 50.22; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein" ID="ID_1277157499" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DAG1: 1.54-fold Down; FDR = 0.0661; PValue = 0.0214; mean CPM = 3.013; dystroglycan 1 (dystrophin-associated glycoprotein 1)" ID="ID_489102635" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DOA: 2.74-fold Up; FDR = 0.0694; PValue = 0.0227; mean CPM = 0.9089; HLA class II histocompatibility antigen, DO alpha chain Precursor (MHC class II antigen DOA)(MHC DZ alpha)(MHC DN-alpha)" ID="ID_1281569351" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIZ: 1.23-fold Up; FDR = 0.0949; PValue = 0.033; mean CPM = 91.08; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta" ID="ID_1699865785" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_958161079" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_765021541" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITPR3: 1.13-fold Up; FDR = 0.194; PValue = 0.079; mean CPM = 157.4; inositol 1,4,5-triphosphate receptor, type 3" ID="ID_1926079647" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_897072733" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAT: 1.44-fold Down; FDR = 0.234; PValue = 0.0996; mean CPM = 1.871; linker for activation of T cells" ID="ID_1269304077" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_1145404954" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MALT1: 1.11-fold Down; FDR = 0.35; PValue = 0.164; mean CPM = 42.89; mucosa associated lymphoid tissue lymphoma translocation gene 1" ID="ID_1339337656" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014796: 1.77-fold Up; FDR = 0.381; PValue = 0.182; mean CPM = 0.9085; Uncharacterized protein" ID="ID_1269365573" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_69887335" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACTR2: 1.09-fold Up; FDR = 0.44; PValue = 0.219; mean CPM = 263.8; ARP2 actin-related protein 2 homolog (yeast)" ID="ID_441587872" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC1: 1.11-fold Down; FDR = 0.457; PValue = 0.23; mean CPM = 19.06; Uncharacterized protein" ID="ID_1648035692" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LCP2: 1.4-fold Up; FDR = 0.496; PValue = 0.256; mean CPM = 1.322; Uncharacterized protein" ID="ID_1968931598" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCQ: 1.56-fold Up; FDR = 0.522; PValue = 0.274; mean CPM = 1.047; Uncharacterized protein" ID="ID_696814726" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_1669031232" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDC42: 1.07-fold Down; FDR = 0.608; PValue = 0.335; mean CPM = 91.67; cell division cycle 42" ID="ID_1443009242" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSK: 1.06-fold Down; FDR = 0.673; PValue = 0.386; mean CPM = 45.36; c-src tyrosine kinase" ID="ID_986728552" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD247: 1.43-fold Down; FDR = 0.695; PValue = 0.404; mean CPM = 0.9076; Macaca mulatta CD247 molecule (CD247), mRNA." ID="ID_381782576" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRAP2: 1.31-fold Up; FDR = 0.701; PValue = 0.408; mean CPM = 3.696; GRB2-related adaptor protein 2" ID="ID_30348017" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC2IP: 1.08-fold Down; FDR = 0.746; PValue = 0.446; mean CPM = 11.08; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein" ID="ID_988905935" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WAS: 1.37-fold Down; FDR = 0.771; PValue = 0.469; mean CPM = 0.9085; Wiskott-Aldrich syndrome" ID="ID_952625378" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD4: 1.27-fold Up; FDR = 0.807; PValue = 0.503; mean CPM = 1.122; CD4 molecule" ID="ID_1255772943" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTLA4: 1.41-fold Down; FDR = 0.827; PValue = 0.527; mean CPM = 0.8017; cytotoxic T-lymphocyte-associated protein 4" ID="ID_1611145255" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_295073161" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV1: 1.25-fold Down; FDR = 0.858; PValue = 0.572; mean CPM = 0.9515; vav 1 guanine nucleotide exchange factor" ID="ID_1264591080" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZAP70: 1.25-fold Down; FDR = 0.872; PValue = 0.59; mean CPM = 0.8996; zeta-chain (TCR) associated protein kinase 70kDa" ID="ID_1247871740" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_210626379" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DRB: 1.28-fold Up; FDR = 0.898; PValue = 0.624; mean CPM = 0.8112; MHC class II antigen; Uncharacterized protein" ID="ID_1636259762" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NR0B2: 1.24-fold Down; FDR = 0.899; PValue = 0.635; mean CPM = 0.7887; nuclear receptor subfamily 0, group B, member 2" ID="ID_820760081" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3D: 1.22-fold Down; FDR = 0.903; PValue = 0.641; mean CPM = 0.7953; CD3d molecule, delta (CD3-TCR complex)" ID="ID_1697977292" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACTR3: 1.13-fold Up; FDR = 0.908; PValue = 0.681; mean CPM = 0.7943; ARP3 actin-related protein 3 homolog (yeast)" ID="ID_766105767" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA2: 1.13-fold Up; FDR = 0.908; PValue = 0.681; mean CPM = 0.7877; HLA class II histocompatibility antigen, DQ alpha 2 chain Precursor (HLA class II histocompatibility antigen, DQ(6) alpha chain)(DX alpha chain)(HLA-DQA1)" ID="ID_1080619626" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK1: 1.03-fold Down; FDR = 0.911; PValue = 0.705; mean CPM = 18.65; p21 protein (Cdc42/Rac)-activated kinase 1" ID="ID_805283673" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKE: 1.03-fold Up; FDR = 0.929; PValue = 0.737; mean CPM = 21.61; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon" ID="ID_1884134762" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC3: 1.03-fold Down; FDR = 0.952; PValue = 0.78; mean CPM = 13.31; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3" ID="ID_481403259" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_1653849836" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD80: 1.08-fold Up; FDR = 0.971; PValue = 0.812; mean CPM = 1.157; CD80 molecule" ID="ID_805500806" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITK: 1.07-fold Up; FDR = 1; PValue = 0.871; mean CPM = 0.9033; IL2-inducible T-cell kinase" ID="ID_287866255" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_1835758124" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3G: 1.03-fold Up; FDR = 1; PValue = 0.977; mean CPM = 0.8190; CD3g molecule, gamma (CD3-TCR complex)" ID="ID_1777251551" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SYK: 1.11-fold Up; FDR = 1; PValue = 0.977; mean CPM = 0.8420; spleen tyrosine kinase" ID="ID_651058091" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3E: 1.07-fold Down; FDR = 1; PValue = 0.981; mean CPM = 0.7994; Uncharacterized protein" ID="ID_1700888865" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD86: 1.01-fold Down; FDR = 1; PValue = 0.99; mean CPM = 0.8012; CD86 molecule" ID="ID_1885025692" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2: 1.03-fold Up; FDR = 1; PValue = 0.998; mean CPM = 0.7974; interleukin 2" ID="ID_1545307195" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="CTLA4: FDR = 6.68e-10, PValue = 2.35e-10" ID="ID_1967171530" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_1960397093" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DMB: 17.5-fold Up; FDR = 2.77e-15; PValue = 2.66e-17; mean CPM = 9.464; HLA class II histocompatibility antigen, DM beta chain Precursor (MHC class II antigen DMB)(Really interesting new gene 7 protein)" ID="ID_562211733" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DPA1: 107-fold Up; FDR = 5.97e-15; PValue = 6.11e-17; mean CPM = 17.08; HLA class II histocompatibility antigen, DP alpha 1 chain Precursor (HLA-SB alpha chain)(MHC class II DP3-alpha)(DP(W3))(DP(W4))" ID="ID_521946070" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DQB1: 31.1-fold Up; FDR = 6.93e-13; PValue = 1.1e-14; mean CPM = 6.675; Macaca mulatta MHC class II antigen (MAMU-DRB), mRNA." ID="ID_1741829012" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA1: 15.1-fold Up; FDR = 1.9e-08; PValue = 8.86e-10; mean CPM = 3.665; HLA class II histocompatibility antigen, DQ alpha 1 chain precursor" ID="ID_1178289507" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DPB1: 7.73-fold Up; FDR = 4.73e-08; PValue = 2.45e-09; mean CPM = 1.528; Macaca mulatta major histocompatibility complex, class II, DP beta (MAMU-DPB), mRNA." ID="ID_1451980894" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1641102987" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_1227944269" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG1: 1.31-fold Down; FDR = 0.00352; PValue = 0.000707; mean CPM = 53.66; phospholipase C, gamma 1" ID="ID_475692693" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AP2B1: 1.25-fold Up; FDR = 0.00795; PValue = 0.0018; mean CPM = 199.8; adaptor-related protein complex 2, beta 1 subunit" ID="ID_1987140464" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FYN: 1.22-fold Up; FDR = 0.0156; PValue = 0.00393; mean CPM = 92.94; FYN oncogene related to SRC, FGR, YES" ID="ID_78522629" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_133419211" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DOA: 2.74-fold Up; FDR = 0.0694; PValue = 0.0227; mean CPM = 0.9089; HLA class II histocompatibility antigen, DO alpha chain Precursor (MHC class II antigen DOA)(MHC DZ alpha)(MHC DN-alpha)" ID="ID_811502155" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1903209005" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_999952541" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN22: 1.76-fold Down; FDR = 0.209; PValue = 0.0864; mean CPM = 1.477; protein tyrosine phosphatase, non-receptor type 22 (lymphoid)" ID="ID_1241117761" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AP2S1: 1.13-fold Down; FDR = 0.213; PValue = 0.0887; mean CPM = 107.4; adaptor-related protein complex 2, sigma 1 subunit" ID="ID_1662435374" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAT: 1.44-fold Down; FDR = 0.234; PValue = 0.0996; mean CPM = 1.871; linker for activation of T cells" ID="ID_1289124366" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_319228124" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AP2A2: 1.11-fold Down; FDR = 0.296; PValue = 0.133; mean CPM = 69.59; adaptor-related protein complex 2, alpha 2 subunit" ID="ID_544353313" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_1607913133" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014796: 1.77-fold Up; FDR = 0.381; PValue = 0.182; mean CPM = 0.9085; Uncharacterized protein" ID="ID_1839991483" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1275613371" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_471772762" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LCP2: 1.4-fold Up; FDR = 0.496; PValue = 0.256; mean CPM = 1.322; Uncharacterized protein" ID="ID_912145286" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_196031037" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD247: 1.43-fold Down; FDR = 0.695; PValue = 0.404; mean CPM = 0.9076; Macaca mulatta CD247 molecule (CD247), mRNA." ID="ID_1320815887" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRAP2: 1.31-fold Up; FDR = 0.701; PValue = 0.408; mean CPM = 3.696; GRB2-related adaptor protein 2" ID="ID_921926990" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD4: 1.27-fold Up; FDR = 0.807; PValue = 0.503; mean CPM = 1.122; CD4 molecule" ID="ID_717417231" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTLA4: 1.41-fold Down; FDR = 0.827; PValue = 0.527; mean CPM = 0.8017; cytotoxic T-lymphocyte-associated protein 4" ID="ID_30776544" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZAP70: 1.25-fold Down; FDR = 0.872; PValue = 0.59; mean CPM = 0.8996; zeta-chain (TCR) associated protein kinase 70kDa" ID="ID_416270340" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DRB: 1.28-fold Up; FDR = 0.898; PValue = 0.624; mean CPM = 0.8112; MHC class II antigen; Uncharacterized protein" ID="ID_1169227969" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3D: 1.22-fold Down; FDR = 0.903; PValue = 0.641; mean CPM = 0.7953; CD3d molecule, delta (CD3-TCR complex)" ID="ID_758846719" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA2: 1.13-fold Up; FDR = 0.908; PValue = 0.681; mean CPM = 0.7877; HLA class II histocompatibility antigen, DQ alpha 2 chain Precursor (HLA class II histocompatibility antigen, DQ(6) alpha chain)(DX alpha chain)(HLA-DQA1)" ID="ID_1988597076" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICOSLG: 1.07-fold Down; FDR = 0.909; PValue = 0.684; mean CPM = 6.739; inducible T-cell co-stimulator ligand" ID="ID_710049222" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAT1: 1.13-fold Down; FDR = 0.911; PValue = 0.702; mean CPM = 0.7899; T cell receptor associated transmembrane adaptor 1" ID="ID_341963323" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICOS: 1.19-fold Up; FDR = 0.931; PValue = 0.741; mean CPM = 0.8158; Uncharacterized protein" ID="ID_1920961013" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R4: 1.02-fold Down; FDR = 0.943; PValue = 0.763; mean CPM = 93.45; protein phosphatase 2A activator, regulatory subunit 4" ID="ID_1535899100" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD80: 1.08-fold Up; FDR = 0.971; PValue = 0.812; mean CPM = 1.157; CD80 molecule" ID="ID_1256570098" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITK: 1.07-fold Up; FDR = 1; PValue = 0.871; mean CPM = 0.9033; IL2-inducible T-cell kinase" ID="ID_1553412101" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3G: 1.03-fold Up; FDR = 1; PValue = 0.977; mean CPM = 0.8190; CD3g molecule, gamma (CD3-TCR complex)" ID="ID_101565380" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SYK: 1.11-fold Up; FDR = 1; PValue = 0.977; mean CPM = 0.8420; spleen tyrosine kinase" ID="ID_660661686" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3E: 1.07-fold Down; FDR = 1; PValue = 0.981; mean CPM = 0.7994; Uncharacterized protein" ID="ID_1276003160" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD86: 1.01-fold Down; FDR = 1; PValue = 0.99; mean CPM = 0.8012; CD86 molecule" ID="ID_612329722" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2: 1.03-fold Up; FDR = 1; PValue = 0.998; mean CPM = 0.7974; interleukin 2" ID="ID_234740331" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-9: FDR = 7.37e-10, PValue = 2.73e-10" ID="ID_361789799" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="STAT2: 2.67-fold Up; FDR = 8.02e-19; PValue = 4.03e-21; mean CPM = 185.6; signal transducer and activator of transcription 2, 113kDa" ID="ID_1216330055" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_745135153" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5A: 2.28-fold Up; FDR = 6.87e-14; PValue = 8.58e-16; mean CPM = 21.55; signal transducer and activator of transcription 5A" ID="ID_440990887" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_1159170289" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_633211432" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_430411613" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_704160161" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1B: 2.24-fold Up; FDR = 2.68e-06; PValue = 2.16e-07; mean CPM = 19.44; tumor necrosis factor receptor superfamily, member 1B" ID="ID_480528893" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_1005738840" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1964218752" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT4: 1.79-fold Up; FDR = 2.3e-05; PValue = 2.36e-06; mean CPM = 26.79; signal transducer and activator of transcription 4" ID="ID_42369418" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS5: 1.38-fold Up; FDR = 4.45e-05; PValue = 4.96e-06; mean CPM = 88.27; suppressor of cytokine signaling 5" ID="ID_1327075795" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_139299499" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS3: 1.69-fold Up; FDR = 0.000994; PValue = 0.000167; mean CPM = 37.76; suppressor of cytokine signaling 3" ID="ID_1515430611" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CISH: 1.95-fold Up; FDR = 0.00116; PValue = 0.0002; mean CPM = 5.083; cytokine inducible SH2-containing protein" ID="ID_1870609433" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK3: 2.31-fold Up; FDR = 0.00186; PValue = 0.000342; mean CPM = 2.154; Janus kinase 3" ID="ID_947515733" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="REL: 1.46-fold Down; FDR = 0.00272; PValue = 0.000526; mean CPM = 10.17; v-rel avian reticuloendotheliosis viral oncogene homolog" ID="ID_1671269046" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS2: 1.31-fold Down; FDR = 0.0188; PValue = 0.0049; mean CPM = 35.29; suppressor of cytokine signaling 2" ID="ID_792034507" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_15126102" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1689593474" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL3: 1.25-fold Up; FDR = 0.0559; PValue = 0.0175; mean CPM = 16.96; B-cell CLL/lymphoma 3" ID="ID_500791186" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELB: 1.22-fold Down; FDR = 0.0606; PValue = 0.0193; mean CPM = 26.64; v-rel reticuloendotheliosis viral oncogene homolog B" ID="ID_495221945" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_451540063" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_140895982" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS6: 1.13-fold Up; FDR = 0.248; PValue = 0.107; mean CPM = 30.93; suppressor of cytokine signaling 6" ID="ID_1488233768" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1A: 1.11-fold Up; FDR = 0.297; PValue = 0.134; mean CPM = 134.7; tumor necrosis factor receptor superfamily, member 1A" ID="ID_1602352295" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_533853744" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1003721153" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3C2B: 1.17-fold Down; FDR = 0.406; PValue = 0.198; mean CPM = 6.381; phosphoinositide-3-kinase, class 2, beta polypeptide" ID="ID_1299770532" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1063308168" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_374547263" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL9R: 2.21-fold Down; FDR = 0.63; PValue = 0.352; mean CPM = 0.8661; interleukin 9 receptor" ID="ID_64769870" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_586928025" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_1995085189" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL9: 1.14-fold Up; FDR = 0.911; PValue = 0.705; mean CPM = 0.7910; interleukin 9" ID="ID_749474615" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK9: 1.02-fold Down; FDR = 0.942; PValue = 0.76; mean CPM = 37.82; cyclin-dependent kinase 9" ID="ID_1077231811" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3C2A: 1.02-fold Up; FDR = 0.957; PValue = 0.788; mean CPM = 84.41; phosphoinositide-3-kinase, class 2, alpha polypeptide" ID="ID_866182035" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R4: 1.01-fold Down; FDR = 1; PValue = 0.913; mean CPM = 41.33; phosphoinositide-3-kinase, regulatory subunit 4" ID="ID_160001507" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="p38: FDR = 1.02e-09, PValue = 3.95e-10" ID="ID_137718122" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1993208078" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_31138241" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MEF2D: 1.73-fold Down; FDR = 2.02e-08; PValue = 9.5e-10; mean CPM = 61.43; myocyte enhancer factor 2D" ID="ID_1916431095" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DDIT3: 2.05-fold Up; FDR = 1.46e-06; PValue = 1.09e-07; mean CPM = 45.52; DNA-damage-inducible transcript 3" ID="ID_1615319622" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA5: 3.28-fold Up; FDR = 1.4e-05; PValue = 1.36e-06; mean CPM = 2.288; ribosomal protein S6 kinase, 90kDa, polypeptide 5" ID="ID_1787406955" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF2: 1.34-fold Up; FDR = 0.000403; PValue = 6.01e-05; mean CPM = 39.83; activating transcription factor 2" ID="ID_1864912556" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_1319704517" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAX: 1.28-fold Up; FDR = 0.00569; PValue = 0.00123; mean CPM = 29.78; MYC associated factor X" ID="ID_774317542" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB1: 1.21-fold Up; FDR = 0.0313; PValue = 0.00884; mean CPM = 36.07; cAMP responsive element binding protein 1" ID="ID_1040472718" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRADD: 1.22-fold Up; FDR = 0.0319; PValue = 0.00907; mean CPM = 34.75; TNFRSF1A-associated via death domain" ID="ID_832298021" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFBR1: 1.2-fold Up; FDR = 0.037; PValue = 0.0108; mean CPM = 90.92; transforming growth factor, beta receptor 1" ID="ID_1788521785" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_1821106628" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_277434218" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MKNK1: 1.27-fold Down; FDR = 0.0706; PValue = 0.0232; mean CPM = 9.169; MAP kinase interacting serine/threonine kinase 1" ID="ID_214091582" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K9: 1.62-fold Down; FDR = 0.177; PValue = 0.0705; mean CPM = 1.806; mitogen-activated protein kinase kinase kinase 9" ID="ID_406938881" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1396487837" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_1048581230" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPKAPK5: 1.15-fold Down; FDR = 0.297; PValue = 0.134; mean CPM = 13.06; mitogen-activated protein kinase-activated protein kinase 5" ID="ID_217833477" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1568780045" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K5: 1.21-fold Down; FDR = 0.6; PValue = 0.33; mean CPM = 8.023; mitogen-activated protein kinase kinase kinase 5" ID="ID_56453496" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDC42: 1.07-fold Down; FDR = 0.608; PValue = 0.335; mean CPM = 91.67; cell division cycle 42" ID="ID_798600152" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPKAPK2: 1.06-fold Down; FDR = 0.733; PValue = 0.435; mean CPM = 82.16; mitogen-activated protein kinase-activated protein kinase 2" ID="ID_1678391940" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLA2G4A: 1.08-fold Down; FDR = 0.836; PValue = 0.541; mean CPM = 40.53; phospholipase A2, group IVA (cytosolic, calcium-dependent)" ID="ID_409946442" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASGRF1: 1.14-fold Down; FDR = 0.903; PValue = 0.648; mean CPM = 1.594; Ras protein-specific guanine nucleotide-releasing factor 1" ID="ID_722677678" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB2: 1.05-fold Down; FDR = 0.903; PValue = 0.655; mean CPM = 110.8; transforming growth factor, beta 2" ID="ID_159516620" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_1497338540" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_1964393112" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_101893773" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DAXX: No Change; FDR = 1; PValue = 0.984; mean CPM = 106.5; Death domain-associated protein 6 (Daxx)(hDaxx)(Fas death domain-associated protein)(ETS1-associated protein 1)(EAP1)" ID="ID_417599382" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-23: FDR = 1.05e-09, PValue = 4.32e-10" ID="ID_1472182873" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_457145122" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1366430837" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5A: 2.28-fold Up; FDR = 6.87e-14; PValue = 8.58e-16; mean CPM = 21.55; signal transducer and activator of transcription 5A" ID="ID_399132411" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_1943291039" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1767715926" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1808932631" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1859313291" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_52399235" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_1469721965" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT4: 1.79-fold Up; FDR = 2.3e-05; PValue = 2.36e-06; mean CPM = 26.79; signal transducer and activator of transcription 4" ID="ID_986637113" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_1259640982" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS3: 1.69-fold Up; FDR = 0.000994; PValue = 0.000167; mean CPM = 37.76; suppressor of cytokine signaling 3" ID="ID_1848594185" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1459584415" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYK2: 1.24-fold Down; FDR = 0.0142; PValue = 0.00354; mean CPM = 42.58; tyrosine kinase 2" ID="ID_655458499" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBID: 1.47-fold Down; FDR = 0.0247; PValue = 0.0067; mean CPM = 6.446; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta" ID="ID_1024187007" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1395486916" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARAP3: 1.24-fold Down; FDR = 0.0271; PValue = 0.00747; mean CPM = 26.74; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3" ID="ID_157160251" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIE: 1.3-fold Down; FDR = 0.0272; PValue = 0.00752; mean CPM = 16.93; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon" ID="ID_583971493" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDPK1: 1.24-fold Down; FDR = 0.0361; PValue = 0.0105; mean CPM = 17.53; 3-phosphoinositide dependent protein kinase-1" ID="ID_1498186292" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1175300371" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIZ: 1.23-fold Up; FDR = 0.0949; PValue = 0.033; mean CPM = 91.08; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta" ID="ID_318909040" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_1982447594" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_647844228" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL23A: 1.39-fold Up; FDR = 0.348; PValue = 0.163; mean CPM = 4.542; interleukin 23, alpha subunit p19" ID="ID_556992241" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_322760986" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17A: 1.12-fold Up; FDR = 0.911; PValue = 0.706; mean CPM = 0.7895; interleukin 17A" ID="ID_1827955020" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17F: 1.11-fold Down; FDR = 0.948; PValue = 0.771; mean CPM = 1.150; interleukin 17F" ID="ID_229660189" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_1556138159" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL23R: 1.05-fold Down; FDR = 1; PValue = 0.994; mean CPM = 0.7958; interleukin 23 receptor" ID="ID_574019917" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="ICOS: FDR = 1.05e-09, PValue = 4.45e-10" ID="ID_933060047" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="HLA-DMB: 17.5-fold Up; FDR = 2.77e-15; PValue = 2.66e-17; mean CPM = 9.464; HLA class II histocompatibility antigen, DM beta chain Precursor (MHC class II antigen DMB)(Really interesting new gene 7 protein)" ID="ID_1828757577" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DPA1: 107-fold Up; FDR = 5.97e-15; PValue = 6.11e-17; mean CPM = 17.08; HLA class II histocompatibility antigen, DP alpha 1 chain Precursor (HLA-SB alpha chain)(MHC class II DP3-alpha)(DP(W3))(DP(W4))" ID="ID_1268393026" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DQB1: 31.1-fold Up; FDR = 6.93e-13; PValue = 1.1e-14; mean CPM = 6.675; Macaca mulatta MHC class II antigen (MAMU-DRB), mRNA." ID="ID_241073515" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA1: 15.1-fold Up; FDR = 1.9e-08; PValue = 8.86e-10; mean CPM = 3.665; HLA class II histocompatibility antigen, DQ alpha 1 chain precursor" ID="ID_1990956580" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-DPB1: 7.73-fold Up; FDR = 4.73e-08; PValue = 2.45e-09; mean CPM = 1.528; Macaca mulatta major histocompatibility complex, class II, DP beta (MAMU-DPB), mRNA." ID="ID_1005127262" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1106960714" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_1848694983" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_543910343" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC2: 4.03-fold Down; FDR = 0.000346; PValue = 5.06e-05; mean CPM = 1.347; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2" ID="ID_937000617" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAD: 1.36-fold Down; FDR = 0.000605; PValue = 9.52e-05; mean CPM = 48.46; BCL2-associated agonist of cell death" ID="ID_1708744117" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GAB2: 1.33-fold Down; FDR = 0.00208; PValue = 0.000387; mean CPM = 22.59; GRB2-associated binding protein 2" ID="ID_587353555" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG1: 1.31-fold Down; FDR = 0.00352; PValue = 0.000707; mean CPM = 53.66; phospholipase C, gamma 1" ID="ID_765987865" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1735192469" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GLRX3: 1.23-fold Up; FDR = 0.0155; PValue = 0.00392; mean CPM = 59.65; glutaredoxin 3" ID="ID_1232210746" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBID: 1.47-fold Down; FDR = 0.0247; PValue = 0.0067; mean CPM = 6.446; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta" ID="ID_926470425" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_120735025" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARAP3: 1.24-fold Down; FDR = 0.0271; PValue = 0.00747; mean CPM = 26.74; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3" ID="ID_1662808410" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIE: 1.3-fold Down; FDR = 0.0272; PValue = 0.00752; mean CPM = 16.93; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon" ID="ID_393541096" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDPK1: 1.24-fold Down; FDR = 0.0361; PValue = 0.0105; mean CPM = 17.53; 3-phosphoinositide dependent protein kinase-1" ID="ID_1468568453" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_883020478" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKAP: 1.19-fold Down; FDR = 0.0434; PValue = 0.013; mean CPM = 50.22; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein" ID="ID_818256225" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DAG1: 1.54-fold Down; FDR = 0.0661; PValue = 0.0214; mean CPM = 3.013; dystroglycan 1 (dystrophin-associated glycoprotein 1)" ID="ID_1467002276" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DOA: 2.74-fold Up; FDR = 0.0694; PValue = 0.0227; mean CPM = 0.9089; HLA class II histocompatibility antigen, DO alpha chain Precursor (MHC class II antigen DOA)(MHC DZ alpha)(MHC DN-alpha)" ID="ID_1730917124" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIZ: 1.23-fold Up; FDR = 0.0949; PValue = 0.033; mean CPM = 91.08; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta" ID="ID_30241183" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_438410433" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITPR3: 1.13-fold Up; FDR = 0.194; PValue = 0.079; mean CPM = 157.4; inositol 1,4,5-triphosphate receptor, type 3" ID="ID_1771440602" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_285845704" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAT: 1.44-fold Down; FDR = 0.234; PValue = 0.0996; mean CPM = 1.871; linker for activation of T cells" ID="ID_1091730524" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_1615919005" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_1149322960" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014796: 1.77-fold Up; FDR = 0.381; PValue = 0.182; mean CPM = 0.9085; Uncharacterized protein" ID="ID_1783132472" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_615982539" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LCP2: 1.4-fold Up; FDR = 0.496; PValue = 0.256; mean CPM = 1.322; Uncharacterized protein" ID="ID_347336731" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_1502504472" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDC42: 1.07-fold Down; FDR = 0.608; PValue = 0.335; mean CPM = 91.67; cell division cycle 42" ID="ID_1039665272" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD247: 1.43-fold Down; FDR = 0.695; PValue = 0.404; mean CPM = 0.9076; Macaca mulatta CD247 molecule (CD247), mRNA." ID="ID_67795925" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV1: 1.25-fold Down; FDR = 0.858; PValue = 0.572; mean CPM = 0.9515; vav 1 guanine nucleotide exchange factor" ID="ID_282988285" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZAP70: 1.25-fold Down; FDR = 0.872; PValue = 0.59; mean CPM = 0.8996; zeta-chain (TCR) associated protein kinase 70kDa" ID="ID_534111263" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DRB: 1.28-fold Up; FDR = 0.898; PValue = 0.624; mean CPM = 0.8112; MHC class II antigen; Uncharacterized protein" ID="ID_1147463056" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3D: 1.22-fold Down; FDR = 0.903; PValue = 0.641; mean CPM = 0.7953; CD3d molecule, delta (CD3-TCR complex)" ID="ID_402278365" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLA-DQA2: 1.13-fold Up; FDR = 0.908; PValue = 0.681; mean CPM = 0.7877; HLA class II histocompatibility antigen, DQ alpha 2 chain Precursor (HLA class II histocompatibility antigen, DQ(6) alpha chain)(DX alpha chain)(HLA-DQA1)" ID="ID_695071971" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICOSLG: 1.07-fold Down; FDR = 0.909; PValue = 0.684; mean CPM = 6.739; inducible T-cell co-stimulator ligand" ID="ID_478068283" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAT1: 1.13-fold Down; FDR = 0.911; PValue = 0.702; mean CPM = 0.7899; T cell receptor associated transmembrane adaptor 1" ID="ID_410871314" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKE: 1.03-fold Up; FDR = 0.929; PValue = 0.737; mean CPM = 21.61; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon" ID="ID_425143049" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICOS: 1.19-fold Up; FDR = 0.931; PValue = 0.741; mean CPM = 0.8158; Uncharacterized protein" ID="ID_1860016578" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMEM55B: 1.02-fold Up; FDR = 0.963; PValue = 0.798; mean CPM = 15.78; transmembrane protein 55B" ID="ID_185302350" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_659484661" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD80: 1.08-fold Up; FDR = 0.971; PValue = 0.812; mean CPM = 1.157; CD80 molecule" ID="ID_162405113" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITK: 1.07-fold Up; FDR = 1; PValue = 0.871; mean CPM = 0.9033; IL2-inducible T-cell kinase" ID="ID_1693581933" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_917697987" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3G: 1.03-fold Up; FDR = 1; PValue = 0.977; mean CPM = 0.8190; CD3g molecule, gamma (CD3-TCR complex)" ID="ID_615391081" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3E: 1.07-fold Down; FDR = 1; PValue = 0.981; mean CPM = 0.7994; Uncharacterized protein" ID="ID_1182518011" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD86: 1.01-fold Down; FDR = 1; PValue = 0.99; mean CPM = 0.8012; CD86 molecule" ID="ID_1743682658" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="General Jak/STAT: FDR = 1.07e-09, PValue = 4.74e-10" ID="ID_704811031" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="IRF9: 3.85-fold Up; FDR = 2.6e-19; PValue = 1.12e-21; mean CPM = 106.4; interferon regulatory factor 9" ID="ID_1023461658" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT2: 2.67-fold Up; FDR = 8.02e-19; PValue = 4.03e-21; mean CPM = 185.6; signal transducer and activator of transcription 2, 113kDa" ID="ID_556806667" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_1983673848" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_840397083" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL15: 17.3-fold Up; FDR = 2.78e-17; PValue = 1.92e-19; mean CPM = 5.103; Macaca mulatta interleukin 15 (IL15), mRNA." ID="ID_306723424" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL15RA: 19.4-fold Up; FDR = 4.04e-17; PValue = 2.89e-19; mean CPM = 5.291; interleukin 15 receptor, alpha" ID="ID_1401425844" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5A: 2.28-fold Up; FDR = 6.87e-14; PValue = 8.58e-16; mean CPM = 21.55; signal transducer and activator of transcription 5A" ID="ID_1658911454" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPRY1: 3.01-fold Up; FDR = 7.75e-14; PValue = 9.87e-16; mean CPM = 27.88; sprouty homolog 1, antagonist of FGF signaling (Drosophila)" ID="ID_334644672" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL7: 9.03-fold Up; FDR = 1.39e-13; PValue = 1.9e-15; mean CPM = 5.288; interleukin 7" ID="ID_1338780823" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_646023097" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND3: 2.27-fold Down; FDR = 8.38e-11; PValue = 2.15e-12; mean CPM = 86.90; cyclin D3" ID="ID_294217656" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIAS3: 1.63-fold Down; FDR = 2.24e-10; PValue = 6.51e-12; mean CPM = 53.00; protein inhibitor of activated STAT, 3" ID="ID_656990744" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPRY4: 2.68-fold Down; FDR = 2.32e-10; PValue = 6.78e-12; mean CPM = 12.79; sprouty homolog 4 (Drosophila)" ID="ID_1311153425" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL13RA1: 1.73-fold Up; FDR = 1.81e-09; PValue = 6.5e-11; mean CPM = 42.50; interleukin 13 receptor, alpha 1" ID="ID_1028822585" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CNTF: 4.71-fold Down; FDR = 3.15e-09; PValue = 1.21e-10; mean CPM = 2.528; ciliary neurotrophic factor" ID="ID_1790951722" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_1007113190" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL6ST: 1.78-fold Up; FDR = 1.86e-08; PValue = 8.65e-10; mean CPM = 437.6; interleukin 6 signal transducer (gp130, oncostatin M receptor)" ID="ID_1018125494" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL11RA: 1.66-fold Down; FDR = 1.74e-07; PValue = 1.02e-08; mean CPM = 33.61; interleukin 11 receptor, alpha" ID="ID_1313997035" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_437520052" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L1: 1.51-fold Up; FDR = 9.13e-07; PValue = 6.52e-08; mean CPM = 66.15; Bcl-2-like protein 1; Bcl-2-like protein 1 isoform 1; Uncharacterized protein" ID="ID_934712347" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_490407193" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_1349385004" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR2: 1.74-fold Up; FDR = 1.85e-06; PValue = 1.44e-07; mean CPM = 26.05; interferon (alpha, beta and omega) receptor 2" ID="ID_486058069" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_1418727944" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="OSMR: 1.49-fold Up; FDR = 1.63e-05; PValue = 1.62e-06; mean CPM = 180.8; Uncharacterized protein" ID="ID_666969663" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT4: 1.79-fold Up; FDR = 2.3e-05; PValue = 2.36e-06; mean CPM = 26.79; signal transducer and activator of transcription 4" ID="ID_356970141" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS5: 1.38-fold Up; FDR = 4.45e-05; PValue = 4.96e-06; mean CPM = 88.27; suppressor of cytokine signaling 5" ID="ID_1040015989" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL20RB: 3.26-fold Up; FDR = 6.13e-05; PValue = 7.16e-06; mean CPM = 4.526; interleukin 20 receptor beta" ID="ID_1064435666" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL6R: 3.84-fold Down; FDR = 6.68e-05; PValue = 7.89e-06; mean CPM = 4.840; interleukin 6 receptor" ID="ID_535303093" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LIFR: 1.59-fold Up; FDR = 0.000539; PValue = 8.35e-05; mean CPM = 35.74; leukemia inhibitory factor receptor alpha" ID="ID_1629719152" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS3: 1.69-fold Up; FDR = 0.000994; PValue = 0.000167; mean CPM = 37.76; suppressor of cytokine signaling 3" ID="ID_1633848785" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CISH: 1.95-fold Up; FDR = 0.00116; PValue = 0.0002; mean CPM = 5.083; cytokine inducible SH2-containing protein" ID="ID_484881243" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR1: 1.31-fold Up; FDR = 0.00151; PValue = 0.000268; mean CPM = 37.77; interferon gamma receptor 1" ID="ID_1038699496" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAM2: 1.3-fold Up; FDR = 0.00163; PValue = 0.000295; mean CPM = 50.32; signal transducing adaptor molecule (SH3 domain and ITAM motif) 2" ID="ID_746202713" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK3: 2.31-fold Up; FDR = 0.00186; PValue = 0.000342; mean CPM = 2.154; Janus kinase 3" ID="ID_1867108227" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTF1: 1.87-fold Up; FDR = 0.0019; PValue = 0.000351; mean CPM = 3.623; cardiotrophin 1" ID="ID_1428777787" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="OSM: 4.6-fold Down; FDR = 0.00251; PValue = 0.00048; mean CPM = 0.9104; oncostatin M" ID="ID_1465907873" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIAS1: 1.3-fold Up; FDR = 0.00259; PValue = 0.000498; mean CPM = 29.99; protein inhibitor of activated STAT, 1" ID="ID_1184527240" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CBLC: 2.87-fold Down; FDR = 0.00443; PValue = 0.000923; mean CPM = 3.105; Cas-Br-M (murine) ecotropic retroviral transforming sequence c" ID="ID_727890014" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12A: 2.09-fold Up; FDR = 0.00924; PValue = 0.00215; mean CPM = 2.872; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)" ID="ID_543911600" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLCF1: 1.4-fold Down; FDR = 0.00977; PValue = 0.00229; mean CPM = 21.80; cardiotrophin-like cytokine factor 1" ID="ID_1815708633" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR1: 1.27-fold Up; FDR = 0.0101; PValue = 0.00237; mean CPM = 82.39; Uncharacterized protein" ID="ID_175033450" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EPOR: 1.56-fold Down; FDR = 0.014; PValue = 0.00347; mean CPM = 3.898; erythropoietin receptor" ID="ID_1406387764" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYK2: 1.24-fold Down; FDR = 0.0142; PValue = 0.00354; mean CPM = 42.58; tyrosine kinase 2" ID="ID_1334171517" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSF2: 2.96-fold Down; FDR = 0.0174; PValue = 0.00447; mean CPM = 73.98; colony stimulating factor 2 (granulocyte-macrophage)" ID="ID_903373469" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS2: 1.31-fold Down; FDR = 0.0188; PValue = 0.0049; mean CPM = 35.29; suppressor of cytokine signaling 2" ID="ID_418129635" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRLF2: 2.92-fold Down; FDR = 0.0202; PValue = 0.00531; mean CPM = 1.758; cytokine receptor-like factor 2" ID="ID_805085825" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL20RA: 2.25-fold Up; FDR = 0.0255; PValue = 0.00695; mean CPM = 1.386; interleukin 20 receptor, alpha" ID="ID_1092235192" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1978848266" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR2: 1.23-fold Up; FDR = 0.0258; PValue = 0.00707; mean CPM = 46.52; interferon gamma receptor 2 (interferon gamma transducer 1)" ID="ID_1566355499" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIM1: 1.39-fold Down; FDR = 0.0325; PValue = 0.00926; mean CPM = 21.11; pim-1 oncogene" ID="ID_624450120" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LEP: 1.67-fold Down; FDR = 0.0401; PValue = 0.0118; mean CPM = 63.70; leptin" ID="ID_1208148525" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TPO: 2.96-fold Down; FDR = 0.0533; PValue = 0.0166; mean CPM = 1.110; thyroid peroxidase" ID="ID_657059960" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIAS4: 1.22-fold Down; FDR = 0.0547; PValue = 0.0171; mean CPM = 18.45; protein inhibitor of activated STAT, 4" ID="ID_631376962" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_1620181244" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL7R: 1.76-fold Down; FDR = 0.0698; PValue = 0.0229; mean CPM = 3.067; interleukin 7 receptor" ID="ID_1253705586" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSF3: 2.55-fold Up; FDR = 0.0701; PValue = 0.023; mean CPM = 72.12; colony stimulating factor 3 (granulocyte)" ID="ID_1765668020" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT6: 1.18-fold Up; FDR = 0.0727; PValue = 0.024; mean CPM = 217.5; signal transducer and activator of transcription 6, interleukin-4 induced" ID="ID_1931596561" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL13RA2: 2.13-fold Up; FDR = 0.0909; PValue = 0.0313; mean CPM = 1.485; Interleukin-13 receptor subunit alpha-2; Uncharacterized protein" ID="ID_601051284" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_1660664201" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS2: 1.17-fold Up; FDR = 0.1; PValue = 0.0353; mean CPM = 31.79; son of sevenless homolog 2 (Drosophila)" ID="ID_1561238885" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL28RA: 2.43-fold Down; FDR = 0.115; PValue = 0.0414; mean CPM = 0.9001; interleukin 28 receptor, alpha (interferon, lambda receptor)" ID="ID_861832479" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND1: 1.17-fold Up; FDR = 0.121; PValue = 0.0443; mean CPM = 867.3; cyclin D1" ID="ID_838596801" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPRED1: 1.15-fold Up; FDR = 0.143; PValue = 0.0543; mean CPM = 41.74; sprouty-related, EVH1 domain containing 1" ID="ID_466729003" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPRY3: 1.5-fold Up; FDR = 0.161; PValue = 0.0627; mean CPM = 2.641; sprouty homolog 3 (Drosophila)" ID="ID_627218063" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1256772076" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_606695228" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12RB2: 1.42-fold Down; FDR = 0.299; PValue = 0.135; mean CPM = 1.728; interleukin 12 receptor, beta 2" ID="ID_84461495" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EP300: 1.11-fold Up; FDR = 0.312; PValue = 0.142; mean CPM = 162.8; E1A binding protein p300" ID="ID_249504054" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_1173924334" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND2: 1.2-fold Up; FDR = 0.335; PValue = 0.155; mean CPM = 76.91; cyclin D2" ID="ID_577557687" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL23A: 1.39-fold Up; FDR = 0.348; PValue = 0.163; mean CPM = 4.542; interleukin 23, alpha subunit p19" ID="ID_1674129690" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GHR: 1.23-fold Up; FDR = 0.369; PValue = 0.175; mean CPM = 6.312; growth hormone receptor" ID="ID_758855205" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_716477943" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EPO: 1.77-fold Up; FDR = 0.39; PValue = 0.188; mean CPM = 0.9174; Macaca mulatta erythropoietin (EPO), mRNA." ID="ID_1638893067" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MPL: 1.3-fold Down; FDR = 0.411; PValue = 0.201; mean CPM = 2.108; myeloproliferative leukemia virus oncogene" ID="ID_1899717793" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CNTFR: 1.67-fold Down; FDR = 0.435; PValue = 0.216; mean CPM = 1.033; Uncharacterized protein" ID="ID_987393885" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_180894329" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL19: 1.65-fold Down; FDR = 0.455; PValue = 0.228; mean CPM = 0.9514; interleukin 19" ID="ID_606963636" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LEPR: 1.52-fold Down; FDR = 0.489; PValue = 0.251; mean CPM = 1.051; leptin receptor" ID="ID_261118163" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPRY2: 1.09-fold Down; FDR = 0.515; PValue = 0.269; mean CPM = 27.90; sprouty homolog 2 (Drosophila)" ID="ID_622112512" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL10RA: 1.55-fold Down; FDR = 0.516; PValue = 0.269; mean CPM = 0.9545; interleukin 10 receptor, alpha" ID="ID_92446287" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_1551988799" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL21R: 1.56-fold Down; FDR = 0.534; PValue = 0.282; mean CPM = 1.021; interleukin 21 receptor" ID="ID_83295103" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL24: 1.37-fold Down; FDR = 0.563; PValue = 0.303; mean CPM = 26.16; interleukin 24" ID="ID_210121621" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL9R: 2.21-fold Down; FDR = 0.63; PValue = 0.352; mean CPM = 0.8661; interleukin 9 receptor" ID="ID_1892818317" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNE: 1.18-fold Up; FDR = 0.646; PValue = 0.364; mean CPM = 2.614; interferon, epsilon" ID="ID_530055883" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LIF: 1.07-fold Down; FDR = 0.702; PValue = 0.409; mean CPM = 148.6; leukemia inhibitory factor (cholinergic differentiation factor)" ID="ID_127835514" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12RB1: 1.39-fold Up; FDR = 0.703; PValue = 0.41; mean CPM = 0.9665; interleukin 12 receptor, beta 1" ID="ID_304886489" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL11: 1.13-fold Up; FDR = 0.715; PValue = 0.42; mean CPM = 128.8; interleukin 11" ID="ID_1882719197" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNB1: 1.79-fold Up; FDR = 0.731; PValue = 0.433; mean CPM = 0.8526; interferon, beta 1, fibroblast" ID="ID_1550274489" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL4R: 1.05-fold Down; FDR = 0.803; PValue = 0.499; mean CPM = 193.5; interleukin 4 receptor" ID="ID_247637767" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIAS2: 1.06-fold Down; FDR = 0.807; PValue = 0.503; mean CPM = 19.53; protein inhibitor of activated STAT, 2" ID="ID_600355704" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA6: 1.41-fold Down; FDR = 0.807; PValue = 0.504; mean CPM = 0.8019; interferon, alpha 6" ID="ID_878795952" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CBL: 1.05-fold Down; FDR = 0.824; PValue = 0.524; mean CPM = 51.06; Cas-Br-M (murine) ecotropic retroviral transforming sequence" ID="ID_86283760" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL28B: 1.53-fold Down; FDR = 0.836; PValue = 0.541; mean CPM = 0.8237; interleukin 28B (interferon, lambda 3)" ID="ID_456781906" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL22RA1: 1.26-fold Up; FDR = 0.846; PValue = 0.555; mean CPM = 0.9674; interleukin 22 receptor, alpha 1" ID="ID_1881625744" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS7: 1.07-fold Down; FDR = 0.847; PValue = 0.556; mean CPM = 7.514; suppressor of cytokine signaling 7" ID="ID_192231114" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CBLB: 1.04-fold Down; FDR = 0.859; PValue = 0.574; mean CPM = 64.59; Cas-Br-M (murine) ecotropic retroviral transforming sequence b" ID="ID_1596710935" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL29: 1.38-fold Down; FDR = 0.898; PValue = 0.624; mean CPM = 0.8355; interleukin 29 (interferon, lambda 1)" ID="ID_146565091" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAM: 1.04-fold Down; FDR = 0.899; PValue = 0.627; mean CPM = 29.84; signal transducing adaptor molecule (SH3 domain and ITAM motif) 1" ID="ID_432741778" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL22RA2: 1.2-fold Down; FDR = 0.899; PValue = 0.629; mean CPM = 0.7954; interleukin 22 receptor, alpha 2" ID="ID_1799712415" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_692949600" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSF2RA: 1.19-fold Up; FDR = 0.906; PValue = 0.666; mean CPM = 0.9897; colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)" ID="ID_1695660031" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA13: 1.13-fold Up; FDR = 0.908; PValue = 0.677; mean CPM = 0.7960; interferon, alpha 13" ID="ID_994994407" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA8: 1.13-fold Down; FDR = 0.911; PValue = 0.702; mean CPM = 0.7910; interferon, alpha 8" ID="ID_205865964" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL9: 1.14-fold Up; FDR = 0.911; PValue = 0.705; mean CPM = 0.7910; interleukin 9" ID="ID_212560235" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSF3R: 1.13-fold Down; FDR = 0.921; PValue = 0.723; mean CPM = 0.9331; colony stimulating factor 3 receptor (granulocyte)" ID="ID_90393323" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS4: 1.03-fold Up; FDR = 0.921; PValue = 0.724; mean CPM = 17.28; suppressor of cytokine signaling 4" ID="ID_1619568529" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL22: 1.33-fold Down; FDR = 0.928; PValue = 0.735; mean CPM = 0.8193; interleukin 22" ID="ID_959250207" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL4: 1.27-fold Down; FDR = 0.933; PValue = 0.745; mean CPM = 0.8077; interleukin 4" ID="ID_1185385130" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2RA: 1.08-fold Up; FDR = 0.945; PValue = 0.766; mean CPM = 0.8493; interleukin 2 receptor, alpha" ID="ID_931062984" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL21: 1.04-fold Up; FDR = 0.948; PValue = 0.773; mean CPM = 0.8164; interleukin 21" ID="ID_640312370" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL20: 1.22-fold Up; FDR = 0.951; PValue = 0.779; mean CPM = 0.8273; interleukin 20" ID="ID_1886721281" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL5RA: 1.1-fold Up; FDR = 0.958; PValue = 0.791; mean CPM = 0.8108; interleukin 5 receptor, alpha" ID="ID_1604053475" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA14: 1.22-fold Up; FDR = 0.965; PValue = 0.802; mean CPM = 0.8654; interferon, alpha 14" ID="ID_1597768993" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL13: 1.05-fold Up; FDR = 0.967; PValue = 0.805; mean CPM = 0.8212; interleukin 13" ID="ID_90384383" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA4: 1.28-fold Down; FDR = 0.983; PValue = 0.829; mean CPM = 0.8584; interferon, alpha 4" ID="ID_281152960" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12B: 1.07-fold Up; FDR = 0.983; PValue = 0.831; mean CPM = 0.8197; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)" ID="ID_798401656" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREBBP: 1.01-fold Down; FDR = 0.993; PValue = 0.847; mean CPM = 137.7; CREB binding protein" ID="ID_293867017" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL5: 1.05-fold Down; FDR = 1; PValue = 0.862; mean CPM = 1.367; interleukin 5 (colony-stimulating factor, eosinophil)" ID="ID_1098087636" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRLR: 1.06-fold Down; FDR = 1; PValue = 0.889; mean CPM = 1.017; prolactin receptor" ID="ID_847483544" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL3: 1.17-fold Down; FDR = 1; PValue = 0.9; mean CPM = 0.8325; Macaca mulatta interleukin 3 (colony-stimulating factor, multiple) (IL3), mRNA." ID="ID_1913753281" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL10: 1.21-fold Down; FDR = 1; PValue = 0.964; mean CPM = 0.8614; interleukin 10" ID="ID_886538960" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL23R: 1.05-fold Down; FDR = 1; PValue = 0.994; mean CPM = 0.7958; interleukin 23 receptor" ID="ID_373014114" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2: 1.03-fold Up; FDR = 1; PValue = 0.998; mean CPM = 0.7974; interleukin 2" ID="ID_13528094" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA1: No Change; FDR = 1; PValue = 0.998; mean CPM = 0.8014; interferon, alpha 1" ID="ID_225572245" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL26: No Change; FDR = 1; PValue = 1; mean CPM = 0.7833; interleukin 26" ID="ID_1516648545" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNK: No Change; FDR = 1; PValue = 1; mean CPM = 0.7868; interferon, kappa" ID="ID_32607363" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNW1: No Change; FDR = 1; PValue = 1; mean CPM = 0.7851; interferon, omega 1" ID="ID_535550761" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-5 : FDR = 4.49e-09, PValue = 2.08e-09" ID="ID_1806415336" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_1209266491" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1135661230" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5A: 2.28-fold Up; FDR = 6.87e-14; PValue = 8.58e-16; mean CPM = 21.55; signal transducer and activator of transcription 5A" ID="ID_1024808541" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_1085467790" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_1570799370" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_28993670" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_1268359198" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_222438369" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL11: 6.86-fold Up; FDR = 2.69e-05; PValue = 2.82e-06; mean CPM = 4.204; chemokine (C-C motif) ligand 11" ID="ID_1140959117" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB2: 1.38-fold Down; FDR = 4.66e-05; PValue = 5.24e-06; mean CPM = 61.90; ribosomal protein S6 kinase, 70kDa, polypeptide 2" ID="ID_1117682284" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTOR: 1.3-fold Down; FDR = 0.00117; PValue = 0.000201; mean CPM = 107.5; mechanistic target of rapamycin (serine/threonine kinase)" ID="ID_1818945265" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1408404759" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA1: 1.25-fold Down; FDR = 0.0241; PValue = 0.00652; mean CPM = 21.28; ribosomal protein S6 kinase, 90kDa, polypeptide 1" ID="ID_592118261" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1316548649" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_1630219082" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIM1: 1.39-fold Down; FDR = 0.0325; PValue = 0.00926; mean CPM = 21.11; pim-1 oncogene" ID="ID_991584699" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_1169248919" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_1797433156" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_1878871952" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3A: 1.18-fold Down; FDR = 0.097; PValue = 0.0338; mean CPM = 25.14; Glycogen synthase kinase-3 alpha; Uncharacterized protein" ID="ID_1372389044" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_470568445" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPRED1: 1.15-fold Up; FDR = 0.143; PValue = 0.0543; mean CPM = 41.74; sprouty-related, EVH1 domain containing 1" ID="ID_1139768409" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1701221558" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1325767290" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_529126553" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_52896808" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2: 1.48-fold Up; FDR = 0.384; PValue = 0.184; mean CPM = 1.344; Uncharacterized protein" ID="ID_1344750779" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_569420395" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_754251289" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOXO3: 1.08-fold Down; FDR = 0.55; PValue = 0.294; mean CPM = 48.45; forkhead box O3" ID="ID_668287367" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6: 1.08-fold Up; FDR = 0.584; PValue = 0.318; mean CPM = 892.5; ribosomal protein S6" ID="ID_507265869" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_81789899" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD4: 1.27-fold Up; FDR = 0.807; PValue = 0.503; mean CPM = 1.122; CD4 molecule" ID="ID_515938258" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1216202377" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB1: 1.04-fold Up; FDR = 0.88; PValue = 0.6; mean CPM = 30.80; Uncharacterized protein" ID="ID_951439963" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DRB: 1.28-fold Up; FDR = 0.898; PValue = 0.624; mean CPM = 0.8112; MHC class II antigen; Uncharacterized protein" ID="ID_353947737" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR3: 1.43-fold Up; FDR = 0.906; PValue = 0.665; mean CPM = 0.8397; chemokine (C-C motif) receptor 3" ID="ID_1571859579" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL4: 1.27-fold Down; FDR = 0.933; PValue = 0.745; mean CPM = 0.8077; interleukin 4" ID="ID_236034525" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_553262740" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL5RA: 1.1-fold Up; FDR = 0.958; PValue = 0.791; mean CPM = 0.8108; interleukin 5 receptor, alpha" ID="ID_1260202545" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL5: 1.05-fold Down; FDR = 1; PValue = 0.862; mean CPM = 1.367; interleukin 5 (colony-stimulating factor, eosinophil)" ID="ID_1127688209" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BTK: No Change; FDR = 1; PValue = 0.965; mean CPM = 0.8336; Bruton agammaglobulinemia tyrosine kinase" ID="ID_1521184015" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SYK: 1.11-fold Up; FDR = 1; PValue = 0.977; mean CPM = 0.8420; spleen tyrosine kinase" ID="ID_638598528" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="CD40: FDR = 1.02e-08, PValue = 4.93e-09" ID="ID_320282526" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="ICAM1: 24.6-fold Up; FDR = 2.39e-17; PValue = 1.64e-19; mean CPM = 232.4; intercellular adhesion molecule 1" ID="ID_1220684649" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TANK: 1.77-fold Up; FDR = 3.82e-13; PValue = 5.66e-15; mean CPM = 62.24; TRAF family member-associated NFKB activator" ID="ID_1887162710" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_515712054" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_874725784" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1387452492" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8IP1: 1.53-fold Down; FDR = 4.63e-07; PValue = 3.04e-08; mean CPM = 28.91; mitogen-activated protein kinase 8 interacting protein 1" ID="ID_819373734" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_973420784" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_393780187" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF1: 1.51-fold Up; FDR = 5.28e-06; PValue = 4.58e-07; mean CPM = 22.13; activating transcription factor 1" ID="ID_1417097520" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K3: 1.45-fold Down; FDR = 7.01e-06; PValue = 6.34e-07; mean CPM = 180.1; mitogen-activated protein kinase kinase 3" ID="ID_656661257" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8IP3: 1.77-fold Down; FDR = 1.28e-05; PValue = 1.24e-06; mean CPM = 65.23; mitogen-activated protein kinase 8 interacting protein 3" ID="ID_1576524746" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1499531291" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF1: 2.6-fold Down; FDR = 1.48e-05; PValue = 1.46e-06; mean CPM = 20.19; TNF receptor-associated factor 1" ID="ID_857502083" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFAIP3: 1.79-fold Up; FDR = 3.14e-05; PValue = 3.34e-06; mean CPM = 52.47; tumor necrosis factor, alpha-induced protein 3" ID="ID_213483049" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_1894285594" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40: 2.76-fold Up; FDR = 0.00039; PValue = 5.79e-05; mean CPM = 9.139; CD40 molecule, TNF receptor superfamily member 5" ID="ID_456016469" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_847405207" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DUSP1: 1.39-fold Down; FDR = 0.00173; PValue = 0.000315; mean CPM = 355.2; dual specificity phosphatase 1" ID="ID_1072450282" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK3: 2.31-fold Up; FDR = 0.00186; PValue = 0.000342; mean CPM = 2.154; Janus kinase 3" ID="ID_1148770150" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_52604993" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K14: 1.47-fold Down; FDR = 0.00704; PValue = 0.00157; mean CPM = 9.470; mitogen-activated protein kinase kinase kinase 14" ID="ID_1203808554" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K3: 1.26-fold Down; FDR = 0.00786; PValue = 0.00178; mean CPM = 38.85; mitogen-activated protein kinase kinase kinase 3" ID="ID_1158932788" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_844436230" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1652682212" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKAP: 1.19-fold Down; FDR = 0.0434; PValue = 0.013; mean CPM = 50.22; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein" ID="ID_1595269008" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_1737640398" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_1743540545" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1229488255" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1307162415" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8IP2: 1.29-fold Down; FDR = 0.543; PValue = 0.289; mean CPM = 2.167; mitogen-activated protein kinase 8 interacting protein 2" ID="ID_777835127" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF3: 1.07-fold Up; FDR = 0.611; PValue = 0.338; mean CPM = 34.56; TNF receptor-associated factor 3" ID="ID_1780649901" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPKAPK2: 1.06-fold Down; FDR = 0.733; PValue = 0.435; mean CPM = 82.16; mitogen-activated protein kinase-activated protein kinase 2" ID="ID_1644831078" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1178274630" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FCER2: 1.41-fold Up; FDR = 0.864; PValue = 0.58; mean CPM = 0.8258; Fc fragment of IgE, low affinity II, receptor for (CD23)" ID="ID_780612556" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1658614687" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K2: 1.03-fold Up; FDR = 0.924; PValue = 0.73; mean CPM = 40.64; mitogen-activated protein kinase kinase kinase 2" ID="ID_182094544" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_927931635" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_217120593" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF3IP2: 1.01-fold Down; FDR = 1; PValue = 0.913; mean CPM = 29.19; TRAF3 interacting protein 2" ID="ID_1421567456" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40LG: 1.01-fold Down; FDR = 1; PValue = 0.982; mean CPM = 0.8653; CD40 ligand" ID="ID_1679974933" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="CTL mediated immune response: FDR = 1.32e-08, PValue = 6.62e-09" ID="ID_690910123" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="ICAM1: 24.6-fold Up; FDR = 2.39e-17; PValue = 1.64e-19; mean CPM = 232.4; intercellular adhesion molecule 1" ID="ID_1792987555" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB2: 1.55-fold Down; FDR = 0.0187; PValue = 0.00485; mean CPM = 34.87; Integrin beta" ID="ID_1167571201" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD247: 1.43-fold Down; FDR = 0.695; PValue = 0.404; mean CPM = 0.9076; Macaca mulatta CD247 molecule (CD247), mRNA." ID="ID_997913661" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GZMB: 1.43-fold Up; FDR = 0.83; PValue = 0.532; mean CPM = 0.7972; granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)" ID="ID_933861647" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRF1: 1.75-fold Up; FDR = 0.841; PValue = 0.548; mean CPM = 0.8583; perforin 1 (pore forming protein)" ID="ID_1647620451" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3D: 1.22-fold Down; FDR = 0.903; PValue = 0.641; mean CPM = 0.7953; CD3d molecule, delta (CD3-TCR complex)" ID="ID_334700001" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FASLG: 1.2-fold Down; FDR = 0.941; PValue = 0.757; mean CPM = 0.8088; Fas ligand (TNF superfamily, member 6)" ID="ID_1641761087" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAL: 1.03-fold Up; FDR = 1; PValue = 0.95; mean CPM = 1.035; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)" ID="ID_258505249" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3G: 1.03-fold Up; FDR = 1; PValue = 0.977; mean CPM = 0.8190; CD3g molecule, gamma (CD3-TCR complex)" ID="ID_1149591411" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD3E: 1.07-fold Down; FDR = 1; PValue = 0.981; mean CPM = 0.7994; Uncharacterized protein" ID="ID_1934343199" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="PI3K: FDR = 1.56e-08, PValue = 8.07e-09" ID="ID_880222378" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="FGF1: 5.05-fold Down; FDR = 8.21e-14; PValue = 1.05e-15; mean CPM = 19.54; fibroblast growth factor 1 (acidic)" ID="ID_375850260" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRS1: 2.78-fold Up; FDR = 7.67e-09; PValue = 3.19e-10; mean CPM = 26.55; Uncharacterized protein" ID="ID_1445490818" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF2: 2.42-fold Up; FDR = 9.98e-09; PValue = 4.31e-10; mean CPM = 134.8; fibroblast growth factor 2 (basic)" ID="ID_1957512749" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGFR2: 3.45-fold Down; FDR = 1.04e-08; PValue = 4.53e-10; mean CPM = 5.064; fibroblast growth factor receptor 2" ID="ID_1341554266" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INSR: 1.93-fold Down; FDR = 1.24e-08; PValue = 5.48e-10; mean CPM = 118.3; insulin receptor" ID="ID_1610141429" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_316085421" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_585685766" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGFR3: 3.85-fold Down; FDR = 2.66e-06; PValue = 2.13e-07; mean CPM = 2.800; fibroblast growth factor receptor 3" ID="ID_1240120306" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FRS2: 1.17-fold Up; FDR = 0.105; PValue = 0.0373; mean CPM = 37.92; fibroblast growth factor receptor substrate 2" ID="ID_347482144" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGFR1: 1.15-fold Down; FDR = 0.139; PValue = 0.0525; mean CPM = 89.41; fibroblast growth factor receptor 1" ID="ID_557266918" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF23: 2.01-fold Down; FDR = 0.188; PValue = 0.0759; mean CPM = 0.9718; fibroblast growth factor 23" ID="ID_526177975" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_663175774" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF10: 1.55-fold Down; FDR = 0.257; PValue = 0.112; mean CPM = 3.488; fibroblast growth factor 10" ID="ID_8346727" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_821565897" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DOK1: 1.12-fold Down; FDR = 0.406; PValue = 0.198; mean CPM = 92.16; docking protein 1, 62kDa (downstream of tyrosine kinase 1)" ID="ID_765091569" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_1783110494" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF18: 1.55-fold Down; FDR = 0.548; PValue = 0.293; mean CPM = 0.9359; fibroblast growth factor 18" ID="ID_1156416175" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GAB1: 1.1-fold Up; FDR = 0.635; PValue = 0.356; mean CPM = 14.59; GRB2-associated binding protein 1" ID="ID_544728078" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF5: 1.1-fold Down; FDR = 0.646; PValue = 0.364; mean CPM = 54.02; fibroblast growth factor 5" ID="ID_319720443" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF9: 1.77-fold Up; FDR = 0.74; PValue = 0.441; mean CPM = 0.8485; fibroblast growth factor 9 (glia-activating factor)" ID="ID_431504235" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF8: 1.75-fold Down; FDR = 0.783; PValue = 0.48; mean CPM = 0.8245; Uncharacterized protein" ID="ID_671492278" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KL: 1.4-fold Up; FDR = 0.849; PValue = 0.559; mean CPM = 0.8285; klotho" ID="ID_745169107" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF3: 1.22-fold Down; FDR = 0.903; PValue = 0.641; mean CPM = 0.7938; fibroblast growth factor 3 (murine mammary tumor virus integration site (v-int-2) oncogene homolog)" ID="ID_1482929570" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF17: 1.34-fold Down; FDR = 0.903; PValue = 0.662; mean CPM = 0.8230; fibroblast growth factor 17" ID="ID_1488026972" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF19: 1.33-fold Down; FDR = 0.921; PValue = 0.724; mean CPM = 0.8101; fibroblast growth factor 19" ID="ID_300221199" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF6: 1.15-fold Up; FDR = 0.948; PValue = 0.773; mean CPM = 0.8082; fibroblast growth factor 6" ID="ID_1806402577" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR9: 1.01-fold Down; FDR = 1; PValue = 0.859; mean CPM = 21.45; Macaca mulatta toll-like receptor 9 (TLR9), mRNA." ID="ID_985294014" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R4: 1.01-fold Down; FDR = 1; PValue = 0.913; mean CPM = 41.33; phosphoinositide-3-kinase, regulatory subunit 4" ID="ID_450197036" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF20: No Change; FDR = 1; PValue = 1; mean CPM = 0.7796; fibroblast growth factor 20" ID="ID_1380344506" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="RANTES / CCL5: FDR = 1.59e-08, PValue = 8.56e-09" ID="ID_1188289073" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CCL2: 24.6-fold Up; FDR = 1.83e-15; PValue = 1.69e-17; mean CPM = 668.2; Macaca mulatta chemokine (C-C motif) ligand 2 (CCL2), mRNA." ID="ID_461406931" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNB4: 2.14-fold Up; FDR = 2.52e-09; PValue = 9.35e-11; mean CPM = 33.45; guanine nucleotide binding protein (G protein), beta polypeptide 4" ID="ID_1825909343" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2B: 3.54-fold Up; FDR = 1.24e-07; PValue = 7.07e-09; mean CPM = 5.971; PTK2B protein tyrosine kinase 2 beta" ID="ID_1563692471" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL5: 6.74-fold Up; FDR = 2.65e-07; PValue = 1.64e-08; mean CPM = 30.35; chemokine (C-C motif) ligand 5" ID="ID_1726779984" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNA1C: 2.79-fold Down; FDR = 3.33e-07; PValue = 2.1e-08; mean CPM = 34.91; Uncharacterized protein" ID="ID_877698343" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1220400668" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCE: 1.73-fold Up; FDR = 0.00013; PValue = 1.67e-05; mean CPM = 10.87; protein kinase C, epsilon" ID="ID_416752842" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNB3: 1.91-fold Down; FDR = 0.000162; PValue = 2.14e-05; mean CPM = 7.202; guanine nucleotide binding protein (G protein), beta polypeptide 3" ID="ID_80694728" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALM3: 1.41-fold Down; FDR = 0.000714; PValue = 0.000115; mean CPM = 94.24; calmodulin 3 (phosphorylase kinase, delta)" ID="ID_55181623" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNA12: 1.32-fold Down; FDR = 0.000955; PValue = 0.00016; mean CPM = 33.75; Uncharacterized protein" ID="ID_993247674" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCH: 1.98-fold Down; FDR = 0.00105; PValue = 0.000179; mean CPM = 3.182; protein kinase C, eta" ID="ID_1084647426" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAS1: 1.31-fold Down; FDR = 0.00158; PValue = 0.000283; mean CPM = 564.9; Uncharacterized protein" ID="ID_832004296" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKD3: 1.29-fold Up; FDR = 0.00214; PValue = 0.0004; mean CPM = 43.43; protein kinase D3" ID="ID_50311114" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCR4: 4.65-fold Down; FDR = 0.00226; PValue = 0.000426; mean CPM = 2.073; chemokine (C-X-C motif) receptor 4" ID="ID_1574857953" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG1: 1.31-fold Down; FDR = 0.00352; PValue = 0.000707; mean CPM = 53.66; phospholipase C, gamma 1" ID="ID_854913602" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNA2D4: 1.71-fold Up; FDR = 0.00375; PValue = 0.000764; mean CPM = 4.238; calcium channel, voltage-dependent, alpha 2/delta subunit 4" ID="ID_44483495" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_89836778" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCZ: 1.51-fold Up; FDR = 0.0152; PValue = 0.00381; mean CPM = 10.46; protein kinase C, zeta" ID="ID_1092409351" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_409514496" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNA1F: 2.4-fold Down; FDR = 0.0315; PValue = 0.00892; mean CPM = 1.129; calcium channel, voltage-dependent, L type, alpha 1F subunit" ID="ID_1185155591" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNA13: 1.25-fold Up; FDR = 0.0428; PValue = 0.0128; mean CPM = 15.41; guanine nucleotide binding protein (G protein), alpha 13" ID="ID_804159691" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNA1D: 2.26-fold Down; FDR = 0.0434; PValue = 0.013; mean CPM = 1.171; calcium channel, voltage-dependent, L type, alpha 1D subunit" ID="ID_1670295323" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL3: 2.04-fold Down; FDR = 0.067; PValue = 0.0218; mean CPM = 3.575; chemokine (C-C motif) ligand 3" ID="ID_1655237381" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNA2D3: 1.74-fold Down; FDR = 0.0883; PValue = 0.0302; mean CPM = 6.008; calcium channel, voltage-dependent, alpha 2/delta subunit 3" ID="ID_56285050" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALM1: 1.18-fold Down; FDR = 0.104; PValue = 0.0368; mean CPM = 292.9; calmodulin 1 (phosphorylase kinase, delta)" ID="ID_1051405508" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG2: 1.64-fold Up; FDR = 0.117; PValue = 0.0421; mean CPM = 2.320; guanine nucleotide binding protein (G protein), gamma 2" ID="ID_1014133754" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_1303426292" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1992539200" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG3: 1.6-fold Down; FDR = 0.155; PValue = 0.0601; mean CPM = 1.706; guanine nucleotide binding protein (G protein), gamma 3" ID="ID_1130739179" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNB1: 1.31-fold Down; FDR = 0.157; PValue = 0.0608; mean CPM = 5.053; calcium channel, voltage-dependent, beta 1 subunit" ID="ID_658415099" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALM1: 1.11-fold Up; FDR = 0.343; PValue = 0.16; mean CPM = 412.7; Calmodulin; Uncharacterized protein" ID="ID_852352047" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNA14: 1.45-fold Up; FDR = 0.381; PValue = 0.182; mean CPM = 1.368; guanine nucleotide binding protein (G protein), alpha 14" ID="ID_647749797" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1335399700" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKD1: 1.14-fold Down; FDR = 0.433; PValue = 0.215; mean CPM = 41.81; protein kinase D1" ID="ID_126411180" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNB3: 1.1-fold Down; FDR = 0.459; PValue = 0.231; mean CPM = 26.21; calcium channel, voltage-dependent, beta 3 subunit" ID="ID_1935035845" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNA11: 1.09-fold Down; FDR = 0.485; PValue = 0.248; mean CPM = 43.16; guanine nucleotide binding protein (G protein), alpha 11 (Gq class)" ID="ID_467135360" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR5: 1.56-fold Down; FDR = 0.487; PValue = 0.249; mean CPM = 1.064; chemokine (C-C motif) receptor 5" ID="ID_774273400" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL12: 1.27-fold Down; FDR = 0.488; PValue = 0.251; mean CPM = 4.383; chemokine (C-X-C motif) ligand 12" ID="ID_1400102613" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCI: 1.08-fold Up; FDR = 0.518; PValue = 0.271; mean CPM = 47.99; protein kinase C, iota" ID="ID_581398400" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCQ: 1.56-fold Up; FDR = 0.522; PValue = 0.274; mean CPM = 1.047; Uncharacterized protein" ID="ID_550180105" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG4: 1.65-fold Down; FDR = 0.524; PValue = 0.275; mean CPM = 0.8771; guanine nucleotide binding protein (G protein), gamma 4" ID="ID_1947801761" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAL: 1.29-fold Down; FDR = 0.53; PValue = 0.279; mean CPM = 1.742; guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type" ID="ID_505274049" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNA2D1: 1.13-fold Down; FDR = 0.562; PValue = 0.303; mean CPM = 10.13; calcium channel, voltage-dependent, alpha 2/delta subunit 1" ID="ID_622207246" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNB1: 1.08-fold Down; FDR = 0.565; PValue = 0.305; mean CPM = 299.4; guanine nucleotide binding protein (G protein), beta polypeptide 1" ID="ID_438338239" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNA1I: 1.48-fold Down; FDR = 0.57; PValue = 0.309; mean CPM = 0.9895; Uncharacterized protein" ID="ID_757302650" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNB2: 1.4-fold Down; FDR = 0.573; PValue = 0.31; mean CPM = 1.119; calcium channel, voltage-dependent, beta 2 subunit" ID="ID_403638495" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCG: 1.47-fold Down; FDR = 0.609; PValue = 0.336; mean CPM = 0.9297; protein kinase C, gamma" ID="ID_1126828573" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNB2: 1.06-fold Down; FDR = 0.685; PValue = 0.395; mean CPM = 129.1; guanine nucleotide binding protein (G protein), beta polypeptide 2" ID="ID_1981251674" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCD: 1.06-fold Up; FDR = 0.696; PValue = 0.404; mean CPM = 37.45; protein kinase C, delta" ID="ID_1005854502" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCB: 1.86-fold Up; FDR = 0.727; PValue = 0.43; mean CPM = 0.8705; protein kinase C, beta" ID="ID_1077762171" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNA1H: 1.38-fold Down; FDR = 0.735; PValue = 0.437; mean CPM = 0.9035; calcium channel, voltage-dependent, T type, alpha 1H subunit" ID="ID_691227606" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNG1: 1.82-fold Up; FDR = 0.74; PValue = 0.442; mean CPM = 0.8669; calcium channel, voltage-dependent, gamma subunit 1" ID="ID_1364056091" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD4: 1.27-fold Up; FDR = 0.807; PValue = 0.503; mean CPM = 1.122; CD4 molecule" ID="ID_1464719338" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNA1S: 1.33-fold Down; FDR = 0.823; PValue = 0.522; mean CPM = 0.8938; calcium channel, voltage-dependent, L type, alpha 1S subunit" ID="ID_691931743" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNG7: 1.29-fold Down; FDR = 0.836; PValue = 0.541; mean CPM = 0.8254; calcium channel, voltage-dependent, gamma subunit 7" ID="ID_1395505877" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAQ: 1.05-fold Down; FDR = 0.889; PValue = 0.611; mean CPM = 9.623; Guanine nucleotide-binding protein G(Q) subunit alpha; Uncharacterized protein" ID="ID_1259216446" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNG3: 1.17-fold Up; FDR = 0.908; PValue = 0.683; mean CPM = 0.7891; calcium channel, voltage-dependent, gamma subunit 3" ID="ID_809418936" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FASLG: 1.2-fold Down; FDR = 0.941; PValue = 0.757; mean CPM = 0.8088; Fas ligand (TNF superfamily, member 6)" ID="ID_253035158" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016883: 1.11-fold Down; FDR = 0.97; PValue = 0.811; mean CPM = 0.8838; Uncharacterized protein" ID="ID_911441606" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG2: 1.06-fold Up; FDR = 0.985; PValue = 0.834; mean CPM = 2.248; phospholipase C, gamma 2 (phosphatidylinositol-specific)" ID="ID_572129677" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNA1G: 1.06-fold Down; FDR = 0.991; PValue = 0.844; mean CPM = 1.671; Uncharacterized protein" ID="ID_1530889049" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNB5: 1.04-fold Down; FDR = 1; PValue = 0.881; mean CPM = 1.533; guanine nucleotide binding protein (G protein), beta 5" ID="ID_1813351499" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNG2: 1.05-fold Up; FDR = 1; PValue = 0.915; mean CPM = 0.9147; calcium channel, voltage-dependent, gamma subunit 2" ID="ID_1904988568" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAQ: No Change; FDR = 1; PValue = 0.975; mean CPM = 15.20; guanine nucleotide binding protein (G protein), q polypeptide" ID="ID_1763169038" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNG4: 1.03-fold Up; FDR = 1; PValue = 0.993; mean CPM = 0.8322; calcium channel, voltage-dependent, gamma subunit 4" ID="ID_1272706513" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNG6: No Change; FDR = 1; PValue = 1; mean CPM = 0.7800; calcium channel, voltage-dependent, gamma subunit 6" ID="ID_1907636321" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="MIP1a / CCL3: FDR = 2.06e-08, PValue = 1.15e-08" ID="ID_936089309" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CCL2: 24.6-fold Up; FDR = 1.83e-15; PValue = 1.69e-17; mean CPM = 668.2; Macaca mulatta chemokine (C-C motif) ligand 2 (CCL2), mRNA." ID="ID_731942082" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2B: 3.54-fold Up; FDR = 1.24e-07; PValue = 7.07e-09; mean CPM = 5.971; PTK2B protein tyrosine kinase 2 beta" ID="ID_756918972" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_571355086" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALM3: 1.41-fold Down; FDR = 0.000714; PValue = 0.000115; mean CPM = 94.24; calmodulin 3 (phosphorylase kinase, delta)" ID="ID_523702292" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCR4: 4.65-fold Down; FDR = 0.00226; PValue = 0.000426; mean CPM = 2.073; chemokine (C-X-C motif) receptor 4" ID="ID_101027372" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG1: 1.31-fold Down; FDR = 0.00352; PValue = 0.000707; mean CPM = 53.66; phospholipase C, gamma 1" ID="ID_830531141" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_1338071526" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALM1: 1.18-fold Down; FDR = 0.104; PValue = 0.0368; mean CPM = 292.9; calmodulin 1 (phosphorylase kinase, delta)" ID="ID_164040396" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_86800169" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALM1: 1.11-fold Up; FDR = 0.343; PValue = 0.16; mean CPM = 412.7; Calmodulin; Uncharacterized protein" ID="ID_578698649" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_12435403" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR5: 1.56-fold Down; FDR = 0.487; PValue = 0.249; mean CPM = 1.064; chemokine (C-C motif) receptor 5" ID="ID_119132458" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL12: 1.27-fold Down; FDR = 0.488; PValue = 0.251; mean CPM = 4.383; chemokine (C-X-C motif) ligand 12" ID="ID_382987881" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCB: 1.86-fold Up; FDR = 0.727; PValue = 0.43; mean CPM = 0.8705; protein kinase C, beta" ID="ID_1093838549" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAQ: 1.05-fold Down; FDR = 0.889; PValue = 0.611; mean CPM = 9.623; Guanine nucleotide-binding protein G(Q) subunit alpha; Uncharacterized protein" ID="ID_847283462" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016883: 1.11-fold Down; FDR = 0.97; PValue = 0.811; mean CPM = 0.8838; Uncharacterized protein" ID="ID_599163568" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAQ: No Change; FDR = 1; PValue = 0.975; mean CPM = 15.20; guanine nucleotide binding protein (G protein), q polypeptide" ID="ID_1579501334" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="GITR: FDR = 2.69e-08, PValue = 1.54e-08" ID="ID_1572633122" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CASP5: 68-fold Up; FDR = 3.54e-19; PValue = 1.64e-21; mean CPM = 7.240; caspase 5, apoptosis-related cysteine peptidase" ID="ID_1637738494" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_677141519" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP4: 4.99-fold Up; FDR = 6.91e-12; PValue = 1.4e-13; mean CPM = 56.06; Caspase" ID="ID_584556638" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1241595691" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_609120333" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF1: 2.6-fold Down; FDR = 1.48e-05; PValue = 1.46e-06; mean CPM = 20.19; TNF receptor-associated factor 1" ID="ID_1166229914" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF18: 3.1-fold Down; FDR = 2.37e-05; PValue = 2.45e-06; mean CPM = 13.02; tumor necrosis factor (ligand) superfamily, member 18" ID="ID_671875256" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_982178339" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="REL: 1.46-fold Down; FDR = 0.00272; PValue = 0.000526; mean CPM = 10.17; v-rel avian reticuloendotheliosis viral oncogene homolog" ID="ID_68947600" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1581018166" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K14: 1.47-fold Down; FDR = 0.00704; PValue = 0.00157; mean CPM = 9.470; mitogen-activated protein kinase kinase kinase 14" ID="ID_1721171038" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP10: 1.81-fold Up; FDR = 0.0175; PValue = 0.0045; mean CPM = 2.876; caspase 10, apoptosis-related cysteine peptidase" ID="ID_858558241" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1671493878" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELB: 1.22-fold Down; FDR = 0.0606; PValue = 0.0193; mean CPM = 26.64; v-rel reticuloendotheliosis viral oncogene homolog B" ID="ID_317850401" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SIVA1: 1.16-fold Up; FDR = 0.105; PValue = 0.0372; mean CPM = 52.78; SIVA1, apoptosis-inducing factor" ID="ID_107564457" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_136053485" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP6: 1.17-fold Up; FDR = 0.197; PValue = 0.0807; mean CPM = 14.25; caspase 6, apoptosis-related cysteine peptidase" ID="ID_114741124" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP7: 1.15-fold Up; FDR = 0.218; PValue = 0.0916; mean CPM = 21.49; caspase 7, apoptosis-related cysteine peptidase" ID="ID_1851359963" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF18: 1.79-fold Down; FDR = 0.411; PValue = 0.201; mean CPM = 0.9222; tumor necrosis factor receptor superfamily, member 18" ID="ID_274443884" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF3: 1.07-fold Up; FDR = 0.611; PValue = 0.338; mean CPM = 34.56; TNF receptor-associated factor 3" ID="ID_112688299" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_1912775860" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_444738335" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP2: 1.05-fold Up; FDR = 0.906; PValue = 0.667; mean CPM = 12.88; caspase 2, apoptosis-related cysteine peptidase" ID="ID_1639526051" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKE: 1.03-fold Up; FDR = 0.929; PValue = 0.737; mean CPM = 21.61; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon" ID="ID_1049108601" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP9: 1.01-fold Up; FDR = 1; PValue = 0.908; mean CPM = 19.86; caspase 9, apoptosis-related cysteine peptidase" ID="ID_1415685913" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="MCP-1 / CCL2: FDR = 3.34e-08, PValue = 1.98e-08" ID="ID_918403151" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CCL2: 24.6-fold Up; FDR = 1.83e-15; PValue = 1.69e-17; mean CPM = 668.2; Macaca mulatta chemokine (C-C motif) ligand 2 (CCL2), mRNA." ID="ID_918906126" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_438750993" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_1742726489" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1123840233" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR2: 1.51-fold Up; FDR = 0.823; PValue = 0.523; mean CPM = 0.8333; chemokine (C-C motif) receptor 2" ID="ID_1444582585" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR4: 1.74-fold Up; FDR = 0.831; PValue = 0.533; mean CPM = 0.8536; chemokine (C-C motif) receptor 4" ID="ID_860102034" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLA2G4A: 1.08-fold Down; FDR = 0.836; PValue = 0.541; mean CPM = 40.53; phospholipase A2, group IVA (cytosolic, calcium-dependent)" ID="ID_65869769" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLA2G6: 1.03-fold Up; FDR = 0.958; PValue = 0.79; mean CPM = 10.46; phospholipase A2, group VI (cytosolic, calcium-independent)" ID="ID_931092504" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-18: FDR = 7.31e-08, PValue = 4.47e-08" ID="ID_528009048" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="IL18BP: 21.2-fold Up; FDR = 4.51e-22; PValue = 1.06e-24; mean CPM = 73.89; Macaca mulatta interleukin 18 binding protein (IL18BP), mRNA." ID="ID_283519395" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1200207719" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL18R1: 3.18-fold Down; FDR = 5.89e-06; PValue = 5.19e-07; mean CPM = 3.445; interleukin 18 receptor 1" ID="ID_195123992" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1R1: 1.6-fold Up; FDR = 3.35e-05; PValue = 3.61e-06; mean CPM = 123.7; interleukin 1 receptor, type I" ID="ID_87563271" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_1744559078" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_433869200" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K14: 1.47-fold Down; FDR = 0.00704; PValue = 0.00157; mean CPM = 9.470; mitogen-activated protein kinase kinase kinase 14" ID="ID_1159745534" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GADD45B: 1.49-fold Down; FDR = 0.0082; PValue = 0.00187; mean CPM = 175.6; growth arrest and DNA-damage-inducible, beta" ID="ID_1293159335" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12A: 2.09-fold Up; FDR = 0.00924; PValue = 0.00215; mean CPM = 2.872; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)" ID="ID_459963339" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL18: 1.5-fold Down; FDR = 0.00981; PValue = 0.0023; mean CPM = 6.489; interleukin 18 (interferon-gamma-inducing factor)" ID="ID_450343027" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GADD45G: 1.49-fold Up; FDR = 0.0173; PValue = 0.00444; mean CPM = 12.01; growth arrest and DNA-damage-inducible, gamma" ID="ID_1123214843" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBID: 1.47-fold Down; FDR = 0.0247; PValue = 0.0067; mean CPM = 6.446; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta" ID="ID_194679529" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIE: 1.3-fold Down; FDR = 0.0272; PValue = 0.00752; mean CPM = 16.93; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon" ID="ID_31213279" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL18RAP: 2.95-fold Down; FDR = 0.0275; PValue = 0.00761; mean CPM = 1.220; interleukin 18 receptor accessory protein" ID="ID_256385058" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_1360375438" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GADD45A: 1.22-fold Up; FDR = 0.0344; PValue = 0.00989; mean CPM = 127.8; growth arrest and DNA-damage-inducible, alpha" ID="ID_1167046338" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_188025113" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1RAP: 1.35-fold Up; FDR = 0.0392; PValue = 0.0116; mean CPM = 10.66; interleukin 1 receptor accessory protein" ID="ID_1342601699" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LEP: 1.67-fold Down; FDR = 0.0401; PValue = 0.0118; mean CPM = 63.70; leptin" ID="ID_1463350475" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIZ: 1.23-fold Up; FDR = 0.0949; PValue = 0.033; mean CPM = 91.08; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta" ID="ID_368348794" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_112622475" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_238133287" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1552294772" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_250535383" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK1: 1.04-fold Down; FDR = 0.885; PValue = 0.606; mean CPM = 41.54; interleukin-1 receptor-associated kinase 1" ID="ID_1063336670" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_1129766401" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12B: 1.07-fold Up; FDR = 0.983; PValue = 0.831; mean CPM = 0.8197; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)" ID="ID_22477849" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_670289945" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_358099068" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2: 1.03-fold Up; FDR = 1; PValue = 0.998; mean CPM = 0.7974; interleukin 2" ID="ID_49754768" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="NF-kappaB pathway: FDR = 4.08e-07, PValue = 2.63e-07" ID="ID_547978761" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TLR2: 8.94-fold Up; FDR = 6.97e-23; PValue = 1.25e-25; mean CPM = 18.41; toll-like receptor 2" ID="ID_886077149" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR3: 10.3-fold Up; FDR = 1.95e-21; PValue = 5.6e-24; mean CPM = 35.70; toll-like receptor 3" ID="ID_177918914" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_795658977" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICAM1: 24.6-fold Up; FDR = 2.39e-17; PValue = 1.64e-19; mean CPM = 232.4; intercellular adhesion molecule 1" ID="ID_716375543" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_1308393199" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF10: 44.5-fold Up; FDR = 2.83e-16; PValue = 2.4e-18; mean CPM = 6.029; Tumor necrosis factor ligand superfamily member 10 isoform 1; Uncharacterized protein" ID="ID_617937240" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL2: 24.6-fold Up; FDR = 1.83e-15; PValue = 1.69e-17; mean CPM = 668.2; Macaca mulatta chemokine (C-C motif) ligand 2 (CCL2), mRNA." ID="ID_886325748" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC2: 1.96-fold Up; FDR = 1.01e-10; PValue = 2.62e-12; mean CPM = 53.58; baculoviral IAP repeat-containing 2" ID="ID_1424122657" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR4: 3.45-fold Up; FDR = 3.1e-09; PValue = 1.19e-10; mean CPM = 7.456; Macaca mulatta toll-like receptor 4 (TLR4), mRNA." ID="ID_1875266638" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_764921200" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_911757418" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF1: 1.51-fold Up; FDR = 5.28e-06; PValue = 4.58e-07; mean CPM = 22.13; activating transcription factor 1" ID="ID_107210302" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL10: 1.55-fold Up; FDR = 5.92e-06; PValue = 5.22e-07; mean CPM = 21.83; B-cell CLL/lymphoma 10" ID="ID_1178501991" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFAIP3: 1.79-fold Up; FDR = 3.14e-05; PValue = 3.34e-06; mean CPM = 52.47; tumor necrosis factor, alpha-induced protein 3" ID="ID_827224036" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1R1: 1.6-fold Up; FDR = 3.35e-05; PValue = 3.61e-06; mean CPM = 123.7; interleukin 1 receptor, type I" ID="ID_1196434709" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HMOX1: 1.94-fold Up; FDR = 7.83e-05; PValue = 9.42e-06; mean CPM = 15.01; heme oxygenase (decycling) 1" ID="ID_1942311549" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_1317428755" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GJA1: 1.71-fold Up; FDR = 0.000117; PValue = 1.47e-05; mean CPM = 2600; gap junction protein, alpha 1, 43kDa" ID="ID_1114111621" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOD1: 1.63-fold Up; FDR = 0.000193; PValue = 2.61e-05; mean CPM = 58.36; nucleotide-binding oligomerization domain containing 1" ID="ID_111187744" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40: 2.76-fold Up; FDR = 0.00039; PValue = 5.79e-05; mean CPM = 9.139; CD40 molecule, TNF receptor superfamily member 5" ID="ID_1828467085" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_490180144" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRIM13: 1.38-fold Up; FDR = 0.0009; PValue = 0.000149; mean CPM = 19.75; tripartite motif-containing 13" ID="ID_508065344" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPM1A: 1.31-fold Up; FDR = 0.00101; PValue = 0.00017; mean CPM = 60.08; protein phosphatase, Mg2+/Mn2+ dependent, 1A" ID="ID_129334883" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC44A2: 1.31-fold Down; FDR = 0.00108; PValue = 0.000185; mean CPM = 154.3; solute carrier family 44, member 2" ID="ID_269480434" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="REL: 1.46-fold Down; FDR = 0.00272; PValue = 0.000526; mean CPM = 10.17; v-rel avian reticuloendotheliosis viral oncogene homolog" ID="ID_1584889443" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHOA: 1.28-fold Down; FDR = 0.00295; PValue = 0.000575; mean CPM = 277.8; ras homolog gene family, member A" ID="ID_1885844761" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBK1: 1.3-fold Up; FDR = 0.00337; PValue = 0.000674; mean CPM = 30.46; TANK-binding kinase 1" ID="ID_1494674720" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL20: 2.09-fold Up; FDR = 0.0108; PValue = 0.00256; mean CPM = 60.21; Macaca mulatta chemokine (C-C motif) ligand 20 (CCL20), mRNA." ID="ID_1666117856" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSF2: 2.96-fold Down; FDR = 0.0174; PValue = 0.00447; mean CPM = 73.98; colony stimulating factor 2 (granulocyte-macrophage)" ID="ID_1739268822" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HTR2B: 1.75-fold Up; FDR = 0.0194; PValue = 0.0051; mean CPM = 14.36; 5-hydroxytryptamine (serotonin) receptor 2B" ID="ID_1577154580" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL8: 2.33-fold Up; FDR = 0.0209; PValue = 0.00552; mean CPM = 2326; interleukin 8" ID="ID_1330072663" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1654554198" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_1678529568" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRADD: 1.22-fold Up; FDR = 0.0319; PValue = 0.00907; mean CPM = 34.75; TNFRSF1A-associated via death domain" ID="ID_871560619" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_519197645" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL3: 1.25-fold Up; FDR = 0.0559; PValue = 0.0175; mean CPM = 16.96; B-cell CLL/lymphoma 3" ID="ID_549420278" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELB: 1.22-fold Down; FDR = 0.0606; PValue = 0.0193; mean CPM = 26.64; v-rel reticuloendotheliosis viral oncogene homolog B" ID="ID_1679609597" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSF3: 2.55-fold Up; FDR = 0.0701; PValue = 0.023; mean CPM = 72.12; colony stimulating factor 3 (granulocyte)" ID="ID_948315681" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FADD: 1.18-fold Down; FDR = 0.0936; PValue = 0.0324; mean CPM = 30.89; Uncharacterized protein" ID="ID_912886329" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_522984373" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1745996585" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC20A1: 1.18-fold Up; FDR = 0.244; PValue = 0.105; mean CPM = 117.7; solute carrier family 20 (phosphate transporter), member 1" ID="ID_1399628771" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK2: 1.27-fold Down; FDR = 0.259; PValue = 0.113; mean CPM = 10.13; interleukin-1 receptor-associated kinase 2" ID="ID_226603535" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1A: 1.11-fold Up; FDR = 0.297; PValue = 0.134; mean CPM = 134.7; tumor necrosis factor receptor superfamily, member 1A" ID="ID_1439934632" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1A: 1.5-fold Up; FDR = 0.315; PValue = 0.144; mean CPM = 155.4; interleukin 1, alpha" ID="ID_1837428746" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGR1: 1.19-fold Down; FDR = 0.321; PValue = 0.147; mean CPM = 90.45; Early growth response protein 1; Uncharacterized protein" ID="ID_1164610975" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF10B: 1.13-fold Down; FDR = 0.343; PValue = 0.16; mean CPM = 40.59; tumor necrosis factor receptor superfamily, member 10b" ID="ID_1591143771" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MALT1: 1.11-fold Down; FDR = 0.35; PValue = 0.164; mean CPM = 42.89; mucosa associated lymphoid tissue lymphoma translocation gene 1" ID="ID_1593763760" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TICAM1: 1.11-fold Down; FDR = 0.398; PValue = 0.192; mean CPM = 26.73; toll-like receptor adaptor molecule 1" ID="ID_901266685" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="F2R: 1.1-fold Up; FDR = 0.458; PValue = 0.23; mean CPM = 35.05; coagulation factor II (thrombin) receptor" ID="ID_362420353" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD27: 1.52-fold Down; FDR = 0.547; PValue = 0.292; mean CPM = 1.004; CD27 molecule" ID="ID_392053049" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000000985: 1.2-fold Up; FDR = 0.569; PValue = 0.307; mean CPM = 11.32; Uncharacterized protein" ID="ID_86799668" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_599720244" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LTBR: 1.06-fold Down; FDR = 0.683; PValue = 0.394; mean CPM = 91.13; lymphotoxin beta receptor (TNFR superfamily, member 3)" ID="ID_253422012" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNB1: 1.79-fold Up; FDR = 0.731; PValue = 0.433; mean CPM = 0.8526; interferon, beta 1, fibroblast" ID="ID_226602279" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF10A: 1.06-fold Down; FDR = 0.732; PValue = 0.434; mean CPM = 42.75; tumor necrosis factor receptor superfamily, member 10a" ID="ID_81655311" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMED4: 1.06-fold Down; FDR = 0.74; PValue = 0.441; mean CPM = 69.78; transmembrane emp24 protein transport domain containing 4" ID="ID_16561175" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR6: 1.07-fold Down; FDR = 0.84; PValue = 0.546; mean CPM = 7.909; toll-like receptor 6" ID="ID_816963387" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1579419955" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR7: 1.37-fold Down; FDR = 0.878; PValue = 0.597; mean CPM = 0.8402; toll-like receptor 7" ID="ID_273373897" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK1: 1.04-fold Down; FDR = 0.885; PValue = 0.606; mean CPM = 41.54; interleukin-1 receptor-associated kinase 1" ID="ID_252131077" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_1922680986" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_1292184523" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF14: 1.16-fold Down; FDR = 0.903; PValue = 0.645; mean CPM = 0.7940; tumor necrosis factor (ligand) superfamily, member 14" ID="ID_1301915144" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKE: 1.03-fold Up; FDR = 0.929; PValue = 0.737; mean CPM = 21.61; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon" ID="ID_1358204016" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FASLG: 1.2-fold Down; FDR = 0.941; PValue = 0.757; mean CPM = 0.8088; Fas ligand (TNF superfamily, member 6)" ID="ID_511372450" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_1938381488" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR9: 1.01-fold Down; FDR = 1; PValue = 0.859; mean CPM = 21.45; Macaca mulatta toll-like receptor 9 (TLR9), mRNA." ID="ID_1817669525" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EDARADD: 1.04-fold Up; FDR = 1; PValue = 0.885; mean CPM = 1.496; EDAR-associated death domain" ID="ID_139566885" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR1: 1.02-fold Up; FDR = 1; PValue = 0.945; mean CPM = 1.221; toll-like receptor 1" ID="ID_677063775" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL10: 1.21-fold Down; FDR = 1; PValue = 0.964; mean CPM = 0.8614; interleukin 10" ID="ID_1182374153" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AGT: 1.02-fold Down; FDR = 1; PValue = 0.996; mean CPM = 0.8004; angiotensinogen (serpin peptidase inhibitor, clade A, member 8)" ID="ID_1931103754" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA1: No Change; FDR = 1; PValue = 0.998; mean CPM = 0.8014; interferon, alpha 1" ID="ID_47119273" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-21: FDR = 4.08e-07, PValue = 2.65e-07" ID="ID_1376714208" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_500794516" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_6353174" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_1180466623" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BID: 1.66-fold Up; FDR = 5.41e-09; PValue = 2.19e-10; mean CPM = 35.19; BH3 interacting domain death agonist" ID="ID_12392587" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1B: 1.64-fold Up; FDR = 1.22e-08; PValue = 5.39e-10; mean CPM = 32.96; Cyclin-dependent kinase inhibitor 1B; Uncharacterized protein" ID="ID_1506317303" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRDM1: 3.05-fold Up; FDR = 3.55e-08; PValue = 1.78e-09; mean CPM = 8.715; PR domain containing 1, with ZNF domain" ID="ID_1813010029" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_79369223" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L1: 1.51-fold Up; FDR = 9.13e-07; PValue = 6.52e-08; mean CPM = 66.15; Bcl-2-like protein 1; Bcl-2-like protein 1 isoform 1; Uncharacterized protein" ID="ID_1024085274" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17B: 4.36-fold Down; FDR = 2.84e-06; PValue = 2.29e-07; mean CPM = 1.984; interleukin 17B" ID="ID_1068476469" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PARP1: 1.46-fold Down; FDR = 0.00173; PValue = 0.000315; mean CPM = 46.95; poly (ADP-ribose) polymerase 1" ID="ID_1436492622" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK3: 2.31-fold Up; FDR = 0.00186; PValue = 0.000342; mean CPM = 2.154; Janus kinase 3" ID="ID_1302059968" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL20: 2.09-fold Up; FDR = 0.0108; PValue = 0.00256; mean CPM = 60.21; Macaca mulatta chemokine (C-C motif) ligand 20 (CCL20), mRNA." ID="ID_1344316214" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSF2: 2.96-fold Down; FDR = 0.0174; PValue = 0.00447; mean CPM = 73.98; colony stimulating factor 2 (granulocyte-macrophage)" ID="ID_282657596" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17D: 1.45-fold Down; FDR = 0.0235; PValue = 0.00633; mean CPM = 5.355; interleukin 17D" ID="ID_887671986" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL18RAP: 2.95-fold Down; FDR = 0.0275; PValue = 0.00761; mean CPM = 1.220; interleukin 18 receptor accessory protein" ID="ID_1633023662" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L11: 1.34-fold Up; FDR = 0.0609; PValue = 0.0195; mean CPM = 18.38; BCL2-like 11 (apoptosis facilitator)" ID="ID_27031214" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_773838234" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1095948302" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12RB2: 1.42-fold Down; FDR = 0.299; PValue = 0.135; mean CPM = 1.728; interleukin 12 receptor, beta 2" ID="ID_773582420" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL21R: 1.56-fold Down; FDR = 0.534; PValue = 0.282; mean CPM = 1.021; interleukin 21 receptor" ID="ID_885372240" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_654909125" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL6: 1.06-fold Down; FDR = 0.837; PValue = 0.542; mean CPM = 64.49; B-cell CLL/lymphoma 6" ID="ID_760548839" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_1197000308" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL25: 1.24-fold Down; FDR = 0.899; PValue = 0.631; mean CPM = 0.7976; interleukin 25" ID="ID_701460415" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17A: 1.12-fold Up; FDR = 0.911; PValue = 0.706; mean CPM = 0.7895; interleukin 17A" ID="ID_1228578350" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2RA: 1.08-fold Up; FDR = 0.945; PValue = 0.766; mean CPM = 0.8493; interleukin 2 receptor, alpha" ID="ID_919871219" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL17F: 1.11-fold Down; FDR = 0.948; PValue = 0.771; mean CPM = 1.150; interleukin 17F" ID="ID_1794771186" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL21: 1.04-fold Up; FDR = 0.948; PValue = 0.773; mean CPM = 0.8164; interleukin 21" ID="ID_1622132927" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBX21: 1.09-fold Up; FDR = 0.972; PValue = 0.813; mean CPM = 0.9978; T-box 21" ID="ID_554630717" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="TNF superfamily pathway: FDR = 1.64e-06, PValue = 1.09e-06" ID="ID_266686298" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_1951067391" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF14: 4.66-fold Up; FDR = 2.46e-16; PValue = 2.07e-18; mean CPM = 36.12; Macaca mulatta tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) (TNFRSF14), mRNA." ID="ID_1587402959" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_1411750096" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSIP1: 1.94-fold Up; FDR = 3.71e-07; PValue = 2.38e-08; mean CPM = 84.28; PC4 and SFRS1 interacting protein 1" ID="ID_130113032" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1885190264" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1860033638" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1415087700" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1B: 2.24-fold Up; FDR = 2.68e-06; PValue = 2.16e-07; mean CPM = 19.44; tumor necrosis factor receptor superfamily, member 1B" ID="ID_1467292891" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAMLG: 1.43-fold Up; FDR = 1.38e-05; PValue = 1.34e-06; mean CPM = 35.09; calcium modulating ligand" ID="ID_1084122728" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF1: 2.6-fold Down; FDR = 1.48e-05; PValue = 1.46e-06; mean CPM = 20.19; TNF receptor-associated factor 1" ID="ID_147104969" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF10D: 1.84-fold Down; FDR = 5.9e-05; PValue = 6.84e-06; mean CPM = 32.06; tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain" ID="ID_662448614" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_569968564" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40: 2.76-fold Up; FDR = 0.00039; PValue = 5.79e-05; mean CPM = 9.139; CD40 molecule, TNF receptor superfamily member 5" ID="ID_1132456321" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF6B: 1.73-fold Down; FDR = 0.000702; PValue = 0.000113; mean CPM = 6.143; tumor necrosis factor receptor superfamily, member 6b, decoy" ID="ID_1306109442" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NR4A1: 1.74-fold Down; FDR = 0.00108; PValue = 0.000184; mean CPM = 312.6; nuclear receptor subfamily 4, group A, member 1" ID="ID_1903988686" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF8: 2.27-fold Down; FDR = 0.00264; PValue = 0.000509; mean CPM = 2.103; tumor necrosis factor receptor superfamily, member 8" ID="ID_1413783002" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELT: 2.44-fold Down; FDR = 0.0028; PValue = 0.000543; mean CPM = 3.224; RELT tumor necrosis factor receptor" ID="ID_367280410" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF12A: 1.24-fold Down; FDR = 0.0133; PValue = 0.00326; mean CPM = 478.0; tumor necrosis factor receptor superfamily, member 12A" ID="ID_1505411503" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP10: 1.81-fold Up; FDR = 0.0175; PValue = 0.0045; mean CPM = 2.876; caspase 10, apoptosis-related cysteine peptidase" ID="ID_1968741098" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_559732748" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRADD: 1.22-fold Up; FDR = 0.0319; PValue = 0.00907; mean CPM = 34.75; TNFRSF1A-associated via death domain" ID="ID_1409360820" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF4: 1.21-fold Down; FDR = 0.037; PValue = 0.0108; mean CPM = 29.95; TNF receptor-associated factor 4" ID="ID_1791211623" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_442751930" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF19: 1.33-fold Up; FDR = 0.0618; PValue = 0.0198; mean CPM = 94.66; tumor necrosis factor receptor superfamily, member 19" ID="ID_887670128" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FADD: 1.18-fold Down; FDR = 0.0936; PValue = 0.0324; mean CPM = 30.89; Uncharacterized protein" ID="ID_141134852" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF11B: 1.31-fold Down; FDR = 0.121; PValue = 0.0439; mean CPM = 722.1; Uncharacterized protein" ID="ID_208512859" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LYPLA1: 1.15-fold Up; FDR = 0.193; PValue = 0.0789; mean CPM = 23.69; Uncharacterized protein" ID="ID_338687990" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP6: 1.17-fold Up; FDR = 0.197; PValue = 0.0807; mean CPM = 14.25; caspase 6, apoptosis-related cysteine peptidase" ID="ID_1094867226" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP7: 1.15-fold Up; FDR = 0.218; PValue = 0.0916; mean CPM = 21.49; caspase 7, apoptosis-related cysteine peptidase" ID="ID_385827252" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NGFR: 1.72-fold Down; FDR = 0.285; PValue = 0.127; mean CPM = 1.174; nerve growth factor receptor" ID="ID_448950148" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1A: 1.11-fold Up; FDR = 0.297; PValue = 0.134; mean CPM = 134.7; tumor necrosis factor receptor superfamily, member 1A" ID="ID_1724566347" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_246761800" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF10B: 1.13-fold Down; FDR = 0.343; PValue = 0.16; mean CPM = 40.59; tumor necrosis factor receptor superfamily, member 10b" ID="ID_1843513337" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1249857452" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF18: 1.79-fold Down; FDR = 0.411; PValue = 0.201; mean CPM = 0.9222; tumor necrosis factor receptor superfamily, member 18" ID="ID_778966503" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_575336074" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_567441303" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_1084494102" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD27: 1.52-fold Down; FDR = 0.547; PValue = 0.292; mean CPM = 1.004; CD27 molecule" ID="ID_726969635" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NR2C1: 1.09-fold Up; FDR = 0.55; PValue = 0.294; mean CPM = 21.04; nuclear receptor subfamily 2, group C, member 1" ID="ID_644627763" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF3: 1.07-fold Up; FDR = 0.611; PValue = 0.338; mean CPM = 34.56; TNF receptor-associated factor 3" ID="ID_1746147040" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF11A: 1.4-fold Down; FDR = 0.676; PValue = 0.388; mean CPM = 0.9723; tumor necrosis factor receptor superfamily, member 11a, NFKB activator" ID="ID_822665236" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LTBR: 1.06-fold Down; FDR = 0.683; PValue = 0.394; mean CPM = 91.13; lymphotoxin beta receptor (TNFR superfamily, member 3)" ID="ID_716365233" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF10A: 1.06-fold Down; FDR = 0.732; PValue = 0.434; mean CPM = 42.75; tumor necrosis factor receptor superfamily, member 10a" ID="ID_797789495" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF4: 1.36-fold Down; FDR = 0.743; PValue = 0.444; mean CPM = 0.8892; tumor necrosis factor receptor superfamily, member 4" ID="ID_803258606" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_415751094" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF25: 1.2-fold Up; FDR = 0.772; PValue = 0.471; mean CPM = 1.687; tumor necrosis factor receptor superfamily, member 25" ID="ID_282756705" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF14: 1.16-fold Down; FDR = 0.903; PValue = 0.645; mean CPM = 0.7940; tumor necrosis factor (ligand) superfamily, member 14" ID="ID_1540767280" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP2: 1.05-fold Up; FDR = 0.906; PValue = 0.667; mean CPM = 12.88; caspase 2, apoptosis-related cysteine peptidase" ID="ID_1208272508" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF9: 1.28-fold Down; FDR = 0.911; PValue = 0.7; mean CPM = 0.8318; tumor necrosis factor receptor superfamily, member 9" ID="ID_1009430173" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF21: 1.07-fold Down; FDR = 0.922; PValue = 0.726; mean CPM = 6.488; tumor necrosis factor receptor superfamily, member 21" ID="ID_1816778128" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF17: 1.08-fold Down; FDR = 0.954; PValue = 0.783; mean CPM = 1.418; tumor necrosis factor receptor superfamily, member 17" ID="ID_944707963" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF13B: 1.06-fold Up; FDR = 0.954; PValue = 0.784; mean CPM = 0.8104; tumor necrosis factor receptor superfamily, member 13B" ID="ID_1393590882" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP9: 1.01-fold Up; FDR = 1; PValue = 0.908; mean CPM = 19.86; caspase 9, apoptosis-related cysteine peptidase" ID="ID_289383149" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LTB: 1.01-fold Up; FDR = 1; PValue = 0.935; mean CPM = 0.8459; Lymphotoxin-beta (LT-beta)(Tumor necrosis factor C)(TNF-C)(Tumor necrosis factor ligand superfamily member 3)" ID="ID_103297837" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000006973: 1.09-fold Down; FDR = 1; PValue = 0.938; mean CPM = 0.8165; Uncharacterized protein" ID="ID_1837921407" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LYPLA1: 1.04-fold Up; FDR = 1; PValue = 0.966; mean CPM = 0.8610; lysophospholipase I" ID="ID_930659243" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000007111: 1.12-fold Down; FDR = 1; PValue = 0.993; mean CPM = 0.8245; Uncharacterized protein" ID="ID_297714529" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-10: FDR = 9.4e-06, PValue = 6.48e-06" ID="ID_891519337" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="STAT2: 2.67-fold Up; FDR = 8.02e-19; PValue = 4.03e-21; mean CPM = 185.6; signal transducer and activator of transcription 2, 113kDa" ID="ID_1488237838" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_144494420" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5A: 2.28-fold Up; FDR = 6.87e-14; PValue = 8.58e-16; mean CPM = 21.55; signal transducer and activator of transcription 5A" ID="ID_1067367288" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_475561467" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND3: 2.27-fold Down; FDR = 8.38e-11; PValue = 2.15e-12; mean CPM = 86.90; cyclin D3" ID="ID_1805876132" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR4: 3.45-fold Up; FDR = 3.1e-09; PValue = 1.19e-10; mean CPM = 7.456; Macaca mulatta toll-like receptor 4 (TLR4), mRNA." ID="ID_865316365" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_711117131" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD14: 2.75-fold Down; FDR = 6.54e-07; PValue = 4.46e-08; mean CPM = 5.195; CD14 molecule" ID="ID_51562274" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L1: 1.51-fold Up; FDR = 9.13e-07; PValue = 6.52e-08; mean CPM = 66.15; Bcl-2-like protein 1; Bcl-2-like protein 1 isoform 1; Uncharacterized protein" ID="ID_1030020806" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_635160545" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT4: 1.79-fold Up; FDR = 2.3e-05; PValue = 2.36e-06; mean CPM = 26.79; signal transducer and activator of transcription 4" ID="ID_1536499000" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HMOX1: 1.94-fold Up; FDR = 7.83e-05; PValue = 9.42e-06; mean CPM = 15.01; heme oxygenase (decycling) 1" ID="ID_870630368" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_416670836" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TIA1: 1.35-fold Up; FDR = 0.000361; PValue = 5.3e-05; mean CPM = 39.12; TIA1 cytotoxic granule-associated RNA binding protein" ID="ID_426695026" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS3: 1.69-fold Up; FDR = 0.000994; PValue = 0.000167; mean CPM = 37.76; suppressor of cytokine signaling 3" ID="ID_1260739170" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="REL: 1.46-fold Down; FDR = 0.00272; PValue = 0.000526; mean CPM = 10.17; v-rel avian reticuloendotheliosis viral oncogene homolog" ID="ID_1855142642" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYK2: 1.24-fold Down; FDR = 0.0142; PValue = 0.00354; mean CPM = 42.58; tyrosine kinase 2" ID="ID_1622532694" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BLVRA: 1.23-fold Up; FDR = 0.0288; PValue = 0.00801; mean CPM = 47.29; biliverdin reductase A" ID="ID_729621011" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIM1: 1.39-fold Down; FDR = 0.0325; PValue = 0.00926; mean CPM = 21.11; pim-1 oncogene" ID="ID_53351532" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_737477892" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELB: 1.22-fold Down; FDR = 0.0606; PValue = 0.0193; mean CPM = 26.64; v-rel reticuloendotheliosis viral oncogene homolog B" ID="ID_628612320" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_1153202212" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT6: 1.18-fold Up; FDR = 0.0727; PValue = 0.024; mean CPM = 217.5; signal transducer and activator of transcription 6, interleukin-4 induced" ID="ID_509939604" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_773929340" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND1: 1.17-fold Up; FDR = 0.121; PValue = 0.0443; mean CPM = 867.3; cyclin D1" ID="ID_333893637" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1A: 1.5-fold Up; FDR = 0.315; PValue = 0.144; mean CPM = 155.4; interleukin 1, alpha" ID="ID_729233401" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND2: 1.2-fold Up; FDR = 0.335; PValue = 0.155; mean CPM = 76.91; cyclin D2" ID="ID_1036795220" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL23A: 1.39-fold Up; FDR = 0.348; PValue = 0.163; mean CPM = 4.542; interleukin 23, alpha subunit p19" ID="ID_1129515722" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_417325400" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL10RA: 1.55-fold Down; FDR = 0.516; PValue = 0.269; mean CPM = 0.9545; interleukin 10 receptor, alpha" ID="ID_222602035" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_581886318" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPKAPK2: 1.06-fold Down; FDR = 0.733; PValue = 0.435; mean CPM = 82.16; mitogen-activated protein kinase-activated protein kinase 2" ID="ID_1080193107" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_1186081854" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BLVRB: 1.03-fold Up; FDR = 0.908; PValue = 0.676; mean CPM = 62.92; biliverdin reductase B (flavin reductase (NADPH))" ID="ID_171368971" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADAMTS13: 1.01-fold Up; FDR = 1; PValue = 0.935; mean CPM = 5.092; ADAM metallopeptidase with thrombospondin type 1 motif, 13" ID="ID_641332428" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL10: 1.21-fold Down; FDR = 1; PValue = 0.964; mean CPM = 0.8614; interleukin 10" ID="ID_967702206" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="NLR signaling: FDR = 9.4e-06, PValue = 6.61e-06" ID="ID_641709373" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CASP5: 68-fold Up; FDR = 3.54e-19; PValue = 1.64e-21; mean CPM = 7.240; caspase 5, apoptosis-related cysteine peptidase" ID="ID_1675882321" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_449002229" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK2: 3.75-fold Up; FDR = 6.1e-16; PValue = 5.38e-18; mean CPM = 68.21; receptor-interacting serine-threonine kinase 2" ID="ID_1824214398" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL2: 24.6-fold Up; FDR = 1.83e-15; PValue = 1.69e-17; mean CPM = 668.2; Macaca mulatta chemokine (C-C motif) ligand 2 (CCL2), mRNA." ID="ID_381397431" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CARD6: 2.33-fold Up; FDR = 1.15e-12; PValue = 1.89e-14; mean CPM = 30.09; caspase recruitment domain family, member 6" ID="ID_830933506" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CARD8: 2.48-fold Up; FDR = 2.44e-11; PValue = 5.59e-13; mean CPM = 14.84; caspase recruitment domain family, member 8" ID="ID_1343159452" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC2: 1.96-fold Up; FDR = 1.01e-10; PValue = 2.62e-12; mean CPM = 53.58; baculoviral IAP repeat-containing 2" ID="ID_1377755904" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL13: 12.3-fold Up; FDR = 4.33e-10; PValue = 1.35e-11; mean CPM = 3.824; chemokine (C-C motif) ligand 13" ID="ID_1716361685" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CARD8: 2.02-fold Up; FDR = 1.41e-09; PValue = 4.93e-11; mean CPM = 15.89; caspase recruitment domain family, member 8" ID="ID_1540974207" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL7: 8.24-fold Up; FDR = 6.67e-09; PValue = 2.75e-10; mean CPM = 8.249; chemokine (C-C motif) ligand 7" ID="ID_725981523" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_503896430" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLRC4: 6.6-fold Up; FDR = 8.52e-08; PValue = 4.67e-09; mean CPM = 3.347; NLR family, CARD domain containing 4" ID="ID_138096255" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL5: 6.74-fold Up; FDR = 2.65e-07; PValue = 1.64e-08; mean CPM = 30.35; chemokine (C-C motif) ligand 5" ID="ID_741505392" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC3: 2.79-fold Up; FDR = 1.74e-06; PValue = 1.32e-07; mean CPM = 95.34; baculoviral IAP repeat-containing 3" ID="ID_669729373" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_288374302" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL11: 6.86-fold Up; FDR = 2.69e-05; PValue = 2.82e-06; mean CPM = 4.204; chemokine (C-C motif) ligand 11" ID="ID_1586494855" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFAIP3: 1.79-fold Up; FDR = 3.14e-05; PValue = 3.34e-06; mean CPM = 52.47; tumor necrosis factor, alpha-induced protein 3" ID="ID_280973472" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90AA1: 1.41-fold Up; FDR = 4.17e-05; PValue = 4.62e-06; mean CPM = 609.6; heat shock protein 90kDa alpha (cytosolic), class A member 2" ID="ID_1849298331" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CARD9: 1.53-fold Up; FDR = 9.57e-05; PValue = 1.18e-05; mean CPM = 16.72; caspase recruitment domain family, member 9" ID="ID_701709797" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP2: 1.45-fold Up; FDR = 0.000179; PValue = 2.4e-05; mean CPM = 65.31; TGF-beta activated kinase 1/MAP3K7 binding protein 2" ID="ID_1921661699" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOD1: 1.63-fold Up; FDR = 0.000193; PValue = 2.61e-05; mean CPM = 58.36; nucleotide-binding oligomerization domain containing 1" ID="ID_1796065209" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SUGT1: 1.35-fold Up; FDR = 0.000193; PValue = 2.61e-05; mean CPM = 54.75; SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)" ID="ID_1472736846" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP3: 1.5-fold Up; FDR = 0.000276; PValue = 3.92e-05; mean CPM = 11.67; TGF-beta activated kinase 1/MAP3K7 binding protein 3" ID="ID_190135837" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_762119331" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90B1: 1.28-fold Down; FDR = 0.00538; PValue = 0.00115; mean CPM = 1017; heat shock protein 90kDa beta (Grp94), member 1" ID="ID_1003796522" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_968174536" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL1: 2.18-fold Up; FDR = 0.00609; PValue = 0.00133; mean CPM = 45.92; chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)" ID="ID_1377476285" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL8: 3.3-fold Up; FDR = 0.00609; PValue = 0.00133; mean CPM = 1.313; chemokine (C-C motif) ligand 8" ID="ID_207545283" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL18: 1.5-fold Down; FDR = 0.00981; PValue = 0.0023; mean CPM = 6.489; interleukin 18 (interferon-gamma-inducing factor)" ID="ID_491279022" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_121904302" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL8: 2.33-fold Up; FDR = 0.0209; PValue = 0.00552; mean CPM = 2326; interleukin 8" ID="ID_1569288962" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1291210232" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_534486701" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_1826143553" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XIAP: 1.17-fold Up; FDR = 0.177; PValue = 0.0706; mean CPM = 19.21; X-linked inhibitor of apoptosis" ID="ID_1406962075" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PYCARD: 1.38-fold Down; FDR = 0.241; PValue = 0.103; mean CPM = 3.110; PYD and CARD domain containing" ID="ID_484557905" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLRP3: 1.84-fold Down; FDR = 0.32; PValue = 0.147; mean CPM = 0.9630; NLR family, pyrin domain containing 3" ID="ID_1361110475" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP1: 1.12-fold Down; FDR = 0.351; PValue = 0.165; mean CPM = 17.96; TGF-beta activated kinase 1/MAP3K7 binding protein 1" ID="ID_616720520" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_925056901" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1185130905" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK12: 1.19-fold Down; FDR = 0.422; PValue = 0.208; mean CPM = 6.569; mitogen-activated protein kinase 12" ID="ID_1404307099" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1147484701" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK13: 1.22-fold Down; FDR = 0.536; PValue = 0.284; mean CPM = 3.100; mitogen-activated protein kinase 13" ID="ID_106454805" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90AB1: 1.07-fold Down; FDR = 0.652; PValue = 0.369; mean CPM = 905.8; heat shock protein 90kDa alpha (cytosolic), class B member 1" ID="ID_646119976" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_1595015282" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90AA1: 1.8-fold Up; FDR = 0.749; PValue = 0.449; mean CPM = 0.8328; heat shock protein 90kDa alpha (cytosolic), class A member 1" ID="ID_1412907666" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MEFV: 1.13-fold Up; FDR = 0.813; PValue = 0.51; mean CPM = 6.740; Mediterranean fever" ID="ID_788573460" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_355604326" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOD2: 1.17-fold Up; FDR = 0.866; PValue = 0.583; mean CPM = 1.911; nucleotide-binding oligomerization domain containing 2" ID="ID_1608788566" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_641489022" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_578918622" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRIP6: 1.01-fold Down; FDR = 1; PValue = 0.92; mean CPM = 125.6; thyroid hormone receptor interactor 6" ID="ID_1979361044" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSTPIP1: 1.03-fold Down; FDR = 1; PValue = 0.929; mean CPM = 1.615; proline-serine-threonine phosphatase interacting protein 1" ID="ID_445231143" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_1194134913" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-1R1: FDR = 1.11e-05, PValue = 8e-06" ID="ID_990278906" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CCL2: 24.6-fold Up; FDR = 1.83e-15; PValue = 1.69e-17; mean CPM = 668.2; Macaca mulatta chemokine (C-C motif) ligand 2 (CCL2), mRNA." ID="ID_337168496" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PELI1: 2-fold Up; FDR = 5.5e-09; PValue = 2.23e-10; mean CPM = 30.48; pellino homolog 1 (Drosophila)" ID="ID_411239373" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK4: 1.8-fold Up; FDR = 3.31e-08; PValue = 1.64e-09; mean CPM = 12.89; interleukin-1 receptor-associated kinase 4" ID="ID_1034097091" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1770144609" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1072640887" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_546682513" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K3: 1.45-fold Down; FDR = 7.01e-06; PValue = 6.34e-07; mean CPM = 180.1; mitogen-activated protein kinase kinase 3" ID="ID_1185473856" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_197245674" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1R1: 1.6-fold Up; FDR = 3.35e-05; PValue = 3.61e-06; mean CPM = 123.7; interleukin 1 receptor, type I" ID="ID_21673969" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP2: 1.45-fold Up; FDR = 0.000179; PValue = 2.4e-05; mean CPM = 65.31; TGF-beta activated kinase 1/MAP3K7 binding protein 2" ID="ID_835910656" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP3: 1.5-fold Up; FDR = 0.000276; PValue = 3.92e-05; mean CPM = 11.67; TGF-beta activated kinase 1/MAP3K7 binding protein 3" ID="ID_1451249774" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF2: 1.34-fold Up; FDR = 0.000403; PValue = 6.01e-05; mean CPM = 39.83; activating transcription factor 2" ID="ID_1612860731" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_733736179" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TOLLIP: 1.36-fold Down; FDR = 0.000551; PValue = 8.57e-05; mean CPM = 28.79; Uncharacterized protein" ID="ID_798010945" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="REL: 1.46-fold Down; FDR = 0.00272; PValue = 0.000526; mean CPM = 10.17; v-rel avian reticuloendotheliosis viral oncogene homolog" ID="ID_300735910" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG1: 1.31-fold Down; FDR = 0.00352; PValue = 0.000707; mean CPM = 53.66; phospholipase C, gamma 1" ID="ID_1420272130" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1022018704" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK3: 1.54-fold Up; FDR = 0.00653; PValue = 0.00144; mean CPM = 19.97; interleukin-1 receptor-associated kinase 3" ID="ID_633937110" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K14: 1.47-fold Down; FDR = 0.00704; PValue = 0.00157; mean CPM = 9.470; mitogen-activated protein kinase kinase kinase 14" ID="ID_1291870500" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K3: 1.26-fold Down; FDR = 0.00786; PValue = 0.00178; mean CPM = 38.85; mitogen-activated protein kinase kinase kinase 3" ID="ID_1679510479" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCZ: 1.51-fold Up; FDR = 0.0152; PValue = 0.00381; mean CPM = 10.46; protein kinase C, zeta" ID="ID_1149921456" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PELI2: 1.41-fold Down; FDR = 0.0196; PValue = 0.00515; mean CPM = 6.598; pellino homolog 2 (Drosophila)" ID="ID_1374469650" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_729857835" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1958523021" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ECSIT: 1.2-fold Down; FDR = 0.0358; PValue = 0.0104; mean CPM = 54.27; ECSIT homolog (Drosophila)" ID="ID_1553257208" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1306348824" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1RAP: 1.35-fold Up; FDR = 0.0392; PValue = 0.0116; mean CPM = 10.66; interleukin 1 receptor accessory protein" ID="ID_1745400389" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_338476956" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_1580904937" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1786281611" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK2: 1.27-fold Down; FDR = 0.259; PValue = 0.113; mean CPM = 10.13; interleukin-1 receptor-associated kinase 2" ID="ID_1293987724" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SQSTM1: 1.19-fold Down; FDR = 0.289; PValue = 0.129; mean CPM = 270.1; sequestosome 1" ID="ID_686509317" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1A: 1.5-fold Up; FDR = 0.315; PValue = 0.144; mean CPM = 155.4; interleukin 1, alpha" ID="ID_1058084311" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP1: 1.12-fold Down; FDR = 0.351; PValue = 0.165; mean CPM = 17.96; TGF-beta activated kinase 1/MAP3K7 binding protein 1" ID="ID_941574069" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1050713463" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1042364971" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_773309723" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="UBE2V1: 1.11-fold Down; FDR = 0.482; PValue = 0.246; mean CPM = 13.47; ubiquitin-conjugating enzyme E2 variant 1" ID="ID_499812347" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000038917: 1.08-fold Up; FDR = 0.591; PValue = 0.323; mean CPM = 33.13; Uncharacterized protein" ID="ID_1499190788" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_564257202" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPKAPK2: 1.06-fold Down; FDR = 0.733; PValue = 0.435; mean CPM = 82.16; mitogen-activated protein kinase-activated protein kinase 2" ID="ID_1646471446" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_132104146" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1291489686" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK1: 1.04-fold Down; FDR = 0.885; PValue = 0.606; mean CPM = 41.54; interleukin-1 receptor-associated kinase 1" ID="ID_991074141" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K2: 1.03-fold Up; FDR = 0.924; PValue = 0.73; mean CPM = 40.64; mitogen-activated protein kinase kinase kinase 2" ID="ID_1627646300" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_1651148816" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_1101940470" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPB2: 1.05-fold Down; FDR = 1; PValue = 0.889; mean CPM = 0.9668; heat shock 27kDa protein 2" ID="ID_411821070" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_875249657" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="TGF-beta: FDR = 1.24e-05, PValue = 9.22e-06" ID="ID_1208346394" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TGFB3: 4.82-fold Down; FDR = 1.82e-12; PValue = 3.09e-14; mean CPM = 9.911; transforming growth factor, beta 3" ID="ID_194463315" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_1670228336" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZFYVE9: 1.55-fold Up; FDR = 2.39e-08; PValue = 1.15e-09; mean CPM = 52.92; zinc finger, FYVE domain containing 9" ID="ID_383258749" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_895414988" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K3: 1.45-fold Down; FDR = 7.01e-06; PValue = 6.34e-07; mean CPM = 180.1; mitogen-activated protein kinase kinase 3" ID="ID_323659870" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1868320397" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF2: 1.34-fold Up; FDR = 0.000403; PValue = 6.01e-05; mean CPM = 39.83; activating transcription factor 2" ID="ID_1831843666" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD3: 1.38-fold Up; FDR = 0.000573; PValue = 8.94e-05; mean CPM = 114.9; SMAD family member 3" ID="ID_1415008443" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHOA: 1.28-fold Down; FDR = 0.00295; PValue = 0.000575; mean CPM = 277.8; ras homolog gene family, member A" ID="ID_934064557" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD7: 1.33-fold Down; FDR = 0.00568; PValue = 0.00123; mean CPM = 67.59; SMAD family member 7" ID="ID_1713206967" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_1913629099" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD2: 1.2-fold Up; FDR = 0.034; PValue = 0.00976; mean CPM = 57.10; SMAD family member 2" ID="ID_65352364" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFBR1: 1.2-fold Up; FDR = 0.037; PValue = 0.0108; mean CPM = 90.92; transforming growth factor, beta receptor 1" ID="ID_1692682586" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFBR2: 1.19-fold Up; FDR = 0.0643; PValue = 0.0208; mean CPM = 350.8; transforming growth factor, beta receptor II (70/80kDa)" ID="ID_1141376246" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS2: 1.17-fold Up; FDR = 0.1; PValue = 0.0353; mean CPM = 31.79; son of sevenless homolog 2 (Drosophila)" ID="ID_1573349530" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1217584078" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XIAP: 1.17-fold Up; FDR = 0.177; PValue = 0.0706; mean CPM = 19.21; X-linked inhibitor of apoptosis" ID="ID_1701950209" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_698882995" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_577143039" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EP300: 1.11-fold Up; FDR = 0.312; PValue = 0.142; mean CPM = 162.8; E1A binding protein p300" ID="ID_1411856938" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP1: 1.12-fold Down; FDR = 0.351; PValue = 0.165; mean CPM = 17.96; TGF-beta activated kinase 1/MAP3K7 binding protein 1" ID="ID_1877758025" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APC: 1.1-fold Down; FDR = 0.367; PValue = 0.174; mean CPM = 127.5; adenomatous polyposis coli" ID="ID_1220837495" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_333467948" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1986094393" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP4K1: 1.26-fold Up; FDR = 0.879; PValue = 0.598; mean CPM = 0.9281; mitogen-activated protein kinase kinase kinase kinase 1" ID="ID_1697034513" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NR2C2: 1.04-fold Down; FDR = 0.903; PValue = 0.641; mean CPM = 18.87; nuclear receptor subfamily 2, group C, member 2" ID="ID_318192076" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB2: 1.05-fold Down; FDR = 0.903; PValue = 0.655; mean CPM = 110.8; transforming growth factor, beta 2" ID="ID_1698188823" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD4: 1.03-fold Down; FDR = 0.906; PValue = 0.666; mean CPM = 43.02; SMAD family member 4" ID="ID_1283208079" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB1: 1.02-fold Down; FDR = 0.936; PValue = 0.749; mean CPM = 62.61; transforming growth factor, beta 1" ID="ID_533412921" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R4: 1.02-fold Down; FDR = 0.943; PValue = 0.763; mean CPM = 93.45; protein phosphatase 2A activator, regulatory subunit 4" ID="ID_624879936" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SKIL: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 66.09; SKI-like oncogene" ID="ID_1109074490" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_907033014" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREBBP: 1.01-fold Down; FDR = 0.993; PValue = 0.847; mean CPM = 137.7; CREB binding protein" ID="ID_1226726154" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_1130660743" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDH1: 1.06-fold Down; FDR = 1; PValue = 0.899; mean CPM = 0.8823; cadherin 1, type 1, E-cadherin (epithelial)" ID="ID_1606263830" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Eotaxin / CCL11: FDR = 4.99e-05, PValue = 3.85e-05" ID="ID_1144500547" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="GNG10: 2.27-fold Up; FDR = 1.24e-13; PValue = 1.66e-15; mean CPM = 24.29; guanine nucleotide binding protein (G protein), gamma 10" ID="ID_1021913280" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL13: 12.3-fold Up; FDR = 4.33e-10; PValue = 1.35e-11; mean CPM = 3.824; chemokine (C-C motif) ligand 13" ID="ID_945299987" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL7: 8.24-fold Up; FDR = 6.67e-09; PValue = 2.75e-10; mean CPM = 8.249; chemokine (C-C motif) ligand 7" ID="ID_1944878607" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CFL2: 1.88-fold Down; FDR = 1.06e-08; PValue = 4.59e-10; mean CPM = 58.30; cofilin 2 (muscle)" ID="ID_1347587009" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL5: 6.74-fold Up; FDR = 2.65e-07; PValue = 1.64e-08; mean CPM = 30.35; chemokine (C-C motif) ligand 5" ID="ID_1030356688" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG11: 1.65-fold Up; FDR = 2.71e-07; PValue = 1.68e-08; mean CPM = 86.60; guanine nucleotide binding protein (G protein), gamma 11" ID="ID_1477481134" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYLK: 2.29-fold Down; FDR = 1.02e-06; PValue = 7.45e-08; mean CPM = 128.3; myosin light chain kinase" ID="ID_1191778345" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCB1: 1.71-fold Up; FDR = 1.31e-06; PValue = 9.73e-08; mean CPM = 34.36; phospholipase C, beta 1 (phosphoinositide-specific)" ID="ID_879644618" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1210322923" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_1007088990" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_745315" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL11: 6.86-fold Up; FDR = 2.69e-05; PValue = 2.82e-06; mean CPM = 4.204; chemokine (C-C motif) ligand 11" ID="ID_888820982" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAI1: 1.47-fold Up; FDR = 5.94e-05; PValue = 6.9e-06; mean CPM = 97.19; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1" ID="ID_127946545" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACA: 1.36-fold Down; FDR = 0.000167; PValue = 2.22e-05; mean CPM = 37.75; protein kinase, cAMP-dependent, catalytic, alpha" ID="ID_318893003" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_586356648" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PREX1: 1.34-fold Down; FDR = 0.000592; PValue = 9.28e-05; mean CPM = 89.02; phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1" ID="ID_1683305402" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYBA: 1.34-fold Up; FDR = 0.00107; PValue = 0.000183; mean CPM = 376.6; cytochrome b-245, alpha polypeptide" ID="ID_128976244" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAS1: 1.31-fold Down; FDR = 0.00158; PValue = 0.000283; mean CPM = 564.9; Uncharacterized protein" ID="ID_1320046683" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PFN2: 1.41-fold Up; FDR = 0.00199; PValue = 0.000369; mean CPM = 25.56; Profilin" ID="ID_1716521823" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHOA: 1.28-fold Down; FDR = 0.00295; PValue = 0.000575; mean CPM = 277.8; ras homolog gene family, member A" ID="ID_1595814546" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP1R12B: 1.52-fold Down; FDR = 0.00383; PValue = 0.000782; mean CPM = 15.41; protein phosphatase 1, regulatory (inhibitor) subunit 12B" ID="ID_451151896" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG12: 1.31-fold Up; FDR = 0.00387; PValue = 0.000792; mean CPM = 24.97; guanine nucleotide binding protein (G protein), gamma 12" ID="ID_118005866" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYL12B: 1.28-fold Up; FDR = 0.00408; PValue = 0.00084; mean CPM = 372.0; myosin, light chain 12B, regulatory" ID="ID_1980523041" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LIMK2: 1.51-fold Down; FDR = 0.00509; PValue = 0.00108; mean CPM = 60.03; LIM domain kinase 2" ID="ID_1314397130" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL8: 3.3-fold Up; FDR = 0.00609; PValue = 0.00133; mean CPM = 1.313; chemokine (C-C motif) ligand 8" ID="ID_1370307604" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYB5R3: 1.25-fold Down; FDR = 0.00983; PValue = 0.0023; mean CPM = 422.4; cytochrome b5 reductase 3" ID="ID_1791004710" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARF6: 1.24-fold Down; FDR = 0.0106; PValue = 0.00251; mean CPM = 87.11; ADP-ribosylation factor 6" ID="ID_497053830" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCZ: 1.51-fold Up; FDR = 0.0152; PValue = 0.00381; mean CPM = 10.46; protein kinase C, zeta" ID="ID_499607018" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1719338773" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DOCK2: 1.4-fold Up; FDR = 0.0216; PValue = 0.00573; mean CPM = 37.89; dedicator of cytokinesis 2" ID="ID_1764475402" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_632976152" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INPP5D: 1.88-fold Down; FDR = 0.0276; PValue = 0.00763; mean CPM = 5.690; inositol polyphosphate-5-phosphatase, 145kDa" ID="ID_1097480380" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC2: 2.96-fold Up; FDR = 0.0309; PValue = 0.00872; mean CPM = 0.9737; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)" ID="ID_1282554869" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDPK1: 1.24-fold Down; FDR = 0.0361; PValue = 0.0105; mean CPM = 17.53; 3-phosphoinositide dependent protein kinase-1" ID="ID_1784268393" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCB2: 3.68-fold Down; FDR = 0.0481; PValue = 0.0147; mean CPM = 1.557; Uncharacterized protein" ID="ID_1611102459" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DAG1: 1.54-fold Down; FDR = 0.0661; PValue = 0.0214; mean CPM = 3.013; dystroglycan 1 (dystrophin-associated glycoprotein 1)" ID="ID_1462949400" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_745460710" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYTH4: 2.72-fold Down; FDR = 0.0737; PValue = 0.0244; mean CPM = 0.8845; cytohesin 4" ID="ID_1837387329" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TIAM1: 1.23-fold Up; FDR = 0.0747; PValue = 0.0248; mean CPM = 38.38; T-cell lymphoma invasion and metastasis 1" ID="ID_1127916698" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG2: 1.64-fold Up; FDR = 0.117; PValue = 0.0421; mean CPM = 2.320; guanine nucleotide binding protein (G protein), gamma 2" ID="ID_682701047" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG3: 1.6-fold Down; FDR = 0.155; PValue = 0.0601; mean CPM = 1.706; guanine nucleotide binding protein (G protein), gamma 3" ID="ID_1630920175" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLD1: 1.24-fold Down; FDR = 0.162; PValue = 0.0634; mean CPM = 15.80; phospholipase D1, phosphatidylcholine-specific" ID="ID_1907681710" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTEN: 1.14-fold Up; FDR = 0.166; PValue = 0.065; mean CPM = 89.60; phosphatase and tensin homolog" ID="ID_345052599" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ROCK2: 1.14-fold Up; FDR = 0.166; PValue = 0.065; mean CPM = 247.7; Rho-associated, coiled-coil containing protein kinase 2" ID="ID_31754291" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP1R12A: 1.14-fold Up; FDR = 0.167; PValue = 0.0655; mean CPM = 282.7; protein phosphatase 1, regulatory (inhibitor) subunit 12A" ID="ID_873763776" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITPR3: 1.13-fold Up; FDR = 0.194; PValue = 0.079; mean CPM = 157.4; inositol 1,4,5-triphosphate receptor, type 3" ID="ID_1263043064" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_330114676" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_217201038" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PFN1: 1.12-fold Down; FDR = 0.337; PValue = 0.156; mean CPM = 965.8; profilin 1" ID="ID_290385765" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG7: 1.75-fold Down; FDR = 0.366; PValue = 0.174; mean CPM = 0.9647; guanine nucleotide binding protein (G protein), gamma 7" ID="ID_417588573" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_606323510" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2: 1.1-fold Up; FDR = 0.394; PValue = 0.191; mean CPM = 102.5; PTK2 protein tyrosine kinase 2" ID="ID_1051195889" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1343455569" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL26: 1.74-fold Down; FDR = 0.423; PValue = 0.208; mean CPM = 0.8756; chemokine (C-C motif) ligand 26" ID="ID_1378479503" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACTR2: 1.09-fold Up; FDR = 0.44; PValue = 0.219; mean CPM = 263.8; ARP2 actin-related protein 2 homolog (yeast)" ID="ID_259177127" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_444108732" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGR: 1.63-fold Up; FDR = 0.516; PValue = 0.269; mean CPM = 1.191; Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog" ID="ID_172282703" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG4: 1.65-fold Down; FDR = 0.524; PValue = 0.275; mean CPM = 0.8771; guanine nucleotide binding protein (G protein), gamma 4" ID="ID_403594776" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCF2: 1.29-fold Up; FDR = 0.525; PValue = 0.276; mean CPM = 2.178; Uncharacterized protein" ID="ID_1019713981" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_1588402292" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNB1: 1.08-fold Down; FDR = 0.565; PValue = 0.305; mean CPM = 299.4; guanine nucleotide binding protein (G protein), beta polypeptide 1" ID="ID_1100864267" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP1CB: 1.08-fold Up; FDR = 0.566; PValue = 0.306; mean CPM = 108.6; protein phosphatase 1, catalytic subunit, beta isozyme" ID="ID_1240680525" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYBB: 1.52-fold Up; FDR = 0.705; PValue = 0.412; mean CPM = 0.9872; cytochrome b-245, beta polypeptide" ID="ID_1639387024" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCB: 1.86-fold Up; FDR = 0.727; PValue = 0.43; mean CPM = 0.8705; protein kinase C, beta" ID="ID_1118415028" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG13: 1.67-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8104; guanine nucleotide binding protein (G protein), gamma 13" ID="ID_1898516649" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WAS: 1.37-fold Down; FDR = 0.771; PValue = 0.469; mean CPM = 0.9085; Wiskott-Aldrich syndrome" ID="ID_15718326" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACG: 1.51-fold Down; FDR = 0.795; PValue = 0.491; mean CPM = 0.8026; protein kinase, cAMP-dependent, catalytic, gamma" ID="ID_614174015" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HCK: 1.3-fold Down; FDR = 0.797; PValue = 0.494; mean CPM = 0.9272; Uncharacterized protein" ID="ID_688730751" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV1: 1.25-fold Down; FDR = 0.858; PValue = 0.572; mean CPM = 0.9515; vav 1 guanine nucleotide exchange factor" ID="ID_1650317336" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1827816054" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAQ: 1.05-fold Down; FDR = 0.889; PValue = 0.611; mean CPM = 9.623; Guanine nucleotide-binding protein G(Q) subunit alpha; Uncharacterized protein" ID="ID_1204689373" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BMX: 1.42-fold Down; FDR = 0.898; PValue = 0.625; mean CPM = 0.8398; BMX non-receptor tyrosine kinase" ID="ID_1560280040" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PFN3: 1.24-fold Down; FDR = 0.899; PValue = 0.631; mean CPM = 0.8001; profilin 3" ID="ID_527863817" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PFN3: 1.14-fold Down; FDR = 0.903; PValue = 0.658; mean CPM = 0.7895; Uncharacterized protein" ID="ID_1867564472" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCR3: 1.43-fold Up; FDR = 0.906; PValue = 0.665; mean CPM = 0.8397; chemokine (C-C motif) receptor 3" ID="ID_1363688184" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACTR3: 1.13-fold Up; FDR = 0.908; PValue = 0.681; mean CPM = 0.7943; ARP3 actin-related protein 3 homolog (yeast)" ID="ID_1950850516" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYL2: 1.15-fold Up; FDR = 0.909; PValue = 0.69; mean CPM = 0.7911; myosin, light chain 2, regulatory, cardiac, slow" ID="ID_1135498891" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACB: 1.03-fold Up; FDR = 0.911; PValue = 0.694; mean CPM = 30.10; protein kinase, cAMP-dependent, catalytic, beta" ID="ID_229685064" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LIMK2: 1.14-fold Down; FDR = 0.911; PValue = 0.697; mean CPM = 0.7896; LIM domain kinase 2" ID="ID_1600625608" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK1: 1.03-fold Down; FDR = 0.911; PValue = 0.705; mean CPM = 18.65; p21 protein (Cdc42/Rac)-activated kinase 1" ID="ID_897379544" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KAT5: 1.03-fold Down; FDR = 0.916; PValue = 0.715; mean CPM = 42.22; K(lysine) acetyltransferase 5" ID="ID_466107717" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_905698878" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG5: 1.02-fold Down; FDR = 0.952; PValue = 0.781; mean CPM = 21.93; guanine nucleotide binding protein (G protein), gamma 5" ID="ID_640466161" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMEM55B: 1.02-fold Up; FDR = 0.963; PValue = 0.798; mean CPM = 15.78; transmembrane protein 55B" ID="ID_1801668431" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_1244488917" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYH6: 1.11-fold Up; FDR = 0.975; PValue = 0.817; mean CPM = 1.001; myosin, heavy chain 6, cardiac muscle, alpha" ID="ID_542676725" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG8: 1.11-fold Down; FDR = 0.989; PValue = 0.84; mean CPM = 0.8494; guanine nucleotide binding protein (G protein), gamma 8" ID="ID_1387207457" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_708455085" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNGT1: 1.05-fold Up; FDR = 1; PValue = 0.871; mean CPM = 0.8362; guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1" ID="ID_616748377" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOX1: 1.11-fold Up; FDR = 1; PValue = 0.922; mean CPM = 0.8469; NADPH oxidase 1" ID="ID_31570233" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BTK: No Change; FDR = 1; PValue = 0.965; mean CPM = 0.8336; Bruton agammaglobulinemia tyrosine kinase" ID="ID_1542771646" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAQ: No Change; FDR = 1; PValue = 0.975; mean CPM = 15.20; guanine nucleotide binding protein (G protein), q polypeptide" ID="ID_891514728" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV2: No Change; FDR = 1; PValue = 0.976; mean CPM = 25.65; vav 2 guanine nucleotide exchange factor" ID="ID_1236448319" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SFTPD: 1.03-fold Down; FDR = 1; PValue = 0.982; mean CPM = 0.8042; surfactant protein D" ID="ID_1140330418" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL24: 1.01-fold Up; FDR = 1; PValue = 0.999; mean CPM = 0.8072; Uncharacterized protein" ID="ID_1318913222" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="p53: FDR = 4.99e-05, PValue = 3.88e-05" ID="ID_152446539" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_51472719" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RRM2B: 2.34-fold Up; FDR = 5.88e-13; PValue = 9.04e-15; mean CPM = 96.48; ribonucleotide reductase M2 B (TP53 inducible)" ID="ID_1456937260" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PMAIP1: 8.66-fold Up; FDR = 1.12e-12; PValue = 1.84e-14; mean CPM = 31.02; Phorbol-12-myristate-13-acetate-induced protein 1; Uncharacterized protein" ID="ID_1440669926" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND3: 2.27-fold Down; FDR = 8.38e-11; PValue = 2.15e-12; mean CPM = 86.90; cyclin D3" ID="ID_1279332663" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BID: 1.66-fold Up; FDR = 5.41e-09; PValue = 2.19e-10; mean CPM = 35.19; BH3 interacting domain death agonist" ID="ID_1294354940" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RCHY1: 2.04-fold Up; FDR = 1.35e-08; PValue = 6.04e-10; mean CPM = 25.49; ring finger and CHY zinc finger domain containing 1" ID="ID_764999735" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZMAT3: 1.69-fold Up; FDR = 1.51e-07; PValue = 8.85e-09; mean CPM = 49.10; zinc finger, matrin type 3" ID="ID_990490730" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNG2: 1.58-fold Up; FDR = 2.55e-07; PValue = 1.56e-08; mean CPM = 45.06; cyclin G2" ID="ID_1174779684" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_918402772" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THBS1: 2.74-fold Down; FDR = 1.68e-06; PValue = 1.28e-07; mean CPM = 25785; thrombospondin 1" ID="ID_146368686" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1: 5.76-fold Down; FDR = 6.73e-06; PValue = 6.04e-07; mean CPM = 1.536; insulin-like growth factor 1 (somatomedin C)" ID="ID_1327061247" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGFBP3: 2.13-fold Down; FDR = 6.87e-06; PValue = 6.19e-07; mean CPM = 3776; insulin-like growth factor binding protein 3" ID="ID_671514036" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TSC2: 1.44-fold Down; FDR = 1e-05; PValue = 9.42e-07; mean CPM = 124.0; tuberous sclerosis 2" ID="ID_1294097938" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNG1: 1.38-fold Up; FDR = 6.77e-05; PValue = 8.01e-06; mean CPM = 149.9; cyclin G1" ID="ID_1537098725" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP53I3: 1.62-fold Down; FDR = 0.000105; PValue = 1.3e-05; mean CPM = 21.59; tumor protein p53 inducible protein 3" ID="ID_256663443" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SESN2: 1.54-fold Up; FDR = 0.000955; PValue = 0.00016; mean CPM = 76.08; sestrin 2" ID="ID_537821813" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHISA5: 1.45-fold Up; FDR = 0.00115; PValue = 0.000198; mean CPM = 12.01; shisa homolog 5 (Xenopus laevis)" ID="ID_376886609" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHISA5: 1.3-fold Up; FDR = 0.00148; PValue = 0.000264; mean CPM = 172.3; shisa family member 5" ID="ID_1894505838" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SERPINE1: 1.58-fold Down; FDR = 0.00232; PValue = 0.000438; mean CPM = 5294; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1" ID="ID_514123353" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SESN3: 1.52-fold Up; FDR = 0.00256; PValue = 0.000491; mean CPM = 443.2; sestrin 3" ID="ID_1577815476" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD82: 1.42-fold Up; FDR = 0.0045; PValue = 0.00094; mean CPM = 43.78; CD82 molecule" ID="ID_441048155" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MDM2: 1.32-fold Up; FDR = 0.00555; PValue = 0.00119; mean CPM = 148.6; Uncharacterized protein" ID="ID_1276397800" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GADD45B: 1.49-fold Down; FDR = 0.0082; PValue = 0.00187; mean CPM = 175.6; growth arrest and DNA-damage-inducible, beta" ID="ID_1312692472" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GTSE1: 1.58-fold Down; FDR = 0.00855; PValue = 0.00196; mean CPM = 10.71; G-2 and S-phase expressed 1" ID="ID_307411744" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SIAH1: 1.32-fold Up; FDR = 0.0104; PValue = 0.00245; mean CPM = 14.33; seven in absentia homolog 1 (Drosophila)" ID="ID_151258661" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GADD45G: 1.49-fold Up; FDR = 0.0173; PValue = 0.00444; mean CPM = 12.01; growth arrest and DNA-damage-inducible, gamma" ID="ID_1311316099" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK2: 1.23-fold Down; FDR = 0.0194; PValue = 0.00507; mean CPM = 36.76; cyclin-dependent kinase 2" ID="ID_466158370" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHEK2: 1.38-fold Up; FDR = 0.0228; PValue = 0.00613; mean CPM = 20.56; checkpoint kinase 2" ID="ID_828918978" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GADD45A: 1.22-fold Up; FDR = 0.0344; PValue = 0.00989; mean CPM = 127.8; growth arrest and DNA-damage-inducible, alpha" ID="ID_1402034804" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP73: 2.3-fold Down; FDR = 0.0601; PValue = 0.0192; mean CPM = 1.058; tumor protein p73" ID="ID_982133791" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNB1: 1.39-fold Down; FDR = 0.0958; PValue = 0.0333; mean CPM = 44.87; cyclin B1" ID="ID_1276930509" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND1: 1.17-fold Up; FDR = 0.121; PValue = 0.0443; mean CPM = 867.3; cyclin D1" ID="ID_1255416278" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTEN: 1.14-fold Up; FDR = 0.166; PValue = 0.065; mean CPM = 89.60; phosphatase and tensin homolog" ID="ID_935266961" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LRDD: 1.2-fold Down; FDR = 0.207; PValue = 0.0859; mean CPM = 25.64; leucine-rich repeats and death domain containing" ID="ID_708760135" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PERP: 1.32-fold Down; FDR = 0.208; PValue = 0.0863; mean CPM = 3.279; Uncharacterized protein" ID="ID_906920836" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000039103: 1.67-fold Down; FDR = 0.221; PValue = 0.0927; mean CPM = 1.310; Uncharacterized protein" ID="ID_420217200" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNB2: 1.24-fold Down; FDR = 0.237; PValue = 0.101; mean CPM = 15.12; cyclin B2" ID="ID_1788543968" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNE1: 1.2-fold Up; FDR = 0.278; PValue = 0.123; mean CPM = 6.609; cyclin E1" ID="ID_1275734869" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1A: 1.16-fold Down; FDR = 0.28; PValue = 0.124; mean CPM = 363.2; Cyclin-dependent kinase inhibitor 1; Uncharacterized protein" ID="ID_1814258262" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK6: 1.18-fold Down; FDR = 0.301; PValue = 0.136; mean CPM = 26.51; cyclin-dependent kinase 6" ID="ID_1513168654" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SFN: 1.69-fold Down; FDR = 0.304; PValue = 0.138; mean CPM = 1.084; stratifin" ID="ID_26382679" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND2: 1.2-fold Up; FDR = 0.335; PValue = 0.155; mean CPM = 76.91; cyclin D2" ID="ID_69358339" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF10B: 1.13-fold Down; FDR = 0.343; PValue = 0.16; mean CPM = 40.59; tumor necrosis factor receptor superfamily, member 10b" ID="ID_1266489712" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP53: 1.11-fold Down; FDR = 0.364; PValue = 0.172; mean CPM = 33.25; tumor protein p53" ID="ID_289133726" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EI24: 1.11-fold Down; FDR = 0.408; PValue = 0.199; mean CPM = 19.02; etoposide induced 2.4 mRNA" ID="ID_1905133756" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STEAP3: 1.11-fold Down; FDR = 0.449; PValue = 0.224; mean CPM = 154.9; STEAP family member 3" ID="ID_995051842" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAI1: 1.74-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 0.8744; brain-specific angiogenesis inhibitor 1" ID="ID_1986879852" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DDB2: 1.07-fold Down; FDR = 0.626; PValue = 0.349; mean CPM = 69.08; damage-specific DNA binding protein 2, 48kDa" ID="ID_88163106" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MDM4: 1.07-fold Up; FDR = 0.632; PValue = 0.354; mean CPM = 28.16; Mdm4 p53 binding protein homolog (mouse)" ID="ID_413331883" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATM: 1.06-fold Down; FDR = 0.67; PValue = 0.383; mean CPM = 65.17; ataxia telangiectasia mutated" ID="ID_1084840467" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RRM2: 1.18-fold Down; FDR = 0.675; PValue = 0.387; mean CPM = 63.27; ribonucleotide reductase M2" ID="ID_1288547367" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SERPINB5: 1.44-fold Down; FDR = 0.716; PValue = 0.42; mean CPM = 0.8736; Peptidase inhibitor 5; Uncharacterized protein" ID="ID_39481109" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_565861046" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPRM: 1.38-fold Down; FDR = 0.807; PValue = 0.504; mean CPM = 0.8749; reprimo, TP53 dependent G2 arrest mediator candidate" ID="ID_524282117" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAX: 1.05-fold Up; FDR = 0.809; PValue = 0.506; mean CPM = 162.4; Uncharacterized protein" ID="ID_525034415" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APAF1: 1.05-fold Down; FDR = 0.837; PValue = 0.543; mean CPM = 32.11; apoptotic peptidase activating factor 1" ID="ID_348158325" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYCS: 1.05-fold Up; FDR = 0.854; PValue = 0.565; mean CPM = 93.43; cytochrome c, somatic" ID="ID_1275862694" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000040219: 1.08-fold Up; FDR = 0.86; PValue = 0.575; mean CPM = 8.818; Uncharacterized protein" ID="ID_1655126603" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPM1D: 1.05-fold Up; FDR = 0.884; PValue = 0.604; mean CPM = 14.38; Protein phosphatase 1D; Uncharacterized protein" ID="ID_845932123" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK4: 1.04-fold Up; FDR = 0.899; PValue = 0.626; mean CPM = 65.45; cyclin-dependent kinase 4" ID="ID_1653546866" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK1: 1.07-fold Up; FDR = 0.908; PValue = 0.682; mean CPM = 14.72; Uncharacterized protein" ID="ID_1752920953" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RFWD2: 1.03-fold Up; FDR = 0.911; PValue = 0.705; mean CPM = 36.86; ring finger and WD repeat domain 2" ID="ID_494072310" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BBC3: 1.04-fold Down; FDR = 0.948; PValue = 0.77; mean CPM = 7.586; BCL2 binding component 3" ID="ID_1179077297" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNE2: 1.05-fold Up; FDR = 0.962; PValue = 0.796; mean CPM = 6.415; cyclin E2" ID="ID_241270755" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000009289: 1.07-fold Up; FDR = 0.963; PValue = 0.798; mean CPM = 2.536; Uncharacterized protein" ID="ID_1141854227" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PERP: 1.08-fold Down; FDR = 1; PValue = 0.864; mean CPM = 0.9252; PERP, TP53 apoptosis effector" ID="ID_935205949" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP9: 1.01-fold Up; FDR = 1; PValue = 0.908; mean CPM = 19.86; caspase 9, apoptosis-related cysteine peptidase" ID="ID_774498542" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SESN1: 1.01-fold Up; FDR = 1; PValue = 0.939; mean CPM = 8.816; sestrin 1" ID="ID_1558942834" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Vitamin D: FDR = 5.47e-05, PValue = 4.36e-05" ID="ID_987542916" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="HDAC5: 1.72-fold Down; FDR = 2.07e-09; PValue = 7.53e-11; mean CPM = 122.7; histone deacetylase 5" ID="ID_524385291" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MEF2D: 1.73-fold Down; FDR = 2.02e-08; PValue = 9.5e-10; mean CPM = 61.43; myocyte enhancer factor 2D" ID="ID_717438910" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMARCAL1: 1.57-fold Up; FDR = 2.55e-08; PValue = 1.23e-09; mean CPM = 35.29; Uncharacterized protein" ID="ID_362522508" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC9: 4.18-fold Down; FDR = 2.74e-08; PValue = 1.34e-09; mean CPM = 25.34; histone deacetylase 9" ID="ID_193390309" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMARCA5: 1.51-fold Up; FDR = 1.43e-07; PValue = 8.31e-09; mean CPM = 184.6; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5" ID="ID_1040308008" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMARCA4: 1.49-fold Down; FDR = 3.19e-07; PValue = 2.01e-08; mean CPM = 157.3; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4" ID="ID_484313973" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1422385151" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1825133651" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMARCD3: 1.5-fold Down; FDR = 6.15e-06; PValue = 5.46e-07; mean CPM = 36.08; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3" ID="ID_266425985" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1735860630" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC7: 1.43-fold Down; FDR = 5.36e-05; PValue = 6.14e-06; mean CPM = 25.32; Uncharacterized protein" ID="ID_818940930" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPP1: 2.25-fold Down; FDR = 7.74e-05; PValue = 9.29e-06; mean CPM = 35.33; secreted phosphoprotein 1" ID="ID_1439137339" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCE: 1.73-fold Up; FDR = 0.00013; PValue = 1.67e-05; mean CPM = 10.87; protein kinase C, epsilon" ID="ID_4421710" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACA: 1.36-fold Down; FDR = 0.000167; PValue = 2.22e-05; mean CPM = 37.75; protein kinase, cAMP-dependent, catalytic, alpha" ID="ID_298398765" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000028518: 1.35-fold Down; FDR = 0.000199; PValue = 2.72e-05; mean CPM = 42.49" ID="ID_107844941" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HLTF: 1.37-fold Up; FDR = 0.000275; PValue = 3.91e-05; mean CPM = 48.37; helicase-like transcription factor" ID="ID_435983901" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SIN3A: 1.33-fold Up; FDR = 0.000459; PValue = 6.96e-05; mean CPM = 56.62; SIN3 homolog A, transcription regulator (yeast)" ID="ID_535683084" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMARCC1: 1.31-fold Down; FDR = 0.000832; PValue = 0.000136; mean CPM = 55.44; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1" ID="ID_511595257" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000039874: 1.3-fold Up; FDR = 0.001; PValue = 0.000168; mean CPM = 80.13; Uncharacterized protein" ID="ID_1825433486" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCH: 1.98-fold Down; FDR = 0.00105; PValue = 0.000179; mean CPM = 3.182; protein kinase C, eta" ID="ID_1219461495" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000031974: 1.38-fold Down; FDR = 0.00112; PValue = 0.000192; mean CPM = 16.65; Uncharacterized protein" ID="ID_1530010927" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMARCD1: 1.31-fold Up; FDR = 0.00181; PValue = 0.000332; mean CPM = 31.72; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1" ID="ID_1109886894" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GTF2B: 1.3-fold Up; FDR = 0.0019; PValue = 0.000351; mean CPM = 38.87; general transcription factor IIB" ID="ID_686214285" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKD3: 1.29-fold Up; FDR = 0.00214; PValue = 0.0004; mean CPM = 43.43; protein kinase D3" ID="ID_1616904496" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG1: 1.31-fold Down; FDR = 0.00352; PValue = 0.000707; mean CPM = 53.66; phospholipase C, gamma 1" ID="ID_1413354305" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAZ1B: 1.27-fold Up; FDR = 0.00357; PValue = 0.00072; mean CPM = 170.6; bromodomain adjacent to zinc finger domain, 1B" ID="ID_1035014281" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC4: 1.38-fold Down; FDR = 0.00526; PValue = 0.00112; mean CPM = 48.60; histone deacetylase 4" ID="ID_369484461" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHAF1A: 1.42-fold Down; FDR = 0.0138; PValue = 0.00339; mean CPM = 19.62; Uncharacterized protein" ID="ID_1768134992" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCZ: 1.51-fold Up; FDR = 0.0152; PValue = 0.00381; mean CPM = 10.46; protein kinase C, zeta" ID="ID_1139700792" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC1: 1.25-fold Up; FDR = 0.0159; PValue = 0.00403; mean CPM = 27.51; histone deacetylase 1" ID="ID_407245903" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1714982817" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SUPT16H: 1.21-fold Up; FDR = 0.0239; PValue = 0.00646; mean CPM = 153.4; suppressor of Ty 16 homolog (S. cerevisiae)" ID="ID_667330457" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB1: 1.21-fold Up; FDR = 0.0313; PValue = 0.00884; mean CPM = 36.07; cAMP responsive element binding protein 1" ID="ID_71147291" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC6: 1.21-fold Down; FDR = 0.0436; PValue = 0.0131; mean CPM = 30.86; histone deacetylase 6" ID="ID_1120822883" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYP2R1: 1.51-fold Up; FDR = 0.0616; PValue = 0.0197; mean CPM = 3.294; cytochrome P450, family 2, subfamily R, polypeptide 1" ID="ID_1174853111" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RXRA: 1.18-fold Down; FDR = 0.077; PValue = 0.0257; mean CPM = 35.60; retinoid X receptor, alpha" ID="ID_743603893" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACTL6A: 1.18-fold Up; FDR = 0.099; PValue = 0.0346; mean CPM = 28.90; actin-like 6A" ID="ID_1123871972" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC2: 1.15-fold Up; FDR = 0.115; PValue = 0.0414; mean CPM = 93.64; histone deacetylase 2" ID="ID_138366720" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KDM1A: 1.14-fold Down; FDR = 0.177; PValue = 0.0705; mean CPM = 77.01; lysine (K)-specific demethylase 1A" ID="ID_607433163" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASGRP1: 1.4-fold Down; FDR = 0.224; PValue = 0.0945; mean CPM = 2.348; RAS guanyl releasing protein 1 (calcium and DAG-regulated)" ID="ID_1799473662" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1A: 1.16-fold Down; FDR = 0.28; PValue = 0.124; mean CPM = 363.2; Cyclin-dependent kinase inhibitor 1; Uncharacterized protein" ID="ID_1753393536" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EP300: 1.11-fold Up; FDR = 0.312; PValue = 0.142; mean CPM = 162.8; E1A binding protein p300" ID="ID_1564368147" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_1670860444" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYP24A1: 1.82-fold Down; FDR = 0.34; PValue = 0.158; mean CPM = 1.131; cytochrome P450, family 24, subfamily A, polypeptide 1" ID="ID_1006314473" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MEF2C: 1.24-fold Down; FDR = 0.357; PValue = 0.168; mean CPM = 6.816; myocyte enhancer factor 2C" ID="ID_855071474" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMARCC2: 1.1-fold Down; FDR = 0.371; PValue = 0.176; mean CPM = 86.26; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2" ID="ID_659458107" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_847145232" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1001724056" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC10: 1.1-fold Down; FDR = 0.489; PValue = 0.251; mean CPM = 21.21; Uncharacterized protein" ID="ID_160113982" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCI: 1.08-fold Up; FDR = 0.518; PValue = 0.271; mean CPM = 47.99; protein kinase C, iota" ID="ID_1627932895" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCQ: 1.56-fold Up; FDR = 0.522; PValue = 0.274; mean CPM = 1.047; Uncharacterized protein" ID="ID_221245914" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_1633014918" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCG: 1.47-fold Down; FDR = 0.609; PValue = 0.336; mean CPM = 0.9297; protein kinase C, gamma" ID="ID_691547665" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMARCA2: 1.07-fold Down; FDR = 0.654; PValue = 0.37; mean CPM = 65.89; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2" ID="ID_1283094102" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCD: 1.06-fold Up; FDR = 0.696; PValue = 0.404; mean CPM = 37.45; protein kinase C, delta" ID="ID_1492483273" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCB: 1.86-fold Up; FDR = 0.727; PValue = 0.43; mean CPM = 0.8705; protein kinase C, beta" ID="ID_1253677327" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC8: 1.06-fold Up; FDR = 0.76; PValue = 0.459; mean CPM = 20.83; histone deacetylase 8" ID="ID_1582317795" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GC: 1.53-fold Up; FDR = 0.789; PValue = 0.486; mean CPM = 0.8281; Uncharacterized protein" ID="ID_1679376470" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACG: 1.51-fold Down; FDR = 0.795; PValue = 0.491; mean CPM = 0.8026; protein kinase, cAMP-dependent, catalytic, gamma" ID="ID_1019949919" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYP27B1: 1.09-fold Up; FDR = 0.856; PValue = 0.569; mean CPM = 3.584; cytochrome P450, family 27, subfamily B, polypeptide 1" ID="ID_1805376610" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_934233790" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACTL6B: 1.43-fold Down; FDR = 0.9; PValue = 0.636; mean CPM = 0.8538; actin-like 6B" ID="ID_1549451762" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARID1B: 1.04-fold Down; FDR = 0.908; PValue = 0.683; mean CPM = 80.39; AT rich interactive domain 1B (SWI1-like)" ID="ID_1773392814" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMARCA1: 1.04-fold Down; FDR = 0.908; PValue = 0.683; mean CPM = 122.1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1" ID="ID_1784622160" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACB: 1.03-fold Up; FDR = 0.911; PValue = 0.694; mean CPM = 30.10; protein kinase, cAMP-dependent, catalytic, beta" ID="ID_938316956" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MED1: 1.03-fold Up; FDR = 0.911; PValue = 0.699; mean CPM = 81.93; mediator complex subunit 1" ID="ID_699795496" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RXRG: 1.32-fold Up; FDR = 0.915; PValue = 0.714; mean CPM = 0.8688; retinoid X receptor, gamma" ID="ID_1926080635" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG2: 1.06-fold Up; FDR = 0.985; PValue = 0.834; mean CPM = 2.248; phospholipase C, gamma 2 (phosphatidylinositol-specific)" ID="ID_715691051" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREBBP: 1.01-fold Down; FDR = 0.993; PValue = 0.847; mean CPM = 137.7; CREB binding protein" ID="ID_1600870554" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALB1: 1.07-fold Down; FDR = 0.994; PValue = 0.849; mean CPM = 1.025; calbindin 1, 28kDa" ID="ID_152743830" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC3: 1.01-fold Up; FDR = 1; PValue = 0.861; mean CPM = 41.13; histone deacetylase 3" ID="ID_470194702" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMARCE1: No Change; FDR = 1; PValue = 0.982; mean CPM = 71.75; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1" ID="ID_1029193418" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMARCD2: No Change; FDR = 1; PValue = 1; mean CPM = 35.43; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2" ID="ID_1351835867" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTH: No Change; FDR = 1; PValue = 1; mean CPM = 0.7843; parathyroid hormone" ID="ID_1275030349" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="RXR: FDR = 9.3e-05, PValue = 7.58e-05" ID="ID_788808089" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="NCOA2: 1.84-fold Up; FDR = 6.82e-14; PValue = 8.49e-16; mean CPM = 56.22; nuclear receptor coactivator 2" ID="ID_1518532266" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GTF2E1: 1.41-fold Up; FDR = 0.000355; PValue = 5.22e-05; mean CPM = 29.08; general transcription factor IIE, polypeptide 1, alpha 56kDa" ID="ID_59586044" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GTF2B: 1.3-fold Up; FDR = 0.0019; PValue = 0.000351; mean CPM = 38.87; general transcription factor IIB" ID="ID_326690494" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GTF2A1: 1.27-fold Up; FDR = 0.00826; PValue = 0.00188; mean CPM = 30.38; general transcription factor IIA, 1, 19/37kDa" ID="ID_1509525826" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCOA3: 1.24-fold Up; FDR = 0.0123; PValue = 0.00297; mean CPM = 178.3; nuclear receptor coactivator 3" ID="ID_1701332527" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GTF2F1: 1.32-fold Down; FDR = 0.0374; PValue = 0.0109; mean CPM = 8.075; general transcription factor IIF, polypeptide 1, 74kDa" ID="ID_266085167" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RXRA: 1.18-fold Down; FDR = 0.077; PValue = 0.0257; mean CPM = 35.60; retinoid X receptor, alpha" ID="ID_237999313" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCOA1: 1.18-fold Up; FDR = 0.112; PValue = 0.04; mean CPM = 20.42; nuclear receptor coactivator 1" ID="ID_1777468111" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="POLR2A: 1.12-fold Down; FDR = 0.365; PValue = 0.172; mean CPM = 296.4; polymerase (RNA) II (DNA directed) polypeptide A, 220kDa" ID="ID_1058740744" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBP: 1.12-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 14.69; TATA box binding protein" ID="ID_241722870" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KAT2B: 1.13-fold Up; FDR = 0.663; PValue = 0.378; mean CPM = 11.06; Uncharacterized protein" ID="ID_1117920789" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ERCC3: 1.05-fold Down; FDR = 0.746; PValue = 0.446; mean CPM = 82.81; Uncharacterized protein" ID="ID_171163373" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC3: 1.01-fold Up; FDR = 1; PValue = 0.861; mean CPM = 41.13; histone deacetylase 3" ID="ID_1322182576" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="SDF1 / CXCR4: FDR = 0.000102, PValue = 8.5e-05" ID="ID_784949118" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1393246226" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2B: 3.54-fold Up; FDR = 1.24e-07; PValue = 7.07e-09; mean CPM = 5.971; PTK2B protein tyrosine kinase 2 beta" ID="ID_794496797" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1016691216" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1302138809" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAI1: 1.47-fold Up; FDR = 5.94e-05; PValue = 6.9e-06; mean CPM = 97.19; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1" ID="ID_459291708" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCAR1: 1.36-fold Up; FDR = 0.000193; PValue = 2.61e-05; mean CPM = 210.4; breast cancer anti-estrogen resistance 1" ID="ID_1025091137" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCR4: 4.65-fold Down; FDR = 0.00226; PValue = 0.000426; mean CPM = 2.073; chemokine (C-X-C motif) receptor 4" ID="ID_848843082" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG1: 1.31-fold Down; FDR = 0.00352; PValue = 0.000707; mean CPM = 53.66; phospholipase C, gamma 1" ID="ID_1739632893" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1181604781" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_871713392" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_567638304" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2: 1.1-fold Up; FDR = 0.394; PValue = 0.191; mean CPM = 102.5; PTK2 protein tyrosine kinase 2" ID="ID_203994491" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_133106981" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL12: 1.27-fold Down; FDR = 0.488; PValue = 0.251; mean CPM = 4.383; chemokine (C-X-C motif) ligand 12" ID="ID_480581851" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNB1: 1.08-fold Down; FDR = 0.565; PValue = 0.305; mean CPM = 299.4; guanine nucleotide binding protein (G protein), beta polypeptide 1" ID="ID_981697774" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCB: 1.86-fold Up; FDR = 0.727; PValue = 0.43; mean CPM = 0.8705; protein kinase C, beta" ID="ID_1437955156" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRK: 1.05-fold Up; FDR = 0.791; PValue = 0.488; mean CPM = 59.92; v-crk sarcoma virus CT10 oncogene homolog (avian)" ID="ID_505907986" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAQ: 1.05-fold Down; FDR = 0.889; PValue = 0.611; mean CPM = 9.623; Guanine nucleotide-binding protein G(Q) subunit alpha; Uncharacterized protein" ID="ID_1923797239" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_1372717398" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNGT1: 1.05-fold Up; FDR = 1; PValue = 0.871; mean CPM = 0.8362; guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1" ID="ID_1074646299" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAQ: No Change; FDR = 1; PValue = 0.975; mean CPM = 15.20; guanine nucleotide binding protein (G protein), q polypeptide" ID="ID_899422121" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="MAPK: FDR = 0.000104, PValue = 8.89e-05" ID="ID_1547086004" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_707156192" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MRAS: 2.04-fold Up; FDR = 4.47e-15; PValue = 4.43e-17; mean CPM = 41.38; muscle RAS oncogene homolog" ID="ID_187723915" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB3: 4.82-fold Down; FDR = 1.82e-12; PValue = 3.09e-14; mean CPM = 9.911; transforming growth factor, beta 3" ID="ID_646629336" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SRF: 1.69-fold Down; FDR = 8.07e-11; PValue = 2.06e-12; mean CPM = 34.61; serum response factor (c-fos serum response element-binding transcription factor)" ID="ID_78211250" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA1B: 2.24-fold Down; FDR = 4.33e-09; PValue = 1.71e-10; mean CPM = 44.90; Heat shock 70 kDa protein 1A/1B (Heat shock 70 kDa protein 1/2)(HSP70.1/HSP70.2)(HSP70-1/HSP70-2)" ID="ID_117744783" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGFR: 1.84-fold Up; FDR = 6.71e-09; PValue = 2.77e-10; mean CPM = 68.58; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)" ID="ID_885560083" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGFR2: 3.45-fold Down; FDR = 1.04e-08; PValue = 4.53e-10; mean CPM = 5.064; fibroblast growth factor receptor 2" ID="ID_909629320" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA8: 1.64-fold Up; FDR = 1.46e-08; PValue = 6.6e-10; mean CPM = 1881; heat shock 70kDa protein 8" ID="ID_1540843246" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FLNA: 2.35-fold Down; FDR = 2.01e-08; PValue = 9.45e-10; mean CPM = 7159; filamin A, alpha" ID="ID_1141476068" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DUSP7: 1.77-fold Down; FDR = 3.08e-08; PValue = 1.52e-09; mean CPM = 22.67; dual specificity phosphatase 7" ID="ID_1863170878" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TAOK2: 1.59-fold Down; FDR = 9.28e-08; PValue = 5.13e-09; mean CPM = 76.85; TAO kinase 2" ID="ID_213632998" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1B: 1.55-fold Up; FDR = 2.39e-07; PValue = 1.46e-08; mean CPM = 135.3; Ras-related protein Rap-1b; Ras-related protein Rap-1b isoform 1; Uncharacterized protein" ID="ID_453088424" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K6: 2.05-fold Down; FDR = 2.49e-07; PValue = 1.53e-08; mean CPM = 17.57; Uncharacterized protein" ID="ID_141569596" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_1497107923" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD14: 2.75-fold Down; FDR = 6.54e-07; PValue = 4.46e-08; mean CPM = 5.195; CD14 molecule" ID="ID_1005507971" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DDIT3: 2.05-fold Up; FDR = 1.46e-06; PValue = 1.09e-07; mean CPM = 45.52; DNA-damage-inducible transcript 3" ID="ID_1281824249" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_522537343" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_961502523" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DUSP5: 1.66-fold Up; FDR = 2.33e-06; PValue = 1.84e-07; mean CPM = 66.43; dual specificity phosphatase 5" ID="ID_658682806" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGFR3: 3.85-fold Down; FDR = 2.66e-06; PValue = 2.13e-07; mean CPM = 2.800; fibroblast growth factor receptor 3" ID="ID_1268379924" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K3: 1.45-fold Down; FDR = 7.01e-06; PValue = 6.34e-07; mean CPM = 180.1; mitogen-activated protein kinase kinase 3" ID="ID_510876595" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MINK1: 1.41-fold Down; FDR = 9.48e-06; PValue = 8.88e-07; mean CPM = 87.29; misshapen-like kinase 1" ID="ID_1420862472" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8IP3: 1.77-fold Down; FDR = 1.28e-05; PValue = 1.24e-06; mean CPM = 65.23; mitogen-activated protein kinase 8 interacting protein 3" ID="ID_27743615" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA5: 3.28-fold Up; FDR = 1.4e-05; PValue = 1.36e-06; mean CPM = 2.288; ribosomal protein S6 kinase, 90kDa, polypeptide 5" ID="ID_839043734" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_468044181" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASGRF2: 5.55-fold Up; FDR = 2.4e-05; PValue = 2.48e-06; mean CPM = 2.163; Ras protein-specific guanine nucleotide-releasing factor 2" ID="ID_639352631" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP4K4: 1.4-fold Down; FDR = 3.08e-05; PValue = 3.27e-06; mean CPM = 242.8; mitogen-activated protein kinase kinase kinase kinase 4" ID="ID_906052108" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPT: 2.89-fold Down; FDR = 3.14e-05; PValue = 3.34e-06; mean CPM = 2.105; microtubule-associated protein tau" ID="ID_1192914021" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1R1: 1.6-fold Up; FDR = 3.35e-05; PValue = 3.61e-06; mean CPM = 123.7; interleukin 1 receptor, type I" ID="ID_1967255724" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K5: 1.55-fold Up; FDR = 7.6e-05; PValue = 9.12e-06; mean CPM = 16.82; mitogen-activated protein kinase kinase 5" ID="ID_358359360" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACA: 1.36-fold Down; FDR = 0.000167; PValue = 2.22e-05; mean CPM = 37.75; protein kinase, cAMP-dependent, catalytic, alpha" ID="ID_1517918748" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP2: 1.45-fold Up; FDR = 0.000179; PValue = 2.4e-05; mean CPM = 65.31; TGF-beta activated kinase 1/MAP3K7 binding protein 2" ID="ID_1254599065" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP3CA: 1.55-fold Up; FDR = 0.0003; PValue = 4.32e-05; mean CPM = 40.21; protein phosphatase 3, catalytic subunit, alpha isozyme" ID="ID_800889991" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF2: 1.34-fold Up; FDR = 0.000403; PValue = 6.01e-05; mean CPM = 39.83; activating transcription factor 2" ID="ID_1720749741" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_1964393212" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNA12: 1.32-fold Down; FDR = 0.000955; PValue = 0.00016; mean CPM = 33.75; Uncharacterized protein" ID="ID_1313483719" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPM1A: 1.31-fold Up; FDR = 0.00101; PValue = 0.00017; mean CPM = 60.08; protein phosphatase, Mg2+/Mn2+ dependent, 1A" ID="ID_1627298769" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCH: 1.98-fold Down; FDR = 0.00105; PValue = 0.000179; mean CPM = 3.182; protein kinase C, eta" ID="ID_1592733815" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NR4A1: 1.74-fold Down; FDR = 0.00108; PValue = 0.000184; mean CPM = 312.6; nuclear receptor subfamily 4, group A, member 1" ID="ID_662528648" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DUSP1: 1.39-fold Down; FDR = 0.00173; PValue = 0.000315; mean CPM = 355.2; dual specificity phosphatase 1" ID="ID_48384458" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPM1B: 1.36-fold Up; FDR = 0.00193; PValue = 0.000358; mean CPM = 16.96; protein phosphatase, Mg2+/Mn2+ dependent, 1B" ID="ID_1505543359" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NGF: 1.32-fold Up; FDR = 0.00212; PValue = 0.000396; mean CPM = 198.5; nerve growth factor (beta polypeptide)" ID="ID_1888871573" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF4: 1.29-fold Up; FDR = 0.00296; PValue = 0.000579; mean CPM = 618.7; activating transcription factor 4 (tax-responsive enhancer element B67)" ID="ID_1782293994" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DUSP10: 1.56-fold Down; FDR = 0.00343; PValue = 0.000687; mean CPM = 9.531; dual specificity phosphatase 10" ID="ID_287798361" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1B: 1.43-fold Up; FDR = 0.00346; PValue = 0.000693; mean CPM = 12.81; RAP1B, member of RAS oncogene family" ID="ID_621711010" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAX: 1.28-fold Up; FDR = 0.00569; PValue = 0.00123; mean CPM = 29.78; MYC associated factor X" ID="ID_1861930277" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_1745416832" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K14: 1.47-fold Down; FDR = 0.00704; PValue = 0.00157; mean CPM = 9.470; mitogen-activated protein kinase kinase kinase 14" ID="ID_948605506" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K3: 1.26-fold Down; FDR = 0.00786; PValue = 0.00178; mean CPM = 38.85; mitogen-activated protein kinase kinase kinase 3" ID="ID_1665364636" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K11: 1.24-fold Down; FDR = 0.0116; PValue = 0.00279; mean CPM = 45.82; mitogen-activated protein kinase kinase kinase 11" ID="ID_1891526710" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFB: 1.97-fold Down; FDR = 0.0133; PValue = 0.00326; mean CPM = 2.424; platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)" ID="ID_388998725" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCZ: 1.51-fold Up; FDR = 0.0152; PValue = 0.00381; mean CPM = 10.46; protein kinase C, zeta" ID="ID_1569219951" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BDNF: 1.23-fold Down; FDR = 0.0158; PValue = 0.00399; mean CPM = 104.4; Brain-derived neurotrophic factor" ID="ID_1110121008" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN5: 3.05-fold Down; FDR = 0.0177; PValue = 0.00455; mean CPM = 1.043; protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)" ID="ID_555979236" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_191215759" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1244781681" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_1682093280" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC2: 2.96-fold Up; FDR = 0.0309; PValue = 0.00872; mean CPM = 0.9737; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)" ID="ID_895735322" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GADD45A: 1.22-fold Up; FDR = 0.0344; PValue = 0.00989; mean CPM = 127.8; growth arrest and DNA-damage-inducible, alpha" ID="ID_54107602" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ECSIT: 1.2-fold Down; FDR = 0.0358; PValue = 0.0104; mean CPM = 54.27; ECSIT homolog (Drosophila)" ID="ID_622063516" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFBR1: 1.2-fold Up; FDR = 0.037; PValue = 0.0108; mean CPM = 90.92; transforming growth factor, beta receptor 1" ID="ID_1568220452" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1008807670" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KRAS: 1.35-fold Down; FDR = 0.0401; PValue = 0.0119; mean CPM = 13.10; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog" ID="ID_193975805" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NRAS: 1.2-fold Down; FDR = 0.0546; PValue = 0.017; mean CPM = 32.39; neuroblastoma RAS viral (v-ras) oncogene homolog" ID="ID_1002705200" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPRR: 1.72-fold Down; FDR = 0.0559; PValue = 0.0175; mean CPM = 7.682; protein tyrosine phosphatase, receptor type, R" ID="ID_1276970608" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFBR2: 1.19-fold Up; FDR = 0.0643; PValue = 0.0208; mean CPM = 350.8; transforming growth factor, beta receptor II (70/80kDa)" ID="ID_679173277" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_627228637" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MKNK1: 1.27-fold Down; FDR = 0.0706; PValue = 0.0232; mean CPM = 9.169; MAP kinase interacting serine/threonine kinase 1" ID="ID_505008506" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TAOK1: 1.17-fold Up; FDR = 0.0749; PValue = 0.0249; mean CPM = 101.1; TAO kinase 1" ID="ID_364382362" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K8: 1.35-fold Down; FDR = 0.0831; PValue = 0.0281; mean CPM = 8.912; mitogen-activated protein kinase kinase kinase 8" ID="ID_264955088" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1A: 1.17-fold Up; FDR = 0.0888; PValue = 0.0304; mean CPM = 37.16; RAP1A, member of RAS oncogene family" ID="ID_834956420" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS2: 1.17-fold Up; FDR = 0.1; PValue = 0.0353; mean CPM = 31.79; son of sevenless homolog 2 (Drosophila)" ID="ID_41340488" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARRB1: 1.35-fold Down; FDR = 0.107; PValue = 0.0382; mean CPM = 4.106; arrestin, beta 1" ID="ID_1417474921" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_831685754" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MKNK2: 1.23-fold Up; FDR = 0.123; PValue = 0.0449; mean CPM = 81.36; MAP kinase interacting serine/threonine kinase 2" ID="ID_732359636" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_1070162068" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DUSP6: 1.22-fold Up; FDR = 0.131; PValue = 0.0487; mean CPM = 91.01; dual specificity phosphatase 6" ID="ID_1528309125" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK2: 1.15-fold Up; FDR = 0.134; PValue = 0.0502; mean CPM = 89.49; p21 protein (Cdc42/Rac)-activated kinase 2" ID="ID_595522401" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGFR1: 1.15-fold Down; FDR = 0.139; PValue = 0.0525; mean CPM = 89.41; fibroblast growth factor receptor 1" ID="ID_1073827608" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1774586772" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD1: 1.23-fold Down; FDR = 0.154; PValue = 0.0592; mean CPM = 31.65; frizzled homolog 1 (Drosophila)" ID="ID_547111089" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP6: 1.17-fold Up; FDR = 0.197; PValue = 0.0807; mean CPM = 14.25; caspase 6, apoptosis-related cysteine peptidase" ID="ID_1122641804" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_983524668" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DUSP4: 1.28-fold Down; FDR = 0.199; PValue = 0.0817; mean CPM = 66.70; dual specificity phosphatase 4" ID="ID_641086924" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP7: 1.15-fold Up; FDR = 0.218; PValue = 0.0916; mean CPM = 21.49; caspase 7, apoptosis-related cysteine peptidase" ID="ID_497085462" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASGRP1: 1.4-fold Down; FDR = 0.224; PValue = 0.0945; mean CPM = 2.348; RAS guanyl releasing protein 1 (calcium and DAG-regulated)" ID="ID_1100773361" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BRAF: 1.14-fold Down; FDR = 0.228; PValue = 0.0964; mean CPM = 24.98; v-raf murine sarcoma viral oncogene homolog B1" ID="ID_1744615322" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_1480452803" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K4: 1.13-fold Down; FDR = 0.284; PValue = 0.126; mean CPM = 25.34; Uncharacterized protein" ID="ID_1865074490" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA4: 1.12-fold Down; FDR = 0.296; PValue = 0.133; mean CPM = 39.50; ribosomal protein S6 kinase, 90kDa, polypeptide 4" ID="ID_1837283133" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPKAPK5: 1.15-fold Down; FDR = 0.297; PValue = 0.134; mean CPM = 13.06; mitogen-activated protein kinase-activated protein kinase 5" ID="ID_335263338" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1A: 1.5-fold Up; FDR = 0.315; PValue = 0.144; mean CPM = 155.4; interleukin 1, alpha" ID="ID_423167628" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP1: 1.12-fold Down; FDR = 0.351; PValue = 0.165; mean CPM = 17.96; TGF-beta activated kinase 1/MAP3K7 binding protein 1" ID="ID_343135540" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MEF2C: 1.24-fold Down; FDR = 0.357; PValue = 0.168; mean CPM = 6.816; myocyte enhancer factor 2C" ID="ID_1373611522" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP53: 1.11-fold Down; FDR = 0.364; PValue = 0.172; mean CPM = 33.25; tumor protein p53" ID="ID_983843855" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRKL: 1.11-fold Up; FDR = 0.371; PValue = 0.176; mean CPM = 34.10; v-crk sarcoma virus CT10 oncogene homolog (avian)-like" ID="ID_1060700231" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NF1: 1.1-fold Up; FDR = 0.383; PValue = 0.184; mean CPM = 199.1; neurofibromin 1" ID="ID_574849540" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK6: 1.34-fold Up; FDR = 0.407; PValue = 0.198; mean CPM = 2.043; mitogen-activated protein kinase 6" ID="ID_596448780" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1362324221" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK12: 1.19-fold Down; FDR = 0.422; PValue = 0.208; mean CPM = 6.569; mitogen-activated protein kinase 12" ID="ID_903715520" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_389768077" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC1: 1.11-fold Down; FDR = 0.457; PValue = 0.23; mean CPM = 19.06; Uncharacterized protein" ID="ID_1300410577" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP3CB: 1.08-fold Up; FDR = 0.514; PValue = 0.268; mean CPM = 76.44; protein phosphatase 3, catalytic subunit, beta isozyme" ID="ID_1367658543" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK13: 1.22-fold Down; FDR = 0.536; PValue = 0.284; mean CPM = 3.100; mitogen-activated protein kinase 13" ID="ID_1661301510" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACVR1C: 1.28-fold Down; FDR = 0.559; PValue = 0.3; mean CPM = 1.935; activin A receptor, type IC" ID="ID_1789973694" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K5: 1.21-fold Down; FDR = 0.6; PValue = 0.33; mean CPM = 8.023; mitogen-activated protein kinase kinase kinase 5" ID="ID_1062196788" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDC42: 1.07-fold Down; FDR = 0.608; PValue = 0.335; mean CPM = 91.67; cell division cycle 42" ID="ID_1119028485" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCG: 1.47-fold Down; FDR = 0.609; PValue = 0.336; mean CPM = 0.9297; protein kinase C, gamma" ID="ID_1858211662" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1R2: 1.37-fold Up; FDR = 0.628; PValue = 0.35; mean CPM = 1.132; interleukin 1 receptor, type II" ID="ID_1987696338" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_664881827" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STMN1: 1.15-fold Down; FDR = 0.684; PValue = 0.395; mean CPM = 43.13; Stathmin" ID="ID_1441740216" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCD: 1.06-fold Up; FDR = 0.696; PValue = 0.404; mean CPM = 37.45; protein kinase C, delta" ID="ID_851806733" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCB: 1.86-fold Up; FDR = 0.727; PValue = 0.43; mean CPM = 0.8705; protein kinase C, beta" ID="ID_424666850" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPKAPK2: 1.06-fold Down; FDR = 0.733; PValue = 0.435; mean CPM = 82.16; mitogen-activated protein kinase-activated protein kinase 2" ID="ID_970625754" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_574586878" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZAK: 1.05-fold Down; FDR = 0.789; PValue = 0.486; mean CPM = 32.04; Mitogen-activated protein kinase kinase kinase MLT isoform 2; Uncharacterized protein" ID="ID_267026523" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRK: 1.05-fold Up; FDR = 0.791; PValue = 0.488; mean CPM = 59.92; v-crk sarcoma virus CT10 oncogene homolog (avian)" ID="ID_1508118615" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP5C: 1.05-fold Up; FDR = 0.826; PValue = 0.526; mean CPM = 49.97; protein phosphatase 5, catalytic subunit" ID="ID_1589364714" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN7: 1.29-fold Up; FDR = 0.851; PValue = 0.562; mean CPM = 0.8740; protein tyrosine phosphatase, non-receptor type 7" ID="ID_613375155" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA5: 1.05-fold Up; FDR = 0.851; PValue = 0.562; mean CPM = 1754; heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)" ID="ID_554085397" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_572864838" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP4K1: 1.26-fold Up; FDR = 0.879; PValue = 0.598; mean CPM = 0.9281; mitogen-activated protein kinase kinase kinase kinase 1" ID="ID_1118816402" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_162011839" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK7: 1.04-fold Down; FDR = 0.899; PValue = 0.632; mean CPM = 16.93; Uncharacterized protein" ID="ID_347738341" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMEM37: 1.49-fold Down; FDR = 0.9; PValue = 0.636; mean CPM = 0.8533; transmembrane protein 37" ID="ID_57605776" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB2: 1.05-fold Down; FDR = 0.903; PValue = 0.655; mean CPM = 110.8; transforming growth factor, beta 2" ID="ID_1183092577" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP2: 1.05-fold Up; FDR = 0.906; PValue = 0.667; mean CPM = 12.88; caspase 2, apoptosis-related cysteine peptidase" ID="ID_1852453811" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLA2G10: 1.15-fold Up; FDR = 0.907; PValue = 0.675; mean CPM = 1.118; phospholipase A2, group X" ID="ID_1689328542" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASA1: 1.03-fold Down; FDR = 0.909; PValue = 0.69; mean CPM = 103.7; Ras GTPase-activating protein 1 isoform 1; Uncharacterized protein" ID="ID_1942699477" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NTF4: 1.14-fold Up; FDR = 0.911; PValue = 0.701; mean CPM = 0.7902; neurotrophin 4" ID="ID_613289705" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK1: 1.03-fold Down; FDR = 0.911; PValue = 0.705; mean CPM = 18.65; p21 protein (Cdc42/Rac)-activated kinase 1" ID="ID_205065265" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K2: 1.03-fold Up; FDR = 0.924; PValue = 0.73; mean CPM = 40.64; mitogen-activated protein kinase kinase kinase 2" ID="ID_1942074712" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP4K3: 1.03-fold Down; FDR = 0.926; PValue = 0.732; mean CPM = 18.57; mitogen-activated protein kinase kinase kinase kinase 3" ID="ID_647096266" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB1: 1.02-fold Down; FDR = 0.936; PValue = 0.749; mean CPM = 62.61; transforming growth factor, beta 1" ID="ID_1342923033" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FASLG: 1.2-fold Down; FDR = 0.941; PValue = 0.757; mean CPM = 0.8088; Fas ligand (TNF superfamily, member 6)" ID="ID_941065862" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_770854677" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC3: 1.03-fold Down; FDR = 0.952; PValue = 0.78; mean CPM = 13.31; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3" ID="ID_382908373" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MOS: 1.02-fold Up; FDR = 0.958; PValue = 0.791; mean CPM = 0.8131; v-mos Moloney murine sarcoma viral oncogene homolog" ID="ID_1623097707" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K13: 1.03-fold Up; FDR = 0.962; PValue = 0.796; mean CPM = 6.973; mitogen-activated protein kinase kinase kinase 13" ID="ID_904049902" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_495961848" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_100002517" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NTRK1: 1.07-fold Up; FDR = 0.977; PValue = 0.82; mean CPM = 1.195; neurotrophic tyrosine kinase, receptor, type 1" ID="ID_568958129" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GCK: 1.05-fold Up; FDR = 0.98; PValue = 0.824; mean CPM = 1.691; glucokinase (hexokinase 4)" ID="ID_347506972" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA3: 1.02-fold Up; FDR = 0.982; PValue = 0.829; mean CPM = 58.16; ribosomal protein S6 kinase, 90kDa, polypeptide 3" ID="ID_35408883" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_1330549259" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFRB: 1.01-fold Up; FDR = 1; PValue = 0.883; mean CPM = 391.1; platelet-derived growth factor receptor, beta polypeptide" ID="ID_182417268" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGF: 1.06-fold Down; FDR = 1; PValue = 0.885; mean CPM = 0.8917; epidermal growth factor" ID="ID_1767402576" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPB2: 1.05-fold Down; FDR = 1; PValue = 0.889; mean CPM = 0.9668; heat shock 27kDa protein 2" ID="ID_1817756838" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP9: 1.01-fold Up; FDR = 1; PValue = 0.908; mean CPM = 19.86; caspase 9, apoptosis-related cysteine peptidase" ID="ID_857925753" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK4: 1.19-fold Down; FDR = 1; PValue = 0.95; mean CPM = 0.8611; mitogen-activated protein kinase 4" ID="ID_1726942058" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLK: No Change; FDR = 1; PValue = 0.97; mean CPM = 11.78; nemo-like kinase" ID="ID_1443870886" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DAXX: No Change; FDR = 1; PValue = 0.984; mean CPM = 106.5; Death domain-associated protein 6 (Daxx)(hDaxx)(Fas death domain-associated protein)(ETS1-associated protein 1)(EAP1)" ID="ID_1076449972" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACVR1B: No Change; FDR = 1; PValue = 0.999; mean CPM = 11.63; activin A receptor, type IB" ID="ID_486283951" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SH2D1A: No Change; FDR = 1; PValue = 1; mean CPM = 0.7843; SH2 domain containing 1A" ID="ID_1347481313" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="B-cell receptor signaling pathway: FDR = 0.000158, PValue = 0.000138" ID="ID_1274137679" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="RASGRP3: 7.1-fold Up; FDR = 6.93e-13; PValue = 1.1e-14; mean CPM = 7.525; RAS guanyl releasing protein 3 (calcium and DAG-regulated)" ID="ID_1988079576" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_1483629949" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MEF2D: 1.73-fold Down; FDR = 2.02e-08; PValue = 9.5e-10; mean CPM = 61.43; myocyte enhancer factor 2D" ID="ID_1534653968" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_456699627" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1387932481" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1723532654" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL10: 1.55-fold Up; FDR = 5.92e-06; PValue = 5.22e-07; mean CPM = 21.83; B-cell CLL/lymphoma 10" ID="ID_254940184" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_428345005" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPRC: 6.08-fold Up; FDR = 0.000285; PValue = 4.07e-05; mean CPM = 1.220; protein tyrosine phosphatase, receptor type, C" ID="ID_1360976906" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC2: 4.03-fold Down; FDR = 0.000346; PValue = 5.06e-05; mean CPM = 1.347; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2" ID="ID_1279578545" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF2: 1.34-fold Up; FDR = 0.000403; PValue = 6.01e-05; mean CPM = 39.83; activating transcription factor 2" ID="ID_450884760" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCK1: 1.39-fold Up; FDR = 0.000442; PValue = 6.67e-05; mean CPM = 21.55; NCK adaptor protein 1" ID="ID_1233580880" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GTF2I: 1.31-fold Down; FDR = 0.000872; PValue = 0.000144; mean CPM = 94.25; general transcription factor IIi" ID="ID_882338383" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOXO1: 1.49-fold Down; FDR = 0.00109; PValue = 0.000186; mean CPM = 11.95; forkhead box O1" ID="ID_478062281" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KLF11: 1.5-fold Up; FDR = 0.0012; PValue = 0.000207; mean CPM = 20.77; Kruppel-like factor 11" ID="ID_1625953858" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAMK2A: 2.29-fold Down; FDR = 0.00124; PValue = 0.000217; mean CPM = 2.001; calcium/calmodulin-dependent protein kinase II alpha" ID="ID_1896784635" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GAB2: 1.33-fold Down; FDR = 0.00208; PValue = 0.000387; mean CPM = 22.59; GRB2-associated binding protein 2" ID="ID_282761644" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="REL: 1.46-fold Down; FDR = 0.00272; PValue = 0.000526; mean CPM = 10.17; v-rel avian reticuloendotheliosis viral oncogene homolog" ID="ID_1485423941" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG1: 1.31-fold Down; FDR = 0.00352; PValue = 0.000707; mean CPM = 53.66; phospholipase C, gamma 1" ID="ID_563846692" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIP5K1C: 1.27-fold Down; FDR = 0.00491; PValue = 0.00104; mean CPM = 37.75; phosphatidylinositol-4-phosphate 5-kinase, type I, gamma" ID="ID_740526453" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAT2: 2.71-fold Down; FDR = 0.00513; PValue = 0.00109; mean CPM = 2.049; linker for activation of T cells family, member 2" ID="ID_404911761" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1874484503" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAX: 1.28-fold Up; FDR = 0.00569; PValue = 0.00123; mean CPM = 29.78; MYC associated factor X" ID="ID_1601254160" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ILF2: 1.24-fold Down; FDR = 0.00962; PValue = 0.00225; mean CPM = 87.09; interleukin enhancer binding factor 2, 45kDa" ID="ID_479778706" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BLNK: 2.61-fold Up; FDR = 0.012; PValue = 0.00288; mean CPM = 1.254; Uncharacterized protein" ID="ID_294744929" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FYN: 1.22-fold Up; FDR = 0.0156; PValue = 0.00393; mean CPM = 92.94; FYN oncogene related to SRC, FGR, YES" ID="ID_42992137" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_522373478" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CARD11: 1.31-fold Down; FDR = 0.0223; PValue = 0.00597; mean CPM = 58.32; caspase recruitment domain family, member 11" ID="ID_1422641552" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA1: 1.25-fold Down; FDR = 0.0241; PValue = 0.00652; mean CPM = 21.28; ribosomal protein S6 kinase, 90kDa, polypeptide 1" ID="ID_822099848" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1088003602" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INPP5D: 1.88-fold Down; FDR = 0.0276; PValue = 0.00763; mean CPM = 5.690; inositol polyphosphate-5-phosphatase, 145kDa" ID="ID_708462168" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC2: 2.96-fold Up; FDR = 0.0309; PValue = 0.00872; mean CPM = 0.9737; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)" ID="ID_866620797" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB1: 1.21-fold Up; FDR = 0.0313; PValue = 0.00884; mean CPM = 36.07; cAMP responsive element binding protein 1" ID="ID_1687922506" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDPK1: 1.24-fold Down; FDR = 0.0361; PValue = 0.0105; mean CPM = 17.53; 3-phosphoinositide dependent protein kinase-1" ID="ID_1750111621" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_507507721" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DAG1: 1.54-fold Down; FDR = 0.0661; PValue = 0.0214; mean CPM = 3.013; dystroglycan 1 (dystrophin-associated glycoprotein 1)" ID="ID_1053170415" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_416173517" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_1134050871" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TEC: 1.65-fold Up; FDR = 0.0729; PValue = 0.0241; mean CPM = 3.190; tec protein tyrosine kinase" ID="ID_1743573424" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3A: 1.18-fold Down; FDR = 0.097; PValue = 0.0338; mean CPM = 25.14; Glycogen synthase kinase-3 alpha; Uncharacterized protein" ID="ID_1141627277" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ETS1: 1.16-fold Up; FDR = 0.0996; PValue = 0.0348; mean CPM = 94.27; v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)" ID="ID_1339909559" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3AP1: 2.18-fold Up; FDR = 0.108; PValue = 0.0384; mean CPM = 1.085; phosphoinositide-3-kinase adaptor protein 1" ID="ID_1600770614" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_991253015" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF4: 2.95-fold Down; FDR = 0.124; PValue = 0.0456; mean CPM = 0.9773; interferon regulatory factor 4" ID="ID_927480434" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_542486350" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_942813255" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1922809785" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_729550380" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_1845706560" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BRAF: 1.14-fold Down; FDR = 0.228; PValue = 0.0964; mean CPM = 24.98; v-raf murine sarcoma viral oncogene homolog B1" ID="ID_1340617796" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_1865684230" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MALT1: 1.11-fold Down; FDR = 0.35; PValue = 0.164; mean CPM = 42.89; mucosa associated lymphoid tissue lymphoma translocation gene 1" ID="ID_117369089" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MEF2C: 1.24-fold Down; FDR = 0.357; PValue = 0.168; mean CPM = 6.816; myocyte enhancer factor 2C" ID="ID_682561241" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRKL: 1.11-fold Up; FDR = 0.371; PValue = 0.176; mean CPM = 34.10; v-crk sarcoma virus CT10 oncogene homolog (avian)-like" ID="ID_1422684819" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_319213115" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1659153750" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_841227992" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDC42: 1.07-fold Down; FDR = 0.608; PValue = 0.335; mean CPM = 91.67; cell division cycle 42" ID="ID_1894876786" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GAB1: 1.1-fold Up; FDR = 0.635; PValue = 0.356; mean CPM = 14.59; GRB2-associated binding protein 1" ID="ID_692781583" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMD4: 1.07-fold Up; FDR = 0.662; PValue = 0.377; mean CPM = 196.2; Macaca mulatta proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 (PSMD4), mRNA." ID="ID_1959481072" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCD: 1.06-fold Up; FDR = 0.696; PValue = 0.404; mean CPM = 37.45; protein kinase C, delta" ID="ID_548062778" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCB: 1.86-fold Up; FDR = 0.727; PValue = 0.43; mean CPM = 0.8705; protein kinase C, beta" ID="ID_703125149" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HCLS1: 1.11-fold Up; FDR = 0.749; PValue = 0.449; mean CPM = 12.24; Hematopoietic lineage cell-specific protein; Uncharacterized protein" ID="ID_431554600" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="E2F3: 1.08-fold Up; FDR = 0.751; PValue = 0.452; mean CPM = 11.79; E2F transcription factor 3" ID="ID_1454722864" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAPGEF1: 1.05-fold Down; FDR = 0.763; PValue = 0.462; mean CPM = 70.38; Rap guanine nucleotide exchange factor (GEF) 1" ID="ID_779506867" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRK: 1.05-fold Up; FDR = 0.791; PValue = 0.488; mean CPM = 59.92; v-crk sarcoma virus CT10 oncogene homolog (avian)" ID="ID_1789395084" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN18: 1.06-fold Down; FDR = 0.809; PValue = 0.506; mean CPM = 17.07; protein tyrosine phosphatase, non-receptor type 18 (brain-derived)" ID="ID_1051413714" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CBL: 1.05-fold Down; FDR = 0.824; PValue = 0.524; mean CPM = 51.06; Cas-Br-M (murine) ecotropic retroviral transforming sequence" ID="ID_959821065" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL6: 1.06-fold Down; FDR = 0.837; PValue = 0.542; mean CPM = 64.49; B-cell CLL/lymphoma 6" ID="ID_62505457" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD79A: 1.84-fold Down; FDR = 0.847; PValue = 0.556; mean CPM = 0.8487; CD79a molecule, immunoglobulin-associated alpha" ID="ID_1508843494" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_641989929" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV1: 1.25-fold Down; FDR = 0.858; PValue = 0.572; mean CPM = 0.9515; vav 1 guanine nucleotide exchange factor" ID="ID_805773316" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1340510576" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP4K1: 1.26-fold Up; FDR = 0.879; PValue = 0.598; mean CPM = 0.9281; mitogen-activated protein kinase kinase kinase kinase 1" ID="ID_868068948" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_467578756" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC3: 1.03-fold Down; FDR = 0.952; PValue = 0.78; mean CPM = 13.31; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3" ID="ID_175753564" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_1289738748" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_792481392" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG2: 1.06-fold Up; FDR = 0.985; PValue = 0.834; mean CPM = 2.248; phospholipase C, gamma 2 (phosphatidylinositol-specific)" ID="ID_201941119" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD19: 1.15-fold Up; FDR = 1; PValue = 0.922; mean CPM = 0.8554; CD19 molecule" ID="ID_84227401" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD22: 1.18-fold Down; FDR = 1; PValue = 0.928; mean CPM = 0.8572; CD22 molecule" ID="ID_1679559365" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK4: 1.19-fold Down; FDR = 1; PValue = 0.95; mean CPM = 0.8611; mitogen-activated protein kinase 4" ID="ID_1697321948" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BTK: No Change; FDR = 1; PValue = 0.965; mean CPM = 0.8336; Bruton agammaglobulinemia tyrosine kinase" ID="ID_1121011364" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV2: No Change; FDR = 1; PValue = 0.976; mean CPM = 25.65; vav 2 guanine nucleotide exchange factor" ID="ID_1242855002" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SYK: 1.11-fold Up; FDR = 1; PValue = 0.977; mean CPM = 0.8420; spleen tyrosine kinase" ID="ID_612345880" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CR2: 1.07-fold Down; FDR = 1; PValue = 0.997; mean CPM = 0.8253; complement component (3d/Epstein Barr virus) receptor 2" ID="ID_1259010672" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD79B: No Change; FDR = 1; PValue = 1; mean CPM = 0.7830; CD79b molecule, immunoglobulin-associated beta" ID="ID_1536786102" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="WNT signaling: FDR = 0.000219, PValue = 0.000194" ID="ID_1869612283" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="NFATC4: 1.85-fold Down; FDR = 1.13e-11; PValue = 2.37e-13; mean CPM = 51.58; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4" ID="ID_669309376" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD2: 2.27-fold Down; FDR = 5e-11; PValue = 1.24e-12; mean CPM = 20.66; frizzled homolog 2 (Drosophila)" ID="ID_1526985369" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND3: 2.27-fold Down; FDR = 8.38e-11; PValue = 2.15e-12; mean CPM = 86.90; cyclin D3" ID="ID_160845079" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRICKLE2: 2.93-fold Down; FDR = 3.36e-09; PValue = 1.3e-10; mean CPM = 14.29; prickle homolog 2 (Drosophila)" ID="ID_1818707192" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAMK2D: 1.54-fold Up; FDR = 4.06e-08; PValue = 2.07e-09; mean CPM = 51.52; calcium/calmodulin-dependent protein kinase II delta" ID="ID_803694730" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPARD: 1.76-fold Down; FDR = 1.58e-07; PValue = 9.27e-09; mean CPM = 32.10; peroxisome proliferator-activated receptor delta" ID="ID_1263633633" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCB1: 1.71-fold Up; FDR = 1.31e-06; PValue = 9.73e-08; mean CPM = 34.36; phospholipase C, beta 1 (phosphoinositide-specific)" ID="ID_1996764118" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_357125131" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC3: 1.68-fold Down; FDR = 2.72e-06; PValue = 2.19e-07; mean CPM = 13.98; ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)" ID="ID_1729658199" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD7: 1.62-fold Down; FDR = 5.66e-06; PValue = 4.95e-07; mean CPM = 34.19; frizzled homolog 7 (Drosophila)" ID="ID_1889872629" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTNNBIP1: 1.62-fold Down; FDR = 6.5e-06; PValue = 5.82e-07; mean CPM = 12.40; catenin, beta interacting protein 1" ID="ID_1962997639" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DKK1: 1.73-fold Up; FDR = 8.46e-06; PValue = 7.83e-07; mean CPM = 206.3; dickkopf homolog 1 (Xenopus laevis)" ID="ID_1363111306" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT5A: 1.65-fold Down; FDR = 2.5e-05; PValue = 2.59e-06; mean CPM = 136.4; wingless-type MMTV integration site family, member 5A" ID="ID_1618601497" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R1B: 1.39-fold Down; FDR = 4.37e-05; PValue = 4.86e-06; mean CPM = 233.1; protein phosphatase 2, regulatory subunit A, beta" ID="ID_761675743" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000009315: 1.44-fold Down; FDR = 4.44e-05; PValue = 4.94e-06; mean CPM = 22.79" ID="ID_840231834" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AXIN2: 3.75-fold Down; FDR = 6.09e-05; PValue = 7.1e-06; mean CPM = 2.690; axin 2" ID="ID_1908415786" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRICKLE1: 1.61-fold Up; FDR = 7.19e-05; PValue = 8.57e-06; mean CPM = 16.83; prickle homolog 1 (Drosophila)" ID="ID_718340361" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R5A: 1.45-fold Up; FDR = 0.000141; PValue = 1.83e-05; mean CPM = 21.64; protein phosphatase 2, regulatory subunit B', alpha" ID="ID_1245247924" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACA: 1.36-fold Down; FDR = 0.000167; PValue = 2.22e-05; mean CPM = 37.75; protein kinase, cAMP-dependent, catalytic, alpha" ID="ID_1443410628" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2CB: 1.35-fold Up; FDR = 0.000215; PValue = 2.96e-05; mean CPM = 59.68; protein phosphatase 2, catalytic subunit, beta isozyme" ID="ID_876744759" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCB4: 1.75-fold Down; FDR = 0.00025; PValue = 3.52e-05; mean CPM = 6.730; phospholipase C, beta 4" ID="ID_472411492" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LRP5: 1.49-fold Down; FDR = 0.000262; PValue = 3.71e-05; mean CPM = 198.7; Uncharacterized protein" ID="ID_1699253147" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP3CA: 1.55-fold Up; FDR = 0.0003; PValue = 4.32e-05; mean CPM = 40.21; protein phosphatase 3, catalytic subunit, alpha isozyme" ID="ID_205699397" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC2: 4.03-fold Down; FDR = 0.000346; PValue = 5.06e-05; mean CPM = 1.347; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2" ID="ID_414750649" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD9: 2.74-fold Down; FDR = 0.000408; PValue = 6.1e-05; mean CPM = 1.789; frizzled homolog 9 (Drosophila)" ID="ID_1485643387" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBL1Y: 1.41-fold Up; FDR = 0.000492; PValue = 7.5e-05; mean CPM = 32.35; F-box-like/WD repeat-containing protein TBL1Y" ID="ID_364040518" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD3: 1.38-fold Up; FDR = 0.000573; PValue = 8.94e-05; mean CPM = 114.9; SMAD family member 3" ID="ID_1472021026" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT1: 7.1-fold Down; FDR = 0.000659; PValue = 0.000105; mean CPM = 2.664; wingless-type MMTV integration site family, member 1" ID="ID_305172970" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAMK2A: 2.29-fold Down; FDR = 0.00124; PValue = 0.000217; mean CPM = 2.001; calcium/calmodulin-dependent protein kinase II alpha" ID="ID_1055943237" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RUVBL1: 1.33-fold Up; FDR = 0.00132; PValue = 0.000232; mean CPM = 57.28; RuvB-like 1 (E. coli)" ID="ID_1465381723" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DVL3: 1.29-fold Down; FDR = 0.00157; PValue = 0.00028; mean CPM = 67.95; dishevelled, dsh homolog 3 (Drosophila)" ID="ID_1884266160" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PORCN: 1.5-fold Down; FDR = 0.00213; PValue = 0.000399; mean CPM = 7.981; porcupine homolog (Drosophila)" ID="ID_88300766" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD4: 1.83-fold Up; FDR = 0.00258; PValue = 0.000495; mean CPM = 4.537; frizzled homolog 4 (Drosophila)" ID="ID_525752795" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHOA: 1.28-fold Down; FDR = 0.00295; PValue = 0.000575; mean CPM = 277.8; ras homolog gene family, member A" ID="ID_612867173" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKX: 1.31-fold Down; FDR = 0.00331; PValue = 0.000658; mean CPM = 24.94; protein kinase, X-linked" ID="ID_1996141719" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R5D: 1.27-fold Down; FDR = 0.00482; PValue = 0.00101; mean CPM = 35.61; protein phosphatase 2, regulatory subunit B', delta" ID="ID_1866187675" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VANGL1: 1.33-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 16.07; VANGL planar cell polarity protein 1" ID="ID_1651746849" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAMK2B: 3.82-fold Down; FDR = 0.00536; PValue = 0.00115; mean CPM = 1.542; calcium/calmodulin-dependent protein kinase II beta" ID="ID_114512366" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_57925773" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT7A: 3.46-fold Down; FDR = 0.00638; PValue = 0.0014; mean CPM = 1.036; wingless-type MMTV integration site family, member 7A" ID="ID_1187197546" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT10A: 4.08-fold Down; FDR = 0.00805; PValue = 0.00183; mean CPM = 0.9138; wingless-type MMTV integration site family, member 10A" ID="ID_506134873" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DAAM2: 1.27-fold Down; FDR = 0.00807; PValue = 0.00184; mean CPM = 130.1; dishevelled associated activator of morphogenesis 2" ID="ID_1049067532" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT5B: 1.58-fold Down; FDR = 0.00866; PValue = 0.002; mean CPM = 7.832; wingless-type MMTV integration site family, member 5B" ID="ID_1563282469" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SIAH1: 1.32-fold Up; FDR = 0.0104; PValue = 0.00245; mean CPM = 14.33; seven in absentia homolog 1 (Drosophila)" ID="ID_1338774493" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CUL1: 1.24-fold Up; FDR = 0.0104; PValue = 0.00247; mean CPM = 106.1; cullin 1" ID="ID_400778998" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTBP1: 1.23-fold Down; FDR = 0.0119; PValue = 0.00287; mean CPM = 100.6; C-terminal binding protein 1" ID="ID_1554849339" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSNK2A2: 1.28-fold Up; FDR = 0.0129; PValue = 0.00314; mean CPM = 19.86; casein kinase 2, alpha prime polypeptide" ID="ID_779482804" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SFRP2: 1.53-fold Down; FDR = 0.0136; PValue = 0.00334; mean CPM = 373.9; secreted frizzled-related protein 2" ID="ID_1095141674" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT10B: 3.1-fold Down; FDR = 0.0148; PValue = 0.00369; mean CPM = 1.086; wingless-type MMTV integration site family, member 10B" ID="ID_791333324" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTBP2: 1.23-fold Up; FDR = 0.0166; PValue = 0.00423; mean CPM = 49.75; C-terminal binding protein 2" ID="ID_1509469402" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AC012652.1: 1.23-fold Down; FDR = 0.0201; PValue = 0.0053; mean CPM = 33.80; Calcium-binding protein p22 (Calcium-binding protein CHP)(Calcineurin homologous protein)(Calcineurin B homolog)" ID="ID_545002610" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFAT5: 1.21-fold Up; FDR = 0.0273; PValue = 0.00754; mean CPM = 113.0; nuclear factor of activated T-cells 5, tonicity-responsive" ID="ID_1097965336" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC2: 2.96-fold Up; FDR = 0.0309; PValue = 0.00872; mean CPM = 0.9737; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)" ID="ID_515369781" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD2: 1.2-fold Up; FDR = 0.034; PValue = 0.00976; mean CPM = 57.10; SMAD family member 2" ID="ID_1545009003" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TCF7: 1.72-fold Down; FDR = 0.0376; PValue = 0.011; mean CPM = 4.279; transcription factor 7 (T-cell specific, HMG-box)" ID="ID_765768480" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACYBP: 1.2-fold Up; FDR = 0.0455; PValue = 0.0138; mean CPM = 51.35; Calcyclin-binding protein isoform 1; Uncharacterized protein" ID="ID_1673439209" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCB2: 3.68-fold Down; FDR = 0.0481; PValue = 0.0147; mean CPM = 1.557; Uncharacterized protein" ID="ID_1584028234" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTNNB1: 1.2-fold Up; FDR = 0.0498; PValue = 0.0153; mean CPM = 558.3; catenin (cadherin-associated protein), beta 1, 88kDa" ID="ID_894832070" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APC2: 1.29-fold Down; FDR = 0.0505; PValue = 0.0155; mean CPM = 8.899; adenomatosis polyposis coli 2" ID="ID_1651916893" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT4: 1.52-fold Down; FDR = 0.0525; PValue = 0.0163; mean CPM = 13.66; wingless-type MMTV integration site family, member 4" ID="ID_966485211" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_1786833981" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TCF7L1: 1.2-fold Down; FDR = 0.0783; PValue = 0.0262; mean CPM = 25.11; transcription factor 7-like 1 (T-cell specific, HMG-box)" ID="ID_636444272" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FBXW11: 1.16-fold Up; FDR = 0.106; PValue = 0.0378; mean CPM = 64.90; F-box and WD repeat domain containing 11" ID="ID_493087367" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R5E: 1.17-fold Up; FDR = 0.112; PValue = 0.04; mean CPM = 30.87; Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform; Uncharacterized protein" ID="ID_94242251" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND1: 1.17-fold Up; FDR = 0.121; PValue = 0.0443; mean CPM = 867.3; cyclin D1" ID="ID_978919510" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_1439687687" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000024051: 1.19-fold Up; FDR = 0.136; PValue = 0.0509; mean CPM = 16.04; Uncharacterized protein" ID="ID_49636940" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_858145013" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VANGL2: 1.48-fold Down; FDR = 0.143; PValue = 0.0542; mean CPM = 2.357; vang-like 2 (van gogh, Drosophila)" ID="ID_238455176" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_22575060" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD1: 1.23-fold Down; FDR = 0.154; PValue = 0.0592; mean CPM = 31.65; frizzled homolog 1 (Drosophila)" ID="ID_275858124" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NKD1: 2.25-fold Down; FDR = 0.161; PValue = 0.0628; mean CPM = 0.9036; naked cuticle homolog 1 (Drosophila)" ID="ID_1396237526" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ROCK2: 1.14-fold Up; FDR = 0.166; PValue = 0.065; mean CPM = 247.7; Rho-associated, coiled-coil containing protein kinase 2" ID="ID_1445525423" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SKP1: 1.14-fold Up; FDR = 0.176; PValue = 0.07; mean CPM = 88.20; S-phase kinase-associated protein 1" ID="ID_1608481667" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT3A: 2.28-fold Down; FDR = 0.2; PValue = 0.0823; mean CPM = 0.8811; wingless-type MMTV integration site family, member 3A" ID="ID_195040876" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000041158: 1.15-fold Up; FDR = 0.216; PValue = 0.0905; mean CPM = 24.28; Uncharacterized protein" ID="ID_51340850" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSNK1E: 1.13-fold Down; FDR = 0.221; PValue = 0.0928; mean CPM = 85.29; casein kinase 1, epsilon" ID="ID_1964600890" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSEN1: 1.12-fold Up; FDR = 0.233; PValue = 0.0992; mean CPM = 62.12; presenilin 1" ID="ID_1470827569" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT3: 1.4-fold Up; FDR = 0.304; PValue = 0.138; mean CPM = 1.843; wingless-type MMTV integration site family, member 3" ID="ID_418641806" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EP300: 1.11-fold Up; FDR = 0.312; PValue = 0.142; mean CPM = 162.8; E1A binding protein p300" ID="ID_409995768" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND2: 1.2-fold Up; FDR = 0.335; PValue = 0.155; mean CPM = 76.91; cyclin D2" ID="ID_64191653" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD6: 1.11-fold Down; FDR = 0.347; PValue = 0.162; mean CPM = 39.10; frizzled homolog 6 (Drosophila)" ID="ID_1474408269" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP53: 1.11-fold Down; FDR = 0.364; PValue = 0.172; mean CPM = 33.25; tumor protein p53" ID="ID_866651946" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APC: 1.1-fold Down; FDR = 0.367; PValue = 0.174; mean CPM = 127.5; adenomatous polyposis coli" ID="ID_18976455" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R5C: 1.14-fold Up; FDR = 0.391; PValue = 0.189; mean CPM = 54.95; protein phosphatase 2, regulatory subunit B', gamma" ID="ID_492997223" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD5: 1.34-fold Down; FDR = 0.405; PValue = 0.197; mean CPM = 2.107; frizzled homolog 5 (Drosophila)" ID="ID_1448519652" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BTRC: 1.11-fold Down; FDR = 0.413; PValue = 0.202; mean CPM = 17.40; beta-transducin repeat containing" ID="ID_1578235081" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RBX1: 1.09-fold Up; FDR = 0.413; PValue = 0.202; mean CPM = 67.97; ring-box 1" ID="ID_1829141106" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NKD2: 1.75-fold Up; FDR = 0.422; PValue = 0.207; mean CPM = 0.9072; naked cuticle homolog 2 (Drosophila)" ID="ID_1606109151" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DAAM1: 1.11-fold Down; FDR = 0.457; PValue = 0.229; mean CPM = 23.67; dishevelled associated activator of morphogenesis 1" ID="ID_884742907" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC1: 1.11-fold Down; FDR = 0.457; PValue = 0.23; mean CPM = 19.06; Uncharacterized protein" ID="ID_1164448325" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DKK4: 1.7-fold Up; FDR = 0.476; PValue = 0.242; mean CPM = 0.9028; dickkopf homolog 4 (Xenopus laevis)" ID="ID_667009363" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT9A: 1.43-fold Down; FDR = 0.505; PValue = 0.262; mean CPM = 2.172; wingless-type MMTV integration site family, member 9A" ID="ID_1642626977" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP3CB: 1.08-fold Up; FDR = 0.514; PValue = 0.268; mean CPM = 76.44; protein phosphatase 3, catalytic subunit, beta isozyme" ID="ID_866360990" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WIF1: 1.61-fold Down; FDR = 0.541; PValue = 0.287; mean CPM = 0.8746; WNT inhibitory factor 1" ID="ID_1557533214" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCG: 1.47-fold Down; FDR = 0.609; PValue = 0.336; mean CPM = 0.9297; protein kinase C, gamma" ID="ID_1929126118" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT2B: 1.29-fold Down; FDR = 0.621; PValue = 0.345; mean CPM = 1.575; wingless-type MMTV integration site family, member 2B" ID="ID_121558324" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AXIN1: 1.06-fold Up; FDR = 0.661; PValue = 0.376; mean CPM = 66.56; axin 1" ID="ID_1091920854" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LEF1: 1.2-fold Up; FDR = 0.691; PValue = 0.4; mean CPM = 2.488; lymphoid enhancer-binding factor 1" ID="ID_1960245902" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DVL2: 1.06-fold Up; FDR = 0.708; PValue = 0.414; mean CPM = 30.54; dishevelled, dsh homolog 2 (Drosophila)" ID="ID_1269682408" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCB: 1.86-fold Up; FDR = 0.727; PValue = 0.43; mean CPM = 0.8705; protein kinase C, beta" ID="ID_1939927023" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBL1XR1: 1.06-fold Up; FDR = 0.729; PValue = 0.431; mean CPM = 74.21; transducin (beta)-like 1 X-linked receptor 1" ID="ID_1014334690" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACG: 1.51-fold Down; FDR = 0.795; PValue = 0.491; mean CPM = 0.8026; protein kinase, cAMP-dependent, catalytic, gamma" ID="ID_295147586" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2CA: 1.05-fold Up; FDR = 0.8; PValue = 0.497; mean CPM = 62.78; protein phosphatase 2, catalytic subunit, alpha isozyme" ID="ID_1442438443" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSNK1A1L: 1.31-fold Up; FDR = 0.806; PValue = 0.502; mean CPM = 0.9242; casein kinase 1, alpha 1-like" ID="ID_1102029350" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT16: 1.27-fold Down; FDR = 0.857; PValue = 0.571; mean CPM = 0.9003; wingless-type MMTV integration site family, member 16" ID="ID_1103696377" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP7: 1.39-fold Down; FDR = 0.89; PValue = 0.613; mean CPM = 0.8356; Uncharacterized protein" ID="ID_240819583" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT11: 1.18-fold Up; FDR = 0.903; PValue = 0.641; mean CPM = 1.340; wingless-type MMTV integration site family, member 11" ID="ID_1023706193" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DKK2: 1.21-fold Up; FDR = 0.903; PValue = 0.645; mean CPM = 0.9269; dickkopf homolog 2 (Xenopus laevis)" ID="ID_1523583065" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOSL1: 1.04-fold Up; FDR = 0.903; PValue = 0.657; mean CPM = 64.19; FOS-like antigen 1" ID="ID_1594295586" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000021684: 1.44-fold Up; FDR = 0.903; PValue = 0.662; mean CPM = 0.8513; Uncharacterized protein" ID="ID_524200400" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD4: 1.03-fold Down; FDR = 0.906; PValue = 0.666; mean CPM = 43.02; SMAD family member 4" ID="ID_1604331541" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOX17: 1.19-fold Down; FDR = 0.906; PValue = 0.668; mean CPM = 0.8003; SRY (sex determining region Y)-box 17" ID="ID_1077542976" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACB: 1.03-fold Up; FDR = 0.911; PValue = 0.694; mean CPM = 30.10; protein kinase, cAMP-dependent, catalytic, beta" ID="ID_1338140069" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SFRP5: 1.18-fold Down; FDR = 0.917; PValue = 0.718; mean CPM = 0.8162; secreted frizzled-related protein 5" ID="ID_1839721188" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CER1: 1.24-fold Down; FDR = 0.92; PValue = 0.722; mean CPM = 0.8049; Cerberus-related protein; Uncharacterized protein" ID="ID_4463685" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SENP2: 1.02-fold Up; FDR = 0.925; PValue = 0.732; mean CPM = 51.25; SUMO1/sentrin/SMT3 specific peptidase 2" ID="ID_792297398" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTBP2: 1.24-fold Up; FDR = 0.934; PValue = 0.746; mean CPM = 0.8168; C-terminal binding protein 2" ID="ID_286940151" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXXC4: 1.29-fold Down; FDR = 0.939; PValue = 0.753; mean CPM = 0.8071; CXXC finger 4" ID="ID_14912713" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AC130454.2: 1.18-fold Up; FDR = 0.942; PValue = 0.76; mean CPM = 0.8360; Calcineurin B homologous protein 2 (Hepatocellular carcinoma-associated antigen 520)" ID="ID_450911614" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SFRP4: 1.39-fold Up; FDR = 0.948; PValue = 0.771; mean CPM = 0.8499; Macaca mulatta secreted frizzled-related protein 4 (SFRP4), mRNA." ID="ID_831977825" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC3: 1.03-fold Down; FDR = 0.952; PValue = 0.78; mean CPM = 13.31; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3" ID="ID_477455602" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSNK2B: 1.02-fold Down; FDR = 0.956; PValue = 0.787; mean CPM = 77.24; Casein kinase II subunit beta (CK II beta)(Phosvitin)(Protein G5a)" ID="ID_1377420624" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LRP6: 1.02-fold Down; FDR = 0.962; PValue = 0.796; mean CPM = 85.24; low density lipoprotein receptor-related protein 6" ID="ID_1802395410" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_1746881568" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_1570419037" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SFRP1: 1.02-fold Up; FDR = 0.972; PValue = 0.814; mean CPM = 307.1; secreted frizzled-related protein 1" ID="ID_539590085" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT8B: 1.21-fold Down; FDR = 0.987; PValue = 0.838; mean CPM = 0.8506; wingless-type MMTV integration site family, member 8B" ID="ID_936681117" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREBBP: 1.01-fold Down; FDR = 0.993; PValue = 0.847; mean CPM = 137.7; CREB binding protein" ID="ID_354285472" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT2: 1.07-fold Down; FDR = 1; PValue = 0.888; mean CPM = 0.8103; wingless-type MMTV integration site family member 2" ID="ID_109949972" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R5B: 1.01-fold Down; FDR = 1; PValue = 0.898; mean CPM = 92.91; protein phosphatase 2, regulatory subunit B', beta" ID="ID_1620416217" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD3: 1.03-fold Up; FDR = 1; PValue = 0.903; mean CPM = 1.636; frizzled homolog 3 (Drosophila)" ID="ID_541169478" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD10: 1.04-fold Down; FDR = 1; PValue = 0.919; mean CPM = 0.8435; frizzled homolog 10 (Drosophila)" ID="ID_253020174" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHD8: 1.01-fold Down; FDR = 1; PValue = 0.921; mean CPM = 155.1; chromodomain helicase DNA binding protein 8" ID="ID_270280916" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT6: 1.13-fold Down; FDR = 1; PValue = 0.956; mean CPM = 0.8230; wingless-type MMTV integration site family, member 6" ID="ID_72304801" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLK: No Change; FDR = 1; PValue = 0.97; mean CPM = 11.78; nemo-like kinase" ID="ID_1211976423" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT9B: 1.03-fold Up; FDR = 1; PValue = 0.991; mean CPM = 0.8041; wingless-type MMTV integration site family, member 9B" ID="ID_143228325" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-2 : FDR = 0.000241, PValue = 0.000218" ID="ID_287260855" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="STAT5A: 2.28-fold Up; FDR = 6.87e-14; PValue = 8.58e-16; mean CPM = 21.55; signal transducer and activator of transcription 5A" ID="ID_1389712618" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_177438443" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2B: 3.54-fold Up; FDR = 1.24e-07; PValue = 7.07e-09; mean CPM = 5.971; PTK2B protein tyrosine kinase 2 beta" ID="ID_1296509156" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1336361086" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_576009121" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_661541168" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_936908268" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_1418730884" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1468785344" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK3: 2.31-fold Up; FDR = 0.00186; PValue = 0.000342; mean CPM = 2.154; Janus kinase 3" ID="ID_337746258" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1S1: 1.31-fold Down; FDR = 0.00202; PValue = 0.000375; mean CPM = 35.32; AKT1 substrate 1 (proline-rich)" ID="ID_829813345" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLEKHO1: 1.3-fold Down; FDR = 0.00647; PValue = 0.00142; mean CPM = 47.00; pleckstrin homology domain containing, family O member 1" ID="ID_1301554688" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSNK2A2: 1.28-fold Up; FDR = 0.0129; PValue = 0.00314; mean CPM = 19.86; casein kinase 2, alpha prime polypeptide" ID="ID_1667088474" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_65955528" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_124896792" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_785648506" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_423961477" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS2: 1.17-fold Up; FDR = 0.1; PValue = 0.0353; mean CPM = 31.79; son of sevenless homolog 2 (Drosophila)" ID="ID_901878098" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1077272486" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1516541322" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_1545192690" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_655203982" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_1155907460" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1030061752" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3C2B: 1.17-fold Down; FDR = 0.406; PValue = 0.198; mean CPM = 6.381; phosphoinositide-3-kinase, class 2, beta polypeptide" ID="ID_664262446" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_596389546" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_1853443036" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_1062600067" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1951279220" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2RA: 1.08-fold Up; FDR = 0.945; PValue = 0.766; mean CPM = 0.8493; interleukin 2 receptor, alpha" ID="ID_84165172" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_1232811763" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSNK2B: 1.02-fold Down; FDR = 0.956; PValue = 0.787; mean CPM = 77.24; Casein kinase II subunit beta (CK II beta)(Phosvitin)(Protein G5a)" ID="ID_1618364460" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3C2A: 1.02-fold Up; FDR = 0.957; PValue = 0.788; mean CPM = 84.41; phosphoinositide-3-kinase, class 2, alpha polypeptide" ID="ID_561367822" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SYK: 1.11-fold Up; FDR = 1; PValue = 0.977; mean CPM = 0.8420; spleen tyrosine kinase" ID="ID_501686834" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2: 1.03-fold Up; FDR = 1; PValue = 0.998; mean CPM = 0.7974; interleukin 2" ID="ID_1026038931" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="4-1BB: FDR = 0.00202, PValue = 0.00187" ID="ID_1127172612" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_778050173" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_262318034" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF1: 2.6-fold Down; FDR = 1.48e-05; PValue = 1.46e-06; mean CPM = 20.19; TNF receptor-associated factor 1" ID="ID_984438891" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP4K4: 1.4-fold Down; FDR = 3.08e-05; PValue = 3.27e-06; mean CPM = 242.8; mitogen-activated protein kinase kinase kinase kinase 4" ID="ID_1615028394" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_1147133536" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF2: 1.34-fold Up; FDR = 0.000403; PValue = 6.01e-05; mean CPM = 39.83; activating transcription factor 2" ID="ID_1616188707" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_63571942" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP4K5: 1.29-fold Up; FDR = 0.00246; PValue = 0.000468; mean CPM = 53.45; mitogen-activated protein kinase kinase kinase kinase 5" ID="ID_984230435" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_3833725" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K14: 1.47-fold Down; FDR = 0.00704; PValue = 0.00157; mean CPM = 9.470; mitogen-activated protein kinase kinase kinase 14" ID="ID_1200897914" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBID: 1.47-fold Down; FDR = 0.0247; PValue = 0.0067; mean CPM = 6.446; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta" ID="ID_1908713669" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIE: 1.3-fold Down; FDR = 0.0272; PValue = 0.00752; mean CPM = 16.93; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon" ID="ID_1593649099" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1085788919" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKAP: 1.19-fold Down; FDR = 0.0434; PValue = 0.013; mean CPM = 50.22; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein" ID="ID_1327070645" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIZ: 1.23-fold Up; FDR = 0.0949; PValue = 0.033; mean CPM = 91.08; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta" ID="ID_1036630375" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_1655798761" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_143143132" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPIL5: 1.22-fold Up; FDR = 0.185; PValue = 0.0742; mean CPM = 10.27; peptidylprolyl isomerase (cyclophilin)-like 5" ID="ID_613970028" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1139584688" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K5: 1.21-fold Down; FDR = 0.6; PValue = 0.33; mean CPM = 8.023; mitogen-activated protein kinase kinase kinase 5" ID="ID_1891739374" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_537141723" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_713155254" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF9: 1.28-fold Down; FDR = 0.911; PValue = 0.7; mean CPM = 0.8318; tumor necrosis factor receptor superfamily, member 9" ID="ID_575612422" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKE: 1.03-fold Up; FDR = 0.929; PValue = 0.737; mean CPM = 21.61; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon" ID="ID_438541898" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL4: 1.27-fold Down; FDR = 0.933; PValue = 0.745; mean CPM = 0.8077; interleukin 4" ID="ID_217314834" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_1863822741" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2: 1.03-fold Up; FDR = 1; PValue = 0.998; mean CPM = 0.7974; interleukin 2" ID="ID_1554118005" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- </node>
- </node>
- <node TEXT="WikiPathways gene set collection" POSITION="right" ID="ID_1133721324" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CAMERA gene set test" ID="ID_568375046" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="Type II interferon signaling (IFNG) (WP619:Rev45027): Upregulated, FDR = 0.000388, PValue = 2.02e-06" ID="ID_1381705727" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TAP1: 8.86-fold Up; FDR = 4.25e-27; PValue = 3.99e-31; mean CPM = 524.4; Antigen peptide transporter 1 (APT1)(Peptide transporter TAP1)(ATP-binding cassette sub-family B member 2)(Peptide supply factor 1)(Peptide transporter PSF1)(PSF-1)(Peptide transporter involved in antigen processing 1)(Really interesting new gene 4 /.../n)" ID="ID_814472178" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GBP1: 54.9-fold Up; FDR = 3.11e-24; PValue = 2.93e-27; mean CPM = 1282; guanylate binding protein 1, interferon-inducible, 67kDa" ID="ID_276725076" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMB9: 18.6-fold Up; FDR = 5.15e-24; PValue = 5.86e-27; mean CPM = 380.3; proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)" ID="ID_534054572" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFI6: 19-fold Up; FDR = 6.4e-22; PValue = 1.59e-24; mean CPM = 1370; interferon, alpha-inducible protein 6" ID="ID_1848528266" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFIT2: 80.8-fold Up; FDR = 9.69e-22; PValue = 2.5e-24; mean CPM = 473.4; interferon-induced protein with tetratricopeptide repeats 2" ID="ID_1161540541" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL10: 462-fold Up; FDR = 1.01e-21; PValue = 2.65e-24; mean CPM = 286.2; Macaca mulatta chemokine (C-X-C motif) ligand 10 (CXCL10), mRNA." ID="ID_1809921366" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000027180: 6.97-fold Up; FDR = 1.24e-21; PValue = 3.39e-24; mean CPM = 285.4; Uncharacterized protein" ID="ID_1007394212" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF1: 18.6-fold Up; FDR = 1.53e-21; PValue = 4.24e-24; mean CPM = 240.7; interferon regulatory factor 1" ID="ID_1269311711" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000005183: 4.07-fold Up; FDR = 2.87e-21; PValue = 8.51e-24; mean CPM = 164.7; Uncharacterized protein" ID="ID_804403845" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="OAS1: 41-fold Up; FDR = 1.01e-20; PValue = 3.28e-23; mean CPM = 37.38; Macaca mulatta 2',5'-oligoadenylate synthetase 1, 40/46kDa (OAS1), mRNA." ID="ID_1981912522" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF9: 3.85-fold Up; FDR = 2.6e-19; PValue = 1.12e-21; mean CPM = 106.4; interferon regulatory factor 9" ID="ID_333256147" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL9: 345-fold Up; FDR = 4.16e-19; PValue = 1.97e-21; mean CPM = 175.7; Macaca mulatta chemokine (C-X-C motif) ligand 9 (CXCL9), mRNA." ID="ID_486154681" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT2: 2.67-fold Up; FDR = 8.02e-19; PValue = 4.03e-21; mean CPM = 185.6; signal transducer and activator of transcription 2, 113kDa" ID="ID_541258835" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_935683966" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1716963393" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF2: 3.25-fold Up; FDR = 2.61e-18; PValue = 1.48e-20; mean CPM = 32.37; interferon regulatory factor 2" ID="ID_81986061" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2AK2: 3.01-fold Up; FDR = 6.08e-18; PValue = 3.74e-20; mean CPM = 47.85; eukaryotic translation initiation factor 2-alpha kinase 2" ID="ID_1471344129" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CIITA: 45.8-fold Up; FDR = 1.14e-17; PValue = 7.44e-20; mean CPM = 27.80; class II, major histocompatibility complex, transactivator" ID="ID_1357746149" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICAM1: 24.6-fold Up; FDR = 2.39e-17; PValue = 1.64e-19; mean CPM = 232.4; intercellular adhesion molecule 1" ID="ID_1244406491" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ISG15: 15.5-fold Up; FDR = 2.16e-15; PValue = 2.02e-17; mean CPM = 55.60; ISG15 ubiquitin-like modifier" ID="ID_1708468579" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF8: 11.4-fold Up; FDR = 6e-09; PValue = 2.46e-10; mean CPM = 5.558; interferon regulatory factor 8" ID="ID_1636946903" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS3: 1.69-fold Up; FDR = 0.000994; PValue = 0.000167; mean CPM = 37.76; suppressor of cytokine signaling 3" ID="ID_1230510479" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR1: 1.31-fold Up; FDR = 0.00151; PValue = 0.000268; mean CPM = 37.77; interferon gamma receptor 1" ID="ID_136502700" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HIST1H4F: 1.68-fold Up; FDR = 0.0162; PValue = 0.00411; mean CPM = 53.41; histone cluster 1, H4f" ID="ID_587146885" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR2: 1.23-fold Up; FDR = 0.0258; PValue = 0.00707; mean CPM = 46.52; interferon gamma receptor 2 (interferon gamma transducer 1)" ID="ID_250493761" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HIST1H4K: 1.36-fold Down; FDR = 0.0491; PValue = 0.015; mean CPM = 23.81; Histone H4" ID="ID_1777416259" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_553186300" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF4: 2.95-fold Down; FDR = 0.124; PValue = 0.0456; mean CPM = 0.9773; interferon regulatory factor 4" ID="ID_1877245719" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HIST1H4H: 1.22-fold Up; FDR = 0.156; PValue = 0.0604; mean CPM = 205.4; histone cluster 1, H4h" ID="ID_576846656" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HIST1H4C: 1.33-fold Down; FDR = 0.204; PValue = 0.0842; mean CPM = 188.3; histone cluster 1, H4c" ID="ID_1079369344" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HIST1H4L: 1.43-fold Down; FDR = 0.211; PValue = 0.0877; mean CPM = 23.77; histone cluster 1, H4l" ID="ID_1183414691" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HIST4H4: 1.23-fold Down; FDR = 0.234; PValue = 0.0995; mean CPM = 130.3; histone cluster 4, H4" ID="ID_518935105" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_1722835784" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HIST1H4D: 1.2-fold Down; FDR = 0.655; PValue = 0.371; mean CPM = 77.97; histone cluster 1, H4d" ID="ID_716843422" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_341981720" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCD: 1.06-fold Up; FDR = 0.696; PValue = 0.404; mean CPM = 37.45; protein kinase C, delta" ID="ID_1753143266" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYBB: 1.52-fold Up; FDR = 0.705; PValue = 0.412; mean CPM = 0.9872; cytochrome b-245, beta polypeptide" ID="ID_343035779" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNB1: 1.79-fold Up; FDR = 0.731; PValue = 0.433; mean CPM = 0.8526; interferon, beta 1, fibroblast" ID="ID_480280912" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HIST1H4B: 1.09-fold Up; FDR = 0.804; PValue = 0.5; mean CPM = 159.3; histone cluster 1, H4b" ID="ID_534965963" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HIST2H4B: 1.09-fold Down; FDR = 0.849; PValue = 0.559; mean CPM = 390.8; histone cluster 2, H4b" ID="ID_1354954686" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_1291010338" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HIST1H4K: 1.07-fold Down; FDR = 0.909; PValue = 0.685; mean CPM = 58.36; histone cluster 1, H4k" ID="ID_734710442" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOS2: 1.4-fold Down; FDR = 0.917; PValue = 0.718; mean CPM = 0.8546; nitric oxide synthase 2, inducible" ID="ID_230327028" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPI1: 1.12-fold Down; FDR = 0.935; PValue = 0.747; mean CPM = 1.030; spleen focus forming virus (SFFV) proviral integration oncogene spi1" ID="ID_91677436" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="REG1A: No Change; FDR = 1; PValue = 1; mean CPM = 0.7990; regenerating islet-derived 1 alpha" ID="ID_97301005" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="REG1A: No Change; FDR = 1; PValue = 1; mean CPM = 0.7825; Uncharacterized protein" ID="ID_903313318" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HIST1H4A: No Change; FDR = 1; PValue = 1; mean CPM = 0.7841; histone cluster 1, H4a" ID="ID_1896483189" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="NOD pathway (WP1433:Rev45352): Upregulated, FDR = 0.0296, PValue = 0.000309" ID="ID_283766139" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="AIM2: 7.87-fold Up; FDR = 4.34e-20; PValue = 1.57e-22; mean CPM = 34.80; absent in melanoma 2" ID="ID_1087185224" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP5: 68-fold Up; FDR = 3.54e-19; PValue = 1.64e-21; mean CPM = 7.240; caspase 5, apoptosis-related cysteine peptidase" ID="ID_1168834312" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_1851609011" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK2: 3.75-fold Up; FDR = 6.1e-16; PValue = 5.38e-18; mean CPM = 68.21; receptor-interacting serine-threonine kinase 2" ID="ID_932728365" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CARD6: 2.33-fold Up; FDR = 1.15e-12; PValue = 1.89e-14; mean CPM = 30.09; caspase recruitment domain family, member 6" ID="ID_1714218385" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CARD8: 2.48-fold Up; FDR = 2.44e-11; PValue = 5.59e-13; mean CPM = 14.84; caspase recruitment domain family, member 8" ID="ID_1289823145" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CARD8: 2.02-fold Up; FDR = 1.41e-09; PValue = 4.93e-11; mean CPM = 15.89; caspase recruitment domain family, member 8" ID="ID_971632523" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_794349958" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRDM1: 3.05-fold Up; FDR = 3.55e-08; PValue = 1.78e-09; mean CPM = 8.715; PR domain containing 1, with ZNF domain" ID="ID_907142888" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLRC4: 6.6-fold Up; FDR = 8.52e-08; PValue = 4.67e-09; mean CPM = 3.347; NLR family, CARD domain containing 4" ID="ID_910902816" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90AA1: 1.41-fold Up; FDR = 4.17e-05; PValue = 4.62e-06; mean CPM = 609.6; heat shock protein 90kDa alpha (cytosolic), class A member 2" ID="ID_1625457927" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CARD9: 1.53-fold Up; FDR = 9.57e-05; PValue = 1.18e-05; mean CPM = 16.72; caspase recruitment domain family, member 9" ID="ID_643419071" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOD1: 1.63-fold Up; FDR = 0.000193; PValue = 2.61e-05; mean CPM = 58.36; nucleotide-binding oligomerization domain containing 1" ID="ID_912551744" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SUGT1: 1.35-fold Up; FDR = 0.000193; PValue = 2.61e-05; mean CPM = 54.75; SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)" ID="ID_1208194610" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_770605637" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL18: 1.5-fold Down; FDR = 0.00981; PValue = 0.0023; mean CPM = 6.489; interleukin 18 (interferon-gamma-inducing factor)" ID="ID_1234649055" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_387188743" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XIAP: 1.17-fold Up; FDR = 0.177; PValue = 0.0706; mean CPM = 19.21; X-linked inhibitor of apoptosis" ID="ID_1797065629" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACAP1: 1.42-fold Down; FDR = 0.179; PValue = 0.0717; mean CPM = 2.333; ArfGAP with coiled-coil, ankyrin repeat and PH domains 1" ID="ID_1995790547" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP7: 1.15-fold Up; FDR = 0.218; PValue = 0.0916; mean CPM = 21.49; caspase 7, apoptosis-related cysteine peptidase" ID="ID_1711472137" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PYCARD: 1.38-fold Down; FDR = 0.241; PValue = 0.103; mean CPM = 3.110; PYD and CARD domain containing" ID="ID_1047915468" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLRP3: 1.84-fold Down; FDR = 0.32; PValue = 0.147; mean CPM = 0.9630; NLR family, pyrin domain containing 3" ID="ID_590884826" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COPS6: 1.06-fold Down; FDR = 0.655; PValue = 0.371; mean CPM = 93.74; COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)" ID="ID_591338817" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_566738956" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90AA1: 1.8-fold Up; FDR = 0.749; PValue = 0.449; mean CPM = 0.8328; heat shock protein 90kDa alpha (cytosolic), class A member 1" ID="ID_1003187323" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MEFV: 1.13-fold Up; FDR = 0.813; PValue = 0.51; mean CPM = 6.740; Mediterranean fever" ID="ID_1013579106" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_821299499" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOD2: 1.17-fold Up; FDR = 0.866; PValue = 0.583; mean CPM = 1.911; nucleotide-binding oligomerization domain containing 2" ID="ID_1129790974" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLRP10: 1.48-fold Up; FDR = 0.868; PValue = 0.586; mean CPM = 0.8220; NLR family, pyrin domain containing 10" ID="ID_226227350" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DUOX2: 1.22-fold Down; FDR = 0.898; PValue = 0.625; mean CPM = 1.000; dual oxidase 2" ID="ID_1158165129" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLRP7: 1.15-fold Down; FDR = 0.906; PValue = 0.672; mean CPM = 0.7909; NLR family, pyrin domain containing 7" ID="ID_1929744013" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_190400833" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP9: 1.01-fold Up; FDR = 1; PValue = 0.908; mean CPM = 19.86; caspase 9, apoptosis-related cysteine peptidase" ID="ID_1814016352" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLRP4: 1.05-fold Down; FDR = 1; PValue = 0.911; mean CPM = 0.8249; NLR family, pyrin domain containing 4" ID="ID_1546229562" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Complement Activation, Classical Pathway (WP545:Rev41148): Upregulated, FDR = 0.0605, PValue = 0.000945" ID="ID_551720067" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="C4B: 24.3-fold Up; FDR = 1.01e-20; PValue = 3.32e-23; mean CPM = 65.82; Complement C4-B Precursor (Basic complement C4)(C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3) [Contains Complement C4 beta chain;Complement C4-B alpha chain;C4a anaphylatoxin;C4b-B;C4d-B;Complement C4 gamma chain]" ID="ID_766068977" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C2: 4.8-fold Up; FDR = 3.21e-17; PValue = 2.26e-19; mean CPM = 200.3; Uncharacterized protein" ID="ID_739575395" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C3: 5.35-fold Up; FDR = 5.79e-07; PValue = 3.91e-08; mean CPM = 19.68; complement component 3" ID="ID_1182650005" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C5: 2.29-fold Up; FDR = 0.0212; PValue = 0.00561; mean CPM = 1.418; complement component 5" ID="ID_1785053165" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C1QB: 2.62-fold Up; FDR = 0.0887; PValue = 0.0304; mean CPM = 1.092; complement component 1, q subcomponent, B chain" ID="ID_1836840631" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C1QC: 2.02-fold Up; FDR = 0.203; PValue = 0.0839; mean CPM = 1.322; complement component 1, q subcomponent, C chain" ID="ID_977043346" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MASP1: 1.46-fold Down; FDR = 0.264; PValue = 0.115; mean CPM = 4.467; mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)" ID="ID_1946342315" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C8B: 2.74-fold Up; FDR = 0.396; PValue = 0.192; mean CPM = 0.8553; complement component 8, beta polypeptide" ID="ID_619258278" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C9: 1.41-fold Up; FDR = 0.505; PValue = 0.262; mean CPM = 1.295; complement component 9" ID="ID_904378269" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C6: 1.72-fold Down; FDR = 0.856; PValue = 0.57; mean CPM = 0.8334; complement component 6" ID="ID_1862163248" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C8A: 1.06-fold Up; FDR = 0.968; PValue = 0.808; mean CPM = 0.8260; complement component 8, alpha polypeptide" ID="ID_1198996061" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C7: 1.11-fold Up; FDR = 1; PValue = 0.883; mean CPM = 0.8197; complement component 7" ID="ID_450530996" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="EPO Receptor Signaling (WP581:Rev41162): Upregulated, FDR = 0.492, PValue = 0.0105" ID="ID_1588118569" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_462219287" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1122774454" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5A: 2.28-fold Up; FDR = 6.87e-14; PValue = 8.58e-16; mean CPM = 21.55; signal transducer and activator of transcription 5A" ID="ID_1145744223" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_1815015423" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPRU: 2.57-fold Down; FDR = 1.5e-09; PValue = 5.3e-11; mean CPM = 17.80; Uncharacterized protein" ID="ID_913707446" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_469280091" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRS1: 2.78-fold Up; FDR = 7.67e-09; PValue = 3.19e-10; mean CPM = 26.55; Uncharacterized protein" ID="ID_64428217" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_192219554" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_423063977" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPRC: 6.08-fold Up; FDR = 0.000285; PValue = 4.07e-05; mean CPM = 1.220; protein tyrosine phosphatase, receptor type, C" ID="ID_1099776032" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CISH: 1.95-fold Up; FDR = 0.00116; PValue = 0.0002; mean CPM = 5.083; cytokine inducible SH2-containing protein" ID="ID_315994319" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EPOR: 1.56-fold Down; FDR = 0.014; PValue = 0.00347; mean CPM = 3.898; erythropoietin receptor" ID="ID_1529820251" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_638820595" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1278866871" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_415177578" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_1616454363" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_408416643" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EPO: 1.77-fold Up; FDR = 0.39; PValue = 0.188; mean CPM = 0.9174; Macaca mulatta erythropoietin (EPO), mRNA." ID="ID_1060218242" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_625480729" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_230089568" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASA1: 1.03-fold Down; FDR = 0.909; PValue = 0.69; mean CPM = 103.7; Ras GTPase-activating protein 1 isoform 1; Uncharacterized protein" ID="ID_1159530635" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_1615455552" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Serotonin Transporter Activity (WP1455:Rev45033): Downregulated, FDR = 0.492, PValue = 0.0136" ID="ID_1758172713" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="ITGB3: 5.02-fold Down; FDR = 1.72e-09; PValue = 6.17e-11; mean CPM = 43.21; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)" ID="ID_985654105" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB1I1: 1.86-fold Down; FDR = 2.06e-08; PValue = 9.7e-10; mean CPM = 130.1; Uncharacterized protein" ID="ID_558062730" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SCAMP2: 1.5-fold Down; FDR = 2.72e-07; PValue = 1.69e-08; mean CPM = 69.29; secretory carrier membrane protein 2" ID="ID_1461540015" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2CB: 1.35-fold Up; FDR = 0.000215; PValue = 2.96e-05; mean CPM = 59.68; protein phosphatase 2, catalytic subunit, beta isozyme" ID="ID_524561923" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C17orf57: 5.51-fold Down; FDR = 0.000238; PValue = 3.33e-05; mean CPM = 1.571; EF-hand domain-containing protein C17orf57" ID="ID_251612206" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STX1A: 1.45-fold Down; FDR = 0.00178; PValue = 0.000326; mean CPM = 10.16; syntaxin 1A (brain)" ID="ID_1920707838" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAOA: 1.43-fold Down; FDR = 0.00532; PValue = 0.00114; mean CPM = 367.7; monoamine oxidase A" ID="ID_1352182104" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC6A4: 1.75-fold Down; FDR = 0.374; PValue = 0.178; mean CPM = 0.9214; Macaca mulatta solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 (SLC6A4), mRNA." ID="ID_798475565" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_140738609" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Apoptosis (WP254:Rev41184): Upregulated, FDR = 0.492, PValue = 0.0154" ID="ID_1801350260" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="IRF1: 18.6-fold Up; FDR = 1.53e-21; PValue = 4.24e-24; mean CPM = 240.7; interferon regulatory factor 1" ID="ID_863173253" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF2: 3.25-fold Up; FDR = 2.61e-18; PValue = 1.48e-20; mean CPM = 32.37; interferon regulatory factor 2" ID="ID_1845265546" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF7: 14.8-fold Up; FDR = 7.66e-18; PValue = 4.82e-20; mean CPM = 11.54; Macaca mulatta interferon regulatory factor 7 (IRF7), mRNA." ID="ID_1914310204" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_1866109169" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF10: 44.5-fold Up; FDR = 2.83e-16; PValue = 2.4e-18; mean CPM = 6.029; Tumor necrosis factor ligand superfamily member 10 isoform 1; Uncharacterized protein" ID="ID_584884566" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PMAIP1: 8.66-fold Up; FDR = 1.12e-12; PValue = 1.84e-14; mean CPM = 31.02; Phorbol-12-myristate-13-acetate-induced protein 1; Uncharacterized protein" ID="ID_813708790" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP4: 4.99-fold Up; FDR = 6.91e-12; PValue = 1.4e-13; mean CPM = 56.06; Caspase" ID="ID_1865332745" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC2: 1.96-fold Up; FDR = 1.01e-10; PValue = 2.62e-12; mean CPM = 53.58; baculoviral IAP repeat-containing 2" ID="ID_1499410716" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CFLAR: 1.87-fold Up; FDR = 5.09e-10; PValue = 1.61e-11; mean CPM = 103.3; CASP8 and FADD-like apoptosis regulator" ID="ID_668573164" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BID: 1.66-fold Up; FDR = 5.41e-09; PValue = 2.19e-10; mean CPM = 35.19; BH3 interacting domain death agonist" ID="ID_601714906" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_921928777" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1984708142" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_1772908473" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L1: 1.51-fold Up; FDR = 9.13e-07; PValue = 6.52e-08; mean CPM = 66.15; Bcl-2-like protein 1; Bcl-2-like protein 1 isoform 1; Uncharacterized protein" ID="ID_1897797680" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC3: 2.79-fold Up; FDR = 1.74e-06; PValue = 1.32e-07; mean CPM = 95.34; baculoviral IAP repeat-containing 3" ID="ID_1063386225" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1B: 2.24-fold Up; FDR = 2.68e-06; PValue = 2.16e-07; mean CPM = 19.44; tumor necrosis factor receptor superfamily, member 1B" ID="ID_1662474330" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1: 5.76-fold Down; FDR = 6.73e-06; PValue = 6.04e-07; mean CPM = 1.536; insulin-like growth factor 1 (somatomedin C)" ID="ID_542360231" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1R: 1.51-fold Down; FDR = 1.02e-05; PValue = 9.61e-07; mean CPM = 213.2; insulin-like growth factor 1 receptor" ID="ID_1881834409" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BNIP3L: 1.42-fold Up; FDR = 1.15e-05; PValue = 1.09e-06; mean CPM = 219.7; BCL2/adenovirus E1B 19kDa interacting protein 3-like" ID="ID_371802072" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF1: 2.6-fold Down; FDR = 1.48e-05; PValue = 1.46e-06; mean CPM = 20.19; TNF receptor-associated factor 1" ID="ID_1643809880" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_1423950960" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAD: 1.36-fold Down; FDR = 0.000605; PValue = 9.52e-05; mean CPM = 48.46; BCL2-associated agonist of cell death" ID="ID_664070878" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1417481357" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MDM2: 1.32-fold Up; FDR = 0.00555; PValue = 0.00119; mean CPM = 148.6; Uncharacterized protein" ID="ID_396196745" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_460920466" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP10: 1.81-fold Up; FDR = 0.0175; PValue = 0.0045; mean CPM = 2.876; caspase 10, apoptosis-related cysteine peptidase" ID="ID_896857074" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_129168985" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIE: 1.3-fold Down; FDR = 0.0272; PValue = 0.00752; mean CPM = 16.93; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon" ID="ID_1395964816" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRADD: 1.22-fold Up; FDR = 0.0319; PValue = 0.00907; mean CPM = 34.75; TNFRSF1A-associated via death domain" ID="ID_1078456999" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MCL1: 1.2-fold Up; FDR = 0.0335; PValue = 0.00961; mean CPM = 193.8; myeloid cell leukemia sequence 1 (BCL2-related)" ID="ID_212768275" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1079711740" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP63: 1.81-fold Down; FDR = 0.0567; PValue = 0.0179; mean CPM = 2.228; tumor protein p63" ID="ID_274673156" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP73: 2.3-fold Down; FDR = 0.0601; PValue = 0.0192; mean CPM = 1.058; tumor protein p73" ID="ID_1988272168" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L11: 1.34-fold Up; FDR = 0.0609; PValue = 0.0195; mean CPM = 18.38; BCL2-like 11 (apoptosis facilitator)" ID="ID_1635333797" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DFFA: 1.18-fold Down; FDR = 0.0688; PValue = 0.0225; mean CPM = 44.03; DNA fragmentation factor, 45kDa, alpha polypeptide" ID="ID_1073503355" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_280267612" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DIABLO: 1.17-fold Up; FDR = 0.0849; PValue = 0.0288; mean CPM = 58.69; diablo homolog (Drosophila)" ID="ID_277618281" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FADD: 1.18-fold Down; FDR = 0.0936; PValue = 0.0324; mean CPM = 30.89; Uncharacterized protein" ID="ID_1560885273" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_1769243758" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF4: 2.95-fold Down; FDR = 0.124; PValue = 0.0456; mean CPM = 0.9773; interferon regulatory factor 4" ID="ID_1466982544" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC5: 1.51-fold Down; FDR = 0.134; PValue = 0.0501; mean CPM = 18.55; Baculoviral IAP repeat-containing protein 5 isoform 1; Uncharacterized protein" ID="ID_1362410503" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_903647613" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XIAP: 1.17-fold Up; FDR = 0.177; PValue = 0.0706; mean CPM = 19.21; X-linked inhibitor of apoptosis" ID="ID_901922617" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP6: 1.17-fold Up; FDR = 0.197; PValue = 0.0807; mean CPM = 14.25; caspase 6, apoptosis-related cysteine peptidase" ID="ID_121004276" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP7: 1.15-fold Up; FDR = 0.218; PValue = 0.0916; mean CPM = 21.49; caspase 7, apoptosis-related cysteine peptidase" ID="ID_659165704" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000039103: 1.67-fold Down; FDR = 0.221; PValue = 0.0927; mean CPM = 1.310; Uncharacterized protein" ID="ID_1008965824" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1A: 1.11-fold Up; FDR = 0.297; PValue = 0.134; mean CPM = 134.7; tumor necrosis factor receptor superfamily, member 1A" ID="ID_247949375" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HELLS: 1.19-fold Down; FDR = 0.331; PValue = 0.153; mean CPM = 21.44; Uncharacterized protein" ID="ID_297069330" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF10B: 1.13-fold Down; FDR = 0.343; PValue = 0.16; mean CPM = 40.59; tumor necrosis factor receptor superfamily, member 10b" ID="ID_837137973" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP53: 1.11-fold Down; FDR = 0.364; PValue = 0.172; mean CPM = 33.25; tumor protein p53" ID="ID_1274692263" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF2: 1.42-fold Up; FDR = 0.383; PValue = 0.183; mean CPM = 31.20; insulin-like growth factor 2 (somatomedin A)" ID="ID_288293675" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2: 1.48-fold Up; FDR = 0.384; PValue = 0.184; mean CPM = 1.344; Uncharacterized protein" ID="ID_279892204" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BOK: 1.12-fold Down; FDR = 0.416; PValue = 0.204; mean CPM = 14.21; BCL2-related ovarian killer" ID="ID_297899307" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF6: 2.34-fold Down; FDR = 0.535; PValue = 0.283; mean CPM = 0.8609; interferon regulatory factor 6" ID="ID_842531921" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L2: 1.08-fold Down; FDR = 0.578; PValue = 0.314; mean CPM = 35.23; BCL2-like 2" ID="ID_1135785392" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF3: 1.07-fold Up; FDR = 0.611; PValue = 0.338; mean CPM = 34.56; TNF receptor-associated factor 3" ID="ID_1643640464" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_1408157752" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF25: 1.2-fold Up; FDR = 0.772; PValue = 0.471; mean CPM = 1.687; tumor necrosis factor receptor superfamily, member 25" ID="ID_23133490" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAX: 1.05-fold Up; FDR = 0.809; PValue = 0.506; mean CPM = 162.4; Uncharacterized protein" ID="ID_117984538" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRADD: 1.1-fold Down; FDR = 0.827; PValue = 0.527; mean CPM = 3.992; CASP2 and RIPK1 domain containing adaptor with death domain" ID="ID_1961513568" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GZMB: 1.43-fold Up; FDR = 0.83; PValue = 0.532; mean CPM = 0.7972; granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)" ID="ID_1144188588" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APAF1: 1.05-fold Down; FDR = 0.837; PValue = 0.543; mean CPM = 32.11; apoptotic peptidase activating factor 1" ID="ID_1311428382" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRF1: 1.75-fold Up; FDR = 0.841; PValue = 0.548; mean CPM = 0.8583; perforin 1 (pore forming protein)" ID="ID_1356261733" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF5: 1.06-fold Down; FDR = 0.85; PValue = 0.561; mean CPM = 9.280; interferon regulatory factor 5" ID="ID_463217100" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYCS: 1.05-fold Up; FDR = 0.854; PValue = 0.565; mean CPM = 93.43; cytochrome c, somatic" ID="ID_1814603252" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1291767025" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000040219: 1.08-fold Up; FDR = 0.86; PValue = 0.575; mean CPM = 8.818; Uncharacterized protein" ID="ID_720515781" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_1497491706" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP2: 1.05-fold Up; FDR = 0.906; PValue = 0.667; mean CPM = 12.88; caspase 2, apoptosis-related cysteine peptidase" ID="ID_1836424453" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DFFB: 1.05-fold Down; FDR = 0.911; PValue = 0.699; mean CPM = 5.555; DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)" ID="ID_836298860" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF21: 1.07-fold Down; FDR = 0.922; PValue = 0.726; mean CPM = 6.488; tumor necrosis factor receptor superfamily, member 21" ID="ID_920146101" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FASLG: 1.2-fold Down; FDR = 0.941; PValue = 0.757; mean CPM = 0.8088; Fas ligand (TNF superfamily, member 6)" ID="ID_1640019914" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BBC3: 1.04-fold Down; FDR = 0.948; PValue = 0.77; mean CPM = 7.586; BCL2 binding component 3" ID="ID_294424599" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000009289: 1.07-fold Up; FDR = 0.963; PValue = 0.798; mean CPM = 2.536; Uncharacterized protein" ID="ID_1409015372" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_1038761062" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP9: 1.01-fold Up; FDR = 1; PValue = 0.908; mean CPM = 19.86; caspase 9, apoptosis-related cysteine peptidase" ID="ID_310688389" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_709458288" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Striated Muscle Contraction (WP383:Rev45112): Downregulated, FDR = 0.512, PValue = 0.023" ID="ID_779782258" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="MYOM1: 6.65-fold Down; FDR = 1.7e-13; PValue = 2.34e-15; mean CPM = 107.5; myomesin 1" ID="ID_1909189282" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DMD: 2.29-fold Down; FDR = 6.37e-12; PValue = 1.28e-13; mean CPM = 17.66; Uncharacterized protein" ID="ID_1828578948" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYH3: 3.39-fold Down; FDR = 5.36e-09; PValue = 2.17e-10; mean CPM = 6.410; myosin, heavy chain 3, skeletal muscle, embryonic" ID="ID_1706315998" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TPM4: 1.8-fold Down; FDR = 1.34e-08; PValue = 5.96e-10; mean CPM = 1400; tropomyosin 4" ID="ID_429196279" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYL9: 2.18-fold Down; FDR = 2.17e-08; PValue = 1.03e-09; mean CPM = 805.4; myosin, light chain 9, regulatory" ID="ID_1030679965" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACTN4: 1.63-fold Down; FDR = 6.46e-08; PValue = 3.46e-09; mean CPM = 631.8; actinin, alpha 4" ID="ID_431033984" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DES: 9.53-fold Up; FDR = 7.57e-08; PValue = 4.1e-09; mean CPM = 59.19; desmin" ID="ID_1524063965" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYH8: 4.72-fold Down; FDR = 3.49e-06; PValue = 2.9e-07; mean CPM = 5.170; myosin, heavy chain 8, skeletal muscle, perinatal" ID="ID_1057952448" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYBPC3: 2.7-fold Down; FDR = 6.28e-06; PValue = 5.59e-07; mean CPM = 6.622; myosin binding protein C, cardiac" ID="ID_863848976" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TTN: 2.84-fold Down; FDR = 6.47e-06; PValue = 5.78e-07; mean CPM = 360.1; titin" ID="ID_1455846052" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMOD1: 3.73-fold Down; FDR = 6.41e-05; PValue = 7.52e-06; mean CPM = 1.614; tropomodulin 1" ID="ID_1223789338" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VIM: 1.54-fold Down; FDR = 0.000219; PValue = 3.01e-05; mean CPM = 3996; vimentin" ID="ID_152398363" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACTA1: 5.36-fold Down; FDR = 0.000251; PValue = 3.52e-05; mean CPM = 5.880; Uncharacterized protein" ID="ID_1286249270" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TCAP: 1.74-fold Down; FDR = 0.00819; PValue = 0.00187; mean CPM = 2.747; titin-cap (telethonin)" ID="ID_417350777" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNNT1: 1.52-fold Up; FDR = 0.00827; PValue = 0.00189; mean CPM = 12.30; troponin T type 1 (skeletal, slow)" ID="ID_1921880856" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNNI3: 1.94-fold Up; FDR = 0.0102; PValue = 0.0024; mean CPM = 2.886; Uncharacterized protein" ID="ID_789736500" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACTC1: 2.5-fold Down; FDR = 0.0968; PValue = 0.0338; mean CPM = 0.9546; actin, alpha, cardiac muscle 1" ID="ID_1308324952" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYBPC2: 2.05-fold Down; FDR = 0.115; PValue = 0.0414; mean CPM = 1.104; myosin binding protein C, fast type" ID="ID_1348020902" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNNC2: 1.59-fold Down; FDR = 0.175; PValue = 0.0696; mean CPM = 1.542; troponin C type 2 (fast)" ID="ID_1985507271" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNNT2: 1.64-fold Down; FDR = 0.24; PValue = 0.103; mean CPM = 1.443; troponin T type 2 (cardiac)" ID="ID_1580713633" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNNT3: 1.62-fold Down; FDR = 0.242; PValue = 0.104; mean CPM = 1.547; troponin T type 3 (skeletal, fast)" ID="ID_145227478" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYL3: 2-fold Down; FDR = 0.263; PValue = 0.115; mean CPM = 1.026; myosin, light chain 3, alkali; ventricular, skeletal, slow" ID="ID_1368013503" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TPM2: 1.85-fold Down; FDR = 0.59; PValue = 0.322; mean CPM = 0.8275; tropomyosin 2 (beta)" ID="ID_462563352" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYL4: 1.32-fold Down; FDR = 0.787; PValue = 0.484; mean CPM = 0.9677; myosin, light chain 4, alkali; atrial, embryonic" ID="ID_1722785161" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACTN2: 1.69-fold Down; FDR = 0.791; PValue = 0.488; mean CPM = 0.8357; actinin, alpha 2" ID="ID_843990967" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYL1: 1.65-fold Down; FDR = 0.81; PValue = 0.507; mean CPM = 0.8220; myosin, light chain 1, alkali; skeletal, fast" ID="ID_1374022937" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNNI2: 1.43-fold Down; FDR = 0.835; PValue = 0.538; mean CPM = 0.8240; Troponin I, fast-twitch isoform; Uncharacterized protein" ID="ID_274554688" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYL2: 1.15-fold Up; FDR = 0.909; PValue = 0.69; mean CPM = 0.7911; myosin, light chain 2, regulatory, cardiac, slow" ID="ID_306184962" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYH6: 1.11-fold Up; FDR = 0.975; PValue = 0.817; mean CPM = 1.001; myosin, heavy chain 6, cardiac muscle, alpha" ID="ID_1900876062" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNNC1: 1.03-fold Up; FDR = 1; PValue = 0.898; mean CPM = 11.38; troponin C type 1 (slow)" ID="ID_855634410" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Cholesterol Biosynthesis (WP197:Rev44991): Downregulated, FDR = 0.512, PValue = 0.0275" ID="ID_1025660068" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="DHCR7: 3.58-fold Down; FDR = 6.01e-13; PValue = 9.35e-15; mean CPM = 15.72; 7-dehydrocholesterol reductase" ID="ID_1624424124" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MVD: 2.35-fold Down; FDR = 8.85e-13; PValue = 1.42e-14; mean CPM = 18.63; mevalonate (diphospho) decarboxylase" ID="ID_586409031" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SREBF2: 2.26-fold Down; FDR = 4.11e-12; PValue = 7.71e-14; mean CPM = 92.78; sterol regulatory element binding transcription factor 2" ID="ID_591472221" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SQLE: 2.41-fold Down; FDR = 1.15e-07; PValue = 6.53e-09; mean CPM = 13.58; squalene epoxidase" ID="ID_1913483716" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MVK: 1.96-fold Down; FDR = 9.13e-07; PValue = 6.52e-08; mean CPM = 6.973; mevalonate kinase" ID="ID_407892278" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SC4MOL: 1.54-fold Down; FDR = 1.24e-05; PValue = 1.18e-06; mean CPM = 17.46; sterol-C4-methyl oxidase-like" ID="ID_1746387514" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LSS: 1.52-fold Down; FDR = 1.4e-05; PValue = 1.36e-06; mean CPM = 23.62; lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)" ID="ID_1352368492" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PMVK: 1.42-fold Down; FDR = 0.000723; PValue = 0.000117; mean CPM = 36.39; phosphomevalonate kinase" ID="ID_1912809286" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HMGCS1: 1.31-fold Down; FDR = 0.00578; PValue = 0.00125; mean CPM = 19.39; 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)" ID="ID_1396272468" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HMGCR: 1.25-fold Down; FDR = 0.00707; PValue = 0.00157; mean CPM = 46.64; 3-hydroxy-3-methylglutaryl-CoA reductase" ID="ID_1350312522" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYP51A1: 1.2-fold Down; FDR = 0.0512; PValue = 0.0158; mean CPM = 34.30; cytochrome P450, family 51, subfamily A, polypeptide 1" ID="ID_348077371" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FDPS: 1.15-fold Down; FDR = 0.126; PValue = 0.0464; mean CPM = 49.16; farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)" ID="ID_862020682" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SC5DL: 1.17-fold Up; FDR = 0.197; PValue = 0.0805; mean CPM = 23.20; sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like" ID="ID_1603671736" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SREBF1: 1.11-fold Down; FDR = 0.324; PValue = 0.149; mean CPM = 179.9; sterol regulatory element binding transcription factor 1" ID="ID_275971089" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FDFT1: 1.12-fold Up; FDR = 0.359; PValue = 0.169; mean CPM = 22.76; farnesyl-diphosphate farnesyltransferase 1" ID="ID_406319323" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NSDHL: 1.11-fold Down; FDR = 0.362; PValue = 0.171; mean CPM = 34.39; NAD(P) dependent steroid dehydrogenase-like" ID="ID_780884542" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IDI1: 1.1-fold Down; FDR = 0.525; PValue = 0.276; mean CPM = 20.34; isopentenyl-diphosphate delta isomerase 1" ID="ID_1643239796" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="AMPK signaling (WP1403:Rev44950): Downregulated, FDR = 0.512, PValue = 0.0288" ID="ID_1126105843" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="EEF2: 1.9-fold Down; FDR = 4.62e-10; PValue = 1.45e-11; mean CPM = 2932; eukaryotic translation elongation factor 2" ID="ID_489602432" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FASN: 2.14-fold Down; FDR = 1.36e-09; PValue = 4.74e-11; mean CPM = 192.4; fatty acid synthase" ID="ID_1812014906" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INSR: 1.93-fold Down; FDR = 1.24e-08; PValue = 5.48e-10; mean CPM = 118.3; insulin receptor" ID="ID_663036675" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EEF2K: 1.75-fold Down; FDR = 2.51e-08; PValue = 1.21e-09; mean CPM = 31.50; eukaryotic elongation factor-2 kinase" ID="ID_1849902047" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1186167088" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCB1: 1.71-fold Up; FDR = 1.31e-06; PValue = 9.73e-08; mean CPM = 34.36; phospholipase C, beta 1 (phosphoinositide-specific)" ID="ID_1849478524" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_907121058" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_1675617513" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKAA2: 1.7-fold Down; FDR = 5.6e-06; PValue = 4.89e-07; mean CPM = 11.23; protein kinase, AMP-activated, alpha 2 catalytic subunit" ID="ID_1844942407" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TSC2: 1.44-fold Down; FDR = 1e-05; PValue = 9.42e-07; mean CPM = 124.0; tuberous sclerosis 2" ID="ID_1147205463" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKAG2: 1.62-fold Down; FDR = 1.04e-05; PValue = 9.84e-07; mean CPM = 16.27; protein kinase, AMP-activated, gamma 2 non-catalytic subunit" ID="ID_96790288" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPTOR: 1.4-fold Down; FDR = 2.58e-05; PValue = 2.69e-06; mean CPM = 53.57; regulatory associated protein of MTOR, complex 1" ID="ID_519426027" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB2: 1.38-fold Down; FDR = 4.66e-05; PValue = 5.24e-06; mean CPM = 61.90; ribosomal protein S6 kinase, 70kDa, polypeptide 2" ID="ID_144600153" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAMKK1: 2.03-fold Down; FDR = 6.16e-05; PValue = 7.19e-06; mean CPM = 9.699; calcium/calmodulin-dependent protein kinase kinase 1, alpha" ID="ID_658820476" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKAA1: 1.32-fold Up; FDR = 0.000825; PValue = 0.000135; mean CPM = 40.69; protein kinase, AMP-activated, alpha 1 catalytic subunit" ID="ID_154414709" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STRADB: 1.42-fold Up; FDR = 0.000944; PValue = 0.000158; mean CPM = 14.01; STE20-related kinase adaptor beta" ID="ID_1617020594" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTOR: 1.3-fold Down; FDR = 0.00117; PValue = 0.000201; mean CPM = 107.5; mechanistic target of rapamycin (serine/threonine kinase)" ID="ID_1499972838" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPARGC1B: 1.57-fold Down; FDR = 0.00147; PValue = 0.000262; mean CPM = 8.323; peroxisome proliferator-activated receptor gamma, coactivator 1 beta" ID="ID_372249735" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACACA: 1.27-fold Down; FDR = 0.00395; PValue = 0.000809; mean CPM = 54.13; acetyl-CoA carboxylase alpha" ID="ID_524602897" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CPT1A: 1.38-fold Down; FDR = 0.00434; PValue = 0.000903; mean CPM = 110.4; carnitine palmitoyltransferase 1A (liver)" ID="ID_1377186477" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAMKK2: 1.27-fold Down; FDR = 0.00456; PValue = 0.000955; mean CPM = 37.99; calcium/calmodulin-dependent protein kinase kinase 2, beta" ID="ID_1193799806" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HMGCR: 1.25-fold Down; FDR = 0.00707; PValue = 0.00157; mean CPM = 46.64; 3-hydroxy-3-methylglutaryl-CoA reductase" ID="ID_1797468453" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CPT1C: 1.29-fold Down; FDR = 0.0155; PValue = 0.00391; mean CPM = 20.57; carnitine palmitoyltransferase 1C" ID="ID_210427036" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADIPOR2: 1.46-fold Down; FDR = 0.0179; PValue = 0.00461; mean CPM = 21.90; adiponectin receptor 2" ID="ID_967379313" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_671867715" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LEP: 1.67-fold Down; FDR = 0.0401; PValue = 0.0118; mean CPM = 63.70; leptin" ID="ID_623456138" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TSC1: 1.19-fold Down; FDR = 0.0564; PValue = 0.0177; mean CPM = 38.34; tuberous sclerosis 1" ID="ID_1922370792" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LIPE: 1.27-fold Down; FDR = 0.0669; PValue = 0.0217; mean CPM = 9.982; lipase, hormone-sensitive" ID="ID_958680319" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF4EBP1: 1.23-fold Up; FDR = 0.0729; PValue = 0.0241; mean CPM = 40.55; eukaryotic translation initiation factor 4E binding protein 1" ID="ID_460565023" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNB1: 1.39-fold Down; FDR = 0.0958; PValue = 0.0333; mean CPM = 44.87; cyclin B1" ID="ID_333197322" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRTC2: 1.18-fold Up; FDR = 0.0976; PValue = 0.0341; mean CPM = 27.36; CREB regulated transcription coactivator 2" ID="ID_1184287537" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ELAVL1: 1.13-fold Down; FDR = 0.206; PValue = 0.085; mean CPM = 53.94; ELAV-like protein 1; Uncharacterized protein" ID="ID_32049866" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1A: 1.16-fold Down; FDR = 0.28; PValue = 0.124; mean CPM = 363.2; Cyclin-dependent kinase inhibitor 1; Uncharacterized protein" ID="ID_128142314" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC2A4RG: 1.14-fold Up; FDR = 0.296; PValue = 0.133; mean CPM = 17.77; SLC2A4 regulator" ID="ID_613486923" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKAB1: 1.12-fold Up; FDR = 0.3; PValue = 0.136; mean CPM = 30.19; protein kinase, AMP-activated, beta 1 non-catalytic subunit" ID="ID_136219113" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SREBF1: 1.11-fold Down; FDR = 0.324; PValue = 0.149; mean CPM = 179.9; sterol regulatory element binding transcription factor 1" ID="ID_163075028" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_1849894536" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP53: 1.11-fold Down; FDR = 0.364; PValue = 0.172; mean CPM = 33.25; tumor protein p53" ID="ID_52002297" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKAG1: 1.1-fold Up; FDR = 0.365; PValue = 0.173; mean CPM = 52.15; Uncharacterized protein" ID="ID_1826339104" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAB39: 1.11-fold Up; FDR = 0.371; PValue = 0.176; mean CPM = 33.59; calcium binding protein 39" ID="ID_1158983838" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_597843023" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GYS1: 1.1-fold Down; FDR = 0.405; PValue = 0.197; mean CPM = 143.6; glycogen synthase 1 (muscle)" ID="ID_864620148" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNA2: 1.24-fold Down; FDR = 0.441; PValue = 0.22; mean CPM = 24.05; cyclin A2" ID="ID_1016888207" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LEPR: 1.52-fold Down; FDR = 0.489; PValue = 0.251; mean CPM = 1.051; leptin receptor" ID="ID_591016160" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AC002126.5: 1.1-fold Down; FDR = 0.495; PValue = 0.255; mean CPM = 18.66; UPF0402 protein" ID="ID_920654338" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADRA1B: 1.31-fold Down; FDR = 0.506; PValue = 0.262; mean CPM = 1.799; adrenergic, alpha-1B-, receptor" ID="ID_1381772901" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADIPOR1: 1.06-fold Up; FDR = 0.694; PValue = 0.402; mean CPM = 101.7; adiponectin receptor 1" ID="ID_1693732851" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADIPOQ: 1.98-fold Down; FDR = 0.729; PValue = 0.431; mean CPM = 0.8241; adiponectin, C1Q and collagen domain containing" ID="ID_1808815040" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACG: 1.51-fold Down; FDR = 0.795; PValue = 0.491; mean CPM = 0.8026; protein kinase, cAMP-dependent, catalytic, gamma" ID="ID_1099314703" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKAB2: 1.07-fold Down; FDR = 0.809; PValue = 0.505; mean CPM = 10.04; protein kinase, AMP-activated, beta 2 non-catalytic subunit" ID="ID_1184138497" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB1: 1.04-fold Up; FDR = 0.88; PValue = 0.6; mean CPM = 30.80; Uncharacterized protein" ID="ID_1836031601" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STRADA: 1.04-fold Down; FDR = 0.883; PValue = 0.604; mean CPM = 18.06; STE20-related kinase adaptor alpha" ID="ID_1164291113" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACB: 1.03-fold Up; FDR = 0.911; PValue = 0.694; mean CPM = 30.10; protein kinase, cAMP-dependent, catalytic, beta" ID="ID_1507755709" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INS: 1.11-fold Up; FDR = 0.914; PValue = 0.712; mean CPM = 0.7930; insulin" ID="ID_1567080934" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CPT1B: 1.05-fold Up; FDR = 0.923; PValue = 0.728; mean CPM = 5.764; carnitine palmitoyltransferase 1B (muscle)" ID="ID_1497283318" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNA1: 1.28-fold Down; FDR = 0.928; PValue = 0.736; mean CPM = 0.8658; cyclin A1" ID="ID_240892062" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADRA1A: 1.25-fold Up; FDR = 0.942; PValue = 0.76; mean CPM = 0.8073; Macaca mulatta adrenergic, alpha-1A-, receptor (ADRA1A), mRNA." ID="ID_310754395" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STK11: 1.01-fold Up; FDR = 1; PValue = 0.918; mean CPM = 47.98; serine/threonine kinase 11" ID="ID_1070157177" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GYS2: 1.01-fold Down; FDR = 1; PValue = 0.983; mean CPM = 0.7991; glycogen synthase 2 (liver)" ID="ID_505643269" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-7 signaling pathway (WP205:Rev45369): Upregulated, FDR = 0.512, PValue = 0.0297" ID="ID_555797972" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_253437473" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5A: 2.28-fold Up; FDR = 6.87e-14; PValue = 8.58e-16; mean CPM = 21.55; signal transducer and activator of transcription 5A" ID="ID_1439784448" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL7: 9.03-fold Up; FDR = 1.39e-13; PValue = 1.9e-15; mean CPM = 5.288; interleukin 7" ID="ID_1042836230" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_673557893" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1B: 1.64-fold Up; FDR = 1.22e-08; PValue = 5.39e-10; mean CPM = 32.96; Cyclin-dependent kinase inhibitor 1B; Uncharacterized protein" ID="ID_1705760874" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2B: 3.54-fold Up; FDR = 1.24e-07; PValue = 7.07e-09; mean CPM = 5.971; PTK2B protein tyrosine kinase 2 beta" ID="ID_1941592988" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_721230138" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L1: 1.51-fold Up; FDR = 9.13e-07; PValue = 6.52e-08; mean CPM = 66.15; Bcl-2-like protein 1; Bcl-2-like protein 1 isoform 1; Uncharacterized protein" ID="ID_1750079059" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_692570531" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1584897874" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAD: 1.36-fold Down; FDR = 0.000605; PValue = 9.52e-05; mean CPM = 48.46; BCL2-associated agonist of cell death" ID="ID_1929422073" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK3: 2.31-fold Up; FDR = 0.00186; PValue = 0.000342; mean CPM = 2.154; Janus kinase 3" ID="ID_839221993" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FYN: 1.22-fold Up; FDR = 0.0156; PValue = 0.00393; mean CPM = 92.94; FYN oncogene related to SRC, FGR, YES" ID="ID_1799261278" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_106223798" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_288269844" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_1313112240" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL7R: 1.76-fold Down; FDR = 0.0698; PValue = 0.0229; mean CPM = 3.067; interleukin 7 receptor" ID="ID_843864198" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_293463094" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND1: 1.17-fold Up; FDR = 0.121; PValue = 0.0443; mean CPM = 867.3; cyclin D1" ID="ID_733211737" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_41580587" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1838757293" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_843152384" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2RA: 1.08-fold Up; FDR = 0.945; PValue = 0.766; mean CPM = 0.8493; interleukin 2 receptor, alpha" ID="ID_1023282996" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Matrix Metalloproteinases (WP129:Rev44892): Downregulated, FDR = 0.512, PValue = 0.0303" ID="ID_1820811504" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="MMP14: 1.69-fold Down; FDR = 6e-09; PValue = 2.46e-10; mean CPM = 390.7; matrix metallopeptidase 14 (membrane-inserted)" ID="ID_746010754" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TIMP2: 1.66-fold Down; FDR = 1.39e-07; PValue = 8e-09; mean CPM = 138.5; TIMP metallopeptidase inhibitor 2" ID="ID_1331547537" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP17: 2.85-fold Down; FDR = 4.1e-07; PValue = 2.67e-08; mean CPM = 5.440; matrix metallopeptidase 17 (membrane-inserted)" ID="ID_300488050" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP23B: 3.52-fold Down; FDR = 9.11e-07; PValue = 6.49e-08; mean CPM = 3.818; matrix metallopeptidase 23B" ID="ID_599685956" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP16: 1.93-fold Down; FDR = 6.34e-06; PValue = 5.64e-07; mean CPM = 13.80; matrix metallopeptidase 16 (membrane-inserted)" ID="ID_1984732635" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP11: 2.57-fold Down; FDR = 3.12e-05; PValue = 3.32e-06; mean CPM = 36.98; matrix metallopeptidase 11 (stromelysin 3)" ID="ID_526423841" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP10: 4.95-fold Down; FDR = 4.35e-05; PValue = 4.84e-06; mean CPM = 6.712; matrix metallopeptidase 10 (stromelysin 2)" ID="ID_726321489" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BSG: 1.3-fold Down; FDR = 0.00161; PValue = 0.00029; mean CPM = 272.4; basigin (Ok blood group)" ID="ID_1548741117" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP28: 1.9-fold Down; FDR = 0.0021; PValue = 0.000391; mean CPM = 3.380; matrix metallopeptidase 28" ID="ID_1895122450" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP9: 4.49-fold Down; FDR = 0.00222; PValue = 0.000419; mean CPM = 6.597; matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)" ID="ID_1585306516" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP1: 3.27-fold Down; FDR = 0.00611; PValue = 0.00133; mean CPM = 110.4; matrix metallopeptidase 1 (interstitial collagenase)" ID="ID_533701126" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP3: 3.29-fold Down; FDR = 0.104; PValue = 0.037; mean CPM = 81.12; matrix metallopeptidase 3 (stromelysin 1, progelatinase)" ID="ID_44662858" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP24: 1.9-fold Down; FDR = 0.123; PValue = 0.045; mean CPM = 1.742; matrix metallopeptidase 24 (membrane-inserted)" ID="ID_470119188" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP19: 1.25-fold Down; FDR = 0.131; PValue = 0.0488; mean CPM = 10.93; matrix metallopeptidase 19" ID="ID_771921283" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP21: 1.25-fold Down; FDR = 0.683; PValue = 0.393; mean CPM = 1.578; matrix metallopeptidase 21" ID="ID_1762219916" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP8: 1.48-fold Up; FDR = 0.814; PValue = 0.511; mean CPM = 0.8081; matrix metallopeptidase 8 (neutrophil collagenase)" ID="ID_1896410194" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TCF20: 1.04-fold Up; FDR = 0.888; PValue = 0.611; mean CPM = 90.07; transcription factor 20 (AR1)" ID="ID_1041641843" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_1983351648" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP7: 1.39-fold Down; FDR = 0.89; PValue = 0.613; mean CPM = 0.8356; Uncharacterized protein" ID="ID_1558161243" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP15: 1.08-fold Up; FDR = 0.897; PValue = 0.622; mean CPM = 7.415; matrix metallopeptidase 15 (membrane-inserted)" ID="ID_1213296672" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP27: 1.21-fold Up; FDR = 0.919; PValue = 0.72; mean CPM = 0.8172; matrix metallopeptidase 27" ID="ID_1546926434" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP25: 1.24-fold Up; FDR = 0.939; PValue = 0.753; mean CPM = 0.8461; matrix metallopeptidase 25" ID="ID_1088055825" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP20: 1.04-fold Down; FDR = 1; PValue = 0.947; mean CPM = 0.8723; matrix metallopeptidase 20" ID="ID_892463630" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP2: No Change; FDR = 1; PValue = 0.976; mean CPM = 210.3; matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)" ID="ID_136627125" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP26: No Change; FDR = 1; PValue = 0.998; mean CPM = 0.8086; matrix metallopeptidase 26" ID="ID_155446452" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Inflammatory Response Pathway (WP453:Rev41201): Downregulated, FDR = 0.512, PValue = 0.032" ID="ID_1852156056" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="COL3A1: 20.5-fold Down; FDR = 5.71e-15; PValue = 5.82e-17; mean CPM = 5961; collagen, type III, alpha 1" ID="ID_1717790671" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL1A1: 21.5-fold Down; FDR = 1.13e-13; PValue = 1.5e-15; mean CPM = 15389; collagen, type I, alpha 1" ID="ID_1095816286" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL1A2: 10.7-fold Down; FDR = 3.82e-13; PValue = 5.68e-15; mean CPM = 17923; collagen, type I, alpha 2" ID="ID_290739051" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMC1: 2.28-fold Down; FDR = 6.46e-13; PValue = 1.01e-14; mean CPM = 812.1; laminin, gamma 1 (formerly LAMB2)" ID="ID_1520418127" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016591: 4.2-fold Down; FDR = 1.3e-11; PValue = 2.78e-13; mean CPM = 34.90; Uncharacterized protein" ID="ID_611003693" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016587: 4.92-fold Down; FDR = 1.6e-11; PValue = 3.5e-13; mean CPM = 51.70; Uncharacterized protein" ID="ID_1290895461" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THBS3: 1.97-fold Up; FDR = 7.19e-08; PValue = 3.88e-09; mean CPM = 128.6; thrombospondin 3" ID="ID_1660545434" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THBS1: 2.74-fold Down; FDR = 1.68e-06; PValue = 1.28e-07; mean CPM = 25785; thrombospondin 1" ID="ID_521236112" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1B: 2.24-fold Up; FDR = 2.68e-06; PValue = 2.16e-07; mean CPM = 19.44; tumor necrosis factor receptor superfamily, member 1B" ID="ID_1365881717" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMC2: 2.28-fold Down; FDR = 9.83e-06; PValue = 9.24e-07; mean CPM = 16.99; laminin, gamma 2" ID="ID_1133600090" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40: 2.76-fold Up; FDR = 0.00039; PValue = 5.79e-05; mean CPM = 9.139; CD40 molecule, TNF receptor superfamily member 5" ID="ID_997337131" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB2: 1.48-fold Down; FDR = 0.000398; PValue = 5.93e-05; mean CPM = 695.6; laminin, beta 2 (laminin S)" ID="ID_265384171" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FN1: 1.7-fold Down; FDR = 0.0164; PValue = 0.00417; mean CPM = 40317; fibronectin 1" ID="ID_972774241" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1A: 1.11-fold Up; FDR = 0.297; PValue = 0.134; mean CPM = 134.7; tumor necrosis factor receptor superfamily, member 1A" ID="ID_1050403291" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VTN: 1.19-fold Up; FDR = 0.669; PValue = 0.382; mean CPM = 2.950; vitronectin" ID="ID_1208142807" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL4R: 1.05-fold Down; FDR = 0.803; PValue = 0.499; mean CPM = 193.5; interleukin 4 receptor" ID="ID_1018785539" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZAP70: 1.25-fold Down; FDR = 0.872; PValue = 0.59; mean CPM = 0.8996; zeta-chain (TCR) associated protein kinase 70kDa" ID="ID_114467054" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_590094854" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL4: 1.27-fold Down; FDR = 0.933; PValue = 0.745; mean CPM = 0.8077; interleukin 4" ID="ID_1526680145" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2RA: 1.08-fold Up; FDR = 0.945; PValue = 0.766; mean CPM = 0.8493; interleukin 2 receptor, alpha" ID="ID_1666020613" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL5RA: 1.1-fold Up; FDR = 0.958; PValue = 0.791; mean CPM = 0.8108; interleukin 5 receptor, alpha" ID="ID_122190411" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD80: 1.08-fold Up; FDR = 0.971; PValue = 0.812; mean CPM = 1.157; CD80 molecule" ID="ID_1735735170" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL5: 1.05-fold Down; FDR = 1; PValue = 0.862; mean CPM = 1.367; interleukin 5 (colony-stimulating factor, eosinophil)" ID="ID_250894790" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40LG: 1.01-fold Down; FDR = 1; PValue = 0.982; mean CPM = 0.8653; CD40 ligand" ID="ID_130446317" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD86: 1.01-fold Down; FDR = 1; PValue = 0.99; mean CPM = 0.8012; CD86 molecule" ID="ID_202085888" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2: 1.03-fold Up; FDR = 1; PValue = 0.998; mean CPM = 0.7974; interleukin 2" ID="ID_1183481071" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Serotonin Receptor 2 and STAT3 Signaling (WP733:Rev45035): Upregulated, FDR = 0.575, PValue = 0.0461" ID="ID_1378836345" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_542456767" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_354865637" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HTR2A: 1.18-fold Up; FDR = 0.253; PValue = 0.11; mean CPM = 70.26; 5-hydroxytryptamine (serotonin) receptor 2A" ID="ID_1545889080" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAQ: 1.05-fold Down; FDR = 0.889; PValue = 0.611; mean CPM = 9.623; Guanine nucleotide-binding protein G(Q) subunit alpha; Uncharacterized protein" ID="ID_1307108873" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAQ: No Change; FDR = 1; PValue = 0.975; mean CPM = 15.20; guanine nucleotide binding protein (G protein), q polypeptide" ID="ID_1805426106" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-6 signaling pathway (WP364:Rev44848): Upregulated, FDR = 0.575, PValue = 0.0465" ID="ID_1599449369" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="IRF1: 18.6-fold Up; FDR = 1.53e-21; PValue = 4.24e-24; mean CPM = 240.7; interferon regulatory factor 1" ID="ID_797151748" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_103168088" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_518103958" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_1935500323" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_698242344" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL6ST: 1.78-fold Up; FDR = 1.86e-08; PValue = 8.65e-10; mean CPM = 437.6; interleukin 6 signal transducer (gp130, oncostatin M receptor)" ID="ID_1792627445" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRDM1: 3.05-fold Up; FDR = 3.55e-08; PValue = 1.78e-09; mean CPM = 8.715; PR domain containing 1, with ZNF domain" ID="ID_150834193" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_651352527" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L1: 1.51-fold Up; FDR = 9.13e-07; PValue = 6.52e-08; mean CPM = 66.15; Bcl-2-like protein 1; Bcl-2-like protein 1 isoform 1; Uncharacterized protein" ID="ID_1892691252" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1888597006" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL6R: 3.84-fold Down; FDR = 6.68e-05; PValue = 7.89e-06; mean CPM = 4.840; interleukin 6 receptor" ID="ID_827335771" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAD: 1.36-fold Down; FDR = 0.000605; PValue = 9.52e-05; mean CPM = 48.46; BCL2-associated agonist of cell death" ID="ID_1669964836" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS3: 1.69-fold Up; FDR = 0.000994; PValue = 0.000167; mean CPM = 37.76; suppressor of cytokine signaling 3" ID="ID_1147099977" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYK2: 1.24-fold Down; FDR = 0.0142; PValue = 0.00354; mean CPM = 42.58; tyrosine kinase 2" ID="ID_1784476565" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC1: 1.25-fold Up; FDR = 0.0159; PValue = 0.00403; mean CPM = 27.51; histone deacetylase 1" ID="ID_1631943121" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1545324372" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1853917049" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_356478001" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCOA1: 1.18-fold Up; FDR = 0.112; PValue = 0.04; mean CPM = 20.42; nuclear receptor coactivator 1" ID="ID_1210423449" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_241092746" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="A2M: 1.33-fold Up; FDR = 0.181; PValue = 0.0726; mean CPM = 750.0; alpha-2-macroglobulin" ID="ID_1559815392" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1857563706" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_1502500959" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_333233209" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_870148167" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCD: 1.06-fold Up; FDR = 0.696; PValue = 0.404; mean CPM = 37.45; protein kinase C, delta" ID="ID_715775252" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HCK: 1.3-fold Down; FDR = 0.797; PValue = 0.494; mean CPM = 0.9272; Uncharacterized protein" ID="ID_342931882" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV1: 1.25-fold Down; FDR = 0.858; PValue = 0.572; mean CPM = 0.9515; vav 1 guanine nucleotide exchange factor" ID="ID_556051977" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_254051874" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB1: 1.04-fold Up; FDR = 0.88; PValue = 0.6; mean CPM = 30.80; Uncharacterized protein" ID="ID_1738376778" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_1927896411" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREBBP: 1.01-fold Down; FDR = 0.993; PValue = 0.847; mean CPM = 137.7; CREB binding protein" ID="ID_487728257" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_622740841" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLK: No Change; FDR = 1; PValue = 0.97; mean CPM = 11.78; nemo-like kinase" ID="ID_540952302" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AGT: 1.02-fold Down; FDR = 1; PValue = 0.996; mean CPM = 0.8004; angiotensinogen (serpin peptidase inhibitor, clade A, member 8)" ID="ID_45807739" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRP: No Change; FDR = 1; PValue = 1; mean CPM = 0.7818; Uncharacterized protein" ID="ID_1320724885" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Toll-like receptor signaling pathway (WP75:Rev45082): Upregulated, FDR = 0.575, PValue = 0.0484" ID="ID_1370535875" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TLR2: 8.94-fold Up; FDR = 6.97e-23; PValue = 1.25e-25; mean CPM = 18.41; toll-like receptor 2" ID="ID_907460562" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL10: 462-fold Up; FDR = 1.01e-21; PValue = 2.65e-24; mean CPM = 286.2; Macaca mulatta chemokine (C-X-C motif) ligand 10 (CXCL10), mRNA." ID="ID_621355105" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR3: 10.3-fold Up; FDR = 1.95e-21; PValue = 5.6e-24; mean CPM = 35.70; toll-like receptor 3" ID="ID_803697422" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL11: 256-fold Up; FDR = 1e-19; PValue = 3.96e-22; mean CPM = 84.82; chemokine (C-X-C motif) ligand 11" ID="ID_751987389" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL9: 345-fold Up; FDR = 4.16e-19; PValue = 1.97e-21; mean CPM = 175.7; Macaca mulatta chemokine (C-X-C motif) ligand 9 (CXCL9), mRNA." ID="ID_1438402197" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1399136036" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF7: 14.8-fold Up; FDR = 7.66e-18; PValue = 4.82e-20; mean CPM = 11.54; Macaca mulatta interferon regulatory factor 7 (IRF7), mRNA." ID="ID_205360656" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_1966301992" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LY96: 3.13-fold Up; FDR = 1.27e-10; PValue = 3.43e-12; mean CPM = 6.127; lymphocyte antigen 96" ID="ID_1297144572" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR4: 3.45-fold Up; FDR = 3.1e-09; PValue = 1.19e-10; mean CPM = 7.456; Macaca mulatta toll-like receptor 4 (TLR4), mRNA." ID="ID_1782110899" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_1488539107" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK4: 1.8-fold Up; FDR = 3.31e-08; PValue = 1.64e-09; mean CPM = 12.89; interleukin-1 receptor-associated kinase 4" ID="ID_308791127" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1643500970" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL5: 6.74-fold Up; FDR = 2.65e-07; PValue = 1.64e-08; mean CPM = 30.35; chemokine (C-C motif) ligand 5" ID="ID_856030386" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_367458854" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD14: 2.75-fold Down; FDR = 6.54e-07; PValue = 4.46e-08; mean CPM = 5.195; CD14 molecule" ID="ID_1946421829" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1604588619" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_1328320876" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR2: 1.74-fold Up; FDR = 1.85e-06; PValue = 1.44e-07; mean CPM = 26.05; interferon (alpha, beta and omega) receptor 2" ID="ID_1392949948" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_584038703" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K3: 1.45-fold Down; FDR = 7.01e-06; PValue = 6.34e-07; mean CPM = 180.1; mitogen-activated protein kinase kinase 3" ID="ID_958476351" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_898308932" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPP1: 2.25-fold Down; FDR = 7.74e-05; PValue = 9.29e-06; mean CPM = 35.33; secreted phosphoprotein 1" ID="ID_1390371173" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_1255785223" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP2: 1.45-fold Up; FDR = 0.000179; PValue = 2.4e-05; mean CPM = 65.31; TGF-beta activated kinase 1/MAP3K7 binding protein 2" ID="ID_70097183" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40: 2.76-fold Up; FDR = 0.00039; PValue = 5.79e-05; mean CPM = 9.139; CD40 molecule, TNF receptor superfamily member 5" ID="ID_1444396376" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TOLLIP: 1.36-fold Down; FDR = 0.000551; PValue = 8.57e-05; mean CPM = 28.79; Uncharacterized protein" ID="ID_286024837" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBK1: 1.3-fold Up; FDR = 0.00337; PValue = 0.000674; mean CPM = 30.46; TANK-binding kinase 1" ID="ID_969180733" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1546953130" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_343667206" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR5: 1.86-fold Down; FDR = 0.00878; PValue = 0.00203; mean CPM = 3.008; toll-like receptor 5" ID="ID_899388105" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12A: 2.09-fold Up; FDR = 0.00924; PValue = 0.00215; mean CPM = 2.872; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)" ID="ID_1496552864" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR1: 1.27-fold Up; FDR = 0.0101; PValue = 0.00237; mean CPM = 82.39; Uncharacterized protein" ID="ID_187605689" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1515997768" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL8: 2.33-fold Up; FDR = 0.0209; PValue = 0.00552; mean CPM = 2326; interleukin 8" ID="ID_1936197955" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1465589909" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_1639889508" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1464672318" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL3: 2.04-fold Down; FDR = 0.067; PValue = 0.0218; mean CPM = 3.575; chemokine (C-C motif) ligand 3" ID="ID_326260577" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K8: 1.35-fold Down; FDR = 0.0831; PValue = 0.0281; mean CPM = 8.912; mitogen-activated protein kinase kinase kinase 8" ID="ID_16277070" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FADD: 1.18-fold Down; FDR = 0.0936; PValue = 0.0324; mean CPM = 30.89; Uncharacterized protein" ID="ID_735518316" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_469326970" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_52075293" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_729192314" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_618319136" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_954425751" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP1: 1.12-fold Down; FDR = 0.351; PValue = 0.165; mean CPM = 17.96; TGF-beta activated kinase 1/MAP3K7 binding protein 1" ID="ID_1260252227" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1806896064" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TICAM1: 1.11-fold Down; FDR = 0.398; PValue = 0.192; mean CPM = 26.73; toll-like receptor adaptor molecule 1" ID="ID_1191198623" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_591330627" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_397459560" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK12: 1.19-fold Down; FDR = 0.422; PValue = 0.208; mean CPM = 6.569; mitogen-activated protein kinase 12" ID="ID_597314249" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1803041510" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_548561020" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK13: 1.22-fold Down; FDR = 0.536; PValue = 0.284; mean CPM = 3.100; mitogen-activated protein kinase 13" ID="ID_1870968419" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LBP: 1.52-fold Down; FDR = 0.591; PValue = 0.324; mean CPM = 0.8819; lipopolysaccharide binding protein" ID="ID_1152765181" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF3: 1.07-fold Up; FDR = 0.611; PValue = 0.338; mean CPM = 34.56; TNF receptor-associated factor 3" ID="ID_561396116" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_925095218" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNB1: 1.79-fold Up; FDR = 0.731; PValue = 0.433; mean CPM = 0.8526; interferon, beta 1, fibroblast" ID="ID_1819935691" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMED7-TICAM2: 1.05-fold Down; FDR = 0.796; PValue = 0.493; mean CPM = 150.6; TMED7-TICAM2 readthrough" ID="ID_573298002" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA6: 1.41-fold Down; FDR = 0.807; PValue = 0.504; mean CPM = 0.8019; interferon, alpha 6" ID="ID_199618943" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR6: 1.07-fold Down; FDR = 0.84; PValue = 0.546; mean CPM = 7.909; toll-like receptor 6" ID="ID_775694487" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TIRAP: 1.07-fold Up; FDR = 0.841; PValue = 0.548; mean CPM = 8.693; Macaca mulatta toll-interleukin 1 receptor (TIR) domain containing adaptor protein (TIRAP), mRNA." ID="ID_1117690263" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF5: 1.06-fold Down; FDR = 0.85; PValue = 0.561; mean CPM = 9.280; interferon regulatory factor 5" ID="ID_1559989259" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1890895487" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_74753748" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR7: 1.37-fold Down; FDR = 0.878; PValue = 0.597; mean CPM = 0.8402; toll-like receptor 7" ID="ID_1707355727" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK1: 1.04-fold Down; FDR = 0.885; PValue = 0.606; mean CPM = 41.54; interleukin-1 receptor-associated kinase 1" ID="ID_801449567" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_1868763181" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA13: 1.13-fold Up; FDR = 0.908; PValue = 0.677; mean CPM = 0.7960; interferon, alpha 13" ID="ID_1302511212" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA8: 1.13-fold Down; FDR = 0.911; PValue = 0.702; mean CPM = 0.7910; interferon, alpha 8" ID="ID_405730790" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKE: 1.03-fold Up; FDR = 0.929; PValue = 0.737; mean CPM = 21.61; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon" ID="ID_1659718013" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA14: 1.22-fold Up; FDR = 0.965; PValue = 0.802; mean CPM = 0.8654; interferon, alpha 14" ID="ID_1584349338" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_1151698593" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD80: 1.08-fold Up; FDR = 0.971; PValue = 0.812; mean CPM = 1.157; CD80 molecule" ID="ID_522035088" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_666636716" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA4: 1.28-fold Down; FDR = 0.983; PValue = 0.829; mean CPM = 0.8584; interferon, alpha 4" ID="ID_1198066534" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12B: 1.07-fold Up; FDR = 0.983; PValue = 0.831; mean CPM = 0.8197; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)" ID="ID_1075158709" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_1293204739" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR9: 1.01-fold Down; FDR = 1; PValue = 0.859; mean CPM = 21.45; Macaca mulatta toll-like receptor 9 (TLR9), mRNA." ID="ID_1907893856" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR1: 1.02-fold Up; FDR = 1; PValue = 0.945; mean CPM = 1.221; toll-like receptor 1" ID="ID_1985674412" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD86: 1.01-fold Down; FDR = 1; PValue = 0.99; mean CPM = 0.8012; CD86 molecule" ID="ID_1018096768" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA1: No Change; FDR = 1; PValue = 0.998; mean CPM = 0.8014; interferon, alpha 1" ID="ID_945964315" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- </node>
- <node TEXT="globaltest gene set test" ID="ID_62465321" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="Type II interferon signaling (IFNG) (WP619:Rev45027): FDR = 7.35e-28, PValue = 3.83e-30" ID="ID_1583198225" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TAP1: 8.86-fold Up; FDR = 4.25e-27; PValue = 3.99e-31; mean CPM = 524.4; Antigen peptide transporter 1 (APT1)(Peptide transporter TAP1)(ATP-binding cassette sub-family B member 2)(Peptide supply factor 1)(Peptide transporter PSF1)(PSF-1)(Peptide transporter involved in antigen processing 1)(Really interesting new gene 4 /.../n)" ID="ID_1227292957" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GBP1: 54.9-fold Up; FDR = 3.11e-24; PValue = 2.93e-27; mean CPM = 1282; guanylate binding protein 1, interferon-inducible, 67kDa" ID="ID_924949080" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMB9: 18.6-fold Up; FDR = 5.15e-24; PValue = 5.86e-27; mean CPM = 380.3; proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)" ID="ID_45334389" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFI6: 19-fold Up; FDR = 6.4e-22; PValue = 1.59e-24; mean CPM = 1370; interferon, alpha-inducible protein 6" ID="ID_1712209505" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFIT2: 80.8-fold Up; FDR = 9.69e-22; PValue = 2.5e-24; mean CPM = 473.4; interferon-induced protein with tetratricopeptide repeats 2" ID="ID_522685495" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL10: 462-fold Up; FDR = 1.01e-21; PValue = 2.65e-24; mean CPM = 286.2; Macaca mulatta chemokine (C-X-C motif) ligand 10 (CXCL10), mRNA." ID="ID_1980142706" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000027180: 6.97-fold Up; FDR = 1.24e-21; PValue = 3.39e-24; mean CPM = 285.4; Uncharacterized protein" ID="ID_1543579551" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF1: 18.6-fold Up; FDR = 1.53e-21; PValue = 4.24e-24; mean CPM = 240.7; interferon regulatory factor 1" ID="ID_1546451646" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000005183: 4.07-fold Up; FDR = 2.87e-21; PValue = 8.51e-24; mean CPM = 164.7; Uncharacterized protein" ID="ID_1990847042" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="OAS1: 41-fold Up; FDR = 1.01e-20; PValue = 3.28e-23; mean CPM = 37.38; Macaca mulatta 2',5'-oligoadenylate synthetase 1, 40/46kDa (OAS1), mRNA." ID="ID_95994045" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF9: 3.85-fold Up; FDR = 2.6e-19; PValue = 1.12e-21; mean CPM = 106.4; interferon regulatory factor 9" ID="ID_1050822033" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL9: 345-fold Up; FDR = 4.16e-19; PValue = 1.97e-21; mean CPM = 175.7; Macaca mulatta chemokine (C-X-C motif) ligand 9 (CXCL9), mRNA." ID="ID_1117688986" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT2: 2.67-fold Up; FDR = 8.02e-19; PValue = 4.03e-21; mean CPM = 185.6; signal transducer and activator of transcription 2, 113kDa" ID="ID_927263056" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_800495961" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_67822974" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF2: 3.25-fold Up; FDR = 2.61e-18; PValue = 1.48e-20; mean CPM = 32.37; interferon regulatory factor 2" ID="ID_724183561" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2AK2: 3.01-fold Up; FDR = 6.08e-18; PValue = 3.74e-20; mean CPM = 47.85; eukaryotic translation initiation factor 2-alpha kinase 2" ID="ID_888968134" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CIITA: 45.8-fold Up; FDR = 1.14e-17; PValue = 7.44e-20; mean CPM = 27.80; class II, major histocompatibility complex, transactivator" ID="ID_274612934" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICAM1: 24.6-fold Up; FDR = 2.39e-17; PValue = 1.64e-19; mean CPM = 232.4; intercellular adhesion molecule 1" ID="ID_1541168690" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ISG15: 15.5-fold Up; FDR = 2.16e-15; PValue = 2.02e-17; mean CPM = 55.60; ISG15 ubiquitin-like modifier" ID="ID_189421251" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF8: 11.4-fold Up; FDR = 6e-09; PValue = 2.46e-10; mean CPM = 5.558; interferon regulatory factor 8" ID="ID_894269708" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS3: 1.69-fold Up; FDR = 0.000994; PValue = 0.000167; mean CPM = 37.76; suppressor of cytokine signaling 3" ID="ID_568941460" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR1: 1.31-fold Up; FDR = 0.00151; PValue = 0.000268; mean CPM = 37.77; interferon gamma receptor 1" ID="ID_771618899" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HIST1H4F: 1.68-fold Up; FDR = 0.0162; PValue = 0.00411; mean CPM = 53.41; histone cluster 1, H4f" ID="ID_196965245" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR2: 1.23-fold Up; FDR = 0.0258; PValue = 0.00707; mean CPM = 46.52; interferon gamma receptor 2 (interferon gamma transducer 1)" ID="ID_1955493631" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HIST1H4K: 1.36-fold Down; FDR = 0.0491; PValue = 0.015; mean CPM = 23.81; Histone H4" ID="ID_13246389" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_571702073" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF4: 2.95-fold Down; FDR = 0.124; PValue = 0.0456; mean CPM = 0.9773; interferon regulatory factor 4" ID="ID_71683783" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HIST1H4H: 1.22-fold Up; FDR = 0.156; PValue = 0.0604; mean CPM = 205.4; histone cluster 1, H4h" ID="ID_1655397357" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HIST1H4C: 1.33-fold Down; FDR = 0.204; PValue = 0.0842; mean CPM = 188.3; histone cluster 1, H4c" ID="ID_1543913774" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HIST1H4L: 1.43-fold Down; FDR = 0.211; PValue = 0.0877; mean CPM = 23.77; histone cluster 1, H4l" ID="ID_1976992611" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HIST4H4: 1.23-fold Down; FDR = 0.234; PValue = 0.0995; mean CPM = 130.3; histone cluster 4, H4" ID="ID_535213054" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_1209221638" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HIST1H4D: 1.2-fold Down; FDR = 0.655; PValue = 0.371; mean CPM = 77.97; histone cluster 1, H4d" ID="ID_430416286" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_1123886594" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCD: 1.06-fold Up; FDR = 0.696; PValue = 0.404; mean CPM = 37.45; protein kinase C, delta" ID="ID_29989537" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYBB: 1.52-fold Up; FDR = 0.705; PValue = 0.412; mean CPM = 0.9872; cytochrome b-245, beta polypeptide" ID="ID_1469936092" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNB1: 1.79-fold Up; FDR = 0.731; PValue = 0.433; mean CPM = 0.8526; interferon, beta 1, fibroblast" ID="ID_200351035" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HIST1H4B: 1.09-fold Up; FDR = 0.804; PValue = 0.5; mean CPM = 159.3; histone cluster 1, H4b" ID="ID_961620355" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HIST2H4B: 1.09-fold Down; FDR = 0.849; PValue = 0.559; mean CPM = 390.8; histone cluster 2, H4b" ID="ID_1737900112" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_1111866188" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HIST1H4K: 1.07-fold Down; FDR = 0.909; PValue = 0.685; mean CPM = 58.36; histone cluster 1, H4k" ID="ID_819294923" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOS2: 1.4-fold Down; FDR = 0.917; PValue = 0.718; mean CPM = 0.8546; nitric oxide synthase 2, inducible" ID="ID_1640296513" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPI1: 1.12-fold Down; FDR = 0.935; PValue = 0.747; mean CPM = 1.030; spleen focus forming virus (SFFV) proviral integration oncogene spi1" ID="ID_1334651105" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="REG1A: No Change; FDR = 1; PValue = 1; mean CPM = 0.7990; regenerating islet-derived 1 alpha" ID="ID_1095476586" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="REG1A: No Change; FDR = 1; PValue = 1; mean CPM = 0.7825; Uncharacterized protein" ID="ID_600097913" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HIST1H4A: No Change; FDR = 1; PValue = 1; mean CPM = 0.7841; histone cluster 1, H4a" ID="ID_341212759" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Toll-like receptor signaling pathway (WP75:Rev45082): FDR = 6.11e-21, PValue = 6.36e-23" ID="ID_224117867" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TLR2: 8.94-fold Up; FDR = 6.97e-23; PValue = 1.25e-25; mean CPM = 18.41; toll-like receptor 2" ID="ID_1016247813" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL10: 462-fold Up; FDR = 1.01e-21; PValue = 2.65e-24; mean CPM = 286.2; Macaca mulatta chemokine (C-X-C motif) ligand 10 (CXCL10), mRNA." ID="ID_1587815802" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR3: 10.3-fold Up; FDR = 1.95e-21; PValue = 5.6e-24; mean CPM = 35.70; toll-like receptor 3" ID="ID_7040211" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL11: 256-fold Up; FDR = 1e-19; PValue = 3.96e-22; mean CPM = 84.82; chemokine (C-X-C motif) ligand 11" ID="ID_253897828" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL9: 345-fold Up; FDR = 4.16e-19; PValue = 1.97e-21; mean CPM = 175.7; Macaca mulatta chemokine (C-X-C motif) ligand 9 (CXCL9), mRNA." ID="ID_126078553" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_759656334" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF7: 14.8-fold Up; FDR = 7.66e-18; PValue = 4.82e-20; mean CPM = 11.54; Macaca mulatta interferon regulatory factor 7 (IRF7), mRNA." ID="ID_955150834" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_497112362" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LY96: 3.13-fold Up; FDR = 1.27e-10; PValue = 3.43e-12; mean CPM = 6.127; lymphocyte antigen 96" ID="ID_299964617" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR4: 3.45-fold Up; FDR = 3.1e-09; PValue = 1.19e-10; mean CPM = 7.456; Macaca mulatta toll-like receptor 4 (TLR4), mRNA." ID="ID_1996677205" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_1652129380" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK4: 1.8-fold Up; FDR = 3.31e-08; PValue = 1.64e-09; mean CPM = 12.89; interleukin-1 receptor-associated kinase 4" ID="ID_740591192" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1955749868" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL5: 6.74-fold Up; FDR = 2.65e-07; PValue = 1.64e-08; mean CPM = 30.35; chemokine (C-C motif) ligand 5" ID="ID_507830338" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1794103406" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD14: 2.75-fold Down; FDR = 6.54e-07; PValue = 4.46e-08; mean CPM = 5.195; CD14 molecule" ID="ID_933952529" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1761662607" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_185237526" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR2: 1.74-fold Up; FDR = 1.85e-06; PValue = 1.44e-07; mean CPM = 26.05; interferon (alpha, beta and omega) receptor 2" ID="ID_1650118496" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_371718046" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K3: 1.45-fold Down; FDR = 7.01e-06; PValue = 6.34e-07; mean CPM = 180.1; mitogen-activated protein kinase kinase 3" ID="ID_700467483" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_262730883" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPP1: 2.25-fold Down; FDR = 7.74e-05; PValue = 9.29e-06; mean CPM = 35.33; secreted phosphoprotein 1" ID="ID_1643424143" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_161915019" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP2: 1.45-fold Up; FDR = 0.000179; PValue = 2.4e-05; mean CPM = 65.31; TGF-beta activated kinase 1/MAP3K7 binding protein 2" ID="ID_398632598" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40: 2.76-fold Up; FDR = 0.00039; PValue = 5.79e-05; mean CPM = 9.139; CD40 molecule, TNF receptor superfamily member 5" ID="ID_1095752178" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TOLLIP: 1.36-fold Down; FDR = 0.000551; PValue = 8.57e-05; mean CPM = 28.79; Uncharacterized protein" ID="ID_1515515197" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBK1: 1.3-fold Up; FDR = 0.00337; PValue = 0.000674; mean CPM = 30.46; TANK-binding kinase 1" ID="ID_1718341919" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_629170451" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_75747922" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR5: 1.86-fold Down; FDR = 0.00878; PValue = 0.00203; mean CPM = 3.008; toll-like receptor 5" ID="ID_1434906862" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12A: 2.09-fold Up; FDR = 0.00924; PValue = 0.00215; mean CPM = 2.872; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)" ID="ID_1241904880" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR1: 1.27-fold Up; FDR = 0.0101; PValue = 0.00237; mean CPM = 82.39; Uncharacterized protein" ID="ID_102160196" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_62551552" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL8: 2.33-fold Up; FDR = 0.0209; PValue = 0.00552; mean CPM = 2326; interleukin 8" ID="ID_766850468" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_738522323" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_1152433570" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1409472171" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL3: 2.04-fold Down; FDR = 0.067; PValue = 0.0218; mean CPM = 3.575; chemokine (C-C motif) ligand 3" ID="ID_853028118" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K8: 1.35-fold Down; FDR = 0.0831; PValue = 0.0281; mean CPM = 8.912; mitogen-activated protein kinase kinase kinase 8" ID="ID_716419123" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FADD: 1.18-fold Down; FDR = 0.0936; PValue = 0.0324; mean CPM = 30.89; Uncharacterized protein" ID="ID_249096592" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_135763869" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_1721292539" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_330726525" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_1519956326" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_513307711" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP1: 1.12-fold Down; FDR = 0.351; PValue = 0.165; mean CPM = 17.96; TGF-beta activated kinase 1/MAP3K7 binding protein 1" ID="ID_227223297" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1549038415" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TICAM1: 1.11-fold Down; FDR = 0.398; PValue = 0.192; mean CPM = 26.73; toll-like receptor adaptor molecule 1" ID="ID_1646530582" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_714974062" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1153722876" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK12: 1.19-fold Down; FDR = 0.422; PValue = 0.208; mean CPM = 6.569; mitogen-activated protein kinase 12" ID="ID_1453930264" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_635936505" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_177331999" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK13: 1.22-fold Down; FDR = 0.536; PValue = 0.284; mean CPM = 3.100; mitogen-activated protein kinase 13" ID="ID_1573574299" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LBP: 1.52-fold Down; FDR = 0.591; PValue = 0.324; mean CPM = 0.8819; lipopolysaccharide binding protein" ID="ID_1011438018" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF3: 1.07-fold Up; FDR = 0.611; PValue = 0.338; mean CPM = 34.56; TNF receptor-associated factor 3" ID="ID_1110280077" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_616801134" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNB1: 1.79-fold Up; FDR = 0.731; PValue = 0.433; mean CPM = 0.8526; interferon, beta 1, fibroblast" ID="ID_1645042802" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMED7-TICAM2: 1.05-fold Down; FDR = 0.796; PValue = 0.493; mean CPM = 150.6; TMED7-TICAM2 readthrough" ID="ID_131408356" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA6: 1.41-fold Down; FDR = 0.807; PValue = 0.504; mean CPM = 0.8019; interferon, alpha 6" ID="ID_309832369" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR6: 1.07-fold Down; FDR = 0.84; PValue = 0.546; mean CPM = 7.909; toll-like receptor 6" ID="ID_1051434612" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TIRAP: 1.07-fold Up; FDR = 0.841; PValue = 0.548; mean CPM = 8.693; Macaca mulatta toll-interleukin 1 receptor (TIR) domain containing adaptor protein (TIRAP), mRNA." ID="ID_227049805" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF5: 1.06-fold Down; FDR = 0.85; PValue = 0.561; mean CPM = 9.280; interferon regulatory factor 5" ID="ID_1954287433" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_959631568" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_487420737" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR7: 1.37-fold Down; FDR = 0.878; PValue = 0.597; mean CPM = 0.8402; toll-like receptor 7" ID="ID_392566622" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK1: 1.04-fold Down; FDR = 0.885; PValue = 0.606; mean CPM = 41.54; interleukin-1 receptor-associated kinase 1" ID="ID_1568085619" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_236503086" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA13: 1.13-fold Up; FDR = 0.908; PValue = 0.677; mean CPM = 0.7960; interferon, alpha 13" ID="ID_1717430732" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA8: 1.13-fold Down; FDR = 0.911; PValue = 0.702; mean CPM = 0.7910; interferon, alpha 8" ID="ID_1230101136" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKE: 1.03-fold Up; FDR = 0.929; PValue = 0.737; mean CPM = 21.61; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon" ID="ID_1283428322" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA14: 1.22-fold Up; FDR = 0.965; PValue = 0.802; mean CPM = 0.8654; interferon, alpha 14" ID="ID_34179552" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_1344341971" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD80: 1.08-fold Up; FDR = 0.971; PValue = 0.812; mean CPM = 1.157; CD80 molecule" ID="ID_1434739157" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_896865905" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA4: 1.28-fold Down; FDR = 0.983; PValue = 0.829; mean CPM = 0.8584; interferon, alpha 4" ID="ID_1493520831" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12B: 1.07-fold Up; FDR = 0.983; PValue = 0.831; mean CPM = 0.8197; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)" ID="ID_1728028395" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_46503273" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR9: 1.01-fold Down; FDR = 1; PValue = 0.859; mean CPM = 21.45; Macaca mulatta toll-like receptor 9 (TLR9), mRNA." ID="ID_713108847" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR1: 1.02-fold Up; FDR = 1; PValue = 0.945; mean CPM = 1.221; toll-like receptor 1" ID="ID_277701497" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD86: 1.01-fold Down; FDR = 1; PValue = 0.99; mean CPM = 0.8012; CD86 molecule" ID="ID_1738764583" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA1: No Change; FDR = 1; PValue = 0.998; mean CPM = 0.8014; interferon, alpha 1" ID="ID_64030513" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="EPO Receptor Signaling (WP581:Rev41162): FDR = 2.87e-19, PValue = 4.49e-21" ID="ID_798027358" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_805324481" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_707311204" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5A: 2.28-fold Up; FDR = 6.87e-14; PValue = 8.58e-16; mean CPM = 21.55; signal transducer and activator of transcription 5A" ID="ID_1084501821" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_1054447688" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPRU: 2.57-fold Down; FDR = 1.5e-09; PValue = 5.3e-11; mean CPM = 17.80; Uncharacterized protein" ID="ID_13477030" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_869690416" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRS1: 2.78-fold Up; FDR = 7.67e-09; PValue = 3.19e-10; mean CPM = 26.55; Uncharacterized protein" ID="ID_293383789" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_1079016120" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_337244161" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPRC: 6.08-fold Up; FDR = 0.000285; PValue = 4.07e-05; mean CPM = 1.220; protein tyrosine phosphatase, receptor type, C" ID="ID_1278966357" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CISH: 1.95-fold Up; FDR = 0.00116; PValue = 0.0002; mean CPM = 5.083; cytokine inducible SH2-containing protein" ID="ID_1179441455" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EPOR: 1.56-fold Down; FDR = 0.014; PValue = 0.00347; mean CPM = 3.898; erythropoietin receptor" ID="ID_298604124" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1337385737" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_577066501" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1817111654" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_613281077" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_1951728641" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EPO: 1.77-fold Up; FDR = 0.39; PValue = 0.188; mean CPM = 0.9174; Macaca mulatta erythropoietin (EPO), mRNA." ID="ID_491089315" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_843279974" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1624185976" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASA1: 1.03-fold Down; FDR = 0.909; PValue = 0.69; mean CPM = 103.7; Ras GTPase-activating protein 1 isoform 1; Uncharacterized protein" ID="ID_1940095760" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_1109739308" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="NOD pathway (WP1433:Rev45352): FDR = 6.06e-19, PValue = 1.26e-20" ID="ID_1357733404" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="AIM2: 7.87-fold Up; FDR = 4.34e-20; PValue = 1.57e-22; mean CPM = 34.80; absent in melanoma 2" ID="ID_609450501" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP5: 68-fold Up; FDR = 3.54e-19; PValue = 1.64e-21; mean CPM = 7.240; caspase 5, apoptosis-related cysteine peptidase" ID="ID_970384177" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_433969984" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK2: 3.75-fold Up; FDR = 6.1e-16; PValue = 5.38e-18; mean CPM = 68.21; receptor-interacting serine-threonine kinase 2" ID="ID_460001153" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CARD6: 2.33-fold Up; FDR = 1.15e-12; PValue = 1.89e-14; mean CPM = 30.09; caspase recruitment domain family, member 6" ID="ID_266600513" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CARD8: 2.48-fold Up; FDR = 2.44e-11; PValue = 5.59e-13; mean CPM = 14.84; caspase recruitment domain family, member 8" ID="ID_1074091729" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CARD8: 2.02-fold Up; FDR = 1.41e-09; PValue = 4.93e-11; mean CPM = 15.89; caspase recruitment domain family, member 8" ID="ID_1486080753" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1812426002" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRDM1: 3.05-fold Up; FDR = 3.55e-08; PValue = 1.78e-09; mean CPM = 8.715; PR domain containing 1, with ZNF domain" ID="ID_1908679733" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLRC4: 6.6-fold Up; FDR = 8.52e-08; PValue = 4.67e-09; mean CPM = 3.347; NLR family, CARD domain containing 4" ID="ID_789515623" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90AA1: 1.41-fold Up; FDR = 4.17e-05; PValue = 4.62e-06; mean CPM = 609.6; heat shock protein 90kDa alpha (cytosolic), class A member 2" ID="ID_1143051976" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CARD9: 1.53-fold Up; FDR = 9.57e-05; PValue = 1.18e-05; mean CPM = 16.72; caspase recruitment domain family, member 9" ID="ID_302837174" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOD1: 1.63-fold Up; FDR = 0.000193; PValue = 2.61e-05; mean CPM = 58.36; nucleotide-binding oligomerization domain containing 1" ID="ID_1869610350" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SUGT1: 1.35-fold Up; FDR = 0.000193; PValue = 2.61e-05; mean CPM = 54.75; SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)" ID="ID_873203213" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1314279144" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL18: 1.5-fold Down; FDR = 0.00981; PValue = 0.0023; mean CPM = 6.489; interleukin 18 (interferon-gamma-inducing factor)" ID="ID_1049470784" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_856320037" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XIAP: 1.17-fold Up; FDR = 0.177; PValue = 0.0706; mean CPM = 19.21; X-linked inhibitor of apoptosis" ID="ID_284634331" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACAP1: 1.42-fold Down; FDR = 0.179; PValue = 0.0717; mean CPM = 2.333; ArfGAP with coiled-coil, ankyrin repeat and PH domains 1" ID="ID_804997769" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP7: 1.15-fold Up; FDR = 0.218; PValue = 0.0916; mean CPM = 21.49; caspase 7, apoptosis-related cysteine peptidase" ID="ID_1745952001" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PYCARD: 1.38-fold Down; FDR = 0.241; PValue = 0.103; mean CPM = 3.110; PYD and CARD domain containing" ID="ID_870241057" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLRP3: 1.84-fold Down; FDR = 0.32; PValue = 0.147; mean CPM = 0.9630; NLR family, pyrin domain containing 3" ID="ID_539397351" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COPS6: 1.06-fold Down; FDR = 0.655; PValue = 0.371; mean CPM = 93.74; COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)" ID="ID_312705967" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_91780808" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90AA1: 1.8-fold Up; FDR = 0.749; PValue = 0.449; mean CPM = 0.8328; heat shock protein 90kDa alpha (cytosolic), class A member 1" ID="ID_1416480813" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MEFV: 1.13-fold Up; FDR = 0.813; PValue = 0.51; mean CPM = 6.740; Mediterranean fever" ID="ID_437767998" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_960017124" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOD2: 1.17-fold Up; FDR = 0.866; PValue = 0.583; mean CPM = 1.911; nucleotide-binding oligomerization domain containing 2" ID="ID_1081647409" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLRP10: 1.48-fold Up; FDR = 0.868; PValue = 0.586; mean CPM = 0.8220; NLR family, pyrin domain containing 10" ID="ID_1928393914" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DUOX2: 1.22-fold Down; FDR = 0.898; PValue = 0.625; mean CPM = 1.000; dual oxidase 2" ID="ID_771025141" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLRP7: 1.15-fold Down; FDR = 0.906; PValue = 0.672; mean CPM = 0.7909; NLR family, pyrin domain containing 7" ID="ID_1364927734" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_1486553845" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP9: 1.01-fold Up; FDR = 1; PValue = 0.908; mean CPM = 19.86; caspase 9, apoptosis-related cysteine peptidase" ID="ID_636762206" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLRP4: 1.05-fold Down; FDR = 1; PValue = 0.911; mean CPM = 0.8249; NLR family, pyrin domain containing 4" ID="ID_818992202" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Complement Activation, Classical Pathway (WP545:Rev41148): FDR = 2.66e-18, PValue = 6.93e-20" ID="ID_1058422060" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="C4B: 24.3-fold Up; FDR = 1.01e-20; PValue = 3.32e-23; mean CPM = 65.82; Complement C4-B Precursor (Basic complement C4)(C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3) [Contains Complement C4 beta chain;Complement C4-B alpha chain;C4a anaphylatoxin;C4b-B;C4d-B;Complement C4 gamma chain]" ID="ID_1265027708" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C2: 4.8-fold Up; FDR = 3.21e-17; PValue = 2.26e-19; mean CPM = 200.3; Uncharacterized protein" ID="ID_1664821864" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C3: 5.35-fold Up; FDR = 5.79e-07; PValue = 3.91e-08; mean CPM = 19.68; complement component 3" ID="ID_1481209408" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C5: 2.29-fold Up; FDR = 0.0212; PValue = 0.00561; mean CPM = 1.418; complement component 5" ID="ID_1577938198" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C1QB: 2.62-fold Up; FDR = 0.0887; PValue = 0.0304; mean CPM = 1.092; complement component 1, q subcomponent, B chain" ID="ID_1283501766" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C1QC: 2.02-fold Up; FDR = 0.203; PValue = 0.0839; mean CPM = 1.322; complement component 1, q subcomponent, C chain" ID="ID_1079087238" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MASP1: 1.46-fold Down; FDR = 0.264; PValue = 0.115; mean CPM = 4.467; mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)" ID="ID_377174249" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C8B: 2.74-fold Up; FDR = 0.396; PValue = 0.192; mean CPM = 0.8553; complement component 8, beta polypeptide" ID="ID_1658267065" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C9: 1.41-fold Up; FDR = 0.505; PValue = 0.262; mean CPM = 1.295; complement component 9" ID="ID_86494544" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C6: 1.72-fold Down; FDR = 0.856; PValue = 0.57; mean CPM = 0.8334; complement component 6" ID="ID_650421856" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C8A: 1.06-fold Up; FDR = 0.968; PValue = 0.808; mean CPM = 0.8260; complement component 8, alpha polypeptide" ID="ID_1836810748" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C7: 1.11-fold Up; FDR = 1; PValue = 0.883; mean CPM = 0.8197; complement component 7" ID="ID_1770251328" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Regulation of toll-like receptor signaling pathway (WP1449:Rev45049): FDR = 5.99e-18, PValue = 1.87e-19" ID="ID_118070044" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TLR2: 8.94-fold Up; FDR = 6.97e-23; PValue = 1.25e-25; mean CPM = 18.41; toll-like receptor 2" ID="ID_1703084489" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL10: 462-fold Up; FDR = 1.01e-21; PValue = 2.65e-24; mean CPM = 286.2; Macaca mulatta chemokine (C-X-C motif) ligand 10 (CXCL10), mRNA." ID="ID_1637126660" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR3: 10.3-fold Up; FDR = 1.95e-21; PValue = 5.6e-24; mean CPM = 35.70; toll-like receptor 3" ID="ID_767316039" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL11: 256-fold Up; FDR = 1e-19; PValue = 3.96e-22; mean CPM = 84.82; chemokine (C-X-C motif) ligand 11" ID="ID_1761464286" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RBCK1: 2.19-fold Up; FDR = 2.7e-19; PValue = 1.18e-21; mean CPM = 118.3; RanBP-type and C3HC4-type zinc finger containing 1" ID="ID_1509196924" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL9: 345-fold Up; FDR = 4.16e-19; PValue = 1.97e-21; mean CPM = 175.7; Macaca mulatta chemokine (C-X-C motif) ligand 9 (CXCL9), mRNA." ID="ID_176869564" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_95900743" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF7: 14.8-fold Up; FDR = 7.66e-18; PValue = 4.82e-20; mean CPM = 11.54; Macaca mulatta interferon regulatory factor 7 (IRF7), mRNA." ID="ID_1134385713" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_109517827" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAFD1: 2.07-fold Up; FDR = 4.13e-13; PValue = 6.18e-15; mean CPM = 152.6; TRAF-type zinc finger domain containing 1" ID="ID_1078745625" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LY96: 3.13-fold Up; FDR = 1.27e-10; PValue = 3.43e-12; mean CPM = 6.127; lymphocyte antigen 96" ID="ID_1674083576" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR4: 3.45-fold Up; FDR = 3.1e-09; PValue = 1.19e-10; mean CPM = 7.456; Macaca mulatta toll-like receptor 4 (TLR4), mRNA." ID="ID_1328465662" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PELI1: 2-fold Up; FDR = 5.5e-09; PValue = 2.23e-10; mean CPM = 30.48; pellino homolog 1 (Drosophila)" ID="ID_109991409" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NEU1: 1.73-fold Down; FDR = 5.89e-09; PValue = 2.4e-10; mean CPM = 44.30; Sialidase-1 Precursor (EC 3.2.1.18)(Lysosomal sialidase)(N-acetyl-alpha-neuraminidase 1)(Acetylneuraminyl hydrolase)(G9 sialidase)" ID="ID_1797112860" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_980864026" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK4: 1.8-fold Up; FDR = 3.31e-08; PValue = 1.64e-09; mean CPM = 12.89; interleukin-1 receptor-associated kinase 4" ID="ID_283340910" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1750740981" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL5: 6.74-fold Up; FDR = 2.65e-07; PValue = 1.64e-08; mean CPM = 30.35; chemokine (C-C motif) ligand 5" ID="ID_1327132596" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_358018469" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD14: 2.75-fold Down; FDR = 6.54e-07; PValue = 4.46e-08; mean CPM = 5.195; CD14 molecule" ID="ID_1480405221" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYLD: 1.46-fold Up; FDR = 1.36e-06; PValue = 1.01e-07; mean CPM = 77.47; cylindromatosis (turban tumor syndrome)" ID="ID_547856284" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_908102474" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_773865454" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR2: 1.74-fold Up; FDR = 1.85e-06; PValue = 1.44e-07; mean CPM = 26.05; interferon (alpha, beta and omega) receptor 2" ID="ID_1350929595" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_167981046" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TREM1: 5.53-fold Down; FDR = 4.59e-06; PValue = 3.91e-07; mean CPM = 22.68; triggering receptor expressed on myeloid cells 1" ID="ID_698240938" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K3: 1.45-fold Down; FDR = 7.01e-06; PValue = 6.34e-07; mean CPM = 180.1; mitogen-activated protein kinase kinase 3" ID="ID_1196298480" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_57681985" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFAIP3: 1.79-fold Up; FDR = 3.14e-05; PValue = 3.34e-06; mean CPM = 52.47; tumor necrosis factor, alpha-induced protein 3" ID="ID_148546354" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLK1: 2.25-fold Down; FDR = 3.23e-05; PValue = 3.46e-06; mean CPM = 27.29; polo-like kinase 1 (Drosophila)" ID="ID_844487452" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPP1: 2.25-fold Down; FDR = 7.74e-05; PValue = 9.29e-06; mean CPM = 35.33; secreted phosphoprotein 1" ID="ID_918878787" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_1705813290" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTNNAL1: 1.4-fold Down; FDR = 0.000133; PValue = 1.7e-05; mean CPM = 134.1; catenin (cadherin-associated protein), alpha-like 1" ID="ID_199923587" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP2: 1.45-fold Up; FDR = 0.000179; PValue = 2.4e-05; mean CPM = 65.31; TGF-beta activated kinase 1/MAP3K7 binding protein 2" ID="ID_480660882" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP3: 1.5-fold Up; FDR = 0.000276; PValue = 3.92e-05; mean CPM = 11.67; TGF-beta activated kinase 1/MAP3K7 binding protein 3" ID="ID_1949982293" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40: 2.76-fold Up; FDR = 0.00039; PValue = 5.79e-05; mean CPM = 9.139; CD40 molecule, TNF receptor superfamily member 5" ID="ID_1598991174" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TOLLIP: 1.36-fold Down; FDR = 0.000551; PValue = 8.57e-05; mean CPM = 28.79; Uncharacterized protein" ID="ID_24228588" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CISH: 1.95-fold Up; FDR = 0.00116; PValue = 0.0002; mean CPM = 5.083; cytokine inducible SH2-containing protein" ID="ID_8738369" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBK1: 1.3-fold Up; FDR = 0.00337; PValue = 0.000674; mean CPM = 30.46; TANK-binding kinase 1" ID="ID_376819669" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RNF216: 1.26-fold Down; FDR = 0.00452; PValue = 0.000946; mean CPM = 59.60; ring finger protein 216" ID="ID_1495294542" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_24198782" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_1764518093" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK3: 1.54-fold Up; FDR = 0.00653; PValue = 0.00144; mean CPM = 19.97; interleukin-1 receptor-associated kinase 3" ID="ID_1578985011" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR5: 1.86-fold Down; FDR = 0.00878; PValue = 0.00203; mean CPM = 3.008; toll-like receptor 5" ID="ID_104359626" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12A: 2.09-fold Up; FDR = 0.00924; PValue = 0.00215; mean CPM = 2.872; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)" ID="ID_1915881346" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR1: 1.27-fold Up; FDR = 0.0101; PValue = 0.00237; mean CPM = 82.39; Uncharacterized protein" ID="ID_691454026" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SARM1: 1.69-fold Up; FDR = 0.0194; PValue = 0.00509; mean CPM = 5.456; sterile alpha and TIR motif containing 1" ID="ID_290385193" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PELI2: 1.41-fold Down; FDR = 0.0196; PValue = 0.00515; mean CPM = 6.598; pellino homolog 2 (Drosophila)" ID="ID_1112314797" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_609206935" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL8: 2.33-fold Up; FDR = 0.0209; PValue = 0.00552; mean CPM = 2326; interleukin 8" ID="ID_723193351" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_889445199" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_1485457346" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1411252053" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RNF31: 1.19-fold Up; FDR = 0.0502; PValue = 0.0154; mean CPM = 52.31; ring finger protein 31" ID="ID_1864399916" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL3: 2.04-fold Down; FDR = 0.067; PValue = 0.0218; mean CPM = 3.575; chemokine (C-C motif) ligand 3" ID="ID_1203467737" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K8: 1.35-fold Down; FDR = 0.0831; PValue = 0.0281; mean CPM = 8.912; mitogen-activated protein kinase kinase kinase 8" ID="ID_17241683" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="OTUD5: 1.16-fold Down; FDR = 0.0921; PValue = 0.0318; mean CPM = 54.00; OTU domain containing 5" ID="ID_1500832899" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FADD: 1.18-fold Down; FDR = 0.0936; PValue = 0.0324; mean CPM = 30.89; Uncharacterized protein" ID="ID_1844459153" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RNF41: 1.17-fold Down; FDR = 0.0994; PValue = 0.0348; mean CPM = 33.28; ring finger protein 41" ID="ID_1208689294" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_1671436455" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_857662136" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_656609407" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CUEDC2: 1.13-fold Up; FDR = 0.188; PValue = 0.0762; mean CPM = 58.93; CUE domain containing 2" ID="ID_313438852" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK2: 1.27-fold Down; FDR = 0.259; PValue = 0.113; mean CPM = 10.13; interleukin-1 receptor-associated kinase 2" ID="ID_1088394167" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FBXW5: 1.12-fold Down; FDR = 0.263; PValue = 0.115; mean CPM = 70.62; Uncharacterized protein" ID="ID_347298555" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_119133025" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SQSTM1: 1.19-fold Down; FDR = 0.289; PValue = 0.129; mean CPM = 270.1; sequestosome 1" ID="ID_1022428587" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_1574767443" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP1: 1.12-fold Down; FDR = 0.351; PValue = 0.165; mean CPM = 17.96; TGF-beta activated kinase 1/MAP3K7 binding protein 1" ID="ID_1166495810" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PELI3: 1.17-fold Down; FDR = 0.381; PValue = 0.182; mean CPM = 8.442; pellino homolog 3 (Drosophila)" ID="ID_1108580826" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1829774690" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TICAM1: 1.11-fold Down; FDR = 0.398; PValue = 0.192; mean CPM = 26.73; toll-like receptor adaptor molecule 1" ID="ID_1323414298" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_821805172" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_67059526" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK12: 1.19-fold Down; FDR = 0.422; PValue = 0.208; mean CPM = 6.569; mitogen-activated protein kinase 12" ID="ID_1860819327" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SIGIRR: 1.29-fold Up; FDR = 0.437; PValue = 0.217; mean CPM = 2.330; single immunoglobulin and toll-interleukin 1 receptor (TIR) domain" ID="ID_753961358" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_987055287" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_1881061214" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK13: 1.22-fold Down; FDR = 0.536; PValue = 0.284; mean CPM = 3.100; mitogen-activated protein kinase 13" ID="ID_1099363585" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LBP: 1.52-fold Down; FDR = 0.591; PValue = 0.324; mean CPM = 0.8819; lipopolysaccharide binding protein" ID="ID_581177266" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF3: 1.07-fold Up; FDR = 0.611; PValue = 0.338; mean CPM = 34.56; TNF receptor-associated factor 3" ID="ID_38595745" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZMYND11: 1.06-fold Up; FDR = 0.655; PValue = 0.371; mean CPM = 72.68; zinc finger, MYND domain containing 11" ID="ID_1178864805" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_955774021" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNB1: 1.79-fold Up; FDR = 0.731; PValue = 0.433; mean CPM = 0.8526; interferon, beta 1, fibroblast" ID="ID_42065534" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMED7-TICAM2: 1.05-fold Down; FDR = 0.796; PValue = 0.493; mean CPM = 150.6; TMED7-TICAM2 readthrough" ID="ID_1608521335" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA6: 1.41-fold Down; FDR = 0.807; PValue = 0.504; mean CPM = 0.8019; interferon, alpha 6" ID="ID_1876923112" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR6: 1.07-fold Down; FDR = 0.84; PValue = 0.546; mean CPM = 7.909; toll-like receptor 6" ID="ID_1755244208" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TIRAP: 1.07-fold Up; FDR = 0.841; PValue = 0.548; mean CPM = 8.693; Macaca mulatta toll-interleukin 1 receptor (TIR) domain containing adaptor protein (TIRAP), mRNA." ID="ID_326341907" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SFTPA1: 1.39-fold Down; FDR = 0.845; PValue = 0.554; mean CPM = 0.8018; Pulmonary surfactant-associated protein A" ID="ID_166049396" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SFTPA1: 1.39-fold Down; FDR = 0.845; PValue = 0.554; mean CPM = 0.8018; Pulmonary surfactant-associated protein A" ID="ID_1367947099" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF5: 1.06-fold Down; FDR = 0.85; PValue = 0.561; mean CPM = 9.280; interferon regulatory factor 5" ID="ID_1985241279" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MBL2: 1.3-fold Up; FDR = 0.85; PValue = 0.561; mean CPM = 0.7954; mannose-binding lectin (protein C) 2, soluble (opsonic defect)" ID="ID_2272353" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1593214589" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD180: 1.69-fold Down; FDR = 0.868; PValue = 0.585; mean CPM = 0.8488; CD180 molecule" ID="ID_1455167853" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1131770134" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR7: 1.37-fold Down; FDR = 0.878; PValue = 0.597; mean CPM = 0.8402; toll-like receptor 7" ID="ID_793060572" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK1: 1.04-fold Down; FDR = 0.885; PValue = 0.606; mean CPM = 41.54; interleukin-1 receptor-associated kinase 1" ID="ID_637237489" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_367825624" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SFTPA1: 1.19-fold Up; FDR = 0.903; PValue = 0.645; mean CPM = 0.7982; surfactant protein A1" ID="ID_1356184725" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA13: 1.13-fold Up; FDR = 0.908; PValue = 0.677; mean CPM = 0.7960; interferon, alpha 13" ID="ID_1152704640" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA8: 1.13-fold Down; FDR = 0.911; PValue = 0.702; mean CPM = 0.7910; interferon, alpha 8" ID="ID_1356584795" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKE: 1.03-fold Up; FDR = 0.929; PValue = 0.737; mean CPM = 21.61; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon" ID="ID_99046739" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA14: 1.22-fold Up; FDR = 0.965; PValue = 0.802; mean CPM = 0.8654; interferon, alpha 14" ID="ID_1930184608" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_1933092709" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD80: 1.08-fold Up; FDR = 0.971; PValue = 0.812; mean CPM = 1.157; CD80 molecule" ID="ID_1543156391" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_934690208" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA4: 1.28-fold Down; FDR = 0.983; PValue = 0.829; mean CPM = 0.8584; interferon, alpha 4" ID="ID_1886337298" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12B: 1.07-fold Up; FDR = 0.983; PValue = 0.831; mean CPM = 0.8197; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)" ID="ID_1781840668" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_480298016" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR9: 1.01-fold Down; FDR = 1; PValue = 0.859; mean CPM = 21.45; Macaca mulatta toll-like receptor 9 (TLR9), mRNA." ID="ID_1786018450" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR1: 1.02-fold Up; FDR = 1; PValue = 0.945; mean CPM = 1.221; toll-like receptor 1" ID="ID_941145916" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BTK: No Change; FDR = 1; PValue = 0.965; mean CPM = 0.8336; Bruton agammaglobulinemia tyrosine kinase" ID="ID_38520680" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SYK: 1.11-fold Up; FDR = 1; PValue = 0.977; mean CPM = 0.8420; spleen tyrosine kinase" ID="ID_893418893" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SFTPD: 1.03-fold Down; FDR = 1; PValue = 0.982; mean CPM = 0.8042; surfactant protein D" ID="ID_1700925064" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD86: 1.01-fold Down; FDR = 1; PValue = 0.99; mean CPM = 0.8012; CD86 molecule" ID="ID_519549746" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA1: No Change; FDR = 1; PValue = 0.998; mean CPM = 0.8014; interferon, alpha 1" ID="ID_547193891" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Fatty Acid Biosynthesis (WP357:Rev45261): FDR = 1.39e-17, PValue = 5.08e-19" ID="ID_566868467" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="ACSL1: 6.98-fold Up; FDR = 1.75e-21; PValue = 4.92e-24; mean CPM = 194.6; acyl-CoA synthetase long-chain family member 1" ID="ID_1564733806" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACSL5: 8.65-fold Up; FDR = 4.07e-18; PValue = 2.39e-20; mean CPM = 34.19; acyl-CoA synthetase long-chain family member 5" ID="ID_1528319323" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PC: 2.94-fold Down; FDR = 2.05e-12; PValue = 3.55e-14; mean CPM = 48.99; pyruvate carboxylase" ID="ID_1430579912" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DECR1: 1.83-fold Up; FDR = 2.91e-10; PValue = 8.64e-12; mean CPM = 54.00; 2,4-dienoyl-CoA reductase, mitochondrial; Uncharacterized protein" ID="ID_1258197300" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FASN: 2.14-fold Down; FDR = 1.36e-09; PValue = 4.74e-11; mean CPM = 192.4; fatty acid synthase" ID="ID_1752760121" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ECHDC1: 1.64-fold Up; FDR = 3.51e-07; PValue = 2.24e-08; mean CPM = 36.83; enoyl CoA hydratase domain containing 1" ID="ID_1348841431" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACSL4: 1.44-fold Up; FDR = 2.98e-05; PValue = 3.15e-06; mean CPM = 126.3; acyl-CoA synthetase long-chain family member 4" ID="ID_1214703742" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACACA: 1.27-fold Down; FDR = 0.00395; PValue = 0.000809; mean CPM = 54.13; acetyl-CoA carboxylase alpha" ID="ID_1351540538" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PECR: 1.44-fold Up; FDR = 0.00406; PValue = 0.000836; mean CPM = 12.33; peroxisomal trans-2-enoyl-CoA reductase" ID="ID_166895915" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SCD: 1.92-fold Down; FDR = 0.0103; PValue = 0.00244; mean CPM = 11.46; stearoyl-CoA desaturase (delta-9-desaturase)" ID="ID_1094187809" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACSL6: 2.32-fold Down; FDR = 0.0551; PValue = 0.0173; mean CPM = 1.472; acyl-CoA synthetase long-chain family member 6" ID="ID_1558881141" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000024909: 1.17-fold Down; FDR = 0.0796; PValue = 0.0267; mean CPM = 110.7; Uncharacterized protein" ID="ID_1499334589" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ECH1: 1.14-fold Up; FDR = 0.182; PValue = 0.0729; mean CPM = 60.46; enoyl CoA hydratase 1, peroxisomal" ID="ID_1817513824" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACAA2: 1.13-fold Up; FDR = 0.198; PValue = 0.0811; mean CPM = 42.36; acetyl-CoA acyltransferase 2" ID="ID_1930002786" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MECR: 1.13-fold Down; FDR = 0.363; PValue = 0.172; mean CPM = 13.95; mitochondrial trans-2-enoyl-CoA reductase" ID="ID_1067315331" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HADH: 1.1-fold Up; FDR = 0.419; PValue = 0.205; mean CPM = 32.14; hydroxyacyl-CoA dehydrogenase" ID="ID_844362243" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACSS2: 1.05-fold Down; FDR = 0.773; PValue = 0.471; mean CPM = 38.17; Uncharacterized protein" ID="ID_1539472660" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACSL3: 1.05-fold Up; FDR = 0.787; PValue = 0.484; mean CPM = 61.21; acyl-CoA synthetase long-chain family member 3" ID="ID_436364816" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ECHDC3: 1.07-fold Up; FDR = 0.813; PValue = 0.51; mean CPM = 10.66; Uncharacterized protein" ID="ID_43248762" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACLY: 1.02-fold Down; FDR = 0.928; PValue = 0.737; mean CPM = 42.39; ATP citrate lyase; Uncharacterized protein" ID="ID_1683638574" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ECHS1: 1.01-fold Up; FDR = 1; PValue = 0.885; mean CPM = 49.79; enoyl CoA hydratase, short chain, 1, mitochondrial" ID="ID_1594066812" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-7 signaling pathway (WP205:Rev45369): FDR = 2.34e-17, PValue = 9.77e-19" ID="ID_1023732821" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_593316822" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5A: 2.28-fold Up; FDR = 6.87e-14; PValue = 8.58e-16; mean CPM = 21.55; signal transducer and activator of transcription 5A" ID="ID_604811819" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL7: 9.03-fold Up; FDR = 1.39e-13; PValue = 1.9e-15; mean CPM = 5.288; interleukin 7" ID="ID_1770959496" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_227395376" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1B: 1.64-fold Up; FDR = 1.22e-08; PValue = 5.39e-10; mean CPM = 32.96; Cyclin-dependent kinase inhibitor 1B; Uncharacterized protein" ID="ID_1857245434" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2B: 3.54-fold Up; FDR = 1.24e-07; PValue = 7.07e-09; mean CPM = 5.971; PTK2B protein tyrosine kinase 2 beta" ID="ID_1924224874" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_356775542" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L1: 1.51-fold Up; FDR = 9.13e-07; PValue = 6.52e-08; mean CPM = 66.15; Bcl-2-like protein 1; Bcl-2-like protein 1 isoform 1; Uncharacterized protein" ID="ID_1119287908" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_290540729" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_501502732" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAD: 1.36-fold Down; FDR = 0.000605; PValue = 9.52e-05; mean CPM = 48.46; BCL2-associated agonist of cell death" ID="ID_1263525980" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK3: 2.31-fold Up; FDR = 0.00186; PValue = 0.000342; mean CPM = 2.154; Janus kinase 3" ID="ID_1551673714" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FYN: 1.22-fold Up; FDR = 0.0156; PValue = 0.00393; mean CPM = 92.94; FYN oncogene related to SRC, FGR, YES" ID="ID_1799360334" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_933043313" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1515211415" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_1643064267" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL7R: 1.76-fold Down; FDR = 0.0698; PValue = 0.0229; mean CPM = 3.067; interleukin 7 receptor" ID="ID_1609810915" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_189070247" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND1: 1.17-fold Up; FDR = 0.121; PValue = 0.0443; mean CPM = 867.3; cyclin D1" ID="ID_815252991" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_781824364" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1699214588" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1687043240" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2RA: 1.08-fold Up; FDR = 0.945; PValue = 0.766; mean CPM = 0.8493; interleukin 2 receptor, alpha" ID="ID_1510735306" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-6 signaling pathway (WP364:Rev44848): FDR = 2.56e-17, PValue = 1.2e-18" ID="ID_1326897487" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="IRF1: 18.6-fold Up; FDR = 1.53e-21; PValue = 4.24e-24; mean CPM = 240.7; interferon regulatory factor 1" ID="ID_1943974724" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_1892787229" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_898189749" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_475766457" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_1668291093" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL6ST: 1.78-fold Up; FDR = 1.86e-08; PValue = 8.65e-10; mean CPM = 437.6; interleukin 6 signal transducer (gp130, oncostatin M receptor)" ID="ID_1640933045" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRDM1: 3.05-fold Up; FDR = 3.55e-08; PValue = 1.78e-09; mean CPM = 8.715; PR domain containing 1, with ZNF domain" ID="ID_91036501" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_142053665" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L1: 1.51-fold Up; FDR = 9.13e-07; PValue = 6.52e-08; mean CPM = 66.15; Bcl-2-like protein 1; Bcl-2-like protein 1 isoform 1; Uncharacterized protein" ID="ID_1117149719" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1785822248" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL6R: 3.84-fold Down; FDR = 6.68e-05; PValue = 7.89e-06; mean CPM = 4.840; interleukin 6 receptor" ID="ID_1332784779" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAD: 1.36-fold Down; FDR = 0.000605; PValue = 9.52e-05; mean CPM = 48.46; BCL2-associated agonist of cell death" ID="ID_1850761400" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS3: 1.69-fold Up; FDR = 0.000994; PValue = 0.000167; mean CPM = 37.76; suppressor of cytokine signaling 3" ID="ID_86281216" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYK2: 1.24-fold Down; FDR = 0.0142; PValue = 0.00354; mean CPM = 42.58; tyrosine kinase 2" ID="ID_33368009" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC1: 1.25-fold Up; FDR = 0.0159; PValue = 0.00403; mean CPM = 27.51; histone deacetylase 1" ID="ID_859901717" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1140156825" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_930655609" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_58667201" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCOA1: 1.18-fold Up; FDR = 0.112; PValue = 0.04; mean CPM = 20.42; nuclear receptor coactivator 1" ID="ID_1740678466" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_1678280591" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="A2M: 1.33-fold Up; FDR = 0.181; PValue = 0.0726; mean CPM = 750.0; alpha-2-macroglobulin" ID="ID_1486703137" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1439982573" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_1278188478" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_553917565" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_1318417066" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCD: 1.06-fold Up; FDR = 0.696; PValue = 0.404; mean CPM = 37.45; protein kinase C, delta" ID="ID_666603659" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HCK: 1.3-fold Down; FDR = 0.797; PValue = 0.494; mean CPM = 0.9272; Uncharacterized protein" ID="ID_1769657198" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV1: 1.25-fold Down; FDR = 0.858; PValue = 0.572; mean CPM = 0.9515; vav 1 guanine nucleotide exchange factor" ID="ID_401982497" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_765007689" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB1: 1.04-fold Up; FDR = 0.88; PValue = 0.6; mean CPM = 30.80; Uncharacterized protein" ID="ID_474751760" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_90982970" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREBBP: 1.01-fold Down; FDR = 0.993; PValue = 0.847; mean CPM = 137.7; CREB binding protein" ID="ID_1310155084" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_1393872147" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLK: No Change; FDR = 1; PValue = 0.97; mean CPM = 11.78; nemo-like kinase" ID="ID_1125280721" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AGT: 1.02-fold Down; FDR = 1; PValue = 0.996; mean CPM = 0.8004; angiotensinogen (serpin peptidase inhibitor, clade A, member 8)" ID="ID_534634540" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRP: No Change; FDR = 1; PValue = 1; mean CPM = 0.7818; Uncharacterized protein" ID="ID_1897348955" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-9 signaling pathway (WP22:Rev45370): FDR = 3.37e-17, PValue = 1.75e-18" ID="ID_1139783203" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_264103207" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_743919010" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1179164700" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_1972951769" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1276427964" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK3: 2.31-fold Up; FDR = 0.00186; PValue = 0.000342; mean CPM = 2.154; Janus kinase 3" ID="ID_1452116270" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1780689981" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_1294790044" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_686605511" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_39422158" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL9R: 2.21-fold Down; FDR = 0.63; PValue = 0.352; mean CPM = 0.8661; interleukin 9 receptor" ID="ID_1205063483" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1269565438" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL9: 1.14-fold Up; FDR = 0.911; PValue = 0.705; mean CPM = 0.7910; interleukin 9" ID="ID_96716053" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK9: 1.02-fold Down; FDR = 0.942; PValue = 0.76; mean CPM = 37.82; cyclin-dependent kinase 9" ID="ID_1194555873" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Proteasome Degradation (WP183:Rev45274): FDR = 5.63e-17, PValue = 3.22e-18" ID="ID_1682868725" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="PSMB8: 15.4-fold Up; FDR = 1.64e-26; PValue = 5.69e-30; mean CPM = 246.0; proteasome subunit beta type-8 isoform E1 proprotein" ID="ID_288645381" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMB10: 13.4-fold Up; FDR = 5.15e-26; PValue = 2.42e-29; mean CPM = 202.9; Proteasome subunit beta type" ID="ID_475804963" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMB9: 18.6-fold Up; FDR = 5.15e-24; PValue = 5.86e-27; mean CPM = 380.3; proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)" ID="ID_675046252" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSME1: 5.25-fold Up; FDR = 7.8e-24; PValue = 9.53e-27; mean CPM = 157.6; Uncharacterized protein" ID="ID_1099137136" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000027180: 6.97-fold Up; FDR = 1.24e-21; PValue = 3.39e-24; mean CPM = 285.4; Uncharacterized protein" ID="ID_1522160402" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000027180: 6.97-fold Up; FDR = 1.24e-21; PValue = 3.39e-24; mean CPM = 285.4; Uncharacterized protein" ID="ID_1497952598" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000005183: 4.07-fold Up; FDR = 2.87e-21; PValue = 8.51e-24; mean CPM = 164.7; Uncharacterized protein" ID="ID_787602360" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000005183: 4.07-fold Up; FDR = 2.87e-21; PValue = 8.51e-24; mean CPM = 164.7; Uncharacterized protein" ID="ID_1258272119" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-B: 6.07-fold Up; FDR = 2.71e-19; PValue = 1.2e-21; mean CPM = 2098; Uncharacterized protein" ID="ID_520508479" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMA6: 3.39-fold Up; FDR = 3.27e-19; PValue = 1.49e-21; mean CPM = 174.6; proteasome (prosome, macropain) subunit, alpha type, 6" ID="ID_75093836" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMA4: 2.69-fold Up; FDR = 1.03e-16; PValue = 8.26e-19; mean CPM = 125.7; proteasome (prosome, macropain) subunit, alpha type, 4" ID="ID_595544984" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="UBA7: 2.28-fold Up; FDR = 4.07e-15; PValue = 4.01e-17; mean CPM = 75.25; ubiquitin-like modifier activating enzyme 7" ID="ID_1535259957" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMA2: 1.94-fold Up; FDR = 8.77e-14; PValue = 1.15e-15; mean CPM = 126.0; proteasome (prosome, macropain) subunit, alpha type, 2" ID="ID_1394004439" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMA3: 1.97-fold Up; FDR = 2.59e-12; PValue = 4.66e-14; mean CPM = 94.63; proteasome (prosome, macropain) subunit, alpha type, 3" ID="ID_1643729410" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMA5: 1.71-fold Up; FDR = 2.64e-10; PValue = 7.81e-12; mean CPM = 103.0; proteasome (prosome, macropain) subunit, alpha type, 5" ID="ID_1047393220" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMA1: 1.56-fold Up; FDR = 9.63e-09; PValue = 4.15e-10; mean CPM = 100.6; proteasome (prosome, macropain) subunit, alpha type, 1" ID="ID_20073629" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMB1: 1.54-fold Up; FDR = 3.38e-08; PValue = 1.68e-09; mean CPM = 193.0; proteasome (prosome, macropain) subunit, beta type, 1" ID="ID_1213547890" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMD10: 1.44-fold Up; FDR = 0.000408; PValue = 6.1e-05; mean CPM = 18.47; proteasome (prosome, macropain) 26S subunit, non-ATPase, 10" ID="ID_1838617654" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMB7: 1.32-fold Up; FDR = 0.000758; PValue = 0.000123; mean CPM = 186.3; proteasome (prosome, macropain) subunit, beta type, 7" ID="ID_135622494" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMA7: 1.3-fold Up; FDR = 0.00111; PValue = 0.00019; mean CPM = 83.97; proteasome (prosome, macropain) subunit, alpha type, 7" ID="ID_181503738" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="H2AFX: 1.51-fold Down; FDR = 0.00139; PValue = 0.000246; mean CPM = 50.91; H2A histone family, member X" ID="ID_1442999769" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="UBE2D1: 1.53-fold Up; FDR = 0.00256; PValue = 0.000491; mean CPM = 9.796; ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)" ID="ID_739377895" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="UBA1: 1.29-fold Down; FDR = 0.00274; PValue = 0.000529; mean CPM = 454.0; ubiquitin-like modifier activating enzyme 1" ID="ID_525900678" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="UBE2D3: 1.26-fold Up; FDR = 0.00529; PValue = 0.00113; mean CPM = 129.0; Uncharacterized protein" ID="ID_1959752480" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMB2: 1.26-fold Up; FDR = 0.00539; PValue = 0.00116; mean CPM = 75.44; Proteasome subunit beta type" ID="ID_1014824424" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMB4: 1.25-fold Up; FDR = 0.00737; PValue = 0.00165; mean CPM = 203.7; proteasome (prosome, macropain) subunit, beta type, 4" ID="ID_631748488" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMC6: 1.25-fold Up; FDR = 0.00969; PValue = 0.00227; mean CPM = 50.35; proteasome (prosome, macropain) 26S subunit, ATPase, 6" ID="ID_825763341" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPN2: 1.24-fold Down; FDR = 0.0118; PValue = 0.00285; mean CPM = 392.4; ribophorin II" ID="ID_1727811892" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMC2: 1.23-fold Up; FDR = 0.0127; PValue = 0.0031; mean CPM = 107.7; proteasome (prosome, macropain) 26S subunit, ATPase, 2" ID="ID_347150223" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="UBE2D2: 1.25-fold Up; FDR = 0.0128; PValue = 0.00312; mean CPM = 35.11; ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)" ID="ID_585608160" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="UBB: 1.22-fold Up; FDR = 0.0235; PValue = 0.00634; mean CPM = 526.7; ubiquitin B" ID="ID_286922049" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="H2AFZ: 1.3-fold Up; FDR = 0.0433; PValue = 0.013; mean CPM = 239.3; H2A histone family, member Z" ID="ID_547132181" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPN1: 1.2-fold Down; FDR = 0.0443; PValue = 0.0133; mean CPM = 385.0; ribophorin I" ID="ID_662516978" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="UCHL1: 1.33-fold Up; FDR = 0.0578; PValue = 0.0183; mean CPM = 437.6; ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)" ID="ID_1937181057" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMD7: 1.18-fold Up; FDR = 0.0606; PValue = 0.0193; mean CPM = 90.67; proteasome (prosome, macropain) 26S subunit, non-ATPase, 7" ID="ID_1460189926" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="UBE2B: 1.18-fold Up; FDR = 0.0712; PValue = 0.0234; mean CPM = 43.91; ubiquitin-conjugating enzyme E2B (RAD6 homolog)" ID="ID_982759782" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMD3: 1.17-fold Down; FDR = 0.0862; PValue = 0.0293; mean CPM = 144.8; proteasome (prosome, macropain) 26S subunit, non-ATPase, 3" ID="ID_230769072" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HIST1H2AB: 1.44-fold Down; FDR = 0.122; PValue = 0.0447; mean CPM = 27.61; histone cluster 1, H2ab" ID="ID_705148642" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMD9: 1.15-fold Up; FDR = 0.129; PValue = 0.0476; mean CPM = 64.87; proteasome (prosome, macropain) 26S subunit, non-ATPase, 9" ID="ID_402372410" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMB6: 1.15-fold Up; FDR = 0.129; PValue = 0.0478; mean CPM = 142.5; Proteasome subunit beta type" ID="ID_1897317953" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMC1: 1.14-fold Up; FDR = 0.154; PValue = 0.0595; mean CPM = 106.6; proteasome (prosome, macropain) 26S subunit, ATPase, 1" ID="ID_471129116" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMB3: 1.14-fold Up; FDR = 0.173; PValue = 0.0685; mean CPM = 101.4; proteasome (prosome, macropain) subunit, beta type, 3" ID="ID_1275869536" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMD12: 1.12-fold Up; FDR = 0.262; PValue = 0.115; mean CPM = 79.63; proteasome (prosome, macropain) 26S subunit, non-ATPase, 12" ID="ID_895919706" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMC5: 1.11-fold Down; FDR = 0.272; PValue = 0.12; mean CPM = 91.70; proteasome (prosome, macropain) 26S subunit, ATPase, 5" ID="ID_855451513" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMC4: 1.11-fold Down; FDR = 0.283; PValue = 0.125; mean CPM = 92.37; proteasome (prosome, macropain) 26S subunit, ATPase, 4" ID="ID_413186365" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMC3: 1.11-fold Down; FDR = 0.301; PValue = 0.136; mean CPM = 165.0; proteasome (prosome, macropain) 26S subunit, ATPase, 3" ID="ID_1516559676" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMD2: 1.11-fold Down; FDR = 0.343; PValue = 0.16; mean CPM = 262.0; proteasome (prosome, macropain) 26S subunit, non-ATPase, 2" ID="ID_819672629" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMD6: 1.1-fold Up; FDR = 0.367; PValue = 0.174; mean CPM = 108.1; 26S proteasome non-ATPase regulatory subunit 6; Uncharacterized protein" ID="ID_1253252137" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMD11: 1.08-fold Up; FDR = 0.501; PValue = 0.259; mean CPM = 87.50; proteasome (prosome, macropain) 26S subunit, non-ATPase, 11" ID="ID_718489677" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMB5: 1.07-fold Down; FDR = 0.575; PValue = 0.312; mean CPM = 166.1; proteasome (prosome, macropain) subunit, beta type, 5" ID="ID_322732382" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000029957: 1.36-fold Down; FDR = 0.65; PValue = 0.368; mean CPM = 1.099; Uncharacterized protein" ID="ID_1425596261" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMD13: 1.04-fold Up; FDR = 0.86; PValue = 0.575; mean CPM = 149.8; proteasome (prosome, macropain) 26S subunit, non-ATPase, 13" ID="ID_958831333" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMD5: 1.04-fold Up; FDR = 0.87; PValue = 0.587; mean CPM = 65.35; proteasome (prosome, macropain) 26S subunit, non-ATPase, 5" ID="ID_1905706203" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HIST1H2AE: 1.06-fold Down; FDR = 0.886; PValue = 0.607; mean CPM = 107.6; histone cluster 1, H2ae" ID="ID_823115353" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_1194821082" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMD8: 1.03-fold Down; FDR = 0.911; PValue = 0.695; mean CPM = 126.7; proteasome (prosome, macropain) 26S subunit, non-ATPase, 8" ID="ID_1349951967" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000039234: 1.28-fold Down; FDR = 0.963; PValue = 0.798; mean CPM = 0.8652; Uncharacterized protein" ID="ID_1808192322" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NEDD4: 1.01-fold Down; FDR = 1; PValue = 0.86; mean CPM = 49.99; neural precursor cell expressed, developmentally down-regulated 4" ID="ID_17802106" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSME3: No Change; FDR = 1; PValue = 0.946; mean CPM = 64.75; proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)" ID="ID_478598053" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-2 Signaling pathway (WP49:Rev45366): FDR = 6.05e-17, PValue = 3.78e-18" ID="ID_93739762" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="NMI: 6.35-fold Up; FDR = 1.04e-21; PValue = 2.78e-24; mean CPM = 42.95; N-myc (and STAT) interactor" ID="ID_987275645" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_657690533" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5A: 2.28-fold Up; FDR = 6.87e-14; PValue = 8.58e-16; mean CPM = 21.55; signal transducer and activator of transcription 5A" ID="ID_1531721315" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_81214907" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_1873673124" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2B: 3.54-fold Up; FDR = 1.24e-07; PValue = 7.07e-09; mean CPM = 5.971; PTK2B protein tyrosine kinase 2 beta" ID="ID_620135742" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_847448388" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_875228675" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPT: 2.89-fold Down; FDR = 3.14e-05; PValue = 3.34e-06; mean CPM = 2.105; microtubule-associated protein tau" ID="ID_1915819447" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB2: 1.38-fold Down; FDR = 4.66e-05; PValue = 5.24e-06; mean CPM = 61.90; ribosomal protein S6 kinase, 70kDa, polypeptide 2" ID="ID_540005238" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS3: 1.69-fold Up; FDR = 0.000994; PValue = 0.000167; mean CPM = 37.76; suppressor of cytokine signaling 3" ID="ID_130363093" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CISH: 1.95-fold Up; FDR = 0.00116; PValue = 0.0002; mean CPM = 5.083; cytokine inducible SH2-containing protein" ID="ID_133418341" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK3: 2.31-fold Up; FDR = 0.00186; PValue = 0.000342; mean CPM = 2.154; Janus kinase 3" ID="ID_1780102324" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GAB2: 1.33-fold Down; FDR = 0.00208; PValue = 0.000387; mean CPM = 22.59; GRB2-associated binding protein 2" ID="ID_797645686" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FYN: 1.22-fold Up; FDR = 0.0156; PValue = 0.00393; mean CPM = 92.94; FYN oncogene related to SRC, FGR, YES" ID="ID_524167586" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_20860302" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_65654381" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_330049074" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_1611405342" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_602601458" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_1710469941" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1350870317" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_188987431" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_452309979" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND2: 1.2-fold Up; FDR = 0.335; PValue = 0.155; mean CPM = 76.91; cyclin D2" ID="ID_992062544" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRKL: 1.11-fold Up; FDR = 0.371; PValue = 0.176; mean CPM = 34.10; v-crk sarcoma virus CT10 oncogene homolog (avian)-like" ID="ID_795898697" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2: 1.48-fold Up; FDR = 0.384; PValue = 0.184; mean CPM = 1.344; Uncharacterized protein" ID="ID_1237207492" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_817965731" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_1507679310" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOXO3: 1.08-fold Down; FDR = 0.55; PValue = 0.294; mean CPM = 48.45; forkhead box O3" ID="ID_16955554" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6: 1.08-fold Up; FDR = 0.584; PValue = 0.318; mean CPM = 892.5; ribosomal protein S6" ID="ID_258719010" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CBL: 1.05-fold Down; FDR = 0.824; PValue = 0.524; mean CPM = 51.06; Cas-Br-M (murine) ecotropic retroviral transforming sequence" ID="ID_1090177601" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1633952439" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB1: 1.04-fold Up; FDR = 0.88; PValue = 0.6; mean CPM = 30.80; Uncharacterized protein" ID="ID_1974306045" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2RA: 1.08-fold Up; FDR = 0.945; PValue = 0.766; mean CPM = 0.8493; interleukin 2 receptor, alpha" ID="ID_1362528138" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_1304999627" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SYK: 1.11-fold Up; FDR = 1; PValue = 0.977; mean CPM = 0.8420; spleen tyrosine kinase" ID="ID_364327203" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2: 1.03-fold Up; FDR = 1; PValue = 0.998; mean CPM = 0.7974; interleukin 2" ID="ID_494125346" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Folate Metabolism (WP176:Rev45271): FDR = 2.1e-16, PValue = 1.42e-17" ID="ID_73030862" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CSF1: 7.34-fold Up; FDR = 4.6e-20; PValue = 1.69e-22; mean CPM = 149.8; colony stimulating factor 1 (macrophage)" ID="ID_1442753645" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICAM1: 24.6-fold Up; FDR = 2.39e-17; PValue = 1.64e-19; mean CPM = 232.4; intercellular adhesion molecule 1" ID="ID_365109174" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL2: 24.6-fold Up; FDR = 1.83e-15; PValue = 1.69e-17; mean CPM = 668.2; Macaca mulatta chemokine (C-C motif) ligand 2 (CCL2), mRNA." ID="ID_956033587" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOD1: 1.67-fold Up; FDR = 3.83e-10; PValue = 1.17e-11; mean CPM = 160.0; superoxide dismutase 1, soluble" ID="ID_1534865859" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAT: 1.75-fold Up; FDR = 1.21e-09; PValue = 4.14e-11; mean CPM = 42.72; catalase" ID="ID_19001792" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INSR: 1.93-fold Down; FDR = 1.24e-08; PValue = 5.48e-10; mean CPM = 118.3; insulin receptor" ID="ID_1147690144" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOD2: 4.88-fold Up; FDR = 1.73e-08; PValue = 7.93e-10; mean CPM = 558.4; superoxide dismutase 2, mitochondrial" ID="ID_1082227424" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_13504955" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ABCA1: 2.65-fold Up; FDR = 5.3e-07; PValue = 3.52e-08; mean CPM = 203.4; ATP-binding cassette, sub-family A (ABC1), member 1" ID="ID_1896557793" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RFK: 2-fold Up; FDR = 1.24e-05; PValue = 1.19e-06; mean CPM = 7.534; riboflavin kinase" ID="ID_297994900" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTHFS: 1.7-fold Up; FDR = 8.32e-05; PValue = 1.01e-05; mean CPM = 7.979; 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)" ID="ID_1963105197" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_1506406640" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTRR: 1.38-fold Up; FDR = 0.000187; PValue = 2.52e-05; mean CPM = 32.85; 5-methyltetrahydrofolate-homocysteine methyltransferase reductase" ID="ID_873026244" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SCARB1: 1.44-fold Down; FDR = 0.000494; PValue = 7.55e-05; mean CPM = 14.81; scavenger receptor class B, member 1" ID="ID_1312948993" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SERPINE1: 1.58-fold Down; FDR = 0.00232; PValue = 0.000438; mean CPM = 5294; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1" ID="ID_764792071" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTHFD2: 1.37-fold Up; FDR = 0.00326; PValue = 0.000646; mean CPM = 158.6; methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase" ID="ID_660992827" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOD3: 1.7-fold Down; FDR = 0.00506; PValue = 0.00107; mean CPM = 36.72; superoxide dismutase 3, extracellular" ID="ID_560445447" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FLAD1: 1.27-fold Up; FDR = 0.00617; PValue = 0.00135; mean CPM = 31.00; Uncharacterized protein" ID="ID_1761911813" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTH: 1.72-fold Up; FDR = 0.00927; PValue = 0.00216; mean CPM = 23.63; cystathionase (cystathionine gamma-lyase)" ID="ID_1081161701" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLAT: 1.37-fold Down; FDR = 0.034; PValue = 0.00976; mean CPM = 76.44; plasminogen activator, tissue" ID="ID_482423753" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1030517126" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SERPINA3: 1.78-fold Down; FDR = 0.0544; PValue = 0.017; mean CPM = 6.499; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3" ID="ID_676840139" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTR: 1.18-fold Down; FDR = 0.0633; PValue = 0.0203; mean CPM = 75.25; 5-methyltetrahydrofolate-homocysteine methyltransferase" ID="ID_827942293" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APOA1: 2.5-fold Down; FDR = 0.104; PValue = 0.0368; mean CPM = 0.9574; apolipoprotein A-I" ID="ID_503368582" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="F2: 1.67-fold Down; FDR = 0.132; PValue = 0.0494; mean CPM = 1.475; coagulation factor II (thrombin)" ID="ID_814278796" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GART: 1.13-fold Up; FDR = 0.215; PValue = 0.0896; mean CPM = 54.95; phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase" ID="ID_218942287" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTHFR: 1.17-fold Down; FDR = 0.235; PValue = 0.1; mean CPM = 12.57; methylenetetrahydrofolate reductase (NAD(P)H)" ID="ID_1846069370" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP53: 1.11-fold Down; FDR = 0.364; PValue = 0.172; mean CPM = 33.25; tumor protein p53" ID="ID_1048040368" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOLR1: 1.58-fold Up; FDR = 0.49; PValue = 0.252; mean CPM = 0.9729; folate receptor 1 (adult)" ID="ID_1050253834" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC19A1: 1.13-fold Down; FDR = 0.615; PValue = 0.34; mean CPM = 10.02; solute carrier family 19 (folate transporter), member 1" ID="ID_205073752" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTHFD1: 1.09-fold Up; FDR = 0.646; PValue = 0.364; mean CPM = 60.07; Uncharacterized protein" ID="ID_721449173" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_1316278804" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHMT1: 1.18-fold Down; FDR = 0.679; PValue = 0.39; mean CPM = 2.898; serine hydroxymethyltransferase 1 (soluble)" ID="ID_578042422" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APOB: 1.36-fold Down; FDR = 0.723; PValue = 0.426; mean CPM = 0.9779; apolipoprotein B (including Ag(x) antigen)" ID="ID_709249236" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LDLR: 1.07-fold Down; FDR = 0.854; PValue = 0.567; mean CPM = 167.3; low density lipoprotein receptor" ID="ID_961841370" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOLR2: 1.25-fold Down; FDR = 0.88; PValue = 0.599; mean CPM = 0.9554; folate receptor 2 (fetal)" ID="ID_1277683899" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HBB: 1.21-fold Up; FDR = 0.883; PValue = 0.603; mean CPM = 0.9754; hemoglobin, beta" ID="ID_61516523" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_363092800" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_206863154" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAT1A: 1.31-fold Down; FDR = 0.903; PValue = 0.656; mean CPM = 0.8409; methionine adenosyltransferase I, alpha" ID="ID_1459949370" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="F7: 1.07-fold Down; FDR = 0.921; PValue = 0.723; mean CPM = 2.252; coagulation factor VII (serum prothrombin conversion accelerator)" ID="ID_1643145574" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HBA1: 1.14-fold Up; FDR = 0.929; PValue = 0.738; mean CPM = 0.8217; hemoglobin, alpha 1" ID="ID_713603663" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL4: 1.27-fold Down; FDR = 0.933; PValue = 0.745; mean CPM = 0.8077; interleukin 4" ID="ID_151896179" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLG: 1.41-fold Down; FDR = 0.937; PValue = 0.751; mean CPM = 0.8390; plasminogen" ID="ID_1918400955" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HBA2: 1.16-fold Up; FDR = 0.942; PValue = 0.76; mean CPM = 0.8111; hemoglobin, alpha 2" ID="ID_863089430" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC46A1: 1.06-fold Up; FDR = 0.951; PValue = 0.777; mean CPM = 3.272; solute carrier family 46 (folate transporter), member 1" ID="ID_1149725919" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ALB: 1.05-fold Down; FDR = 1; PValue = 0.98; mean CPM = 0.8186; Serum albumin" ID="ID_111306365" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2: 1.03-fold Up; FDR = 1; PValue = 0.998; mean CPM = 0.7974; interleukin 2" ID="ID_535357912" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRP: No Change; FDR = 1; PValue = 1; mean CPM = 0.7818; Uncharacterized protein" ID="ID_1645648784" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Apoptosis (WP254:Rev41184): FDR = 1.14e-15, PValue = 8.33e-17" ID="ID_1121952451" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="IRF1: 18.6-fold Up; FDR = 1.53e-21; PValue = 4.24e-24; mean CPM = 240.7; interferon regulatory factor 1" ID="ID_1733099610" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF2: 3.25-fold Up; FDR = 2.61e-18; PValue = 1.48e-20; mean CPM = 32.37; interferon regulatory factor 2" ID="ID_1679751735" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF7: 14.8-fold Up; FDR = 7.66e-18; PValue = 4.82e-20; mean CPM = 11.54; Macaca mulatta interferon regulatory factor 7 (IRF7), mRNA." ID="ID_724079133" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_1668791501" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF10: 44.5-fold Up; FDR = 2.83e-16; PValue = 2.4e-18; mean CPM = 6.029; Tumor necrosis factor ligand superfamily member 10 isoform 1; Uncharacterized protein" ID="ID_353206179" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PMAIP1: 8.66-fold Up; FDR = 1.12e-12; PValue = 1.84e-14; mean CPM = 31.02; Phorbol-12-myristate-13-acetate-induced protein 1; Uncharacterized protein" ID="ID_1561925063" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP4: 4.99-fold Up; FDR = 6.91e-12; PValue = 1.4e-13; mean CPM = 56.06; Caspase" ID="ID_808358291" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC2: 1.96-fold Up; FDR = 1.01e-10; PValue = 2.62e-12; mean CPM = 53.58; baculoviral IAP repeat-containing 2" ID="ID_1376056752" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CFLAR: 1.87-fold Up; FDR = 5.09e-10; PValue = 1.61e-11; mean CPM = 103.3; CASP8 and FADD-like apoptosis regulator" ID="ID_555154308" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BID: 1.66-fold Up; FDR = 5.41e-09; PValue = 2.19e-10; mean CPM = 35.19; BH3 interacting domain death agonist" ID="ID_355341180" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_1797490061" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1757520847" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_335484423" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L1: 1.51-fold Up; FDR = 9.13e-07; PValue = 6.52e-08; mean CPM = 66.15; Bcl-2-like protein 1; Bcl-2-like protein 1 isoform 1; Uncharacterized protein" ID="ID_336979687" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC3: 2.79-fold Up; FDR = 1.74e-06; PValue = 1.32e-07; mean CPM = 95.34; baculoviral IAP repeat-containing 3" ID="ID_363856647" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1B: 2.24-fold Up; FDR = 2.68e-06; PValue = 2.16e-07; mean CPM = 19.44; tumor necrosis factor receptor superfamily, member 1B" ID="ID_1445359489" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1: 5.76-fold Down; FDR = 6.73e-06; PValue = 6.04e-07; mean CPM = 1.536; insulin-like growth factor 1 (somatomedin C)" ID="ID_1787246570" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1R: 1.51-fold Down; FDR = 1.02e-05; PValue = 9.61e-07; mean CPM = 213.2; insulin-like growth factor 1 receptor" ID="ID_1385937576" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BNIP3L: 1.42-fold Up; FDR = 1.15e-05; PValue = 1.09e-06; mean CPM = 219.7; BCL2/adenovirus E1B 19kDa interacting protein 3-like" ID="ID_1989771550" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF1: 2.6-fold Down; FDR = 1.48e-05; PValue = 1.46e-06; mean CPM = 20.19; TNF receptor-associated factor 1" ID="ID_34488063" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_10179218" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAD: 1.36-fold Down; FDR = 0.000605; PValue = 9.52e-05; mean CPM = 48.46; BCL2-associated agonist of cell death" ID="ID_357465942" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_106672318" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MDM2: 1.32-fold Up; FDR = 0.00555; PValue = 0.00119; mean CPM = 148.6; Uncharacterized protein" ID="ID_1049392285" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_1439563971" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP10: 1.81-fold Up; FDR = 0.0175; PValue = 0.0045; mean CPM = 2.876; caspase 10, apoptosis-related cysteine peptidase" ID="ID_447976302" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1411875257" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIE: 1.3-fold Down; FDR = 0.0272; PValue = 0.00752; mean CPM = 16.93; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon" ID="ID_538865280" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRADD: 1.22-fold Up; FDR = 0.0319; PValue = 0.00907; mean CPM = 34.75; TNFRSF1A-associated via death domain" ID="ID_127498253" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MCL1: 1.2-fold Up; FDR = 0.0335; PValue = 0.00961; mean CPM = 193.8; myeloid cell leukemia sequence 1 (BCL2-related)" ID="ID_1135889208" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1452236433" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP63: 1.81-fold Down; FDR = 0.0567; PValue = 0.0179; mean CPM = 2.228; tumor protein p63" ID="ID_1300096726" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP73: 2.3-fold Down; FDR = 0.0601; PValue = 0.0192; mean CPM = 1.058; tumor protein p73" ID="ID_695299632" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L11: 1.34-fold Up; FDR = 0.0609; PValue = 0.0195; mean CPM = 18.38; BCL2-like 11 (apoptosis facilitator)" ID="ID_1897972187" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DFFA: 1.18-fold Down; FDR = 0.0688; PValue = 0.0225; mean CPM = 44.03; DNA fragmentation factor, 45kDa, alpha polypeptide" ID="ID_1020555150" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_1269000449" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DIABLO: 1.17-fold Up; FDR = 0.0849; PValue = 0.0288; mean CPM = 58.69; diablo homolog (Drosophila)" ID="ID_408957209" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FADD: 1.18-fold Down; FDR = 0.0936; PValue = 0.0324; mean CPM = 30.89; Uncharacterized protein" ID="ID_816772469" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_1434773818" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF4: 2.95-fold Down; FDR = 0.124; PValue = 0.0456; mean CPM = 0.9773; interferon regulatory factor 4" ID="ID_1017011513" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC5: 1.51-fold Down; FDR = 0.134; PValue = 0.0501; mean CPM = 18.55; Baculoviral IAP repeat-containing protein 5 isoform 1; Uncharacterized protein" ID="ID_941355216" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1600139357" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XIAP: 1.17-fold Up; FDR = 0.177; PValue = 0.0706; mean CPM = 19.21; X-linked inhibitor of apoptosis" ID="ID_450569653" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP6: 1.17-fold Up; FDR = 0.197; PValue = 0.0807; mean CPM = 14.25; caspase 6, apoptosis-related cysteine peptidase" ID="ID_567772380" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP7: 1.15-fold Up; FDR = 0.218; PValue = 0.0916; mean CPM = 21.49; caspase 7, apoptosis-related cysteine peptidase" ID="ID_1961856451" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000039103: 1.67-fold Down; FDR = 0.221; PValue = 0.0927; mean CPM = 1.310; Uncharacterized protein" ID="ID_1319711346" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1A: 1.11-fold Up; FDR = 0.297; PValue = 0.134; mean CPM = 134.7; tumor necrosis factor receptor superfamily, member 1A" ID="ID_1910917606" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HELLS: 1.19-fold Down; FDR = 0.331; PValue = 0.153; mean CPM = 21.44; Uncharacterized protein" ID="ID_1619392646" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF10B: 1.13-fold Down; FDR = 0.343; PValue = 0.16; mean CPM = 40.59; tumor necrosis factor receptor superfamily, member 10b" ID="ID_990184690" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP53: 1.11-fold Down; FDR = 0.364; PValue = 0.172; mean CPM = 33.25; tumor protein p53" ID="ID_642048431" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF2: 1.42-fold Up; FDR = 0.383; PValue = 0.183; mean CPM = 31.20; insulin-like growth factor 2 (somatomedin A)" ID="ID_1977733908" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2: 1.48-fold Up; FDR = 0.384; PValue = 0.184; mean CPM = 1.344; Uncharacterized protein" ID="ID_499096376" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BOK: 1.12-fold Down; FDR = 0.416; PValue = 0.204; mean CPM = 14.21; BCL2-related ovarian killer" ID="ID_127284430" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF6: 2.34-fold Down; FDR = 0.535; PValue = 0.283; mean CPM = 0.8609; interferon regulatory factor 6" ID="ID_53684839" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L2: 1.08-fold Down; FDR = 0.578; PValue = 0.314; mean CPM = 35.23; BCL2-like 2" ID="ID_698821524" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF3: 1.07-fold Up; FDR = 0.611; PValue = 0.338; mean CPM = 34.56; TNF receptor-associated factor 3" ID="ID_1199920677" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_185716285" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF25: 1.2-fold Up; FDR = 0.772; PValue = 0.471; mean CPM = 1.687; tumor necrosis factor receptor superfamily, member 25" ID="ID_466839837" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAX: 1.05-fold Up; FDR = 0.809; PValue = 0.506; mean CPM = 162.4; Uncharacterized protein" ID="ID_855546013" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRADD: 1.1-fold Down; FDR = 0.827; PValue = 0.527; mean CPM = 3.992; CASP2 and RIPK1 domain containing adaptor with death domain" ID="ID_1702561561" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GZMB: 1.43-fold Up; FDR = 0.83; PValue = 0.532; mean CPM = 0.7972; granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)" ID="ID_1364718391" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APAF1: 1.05-fold Down; FDR = 0.837; PValue = 0.543; mean CPM = 32.11; apoptotic peptidase activating factor 1" ID="ID_1993321350" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRF1: 1.75-fold Up; FDR = 0.841; PValue = 0.548; mean CPM = 0.8583; perforin 1 (pore forming protein)" ID="ID_158541978" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF5: 1.06-fold Down; FDR = 0.85; PValue = 0.561; mean CPM = 9.280; interferon regulatory factor 5" ID="ID_1051793931" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYCS: 1.05-fold Up; FDR = 0.854; PValue = 0.565; mean CPM = 93.43; cytochrome c, somatic" ID="ID_340311634" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1649996333" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000040219: 1.08-fold Up; FDR = 0.86; PValue = 0.575; mean CPM = 8.818; Uncharacterized protein" ID="ID_49599082" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_1422302639" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP2: 1.05-fold Up; FDR = 0.906; PValue = 0.667; mean CPM = 12.88; caspase 2, apoptosis-related cysteine peptidase" ID="ID_1832143859" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DFFB: 1.05-fold Down; FDR = 0.911; PValue = 0.699; mean CPM = 5.555; DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)" ID="ID_850263397" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF21: 1.07-fold Down; FDR = 0.922; PValue = 0.726; mean CPM = 6.488; tumor necrosis factor receptor superfamily, member 21" ID="ID_1343729267" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FASLG: 1.2-fold Down; FDR = 0.941; PValue = 0.757; mean CPM = 0.8088; Fas ligand (TNF superfamily, member 6)" ID="ID_189673786" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BBC3: 1.04-fold Down; FDR = 0.948; PValue = 0.77; mean CPM = 7.586; BCL2 binding component 3" ID="ID_1675346825" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000009289: 1.07-fold Up; FDR = 0.963; PValue = 0.798; mean CPM = 2.536; Uncharacterized protein" ID="ID_1287634955" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_534117727" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP9: 1.01-fold Up; FDR = 1; PValue = 0.908; mean CPM = 19.86; caspase 9, apoptosis-related cysteine peptidase" ID="ID_1265091281" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_979303262" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Inflammatory Response Pathway (WP453:Rev41201): FDR = 1.59e-15, PValue = 1.24e-16" ID="ID_1487535879" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="COL3A1: 20.5-fold Down; FDR = 5.71e-15; PValue = 5.82e-17; mean CPM = 5961; collagen, type III, alpha 1" ID="ID_1770014453" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL1A1: 21.5-fold Down; FDR = 1.13e-13; PValue = 1.5e-15; mean CPM = 15389; collagen, type I, alpha 1" ID="ID_1546905091" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL1A2: 10.7-fold Down; FDR = 3.82e-13; PValue = 5.68e-15; mean CPM = 17923; collagen, type I, alpha 2" ID="ID_819896694" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMC1: 2.28-fold Down; FDR = 6.46e-13; PValue = 1.01e-14; mean CPM = 812.1; laminin, gamma 1 (formerly LAMB2)" ID="ID_1148803335" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016591: 4.2-fold Down; FDR = 1.3e-11; PValue = 2.78e-13; mean CPM = 34.90; Uncharacterized protein" ID="ID_1974205888" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016587: 4.92-fold Down; FDR = 1.6e-11; PValue = 3.5e-13; mean CPM = 51.70; Uncharacterized protein" ID="ID_603822457" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THBS3: 1.97-fold Up; FDR = 7.19e-08; PValue = 3.88e-09; mean CPM = 128.6; thrombospondin 3" ID="ID_1455438926" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THBS1: 2.74-fold Down; FDR = 1.68e-06; PValue = 1.28e-07; mean CPM = 25785; thrombospondin 1" ID="ID_252404632" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1B: 2.24-fold Up; FDR = 2.68e-06; PValue = 2.16e-07; mean CPM = 19.44; tumor necrosis factor receptor superfamily, member 1B" ID="ID_670521322" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMC2: 2.28-fold Down; FDR = 9.83e-06; PValue = 9.24e-07; mean CPM = 16.99; laminin, gamma 2" ID="ID_1548111770" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40: 2.76-fold Up; FDR = 0.00039; PValue = 5.79e-05; mean CPM = 9.139; CD40 molecule, TNF receptor superfamily member 5" ID="ID_1878488788" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB2: 1.48-fold Down; FDR = 0.000398; PValue = 5.93e-05; mean CPM = 695.6; laminin, beta 2 (laminin S)" ID="ID_1983973738" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FN1: 1.7-fold Down; FDR = 0.0164; PValue = 0.00417; mean CPM = 40317; fibronectin 1" ID="ID_1484384851" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1A: 1.11-fold Up; FDR = 0.297; PValue = 0.134; mean CPM = 134.7; tumor necrosis factor receptor superfamily, member 1A" ID="ID_288627414" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VTN: 1.19-fold Up; FDR = 0.669; PValue = 0.382; mean CPM = 2.950; vitronectin" ID="ID_1519507951" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL4R: 1.05-fold Down; FDR = 0.803; PValue = 0.499; mean CPM = 193.5; interleukin 4 receptor" ID="ID_1704110663" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZAP70: 1.25-fold Down; FDR = 0.872; PValue = 0.59; mean CPM = 0.8996; zeta-chain (TCR) associated protein kinase 70kDa" ID="ID_1909882009" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_723906379" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL4: 1.27-fold Down; FDR = 0.933; PValue = 0.745; mean CPM = 0.8077; interleukin 4" ID="ID_770918859" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2RA: 1.08-fold Up; FDR = 0.945; PValue = 0.766; mean CPM = 0.8493; interleukin 2 receptor, alpha" ID="ID_1933287299" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL5RA: 1.1-fold Up; FDR = 0.958; PValue = 0.791; mean CPM = 0.8108; interleukin 5 receptor, alpha" ID="ID_1720323455" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD80: 1.08-fold Up; FDR = 0.971; PValue = 0.812; mean CPM = 1.157; CD80 molecule" ID="ID_344494794" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL5: 1.05-fold Down; FDR = 1; PValue = 0.862; mean CPM = 1.367; interleukin 5 (colony-stimulating factor, eosinophil)" ID="ID_1800689848" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40LG: 1.01-fold Down; FDR = 1; PValue = 0.982; mean CPM = 0.8653; CD40 ligand" ID="ID_996099153" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD86: 1.01-fold Down; FDR = 1; PValue = 0.99; mean CPM = 0.8012; CD86 molecule" ID="ID_1720261706" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2: 1.03-fold Up; FDR = 1; PValue = 0.998; mean CPM = 0.7974; interleukin 2" ID="ID_720633438" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Tryptophan metabolism (WP465:Rev45056): FDR = 1.04e-14, PValue = 9.06e-16" ID="ID_462846455" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="WARS: 18.8-fold Up; FDR = 1.64e-26; PValue = 6.18e-30; mean CPM = 1926; Uncharacterized protein" ID="ID_7550766" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ALDH3A2: 2.28-fold Up; FDR = 3.87e-11; PValue = 9.34e-13; mean CPM = 141.3; aldehyde dehydrogenase 3 family, member A2" ID="ID_725137250" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAT: 1.75-fold Up; FDR = 1.21e-09; PValue = 4.14e-11; mean CPM = 42.72; catalase" ID="ID_1871294356" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYP7B1: 2.51-fold Up; FDR = 7.19e-07; PValue = 4.96e-08; mean CPM = 4.335; cytochrome P450, family 7, subfamily B, polypeptide 1" ID="ID_244800812" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DHCR24: 4.93-fold Down; FDR = 1.5e-06; PValue = 1.12e-07; mean CPM = 2.190; 24-dehydrocholesterol reductase" ID="ID_174689986" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TDO2: 5.53-fold Down; FDR = 9.15e-06; PValue = 8.53e-07; mean CPM = 1.291; tryptophan 2,3-dioxygenase" ID="ID_1402215553" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ALDH9A1: 1.39-fold Up; FDR = 3.68e-05; PValue = 4e-06; mean CPM = 71.34; aldehyde dehydrogenase 9 family, member A1" ID="ID_1160135182" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ALDH2: 1.44-fold Down; FDR = 5.61e-05; PValue = 6.45e-06; mean CPM = 99.09; aldehyde dehydrogenase 2 family (mitochondrial)" ID="ID_599025908" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AFMID: 2.19-fold Down; FDR = 7e-05; PValue = 8.32e-06; mean CPM = 3.683; arylformamidase" ID="ID_33506020" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KYNU: 1.76-fold Up; FDR = 0.000177; PValue = 2.37e-05; mean CPM = 157.2; kynureninase (L-kynurenine hydrolase)" ID="ID_276447541" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AOX1: 1.42-fold Up; FDR = 0.00238; PValue = 0.000452; mean CPM = 201.8; aldehyde oxidase 1" ID="ID_1121223940" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACAT1: 1.35-fold Down; FDR = 0.00247; PValue = 0.000471; mean CPM = 32.72; acetyl-CoA acetyltransferase 1" ID="ID_345738942" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ALDH1A2: 1.81-fold Down; FDR = 0.00471; PValue = 0.000992; mean CPM = 17.58; aldehyde dehydrogenase 1 family, member A2" ID="ID_1123302509" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GCDH: 1.32-fold Down; FDR = 0.00538; PValue = 0.00115; mean CPM = 17.15; glutaryl-CoA dehydrogenase" ID="ID_911948611" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MDM2: 1.32-fold Up; FDR = 0.00555; PValue = 0.00119; mean CPM = 148.6; Uncharacterized protein" ID="ID_875179107" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYP1B1: 1.38-fold Down; FDR = 0.0201; PValue = 0.00528; mean CPM = 273.1; cytochrome P450, family 1, subfamily B, polypeptide 1" ID="ID_725566019" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DDC: 3.34-fold Down; FDR = 0.023; PValue = 0.00617; mean CPM = 0.9003; dopa decarboxylase (aromatic L-amino acid decarboxylase)" ID="ID_1975210023" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYP2J2: 2.77-fold Up; FDR = 0.0309; PValue = 0.00873; mean CPM = 1.048; cytochrome P450, family 2, subfamily J, polypeptide 2" ID="ID_1157837330" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYP2A13: 2.01-fold Up; FDR = 0.0381; PValue = 0.0112; mean CPM = 1.749; cytochrome P450, family 2, subfamily A, polypeptide 13" ID="ID_517484195" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYP19A1: 2-fold Down; FDR = 0.0384; PValue = 0.0113; mean CPM = 1.909; cytochrome P450, family 19, subfamily A, polypeptide 1" ID="ID_836876005" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAOB: 1.82-fold Down; FDR = 0.116; PValue = 0.0418; mean CPM = 1.532; monoamine oxidase B" ID="ID_1636977807" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="UBE3A: 1.2-fold Down; FDR = 0.117; PValue = 0.0423; mean CPM = 14.75; Ubiquitin-protein ligase E3A isoform 3; Uncharacterized protein" ID="ID_1466091855" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACMSD: 2.19-fold Down; FDR = 0.14; PValue = 0.0529; mean CPM = 0.9416; aminocarboxymuconate semialdehyde decarboxylase" ID="ID_430891805" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYP2F1: 1.24-fold Down; FDR = 0.229; PValue = 0.0971; mean CPM = 5.289; cytochrome P450, family 2, subfamily F, polypeptide 1" ID="ID_764720300" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="UBE3A: 1.12-fold Down; FDR = 0.245; PValue = 0.105; mean CPM = 67.15; ubiquitin protein ligase E3A" ID="ID_30443769" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRMT1: 1.11-fold Down; FDR = 0.34; PValue = 0.158; mean CPM = 156.5; protein arginine methyltransferase 1" ID="ID_344778296" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="UBR5: 1.1-fold Down; FDR = 0.4; PValue = 0.194; mean CPM = 515.4; ubiquitin protein ligase E3 component n-recognin 5" ID="ID_412176747" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HADH: 1.1-fold Up; FDR = 0.419; PValue = 0.205; mean CPM = 32.14; hydroxyacyl-CoA dehydrogenase" ID="ID_1995528268" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ALDH1A1: 1.23-fold Down; FDR = 0.628; PValue = 0.351; mean CPM = 4.599; aldehyde dehydrogenase 1 family, member A1" ID="ID_1096383334" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYP1A1: 1.35-fold Up; FDR = 0.658; PValue = 0.373; mean CPM = 1.117; cytochrome P450, family 1, subfamily A, polypeptide 1" ID="ID_1761318840" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYP4F12: 1.46-fold Down; FDR = 0.698; PValue = 0.406; mean CPM = 1.446; cytochrome P450, family 4, subfamily F, polypeptide 12" ID="ID_1515496088" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSD17B10: 1.06-fold Down; FDR = 0.735; PValue = 0.437; mean CPM = 95.79; hydroxysteroid (17-beta) dehydrogenase 10" ID="ID_947951498" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RNF25: 1.06-fold Down; FDR = 0.747; PValue = 0.447; mean CPM = 22.86; ring finger protein 25" ID="ID_561164212" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYP2C18: 1.22-fold Up; FDR = 0.909; PValue = 0.687; mean CPM = 0.8257; Cytochrome P450 2C18; Uncharacterized protein" ID="ID_431566911" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ASMT: 1.14-fold Up; FDR = 0.911; PValue = 0.701; mean CPM = 0.7932; Macaca mulatta hydroxyindole O-methyltransferase (HIOMT), mRNA." ID="ID_986410380" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AANAT: 1.07-fold Up; FDR = 1; PValue = 0.869; mean CPM = 0.9312; aralkylamine N-acetyltransferase" ID="ID_264334877" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HAAO: 1.06-fold Up; FDR = 1; PValue = 0.87; mean CPM = 0.9953; 3-hydroxyanthranilate 3,4-dioxygenase" ID="ID_180043905" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ECHS1: 1.01-fold Up; FDR = 1; PValue = 0.885; mean CPM = 49.79; enoyl CoA hydratase, short chain, 1, mitochondrial" ID="ID_528516292" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYP1A2: 1.1-fold Up; FDR = 1; PValue = 0.958; mean CPM = 0.8552; cytochrome P450, family 1, subfamily A, polypeptide 2" ID="ID_1251937739" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INMT: 1.05-fold Down; FDR = 1; PValue = 0.989; mean CPM = 0.7994; indolethylamine N-methyltransferase" ID="ID_803197379" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYP2E1: No Change; FDR = 1; PValue = 0.995; mean CPM = 0.8039; cytochrome P450, family 2, subfamily E, polypeptide 1" ID="ID_364012067" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Serotonin Transporter Activity (WP1455:Rev45033): FDR = 1.04e-14, PValue = 9.23e-16" ID="ID_547170344" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="ITGB3: 5.02-fold Down; FDR = 1.72e-09; PValue = 6.17e-11; mean CPM = 43.21; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)" ID="ID_1341431242" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB1I1: 1.86-fold Down; FDR = 2.06e-08; PValue = 9.7e-10; mean CPM = 130.1; Uncharacterized protein" ID="ID_723456012" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SCAMP2: 1.5-fold Down; FDR = 2.72e-07; PValue = 1.69e-08; mean CPM = 69.29; secretory carrier membrane protein 2" ID="ID_759553889" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2CB: 1.35-fold Up; FDR = 0.000215; PValue = 2.96e-05; mean CPM = 59.68; protein phosphatase 2, catalytic subunit, beta isozyme" ID="ID_298951417" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C17orf57: 5.51-fold Down; FDR = 0.000238; PValue = 3.33e-05; mean CPM = 1.571; EF-hand domain-containing protein C17orf57" ID="ID_968214308" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STX1A: 1.45-fold Down; FDR = 0.00178; PValue = 0.000326; mean CPM = 10.16; syntaxin 1A (brain)" ID="ID_170392883" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAOA: 1.43-fold Down; FDR = 0.00532; PValue = 0.00114; mean CPM = 367.7; monoamine oxidase A" ID="ID_1912802234" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC6A4: 1.75-fold Down; FDR = 0.374; PValue = 0.178; mean CPM = 0.9214; Macaca mulatta solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 (SLC6A4), mRNA." ID="ID_1471422510" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_1804375341" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Focal Adhesion (WP306:Rev45270): FDR = 1.51e-14, PValue = 1.42e-15" ID="ID_57052411" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="COL4A1: 7.03-fold Down; FDR = 1.47e-15; PValue = 1.34e-17; mean CPM = 3419; collagen, type IV, alpha 1" ID="ID_1357188660" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL5A1: 4.69-fold Down; FDR = 3.09e-15; PValue = 2.99e-17; mean CPM = 1718; collagen, type V, alpha 1" ID="ID_656815432" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL3A1: 20.5-fold Down; FDR = 5.71e-15; PValue = 5.82e-17; mean CPM = 5961; collagen, type III, alpha 1" ID="ID_950203170" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL11A1: 12.2-fold Down; FDR = 8.67e-15; PValue = 9.24e-17; mean CPM = 318.0; collagen, type XI, alpha 1" ID="ID_1406181351" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA5: 3.79-fold Down; FDR = 1.33e-14; PValue = 1.48e-16; mean CPM = 1237; integrin, alpha 5 (fibronectin receptor, alpha polypeptide)" ID="ID_492971208" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFRA: 2.76-fold Up; FDR = 3.93e-14; PValue = 4.67e-16; mean CPM = 492.9; platelet-derived growth factor receptor, alpha polypeptide" ID="ID_1277140165" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL1A1: 21.5-fold Down; FDR = 1.13e-13; PValue = 1.5e-15; mean CPM = 15389; collagen, type I, alpha 1" ID="ID_1983152410" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VEGFC: 2-fold Up; FDR = 1.3e-13; PValue = 1.76e-15; mean CPM = 238.4; Macaca mulatta vascular endothelial growth factor C (VEGFC), mRNA." ID="ID_482203113" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHOB: 2.87-fold Down; FDR = 2.74e-13; PValue = 3.96e-15; mean CPM = 84.32; ras homolog gene family, member B" ID="ID_1680220020" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MET: 2.57-fold Up; FDR = 3.56e-13; PValue = 5.22e-15; mean CPM = 242.4; Macaca mulatta met proto-oncogene (hepatocyte growth factor receptor) (MET), mRNA." ID="ID_1143667256" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL1A2: 10.7-fold Down; FDR = 3.82e-13; PValue = 5.68e-15; mean CPM = 17923; collagen, type I, alpha 2" ID="ID_1418814032" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VCL: 2.48-fold Down; FDR = 5.94e-13; PValue = 9.16e-15; mean CPM = 1013; vinculin" ID="ID_1748697230" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMC1: 2.28-fold Down; FDR = 6.46e-13; PValue = 1.01e-14; mean CPM = 812.1; laminin, gamma 1 (formerly LAMB2)" ID="ID_557529426" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016591: 4.2-fold Down; FDR = 1.3e-11; PValue = 2.78e-13; mean CPM = 34.90; Uncharacterized protein" ID="ID_479887363" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016587: 4.92-fold Down; FDR = 1.6e-11; PValue = 3.5e-13; mean CPM = 51.70; Uncharacterized protein" ID="ID_940277540" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAV: 2.64-fold Down; FDR = 6.04e-11; PValue = 1.51e-12; mean CPM = 337.3; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)" ID="ID_1616710063" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND3: 2.27-fold Down; FDR = 8.38e-11; PValue = 2.15e-12; mean CPM = 86.90; cyclin D3" ID="ID_1473760752" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC2: 1.96-fold Up; FDR = 1.01e-10; PValue = 2.62e-12; mean CPM = 53.58; baculoviral IAP repeat-containing 2" ID="ID_806727514" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL5A3: 5.21-fold Down; FDR = 1.78e-10; PValue = 4.98e-12; mean CPM = 79.70; collagen, type V, alpha 3" ID="ID_887574303" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THBS2: 6.46-fold Down; FDR = 3.61e-10; PValue = 1.1e-11; mean CPM = 199.9; thrombospondin 2" ID="ID_1088763107" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB8: 3.97-fold Up; FDR = 6.37e-10; PValue = 2.06e-11; mean CPM = 11.37; integrin, beta 8" ID="ID_1240506227" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA2: 2.84-fold Up; FDR = 7.38e-10; PValue = 2.42e-11; mean CPM = 176.3; integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)" ID="ID_816691097" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB3: 5.02-fold Down; FDR = 1.72e-09; PValue = 6.17e-11; mean CPM = 43.21; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)" ID="ID_721605388" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL5A2: 2.25-fold Down; FDR = 2.26e-09; PValue = 8.27e-11; mean CPM = 2999; collagen, type V, alpha 2" ID="ID_1536115722" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_1846435923" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGFR: 1.84-fold Up; FDR = 6.71e-09; PValue = 2.77e-10; mean CPM = 68.58; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)" ID="ID_294716938" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB5: 1.61-fold Down; FDR = 8.23e-09; PValue = 3.47e-10; mean CPM = 471.0; integrin, beta 5" ID="ID_1891150750" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA10: 4.95-fold Down; FDR = 1.77e-08; PValue = 8.13e-10; mean CPM = 5.184; integrin, alpha 10" ID="ID_982297178" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FLNA: 2.35-fold Down; FDR = 2.01e-08; PValue = 9.45e-10; mean CPM = 7159; filamin A, alpha" ID="ID_1262662529" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TESK2: 4.45-fold Up; FDR = 3.77e-08; PValue = 1.9e-09; mean CPM = 7.759; testis-specific kinase 2" ID="ID_278897846" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA8: 4.04-fold Down; FDR = 5.89e-08; PValue = 3.12e-09; mean CPM = 145.8; integrin, alpha 8" ID="ID_171892958" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ILK: 1.53-fold Down; FDR = 5.97e-08; PValue = 3.17e-09; mean CPM = 256.9; integrin-linked kinase" ID="ID_1288832491" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THBS3: 1.97-fold Up; FDR = 7.19e-08; PValue = 3.88e-09; mean CPM = 128.6; thrombospondin 3" ID="ID_788505279" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COMP: 4.64-fold Down; FDR = 7.47e-08; PValue = 4.04e-09; mean CPM = 13.27; cartilage oligomeric matrix protein" ID="ID_361770111" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1B: 1.55-fold Up; FDR = 2.39e-07; PValue = 1.46e-08; mean CPM = 135.3; Ras-related protein Rap-1b; Ras-related protein Rap-1b isoform 1; Uncharacterized protein" ID="ID_228686953" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFA: 1.92-fold Down; FDR = 2.56e-07; PValue = 1.58e-08; mean CPM = 22.99; platelet-derived growth factor alpha polypeptide" ID="ID_680148510" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNC: 1.97-fold Down; FDR = 4.07e-07; PValue = 2.63e-08; mean CPM = 2667; tenascin C" ID="ID_187263069" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1805014864" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYLK: 2.29-fold Down; FDR = 1.02e-06; PValue = 7.45e-08; mean CPM = 128.3; myosin light chain kinase" ID="ID_988862740" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1401521157" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_333123699" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THBS1: 2.74-fold Down; FDR = 1.68e-06; PValue = 1.28e-07; mean CPM = 25785; thrombospondin 1" ID="ID_440384458" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC3: 2.79-fold Up; FDR = 1.74e-06; PValue = 1.32e-07; mean CPM = 95.34; baculoviral IAP repeat-containing 3" ID="ID_405366898" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_183141071" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC3: 1.68-fold Down; FDR = 2.72e-06; PValue = 2.19e-07; mean CPM = 13.98; ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)" ID="ID_888766925" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1: 5.76-fold Down; FDR = 6.73e-06; PValue = 6.04e-07; mean CPM = 1.536; insulin-like growth factor 1 (somatomedin C)" ID="ID_1249451977" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K3: 1.45-fold Down; FDR = 7.01e-06; PValue = 6.34e-07; mean CPM = 180.1; mitogen-activated protein kinase kinase 3" ID="ID_1650428247" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMC2: 2.28-fold Down; FDR = 9.83e-06; PValue = 9.24e-07; mean CPM = 16.99; laminin, gamma 2" ID="ID_880781039" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1R: 1.51-fold Down; FDR = 1.02e-05; PValue = 9.61e-07; mean CPM = 213.2; insulin-like growth factor 1 receptor" ID="ID_651665913" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1713780568" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYL6: 1.52-fold Down; FDR = 1.71e-05; PValue = 1.71e-06; mean CPM = 587.5; myosin, light chain 6, alkali, smooth muscle and non-muscle" ID="ID_685025344" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNK2: 1.75-fold Down; FDR = 3.26e-05; PValue = 3.5e-06; mean CPM = 44.07; tyrosine kinase, non-receptor, 2" ID="ID_1570568765" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K5: 1.55-fold Up; FDR = 7.6e-05; PValue = 9.12e-06; mean CPM = 16.82; mitogen-activated protein kinase kinase 5" ID="ID_826776511" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPP1: 2.25-fold Down; FDR = 7.74e-05; PValue = 9.29e-06; mean CPM = 35.33; secreted phosphoprotein 1" ID="ID_1883652773" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARHGAP5: 1.36-fold Up; FDR = 0.000133; PValue = 1.7e-05; mean CPM = 130.2; Rho GTPase activating protein 5" ID="ID_831384416" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCAR1: 1.36-fold Up; FDR = 0.000193; PValue = 2.61e-05; mean CPM = 210.4; breast cancer anti-estrogen resistance 1" ID="ID_856186938" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C17orf57: 5.51-fold Down; FDR = 0.000238; PValue = 3.33e-05; mean CPM = 1.571; EF-hand domain-containing protein C17orf57" ID="ID_1541395262" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL6A2: 1.47-fold Down; FDR = 0.000287; PValue = 4.1e-05; mean CPM = 1544; collagen, type VI, alpha 2" ID="ID_429349139" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HGF: 1.85-fold Down; FDR = 0.000377; PValue = 5.58e-05; mean CPM = 137.4; hepatocyte growth factor (hepapoietin A; scatter factor)" ID="ID_1222989129" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB2: 1.48-fold Down; FDR = 0.000398; PValue = 5.93e-05; mean CPM = 695.6; laminin, beta 2 (laminin S)" ID="ID_664933488" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA3: 1.34-fold Down; FDR = 0.000518; PValue = 7.96e-05; mean CPM = 126.8; integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)" ID="ID_1134346660" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAD: 1.36-fold Down; FDR = 0.000605; PValue = 9.52e-05; mean CPM = 48.46; BCL2-associated agonist of cell death" ID="ID_1631725619" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZYX: 1.29-fold Down; FDR = 0.00237; PValue = 0.00045; mean CPM = 287.5; Uncharacterized protein" ID="ID_1397976312" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK3: 3.55-fold Up; FDR = 0.00273; PValue = 0.000527; mean CPM = 1.136; p21 protein (Cdc42/Rac)-activated kinase 3" ID="ID_354587273" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHOA: 1.28-fold Down; FDR = 0.00295; PValue = 0.000575; mean CPM = 277.8; ras homolog gene family, member A" ID="ID_1036019514" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TXK: 3.95-fold Up; FDR = 0.00318; PValue = 0.000629; mean CPM = 1.067; TXK tyrosine kinase" ID="ID_300413933" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1B: 1.43-fold Up; FDR = 0.00346; PValue = 0.000693; mean CPM = 12.81; RAP1B, member of RAS oncogene family" ID="ID_930087701" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB4: 1.66-fold Down; FDR = 0.00369; PValue = 0.000748; mean CPM = 5.291; integrin, beta 4" ID="ID_1710554345" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIP5K1C: 1.27-fold Down; FDR = 0.00491; PValue = 0.00104; mean CPM = 37.75; phosphatidylinositol-4-phosphate 5-kinase, type I, gamma" ID="ID_51927133" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAV1: 1.33-fold Down; FDR = 0.00575; PValue = 0.00125; mean CPM = 228.7; caveolin-1" ID="ID_555058174" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VASP: 1.26-fold Down; FDR = 0.00581; PValue = 0.00126; mean CPM = 250.9; vasodilator-stimulated phosphoprotein" ID="ID_1537831356" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLN1: 1.26-fold Down; FDR = 0.0101; PValue = 0.00238; mean CPM = 1820; talin 1" ID="ID_869969050" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFB: 1.97-fold Down; FDR = 0.0133; PValue = 0.00326; mean CPM = 2.424; platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)" ID="ID_960112309" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FYN: 1.22-fold Up; FDR = 0.0156; PValue = 0.00393; mean CPM = 92.94; FYN oncogene related to SRC, FGR, YES" ID="ID_1331203002" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FARP2: 1.24-fold Down; FDR = 0.0162; PValue = 0.00411; mean CPM = 30.03; FERM, RhoGEF and pleckstrin domain protein 2" ID="ID_1358506805" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FN1: 1.7-fold Down; FDR = 0.0164; PValue = 0.00417; mean CPM = 40317; fibronectin 1" ID="ID_1313934371" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB2: 1.55-fold Down; FDR = 0.0187; PValue = 0.00485; mean CPM = 34.87; Integrin beta" ID="ID_1368113042" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA2B: 1.71-fold Down; FDR = 0.0187; PValue = 0.00486; mean CPM = 2.655; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)" ID="ID_77379797" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1576831382" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1065280012" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC2: 2.96-fold Up; FDR = 0.0309; PValue = 0.00872; mean CPM = 0.9737; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)" ID="ID_15058439" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KDR: 2.01-fold Up; FDR = 0.0328; PValue = 0.00936; mean CPM = 2.053; kinase insert domain receptor (a type III receptor tyrosine kinase)" ID="ID_159790618" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDPK1: 1.24-fold Down; FDR = 0.0361; PValue = 0.0105; mean CPM = 17.53; 3-phosphoinositide dependent protein kinase-1" ID="ID_1806129791" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL2A1: 2.38-fold Down; FDR = 0.0368; PValue = 0.0107; mean CPM = 1.117; Uncharacterized protein" ID="ID_225675489" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK6: 3.06-fold Down; FDR = 0.04; PValue = 0.0118; mean CPM = 0.9224; p21 protein (Cdc42/Rac)-activated kinase 6" ID="ID_1017951534" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK4: 1.21-fold Down; FDR = 0.0756; PValue = 0.0252; mean CPM = 16.78; p21 protein (Cdc42/Rac)-activated kinase 4" ID="ID_1012304415" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB1: 1.23-fold Up; FDR = 0.0759; PValue = 0.0253; mean CPM = 2700; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)" ID="ID_1417852184" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMA4: 1.2-fold Down; FDR = 0.0793; PValue = 0.0266; mean CPM = 624.4; laminin, alpha 4" ID="ID_1401482168" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1A: 1.17-fold Up; FDR = 0.0888; PValue = 0.0304; mean CPM = 37.16; RAP1A, member of RAS oncogene family" ID="ID_1606121644" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND1: 1.17-fold Up; FDR = 0.121; PValue = 0.0443; mean CPM = 867.3; cyclin D1" ID="ID_1892254168" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_1584117243" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IBSP: 2.51-fold Down; FDR = 0.128; PValue = 0.0476; mean CPM = 0.8896; integrin-binding sialoprotein" ID="ID_910453251" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK2: 1.15-fold Up; FDR = 0.134; PValue = 0.0502; mean CPM = 89.49; p21 protein (Cdc42/Rac)-activated kinase 2" ID="ID_1187267237" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_889633632" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1891773348" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTEN: 1.14-fold Up; FDR = 0.166; PValue = 0.065; mean CPM = 89.60; phosphatase and tensin homolog" ID="ID_1997617988" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ROCK2: 1.14-fold Up; FDR = 0.166; PValue = 0.065; mean CPM = 247.7; Rho-associated, coiled-coil containing protein kinase 2" ID="ID_189756168" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP1R12A: 1.14-fold Up; FDR = 0.167; PValue = 0.0655; mean CPM = 282.7; protein phosphatase 1, regulatory (inhibitor) subunit 12A" ID="ID_569790594" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VWF: 1.42-fold Down; FDR = 0.174; PValue = 0.069; mean CPM = 24.05; von Willebrand factor" ID="ID_391832521" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STYK1: 2-fold Up; FDR = 0.19; PValue = 0.0767; mean CPM = 1.085; serine/threonine/tyrosine kinase 1" ID="ID_622458677" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1555552139" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PARVB: 1.14-fold Down; FDR = 0.199; PValue = 0.0817; mean CPM = 34.65; parvin, beta" ID="ID_59824061" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_870657777" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BRAF: 1.14-fold Down; FDR = 0.228; PValue = 0.0964; mean CPM = 24.98; v-raf murine sarcoma viral oncogene homolog B1" ID="ID_1241245627" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ERBB2: 1.14-fold Down; FDR = 0.23; PValue = 0.0977; mean CPM = 119.0; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)" ID="ID_1586363803" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAV2: 1.14-fold Down; FDR = 0.24; PValue = 0.103; mean CPM = 25.69; caveolin 2" ID="ID_1046828186" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_977713797" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014969: 1.93-fold Down; FDR = 0.303; PValue = 0.137; mean CPM = 0.9384; Uncharacterized protein" ID="ID_1984605474" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB3: 1.6-fold Down; FDR = 0.303; PValue = 0.137; mean CPM = 1.445; laminin, beta 3" ID="ID_278831990" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_920659755" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND2: 1.2-fold Up; FDR = 0.335; PValue = 0.155; mean CPM = 76.91; cyclin D2" ID="ID_1590413574" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_395502856" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2: 1.48-fold Up; FDR = 0.384; PValue = 0.184; mean CPM = 1.344; Uncharacterized protein" ID="ID_651397181" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2: 1.1-fold Up; FDR = 0.394; PValue = 0.191; mean CPM = 102.5; PTK2 protein tyrosine kinase 2" ID="ID_16616039" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK6: 1.34-fold Up; FDR = 0.407; PValue = 0.198; mean CPM = 2.043; mitogen-activated protein kinase 6" ID="ID_376352082" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK12: 1.19-fold Down; FDR = 0.422; PValue = 0.208; mean CPM = 6.569; mitogen-activated protein kinase 12" ID="ID_700045794" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNN: 1.32-fold Up; FDR = 0.425; PValue = 0.209; mean CPM = 2.061; tenascin N" ID="ID_983726956" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THBS4: 1.64-fold Down; FDR = 0.498; PValue = 0.257; mean CPM = 0.9543; thrombospondin 4" ID="ID_822435135" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VEGFB: 1.1-fold Down; FDR = 0.512; PValue = 0.267; mean CPM = 16.03; vascular endothelial growth factor B" ID="ID_1724107719" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGR: 1.63-fold Up; FDR = 0.516; PValue = 0.269; mean CPM = 1.191; Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog" ID="ID_1416073585" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_364463510" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYLK2: 1.56-fold Down; FDR = 0.541; PValue = 0.288; mean CPM = 0.9259; myosin light chain kinase 2" ID="ID_853494291" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC3: 1.37-fold Down; FDR = 0.584; PValue = 0.318; mean CPM = 1.193; SHC-transforming protein 3; Uncharacterized protein" ID="ID_1792682429" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA9: 1.3-fold Down; FDR = 0.595; PValue = 0.326; mean CPM = 1.685; integrin, alpha 9" ID="ID_226102278" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDC42: 1.07-fold Down; FDR = 0.608; PValue = 0.335; mean CPM = 91.67; cell division cycle 42" ID="ID_1893182480" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL4A6: 1.4-fold Down; FDR = 0.631; PValue = 0.353; mean CPM = 1.078; collagen, type IV, alpha 6" ID="ID_1941845765" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VTN: 1.19-fold Up; FDR = 0.669; PValue = 0.382; mean CPM = 2.950; vitronectin" ID="ID_280515296" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014966: 1.43-fold Down; FDR = 0.72; PValue = 0.423; mean CPM = 0.9009; Uncharacterized protein" ID="ID_438815334" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA4: 1.16-fold Down; FDR = 0.722; PValue = 0.425; mean CPM = 5.425; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)" ID="ID_1945666086" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAM: 1.44-fold Down; FDR = 0.73; PValue = 0.432; mean CPM = 0.9052; integrin, alpha M (complement component 3 receptor 3 subunit)" ID="ID_1987452665" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB6: 1.4-fold Down; FDR = 0.732; PValue = 0.434; mean CPM = 0.9377; Integrin beta" ID="ID_1250869604" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAPGEF1: 1.05-fold Down; FDR = 0.763; PValue = 0.462; mean CPM = 70.38; Rap guanine nucleotide exchange factor (GEF) 1" ID="ID_1507705532" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRK: 1.05-fold Up; FDR = 0.791; PValue = 0.488; mean CPM = 59.92; v-crk sarcoma virus CT10 oncogene homolog (avian)" ID="ID_408769542" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HCK: 1.3-fold Down; FDR = 0.797; PValue = 0.494; mean CPM = 0.9272; Uncharacterized protein" ID="ID_818839982" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DOCK1: 1.05-fold Up; FDR = 0.825; PValue = 0.524; mean CPM = 165.2; dedicator of cytokinesis 1" ID="ID_1671655167" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FLT1: 1.08-fold Down; FDR = 0.849; PValue = 0.558; mean CPM = 28.21; fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)" ID="ID_1601407309" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAD: 1.66-fold Down; FDR = 0.85; PValue = 0.56; mean CPM = 0.8625; integrin, alpha D" ID="ID_299523591" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV1: 1.25-fold Down; FDR = 0.858; PValue = 0.572; mean CPM = 0.9515; vav 1 guanine nucleotide exchange factor" ID="ID_809669430" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_623135624" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK7: 1.04-fold Down; FDR = 0.899; PValue = 0.632; mean CPM = 16.93; Uncharacterized protein" ID="ID_221046709" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK1: 1.03-fold Down; FDR = 0.911; PValue = 0.705; mean CPM = 18.65; p21 protein (Cdc42/Rac)-activated kinase 1" ID="ID_1447116744" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_1196481030" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_894330441" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL11A2: 1.03-fold Down; FDR = 1; PValue = 0.872; mean CPM = 2.131; collagen, type XI, alpha 2" ID="ID_308643556" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFRB: 1.01-fold Up; FDR = 1; PValue = 0.883; mean CPM = 391.1; platelet-derived growth factor receptor, beta polypeptide" ID="ID_612719661" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGF: 1.06-fold Down; FDR = 1; PValue = 0.885; mean CPM = 0.8917; epidermal growth factor" ID="ID_231590300" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNXB: 1.03-fold Up; FDR = 1; PValue = 0.909; mean CPM = 1.078; tenascin XB" ID="ID_1826417491" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R4: 1.01-fold Down; FDR = 1; PValue = 0.913; mean CPM = 41.33; phosphoinositide-3-kinase, regulatory subunit 4" ID="ID_595864994" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK7: 1.01-fold Up; FDR = 1; PValue = 0.923; mean CPM = 0.8495; p21 protein (Cdc42/Rac)-activated kinase 7" ID="ID_408223418" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK4: 1.19-fold Down; FDR = 1; PValue = 0.95; mean CPM = 0.8611; mitogen-activated protein kinase 4" ID="ID_1576379933" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAL: 1.03-fold Up; FDR = 1; PValue = 0.95; mean CPM = 1.035; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)" ID="ID_10532704" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB7: 1.01-fold Down; FDR = 1; PValue = 0.968; mean CPM = 2.025; integrin, beta 7" ID="ID_765809078" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SRMS: 1.01-fold Down; FDR = 1; PValue = 0.978; mean CPM = 0.8505; src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites" ID="ID_466146748" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAV3: 1.02-fold Down; FDR = 1; PValue = 0.98; mean CPM = 0.7970; caveolin 3" ID="ID_1742949341" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNR: 1.08-fold Down; FDR = 1; PValue = 0.984; mean CPM = 0.8556; tenascin R (restrictin, janusin)" ID="ID_982516136" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FIGF: 1.07-fold Up; FDR = 1; PValue = 0.995; mean CPM = 0.8037; c-fos induced growth factor (vascular endothelial growth factor D)" ID="ID_117231920" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK6: 1.04-fold Up; FDR = 1; PValue = 1; mean CPM = 0.8141; PTK6 protein tyrosine kinase 6" ID="ID_1471704175" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Mitochondrial LC-Fatty Acid Beta-Oxidation (WP368:Rev45141): FDR = 1.85e-14, PValue = 1.83e-15" ID="ID_197747870" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="ACSL1: 6.98-fold Up; FDR = 1.75e-21; PValue = 4.92e-24; mean CPM = 194.6; acyl-CoA synthetase long-chain family member 1" ID="ID_592313576" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACSL4: 1.44-fold Up; FDR = 2.98e-05; PValue = 3.15e-06; mean CPM = 126.3; acyl-CoA synthetase long-chain family member 4" ID="ID_503683080" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SCP2: 1.34-fold Up; FDR = 0.000258; PValue = 3.65e-05; mean CPM = 107.5; sterol carrier protein 2" ID="ID_869602066" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACADL: 1.59-fold Up; FDR = 0.0017; PValue = 0.00031; mean CPM = 6.176; acyl-CoA dehydrogenase, long chain" ID="ID_223081990" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CPT2: 1.33-fold Down; FDR = 0.00216; PValue = 0.000405; mean CPM = 22.86; carnitine palmitoyltransferase 2" ID="ID_879960618" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PECR: 1.44-fold Up; FDR = 0.00406; PValue = 0.000836; mean CPM = 12.33; peroxisomal trans-2-enoyl-CoA reductase" ID="ID_889764389" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CPT1A: 1.38-fold Down; FDR = 0.00434; PValue = 0.000903; mean CPM = 110.4; carnitine palmitoyltransferase 1A (liver)" ID="ID_1016302387" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EHHADH: 1.35-fold Up; FDR = 0.0132; PValue = 0.00323; mean CPM = 11.95; enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase" ID="ID_957988587" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ECI1: 1.27-fold Down; FDR = 0.021; PValue = 0.00556; mean CPM = 16.80; enoyl-CoA delta isomerase 1" ID="ID_498815657" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HADH: 1.1-fold Up; FDR = 0.419; PValue = 0.205; mean CPM = 32.14; hydroxyacyl-CoA dehydrogenase" ID="ID_202693388" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HADHA: 1.06-fold Down; FDR = 0.721; PValue = 0.424; mean CPM = 170.9; hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit" ID="ID_1516513763" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC25A20: 1.06-fold Up; FDR = 0.778; PValue = 0.475; mean CPM = 18.03; solute carrier family 25 (carnitine/acylcarnitine translocase), member 20" ID="ID_1757542911" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACSL3: 1.05-fold Up; FDR = 0.787; PValue = 0.484; mean CPM = 61.21; acyl-CoA synthetase long-chain family member 3" ID="ID_890625523" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACADS: 1.01-fold Up; FDR = 1; PValue = 0.928; mean CPM = 17.72; acyl-CoA dehydrogenase, C-2 to C-3 short chain" ID="ID_1490598303" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Prolactin Signaling Pathway (WP2037:Rev45275): FDR = 9.48e-14, PValue = 9.87e-15" ID="ID_1698811048" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="IRF1: 18.6-fold Up; FDR = 1.53e-21; PValue = 4.24e-24; mean CPM = 240.7; interferon regulatory factor 1" ID="ID_843264655" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_1844640962" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1459509581" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5A: 2.28-fold Up; FDR = 6.87e-14; PValue = 8.58e-16; mean CPM = 21.55; signal transducer and activator of transcription 5A" ID="ID_1439671953" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_1930069455" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIAS3: 1.63-fold Down; FDR = 2.24e-10; PValue = 6.51e-12; mean CPM = 53.00; protein inhibitor of activated STAT, 3" ID="ID_1792473908" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_548237681" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRS1: 2.78-fold Up; FDR = 7.67e-09; PValue = 3.19e-10; mean CPM = 26.55; Uncharacterized protein" ID="ID_892719595" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FLNA: 2.35-fold Down; FDR = 2.01e-08; PValue = 9.45e-10; mean CPM = 7159; filamin A, alpha" ID="ID_913073135" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1366124012" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_1184409206" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_993469050" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_960966349" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_426936287" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_1386452187" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPIB: 1.45-fold Down; FDR = 8.64e-06; PValue = 8.03e-07; mean CPM = 806.4; peptidylprolyl isomerase B (cyclophilin B)" ID="ID_88854986" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1956297404" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTSD: 1.65-fold Down; FDR = 0.000162; PValue = 2.13e-05; mean CPM = 578.9; cathepsin D" ID="ID_1700219478" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS3: 1.69-fold Up; FDR = 0.000994; PValue = 0.000167; mean CPM = 37.76; suppressor of cytokine signaling 3" ID="ID_1275636831" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CISH: 1.95-fold Up; FDR = 0.00116; PValue = 0.0002; mean CPM = 5.083; cytokine inducible SH2-containing protein" ID="ID_1732166842" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTOR: 1.3-fold Down; FDR = 0.00117; PValue = 0.000201; mean CPM = 107.5; mechanistic target of rapamycin (serine/threonine kinase)" ID="ID_603853813" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GAB2: 1.33-fold Down; FDR = 0.00208; PValue = 0.000387; mean CPM = 22.59; GRB2-associated binding protein 2" ID="ID_57274133" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1334137694" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FYN: 1.22-fold Up; FDR = 0.0156; PValue = 0.00393; mean CPM = 92.94; FYN oncogene related to SRC, FGR, YES" ID="ID_1761151989" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS2: 1.31-fold Down; FDR = 0.0188; PValue = 0.0049; mean CPM = 35.29; suppressor of cytokine signaling 2" ID="ID_1491632415" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1712925881" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_731375499" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_100647106" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1851630553" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN1: 1.2-fold Down; FDR = 0.0495; PValue = 0.0152; mean CPM = 35.05; protein tyrosine phosphatase, non-receptor type 1" ID="ID_629504979" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_1900217236" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_1425324077" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF4EBP1: 1.23-fold Up; FDR = 0.0729; PValue = 0.0241; mean CPM = 40.55; eukaryotic translation initiation factor 4E binding protein 1" ID="ID_801023397" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TEC: 1.65-fold Up; FDR = 0.0729; PValue = 0.0241; mean CPM = 3.190; tec protein tyrosine kinase" ID="ID_1872503550" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB1: 1.23-fold Up; FDR = 0.0759; PValue = 0.0253; mean CPM = 2700; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)" ID="ID_995892132" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_1097818137" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AGAP2: 1.55-fold Up; FDR = 0.106; PValue = 0.0377; mean CPM = 2.136; ArfGAP with GTPase domain, ankyrin repeat and PH domain 2" ID="ID_488111525" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_1334147869" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_250094430" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_25608776" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="YWHAG: 1.14-fold Down; FDR = 0.162; PValue = 0.0632; mean CPM = 175.7; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide" ID="ID_1409590173" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_987613915" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_1555113504" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ERBB2: 1.14-fold Down; FDR = 0.23; PValue = 0.0977; mean CPM = 119.0; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)" ID="ID_58997658" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_588235766" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1205909378" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2: 1.1-fold Up; FDR = 0.394; PValue = 0.191; mean CPM = 102.5; PTK2 protein tyrosine kinase 2" ID="ID_773926876" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1910327676" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1935045087" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_547662201" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6: 1.08-fold Up; FDR = 0.584; PValue = 0.318; mean CPM = 892.5; ribosomal protein S6" ID="ID_1044153325" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_959912334" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NEK3: 1.1-fold Up; FDR = 0.77; PValue = 0.468; mean CPM = 5.147; NIMA-related kinase 3" ID="ID_793624157" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="YWHAZ: 1.05-fold Down; FDR = 0.785; PValue = 0.482; mean CPM = 341.0; 14-3-3 protein zeta/delta; Uncharacterized protein" ID="ID_219148201" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CBL: 1.05-fold Down; FDR = 0.824; PValue = 0.524; mean CPM = 51.06; Cas-Br-M (murine) ecotropic retroviral transforming sequence" ID="ID_1369173550" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV1: 1.25-fold Down; FDR = 0.858; PValue = 0.572; mean CPM = 0.9515; vav 1 guanine nucleotide exchange factor" ID="ID_1555469477" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZAP70: 1.25-fold Down; FDR = 0.872; PValue = 0.59; mean CPM = 0.8996; zeta-chain (TCR) associated protein kinase 70kDa" ID="ID_666862266" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_808335253" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB1: 1.04-fold Up; FDR = 0.88; PValue = 0.6; mean CPM = 30.80; Uncharacterized protein" ID="ID_1697343494" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="YWHAZ: 1.09-fold Up; FDR = 0.888; PValue = 0.61; mean CPM = 3.241; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide" ID="ID_966714031" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK1: 1.03-fold Down; FDR = 0.911; PValue = 0.705; mean CPM = 18.65; p21 protein (Cdc42/Rac)-activated kinase 1" ID="ID_38686054" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOS2: 1.4-fold Down; FDR = 0.917; PValue = 0.718; mean CPM = 0.8546; nitric oxide synthase 2, inducible" ID="ID_734174131" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_1281403311" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_744073161" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRLR: 1.06-fold Down; FDR = 1; PValue = 0.889; mean CPM = 1.017; prolactin receptor" ID="ID_1704934009" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_1622856801" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV2: No Change; FDR = 1; PValue = 0.976; mean CPM = 25.65; vav 2 guanine nucleotide exchange factor" ID="ID_323531613" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-5 signaling pathway (WP127:Rev45368): FDR = 1.1e-13, PValue = 1.2e-14" ID="ID_681526254" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_1486690168" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_974799224" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5A: 2.28-fold Up; FDR = 6.87e-14; PValue = 8.58e-16; mean CPM = 21.55; signal transducer and activator of transcription 5A" ID="ID_385937674" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_900203984" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_1056029714" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_598596164" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_1248871840" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_398294049" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPT: 2.89-fold Down; FDR = 3.14e-05; PValue = 3.34e-06; mean CPM = 2.105; microtubule-associated protein tau" ID="ID_85520714" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB2: 1.38-fold Down; FDR = 4.66e-05; PValue = 5.24e-06; mean CPM = 61.90; ribosomal protein S6 kinase, 70kDa, polypeptide 2" ID="ID_1879171693" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1153235527" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA1: 1.25-fold Down; FDR = 0.0241; PValue = 0.00652; mean CPM = 21.28; ribosomal protein S6 kinase, 90kDa, polypeptide 1" ID="ID_149667916" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_895943860" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_458276609" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KRAS: 1.35-fold Down; FDR = 0.0401; PValue = 0.0119; mean CPM = 13.10; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog" ID="ID_1865714755" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_1005398667" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_1752491036" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3A: 1.18-fold Down; FDR = 0.097; PValue = 0.0338; mean CPM = 25.14; Glycogen synthase kinase-3 alpha; Uncharacterized protein" ID="ID_1829843905" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_1456625976" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPRED1: 1.15-fold Up; FDR = 0.143; PValue = 0.0543; mean CPM = 41.74; sprouty-related, EVH1 domain containing 1" ID="ID_1646309089" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1935913779" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_212849285" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_923561974" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_1120847857" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2: 1.48-fold Up; FDR = 0.384; PValue = 0.184; mean CPM = 1.344; Uncharacterized protein" ID="ID_512472061" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1284611677" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_1540711641" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOXO3: 1.08-fold Down; FDR = 0.55; PValue = 0.294; mean CPM = 48.45; forkhead box O3" ID="ID_1014102928" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6: 1.08-fold Up; FDR = 0.584; PValue = 0.318; mean CPM = 892.5; ribosomal protein S6" ID="ID_1533882878" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_345282431" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB1: 1.04-fold Up; FDR = 0.88; PValue = 0.6; mean CPM = 30.80; Uncharacterized protein" ID="ID_1045109104" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_656091586" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL5RA: 1.1-fold Up; FDR = 0.958; PValue = 0.791; mean CPM = 0.8108; interleukin 5 receptor, alpha" ID="ID_1491790001" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BTK: No Change; FDR = 1; PValue = 0.965; mean CPM = 0.8336; Bruton agammaglobulinemia tyrosine kinase" ID="ID_372473312" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SYK: 1.11-fold Up; FDR = 1; PValue = 0.977; mean CPM = 0.8420; spleen tyrosine kinase" ID="ID_1111948717" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2: 1.03-fold Up; FDR = 1; PValue = 0.998; mean CPM = 0.7974; interleukin 2" ID="ID_317681257" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Oxidative Stress (WP408:Rev45296): FDR = 1.21e-13, PValue = 1.38e-14" ID="ID_599853137" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="MT1X: 11-fold Up; FDR = 1.03e-12; PValue = 1.68e-14; mean CPM = 108.2; Metallothionein" ID="ID_599283515" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOD1: 1.67-fold Up; FDR = 3.83e-10; PValue = 1.17e-11; mean CPM = 160.0; superoxide dismutase 1, soluble" ID="ID_18803399" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAT: 1.75-fold Up; FDR = 1.21e-09; PValue = 4.14e-11; mean CPM = 42.72; catalase" ID="ID_769469465" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFE2L2: 1.76-fold Up; FDR = 5.91e-09; PValue = 2.41e-10; mean CPM = 179.2; nuclear factor (erythroid-derived 2)-like 2" ID="ID_837516612" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOD2: 4.88-fold Up; FDR = 1.73e-08; PValue = 7.93e-10; mean CPM = 558.4; superoxide dismutase 2, mitochondrial" ID="ID_816452400" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HMOX1: 1.94-fold Up; FDR = 7.83e-05; PValue = 9.42e-06; mean CPM = 15.01; heme oxygenase (decycling) 1" ID="ID_1159893421" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYBA: 1.34-fold Up; FDR = 0.00107; PValue = 0.000183; mean CPM = 376.6; cytochrome b-245, alpha polypeptide" ID="ID_767406598" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOX4: 4.17-fold Down; FDR = 0.00443; PValue = 0.000922; mean CPM = 1.045; NADPH oxidase 4" ID="ID_623445028" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOD3: 1.7-fold Down; FDR = 0.00506; PValue = 0.00107; mean CPM = 36.72; superoxide dismutase 3, extracellular" ID="ID_215289738" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAOA: 1.43-fold Down; FDR = 0.00532; PValue = 0.00114; mean CPM = 367.7; monoamine oxidase A" ID="ID_1555959583" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_1909929068" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SP1: 1.23-fold Up; FDR = 0.0139; PValue = 0.00344; mean CPM = 75.49; Transcription factor Sp1 isoform a; Uncharacterized protein" ID="ID_1648909977" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MGST1: 1.29-fold Up; FDR = 0.0173; PValue = 0.00444; mean CPM = 84.66; microsomal glutathione S-transferase 1" ID="ID_1186076553" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSTT2B: 1.27-fold Up; FDR = 0.0194; PValue = 0.00509; mean CPM = 16.85; glutathione S-transferase theta 2B (gene/pseudogene)" ID="ID_1992051644" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TXN2: 1.21-fold Down; FDR = 0.026; PValue = 0.00713; mean CPM = 40.77; thioredoxin 2" ID="ID_924701118" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSR: 1.26-fold Up; FDR = 0.0263; PValue = 0.00721; mean CPM = 28.15; glutathione reductase" ID="ID_1643047958" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_311633745" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1251353545" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NQO1: 1.48-fold Up; FDR = 0.0421; PValue = 0.0125; mean CPM = 97.72; NAD(P)H dehydrogenase, quinone 1" ID="ID_67168773" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1244441584" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XDH: 1.62-fold Up; FDR = 0.495; PValue = 0.255; mean CPM = 0.9209; xanthine dehydrogenase" ID="ID_1064069679" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GCLC: 1.1-fold Up; FDR = 0.649; PValue = 0.367; mean CPM = 261.3; glutamate-cysteine ligase, catalytic subunit" ID="ID_1883828460" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYP1A1: 1.35-fold Up; FDR = 0.658; PValue = 0.373; mean CPM = 1.117; cytochrome P450, family 1, subfamily A, polypeptide 1" ID="ID_1414595256" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Fatty Acid Beta Oxidation (WP143:Rev45258): FDR = 1.42e-13, PValue = 1.7e-14" ID="ID_1801016768" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="ACSL1: 6.98-fold Up; FDR = 1.75e-21; PValue = 4.92e-24; mean CPM = 194.6; acyl-CoA synthetase long-chain family member 1" ID="ID_852125477" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACSL5: 8.65-fold Up; FDR = 4.07e-18; PValue = 2.39e-20; mean CPM = 34.19; acyl-CoA synthetase long-chain family member 5" ID="ID_1849465666" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GPD2: 2.11-fold Up; FDR = 1.4e-14; PValue = 1.58e-16; mean CPM = 142.3; glycerol-3-phosphate dehydrogenase 2 (mitochondrial)" ID="ID_521377479" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DECR1: 1.83-fold Up; FDR = 2.91e-10; PValue = 8.64e-12; mean CPM = 54.00; 2,4-dienoyl-CoA reductase, mitochondrial; Uncharacterized protein" ID="ID_387378409" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HADHB: 1.43-fold Up; FDR = 4.95e-06; PValue = 4.25e-07; mean CPM = 117.7; hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit" ID="ID_1050588212" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACSL4: 1.44-fold Up; FDR = 2.98e-05; PValue = 3.15e-06; mean CPM = 126.3; acyl-CoA synthetase long-chain family member 4" ID="ID_1104787499" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACADL: 1.59-fold Up; FDR = 0.0017; PValue = 0.00031; mean CPM = 6.176; acyl-CoA dehydrogenase, long chain" ID="ID_1863801095" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CPT2: 1.33-fold Down; FDR = 0.00216; PValue = 0.000405; mean CPM = 22.86; carnitine palmitoyltransferase 2" ID="ID_1955547212" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACAT1: 1.35-fold Down; FDR = 0.00247; PValue = 0.000471; mean CPM = 32.72; acetyl-CoA acetyltransferase 1" ID="ID_16186291" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CPT1A: 1.38-fold Down; FDR = 0.00434; PValue = 0.000903; mean CPM = 110.4; carnitine palmitoyltransferase 1A (liver)" ID="ID_274828864" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GCDH: 1.32-fold Down; FDR = 0.00538; PValue = 0.00115; mean CPM = 17.15; glutaryl-CoA dehydrogenase" ID="ID_1085454447" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ECI1: 1.27-fold Down; FDR = 0.021; PValue = 0.00556; mean CPM = 16.80; enoyl-CoA delta isomerase 1" ID="ID_399449410" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACSL6: 2.32-fold Down; FDR = 0.0551; PValue = 0.0173; mean CPM = 1.472; acyl-CoA synthetase long-chain family member 6" ID="ID_698489931" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LIPE: 1.27-fold Down; FDR = 0.0669; PValue = 0.0217; mean CPM = 9.982; lipase, hormone-sensitive" ID="ID_1326622931" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DLD: 1.16-fold Up; FDR = 0.12; PValue = 0.0435; mean CPM = 57.77; dihydrolipoamide dehydrogenase" ID="ID_1347244825" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HADH: 1.1-fold Up; FDR = 0.419; PValue = 0.205; mean CPM = 32.14; hydroxyacyl-CoA dehydrogenase" ID="ID_67076584" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LIPC: 1.39-fold Up; FDR = 0.676; PValue = 0.388; mean CPM = 0.9915; lipase, hepatic" ID="ID_100857680" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TPI1: 1.07-fold Down; FDR = 0.681; PValue = 0.391; mean CPM = 521.3; triosephosphate isomerase 1" ID="ID_1942576897" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HADHA: 1.06-fold Down; FDR = 0.721; PValue = 0.424; mean CPM = 170.9; hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit" ID="ID_1222025297" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000004177: 1.07-fold Up; FDR = 0.768; PValue = 0.466; mean CPM = 15.82; Uncharacterized protein" ID="ID_817800470" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACSS2: 1.05-fold Down; FDR = 0.773; PValue = 0.471; mean CPM = 38.17; Uncharacterized protein" ID="ID_622411966" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC25A20: 1.06-fold Up; FDR = 0.778; PValue = 0.475; mean CPM = 18.03; solute carrier family 25 (carnitine/acylcarnitine translocase), member 20" ID="ID_509125724" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACSL3: 1.05-fold Up; FDR = 0.787; PValue = 0.484; mean CPM = 61.21; acyl-CoA synthetase long-chain family member 3" ID="ID_1412115161" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRAT: 1.04-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 64.03; carnitine O-acetyltransferase" ID="ID_1885908937" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PNPLA2: 1.03-fold Down; FDR = 0.903; PValue = 0.643; mean CPM = 52.84; patatin-like phospholipase domain containing 2" ID="ID_47385957" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CPT1B: 1.05-fold Up; FDR = 0.923; PValue = 0.728; mean CPM = 5.764; carnitine palmitoyltransferase 1B (muscle)" ID="ID_134251411" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TPI1: 1.02-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 133.1; triosephosphate isomerase 1" ID="ID_822182809" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LPL: 1.08-fold Down; FDR = 1; PValue = 0.868; mean CPM = 0.9050; lipoprotein lipase" ID="ID_1239106313" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ECHS1: 1.01-fold Up; FDR = 1; PValue = 0.885; mean CPM = 49.79; enoyl CoA hydratase, short chain, 1, mitochondrial" ID="ID_787761290" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACADS: 1.01-fold Up; FDR = 1; PValue = 0.928; mean CPM = 17.72; acyl-CoA dehydrogenase, C-2 to C-3 short chain" ID="ID_143532250" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GK2: 1.12-fold Down; FDR = 1; PValue = 0.972; mean CPM = 0.8255; glycerol kinase 2" ID="ID_1587980534" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LIPF: 1.02-fold Down; FDR = 1; PValue = 0.985; mean CPM = 0.8334; lipase, gastric" ID="ID_573969930" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Osteoblast Signaling (WP322:Rev45323): FDR = 1.43e-13, PValue = 1.79e-14" ID="ID_412089430" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="PDGFRA: 2.76-fold Up; FDR = 3.93e-14; PValue = 4.67e-16; mean CPM = 492.9; platelet-derived growth factor receptor, alpha polypeptide" ID="ID_1383296881" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL1A1: 21.5-fold Down; FDR = 1.13e-13; PValue = 1.5e-15; mean CPM = 15389; collagen, type I, alpha 1" ID="ID_509352276" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAV: 2.64-fold Down; FDR = 6.04e-11; PValue = 1.51e-12; mean CPM = 337.3; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)" ID="ID_724412885" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB3: 5.02-fold Down; FDR = 1.72e-09; PValue = 6.17e-11; mean CPM = 43.21; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)" ID="ID_1184331383" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C17orf57: 5.51-fold Down; FDR = 0.000238; PValue = 3.33e-05; mean CPM = 1.571; EF-hand domain-containing protein C17orf57" ID="ID_1171849192" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFB: 1.97-fold Down; FDR = 0.0133; PValue = 0.00326; mean CPM = 2.424; platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)" ID="ID_305670512" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF11: 1.8-fold Up; FDR = 0.039; PValue = 0.0115; mean CPM = 2.535; tumor necrosis factor (ligand) superfamily, member 11" ID="ID_675602202" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTH1R: 2-fold Down; FDR = 0.0838; PValue = 0.0284; mean CPM = 1.299; parathyroid hormone 1 receptor" ID="ID_915692138" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF11B: 1.31-fold Down; FDR = 0.121; PValue = 0.0439; mean CPM = 722.1; Uncharacterized protein" ID="ID_285265279" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IBSP: 2.51-fold Down; FDR = 0.128; PValue = 0.0476; mean CPM = 0.8896; integrin-binding sialoprotein" ID="ID_954125871" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF23: 2.01-fold Down; FDR = 0.188; PValue = 0.0759; mean CPM = 0.9718; fibroblast growth factor 23" ID="ID_1825677058" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFRB: 1.01-fold Up; FDR = 1; PValue = 0.883; mean CPM = 391.1; platelet-derived growth factor receptor, beta polypeptide" ID="ID_1113047561" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTH: No Change; FDR = 1; PValue = 1; mean CPM = 0.7843; parathyroid hormone" ID="ID_120720115" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Kit receptor signaling pathway (WP304:Rev44883): FDR = 1.47e-13, PValue = 1.91e-14" ID="ID_434249212" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_1326906549" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1193181675" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5A: 2.28-fold Up; FDR = 6.87e-14; PValue = 8.58e-16; mean CPM = 21.55; signal transducer and activator of transcription 5A" ID="ID_1005786507" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_1325247777" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_1342397844" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_685782802" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_367713375" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_1714383165" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_361344746" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPT: 2.89-fold Down; FDR = 3.14e-05; PValue = 3.34e-06; mean CPM = 2.105; microtubule-associated protein tau" ID="ID_974865128" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAD: 1.36-fold Down; FDR = 0.000605; PValue = 9.52e-05; mean CPM = 48.46; BCL2-associated agonist of cell death" ID="ID_678688915" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG1: 1.31-fold Down; FDR = 0.00352; PValue = 0.000707; mean CPM = 53.66; phospholipase C, gamma 1" ID="ID_315471423" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1639833600" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA1: 1.25-fold Down; FDR = 0.0241; PValue = 0.00652; mean CPM = 21.28; ribosomal protein S6 kinase, 90kDa, polypeptide 1" ID="ID_767231856" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_613921102" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INPP5D: 1.88-fold Down; FDR = 0.0276; PValue = 0.00763; mean CPM = 5.690; inositol polyphosphate-5-phosphatase, 145kDa" ID="ID_111365290" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_58547954" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_1312209966" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TEC: 1.65-fold Up; FDR = 0.0729; PValue = 0.0241; mean CPM = 3.190; tec protein tyrosine kinase" ID="ID_21764961" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB7: 1.46-fold Down; FDR = 0.12; PValue = 0.0435; mean CPM = 2.867; Uncharacterized protein" ID="ID_1373393767" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SNAI2: 1.27-fold Up; FDR = 0.127; PValue = 0.0468; mean CPM = 55.60; snail homolog 2 (Drosophila)" ID="ID_624031878" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KITLG: 1.31-fold Up; FDR = 0.209; PValue = 0.0867; mean CPM = 5.766; KIT ligand" ID="ID_6331252" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_1867565425" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS6: 1.13-fold Up; FDR = 0.248; PValue = 0.107; mean CPM = 30.93; suppressor of cytokine signaling 6" ID="ID_1702342782" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBX2: 1.17-fold Up; FDR = 0.308; PValue = 0.14; mean CPM = 43.84; T-box 2" ID="ID_1039892012" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EP300: 1.11-fold Up; FDR = 0.312; PValue = 0.142; mean CPM = 162.8; E1A binding protein p300" ID="ID_282918833" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2: 1.48-fold Up; FDR = 0.384; PValue = 0.184; mean CPM = 1.344; Uncharacterized protein" ID="ID_1365665002" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DOK1: 1.12-fold Down; FDR = 0.406; PValue = 0.198; mean CPM = 92.16; docking protein 1, 62kDa (downstream of tyrosine kinase 1)" ID="ID_282734771" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_467388921" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_918641164" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_35584422" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOXO3: 1.08-fold Down; FDR = 0.55; PValue = 0.294; mean CPM = 48.45; forkhead box O3" ID="ID_529438118" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6: 1.08-fold Up; FDR = 0.584; PValue = 0.318; mean CPM = 892.5; ribosomal protein S6" ID="ID_341376108" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCB: 1.86-fold Up; FDR = 0.727; PValue = 0.43; mean CPM = 0.8705; protein kinase C, beta" ID="ID_1717635378" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRK: 1.05-fold Up; FDR = 0.791; PValue = 0.488; mean CPM = 59.92; v-crk sarcoma virus CT10 oncogene homolog (avian)" ID="ID_1845071838" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB10: 1.06-fold Up; FDR = 0.808; PValue = 0.505; mean CPM = 72.84; growth factor receptor-bound protein 10" ID="ID_1346971081" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CBL: 1.05-fold Down; FDR = 0.824; PValue = 0.524; mean CPM = 51.06; Cas-Br-M (murine) ecotropic retroviral transforming sequence" ID="ID_1792304607" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV1: 1.25-fold Down; FDR = 0.858; PValue = 0.572; mean CPM = 0.9515; vav 1 guanine nucleotide exchange factor" ID="ID_186854106" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_619077608" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB1: 1.04-fold Up; FDR = 0.88; PValue = 0.6; mean CPM = 30.80; Uncharacterized protein" ID="ID_59376124" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_1630518260" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA3: 1.02-fold Up; FDR = 0.982; PValue = 0.829; mean CPM = 58.16; ribosomal protein S6 kinase, 90kDa, polypeptide 3" ID="ID_647708705" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MATK: 1.32-fold Down; FDR = 0.985; PValue = 0.834; mean CPM = 0.8687; megakaryocyte-associated tyrosine kinase" ID="ID_1587608263" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BTK: No Change; FDR = 1; PValue = 0.965; mean CPM = 0.8336; Bruton agammaglobulinemia tyrosine kinase" ID="ID_1849228544" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Cholesterol Biosynthesis (WP197:Rev44991): FDR = 2.6e-13, PValue = 3.52e-14" ID="ID_907432301" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="DHCR7: 3.58-fold Down; FDR = 6.01e-13; PValue = 9.35e-15; mean CPM = 15.72; 7-dehydrocholesterol reductase" ID="ID_969789157" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MVD: 2.35-fold Down; FDR = 8.85e-13; PValue = 1.42e-14; mean CPM = 18.63; mevalonate (diphospho) decarboxylase" ID="ID_654786355" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SREBF2: 2.26-fold Down; FDR = 4.11e-12; PValue = 7.71e-14; mean CPM = 92.78; sterol regulatory element binding transcription factor 2" ID="ID_1969865580" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SQLE: 2.41-fold Down; FDR = 1.15e-07; PValue = 6.53e-09; mean CPM = 13.58; squalene epoxidase" ID="ID_992695201" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MVK: 1.96-fold Down; FDR = 9.13e-07; PValue = 6.52e-08; mean CPM = 6.973; mevalonate kinase" ID="ID_1929312955" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SC4MOL: 1.54-fold Down; FDR = 1.24e-05; PValue = 1.18e-06; mean CPM = 17.46; sterol-C4-methyl oxidase-like" ID="ID_1978886934" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LSS: 1.52-fold Down; FDR = 1.4e-05; PValue = 1.36e-06; mean CPM = 23.62; lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)" ID="ID_318588510" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PMVK: 1.42-fold Down; FDR = 0.000723; PValue = 0.000117; mean CPM = 36.39; phosphomevalonate kinase" ID="ID_1666951822" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HMGCS1: 1.31-fold Down; FDR = 0.00578; PValue = 0.00125; mean CPM = 19.39; 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)" ID="ID_162380824" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HMGCR: 1.25-fold Down; FDR = 0.00707; PValue = 0.00157; mean CPM = 46.64; 3-hydroxy-3-methylglutaryl-CoA reductase" ID="ID_225880751" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYP51A1: 1.2-fold Down; FDR = 0.0512; PValue = 0.0158; mean CPM = 34.30; cytochrome P450, family 51, subfamily A, polypeptide 1" ID="ID_1133660049" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FDPS: 1.15-fold Down; FDR = 0.126; PValue = 0.0464; mean CPM = 49.16; farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)" ID="ID_762341398" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SC5DL: 1.17-fold Up; FDR = 0.197; PValue = 0.0805; mean CPM = 23.20; sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like" ID="ID_942219158" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SREBF1: 1.11-fold Down; FDR = 0.324; PValue = 0.149; mean CPM = 179.9; sterol regulatory element binding transcription factor 1" ID="ID_1618338573" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FDFT1: 1.12-fold Up; FDR = 0.359; PValue = 0.169; mean CPM = 22.76; farnesyl-diphosphate farnesyltransferase 1" ID="ID_1773571728" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NSDHL: 1.11-fold Down; FDR = 0.362; PValue = 0.171; mean CPM = 34.39; NAD(P) dependent steroid dehydrogenase-like" ID="ID_1747586646" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IDI1: 1.1-fold Down; FDR = 0.525; PValue = 0.276; mean CPM = 20.34; isopentenyl-diphosphate delta isomerase 1" ID="ID_641783251" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-4 signaling pathway (WP395:Rev45367): FDR = 3.86e-13, PValue = 5.42e-14" ID="ID_355321472" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_153572867" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1593548350" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_1787576838" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_1109910339" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRS1: 2.78-fold Up; FDR = 7.67e-09; PValue = 3.19e-10; mean CPM = 26.55; Uncharacterized protein" ID="ID_1181891184" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_941718384" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_136939812" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1894654734" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS5: 1.38-fold Up; FDR = 4.45e-05; PValue = 4.96e-06; mean CPM = 88.27; suppressor of cytokine signaling 5" ID="ID_144160609" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF2: 1.34-fold Up; FDR = 0.000403; PValue = 6.01e-05; mean CPM = 39.83; activating transcription factor 2" ID="ID_301757215" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAD: 1.36-fold Down; FDR = 0.000605; PValue = 9.52e-05; mean CPM = 48.46; BCL2-associated agonist of cell death" ID="ID_184978459" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GATA3: 2.81-fold Up; FDR = 0.000734; PValue = 0.000119; mean CPM = 2.229; GATA binding protein 3" ID="ID_862286280" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS3: 1.69-fold Up; FDR = 0.000994; PValue = 0.000167; mean CPM = 37.76; suppressor of cytokine signaling 3" ID="ID_176164147" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFIL3: 1.37-fold Up; FDR = 0.00114; PValue = 0.000196; mean CPM = 50.42; nuclear factor, interleukin 3 regulated" ID="ID_1972177832" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK3: 2.31-fold Up; FDR = 0.00186; PValue = 0.000342; mean CPM = 2.154; Janus kinase 3" ID="ID_390520154" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GAB2: 1.33-fold Down; FDR = 0.00208; PValue = 0.000387; mean CPM = 22.59; GRB2-associated binding protein 2" ID="ID_1237088638" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_502126283" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FES: 1.34-fold Up; FDR = 0.00677; PValue = 0.0015; mean CPM = 22.71; feline sarcoma oncogene" ID="ID_1775693781" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYK2: 1.24-fold Down; FDR = 0.0142; PValue = 0.00354; mean CPM = 42.58; tyrosine kinase 2" ID="ID_1511104671" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_226708508" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DOK2: 1.76-fold Down; FDR = 0.0214; PValue = 0.00569; mean CPM = 2.236; docking protein 2, 56kDa" ID="ID_1277903034" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1269124370" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INPP5D: 1.88-fold Down; FDR = 0.0276; PValue = 0.00763; mean CPM = 5.690; inositol polyphosphate-5-phosphatase, 145kDa" ID="ID_231058295" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_754189016" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_24262065" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT6: 1.18-fold Up; FDR = 0.0727; PValue = 0.024; mean CPM = 217.5; signal transducer and activator of transcription 6, interleukin-4 induced" ID="ID_589586671" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_48060923" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_1192834485" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC5: 1.51-fold Down; FDR = 0.134; PValue = 0.0501; mean CPM = 18.55; Baculoviral IAP repeat-containing protein 5 isoform 1; Uncharacterized protein" ID="ID_1286627444" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_930491595" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_879803864" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EP300: 1.11-fold Up; FDR = 0.312; PValue = 0.142; mean CPM = 162.8; E1A binding protein p300" ID="ID_632152806" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_562263170" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_228532498" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_139349176" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_1416351094" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRH1: 1.25-fold Up; FDR = 0.455; PValue = 0.228; mean CPM = 4.779; histamine receptor H1" ID="ID_1600324171" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL4R: 1.05-fold Down; FDR = 0.803; PValue = 0.499; mean CPM = 193.5; interleukin 4 receptor" ID="ID_1408887822" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CBL: 1.05-fold Down; FDR = 0.824; PValue = 0.524; mean CPM = 51.06; Cas-Br-M (murine) ecotropic retroviral transforming sequence" ID="ID_1345096287" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1400445518" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB1: 1.04-fold Up; FDR = 0.88; PValue = 0.6; mean CPM = 30.80; Uncharacterized protein" ID="ID_1448808333" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL4: 1.27-fold Down; FDR = 0.933; PValue = 0.745; mean CPM = 0.8077; interleukin 4" ID="ID_1334770060" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="p38 MAPK Signaling Pathway (WP400:Rev45281): FDR = 4.06e-13, PValue = 5.92e-14" ID="ID_833669531" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_42577602" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_1144758647" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MEF2D: 1.73-fold Down; FDR = 2.02e-08; PValue = 9.5e-10; mean CPM = 61.43; myocyte enhancer factor 2D" ID="ID_380283700" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DDIT3: 2.05-fold Up; FDR = 1.46e-06; PValue = 1.09e-07; mean CPM = 45.52; DNA-damage-inducible transcript 3" ID="ID_818020842" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA5: 3.28-fold Up; FDR = 1.4e-05; PValue = 1.36e-06; mean CPM = 2.288; ribosomal protein S6 kinase, 90kDa, polypeptide 5" ID="ID_583087973" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF2: 1.34-fold Up; FDR = 0.000403; PValue = 6.01e-05; mean CPM = 39.83; activating transcription factor 2" ID="ID_674965409" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_805510616" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAX: 1.28-fold Up; FDR = 0.00569; PValue = 0.00123; mean CPM = 29.78; MYC associated factor X" ID="ID_1097226625" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB1: 1.21-fold Up; FDR = 0.0313; PValue = 0.00884; mean CPM = 36.07; cAMP responsive element binding protein 1" ID="ID_1513888223" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRADD: 1.22-fold Up; FDR = 0.0319; PValue = 0.00907; mean CPM = 34.75; TNFRSF1A-associated via death domain" ID="ID_1410643987" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFBR1: 1.2-fold Up; FDR = 0.037; PValue = 0.0108; mean CPM = 90.92; transforming growth factor, beta receptor 1" ID="ID_1157288327" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_1709356270" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_782873119" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MKNK1: 1.27-fold Down; FDR = 0.0706; PValue = 0.0232; mean CPM = 9.169; MAP kinase interacting serine/threonine kinase 1" ID="ID_1486772766" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K9: 1.62-fold Down; FDR = 0.177; PValue = 0.0705; mean CPM = 1.806; mitogen-activated protein kinase kinase kinase 9" ID="ID_1169930832" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1466108259" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_627608186" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPKAPK5: 1.15-fold Down; FDR = 0.297; PValue = 0.134; mean CPM = 13.06; mitogen-activated protein kinase-activated protein kinase 5" ID="ID_1699901413" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1196413153" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K5: 1.21-fold Down; FDR = 0.6; PValue = 0.33; mean CPM = 8.023; mitogen-activated protein kinase kinase kinase 5" ID="ID_1922498231" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDC42: 1.07-fold Down; FDR = 0.608; PValue = 0.335; mean CPM = 91.67; cell division cycle 42" ID="ID_1325967013" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPKAPK2: 1.06-fold Down; FDR = 0.733; PValue = 0.435; mean CPM = 82.16; mitogen-activated protein kinase-activated protein kinase 2" ID="ID_290615813" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLA2G4A: 1.08-fold Down; FDR = 0.836; PValue = 0.541; mean CPM = 40.53; phospholipase A2, group IVA (cytosolic, calcium-dependent)" ID="ID_1653496404" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASGRF1: 1.14-fold Down; FDR = 0.903; PValue = 0.648; mean CPM = 1.594; Ras protein-specific guanine nucleotide-releasing factor 1" ID="ID_1558250800" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB2: 1.05-fold Down; FDR = 0.903; PValue = 0.655; mean CPM = 110.8; transforming growth factor, beta 2" ID="ID_1123492612" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_1611195831" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_624996882" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_1433641859" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DAXX: No Change; FDR = 1; PValue = 0.984; mean CPM = 106.5; Death domain-associated protein 6 (Daxx)(hDaxx)(Fas death domain-associated protein)(ETS1-associated protein 1)(EAP1)" ID="ID_83319217" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="AMPK signaling (WP1403:Rev44950): FDR = 8.03e-13, PValue = 1.21e-13" ID="ID_651553441" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="EEF2: 1.9-fold Down; FDR = 4.62e-10; PValue = 1.45e-11; mean CPM = 2932; eukaryotic translation elongation factor 2" ID="ID_889490342" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FASN: 2.14-fold Down; FDR = 1.36e-09; PValue = 4.74e-11; mean CPM = 192.4; fatty acid synthase" ID="ID_543304002" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INSR: 1.93-fold Down; FDR = 1.24e-08; PValue = 5.48e-10; mean CPM = 118.3; insulin receptor" ID="ID_21108124" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EEF2K: 1.75-fold Down; FDR = 2.51e-08; PValue = 1.21e-09; mean CPM = 31.50; eukaryotic elongation factor-2 kinase" ID="ID_228625497" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_81215405" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCB1: 1.71-fold Up; FDR = 1.31e-06; PValue = 9.73e-08; mean CPM = 34.36; phospholipase C, beta 1 (phosphoinositide-specific)" ID="ID_1160371682" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1986631116" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_1018261879" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKAA2: 1.7-fold Down; FDR = 5.6e-06; PValue = 4.89e-07; mean CPM = 11.23; protein kinase, AMP-activated, alpha 2 catalytic subunit" ID="ID_1283175914" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TSC2: 1.44-fold Down; FDR = 1e-05; PValue = 9.42e-07; mean CPM = 124.0; tuberous sclerosis 2" ID="ID_1509611112" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKAG2: 1.62-fold Down; FDR = 1.04e-05; PValue = 9.84e-07; mean CPM = 16.27; protein kinase, AMP-activated, gamma 2 non-catalytic subunit" ID="ID_1477132996" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPTOR: 1.4-fold Down; FDR = 2.58e-05; PValue = 2.69e-06; mean CPM = 53.57; regulatory associated protein of MTOR, complex 1" ID="ID_1034625621" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB2: 1.38-fold Down; FDR = 4.66e-05; PValue = 5.24e-06; mean CPM = 61.90; ribosomal protein S6 kinase, 70kDa, polypeptide 2" ID="ID_1630772854" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAMKK1: 2.03-fold Down; FDR = 6.16e-05; PValue = 7.19e-06; mean CPM = 9.699; calcium/calmodulin-dependent protein kinase kinase 1, alpha" ID="ID_1242577840" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKAA1: 1.32-fold Up; FDR = 0.000825; PValue = 0.000135; mean CPM = 40.69; protein kinase, AMP-activated, alpha 1 catalytic subunit" ID="ID_163846144" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STRADB: 1.42-fold Up; FDR = 0.000944; PValue = 0.000158; mean CPM = 14.01; STE20-related kinase adaptor beta" ID="ID_742244710" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTOR: 1.3-fold Down; FDR = 0.00117; PValue = 0.000201; mean CPM = 107.5; mechanistic target of rapamycin (serine/threonine kinase)" ID="ID_1759366164" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPARGC1B: 1.57-fold Down; FDR = 0.00147; PValue = 0.000262; mean CPM = 8.323; peroxisome proliferator-activated receptor gamma, coactivator 1 beta" ID="ID_1046113114" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACACA: 1.27-fold Down; FDR = 0.00395; PValue = 0.000809; mean CPM = 54.13; acetyl-CoA carboxylase alpha" ID="ID_216720286" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CPT1A: 1.38-fold Down; FDR = 0.00434; PValue = 0.000903; mean CPM = 110.4; carnitine palmitoyltransferase 1A (liver)" ID="ID_687320880" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAMKK2: 1.27-fold Down; FDR = 0.00456; PValue = 0.000955; mean CPM = 37.99; calcium/calmodulin-dependent protein kinase kinase 2, beta" ID="ID_647405987" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HMGCR: 1.25-fold Down; FDR = 0.00707; PValue = 0.00157; mean CPM = 46.64; 3-hydroxy-3-methylglutaryl-CoA reductase" ID="ID_557448529" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CPT1C: 1.29-fold Down; FDR = 0.0155; PValue = 0.00391; mean CPM = 20.57; carnitine palmitoyltransferase 1C" ID="ID_1701027354" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADIPOR2: 1.46-fold Down; FDR = 0.0179; PValue = 0.00461; mean CPM = 21.90; adiponectin receptor 2" ID="ID_1257386983" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1737794732" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LEP: 1.67-fold Down; FDR = 0.0401; PValue = 0.0118; mean CPM = 63.70; leptin" ID="ID_1588680697" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TSC1: 1.19-fold Down; FDR = 0.0564; PValue = 0.0177; mean CPM = 38.34; tuberous sclerosis 1" ID="ID_659187483" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LIPE: 1.27-fold Down; FDR = 0.0669; PValue = 0.0217; mean CPM = 9.982; lipase, hormone-sensitive" ID="ID_182656245" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF4EBP1: 1.23-fold Up; FDR = 0.0729; PValue = 0.0241; mean CPM = 40.55; eukaryotic translation initiation factor 4E binding protein 1" ID="ID_287276264" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNB1: 1.39-fold Down; FDR = 0.0958; PValue = 0.0333; mean CPM = 44.87; cyclin B1" ID="ID_83638862" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRTC2: 1.18-fold Up; FDR = 0.0976; PValue = 0.0341; mean CPM = 27.36; CREB regulated transcription coactivator 2" ID="ID_1945639435" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ELAVL1: 1.13-fold Down; FDR = 0.206; PValue = 0.085; mean CPM = 53.94; ELAV-like protein 1; Uncharacterized protein" ID="ID_1938708626" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1A: 1.16-fold Down; FDR = 0.28; PValue = 0.124; mean CPM = 363.2; Cyclin-dependent kinase inhibitor 1; Uncharacterized protein" ID="ID_1563710886" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC2A4RG: 1.14-fold Up; FDR = 0.296; PValue = 0.133; mean CPM = 17.77; SLC2A4 regulator" ID="ID_1718288372" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKAB1: 1.12-fold Up; FDR = 0.3; PValue = 0.136; mean CPM = 30.19; protein kinase, AMP-activated, beta 1 non-catalytic subunit" ID="ID_1260256723" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SREBF1: 1.11-fold Down; FDR = 0.324; PValue = 0.149; mean CPM = 179.9; sterol regulatory element binding transcription factor 1" ID="ID_1521532539" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_626310921" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP53: 1.11-fold Down; FDR = 0.364; PValue = 0.172; mean CPM = 33.25; tumor protein p53" ID="ID_348648092" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKAG1: 1.1-fold Up; FDR = 0.365; PValue = 0.173; mean CPM = 52.15; Uncharacterized protein" ID="ID_997185817" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAB39: 1.11-fold Up; FDR = 0.371; PValue = 0.176; mean CPM = 33.59; calcium binding protein 39" ID="ID_547537028" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1302714121" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GYS1: 1.1-fold Down; FDR = 0.405; PValue = 0.197; mean CPM = 143.6; glycogen synthase 1 (muscle)" ID="ID_1353369483" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNA2: 1.24-fold Down; FDR = 0.441; PValue = 0.22; mean CPM = 24.05; cyclin A2" ID="ID_877642607" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LEPR: 1.52-fold Down; FDR = 0.489; PValue = 0.251; mean CPM = 1.051; leptin receptor" ID="ID_1913047142" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AC002126.5: 1.1-fold Down; FDR = 0.495; PValue = 0.255; mean CPM = 18.66; UPF0402 protein" ID="ID_908619486" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADRA1B: 1.31-fold Down; FDR = 0.506; PValue = 0.262; mean CPM = 1.799; adrenergic, alpha-1B-, receptor" ID="ID_1902285083" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADIPOR1: 1.06-fold Up; FDR = 0.694; PValue = 0.402; mean CPM = 101.7; adiponectin receptor 1" ID="ID_275153008" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADIPOQ: 1.98-fold Down; FDR = 0.729; PValue = 0.431; mean CPM = 0.8241; adiponectin, C1Q and collagen domain containing" ID="ID_311713527" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACG: 1.51-fold Down; FDR = 0.795; PValue = 0.491; mean CPM = 0.8026; protein kinase, cAMP-dependent, catalytic, gamma" ID="ID_988323282" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKAB2: 1.07-fold Down; FDR = 0.809; PValue = 0.505; mean CPM = 10.04; protein kinase, AMP-activated, beta 2 non-catalytic subunit" ID="ID_1415807500" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB1: 1.04-fold Up; FDR = 0.88; PValue = 0.6; mean CPM = 30.80; Uncharacterized protein" ID="ID_396906709" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STRADA: 1.04-fold Down; FDR = 0.883; PValue = 0.604; mean CPM = 18.06; STE20-related kinase adaptor alpha" ID="ID_1790085628" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACB: 1.03-fold Up; FDR = 0.911; PValue = 0.694; mean CPM = 30.10; protein kinase, cAMP-dependent, catalytic, beta" ID="ID_168290862" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INS: 1.11-fold Up; FDR = 0.914; PValue = 0.712; mean CPM = 0.7930; insulin" ID="ID_1854500057" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CPT1B: 1.05-fold Up; FDR = 0.923; PValue = 0.728; mean CPM = 5.764; carnitine palmitoyltransferase 1B (muscle)" ID="ID_113632159" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNA1: 1.28-fold Down; FDR = 0.928; PValue = 0.736; mean CPM = 0.8658; cyclin A1" ID="ID_1777481485" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADRA1A: 1.25-fold Up; FDR = 0.942; PValue = 0.76; mean CPM = 0.8073; Macaca mulatta adrenergic, alpha-1A-, receptor (ADRA1A), mRNA." ID="ID_305911668" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STK11: 1.01-fold Up; FDR = 1; PValue = 0.918; mean CPM = 47.98; serine/threonine kinase 11" ID="ID_1966763629" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GYS2: 1.01-fold Down; FDR = 1; PValue = 0.983; mean CPM = 0.7991; glycogen synthase 2 (liver)" ID="ID_1885532125" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Matrix Metalloproteinases (WP129:Rev44892): FDR = 8.36e-13, PValue = 1.31e-13" ID="ID_1806774933" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="MMP14: 1.69-fold Down; FDR = 6e-09; PValue = 2.46e-10; mean CPM = 390.7; matrix metallopeptidase 14 (membrane-inserted)" ID="ID_938794550" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TIMP2: 1.66-fold Down; FDR = 1.39e-07; PValue = 8e-09; mean CPM = 138.5; TIMP metallopeptidase inhibitor 2" ID="ID_195318261" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP17: 2.85-fold Down; FDR = 4.1e-07; PValue = 2.67e-08; mean CPM = 5.440; matrix metallopeptidase 17 (membrane-inserted)" ID="ID_1233150235" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP23B: 3.52-fold Down; FDR = 9.11e-07; PValue = 6.49e-08; mean CPM = 3.818; matrix metallopeptidase 23B" ID="ID_1106136310" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP16: 1.93-fold Down; FDR = 6.34e-06; PValue = 5.64e-07; mean CPM = 13.80; matrix metallopeptidase 16 (membrane-inserted)" ID="ID_1114032018" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP11: 2.57-fold Down; FDR = 3.12e-05; PValue = 3.32e-06; mean CPM = 36.98; matrix metallopeptidase 11 (stromelysin 3)" ID="ID_1374887888" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP10: 4.95-fold Down; FDR = 4.35e-05; PValue = 4.84e-06; mean CPM = 6.712; matrix metallopeptidase 10 (stromelysin 2)" ID="ID_188522599" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BSG: 1.3-fold Down; FDR = 0.00161; PValue = 0.00029; mean CPM = 272.4; basigin (Ok blood group)" ID="ID_1459580873" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP28: 1.9-fold Down; FDR = 0.0021; PValue = 0.000391; mean CPM = 3.380; matrix metallopeptidase 28" ID="ID_570492491" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP9: 4.49-fold Down; FDR = 0.00222; PValue = 0.000419; mean CPM = 6.597; matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)" ID="ID_915696035" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP1: 3.27-fold Down; FDR = 0.00611; PValue = 0.00133; mean CPM = 110.4; matrix metallopeptidase 1 (interstitial collagenase)" ID="ID_1373930819" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP3: 3.29-fold Down; FDR = 0.104; PValue = 0.037; mean CPM = 81.12; matrix metallopeptidase 3 (stromelysin 1, progelatinase)" ID="ID_771049348" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP24: 1.9-fold Down; FDR = 0.123; PValue = 0.045; mean CPM = 1.742; matrix metallopeptidase 24 (membrane-inserted)" ID="ID_1174537610" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP19: 1.25-fold Down; FDR = 0.131; PValue = 0.0488; mean CPM = 10.93; matrix metallopeptidase 19" ID="ID_1278021534" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP21: 1.25-fold Down; FDR = 0.683; PValue = 0.393; mean CPM = 1.578; matrix metallopeptidase 21" ID="ID_377369523" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP8: 1.48-fold Up; FDR = 0.814; PValue = 0.511; mean CPM = 0.8081; matrix metallopeptidase 8 (neutrophil collagenase)" ID="ID_491260521" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TCF20: 1.04-fold Up; FDR = 0.888; PValue = 0.611; mean CPM = 90.07; transcription factor 20 (AR1)" ID="ID_1330073433" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_1092456231" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP7: 1.39-fold Down; FDR = 0.89; PValue = 0.613; mean CPM = 0.8356; Uncharacterized protein" ID="ID_1722483615" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP15: 1.08-fold Up; FDR = 0.897; PValue = 0.622; mean CPM = 7.415; matrix metallopeptidase 15 (membrane-inserted)" ID="ID_967114592" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP27: 1.21-fold Up; FDR = 0.919; PValue = 0.72; mean CPM = 0.8172; matrix metallopeptidase 27" ID="ID_151992119" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP25: 1.24-fold Up; FDR = 0.939; PValue = 0.753; mean CPM = 0.8461; matrix metallopeptidase 25" ID="ID_64095022" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP20: 1.04-fold Down; FDR = 1; PValue = 0.947; mean CPM = 0.8723; matrix metallopeptidase 20" ID="ID_1544390128" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP2: No Change; FDR = 1; PValue = 0.976; mean CPM = 210.3; matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)" ID="ID_1499484253" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP26: No Change; FDR = 1; PValue = 0.998; mean CPM = 0.8086; matrix metallopeptidase 26" ID="ID_386748757" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Serotonin Receptor 2 and STAT3 Signaling (WP733:Rev45035): FDR = 8.36e-13, PValue = 1.35e-13" ID="ID_497866425" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_78192754" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_1717713355" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HTR2A: 1.18-fold Up; FDR = 0.253; PValue = 0.11; mean CPM = 70.26; 5-hydroxytryptamine (serotonin) receptor 2A" ID="ID_948348080" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAQ: 1.05-fold Down; FDR = 0.889; PValue = 0.611; mean CPM = 9.623; Guanine nucleotide-binding protein G(Q) subunit alpha; Uncharacterized protein" ID="ID_218483739" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAQ: No Change; FDR = 1; PValue = 0.975; mean CPM = 15.20; guanine nucleotide binding protein (G protein), q polypeptide" ID="ID_727285096" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Integrin-mediated cell adhesion (WP185:Rev44862): FDR = 1.19e-12, PValue = 1.99e-13" ID="ID_496459409" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="ITGA5: 3.79-fold Down; FDR = 1.33e-14; PValue = 1.48e-16; mean CPM = 1237; integrin, alpha 5 (fibronectin receptor, alpha polypeptide)" ID="ID_1271037744" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VCL: 2.48-fold Down; FDR = 5.94e-13; PValue = 9.16e-15; mean CPM = 1013; vinculin" ID="ID_1714112516" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAV: 2.64-fold Down; FDR = 6.04e-11; PValue = 1.51e-12; mean CPM = 337.3; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)" ID="ID_191779380" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNS1: 2.51-fold Down; FDR = 1.03e-10; PValue = 2.68e-12; mean CPM = 434.5; tensin 1" ID="ID_1896769683" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SORBS1: 2.91-fold Down; FDR = 1.08e-10; PValue = 2.84e-12; mean CPM = 81.82; sorbin and SH3 domain containing 1" ID="ID_1205486489" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB8: 3.97-fold Up; FDR = 6.37e-10; PValue = 2.06e-11; mean CPM = 11.37; integrin, beta 8" ID="ID_1335797072" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA2: 2.84-fold Up; FDR = 7.38e-10; PValue = 2.42e-11; mean CPM = 176.3; integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)" ID="ID_1472668037" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB3: 5.02-fold Down; FDR = 1.72e-09; PValue = 6.17e-11; mean CPM = 43.21; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)" ID="ID_1818760530" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_887776549" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB5: 1.61-fold Down; FDR = 8.23e-09; PValue = 3.47e-10; mean CPM = 471.0; integrin, beta 5" ID="ID_479904567" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA10: 4.95-fold Down; FDR = 1.77e-08; PValue = 8.13e-10; mean CPM = 5.184; integrin, alpha 10" ID="ID_1690217906" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA8: 4.04-fold Down; FDR = 5.89e-08; PValue = 3.12e-09; mean CPM = 145.8; integrin, alpha 8" ID="ID_432720971" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ILK: 1.53-fold Down; FDR = 5.97e-08; PValue = 3.17e-09; mean CPM = 256.9; integrin-linked kinase" ID="ID_445071537" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1B: 1.55-fold Up; FDR = 2.39e-07; PValue = 1.46e-08; mean CPM = 135.3; Ras-related protein Rap-1b; Ras-related protein Rap-1b isoform 1; Uncharacterized protein" ID="ID_441780993" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_434784457" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARHGEF7: 1.72-fold Down; FDR = 6.46e-07; PValue = 4.4e-08; mean CPM = 53.66; Rho guanine nucleotide exchange factor (GEF) 7" ID="ID_349251796" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_1971921516" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC3: 1.68-fold Down; FDR = 2.72e-06; PValue = 2.19e-07; mean CPM = 13.98; ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)" ID="ID_1234016484" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K3: 1.45-fold Down; FDR = 7.01e-06; PValue = 6.34e-07; mean CPM = 180.1; mitogen-activated protein kinase kinase 3" ID="ID_720762986" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1928389781" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAPNS1: 1.4-fold Down; FDR = 6.09e-05; PValue = 7.11e-06; mean CPM = 239.1; calpain, small subunit 1" ID="ID_164565567" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K5: 1.55-fold Up; FDR = 7.6e-05; PValue = 9.12e-06; mean CPM = 16.82; mitogen-activated protein kinase kinase 5" ID="ID_123600572" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCAR1: 1.36-fold Up; FDR = 0.000193; PValue = 2.61e-05; mean CPM = 210.4; breast cancer anti-estrogen resistance 1" ID="ID_455537743" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C17orf57: 5.51-fold Down; FDR = 0.000238; PValue = 3.33e-05; mean CPM = 1.571; EF-hand domain-containing protein C17orf57" ID="ID_336718836" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAPN5: 1.67-fold Down; FDR = 0.00033; PValue = 4.79e-05; mean CPM = 5.965; calpain 5" ID="ID_1378053369" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA3: 1.34-fold Down; FDR = 0.000518; PValue = 7.96e-05; mean CPM = 126.8; integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)" ID="ID_1102253538" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZYX: 1.29-fold Down; FDR = 0.00237; PValue = 0.00045; mean CPM = 287.5; Uncharacterized protein" ID="ID_1443831007" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK3: 3.55-fold Up; FDR = 0.00273; PValue = 0.000527; mean CPM = 1.136; p21 protein (Cdc42/Rac)-activated kinase 3" ID="ID_503920743" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1B: 1.43-fold Up; FDR = 0.00346; PValue = 0.000693; mean CPM = 12.81; RAP1B, member of RAS oncogene family" ID="ID_915297960" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB4: 1.66-fold Down; FDR = 0.00369; PValue = 0.000748; mean CPM = 5.291; integrin, beta 4" ID="ID_1445388321" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV3: 1.82-fold Down; FDR = 0.00463; PValue = 0.000973; mean CPM = 7.044; vav 3 guanine nucleotide exchange factor" ID="ID_1024230219" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAV1: 1.33-fold Down; FDR = 0.00575; PValue = 0.00125; mean CPM = 228.7; caveolin-1" ID="ID_137139664" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VASP: 1.26-fold Down; FDR = 0.00581; PValue = 0.00126; mean CPM = 250.9; vasodilator-stimulated phosphoprotein" ID="ID_1193448494" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_973058756" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAPN7: 1.26-fold Up; FDR = 0.00973; PValue = 0.00227; mean CPM = 38.08; calpain 7" ID="ID_1745958210" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLN1: 1.26-fold Down; FDR = 0.0101; PValue = 0.00238; mean CPM = 1820; talin 1" ID="ID_1906251342" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FYN: 1.22-fold Up; FDR = 0.0156; PValue = 0.00393; mean CPM = 92.94; FYN oncogene related to SRC, FGR, YES" ID="ID_950879005" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB2: 1.55-fold Down; FDR = 0.0187; PValue = 0.00485; mean CPM = 34.87; Integrin beta" ID="ID_466810143" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA2B: 1.71-fold Down; FDR = 0.0187; PValue = 0.00486; mean CPM = 2.655; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)" ID="ID_1179256467" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_718166067" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_82458601" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC2: 2.96-fold Up; FDR = 0.0309; PValue = 0.00872; mean CPM = 0.9737; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)" ID="ID_1902593908" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDPK1: 1.24-fold Down; FDR = 0.0361; PValue = 0.0105; mean CPM = 17.53; 3-phosphoinositide dependent protein kinase-1" ID="ID_692388512" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK6: 3.06-fold Down; FDR = 0.04; PValue = 0.0118; mean CPM = 0.9224; p21 protein (Cdc42/Rac)-activated kinase 6" ID="ID_1549186572" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_755689059" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK4: 1.21-fold Down; FDR = 0.0756; PValue = 0.0252; mean CPM = 16.78; p21 protein (Cdc42/Rac)-activated kinase 4" ID="ID_1205422869" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB1: 1.23-fold Up; FDR = 0.0759; PValue = 0.0253; mean CPM = 2700; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)" ID="ID_1015002160" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1A: 1.17-fold Up; FDR = 0.0888; PValue = 0.0304; mean CPM = 37.16; RAP1A, member of RAS oncogene family" ID="ID_1879034305" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK2: 1.15-fold Up; FDR = 0.134; PValue = 0.0502; mean CPM = 89.49; p21 protein (Cdc42/Rac)-activated kinase 2" ID="ID_51968788" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAPN11: 1.86-fold Down; FDR = 0.159; PValue = 0.0616; mean CPM = 1.173; calpain 11" ID="ID_588127310" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ROCK2: 1.14-fold Up; FDR = 0.166; PValue = 0.065; mean CPM = 247.7; Rho-associated, coiled-coil containing protein kinase 2" ID="ID_636542395" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1519077350" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_549485124" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BRAF: 1.14-fold Down; FDR = 0.228; PValue = 0.0964; mean CPM = 24.98; v-raf murine sarcoma viral oncogene homolog B1" ID="ID_43352344" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAV2: 1.14-fold Down; FDR = 0.24; PValue = 0.103; mean CPM = 25.69; caveolin 2" ID="ID_525824247" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_616118548" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2: 1.1-fold Up; FDR = 0.394; PValue = 0.191; mean CPM = 102.5; PTK2 protein tyrosine kinase 2" ID="ID_970312945" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHO: 1.78-fold Down; FDR = 0.395; PValue = 0.191; mean CPM = 0.8794; rhodopsin" ID="ID_662992115" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK6: 1.34-fold Up; FDR = 0.407; PValue = 0.198; mean CPM = 2.043; mitogen-activated protein kinase 6" ID="ID_162375554" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK12: 1.19-fold Down; FDR = 0.422; PValue = 0.208; mean CPM = 6.569; mitogen-activated protein kinase 12" ID="ID_1171358801" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYLK2: 1.56-fold Down; FDR = 0.541; PValue = 0.288; mean CPM = 0.9259; myosin light chain kinase 2" ID="ID_836986104" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA1: 1.1-fold Down; FDR = 0.57; PValue = 0.308; mean CPM = 422.3; integrin, alpha 1" ID="ID_1086867429" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC3: 1.37-fold Down; FDR = 0.584; PValue = 0.318; mean CPM = 1.193; SHC-transforming protein 3; Uncharacterized protein" ID="ID_538785284" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA9: 1.3-fold Down; FDR = 0.595; PValue = 0.326; mean CPM = 1.685; integrin, alpha 9" ID="ID_47657186" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDC42: 1.07-fold Down; FDR = 0.608; PValue = 0.335; mean CPM = 91.67; cell division cycle 42" ID="ID_691983075" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSK: 1.06-fold Down; FDR = 0.673; PValue = 0.386; mean CPM = 45.36; c-src tyrosine kinase" ID="ID_1910170285" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA4: 1.16-fold Down; FDR = 0.722; PValue = 0.425; mean CPM = 5.425; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)" ID="ID_329058136" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAM: 1.44-fold Down; FDR = 0.73; PValue = 0.432; mean CPM = 0.9052; integrin, alpha M (complement component 3 receptor 3 subunit)" ID="ID_180312302" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB6: 1.4-fold Down; FDR = 0.732; PValue = 0.434; mean CPM = 0.9377; Integrin beta" ID="ID_1383111735" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAPGEF1: 1.05-fold Down; FDR = 0.763; PValue = 0.462; mean CPM = 70.38; Rap guanine nucleotide exchange factor (GEF) 1" ID="ID_592644131" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRK: 1.05-fold Up; FDR = 0.791; PValue = 0.488; mean CPM = 59.92; v-crk sarcoma virus CT10 oncogene homolog (avian)" ID="ID_1081970703" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DOCK1: 1.05-fold Up; FDR = 0.825; PValue = 0.524; mean CPM = 165.2; dedicator of cytokinesis 1" ID="ID_932386096" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAD: 1.66-fold Down; FDR = 0.85; PValue = 0.56; mean CPM = 0.8625; integrin, alpha D" ID="ID_800453716" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1329059721" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK7: 1.04-fold Down; FDR = 0.899; PValue = 0.632; mean CPM = 16.93; Uncharacterized protein" ID="ID_460348693" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GIT2: 1.03-fold Up; FDR = 0.903; PValue = 0.641; mean CPM = 56.52; G protein-coupled receptor kinase interacting ArfGAP 2" ID="ID_1756992913" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK1: 1.03-fold Down; FDR = 0.911; PValue = 0.705; mean CPM = 18.65; p21 protein (Cdc42/Rac)-activated kinase 1" ID="ID_1364110039" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAPN6: 1.12-fold Up; FDR = 0.914; PValue = 0.71; mean CPM = 1.245; calpain 6" ID="ID_1486607391" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAPN3: 1.07-fold Down; FDR = 0.921; PValue = 0.724; mean CPM = 6.384; calpain 3, (p94)" ID="ID_1575975136" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_228150741" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_265262038" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAPN9: 1.14-fold Down; FDR = 1; PValue = 0.893; mean CPM = 0.8458; calpain 9" ID="ID_1088272689" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK4: 1.19-fold Down; FDR = 1; PValue = 0.95; mean CPM = 0.8611; mitogen-activated protein kinase 4" ID="ID_955759535" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAL: 1.03-fold Up; FDR = 1; PValue = 0.95; mean CPM = 1.035; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)" ID="ID_60618163" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB7: 1.01-fold Down; FDR = 1; PValue = 0.968; mean CPM = 2.025; integrin, beta 7" ID="ID_220948252" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV2: No Change; FDR = 1; PValue = 0.976; mean CPM = 25.65; vav 2 guanine nucleotide exchange factor" ID="ID_583131018" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAV3: 1.02-fold Down; FDR = 1; PValue = 0.98; mean CPM = 0.7970; caveolin 3" ID="ID_1794578881" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAPN10: No Change; FDR = 1; PValue = 0.991; mean CPM = 32.48; calpain 10" ID="ID_1213052069" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Selenium Pathway (WP15:Rev45021): FDR = 1.44e-12, PValue = 2.47e-13" ID="ID_64121814" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="ICAM1: 24.6-fold Up; FDR = 2.39e-17; PValue = 1.64e-19; mean CPM = 232.4; intercellular adhesion molecule 1" ID="ID_1525880365" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL2: 24.6-fold Up; FDR = 1.83e-15; PValue = 1.69e-17; mean CPM = 668.2; Macaca mulatta chemokine (C-C motif) ligand 2 (CCL2), mRNA." ID="ID_1318907649" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOD1: 1.67-fold Up; FDR = 3.83e-10; PValue = 1.17e-11; mean CPM = 160.0; superoxide dismutase 1, soluble" ID="ID_745423809" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAT: 1.75-fold Up; FDR = 1.21e-09; PValue = 4.14e-11; mean CPM = 42.72; catalase" ID="ID_1682349420" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INSR: 1.93-fold Down; FDR = 1.24e-08; PValue = 5.48e-10; mean CPM = 118.3; insulin receptor" ID="ID_1705767884" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOD2: 4.88-fold Up; FDR = 1.73e-08; PValue = 7.93e-10; mean CPM = 558.4; superoxide dismutase 2, mitochondrial" ID="ID_719990533" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1983981503" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ABCA1: 2.65-fold Up; FDR = 5.3e-07; PValue = 3.52e-08; mean CPM = 203.4; ATP-binding cassette, sub-family A (ABC1), member 1" ID="ID_994874365" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RFK: 2-fold Up; FDR = 1.24e-05; PValue = 1.19e-06; mean CPM = 7.534; riboflavin kinase" ID="ID_115462098" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_954541904" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRDX3: 1.35-fold Up; FDR = 0.000161; PValue = 2.12e-05; mean CPM = 79.39; peroxiredoxin 3" ID="ID_496420020" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KYNU: 1.76-fold Up; FDR = 0.000177; PValue = 2.37e-05; mean CPM = 157.2; kynureninase (L-kynurenine hydrolase)" ID="ID_1703989580" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTGS2: 2.02-fold Up; FDR = 0.000254; PValue = 3.59e-05; mean CPM = 314.5; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)" ID="ID_621968169" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SCARB1: 1.44-fold Down; FDR = 0.000494; PValue = 7.55e-05; mean CPM = 14.81; scavenger receptor class B, member 1" ID="ID_517770519" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRDX2: 1.31-fold Down; FDR = 0.00103; PValue = 0.000174; mean CPM = 49.31; Peroxiredoxin-2; Peroxiredoxin-2 isoform a; Uncharacterized protein" ID="ID_119223602" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SERPINE1: 1.58-fold Down; FDR = 0.00232; PValue = 0.000438; mean CPM = 5294; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1" ID="ID_1804190326" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOD3: 1.7-fold Down; FDR = 0.00506; PValue = 0.00107; mean CPM = 36.72; superoxide dismutase 3, extracellular" ID="ID_862807277" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FLAD1: 1.27-fold Up; FDR = 0.00617; PValue = 0.00135; mean CPM = 31.00; Uncharacterized protein" ID="ID_461131592" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTH: 1.72-fold Up; FDR = 0.00927; PValue = 0.00216; mean CPM = 23.63; cystathionase (cystathionine gamma-lyase)" ID="ID_1391703083" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRDX2: 1.32-fold Down; FDR = 0.0159; PValue = 0.00402; mean CPM = 11.74; peroxiredoxin 2" ID="ID_89477854" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSR: 1.26-fold Up; FDR = 0.0263; PValue = 0.00721; mean CPM = 28.15; glutathione reductase" ID="ID_1296394851" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ALOX5AP: 2.75-fold Down; FDR = 0.0327; PValue = 0.00932; mean CPM = 1.072; arachidonate 5-lipoxygenase-activating protein" ID="ID_1467471580" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLAT: 1.37-fold Down; FDR = 0.034; PValue = 0.00976; mean CPM = 76.44; plasminogen activator, tissue" ID="ID_454103607" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_901819610" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SERPINA3: 1.78-fold Down; FDR = 0.0544; PValue = 0.017; mean CPM = 6.499; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3" ID="ID_417664445" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTR: 1.18-fold Down; FDR = 0.0633; PValue = 0.0203; mean CPM = 75.25; 5-methyltetrahydrofolate-homocysteine methyltransferase" ID="ID_141100043" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRDX1: 1.17-fold Up; FDR = 0.104; PValue = 0.0366; mean CPM = 384.6; peroxiredoxin 1" ID="ID_1144361141" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APOA1: 2.5-fold Down; FDR = 0.104; PValue = 0.0368; mean CPM = 0.9574; apolipoprotein A-I" ID="ID_1320861207" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="F2: 1.67-fold Down; FDR = 0.132; PValue = 0.0494; mean CPM = 1.475; coagulation factor II (thrombin)" ID="ID_367294403" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TXN: 1.14-fold Up; FDR = 0.184; PValue = 0.0741; mean CPM = 93.12; thioredoxin" ID="ID_937162399" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TXN: 1.15-fold Up; FDR = 0.211; PValue = 0.0875; mean CPM = 147.9; Macaca mulatta thioredoxin (TXN), mRNA." ID="ID_1349321180" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRDX5: 1.13-fold Up; FDR = 0.22; PValue = 0.0922; mean CPM = 162.7; peroxiredoxin 5" ID="ID_684420315" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTHFR: 1.17-fold Down; FDR = 0.235; PValue = 0.1; mean CPM = 12.57; methylenetetrahydrofolate reductase (NAD(P)H)" ID="ID_994759942" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PNPO: 1.15-fold Down; FDR = 0.245; PValue = 0.105; mean CPM = 16.00; pyridoxamine 5'-phosphate oxidase" ID="ID_160850956" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTGS1: 1.18-fold Down; FDR = 0.368; PValue = 0.175; mean CPM = 116.4; Uncharacterized protein" ID="ID_873343344" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ALOX5: 1.56-fold Up; FDR = 0.49; PValue = 0.251; mean CPM = 0.9979; arachidonate 5-lipoxygenase" ID="ID_1917316625" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XDH: 1.62-fold Up; FDR = 0.495; PValue = 0.255; mean CPM = 0.9209; xanthine dehydrogenase" ID="ID_1909033119" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KMO: 1.52-fold Up; FDR = 0.643; PValue = 0.362; mean CPM = 0.8796; Kynurenine 3-monooxygenase" ID="ID_1653633325" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_886614570" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APOB: 1.36-fold Down; FDR = 0.723; PValue = 0.426; mean CPM = 0.9779; apolipoprotein B (including Ag(x) antigen)" ID="ID_1934132856" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRDX4: 1.06-fold Down; FDR = 0.726; PValue = 0.428; mean CPM = 70.33; peroxiredoxin 4" ID="ID_1424954519" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LDLR: 1.07-fold Down; FDR = 0.854; PValue = 0.567; mean CPM = 167.3; low density lipoprotein receptor" ID="ID_218353954" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HBB: 1.21-fold Up; FDR = 0.883; PValue = 0.603; mean CPM = 0.9754; hemoglobin, beta" ID="ID_1572164337" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_300816192" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_1897646007" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ALOX15B: 1.32-fold Up; FDR = 0.906; PValue = 0.67; mean CPM = 0.8315; arachidonate 15-lipoxygenase, type B" ID="ID_792062244" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="F7: 1.07-fold Down; FDR = 0.921; PValue = 0.723; mean CPM = 2.252; coagulation factor VII (serum prothrombin conversion accelerator)" ID="ID_739331436" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HBA1: 1.14-fold Up; FDR = 0.929; PValue = 0.738; mean CPM = 0.8217; hemoglobin, alpha 1" ID="ID_1811534373" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLG: 1.41-fold Down; FDR = 0.937; PValue = 0.751; mean CPM = 0.8390; plasminogen" ID="ID_151003868" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HBA2: 1.16-fold Up; FDR = 0.942; PValue = 0.76; mean CPM = 0.8111; hemoglobin, alpha 2" ID="ID_37234228" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ALB: 1.05-fold Down; FDR = 1; PValue = 0.98; mean CPM = 0.8186; Serum albumin" ID="ID_45052257" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRP: No Change; FDR = 1; PValue = 1; mean CPM = 0.7818; Uncharacterized protein" ID="ID_1259420019" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Alpha 6 Beta 4 signaling pathway (WP244:Rev44947): FDR = 1.6e-12, PValue = 2.84e-13" ID="ID_1381483455" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="LAMC1: 2.28-fold Down; FDR = 6.46e-13; PValue = 1.01e-14; mean CPM = 812.1; laminin, gamma 1 (formerly LAMB2)" ID="ID_1153043448" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016591: 4.2-fold Down; FDR = 1.3e-11; PValue = 2.78e-13; mean CPM = 34.90; Uncharacterized protein" ID="ID_1374849197" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016587: 4.92-fold Down; FDR = 1.6e-11; PValue = 3.5e-13; mean CPM = 51.70; Uncharacterized protein" ID="ID_847807100" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRS1: 2.78-fold Up; FDR = 7.67e-09; PValue = 3.19e-10; mean CPM = 26.55; Uncharacterized protein" ID="ID_1890276795" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_344779070" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMC2: 2.28-fold Down; FDR = 9.83e-06; PValue = 9.24e-07; mean CPM = 16.99; laminin, gamma 2" ID="ID_1839409288" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB2: 1.48-fold Down; FDR = 0.000398; PValue = 5.93e-05; mean CPM = 695.6; laminin, beta 2 (laminin S)" ID="ID_1333962763" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTOR: 1.3-fold Down; FDR = 0.00117; PValue = 0.000201; mean CPM = 107.5; mechanistic target of rapamycin (serine/threonine kinase)" ID="ID_1982281629" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHOA: 1.28-fold Down; FDR = 0.00295; PValue = 0.000575; mean CPM = 277.8; ras homolog gene family, member A" ID="ID_945169240" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB4: 1.66-fold Down; FDR = 0.00369; PValue = 0.000748; mean CPM = 5.291; integrin, beta 4" ID="ID_90021470" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_80658192" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1692221674" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_987826817" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF4EBP1: 1.23-fold Up; FDR = 0.0729; PValue = 0.0241; mean CPM = 40.55; eukaryotic translation initiation factor 4E binding protein 1" ID="ID_1544115682" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_542502752" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014969: 1.93-fold Down; FDR = 0.303; PValue = 0.137; mean CPM = 0.9384; Uncharacterized protein" ID="ID_471650695" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB3: 1.6-fold Down; FDR = 0.303; PValue = 0.137; mean CPM = 1.445; laminin, beta 3" ID="ID_184099599" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2: 1.1-fold Up; FDR = 0.394; PValue = 0.191; mean CPM = 102.5; PTK2 protein tyrosine kinase 2" ID="ID_123101144" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1774531720" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_123018828" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_9962951" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GAB1: 1.1-fold Up; FDR = 0.635; PValue = 0.356; mean CPM = 14.59; GRB2-associated binding protein 1" ID="ID_1393158843" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCD: 1.06-fold Up; FDR = 0.696; PValue = 0.404; mean CPM = 37.45; protein kinase C, delta" ID="ID_556503519" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014966: 1.43-fold Down; FDR = 0.72; PValue = 0.423; mean CPM = 0.9009; Uncharacterized protein" ID="ID_29142851" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_1329979384" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Hypothetical Network for Drug Addiction (WP666:Rev45365): FDR = 2.09e-12, PValue = 3.81e-13" ID="ID_1304737936" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="GRIA1: 7.88-fold Down; FDR = 3.44e-12; PValue = 6.37e-14; mean CPM = 5.809; glutamate receptor, ionotropic, AMPA 1" ID="ID_1034488112" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPA1: 2.1-fold Up; FDR = 1.04e-11; PValue = 2.17e-13; mean CPM = 69.99; Uncharacterized protein" ID="ID_1604357782" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_605448128" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NISCH: 1.41-fold Down; FDR = 0.000122; PValue = 1.55e-05; mean CPM = 78.46; nischarin" ID="ID_777568363" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCE: 1.73-fold Up; FDR = 0.00013; PValue = 1.67e-05; mean CPM = 10.87; protein kinase C, epsilon" ID="ID_360527119" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACA: 1.36-fold Down; FDR = 0.000167; PValue = 2.22e-05; mean CPM = 37.75; protein kinase, cAMP-dependent, catalytic, alpha" ID="ID_167441125" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACTA1: 5.36-fold Down; FDR = 0.000251; PValue = 3.52e-05; mean CPM = 5.880; Uncharacterized protein" ID="ID_673188747" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRIN2C: 1.94-fold Down; FDR = 0.00298; PValue = 0.000582; mean CPM = 2.673; glutamate receptor, ionotropic, N-methyl D-aspartate 2C" ID="ID_1248963409" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRIN2D: 2.02-fold Down; FDR = 0.00378; PValue = 0.00077; mean CPM = 3.190; glutamate receptor, ionotropic, N-methyl D-aspartate 2D" ID="ID_317162032" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAMK2B: 3.82-fold Down; FDR = 0.00536; PValue = 0.00115; mean CPM = 1.542; calcium/calmodulin-dependent protein kinase II beta" ID="ID_71608355" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPA1: 2.24-fold Up; FDR = 0.00738; PValue = 0.00165; mean CPM = 1.897; pyrophosphatase (inorganic) 1" ID="ID_1832101236" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_259880779" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KRIT1: 1.23-fold Up; FDR = 0.0264; PValue = 0.00726; mean CPM = 32.04; KRIT1, ankyrin repeat containing" ID="ID_1012996336" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRIN2B: 3.63-fold Down; FDR = 0.0282; PValue = 0.00782; mean CPM = 1.577; glutamate receptor, ionotropic, N-methyl D-aspartate 2B" ID="ID_1287537375" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB1: 1.21-fold Up; FDR = 0.0313; PValue = 0.00884; mean CPM = 36.07; cAMP responsive element binding protein 1" ID="ID_804433047" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TERF2IP: 1.15-fold Down; FDR = 0.12; PValue = 0.0439; mean CPM = 46.09; telomeric repeat binding factor 2, interacting protein" ID="ID_1728082400" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRIN2A: 1.69-fold Down; FDR = 0.433; PValue = 0.214; mean CPM = 0.9509; glutamate receptor, ionotropic, N-methyl D-aspartate 2A" ID="ID_954313194" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1105361549" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GJB7: 1.38-fold Up; FDR = 0.651; PValue = 0.369; mean CPM = 1.104; gap junction protein, beta 7, 25kDa" ID="ID_263156923" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAMK4: 1.9-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 0.8628; calcium/calmodulin-dependent protein kinase IV" ID="ID_428874800" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRM5: 1.51-fold Up; FDR = 0.665; PValue = 0.38; mean CPM = 0.9962; glutamate receptor, metabotropic 5" ID="ID_624301870" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRIA3: 1.17-fold Down; FDR = 0.725; PValue = 0.427; mean CPM = 3.864; glutamate receptor, ionotrophic, AMPA 3" ID="ID_1736069151" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DRD1: 1.79-fold Up; FDR = 0.736; PValue = 0.438; mean CPM = 0.8307; dopamine receptor D1" ID="ID_883423715" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRM1: 1.8-fold Down; FDR = 0.771; PValue = 0.469; mean CPM = 0.8322; glutamate receptor, metabotropic 1" ID="ID_794362915" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_215066394" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY8: 1.28-fold Up; FDR = 0.891; PValue = 0.614; mean CPM = 0.8757; adenylate cyclase 8 (brain)" ID="ID_801031228" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRIN1: 1.44-fold Up; FDR = 0.903; PValue = 0.646; mean CPM = 0.8658; glutamate receptor, ionotropic, N-methyl D-aspartate 1" ID="ID_110138115" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZHX2: 1.04-fold Down; FDR = 0.903; PValue = 0.659; mean CPM = 17.70; zinc fingers and homeoboxes 2" ID="ID_1573963312" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY1: 1.13-fold Down; FDR = 0.908; PValue = 0.682; mean CPM = 1.243; adenylate cyclase 1 (brain)" ID="ID_1584153441" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRIA4: 1.39-fold Down; FDR = 0.999; PValue = 0.857; mean CPM = 0.8683; glutamate receptor, ionotrophic, AMPA 4" ID="ID_556627743" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="SREBP signalling (WP1982:Rev44836): FDR = 5.52e-12, PValue = 1.04e-12" ID="ID_951180752" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="SEC13: 2.02-fold Down; FDR = 8.77e-14; PValue = 1.14e-15; mean CPM = 134.4; SEC13 homolog (S. cerevisiae)" ID="ID_334111180" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SREBF2: 2.26-fold Down; FDR = 4.11e-12; PValue = 7.71e-14; mean CPM = 92.78; sterol regulatory element binding transcription factor 2" ID="ID_641623598" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SEC24C: 1.43-fold Down; FDR = 6.31e-06; PValue = 5.62e-07; mean CPM = 145.8; SEC24 family, member C (S. cerevisiae)" ID="ID_275852303" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SCAP: 1.32-fold Down; FDR = 0.000539; PValue = 8.35e-05; mean CPM = 63.74; SREBF chaperone" ID="ID_1484805552" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SEC24B: 1.31-fold Up; FDR = 0.000722; PValue = 0.000116; mean CPM = 61.16; SEC24 family, member B (S. cerevisiae)" ID="ID_1700113005" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SEC23B: 1.3-fold Down; FDR = 0.00127; PValue = 0.000222; mean CPM = 65.68; Sec23 homolog B (S. cerevisiae)" ID="ID_953382753" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SEC31B: 1.49-fold Down; FDR = 0.00218; PValue = 0.00041; mean CPM = 7.632; SEC31 homolog B (S. cerevisiae)" ID="ID_278186614" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MBTPS2: 1.29-fold Up; FDR = 0.0116; PValue = 0.0028; mean CPM = 18.91; membrane-bound transcription factor peptidase, site 2" ID="ID_1984505809" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SP1: 1.23-fold Up; FDR = 0.0139; PValue = 0.00344; mean CPM = 75.49; Transcription factor Sp1 isoform a; Uncharacterized protein" ID="ID_1060650809" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB1: 1.21-fold Up; FDR = 0.0313; PValue = 0.00884; mean CPM = 36.07; cAMP responsive element binding protein 1" ID="ID_1358265335" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SEC23A: 1.2-fold Down; FDR = 0.0358; PValue = 0.0104; mean CPM = 245.8; Sec23 homolog A (S. cerevisiae)" ID="ID_440866465" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SEC24A: 1.17-fold Down; FDR = 0.0725; PValue = 0.0239; mean CPM = 88.13; SEC24 family, member A (S. cerevisiae)" ID="ID_1282864725" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MBTPS1: 1.15-fold Down; FDR = 0.127; PValue = 0.0467; mean CPM = 165.5; Uncharacterized protein" ID="ID_904467280" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFYA: 1.14-fold Up; FDR = 0.174; PValue = 0.069; mean CPM = 34.54; nuclear transcription factor Y, alpha" ID="ID_893458825" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SREBF1: 1.11-fold Down; FDR = 0.324; PValue = 0.149; mean CPM = 179.9; sterol regulatory element binding transcription factor 1" ID="ID_707419307" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SAR1B: 1.09-fold Up; FDR = 0.487; PValue = 0.25; mean CPM = 47.60; SAR1 homolog B (S. cerevisiae)" ID="ID_106672307" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SAR1A: 1.04-fold Down; FDR = 0.861; PValue = 0.576; mean CPM = 132.8; SAR1 homolog A (S. cerevisiae)" ID="ID_748621803" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KPNB1: 1.02-fold Down; FDR = 0.977; PValue = 0.82; mean CPM = 283.0; karyopherin (importin) beta 1" ID="ID_1085531014" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="TWEAK Signaling Pathway (WP2036:Rev44633): FDR = 7.59e-12, PValue = 1.46e-12" ID="ID_1266089935" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_72379125" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL2: 24.6-fold Up; FDR = 1.83e-15; PValue = 1.69e-17; mean CPM = 668.2; Macaca mulatta chemokine (C-C motif) ligand 2 (CCL2), mRNA." ID="ID_903556735" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC2: 1.96-fold Up; FDR = 1.01e-10; PValue = 2.62e-12; mean CPM = 53.58; baculoviral IAP repeat-containing 2" ID="ID_1417957045" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_1180761514" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_948751966" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL5: 6.74-fold Up; FDR = 2.65e-07; PValue = 1.64e-08; mean CPM = 30.35; chemokine (C-C motif) ligand 5" ID="ID_458485331" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_425159337" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_641248797" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_160005657" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF1: 2.6-fold Down; FDR = 1.48e-05; PValue = 1.46e-06; mean CPM = 20.19; TNF receptor-associated factor 1" ID="ID_162028539" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_622650056" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP9: 4.49-fold Down; FDR = 0.00222; PValue = 0.000419; mean CPM = 6.597; matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)" ID="ID_279236861" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_187943950" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF12A: 1.24-fold Down; FDR = 0.0133; PValue = 0.00326; mean CPM = 478.0; tumor necrosis factor receptor superfamily, member 12A" ID="ID_1667381670" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC1: 1.25-fold Up; FDR = 0.0159; PValue = 0.00403; mean CPM = 27.51; histone deacetylase 1" ID="ID_121762645" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1879872107" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1211449616" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_922833708" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTNNB1: 1.2-fold Up; FDR = 0.0498; PValue = 0.0153; mean CPM = 558.3; catenin (cadherin-associated protein), beta 1, 88kDa" ID="ID_908720642" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELB: 1.22-fold Down; FDR = 0.0606; PValue = 0.0193; mean CPM = 26.64; v-rel reticuloendotheliosis viral oncogene homolog B" ID="ID_759131865" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF12-TNFSF13: 1.27-fold Up; FDR = 0.0755; PValue = 0.0251; mean CPM = 8.814; TNFSF12-TNFSF13 readthrough" ID="ID_1987323141" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FADD: 1.18-fold Down; FDR = 0.0936; PValue = 0.0324; mean CPM = 30.89; Uncharacterized protein" ID="ID_1868158169" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_1325539981" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_158484288" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_787854378" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_652183468" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP7: 1.15-fold Up; FDR = 0.218; PValue = 0.0916; mean CPM = 21.49; caspase 7, apoptosis-related cysteine peptidase" ID="ID_404835464" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1709980702" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1772877703" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF3: 1.07-fold Up; FDR = 0.611; PValue = 0.338; mean CPM = 34.56; TNF receptor-associated factor 3" ID="ID_869885408" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_631916048" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF25: 1.2-fold Up; FDR = 0.772; PValue = 0.471; mean CPM = 1.687; tumor necrosis factor receptor superfamily, member 25" ID="ID_79429134" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD163: 1.24-fold Down; FDR = 0.785; PValue = 0.482; mean CPM = 1.694; Uncharacterized protein" ID="ID_1259041411" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1235594773" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_1131917495" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_237194754" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_159176596" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_1116978976" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Cytokines and Inflammatory Response (WP530:Rev41163): FDR = 1.03e-11, PValue = 2.05e-12" ID="ID_1821250179" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CSF1: 7.34-fold Up; FDR = 4.6e-20; PValue = 1.69e-22; mean CPM = 149.8; colony stimulating factor 1 (macrophage)" ID="ID_1363674910" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL15: 17.3-fold Up; FDR = 2.78e-17; PValue = 1.92e-19; mean CPM = 5.103; Macaca mulatta interleukin 15 (IL15), mRNA." ID="ID_680531470" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFA: 1.92-fold Down; FDR = 2.56e-07; PValue = 1.58e-08; mean CPM = 22.99; platelet-derived growth factor alpha polypeptide" ID="ID_212051564" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL1: 2.18-fold Up; FDR = 0.00609; PValue = 0.00133; mean CPM = 45.92; chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)" ID="ID_1750512912" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSF2: 2.96-fold Down; FDR = 0.0174; PValue = 0.00447; mean CPM = 73.98; colony stimulating factor 2 (granulocyte-macrophage)" ID="ID_1242934324" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSF3: 2.55-fold Up; FDR = 0.0701; PValue = 0.023; mean CPM = 72.12; colony stimulating factor 3 (granulocyte)" ID="ID_1469657885" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1A: 1.5-fold Up; FDR = 0.315; PValue = 0.144; mean CPM = 155.4; interleukin 1, alpha" ID="ID_944761611" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_1009652944" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNB1: 1.79-fold Up; FDR = 0.731; PValue = 0.433; mean CPM = 0.8526; interferon, beta 1, fibroblast" ID="ID_1068503768" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD4: 1.27-fold Up; FDR = 0.807; PValue = 0.503; mean CPM = 1.122; CD4 molecule" ID="ID_909410254" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_1644478301" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DRB: 1.28-fold Up; FDR = 0.898; PValue = 0.624; mean CPM = 0.8112; MHC class II antigen; Uncharacterized protein" ID="ID_1585103475" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_1443325472" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL4: 1.27-fold Down; FDR = 0.933; PValue = 0.745; mean CPM = 0.8077; interleukin 4" ID="ID_439803463" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB1: 1.02-fold Down; FDR = 0.936; PValue = 0.749; mean CPM = 62.61; transforming growth factor, beta 1" ID="ID_1672329314" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL13: 1.05-fold Up; FDR = 0.967; PValue = 0.805; mean CPM = 0.8212; interleukin 13" ID="ID_329734906" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12B: 1.07-fold Up; FDR = 0.983; PValue = 0.831; mean CPM = 0.8197; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)" ID="ID_15198231" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL5: 1.05-fold Down; FDR = 1; PValue = 0.862; mean CPM = 1.367; interleukin 5 (colony-stimulating factor, eosinophil)" ID="ID_982196609" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL10: 1.21-fold Down; FDR = 1; PValue = 0.964; mean CPM = 0.8614; interleukin 10" ID="ID_995837540" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2: 1.03-fold Up; FDR = 1; PValue = 0.998; mean CPM = 0.7974; interleukin 2" ID="ID_1546577832" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Complement and Coagulation Cascades (WP558:Rev45058): FDR = 2.86e-11, PValue = 5.81e-12" ID="ID_410120278" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="SERPING1: 17.2-fold Up; FDR = 2.79e-22; PValue = 6.42e-25; mean CPM = 499.3; serpin peptidase inhibitor, clade G (C1 inhibitor), member 1" ID="ID_1277941092" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C2: 4.8-fold Up; FDR = 3.21e-17; PValue = 2.26e-19; mean CPM = 200.3; Uncharacterized protein" ID="ID_58504158" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="F3: 5.59-fold Down; FDR = 3.39e-11; PValue = 8.05e-13; mean CPM = 79.22; coagulation factor III (thromboplastin, tissue factor)" ID="ID_1085847249" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLAU: 3.37-fold Down; FDR = 1.56e-10; PValue = 4.33e-12; mean CPM = 18.78; plasminogen activator, urokinase" ID="ID_1586848409" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C3: 5.35-fold Up; FDR = 5.79e-07; PValue = 3.91e-08; mean CPM = 19.68; complement component 3" ID="ID_313501935" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C3AR1: 4.66-fold Up; FDR = 1e-06; PValue = 7.26e-08; mean CPM = 15.65; complement component 3a receptor 1" ID="ID_590066824" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C5AR1: 3.36-fold Up; FDR = 3.05e-05; PValue = 3.23e-06; mean CPM = 14.55; complement component 5a receptor 1" ID="ID_896479241" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SERPINE1: 1.58-fold Down; FDR = 0.00232; PValue = 0.000438; mean CPM = 5294; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1" ID="ID_382125829" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SERPINF2: 1.59-fold Up; FDR = 0.00264; PValue = 0.000509; mean CPM = 24.23; serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2" ID="ID_785745334" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="F12: 2.67-fold Down; FDR = 0.00473; PValue = 0.000996; mean CPM = 1.586; coagulation factor XII (Hageman factor)" ID="ID_694166453" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PROS1: 1.31-fold Up; FDR = 0.0206; PValue = 0.00545; mean CPM = 20.23; protein S (alpha)" ID="ID_1720402129" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="F8: 1.86-fold Up; FDR = 0.0276; PValue = 0.00765; mean CPM = 1.839; coagulation factor VIII, procoagulant component" ID="ID_347452586" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLAT: 1.37-fold Down; FDR = 0.034; PValue = 0.00976; mean CPM = 76.44; plasminogen activator, tissue" ID="ID_1101129353" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SERPIND1: 2.04-fold Down; FDR = 0.046; PValue = 0.0139; mean CPM = 1.843; serpin peptidase inhibitor, clade D (heparin cofactor), member 1" ID="ID_1684432161" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C1QB: 2.62-fold Up; FDR = 0.0887; PValue = 0.0304; mean CPM = 1.092; complement component 1, q subcomponent, B chain" ID="ID_1884669327" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="F2: 1.67-fold Down; FDR = 0.132; PValue = 0.0494; mean CPM = 1.475; coagulation factor II (thrombin)" ID="ID_1406578129" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SERPINA1: 1.42-fold Up; FDR = 0.139; PValue = 0.0524; mean CPM = 32.29; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1" ID="ID_1846124173" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VWF: 1.42-fold Down; FDR = 0.174; PValue = 0.069; mean CPM = 24.05; von Willebrand factor" ID="ID_426673664" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="A2M: 1.33-fold Up; FDR = 0.181; PValue = 0.0726; mean CPM = 750.0; alpha-2-macroglobulin" ID="ID_1804565871" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLAUR: 1.19-fold Down; FDR = 0.199; PValue = 0.0819; mean CPM = 46.31; Uncharacterized protein" ID="ID_1128393673" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C1QC: 2.02-fold Up; FDR = 0.203; PValue = 0.0839; mean CPM = 1.322; complement component 1, q subcomponent, C chain" ID="ID_1872003295" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD46: 1.13-fold Down; FDR = 0.214; PValue = 0.0894; mean CPM = 70.85; Uncharacterized protein" ID="ID_781856841" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CR1: 1.99-fold Up; FDR = 0.225; PValue = 0.095; mean CPM = 0.9520; Uncharacterized protein" ID="ID_150692201" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MASP1: 1.46-fold Down; FDR = 0.264; PValue = 0.115; mean CPM = 4.467; mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)" ID="ID_1536182229" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SERPINC1: 1.74-fold Down; FDR = 0.398; PValue = 0.193; mean CPM = 0.9122; antithrombin-III" ID="ID_1762066296" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SERPINA5: 1.57-fold Down; FDR = 0.409; PValue = 0.199; mean CPM = 1.235; plasma serine protease inhibitor" ID="ID_854397668" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="F2R: 1.1-fold Up; FDR = 0.458; PValue = 0.23; mean CPM = 35.05; coagulation factor II (thrombin) receptor" ID="ID_931923493" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C9: 1.41-fold Up; FDR = 0.505; PValue = 0.262; mean CPM = 1.295; complement component 9" ID="ID_47605117" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MASP2: 1.23-fold Down; FDR = 0.546; PValue = 0.291; mean CPM = 3.073; mannan-binding lectin serine peptidase 2" ID="ID_668420901" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BDKRB1: 1.18-fold Up; FDR = 0.556; PValue = 0.298; mean CPM = 22.68; bradykinin receptor B1" ID="ID_1231652820" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TFPI: 1.09-fold Down; FDR = 0.606; PValue = 0.335; mean CPM = 64.96; tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)" ID="ID_1008819972" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CPB2: 1.43-fold Up; FDR = 0.695; PValue = 0.403; mean CPM = 0.9275; carboxypeptidase B2 (plasma)" ID="ID_1564639011" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KNG1: 1.76-fold Up; FDR = 0.746; PValue = 0.447; mean CPM = 0.8419; Uncharacterized protein" ID="ID_15798888" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="F9: 1.57-fold Down; FDR = 0.788; PValue = 0.485; mean CPM = 0.8079; coagulation factor IX" ID="ID_1775854905" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGB: 1.44-fold Down; FDR = 0.797; PValue = 0.494; mean CPM = 0.8074; fibrinogen beta chain" ID="ID_419827625" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C6: 1.72-fold Down; FDR = 0.856; PValue = 0.57; mean CPM = 0.8334; complement component 6" ID="ID_823860469" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="F10: 1.07-fold Down; FDR = 0.91; PValue = 0.693; mean CPM = 2.929; coagulation factor X" ID="ID_1852208090" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="F7: 1.07-fold Down; FDR = 0.921; PValue = 0.723; mean CPM = 2.252; coagulation factor VII (serum prothrombin conversion accelerator)" ID="ID_1420190380" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLG: 1.41-fold Down; FDR = 0.937; PValue = 0.751; mean CPM = 0.8390; plasminogen" ID="ID_682133369" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="F13B: 1.15-fold Up; FDR = 0.942; PValue = 0.759; mean CPM = 0.8085; coagulation factor XIII, B polypeptide" ID="ID_1348433680" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C8G: 1.15-fold Up; FDR = 0.978; PValue = 0.822; mean CPM = 0.8664; complement component 8, gamma polypeptide" ID="ID_1800164576" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APOA2: 1.13-fold Down; FDR = 0.993; PValue = 0.847; mean CPM = 0.8139; apolipoprotein A-II" ID="ID_60578618" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C7: 1.11-fold Up; FDR = 1; PValue = 0.883; mean CPM = 0.8197; complement component 7" ID="ID_1521525455" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THBD: 1.03-fold Up; FDR = 1; PValue = 0.943; mean CPM = 2.929; thrombomodulin" ID="ID_557821535" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CR2: 1.07-fold Down; FDR = 1; PValue = 0.997; mean CPM = 0.8253; complement component (3d/Epstein Barr virus) receptor 2" ID="ID_1714733546" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Nifedipine Activity (WP259:Rev45358): FDR = 3.45e-11, PValue = 7.19e-12" ID="ID_347496298" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="PTK2B: 3.54-fold Up; FDR = 1.24e-07; PValue = 7.07e-09; mean CPM = 5.971; PTK2B protein tyrosine kinase 2 beta" ID="ID_161147346" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1320932169" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PCNA: 1.34-fold Up; FDR = 0.00398; PValue = 0.000816; mean CPM = 112.1; PCNA antisense RNA (non-protein coding)" ID="ID_142616873" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_669851026" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="TSH signaling pathway (WP2032:Rev44635): FDR = 3.55e-11, PValue = 7.58e-12" ID="ID_1136555801" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_1501144585" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_848754789" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_1386009423" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND3: 2.27-fold Down; FDR = 8.38e-11; PValue = 2.15e-12; mean CPM = 86.90; cyclin D3" ID="ID_522214027" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1B: 1.64-fold Up; FDR = 1.22e-08; PValue = 5.39e-10; mean CPM = 32.96; Cyclin-dependent kinase inhibitor 1B; Uncharacterized protein" ID="ID_569882222" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RB1: 1.65-fold Up; FDR = 6.01e-08; PValue = 3.2e-09; mean CPM = 59.24; retinoblastoma 1" ID="ID_1188543467" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RALGDS: 2.6-fold Up; FDR = 2.12e-07; PValue = 1.28e-08; mean CPM = 47.88; ral guanine nucleotide dissociation stimulator" ID="ID_1972626868" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1B: 1.55-fold Up; FDR = 2.39e-07; PValue = 1.46e-08; mean CPM = 135.3; Ras-related protein Rap-1b; Ras-related protein Rap-1b isoform 1; Uncharacterized protein" ID="ID_1514744899" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1659702853" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCB1: 1.71-fold Up; FDR = 1.31e-06; PValue = 9.73e-08; mean CPM = 34.36; phospholipase C, beta 1 (phosphoinositide-specific)" ID="ID_1231497365" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_747323644" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K3: 1.45-fold Down; FDR = 7.01e-06; PValue = 6.34e-07; mean CPM = 180.1; mitogen-activated protein kinase kinase 3" ID="ID_57237176" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1R: 1.51-fold Down; FDR = 1.02e-05; PValue = 9.61e-07; mean CPM = 213.2; insulin-like growth factor 1 receptor" ID="ID_712739753" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1969531011" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAI1: 1.47-fold Up; FDR = 5.94e-05; PValue = 6.9e-06; mean CPM = 97.19; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1" ID="ID_362863262" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SCRIB: 1.37-fold Down; FDR = 0.000163; PValue = 2.15e-05; mean CPM = 68.59; scribbled homolog (Drosophila)" ID="ID_1475775237" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNA12: 1.32-fold Down; FDR = 0.000955; PValue = 0.00016; mean CPM = 33.75; Uncharacterized protein" ID="ID_1321094876" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTOR: 1.3-fold Down; FDR = 0.00117; PValue = 0.000201; mean CPM = 107.5; mechanistic target of rapamycin (serine/threonine kinase)" ID="ID_160089083" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAS1: 1.31-fold Down; FDR = 0.00158; PValue = 0.000283; mean CPM = 564.9; Uncharacterized protein" ID="ID_1154495012" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1B: 1.43-fold Up; FDR = 0.00346; PValue = 0.000693; mean CPM = 12.81; RAP1B, member of RAS oncogene family" ID="ID_273610316" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYL12B: 1.28-fold Up; FDR = 0.00408; PValue = 0.00084; mean CPM = 372.0; myosin, light chain 12B, regulatory" ID="ID_1979630692" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAI3: 1.26-fold Up; FDR = 0.00487; PValue = 0.00103; mean CPM = 113.8; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3" ID="ID_1094122971" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK2: 1.23-fold Down; FDR = 0.0194; PValue = 0.00507; mean CPM = 36.76; cyclin-dependent kinase 2" ID="ID_1759038746" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1213187015" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA1: 1.25-fold Down; FDR = 0.0241; PValue = 0.00652; mean CPM = 21.28; ribosomal protein S6 kinase, 90kDa, polypeptide 1" ID="ID_1557458768" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TTF1: 1.26-fold Up; FDR = 0.0246; PValue = 0.00667; mean CPM = 19.17; transcription termination factor, RNA polymerase I" ID="ID_1673051575" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_304300065" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_1838677357" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB1: 1.21-fold Up; FDR = 0.0313; PValue = 0.00884; mean CPM = 36.07; cAMP responsive element binding protein 1" ID="ID_1798493593" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDPK1: 1.24-fold Down; FDR = 0.0361; PValue = 0.0105; mean CPM = 17.53; 3-phosphoinositide dependent protein kinase-1" ID="ID_1676050835" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="E2F1: 1.44-fold Down; FDR = 0.0425; PValue = 0.0127; mean CPM = 8.857; E2F transcription factor 1" ID="ID_1399617315" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNA13: 1.25-fold Up; FDR = 0.0428; PValue = 0.0128; mean CPM = 15.41; guanine nucleotide binding protein (G protein), alpha 13" ID="ID_1969962300" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_104272035" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_1483878718" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1A: 1.17-fold Up; FDR = 0.0888; PValue = 0.0304; mean CPM = 37.16; RAP1A, member of RAS oncogene family" ID="ID_596119201" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_206135593" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG2: 1.64-fold Up; FDR = 0.117; PValue = 0.0421; mean CPM = 2.320; guanine nucleotide binding protein (G protein), gamma 2" ID="ID_1730192355" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KCNIP3: 1.82-fold Down; FDR = 0.133; PValue = 0.0498; mean CPM = 1.262; Kv channel interacting protein 3, calsenilin" ID="ID_1843989833" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAI2: 1.15-fold Down; FDR = 0.134; PValue = 0.0501; mean CPM = 356.3; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2" ID="ID_1921364007" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1023234978" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLD1: 1.24-fold Down; FDR = 0.162; PValue = 0.0634; mean CPM = 15.80; phospholipase D1, phosphatidylcholine-specific" ID="ID_268327834" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BRAF: 1.14-fold Down; FDR = 0.228; PValue = 0.0964; mean CPM = 24.98; v-raf murine sarcoma viral oncogene homolog B1" ID="ID_995709859" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNE1: 1.2-fold Up; FDR = 0.278; PValue = 0.123; mean CPM = 6.609; cyclin E1" ID="ID_1343390689" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_582718140" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RBL2: 1.09-fold Up; FDR = 0.445; PValue = 0.222; mean CPM = 47.90; retinoblastoma-like 2 (p130)" ID="ID_383129023" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_970937298" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNB1: 1.08-fold Down; FDR = 0.565; PValue = 0.305; mean CPM = 299.4; guanine nucleotide binding protein (G protein), beta polypeptide 1" ID="ID_70183240" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6: 1.08-fold Up; FDR = 0.584; PValue = 0.318; mean CPM = 892.5; ribosomal protein S6" ID="ID_1384759294" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APEX1: 1.04-fold Up; FDR = 0.858; PValue = 0.571; mean CPM = 95.24; APEX nuclease (multifunctional DNA repair enzyme) 1" ID="ID_1277458170" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY2: 1.18-fold Down; FDR = 0.864; PValue = 0.58; mean CPM = 1.755; adenylate cyclase 2 (brain)" ID="ID_526502133" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB1: 1.04-fold Up; FDR = 0.88; PValue = 0.6; mean CPM = 30.80; Uncharacterized protein" ID="ID_1714627273" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAQ: 1.05-fold Down; FDR = 0.889; PValue = 0.611; mean CPM = 9.623; Guanine nucleotide-binding protein G(Q) subunit alpha; Uncharacterized protein" ID="ID_937143757" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK4: 1.04-fold Up; FDR = 0.899; PValue = 0.626; mean CPM = 65.45; cyclin-dependent kinase 4" ID="ID_977079936" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TSHB: 1.13-fold Down; FDR = 0.911; PValue = 0.702; mean CPM = 0.7879; thyroid stimulating hormone, beta" ID="ID_1201009046" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_589473634" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TSHR: 1.44-fold Down; FDR = 0.963; PValue = 0.799; mean CPM = 0.8693; thyroid stimulating hormone receptor" ID="ID_1217398221" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TTF2: 1.02-fold Down; FDR = 1; PValue = 0.863; mean CPM = 16.60; transcription termination factor, RNA polymerase II" ID="ID_1330641099" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAO1: 1.1-fold Down; FDR = 1; PValue = 0.866; mean CPM = 0.8448; guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O" ID="ID_1877152254" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY3: 1.01-fold Up; FDR = 1; PValue = 0.871; mean CPM = 34.92; adenylate cyclase 3" ID="ID_1882817694" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAX8: 1.06-fold Down; FDR = 1; PValue = 0.878; mean CPM = 0.8841; paired box 8" ID="ID_978424412" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CGA: 1.01-fold Down; FDR = 1; PValue = 0.952; mean CPM = 0.8464; Glycoprotein hormones alpha chain" ID="ID_1338135081" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAQ: No Change; FDR = 1; PValue = 0.975; mean CPM = 15.20; guanine nucleotide binding protein (G protein), q polypeptide" ID="ID_1894460830" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Vitamin B12 Metabolism (WP1533:Rev45013): FDR = 4.99e-11, PValue = 1.09e-11" ID="ID_1956286708" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="ICAM1: 24.6-fold Up; FDR = 2.39e-17; PValue = 1.64e-19; mean CPM = 232.4; intercellular adhesion molecule 1" ID="ID_286076529" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL2: 24.6-fold Up; FDR = 1.83e-15; PValue = 1.69e-17; mean CPM = 668.2; Macaca mulatta chemokine (C-C motif) ligand 2 (CCL2), mRNA." ID="ID_1754462578" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOD1: 1.67-fold Up; FDR = 3.83e-10; PValue = 1.17e-11; mean CPM = 160.0; superoxide dismutase 1, soluble" ID="ID_1048591655" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INSR: 1.93-fold Down; FDR = 1.24e-08; PValue = 5.48e-10; mean CPM = 118.3; insulin receptor" ID="ID_1733676394" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOD2: 4.88-fold Up; FDR = 1.73e-08; PValue = 7.93e-10; mean CPM = 558.4; superoxide dismutase 2, mitochondrial" ID="ID_1044190014" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1743555383" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL5: 6.74-fold Up; FDR = 2.65e-07; PValue = 1.64e-08; mean CPM = 30.35; chemokine (C-C motif) ligand 5" ID="ID_1340908728" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ABCA1: 2.65-fold Up; FDR = 5.3e-07; PValue = 3.52e-08; mean CPM = 203.4; ATP-binding cassette, sub-family A (ABC1), member 1" ID="ID_1785085251" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_1021698390" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTRR: 1.38-fold Up; FDR = 0.000187; PValue = 2.52e-05; mean CPM = 32.85; 5-methyltetrahydrofolate-homocysteine methyltransferase reductase" ID="ID_1800315816" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SCARB1: 1.44-fold Down; FDR = 0.000494; PValue = 7.55e-05; mean CPM = 14.81; scavenger receptor class B, member 1" ID="ID_452731549" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SERPINE1: 1.58-fold Down; FDR = 0.00232; PValue = 0.000438; mean CPM = 5294; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1" ID="ID_96775145" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOD3: 1.7-fold Down; FDR = 0.00506; PValue = 0.00107; mean CPM = 36.72; superoxide dismutase 3, extracellular" ID="ID_223639221" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTH: 1.72-fold Up; FDR = 0.00927; PValue = 0.00216; mean CPM = 23.63; cystathionase (cystathionine gamma-lyase)" ID="ID_920954683" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TCN2: 1.6-fold Down; FDR = 0.0118; PValue = 0.00282; mean CPM = 5.020; transcobalamin II" ID="ID_685525098" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APOE: 1.75-fold Down; FDR = 0.0148; PValue = 0.00369; mean CPM = 24.21; apolipoprotein E" ID="ID_1550683532" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MUT: 1.23-fold Up; FDR = 0.0232; PValue = 0.00626; mean CPM = 31.80; methylmalonyl CoA mutase" ID="ID_356647302" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLAT: 1.37-fold Down; FDR = 0.034; PValue = 0.00976; mean CPM = 76.44; plasminogen activator, tissue" ID="ID_890094092" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1949660951" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SERPINA3: 1.78-fold Down; FDR = 0.0544; PValue = 0.017; mean CPM = 6.499; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3" ID="ID_451077522" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTR: 1.18-fold Down; FDR = 0.0633; PValue = 0.0203; mean CPM = 75.25; 5-methyltetrahydrofolate-homocysteine methyltransferase" ID="ID_648855063" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APOA1: 2.5-fold Down; FDR = 0.104; PValue = 0.0368; mean CPM = 0.9574; apolipoprotein A-I" ID="ID_308622318" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="F2: 1.67-fold Down; FDR = 0.132; PValue = 0.0494; mean CPM = 1.475; coagulation factor II (thrombin)" ID="ID_305937221" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GIF: 2.15-fold Down; FDR = 0.186; PValue = 0.0747; mean CPM = 0.8950; gastric intrinsic factor (vitamin B synthesis)" ID="ID_1431034556" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LRP2: 1.78-fold Down; FDR = 0.225; PValue = 0.0948; mean CPM = 1.099; low density lipoprotein receptor-related protein 2" ID="ID_105996780" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTHFR: 1.17-fold Down; FDR = 0.235; PValue = 0.1; mean CPM = 12.57; methylenetetrahydrofolate reductase (NAD(P)H)" ID="ID_1715409682" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MCEE: 1.1-fold Up; FDR = 0.587; PValue = 0.321; mean CPM = 11.90; methylmalonyl CoA epimerase" ID="ID_1735191455" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_167457494" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APOB: 1.36-fold Down; FDR = 0.723; PValue = 0.426; mean CPM = 0.9779; apolipoprotein B (including Ag(x) antigen)" ID="ID_764339695" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TCN1: 1.84-fold Down; FDR = 0.76; PValue = 0.459; mean CPM = 0.8497; transcobalamin I (vitamin B12 binding protein, R binder family)" ID="ID_711348050" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LDLR: 1.07-fold Down; FDR = 0.854; PValue = 0.567; mean CPM = 167.3; low density lipoprotein receptor" ID="ID_245336924" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HBB: 1.21-fold Up; FDR = 0.883; PValue = 0.603; mean CPM = 0.9754; hemoglobin, beta" ID="ID_1849659418" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_824672709" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_682319899" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAT1A: 1.31-fold Down; FDR = 0.903; PValue = 0.656; mean CPM = 0.8409; methionine adenosyltransferase I, alpha" ID="ID_1858081504" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="F7: 1.07-fold Down; FDR = 0.921; PValue = 0.723; mean CPM = 2.252; coagulation factor VII (serum prothrombin conversion accelerator)" ID="ID_812902947" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HBA1: 1.14-fold Up; FDR = 0.929; PValue = 0.738; mean CPM = 0.8217; hemoglobin, alpha 1" ID="ID_23906875" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLG: 1.41-fold Down; FDR = 0.937; PValue = 0.751; mean CPM = 0.8390; plasminogen" ID="ID_1579132661" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HBA2: 1.16-fold Up; FDR = 0.942; PValue = 0.76; mean CPM = 0.8111; hemoglobin, alpha 2" ID="ID_1490509954" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ALB: 1.05-fold Down; FDR = 1; PValue = 0.98; mean CPM = 0.8186; Serum albumin" ID="ID_1175586015" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000036214: 1.04-fold Down; FDR = 1; PValue = 0.988; mean CPM = 0.8094; Uncharacterized protein" ID="ID_827338929" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRP: No Change; FDR = 1; PValue = 1; mean CPM = 0.7818; Uncharacterized protein" ID="ID_1733505896" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Notch Signaling Pathway (WP61:Rev45344): FDR = 6.27e-11, PValue = 1.41e-11" ID="ID_1803748637" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_1061085868" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RBPJ: 2.84-fold Up; FDR = 1.11e-14; PValue = 1.22e-16; mean CPM = 158.0; recombination signal binding protein for immunoglobulin kappa J region" ID="ID_320020270" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOTCH3: 6.31-fold Down; FDR = 2.33e-13; PValue = 3.29e-15; mean CPM = 185.7; Notch homolog 3 (Drosophila)" ID="ID_884978319" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CIR1: 2.06-fold Up; FDR = 4.17e-13; PValue = 6.26e-15; mean CPM = 41.48; corepressor interacting with RBPJ, 1" ID="ID_1433029570" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NUMBL: 2.15-fold Down; FDR = 2.64e-11; PValue = 6.08e-13; mean CPM = 22.15; numb homolog (Drosophila)-like" ID="ID_635801062" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_465913570" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAG1: 2.62-fold Down; FDR = 3.16e-08; PValue = 1.56e-09; mean CPM = 175.2; jagged 1" ID="ID_370444187" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SAP30: 2.14-fold Up; FDR = 6.14e-08; PValue = 3.28e-09; mean CPM = 10.69; Histone deacetylase complex subunit SAP30; Uncharacterized protein" ID="ID_1940834204" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1020052592" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HEY1: 4.88-fold Down; FDR = 7.84e-07; PValue = 5.48e-08; mean CPM = 1.952; hairy/enhancer-of-split related with YRPW motif 1" ID="ID_772570364" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HES1: 2.4-fold Down; FDR = 5.84e-06; PValue = 5.13e-07; mean CPM = 75.36; hairy and enhancer of split 1, (Drosophila)" ID="ID_1112548206" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPT: 2.89-fold Down; FDR = 3.14e-05; PValue = 3.34e-06; mean CPM = 2.105; microtubule-associated protein tau" ID="ID_329217112" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADAM17: 1.32-fold Up; FDR = 0.00063; PValue = 9.95e-05; mean CPM = 118.8; ADAM metallopeptidase domain 17" ID="ID_1154284211" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GATA3: 2.81-fold Up; FDR = 0.000734; PValue = 0.000119; mean CPM = 2.229; GATA binding protein 3" ID="ID_1389935169" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APH1B: 1.39-fold Up; FDR = 0.000776; PValue = 0.000126; mean CPM = 17.84; anterior pharynx defective 1 homolog B (C. elegans)" ID="ID_1656521030" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000039874: 1.3-fold Up; FDR = 0.001; PValue = 0.000168; mean CPM = 80.13; Uncharacterized protein" ID="ID_140126623" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSENEN: 1.31-fold Up; FDR = 0.00118; PValue = 0.000203; mean CPM = 76.54; presenilin enhancer 2 homolog (C. elegans)" ID="ID_1874934742" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOTCH1: 1.44-fold Down; FDR = 0.0032; PValue = 0.000634; mean CPM = 32.99; Notch homolog 1, translocation-associated (Drosophila)" ID="ID_577951665" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CUL1: 1.24-fold Up; FDR = 0.0104; PValue = 0.00247; mean CPM = 106.1; cullin 1" ID="ID_493407047" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC1: 1.25-fold Up; FDR = 0.0159; PValue = 0.00403; mean CPM = 27.51; histone deacetylase 1" ID="ID_985301604" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_410813649" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAML1: 1.23-fold Down; FDR = 0.0266; PValue = 0.00733; mean CPM = 45.38; mastermind-like 1 (Drosophila)" ID="ID_1593264093" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCSTN: 1.21-fold Up; FDR = 0.0284; PValue = 0.0079; mean CPM = 205.1; nicastrin" ID="ID_1131889288" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_865315840" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DTX1: 2.82-fold Down; FDR = 0.0473; PValue = 0.0144; mean CPM = 0.9361; deltex homolog 1 (Drosophila)" ID="ID_1532068617" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPEN: 1.18-fold Down; FDR = 0.0585; PValue = 0.0185; mean CPM = 128.1; spen family transcriptional repressor" ID="ID_1131162437" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_755854785" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DLL1: 1.66-fold Up; FDR = 0.0898; PValue = 0.0308; mean CPM = 2.702; delta-like 1 (Drosophila)" ID="ID_448446190" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FHL1: 1.23-fold Up; FDR = 0.0938; PValue = 0.0325; mean CPM = 85.43; four and a half LIM domains 1" ID="ID_1641369675" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC2: 1.15-fold Up; FDR = 0.115; PValue = 0.0414; mean CPM = 93.64; histone deacetylase 2" ID="ID_988292814" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND1: 1.17-fold Up; FDR = 0.121; PValue = 0.0443; mean CPM = 867.3; cyclin D1" ID="ID_5809928" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_199164" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RING1: 1.14-fold Down; FDR = 0.155; PValue = 0.0598; mean CPM = 54.55; ring finger protein 1" ID="ID_238062000" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SKP1: 1.14-fold Up; FDR = 0.176; PValue = 0.07; mean CPM = 88.20; S-phase kinase-associated protein 1" ID="ID_785469922" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FBXW7: 1.17-fold Down; FDR = 0.181; PValue = 0.0727; mean CPM = 33.48; F-box and WD repeat domain containing 7" ID="ID_262409295" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DLL4: 1.82-fold Down; FDR = 0.2; PValue = 0.0824; mean CPM = 1.928; delta-like 4 (Drosophila)" ID="ID_488313402" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HES6: 1.71-fold Down; FDR = 0.214; PValue = 0.0895; mean CPM = 1.226; hairy and enhancer of split 6 (Drosophila)" ID="ID_1665381795" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000041158: 1.15-fold Up; FDR = 0.216; PValue = 0.0905; mean CPM = 24.28; Uncharacterized protein" ID="ID_1329702068" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSEN1: 1.12-fold Up; FDR = 0.233; PValue = 0.0992; mean CPM = 62.12; presenilin 1" ID="ID_1208139136" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1A: 1.16-fold Down; FDR = 0.28; PValue = 0.124; mean CPM = 363.2; Cyclin-dependent kinase inhibitor 1; Uncharacterized protein" ID="ID_869031950" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EP300: 1.11-fold Up; FDR = 0.312; PValue = 0.142; mean CPM = 162.8; E1A binding protein p300" ID="ID_547864720" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSEN2: 1.11-fold Down; FDR = 0.445; PValue = 0.222; mean CPM = 23.33; Uncharacterized protein" ID="ID_1207224481" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAG2: 1.26-fold Down; FDR = 0.511; PValue = 0.266; mean CPM = 3.134; Delta-like protein" ID="ID_443140965" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HEY2: 1.61-fold Down; FDR = 0.514; PValue = 0.268; mean CPM = 0.9173; hairy/enhancer-of-split related with YRPW motif 2" ID="ID_1076976170" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOTCH2: 1.09-fold Down; FDR = 0.514; PValue = 0.268; mean CPM = 795.0; Notch homolog 2 (Drosophila)" ID="ID_1665092786" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTCRA: 1.99-fold Down; FDR = 0.68; PValue = 0.391; mean CPM = 0.8703; pre T-cell antigen receptor alpha" ID="ID_1409358084" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DLL3: 1.09-fold Down; FDR = 0.808; PValue = 0.504; mean CPM = 5.871; delta-like 3 (Drosophila)" ID="ID_223174718" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APH1A: 1.05-fold Up; FDR = 0.828; PValue = 0.529; mean CPM = 85.70; anterior pharynx defective 1 homolog A (C. elegans)" ID="ID_1752060586" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NUMB: 1.03-fold Up; FDR = 0.909; PValue = 0.687; mean CPM = 60.96; numb homolog (Drosophila)" ID="ID_1025497852" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAGEA1: No Change; FDR = 1; PValue = 1; mean CPM = 0.7818; melanoma antigen family A, 1 (directs expression of antigen MZ2-E)" ID="ID_879187372" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Epithelium TarBase (WP2002:Rev45243): FDR = 8.3e-11, PValue = 1.9e-11" ID="ID_633906748" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="ADAR: 2.84-fold Up; FDR = 8.44e-21; PValue = 2.66e-23; mean CPM = 291.8; adenosine deaminase, RNA-specific" ID="ID_1063554534" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BACE1: 2.47-fold Down; FDR = 5.34e-16; PValue = 4.61e-18; mean CPM = 93.58; beta-site APP-cleaving enzyme 1" ID="ID_1096568662" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SDCBP: 2.11-fold Up; FDR = 2.04e-15; PValue = 1.89e-17; mean CPM = 226.9; Syntenin-1 isoform 1; Uncharacterized protein" ID="ID_247508521" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL3A1: 20.5-fold Down; FDR = 5.71e-15; PValue = 5.82e-17; mean CPM = 5961; collagen, type III, alpha 1" ID="ID_481611584" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL1A1: 21.5-fold Down; FDR = 1.13e-13; PValue = 1.5e-15; mean CPM = 15389; collagen, type I, alpha 1" ID="ID_1905760394" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFAIP2: 3.61-fold Up; FDR = 1.42e-13; PValue = 1.95e-15; mean CPM = 54.70; tumor necrosis factor, alpha-induced protein 2" ID="ID_1344870640" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000036781: 2.4-fold Down; FDR = 1.7e-13; PValue = 2.35e-15; mean CPM = 342.5; Uncharacterized protein" ID="ID_5242856" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHOB: 2.87-fold Down; FDR = 2.74e-13; PValue = 3.96e-15; mean CPM = 84.32; ras homolog gene family, member B" ID="ID_521147257" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MET: 2.57-fold Up; FDR = 3.56e-13; PValue = 5.22e-15; mean CPM = 242.4; Macaca mulatta met proto-oncogene (hepatocyte growth factor receptor) (MET), mRNA." ID="ID_1755602850" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF2R: 2.41-fold Down; FDR = 4.2e-13; PValue = 6.32e-15; mean CPM = 245.2; insulin-like growth factor 2 receptor" ID="ID_1511921763" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDLIM7: 2.02-fold Down; FDR = 4.87e-13; PValue = 7.39e-15; mean CPM = 284.3; PDZ and LIM domain 7 (enigma)" ID="ID_1720773962" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMC1: 2.28-fold Down; FDR = 6.46e-13; PValue = 1.01e-14; mean CPM = 812.1; laminin, gamma 1 (formerly LAMB2)" ID="ID_1880491522" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SNX6: 1.88-fold Up; FDR = 2.14e-12; PValue = 3.75e-14; mean CPM = 91.06; sorting nexin 6" ID="ID_245084506" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="UNC93B1: 2.26-fold Up; FDR = 3.4e-12; PValue = 6.25e-14; mean CPM = 28.55; unc-93 homolog B1 (C. elegans)" ID="ID_414269885" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATG9A: 1.77-fold Down; FDR = 1.17e-11; PValue = 2.46e-13; mean CPM = 69.44; ATG9 autophagy related 9 homolog A (S. cerevisiae)" ID="ID_1960481993" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BRPF3: 2-fold Down; FDR = 4.77e-11; PValue = 1.17e-12; mean CPM = 36.05; bromodomain and PHD finger containing, 3" ID="ID_1278643393" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MRC2: 2.12-fold Down; FDR = 1.81e-10; PValue = 5.07e-12; mean CPM = 772.3; mannose receptor, C type 2" ID="ID_1405671186" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AC137834.2: 2.11-fold Down; FDR = 3.29e-10; PValue = 9.87e-12; mean CPM = 1681; Prolow-density lipoprotein receptor-related protein 1 Precursor (LRP-1)(Alpha-2-macroglobulin receptor)(A2MR)(Apolipoprotein E receptor)(APOER)(CD91 antigen) [Contains Low-density lipoprotein receptor-related protein 1 85 kDa subunit(LRP-85);Low-den /.../ipoprotein receptor-related protein 1 515 kDa subunit(LRP-515);Low-density lipoprotein receptor-related protein 1 intracellular domain(LRPICD)]" ID="ID_1556399611" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="P4HA2: 2.27-fold Down; FDR = 3.92e-10; PValue = 1.2e-11; mean CPM = 511.5; prolyl 4-hydroxylase, alpha polypeptide II" ID="ID_1361188088" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPRF: 2.51-fold Down; FDR = 5.51e-10; PValue = 1.77e-11; mean CPM = 184.0; protein tyrosine phosphatase, receptor type, F" ID="ID_160431959" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGFR: 1.84-fold Up; FDR = 6.71e-09; PValue = 2.77e-10; mean CPM = 68.58; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)" ID="ID_568304427" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1B: 1.64-fold Up; FDR = 1.22e-08; PValue = 5.39e-10; mean CPM = 32.96; Cyclin-dependent kinase inhibitor 1B; Uncharacterized protein" ID="ID_1201134625" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TPM4: 1.8-fold Down; FDR = 1.34e-08; PValue = 5.96e-10; mean CPM = 1400; tropomyosin 4" ID="ID_1925932360" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SCYL1: 1.55-fold Down; FDR = 1.88e-08; PValue = 8.75e-10; mean CPM = 136.7; SCY1-like 1 (S. cerevisiae)" ID="ID_1961504946" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDCP1: 2.18-fold Up; FDR = 2.98e-08; PValue = 1.46e-09; mean CPM = 134.3; CUB domain containing protein 1" ID="ID_23971540" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EZH2: 2.05-fold Up; FDR = 4.94e-08; PValue = 2.57e-09; mean CPM = 24.23; enhancer of zeste homolog 2 (Drosophila)" ID="ID_1181296902" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RB1: 1.65-fold Up; FDR = 6.01e-08; PValue = 3.2e-09; mean CPM = 59.24; retinoblastoma 1" ID="ID_90232088" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="YIF1B: 1.68-fold Down; FDR = 1.19e-07; PValue = 6.76e-09; mean CPM = 70.16; Yip1 interacting factor homolog B (S. cerevisiae)" ID="ID_1387851386" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IDH1: 1.87-fold Up; FDR = 1.39e-07; PValue = 8.02e-09; mean CPM = 56.62; isocitrate dehydrogenase 1 (NADP+), soluble" ID="ID_295061185" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PGRMC1: 1.49-fold Up; FDR = 2.86e-07; PValue = 1.79e-08; mean CPM = 67.51; progesterone receptor membrane component 1" ID="ID_13125802" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PODXL: 4.78-fold Up; FDR = 5.61e-07; PValue = 3.77e-08; mean CPM = 2.315; podocalyxin-like" ID="ID_473631079" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AARSD1: 1.59-fold Down; FDR = 7.9e-07; PValue = 5.53e-08; mean CPM = 19.40; alanyl-tRNA synthetase domain containing 1" ID="ID_128512470" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACP2: 1.49-fold Up; FDR = 9.22e-07; PValue = 6.59e-08; mean CPM = 58.72; acid phosphatase 2, lysosomal" ID="ID_312573224" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GAK: 1.46-fold Down; FDR = 9.29e-07; PValue = 6.67e-08; mean CPM = 90.22; cyclin G associated kinase" ID="ID_1334605071" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CORO1C: 1.47-fold Down; FDR = 1.18e-06; PValue = 8.66e-08; mean CPM = 186.3; Coronin" ID="ID_1348854692" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000002068: 1.63-fold Down; FDR = 2.68e-06; PValue = 2.15e-07; mean CPM = 20.88" ID="ID_1611584216" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BACH1: 1.69-fold Up; FDR = 3.53e-06; PValue = 2.94e-07; mean CPM = 503.5; BTB and CNC homology 1, basic leucine zipper transcription factor 1" ID="ID_1352923621" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARHGDIA: 1.49-fold Down; FDR = 3.61e-06; PValue = 3.01e-07; mean CPM = 257.2; Rho GDP dissociation inhibitor (GDI) alpha" ID="ID_781746354" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFRD1: 1.57-fold Up; FDR = 5.76e-06; PValue = 5.05e-07; mean CPM = 71.59; interferon-related developmental regulator 1" ID="ID_382830726" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HES1: 2.4-fold Down; FDR = 5.84e-06; PValue = 5.13e-07; mean CPM = 75.36; hairy and enhancer of split 1, (Drosophila)" ID="ID_1204403877" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TUBA1A: 1.66-fold Down; FDR = 7.24e-06; PValue = 6.58e-07; mean CPM = 305.6; tubulin, alpha 1a" ID="ID_83858879" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMED3: 1.49-fold Down; FDR = 7.47e-06; PValue = 6.8e-07; mean CPM = 282.0; transmembrane emp24 protein transport domain containing 3" ID="ID_1332679242" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPIB: 1.45-fold Down; FDR = 8.64e-06; PValue = 8.03e-07; mean CPM = 806.4; peptidylprolyl isomerase B (cyclophilin B)" ID="ID_1734755748" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMC2: 2.28-fold Down; FDR = 9.83e-06; PValue = 9.24e-07; mean CPM = 16.99; laminin, gamma 2" ID="ID_589230437" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PHLDB2: 1.45-fold Down; FDR = 1.07e-05; PValue = 1.01e-06; mean CPM = 341.6; pleckstrin homology-like domain, family B, member 2" ID="ID_727773126" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GAS2L1: 1.5-fold Down; FDR = 1.44e-05; PValue = 1.41e-06; mean CPM = 29.74; growth arrest-specific 2 like 1" ID="ID_16711854" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT5A: 1.65-fold Down; FDR = 2.5e-05; PValue = 2.59e-06; mean CPM = 136.4; wingless-type MMTV integration site family, member 5A" ID="ID_1069397118" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYO1E: 1.54-fold Down; FDR = 3.16e-05; PValue = 3.37e-06; mean CPM = 330.9; myosin IE" ID="ID_369968772" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VTI1B: 1.4-fold Up; FDR = 3.18e-05; PValue = 3.4e-06; mean CPM = 42.89; vesicle transport through interaction with t-SNAREs homolog 1B (yeast)" ID="ID_399358236" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLK1: 2.25-fold Down; FDR = 3.23e-05; PValue = 3.46e-06; mean CPM = 27.29; polo-like kinase 1 (Drosophila)" ID="ID_1226259839" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNG1: 1.38-fold Up; FDR = 6.77e-05; PValue = 8.01e-06; mean CPM = 149.9; cyclin G1" ID="ID_612476042" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HMOX1: 1.94-fold Up; FDR = 7.83e-05; PValue = 9.42e-06; mean CPM = 15.01; heme oxygenase (decycling) 1" ID="ID_172813471" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GJA1: 1.71-fold Up; FDR = 0.000117; PValue = 1.47e-05; mean CPM = 2600; gap junction protein, alpha 1, 43kDa" ID="ID_1430592057" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMEM109: 1.4-fold Down; FDR = 0.000118; PValue = 1.49e-05; mean CPM = 78.40; transmembrane protein 109" ID="ID_1438502315" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSRP1: 1.59-fold Down; FDR = 0.000168; PValue = 2.23e-05; mean CPM = 630.6; cysteine and glycine-rich protein 1" ID="ID_1070541848" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MRM1: 1.59-fold Up; FDR = 0.000177; PValue = 2.37e-05; mean CPM = 8.176; mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)" ID="ID_1807281147" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARF4: 1.35-fold Down; FDR = 0.000178; PValue = 2.38e-05; mean CPM = 179.9; ADP-ribosylation factor 4" ID="ID_927144617" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTRR: 1.38-fold Up; FDR = 0.000187; PValue = 2.52e-05; mean CPM = 32.85; 5-methyltetrahydrofolate-homocysteine methyltransferase reductase" ID="ID_1594063255" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHD1: 1.35-fold Up; FDR = 0.000225; PValue = 3.11e-05; mean CPM = 82.41; chromodomain helicase DNA binding protein 1" ID="ID_1023251750" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP6V0E1: 1.38-fold Up; FDR = 0.000282; PValue = 4.02e-05; mean CPM = 138.5; ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1" ID="ID_429204780" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDLIM5: 1.52-fold Down; FDR = 0.000341; PValue = 4.98e-05; mean CPM = 521.2; PDZ and LIM domain 5" ID="ID_1548995595" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC25A1: 1.35-fold Down; FDR = 0.000363; PValue = 5.35e-05; mean CPM = 37.11; solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1" ID="ID_1512630521" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HOXD8: 2.21-fold Up; FDR = 0.000453; PValue = 6.86e-05; mean CPM = 2.741; homeobox D8" ID="ID_526980406" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FNDC3A: 1.33-fold Up; FDR = 0.000492; PValue = 7.51e-05; mean CPM = 145.6; fibronectin type III domain containing 3A" ID="ID_228409728" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMC1A: 1.33-fold Down; FDR = 0.000521; PValue = 8.03e-05; mean CPM = 42.68; structural maintenance of chromosomes 1A" ID="ID_1227285301" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NRP1: 1.48-fold Up; FDR = 0.000563; PValue = 8.76e-05; mean CPM = 54.61; neuropilin 1" ID="ID_1138975315" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD3: 1.38-fold Up; FDR = 0.000573; PValue = 8.94e-05; mean CPM = 114.9; SMAD family member 3" ID="ID_1983377466" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AMIGO2: 2.39-fold Down; FDR = 0.000639; PValue = 0.000101; mean CPM = 22.90; adhesion molecule with Ig-like domain 2" ID="ID_393347084" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FNDC3B: 1.32-fold Down; FDR = 0.000691; PValue = 0.000111; mean CPM = 260.1; fibronectin type III domain containing 3B" ID="ID_445153653" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYR61: 1.38-fold Down; FDR = 0.000719; PValue = 0.000116; mean CPM = 1035; cysteine-rich, angiogenic inducer, 61" ID="ID_821282829" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCKDHB: 1.49-fold Down; FDR = 0.000761; PValue = 0.000123; mean CPM = 9.393; branched chain keto acid dehydrogenase E1, beta polypeptide" ID="ID_1946261675" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033454: 1.33-fold Down; FDR = 0.00107; PValue = 0.000183; mean CPM = 1120; Pyruvate kinase" ID="ID_1110051153" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C1QBP: 1.36-fold Up; FDR = 0.00107; PValue = 0.000183; mean CPM = 83.61; complement component 1, q subcomponent binding protein" ID="ID_1861095410" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DOCK5: 1.3-fold Down; FDR = 0.00111; PValue = 0.00019; mean CPM = 133.4; dedicator of cytokinesis 5" ID="ID_110234925" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NT5E: 1.42-fold Up; FDR = 0.00145; PValue = 0.000258; mean CPM = 199.3; 5'-nucleotidase, ecto (CD73)" ID="ID_1726381752" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WDFY1: 1.3-fold Up; FDR = 0.00145; PValue = 0.000258; mean CPM = 69.31; WD repeat and FYVE domain containing 1" ID="ID_951325578" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMEM189-UBE2V1: 1.29-fold Down; FDR = 0.00163; PValue = 0.000294; mean CPM = 47.08; TMEM189-UBE2V1 readthrough" ID="ID_1897017138" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RRP8: 1.41-fold Down; FDR = 0.00182; PValue = 0.000335; mean CPM = 12.14; ribosomal RNA processing 8, methyltransferase, homolog (yeast)" ID="ID_534313909" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAD23B: 1.34-fold Up; FDR = 0.00235; PValue = 0.000445; mean CPM = 210.1; RAD23 homolog B (S. cerevisiae)" ID="ID_1654677660" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DHX15: 1.28-fold Up; FDR = 0.00298; PValue = 0.000582; mean CPM = 152.3; DEAH (Asp-Glu-Ala-His) box polypeptide 15" ID="ID_42523829" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRPEL2: 1.39-fold Up; FDR = 0.00298; PValue = 0.000584; mean CPM = 21.71; GrpE-like 2, mitochondrial (E. coli)" ID="ID_906086041" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOTCH1: 1.44-fold Down; FDR = 0.0032; PValue = 0.000634; mean CPM = 32.99; Notch homolog 1, translocation-associated (Drosophila)" ID="ID_92147208" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTHFD2: 1.37-fold Up; FDR = 0.00326; PValue = 0.000646; mean CPM = 158.6; methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase" ID="ID_160908922" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="UTP15: 1.36-fold Up; FDR = 0.00331; PValue = 0.000658; mean CPM = 16.13; UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)" ID="ID_1332023486" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSAT1: 1.79-fold Up; FDR = 0.00355; PValue = 0.000715; mean CPM = 220.2; Uncharacterized protein" ID="ID_880574811" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRPF40A: 1.27-fold Up; FDR = 0.00357; PValue = 0.00072; mean CPM = 164.5; PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)" ID="ID_272281792" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB4: 1.66-fold Down; FDR = 0.00369; PValue = 0.000748; mean CPM = 5.291; integrin, beta 4" ID="ID_1453750172" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STX7: 1.29-fold Up; FDR = 0.00375; PValue = 0.000762; mean CPM = 40.57; Syntaxin-7; Uncharacterized protein" ID="ID_1562064433" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SYPL1: 1.29-fold Up; FDR = 0.00402; PValue = 0.000826; mean CPM = 28.95; synaptophysin-like 1" ID="ID_124401477" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000023633: 2.4-fold Up; FDR = 0.00403; PValue = 0.00083; mean CPM = 1.597; Uncharacterized protein" ID="ID_911199298" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NARS: 1.28-fold Up; FDR = 0.00405; PValue = 0.000834; mean CPM = 348.3; asparaginyl-tRNA synthetase" ID="ID_1545901948" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TDG: 1.3-fold Down; FDR = 0.00422; PValue = 0.000874; mean CPM = 24.07; thymine-DNA glycosylase" ID="ID_987758232" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARID1A: 1.27-fold Down; FDR = 0.00443; PValue = 0.000925; mean CPM = 100.8; AT rich interactive domain 1A (SWI-like)" ID="ID_340720706" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC25A24: 1.27-fold Up; FDR = 0.00467; PValue = 0.000982; mean CPM = 71.95; solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24" ID="ID_300041888" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SEC62: 1.26-fold Up; FDR = 0.00511; PValue = 0.00109; mean CPM = 81.14; SEC62 homolog (S. cerevisiae)" ID="ID_428786470" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FAR1: 1.28-fold Up; FDR = 0.00521; PValue = 0.00111; mean CPM = 33.54; fatty acyl CoA reductase 1" ID="ID_1190736959" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC4: 1.38-fold Down; FDR = 0.00526; PValue = 0.00112; mean CPM = 48.60; histone deacetylase 4" ID="ID_228454746" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VEZT: 1.25-fold Up; FDR = 0.0069; PValue = 0.00153; mean CPM = 74.30; vezatin, adherens junctions transmembrane protein" ID="ID_1860037743" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC1A4: 1.4-fold Down; FDR = 0.00754; PValue = 0.0017; mean CPM = 83.85; solute carrier family 1 (glutamate/neutral amino acid transporter), member 4" ID="ID_1238207545" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IQGAP3: 1.55-fold Down; FDR = 0.0122; PValue = 0.00296; mean CPM = 43.66; IQ motif containing GTPase activating protein 3" ID="ID_854477952" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHAF1A: 1.42-fold Down; FDR = 0.0138; PValue = 0.00339; mean CPM = 19.62; Uncharacterized protein" ID="ID_1873204937" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRIP13: 1.56-fold Down; FDR = 0.0144; PValue = 0.00359; mean CPM = 13.12; Uncharacterized protein" ID="ID_693633496" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSD17B12: 1.26-fold Up; FDR = 0.0145; PValue = 0.0036; mean CPM = 51.46; hydroxysteroid (17-beta) dehydrogenase 12" ID="ID_576756761" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RTN4: 1.23-fold Up; FDR = 0.0145; PValue = 0.0036; mean CPM = 165.8; Reticulon" ID="ID_671901114" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARFIP2: 1.23-fold Down; FDR = 0.0147; PValue = 0.00366; mean CPM = 52.18; ADP-ribosylation factor interacting protein 2" ID="ID_1393070795" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CPNE8: 1.43-fold Up; FDR = 0.0153; PValue = 0.00384; mean CPM = 8.182; copine VIII" ID="ID_1187924131" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SNX19: 1.22-fold Down; FDR = 0.0154; PValue = 0.00388; mean CPM = 67.24; sorting nexin 19" ID="ID_28258233" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HBXIP: 1.24-fold Up; FDR = 0.0155; PValue = 0.00392; mean CPM = 74.39; Uncharacterized protein" ID="ID_31738789" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GOLGA7: 1.25-fold Up; FDR = 0.0161; PValue = 0.00408; mean CPM = 28.83; golgin A7" ID="ID_1001608276" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LMNB2: 1.32-fold Down; FDR = 0.0162; PValue = 0.00412; mean CPM = 72.73; lamin B2" ID="ID_948464282" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADIPOR2: 1.46-fold Down; FDR = 0.0179; PValue = 0.00461; mean CPM = 21.90; adiponectin receptor 2" ID="ID_999637314" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SYNE1: 1.26-fold Up; FDR = 0.0191; PValue = 0.005; mean CPM = 384.7; spectrin repeat containing, nuclear envelope 1" ID="ID_1137969414" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYP1B1: 1.38-fold Down; FDR = 0.0201; PValue = 0.00528; mean CPM = 273.1; cytochrome P450, family 1, subfamily B, polypeptide 1" ID="ID_713248310" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GALNT7: 1.31-fold Up; FDR = 0.0218; PValue = 0.0058; mean CPM = 12.18; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)" ID="ID_558607687" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FSTL1: 1.23-fold Down; FDR = 0.0219; PValue = 0.00585; mean CPM = 1004; microRNA 198" ID="ID_236279592" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SYNE2: 1.42-fold Up; FDR = 0.0223; PValue = 0.00597; mean CPM = 76.79; spectrin repeat containing, nuclear envelope 2" ID="ID_351238803" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSDE1: 1.22-fold Up; FDR = 0.0231; PValue = 0.0062; mean CPM = 461.0; Uncharacterized protein" ID="ID_180315775" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BRI3BP: 1.53-fold Down; FDR = 0.0255; PValue = 0.00698; mean CPM = 5.012; BRI3 binding protein" ID="ID_116535815" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TXN2: 1.21-fold Down; FDR = 0.026; PValue = 0.00713; mean CPM = 40.77; thioredoxin 2" ID="ID_782842494" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AURKB: 1.68-fold Down; FDR = 0.0261; PValue = 0.00715; mean CPM = 10.71; aurora kinase B" ID="ID_1753211707" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PNP: 1.54-fold Up; FDR = 0.0261; PValue = 0.00717; mean CPM = 3.794; Purine nucleoside phosphorylase" ID="ID_1514410034" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDIPT: 1.21-fold Down; FDR = 0.0297; PValue = 0.00831; mean CPM = 71.76; CDP-diacylglycerol--inositol 3-phosphatidyltransferase" ID="ID_1630441598" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KCNJ2: 1.99-fold Up; FDR = 0.0298; PValue = 0.00835; mean CPM = 4.009; potassium inwardly-rectifying channel, subfamily J, member 2" ID="ID_877624295" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MCL1: 1.2-fold Up; FDR = 0.0335; PValue = 0.00961; mean CPM = 193.8; myeloid cell leukemia sequence 1 (BCL2-related)" ID="ID_953591164" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAND1: 1.2-fold Up; FDR = 0.0393; PValue = 0.0116; mean CPM = 164.5; cullin-associated and neddylation-dissociated 1" ID="ID_661830312" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NUCB1: 1.21-fold Down; FDR = 0.0393; PValue = 0.0116; mean CPM = 323.6; nucleobindin 1" ID="ID_118585477" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KRAS: 1.35-fold Down; FDR = 0.0401; PValue = 0.0119; mean CPM = 13.10; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog" ID="ID_47325698" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FADS1: 1.2-fold Down; FDR = 0.0424; PValue = 0.0126; mean CPM = 133.1; fatty acid desaturase 1" ID="ID_522053569" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="E2F1: 1.44-fold Down; FDR = 0.0425; PValue = 0.0127; mean CPM = 8.857; E2F transcription factor 1" ID="ID_277736172" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNA13: 1.25-fold Up; FDR = 0.0428; PValue = 0.0128; mean CPM = 15.41; guanine nucleotide binding protein (G protein), alpha 13" ID="ID_178909875" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NXN: 1.19-fold Down; FDR = 0.0457; PValue = 0.0138; mean CPM = 70.27; nucleoredoxin" ID="ID_397349000" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYP51A1: 1.2-fold Down; FDR = 0.0512; PValue = 0.0158; mean CPM = 34.30; cytochrome P450, family 51, subfamily A, polypeptide 1" ID="ID_1159043159" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTX1: 1.19-fold Down; FDR = 0.0589; PValue = 0.0187; mean CPM = 30.48; metaxin 1" ID="ID_1336969542" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFBR2: 1.19-fold Up; FDR = 0.0643; PValue = 0.0208; mean CPM = 350.8; transforming growth factor, beta receptor II (70/80kDa)" ID="ID_873367201" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MRPS33: 1.21-fold Up; FDR = 0.0695; PValue = 0.0228; mean CPM = 20.91; mitochondrial ribosomal protein S33" ID="ID_1845202367" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC25A22: 1.22-fold Up; FDR = 0.0697; PValue = 0.0228; mean CPM = 27.74; solute carrier family 25 (mitochondrial carrier: glutamate), member 22" ID="ID_1830575890" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD164: 1.17-fold Up; FDR = 0.0745; PValue = 0.0247; mean CPM = 58.11; CD164 molecule, sialomucin" ID="ID_1154325675" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DNAJB1: 1.18-fold Up; FDR = 0.0756; PValue = 0.0252; mean CPM = 33.66; DnaJ (Hsp40) homolog, subfamily B, member 1" ID="ID_579051566" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EHMT1: 1.17-fold Down; FDR = 0.0774; PValue = 0.0259; mean CPM = 58.20; euchromatic histone-lysine N-methyltransferase 1" ID="ID_1258479983" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K8: 1.35-fold Down; FDR = 0.0831; PValue = 0.0281; mean CPM = 8.912; mitogen-activated protein kinase kinase kinase 8" ID="ID_452784462" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SERP1: 1.17-fold Down; FDR = 0.0832; PValue = 0.0282; mean CPM = 113.3; Ribosome-associated membrane protein RAMP4-2; Stress-associated endoplasmic reticulum protein 1; Uncharacterized protein" ID="ID_1565519558" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPIF: 1.22-fold Down; FDR = 0.0887; PValue = 0.0304; mean CPM = 22.64; peptidylprolyl isomerase F" ID="ID_1475747272" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="UBE2S: 1.17-fold Down; FDR = 0.0945; PValue = 0.0328; mean CPM = 65.24; ubiquitin-conjugating enzyme E2S" ID="ID_684078265" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ANP32B: 1.23-fold Up; FDR = 0.1; PValue = 0.0352; mean CPM = 12.72; acidic (leucine-rich) nuclear phosphoprotein 32 family, member B" ID="ID_1901048598" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLDN1: 1.57-fold Up; FDR = 0.1; PValue = 0.0352; mean CPM = 7.527; claudin 1" ID="ID_1572229135" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PNP: 1.29-fold Up; FDR = 0.101; PValue = 0.0357; mean CPM = 44.02; purine nucleoside phosphorylase" ID="ID_485741617" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FBXW11: 1.16-fold Up; FDR = 0.106; PValue = 0.0378; mean CPM = 64.90; F-box and WD repeat domain containing 11" ID="ID_1806081438" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND1: 1.17-fold Up; FDR = 0.121; PValue = 0.0443; mean CPM = 867.3; cyclin D1" ID="ID_496102621" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HOXC8: 1.2-fold Down; FDR = 0.122; PValue = 0.0444; mean CPM = 13.73; homeobox C8" ID="ID_1622375998" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAI2: 1.15-fold Down; FDR = 0.134; PValue = 0.0501; mean CPM = 356.3; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2" ID="ID_395043137" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FAM96A: 1.3-fold Up; FDR = 0.152; PValue = 0.0583; mean CPM = 5.371; family with sequence similarity 96, member A" ID="ID_171248399" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CEP72: 1.39-fold Down; FDR = 0.163; PValue = 0.0636; mean CPM = 2.653; centrosomal protein 72kDa" ID="ID_331685943" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYLIP: 1.27-fold Down; FDR = 0.163; PValue = 0.0637; mean CPM = 13.73; myosin regulatory light chain interacting protein" ID="ID_414639635" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZNF622: 1.14-fold Up; FDR = 0.166; PValue = 0.0651; mean CPM = 40.23; zinc finger protein 622" ID="ID_569486568" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SERPINE2: 1.3-fold Up; FDR = 0.169; PValue = 0.0664; mean CPM = 5738; Glia-derived nexin isoform c; Uncharacterized protein" ID="ID_993511105" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAGT1: 1.14-fold Down; FDR = 0.17; PValue = 0.0674; mean CPM = 86.91; magnesium transporter 1" ID="ID_1936670810" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC12A2: 1.16-fold Down; FDR = 0.179; PValue = 0.0714; mean CPM = 21.23; solute carrier family 12 (sodium/potassium/chloride transporters), member 2" ID="ID_34576669" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTPN: 1.13-fold Up; FDR = 0.185; PValue = 0.0746; mean CPM = 120.1; leucine zipper protein 6" ID="ID_744070796" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHEB: 1.13-fold Up; FDR = 0.193; PValue = 0.0785; mean CPM = 118.9; Ras homolog enriched in brain" ID="ID_671546815" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PHC2: 1.13-fold Up; FDR = 0.194; PValue = 0.0789; mean CPM = 182.9; polyhomeotic homolog 2 (Drosophila)" ID="ID_1252607183" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WDR82: 1.13-fold Up; FDR = 0.194; PValue = 0.0791; mean CPM = 43.33; WD repeat domain 82" ID="ID_1909858084" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHMP2A: 1.13-fold Up; FDR = 0.197; PValue = 0.0805; mean CPM = 122.1; chromatin modifying protein 2A" ID="ID_1829769468" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACAA2: 1.13-fold Up; FDR = 0.198; PValue = 0.0811; mean CPM = 42.36; acetyl-CoA acyltransferase 2" ID="ID_1405825923" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="POLD2: 1.15-fold Down; FDR = 0.21; PValue = 0.0872; mean CPM = 59.57; polymerase (DNA directed), delta 2, regulatory subunit 50kDa" ID="ID_559212457" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="YWHAQ: 1.13-fold Up; FDR = 0.216; PValue = 0.0903; mean CPM = 187.3; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide" ID="ID_1893432976" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAI14: 1.13-fold Down; FDR = 0.233; PValue = 0.0989; mean CPM = 323.5; retinoic acid induced 14" ID="ID_1694832804" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAB6A: 1.12-fold Up; FDR = 0.234; PValue = 0.0994; mean CPM = 78.40; RAB6A, member RAS oncogene family" ID="ID_105820959" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SNAP29: 1.13-fold Up; FDR = 0.239; PValue = 0.102; mean CPM = 28.83; synaptosomal-associated protein, 29kDa" ID="ID_1311171032" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAB34: 1.12-fold Down; FDR = 0.24; PValue = 0.103; mean CPM = 96.35; RAB34, member RAS oncogene family" ID="ID_529962130" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RDH10: 1.22-fold Up; FDR = 0.27; PValue = 0.119; mean CPM = 17.06; retinol dehydrogenase 10 (all-trans)" ID="ID_1682757924" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LTN1: 1.11-fold Up; FDR = 0.29; PValue = 0.13; mean CPM = 87.31; listerin E3 ubiquitin protein ligase 1" ID="ID_1656368632" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DCAF7: 1.12-fold Down; FDR = 0.301; PValue = 0.136; mean CPM = 29.90; DDB1 and CUL4 associated factor 7" ID="ID_1818376045" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GEMIN7: 1.18-fold Down; FDR = 0.301; PValue = 0.136; mean CPM = 8.388; gem (nuclear organelle) associated protein 7" ID="ID_1011127757" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK6: 1.18-fold Down; FDR = 0.301; PValue = 0.136; mean CPM = 26.51; cyclin-dependent kinase 6" ID="ID_471322953" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMED2: 1.11-fold Down; FDR = 0.312; PValue = 0.142; mean CPM = 201.8; transmembrane emp24 domain trafficking protein 2" ID="ID_1343169529" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TH1L: 1.11-fold Down; FDR = 0.315; PValue = 0.144; mean CPM = 56.09; TH1-like (Drosophila)" ID="ID_1427063320" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC4A10: 1.9-fold Down; FDR = 0.326; PValue = 0.15; mean CPM = 0.8928; Sodium-driven chloride bicarbonate exchanger isoform 2; Uncharacterized protein" ID="ID_378201446" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DMTF1: 1.11-fold Up; FDR = 0.331; PValue = 0.153; mean CPM = 32.97; cyclin D binding myb-like transcription factor 1" ID="ID_821355221" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAPG: 1.11-fold Up; FDR = 0.334; PValue = 0.155; mean CPM = 333.3; capping protein (actin filament), gelsolin-like" ID="ID_293619743" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF10B: 1.13-fold Down; FDR = 0.343; PValue = 0.16; mean CPM = 40.59; tumor necrosis factor receptor superfamily, member 10b" ID="ID_888439839" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPL: 1.29-fold Up; FDR = 0.353; PValue = 0.166; mean CPM = 11.54; periplakin" ID="ID_1489261836" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSNK1D: 1.1-fold Down; FDR = 0.378; PValue = 0.18; mean CPM = 93.44; casein kinase 1, delta" ID="ID_1647167523" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COMMD9: 1.11-fold Up; FDR = 0.396; PValue = 0.192; mean CPM = 23.54; COMM domain containing 9" ID="ID_1836553495" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1395686246" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KDELC2: 1.11-fold Up; FDR = 0.461; PValue = 0.232; mean CPM = 32.03; KDEL (Lys-Asp-Glu-Leu) containing 2" ID="ID_170061878" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PURA: 1.1-fold Down; FDR = 0.475; PValue = 0.242; mean CPM = 19.43; purine-rich element binding protein A" ID="ID_1821713852" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLOCK: 1.09-fold Up; FDR = 0.49; PValue = 0.251; mean CPM = 42.77; clock circadian regulator" ID="ID_485377922" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP1R7: 1.09-fold Down; FDR = 0.491; PValue = 0.253; mean CPM = 35.27; protein phosphatase 1, regulatory subunit 7" ID="ID_792610120" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYMS: 1.11-fold Up; FDR = 0.494; PValue = 0.254; mean CPM = 71.74; thymidylate synthetase" ID="ID_1932444583" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTBP1: 1.08-fold Down; FDR = 0.5; PValue = 0.258; mean CPM = 205.6; polypyrimidine tract binding protein 1" ID="ID_947849385" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOTCH2: 1.09-fold Down; FDR = 0.514; PValue = 0.268; mean CPM = 795.0; Notch homolog 2 (Drosophila)" ID="ID_582720162" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCI: 1.08-fold Up; FDR = 0.518; PValue = 0.271; mean CPM = 47.99; protein kinase C, iota" ID="ID_599623218" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HNRNPM: 1.08-fold Down; FDR = 0.521; PValue = 0.273; mean CPM = 171.6; heterogeneous nuclear ribonucleoprotein M" ID="ID_282844635" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLEKHC1: 1.08-fold Up; FDR = 0.529; PValue = 0.278; mean CPM = 251.5; fermitin family homolog 2 (Drosophila)" ID="ID_1347407026" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MBNL1: 1.08-fold Up; FDR = 0.574; PValue = 0.311; mean CPM = 371.7; muscleblind-like (Drosophila)" ID="ID_1652521285" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SRSF9: 1.07-fold Down; FDR = 0.595; PValue = 0.326; mean CPM = 49.60; Uncharacterized protein" ID="ID_204691652" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATG3: 1.07-fold Up; FDR = 0.653; PValue = 0.37; mean CPM = 66.70; ATG3 autophagy related 3 homolog (S. cerevisiae)" ID="ID_835989113" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DDX5: 1.07-fold Up; FDR = 0.662; PValue = 0.377; mean CPM = 756.3; DEAD (Asp-Glu-Ala-Asp) box polypeptide 5" ID="ID_465003233" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRMT1: 1.07-fold Up; FDR = 0.683; PValue = 0.394; mean CPM = 34.90; TRM1 tRNA methyltransferase 1 homolog (S. cerevisiae)" ID="ID_72194465" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP2A2: 1.06-fold Down; FDR = 0.705; PValue = 0.411; mean CPM = 361.0; ATPase, Ca++ transporting, cardiac muscle, slow twitch 2" ID="ID_1747562045" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LY6K: 1.41-fold Up; FDR = 0.737; PValue = 0.438; mean CPM = 0.8830; lymphocyte antigen 6 complex, locus K" ID="ID_1986945511" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP53INP1: 1.12-fold Up; FDR = 0.743; PValue = 0.444; mean CPM = 8.273; tumor protein p53 inducible nuclear protein 1" ID="ID_604105228" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMEM43: 1.05-fold Down; FDR = 0.783; PValue = 0.48; mean CPM = 121.5; transmembrane protein 43" ID="ID_1537165682" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SFRS13A: 1.49-fold Down; FDR = 0.79; PValue = 0.486; mean CPM = 0.8044; splicing factor, arginine/serine-rich 13A" ID="ID_1856451950" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMED7-TICAM2: 1.05-fold Down; FDR = 0.796; PValue = 0.493; mean CPM = 150.6; TMED7-TICAM2 readthrough" ID="ID_1430270874" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ABCF2: 1.05-fold Down; FDR = 0.8; PValue = 0.496; mean CPM = 75.45; ATP-binding cassette, sub-family F (GCN20), member 2" ID="ID_979320216" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC38A2: 1.05-fold Up; FDR = 0.808; PValue = 0.504; mean CPM = 193.5; solute carrier family 38, member 2" ID="ID_411299642" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMED10: 1.05-fold Down; FDR = 0.821; PValue = 0.52; mean CPM = 318.9; transmembrane emp24-like trafficking protein 10 (yeast)" ID="ID_1333029036" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP5C: 1.05-fold Up; FDR = 0.826; PValue = 0.526; mean CPM = 49.97; protein phosphatase 5, catalytic subunit" ID="ID_1400908049" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CUL4B: 1.04-fold Up; FDR = 0.836; PValue = 0.541; mean CPM = 53.38; cullin 4B" ID="ID_1905610670" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL6: 1.06-fold Down; FDR = 0.837; PValue = 0.542; mean CPM = 64.49; B-cell CLL/lymphoma 6" ID="ID_1568478334" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000023221: 1.32-fold Up; FDR = 0.854; PValue = 0.567; mean CPM = 0.7977" ID="ID_953197051" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NUFIP2: 1.04-fold Down; FDR = 0.854; PValue = 0.567; mean CPM = 77.45; nuclear fragile X mental retardation protein interacting protein 2" ID="ID_980855992" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TCL1A: 1.28-fold Up; FDR = 0.873; PValue = 0.591; mean CPM = 0.7961; T-cell leukemia/lymphoma 1A" ID="ID_520537225" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RARS: 1.04-fold Up; FDR = 0.888; PValue = 0.61; mean CPM = 124.3; arginyl-tRNA synthetase" ID="ID_469966772" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LCLAT1: 1.06-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 8.655; lysocardiolipin acyltransferase 1" ID="ID_519786127" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000024007: 1.24-fold Up; FDR = 0.898; PValue = 0.622; mean CPM = 0.8140; Uncharacterized protein" ID="ID_696223358" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MPZL1: 1.03-fold Up; FDR = 0.902; PValue = 0.639; mean CPM = 84.36; myelin protein zero-like 1" ID="ID_1074120061" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATRX: 1.03-fold Down; FDR = 0.903; PValue = 0.645; mean CPM = 98.18; alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae)" ID="ID_172562690" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PGC: 1.36-fold Down; FDR = 0.906; PValue = 0.668; mean CPM = 0.8398; progastricsin (pepsinogen C)" ID="ID_1459380520" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MRPS24: 1.03-fold Down; FDR = 0.909; PValue = 0.684; mean CPM = 36.51; mitochondrial ribosomal protein S24" ID="ID_379010647" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TERT: 1.35-fold Down; FDR = 0.909; PValue = 0.691; mean CPM = 0.8377; telomerase reverse transcriptase" ID="ID_1965958565" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCL: 1.03-fold Up; FDR = 0.909; PValue = 0.691; mean CPM = 392.4; nucleolin" ID="ID_857543352" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000011953: 1.14-fold Up; FDR = 0.911; PValue = 0.701; mean CPM = 0.7953; Uncharacterized protein" ID="ID_1265649166" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1C: 1.14-fold Up; FDR = 0.932; PValue = 0.743; mean CPM = 1.145; cyclin-dependent kinase inhibitor 1C (p57, Kip2)" ID="ID_281231760" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAT2A: 1.02-fold Up; FDR = 0.935; PValue = 0.747; mean CPM = 130.5; methionine adenosyltransferase II, alpha" ID="ID_1574760912" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB1: 1.02-fold Down; FDR = 0.936; PValue = 0.749; mean CPM = 62.61; transforming growth factor, beta 1" ID="ID_1792322550" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R4: 1.02-fold Down; FDR = 0.943; PValue = 0.763; mean CPM = 93.45; protein phosphatase 2A activator, regulatory subunit 4" ID="ID_737218064" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK5RAP3: 1.02-fold Down; FDR = 0.943; PValue = 0.764; mean CPM = 56.54; Uncharacterized protein" ID="ID_1458424644" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000018123: 1.02-fold Down; FDR = 0.964; PValue = 0.8; mean CPM = 57.60; Uncharacterized protein" ID="ID_197186824" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000018123: 1.02-fold Down; FDR = 0.964; PValue = 0.8; mean CPM = 57.60; Uncharacterized protein" ID="ID_424926059" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000013347: 1.15-fold Down; FDR = 0.971; PValue = 0.812; mean CPM = 0.8040; Pyruvate kinase" ID="ID_855445273" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPLAD1: 1.02-fold Up; FDR = 0.98; PValue = 0.825; mean CPM = 47.79; protein tyrosine phosphatase-like A domain containing 1" ID="ID_1767547367" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADPGK: 1.02-fold Down; FDR = 0.983; PValue = 0.83; mean CPM = 66.90; ADP-dependent glucokinase" ID="ID_846724032" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PGC: 1.14-fold Down; FDR = 0.985; PValue = 0.834; mean CPM = 0.8351; progastricsin (pepsinogen C)" ID="ID_823551032" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NEDD4: 1.01-fold Down; FDR = 1; PValue = 0.86; mean CPM = 49.99; neural precursor cell expressed, developmentally down-regulated 4" ID="ID_274248811" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PGM1: 1.01-fold Down; FDR = 1; PValue = 0.881; mean CPM = 75.42; phosphoglucomutase 1" ID="ID_1040742130" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000019192: 1.05-fold Up; FDR = 1; PValue = 0.901; mean CPM = 0.9655; Pyruvate kinase" ID="ID_97179771" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="POLR2C: 1.01-fold Up; FDR = 1; PValue = 0.901; mean CPM = 62.33; polymerase (RNA) II (DNA directed) polypeptide C, 33kDa" ID="ID_933690867" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000025363: 1.02-fold Up; FDR = 1; PValue = 0.907; mean CPM = 0.8201; Uncharacterized protein" ID="ID_453838289" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MPDU1: 1.01-fold Up; FDR = 1; PValue = 0.919; mean CPM = 43.22; Uncharacterized protein" ID="ID_1610686662" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ANXA2: 1.01-fold Up; FDR = 1; PValue = 0.921; mean CPM = 3870; Annexin" ID="ID_710728265" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTSC: 1.02-fold Up; FDR = 1; PValue = 0.932; mean CPM = 2.811; cathepsin C" ID="ID_1140411064" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CA12: 1.01-fold Up; FDR = 1; PValue = 0.94; mean CPM = 15.70; carbonic anhydrase XII" ID="ID_390824219" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GALNT1: 1.01-fold Down; FDR = 1; PValue = 0.946; mean CPM = 152.3; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)" ID="ID_942408504" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000025639: 1.01-fold Down; FDR = 1; PValue = 0.971; mean CPM = 0.9296; Uncharacterized protein" ID="ID_373518641" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAM1: No Change; FDR = 1; PValue = 0.98; mean CPM = 305.8; translocation associated membrane protein 1" ID="ID_650390276" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000028735: No Change; FDR = 1; PValue = 1; mean CPM = 0.7796; Uncharacterized protein" ID="ID_336821749" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Striated Muscle Contraction (WP383:Rev45112): FDR = 1.38e-10, PValue = 3.24e-11" ID="ID_918669533" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="MYOM1: 6.65-fold Down; FDR = 1.7e-13; PValue = 2.34e-15; mean CPM = 107.5; myomesin 1" ID="ID_333601106" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DMD: 2.29-fold Down; FDR = 6.37e-12; PValue = 1.28e-13; mean CPM = 17.66; Uncharacterized protein" ID="ID_3812005" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYH3: 3.39-fold Down; FDR = 5.36e-09; PValue = 2.17e-10; mean CPM = 6.410; myosin, heavy chain 3, skeletal muscle, embryonic" ID="ID_108118326" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TPM4: 1.8-fold Down; FDR = 1.34e-08; PValue = 5.96e-10; mean CPM = 1400; tropomyosin 4" ID="ID_1826179319" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYL9: 2.18-fold Down; FDR = 2.17e-08; PValue = 1.03e-09; mean CPM = 805.4; myosin, light chain 9, regulatory" ID="ID_747987187" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACTN4: 1.63-fold Down; FDR = 6.46e-08; PValue = 3.46e-09; mean CPM = 631.8; actinin, alpha 4" ID="ID_14074354" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DES: 9.53-fold Up; FDR = 7.57e-08; PValue = 4.1e-09; mean CPM = 59.19; desmin" ID="ID_405979321" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYH8: 4.72-fold Down; FDR = 3.49e-06; PValue = 2.9e-07; mean CPM = 5.170; myosin, heavy chain 8, skeletal muscle, perinatal" ID="ID_189720423" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYBPC3: 2.7-fold Down; FDR = 6.28e-06; PValue = 5.59e-07; mean CPM = 6.622; myosin binding protein C, cardiac" ID="ID_80559016" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TTN: 2.84-fold Down; FDR = 6.47e-06; PValue = 5.78e-07; mean CPM = 360.1; titin" ID="ID_1273666641" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMOD1: 3.73-fold Down; FDR = 6.41e-05; PValue = 7.52e-06; mean CPM = 1.614; tropomodulin 1" ID="ID_1825756518" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VIM: 1.54-fold Down; FDR = 0.000219; PValue = 3.01e-05; mean CPM = 3996; vimentin" ID="ID_1094608762" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACTA1: 5.36-fold Down; FDR = 0.000251; PValue = 3.52e-05; mean CPM = 5.880; Uncharacterized protein" ID="ID_1278911359" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TCAP: 1.74-fold Down; FDR = 0.00819; PValue = 0.00187; mean CPM = 2.747; titin-cap (telethonin)" ID="ID_381646157" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNNT1: 1.52-fold Up; FDR = 0.00827; PValue = 0.00189; mean CPM = 12.30; troponin T type 1 (skeletal, slow)" ID="ID_1127310508" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNNI3: 1.94-fold Up; FDR = 0.0102; PValue = 0.0024; mean CPM = 2.886; Uncharacterized protein" ID="ID_773814050" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACTC1: 2.5-fold Down; FDR = 0.0968; PValue = 0.0338; mean CPM = 0.9546; actin, alpha, cardiac muscle 1" ID="ID_376092870" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYBPC2: 2.05-fold Down; FDR = 0.115; PValue = 0.0414; mean CPM = 1.104; myosin binding protein C, fast type" ID="ID_525424425" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNNC2: 1.59-fold Down; FDR = 0.175; PValue = 0.0696; mean CPM = 1.542; troponin C type 2 (fast)" ID="ID_1422255265" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNNT2: 1.64-fold Down; FDR = 0.24; PValue = 0.103; mean CPM = 1.443; troponin T type 2 (cardiac)" ID="ID_269967157" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNNT3: 1.62-fold Down; FDR = 0.242; PValue = 0.104; mean CPM = 1.547; troponin T type 3 (skeletal, fast)" ID="ID_656873588" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYL3: 2-fold Down; FDR = 0.263; PValue = 0.115; mean CPM = 1.026; myosin, light chain 3, alkali; ventricular, skeletal, slow" ID="ID_1167906920" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TPM2: 1.85-fold Down; FDR = 0.59; PValue = 0.322; mean CPM = 0.8275; tropomyosin 2 (beta)" ID="ID_1294743398" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYL4: 1.32-fold Down; FDR = 0.787; PValue = 0.484; mean CPM = 0.9677; myosin, light chain 4, alkali; atrial, embryonic" ID="ID_530497394" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACTN2: 1.69-fold Down; FDR = 0.791; PValue = 0.488; mean CPM = 0.8357; actinin, alpha 2" ID="ID_266836020" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYL1: 1.65-fold Down; FDR = 0.81; PValue = 0.507; mean CPM = 0.8220; myosin, light chain 1, alkali; skeletal, fast" ID="ID_1741548182" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNNI2: 1.43-fold Down; FDR = 0.835; PValue = 0.538; mean CPM = 0.8240; Troponin I, fast-twitch isoform; Uncharacterized protein" ID="ID_716030417" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYL2: 1.15-fold Up; FDR = 0.909; PValue = 0.69; mean CPM = 0.7911; myosin, light chain 2, regulatory, cardiac, slow" ID="ID_1252191845" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYH6: 1.11-fold Up; FDR = 0.975; PValue = 0.817; mean CPM = 1.001; myosin, heavy chain 6, cardiac muscle, alpha" ID="ID_573815034" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNNC1: 1.03-fold Up; FDR = 1; PValue = 0.898; mean CPM = 11.38; troponin C type 1 (slow)" ID="ID_1178350251" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Integrated Breast Cancer Pathway (WP1984:Rev44857): FDR = 1.75e-10, PValue = 4.2e-11" ID="ID_982699013" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1337716416" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_1309355831" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASGRP3: 7.1-fold Up; FDR = 6.93e-13; PValue = 1.1e-14; mean CPM = 7.525; RAS guanyl releasing protein 3 (calcium and DAG-regulated)" ID="ID_907383533" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PML: 2.25-fold Up; FDR = 6.36e-11; PValue = 1.6e-12; mean CPM = 94.89; Uncharacterized protein" ID="ID_1935635988" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BID: 1.66-fold Up; FDR = 5.41e-09; PValue = 2.19e-10; mean CPM = 35.19; BH3 interacting domain death agonist" ID="ID_1866605660" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGFR: 1.84-fold Up; FDR = 6.71e-09; PValue = 2.77e-10; mean CPM = 68.58; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)" ID="ID_724864326" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRS1: 2.78-fold Up; FDR = 7.67e-09; PValue = 3.19e-10; mean CPM = 26.55; Uncharacterized protein" ID="ID_1108814211" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RB1: 1.65-fold Up; FDR = 6.01e-08; PValue = 3.2e-09; mean CPM = 59.24; retinoblastoma 1" ID="ID_1803556032" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ESR1: 5.04-fold Up; FDR = 6.62e-08; PValue = 3.55e-09; mean CPM = 2.845; estrogen receptor 1" ID="ID_216014541" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_307159807" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMARCA4: 1.49-fold Down; FDR = 3.19e-07; PValue = 2.01e-08; mean CPM = 157.3; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4" ID="ID_1661169048" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1350522970" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BACH1: 1.69-fold Up; FDR = 3.53e-06; PValue = 2.94e-07; mean CPM = 503.5; BTB and CNC homology 1, basic leucine zipper transcription factor 1" ID="ID_1827156896" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF1: 1.51-fold Up; FDR = 5.28e-06; PValue = 4.58e-07; mean CPM = 22.13; activating transcription factor 1" ID="ID_474776682" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAD50: 1.54-fold Up; FDR = 6.76e-06; PValue = 6.08e-07; mean CPM = 45.86; RAD50 homolog (S. cerevisiae)" ID="ID_495236392" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TSC2: 1.44-fold Down; FDR = 1e-05; PValue = 9.42e-07; mean CPM = 124.0; tuberous sclerosis 2" ID="ID_652525516" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ANXA1: 1.47-fold Up; FDR = 1.47e-05; PValue = 1.45e-06; mean CPM = 598.2; annexin A1" ID="ID_53953075" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPP38: 1.65-fold Up; FDR = 1.67e-05; PValue = 1.67e-06; mean CPM = 9.750; ribonuclease P/MRP 38kDa subunit" ID="ID_233720206" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLK1: 2.25-fold Down; FDR = 3.23e-05; PValue = 3.46e-06; mean CPM = 27.29; polo-like kinase 1 (Drosophila)" ID="ID_1922436459" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XRCC3: 1.62-fold Down; FDR = 9.98e-05; PValue = 1.23e-05; mean CPM = 10.15; X-ray repair complementing defective repair in Chinese hamster cells 3" ID="ID_1191180722" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZNF655: 1.36-fold Up; FDR = 0.000123; PValue = 1.57e-05; mean CPM = 51.27; zinc finger protein 655" ID="ID_1449761585" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TPR: 1.36-fold Up; FDR = 0.000146; PValue = 1.91e-05; mean CPM = 281.7; translocated promoter region (to activated MET oncogene)" ID="ID_1304017255" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VEGFA: 1.47-fold Up; FDR = 0.000317; PValue = 4.59e-05; mean CPM = 463.7; vascular endothelial growth factor A" ID="ID_922808282" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AQP7: 3.27-fold Down; FDR = 0.000494; PValue = 7.55e-05; mean CPM = 1.350; aquaporin 7" ID="ID_525202850" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AR: 2.06-fold Up; FDR = 0.000527; PValue = 8.13e-05; mean CPM = 4.804; Macaca mulatta androgen receptor (AR), mRNA." ID="ID_926721449" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAD: 1.36-fold Down; FDR = 0.000605; PValue = 9.52e-05; mean CPM = 48.46; BCL2-associated agonist of cell death" ID="ID_1926869493" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7CL: 1.93-fold Down; FDR = 0.000854; PValue = 0.000141; mean CPM = 52.11; MAP3K7 C-terminal like" ID="ID_1285357026" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NUP85: 1.31-fold Down; FDR = 0.000897; PValue = 0.000149; mean CPM = 49.44; nucleoporin 85kDa" ID="ID_1139705740" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOXO1: 1.49-fold Down; FDR = 0.00109; PValue = 0.000186; mean CPM = 11.95; forkhead box O1" ID="ID_549944267" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTOR: 1.3-fold Down; FDR = 0.00117; PValue = 0.000201; mean CPM = 107.5; mechanistic target of rapamycin (serine/threonine kinase)" ID="ID_1635794801" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AHR: 1.56-fold Up; FDR = 0.00124; PValue = 0.000215; mean CPM = 89.50; aryl hydrocarbon receptor" ID="ID_1567067428" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ALKBH1: 1.42-fold Up; FDR = 0.00129; PValue = 0.000225; mean CPM = 12.71; alkB, alkylation repair homolog 1 (E. coli)" ID="ID_1072537405" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIAS1: 1.3-fold Up; FDR = 0.00259; PValue = 0.000498; mean CPM = 29.99; protein inhibitor of activated STAT, 1" ID="ID_73292094" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RALA: 1.28-fold Up; FDR = 0.00322; PValue = 0.000638; mean CPM = 42.83; v-ral simian leukemia viral oncogene homolog A (ras related)" ID="ID_920220827" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BRCA1: 1.38-fold Up; FDR = 0.00331; PValue = 0.000658; mean CPM = 39.12; Macaca mulatta breast cancer 1, early onset (BRCA1), mRNA." ID="ID_131821159" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNB1IP1: 1.69-fold Up; FDR = 0.00354; PValue = 0.000714; mean CPM = 4.126; cyclin B1 interacting protein 1" ID="ID_521221630" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMEK2: 1.27-fold Up; FDR = 0.00374; PValue = 0.00076; mean CPM = 70.26; SMEK homolog 2, suppressor of mek1 (Dictyostelium)" ID="ID_119035168" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MDM2: 1.32-fold Up; FDR = 0.00555; PValue = 0.00119; mean CPM = 148.6; Uncharacterized protein" ID="ID_1586116142" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD7: 1.33-fold Down; FDR = 0.00568; PValue = 0.00123; mean CPM = 67.59; SMAD family member 7" ID="ID_1506670875" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAX: 1.28-fold Up; FDR = 0.00569; PValue = 0.00123; mean CPM = 29.78; MYC associated factor X" ID="ID_630010969" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IMPA1: 1.31-fold Up; FDR = 0.00576; PValue = 0.00125; mean CPM = 21.96; inositol(myo)-1(or 4)-monophosphatase 1" ID="ID_1689026971" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP1: 3.27-fold Down; FDR = 0.00611; PValue = 0.00133; mean CPM = 110.4; matrix metallopeptidase 1 (interstitial collagenase)" ID="ID_53676917" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HMGCR: 1.25-fold Down; FDR = 0.00707; PValue = 0.00157; mean CPM = 46.64; 3-hydroxy-3-methylglutaryl-CoA reductase" ID="ID_572327307" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FAU: 1.26-fold Up; FDR = 0.00709; PValue = 0.00158; mean CPM = 484.5; Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed" ID="ID_1888530939" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCOA3: 1.24-fold Up; FDR = 0.0123; PValue = 0.00297; mean CPM = 178.3; nuclear receptor coactivator 3" ID="ID_324217632" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SP1: 1.23-fold Up; FDR = 0.0139; PValue = 0.00344; mean CPM = 75.49; Transcription factor Sp1 isoform a; Uncharacterized protein" ID="ID_1235101175" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC1: 1.25-fold Up; FDR = 0.0159; PValue = 0.00403; mean CPM = 27.51; histone deacetylase 1" ID="ID_1917460382" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK2: 1.23-fold Down; FDR = 0.0194; PValue = 0.00507; mean CPM = 36.76; cyclin-dependent kinase 2" ID="ID_322179509" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_271159620" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHEK2: 1.38-fold Up; FDR = 0.0228; PValue = 0.00613; mean CPM = 20.56; checkpoint kinase 2" ID="ID_1681977934" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BARD1: 1.44-fold Up; FDR = 0.0245; PValue = 0.00666; mean CPM = 7.836; BRCA1 associated RING domain 1" ID="ID_1918491721" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLK3: 1.27-fold Down; FDR = 0.0251; PValue = 0.00684; mean CPM = 26.43; polo-like kinase 3 (Drosophila)" ID="ID_486906781" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_249697075" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NAB1: 1.21-fold Up; FDR = 0.0276; PValue = 0.00765; mean CPM = 48.54; NGFI-A binding protein 1 (EGR1 binding protein 1)" ID="ID_1974248470" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB1: 1.21-fold Up; FDR = 0.0313; PValue = 0.00884; mean CPM = 36.07; cAMP responsive element binding protein 1" ID="ID_1200806805" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="USP16: 1.21-fold Up; FDR = 0.0319; PValue = 0.00906; mean CPM = 79.56; ubiquitin specific peptidase 16" ID="ID_40523601" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRADD: 1.22-fold Up; FDR = 0.0319; PValue = 0.00907; mean CPM = 34.75; TNFRSF1A-associated via death domain" ID="ID_1609591253" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD2: 1.2-fold Up; FDR = 0.034; PValue = 0.00976; mean CPM = 57.10; SMAD family member 2" ID="ID_1770934016" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GADD45A: 1.22-fold Up; FDR = 0.0344; PValue = 0.00989; mean CPM = 127.8; growth arrest and DNA-damage-inducible, alpha" ID="ID_1218879816" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFBR1: 1.2-fold Up; FDR = 0.037; PValue = 0.0108; mean CPM = 90.92; transforming growth factor, beta receptor 1" ID="ID_761464923" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYP19A1: 2-fold Down; FDR = 0.0384; PValue = 0.0113; mean CPM = 1.909; cytochrome P450, family 19, subfamily A, polypeptide 1" ID="ID_897657211" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITPKC: 1.23-fold Down; FDR = 0.0389; PValue = 0.0114; mean CPM = 19.77; inositol 1,4,5-trisphosphate 3-kinase C" ID="ID_337002246" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1611075123" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KRAS: 1.35-fold Down; FDR = 0.0401; PValue = 0.0119; mean CPM = 13.10; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog" ID="ID_589385392" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="E2F1: 1.44-fold Down; FDR = 0.0425; PValue = 0.0127; mean CPM = 8.857; E2F transcription factor 1" ID="ID_1392862534" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTNNB1: 1.2-fold Up; FDR = 0.0498; PValue = 0.0153; mean CPM = 558.3; catenin (cadherin-associated protein), beta 1, 88kDa" ID="ID_136798649" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WEE1: 1.33-fold Down; FDR = 0.0505; PValue = 0.0156; mean CPM = 10.37; WEE1 homolog (S. pombe)" ID="ID_172876823" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PKIA: 1.69-fold Up; FDR = 0.0525; PValue = 0.0163; mean CPM = 3.292; protein kinase (cAMP-dependent, catalytic) inhibitor alpha" ID="ID_1582763347" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TSC1: 1.19-fold Down; FDR = 0.0564; PValue = 0.0177; mean CPM = 38.34; tuberous sclerosis 1" ID="ID_1888415253" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFBR2: 1.19-fold Up; FDR = 0.0643; PValue = 0.0208; mean CPM = 350.8; transforming growth factor, beta receptor II (70/80kDa)" ID="ID_548057782" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DAG1: 1.54-fold Down; FDR = 0.0661; PValue = 0.0214; mean CPM = 3.013; dystroglycan 1 (dystrophin-associated glycoprotein 1)" ID="ID_390618677" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_929716503" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAD51: 1.42-fold Up; FDR = 0.0689; PValue = 0.0225; mean CPM = 7.808; RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)" ID="ID_407324456" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DCAKD: 1.21-fold Up; FDR = 0.074; PValue = 0.0245; mean CPM = 18.20; dephospho-CoA kinase domain containing" ID="ID_904903991" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAD54L: 1.3-fold Down; FDR = 0.0763; PValue = 0.0255; mean CPM = 7.674; RAD54-like (S. cerevisiae)" ID="ID_655329393" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZMIZ1: 1.19-fold Down; FDR = 0.0886; PValue = 0.0303; mean CPM = 45.42; zinc finger, MIZ-type containing 1" ID="ID_1289376129" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1A: 1.17-fold Up; FDR = 0.0888; PValue = 0.0304; mean CPM = 37.16; RAP1A, member of RAS oncogene family" ID="ID_546507350" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FADD: 1.18-fold Down; FDR = 0.0936; PValue = 0.0324; mean CPM = 30.89; Uncharacterized protein" ID="ID_474113221" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_37134114" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3A: 1.18-fold Down; FDR = 0.097; PValue = 0.0338; mean CPM = 25.14; Glycogen synthase kinase-3 alpha; Uncharacterized protein" ID="ID_860186059" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CERK: 1.17-fold Down; FDR = 0.101; PValue = 0.0354; mean CPM = 28.29; ceramide kinase" ID="ID_445978087" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYT1: 2.34-fold Down; FDR = 0.113; PValue = 0.0404; mean CPM = 0.9287; myelin transcription factor 1" ID="ID_1575962379" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND1: 1.17-fold Up; FDR = 0.121; PValue = 0.0443; mean CPM = 867.3; cyclin D1" ID="ID_119759225" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1137158149" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTEN: 1.14-fold Up; FDR = 0.166; PValue = 0.065; mean CPM = 89.60; phosphatase and tensin homolog" ID="ID_241204751" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SIRT1: 1.17-fold Up; FDR = 0.182; PValue = 0.0729; mean CPM = 15.83; sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae)" ID="ID_603138247" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHEB: 1.13-fold Up; FDR = 0.193; PValue = 0.0785; mean CPM = 118.9; Ras homolog enriched in brain" ID="ID_599318667" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BRAF: 1.14-fold Down; FDR = 0.228; PValue = 0.0964; mean CPM = 24.98; v-raf murine sarcoma viral oncogene homolog B1" ID="ID_1760555095" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FER: 1.12-fold Down; FDR = 0.254; PValue = 0.11; mean CPM = 53.47; fer (fps/fes related) tyrosine kinase" ID="ID_970841096" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LGALS13: 1.62-fold Down; FDR = 0.254; PValue = 0.11; mean CPM = 1.415; lectin, galactoside-binding, soluble, 13" ID="ID_138147068" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATR: 1.12-fold Up; FDR = 0.256; PValue = 0.111; mean CPM = 44.19; Uncharacterized protein" ID="ID_1886696033" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MSH2: 1.17-fold Up; FDR = 0.287; PValue = 0.128; mean CPM = 18.63; mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)" ID="ID_81278154" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOXA1: 1.69-fold Up; FDR = 0.29; PValue = 0.13; mean CPM = 1.099; NADPH oxidase activator 1" ID="ID_1375816830" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BRCA2: 1.26-fold Down; FDR = 0.307; PValue = 0.139; mean CPM = 13.92; breast cancer 2, early onset" ID="ID_258024778" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EP300: 1.11-fold Up; FDR = 0.312; PValue = 0.142; mean CPM = 162.8; E1A binding protein p300" ID="ID_1312655043" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP1: 1.12-fold Down; FDR = 0.351; PValue = 0.165; mean CPM = 17.96; TGF-beta activated kinase 1/MAP3K7 binding protein 1" ID="ID_493834602" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP53: 1.11-fold Down; FDR = 0.364; PValue = 0.172; mean CPM = 33.25; tumor protein p53" ID="ID_1419678614" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSNK1D: 1.1-fold Down; FDR = 0.378; PValue = 0.18; mean CPM = 93.44; casein kinase 1, delta" ID="ID_1248224947" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NF1: 1.1-fold Up; FDR = 0.383; PValue = 0.184; mean CPM = 199.1; neurofibromin 1" ID="ID_711232184" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2: 1.48-fold Up; FDR = 0.384; PValue = 0.184; mean CPM = 1.344; Uncharacterized protein" ID="ID_1341195020" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHO: 1.78-fold Down; FDR = 0.395; PValue = 0.191; mean CPM = 0.8794; rhodopsin" ID="ID_1268236996" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RRAS: 1.1-fold Up; FDR = 0.415; PValue = 0.203; mean CPM = 223.0; related RAS viral (r-ras) oncogene homolog" ID="ID_262330333" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ABL1: 1.09-fold Up; FDR = 0.43; PValue = 0.213; mean CPM = 178.0; c-abl oncogene 1, receptor tyrosine kinase" ID="ID_1635282054" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MRE11A: 1.11-fold Up; FDR = 0.467; PValue = 0.236; mean CPM = 15.10; MRE11 meiotic recombination 11 homolog A (S. cerevisiae)" ID="ID_410759624" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="USP21: 1.1-fold Down; FDR = 0.515; PValue = 0.268; mean CPM = 15.94; ubiquitin specific peptidase 21" ID="ID_1816431488" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="UBE2F: 1.09-fold Up; FDR = 0.56; PValue = 0.301; mean CPM = 16.45; ubiquitin-conjugating enzyme E2F (putative)" ID="ID_72185360" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TFPI: 1.09-fold Down; FDR = 0.606; PValue = 0.335; mean CPM = 64.96; tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)" ID="ID_1833569171" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDC42: 1.07-fold Down; FDR = 0.608; PValue = 0.335; mean CPM = 91.67; cell division cycle 42" ID="ID_790859416" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="USP38: 1.06-fold Down; FDR = 0.661; PValue = 0.376; mean CPM = 54.23; ubiquitin specific peptidase 38" ID="ID_1838901289" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATM: 1.06-fold Down; FDR = 0.67; PValue = 0.383; mean CPM = 65.17; ataxia telangiectasia mutated" ID="ID_834423155" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PHB: 1.06-fold Up; FDR = 0.734; PValue = 0.435; mean CPM = 111.0; prohibitin" ID="ID_1263852465" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AURKA: 1.12-fold Down; FDR = 0.746; PValue = 0.446; mean CPM = 12.28; aurora kinase A" ID="ID_823406025" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD1: 1.07-fold Up; FDR = 0.768; PValue = 0.466; mean CPM = 16.45; SMAD family member 1" ID="ID_1757291693" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_181051024" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BLM: 1.06-fold Up; FDR = 0.787; PValue = 0.484; mean CPM = 17.02; Bloom syndrome, RecQ helicase-like" ID="ID_506236056" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FILIP1: 1.25-fold Down; FDR = 0.807; PValue = 0.504; mean CPM = 1.285; filamin A interacting protein 1" ID="ID_1348602301" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAX: 1.05-fold Up; FDR = 0.809; PValue = 0.506; mean CPM = 162.4; Uncharacterized protein" ID="ID_105041328" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDC25A: 1.07-fold Down; FDR = 0.814; PValue = 0.511; mean CPM = 10.16; cell division cycle 25 homolog A (S. pombe)" ID="ID_1916343959" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_769025623" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK4: 1.04-fold Up; FDR = 0.899; PValue = 0.626; mean CPM = 65.45; cyclin-dependent kinase 4" ID="ID_252438276" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BMPR1A: 1.04-fold Up; FDR = 0.903; PValue = 0.641; mean CPM = 36.13; bone morphogenetic protein receptor, type IA" ID="ID_249971506" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AC093227.1: 1.16-fold Down; FDR = 0.903; PValue = 0.647; mean CPM = 0.7894; Putative uncharacterized protein ENSP00000403930" ID="ID_1731384770" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RALGAPA1: 1.03-fold Up; FDR = 0.903; PValue = 0.65; mean CPM = 40.05; Ral GTPase activating protein, alpha subunit 1 (catalytic)" ID="ID_1115821324" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD4: 1.03-fold Down; FDR = 0.906; PValue = 0.666; mean CPM = 43.02; SMAD family member 4" ID="ID_36351644" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIGR: 1.3-fold Down; FDR = 0.91; PValue = 0.693; mean CPM = 0.8409; polymeric immunoglobulin receptor" ID="ID_118295517" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK1: 1.03-fold Down; FDR = 0.911; PValue = 0.705; mean CPM = 18.65; p21 protein (Cdc42/Rac)-activated kinase 1" ID="ID_1832121817" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MSH6: 1.03-fold Down; FDR = 0.914; PValue = 0.712; mean CPM = 49.75; mutS homolog 6 (E. coli)" ID="ID_945894975" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DHTKD1: 1.04-fold Down; FDR = 0.918; PValue = 0.719; mean CPM = 7.056; dehydrogenase E1 and transketolase domain containing 1" ID="ID_1219459382" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GDI1: 1.03-fold Down; FDR = 0.92; PValue = 0.722; mean CPM = 108.8; GDP dissociation inhibitor 1" ID="ID_124900078" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ERAL1: 1.02-fold Down; FDR = 0.942; PValue = 0.76; mean CPM = 30.69; Era G-protein-like 1 (E. coli)" ID="ID_321740497" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K13: 1.03-fold Up; FDR = 0.962; PValue = 0.796; mean CPM = 6.973; mitogen-activated protein kinase kinase kinase 13" ID="ID_1877221851" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_72203699" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRN: 1.02-fold Down; FDR = 0.968; PValue = 0.808; mean CPM = 437.0; granulin" ID="ID_1269668541" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASGEF1A: 1.09-fold Up; FDR = 0.98; PValue = 0.824; mean CPM = 1.044; RasGEF domain family, member 1A" ID="ID_1143097232" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDH1: 1.06-fold Down; FDR = 1; PValue = 0.899; mean CPM = 0.8823; cadherin 1, type 1, E-cadherin (epithelial)" ID="ID_290457803" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP9: 1.01-fold Up; FDR = 1; PValue = 0.908; mean CPM = 19.86; caspase 9, apoptosis-related cysteine peptidase" ID="ID_1104983214" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK7: 1.01-fold Up; FDR = 1; PValue = 0.917; mean CPM = 28.20; cyclin-dependent kinase 7" ID="ID_163335658" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STK11: 1.01-fold Up; FDR = 1; PValue = 0.918; mean CPM = 47.98; serine/threonine kinase 11" ID="ID_1673380044" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAKMIP1: 1.04-fold Up; FDR = 1; PValue = 0.963; mean CPM = 0.8769; janus kinase and microtubule interacting protein 1" ID="ID_394928942" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BMPR2: No Change; FDR = 1; PValue = 0.974; mean CPM = 136.9; Bone morphogenetic protein receptor type-2; Uncharacterized protein" ID="ID_114959154" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000005036: 1.07-fold Up; FDR = 1; PValue = 1; mean CPM = 0.8093; Uncharacterized protein" ID="ID_1826683174" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Endochondral Ossification (WP474:Rev45241): FDR = 5.66e-10, PValue = 1.39e-10" ID="ID_530762769" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1437943862" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHST11: 1.89-fold Down; FDR = 5.08e-11; PValue = 1.26e-12; mean CPM = 25.95; carbohydrate (chondroitin 4) sulfotransferase 11" ID="ID_1424613004" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLAU: 3.37-fold Down; FDR = 1.56e-10; PValue = 4.33e-12; mean CPM = 18.78; plasminogen activator, urokinase" ID="ID_1157076891" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MGP: 11.1-fold Down; FDR = 1.95e-10; PValue = 5.56e-12; mean CPM = 46.22; matrix Gla protein" ID="ID_1889509601" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SERPINH1: 2.33-fold Down; FDR = 3.72e-10; PValue = 1.13e-11; mean CPM = 1580; serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)" ID="ID_1098574242" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACAN: 8.6-fold Down; FDR = 9.08e-09; PValue = 3.88e-10; mean CPM = 593.8; aggrecan" ID="ID_1844902905" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF2: 2.42-fold Up; FDR = 9.98e-09; PValue = 4.31e-10; mean CPM = 134.8; fibroblast growth factor 2 (basic)" ID="ID_1704255989" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOX9: 3.15-fold Down; FDR = 1.96e-06; PValue = 1.53e-07; mean CPM = 6.885; SRY (sex determining region Y)-box 9" ID="ID_1714293973" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGFR3: 3.85-fold Down; FDR = 2.66e-06; PValue = 2.13e-07; mean CPM = 2.800; fibroblast growth factor receptor 3" ID="ID_1117567237" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_415498271" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1: 5.76-fold Down; FDR = 6.73e-06; PValue = 6.04e-07; mean CPM = 1.536; insulin-like growth factor 1 (somatomedin C)" ID="ID_1055630498" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1R: 1.51-fold Down; FDR = 1.02e-05; PValue = 9.61e-07; mean CPM = 213.2; insulin-like growth factor 1 receptor" ID="ID_1795586963" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFT88: 1.43-fold Up; FDR = 7.29e-05; PValue = 8.71e-06; mean CPM = 25.37; intraflagellar transport 88 homolog (Chlamydomonas)" ID="ID_1696226852" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPP1: 2.25-fold Down; FDR = 7.74e-05; PValue = 9.29e-06; mean CPM = 35.33; secreted phosphoprotein 1" ID="ID_924829026" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACA: 1.36-fold Down; FDR = 0.000167; PValue = 2.22e-05; mean CPM = 37.75; protein kinase, cAMP-dependent, catalytic, alpha" ID="ID_1627475031" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VEGFA: 1.47-fold Up; FDR = 0.000317; PValue = 4.59e-05; mean CPM = 463.7; vascular endothelial growth factor A" ID="ID_1243350617" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALM3: 1.41-fold Down; FDR = 0.000714; PValue = 0.000115; mean CPM = 94.24; calmodulin 3 (phosphorylase kinase, delta)" ID="ID_6443933" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADAMTS1: 1.65-fold Down; FDR = 0.000821; PValue = 0.000134; mean CPM = 712.2; ADAM metallopeptidase with thrombospondin type 1 motif, 1" ID="ID_51212156" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP9: 4.49-fold Down; FDR = 0.00222; PValue = 0.000419; mean CPM = 6.597; matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)" ID="ID_471751747" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FRZB: 2.1-fold Up; FDR = 0.00475; PValue = 0.001; mean CPM = 4.661; frizzled-related protein" ID="ID_1915572822" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC4: 1.38-fold Down; FDR = 0.00526; PValue = 0.00112; mean CPM = 48.60; histone deacetylase 4" ID="ID_948368560" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HMGCS1: 1.31-fold Down; FDR = 0.00578; PValue = 0.00125; mean CPM = 19.39; 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)" ID="ID_589849620" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL10A1: 2.53-fold Down; FDR = 0.0119; PValue = 0.00286; mean CPM = 1.365; collagen, type X, alpha 1" ID="ID_1635614995" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1748716809" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLAT: 1.37-fold Down; FDR = 0.034; PValue = 0.00976; mean CPM = 76.44; plasminogen activator, tissue" ID="ID_1360569195" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL2A1: 2.38-fold Down; FDR = 0.0368; PValue = 0.0107; mean CPM = 1.117; Uncharacterized protein" ID="ID_665499877" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSH-3: 2.19-fold Up; FDR = 0.0771; PValue = 0.0258; mean CPM = 1.335; Macaca mulatta chorionic somatommamotropin hormone 3 (CSH-3), mRNA." ID="ID_1085945049" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTH1R: 2-fold Down; FDR = 0.0838; PValue = 0.0284; mean CPM = 1.299; parathyroid hormone 1 receptor" ID="ID_658112376" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BMP6: 1.74-fold Down; FDR = 0.0895; PValue = 0.0307; mean CPM = 2.386; bone morphogenetic protein 6" ID="ID_1320014937" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALM1: 1.18-fold Down; FDR = 0.104; PValue = 0.0368; mean CPM = 292.9; calmodulin 1 (phosphorylase kinase, delta)" ID="ID_804526734" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGFR1: 1.15-fold Down; FDR = 0.139; PValue = 0.0525; mean CPM = 89.41; fibroblast growth factor receptor 1" ID="ID_64126728" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTSL2: 2.28-fold Down; FDR = 0.143; PValue = 0.0541; mean CPM = 0.9217; cathepsin L2" ID="ID_1562974986" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GLI3: 1.21-fold Down; FDR = 0.211; PValue = 0.0875; mean CPM = 42.23; GLI family zinc finger 3" ID="ID_1843061592" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTCH1: 1.14-fold Down; FDR = 0.32; PValue = 0.147; mean CPM = 13.18; patched homolog 1 (Drosophila)" ID="ID_148641270" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RUNX2: 1.24-fold Down; FDR = 0.328; PValue = 0.152; mean CPM = 8.937; runt-related transcription factor 2" ID="ID_534606492" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALM1: 1.11-fold Up; FDR = 0.343; PValue = 0.16; mean CPM = 412.7; Calmodulin; Uncharacterized protein" ID="ID_561134082" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENPP1: 1.2-fold Down; FDR = 0.346; PValue = 0.162; mean CPM = 147.6; ectonucleotide pyrophosphatase/phosphodiesterase 1" ID="ID_867771272" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADAMTS5: 1.26-fold Down; FDR = 0.354; PValue = 0.166; mean CPM = 36.26; ADAM metallopeptidase with thrombospondin type 1 motif, 5" ID="ID_496979546" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MEF2C: 1.24-fold Down; FDR = 0.357; PValue = 0.168; mean CPM = 6.816; myocyte enhancer factor 2C" ID="ID_1708141654" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GHR: 1.23-fold Up; FDR = 0.369; PValue = 0.175; mean CPM = 6.312; growth hormone receptor" ID="ID_1443917208" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAB39: 1.11-fold Up; FDR = 0.371; PValue = 0.176; mean CPM = 33.59; calcium binding protein 39" ID="ID_1633795167" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF2: 1.42-fold Up; FDR = 0.383; PValue = 0.183; mean CPM = 31.20; insulin-like growth factor 2 (somatomedin A)" ID="ID_1852164597" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THRA: 1.12-fold Down; FDR = 0.401; PValue = 0.195; mean CPM = 14.87; thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)" ID="ID_994390821" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RUNX3: 1.41-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 1.666; runt-related transcription factor 3" ID="ID_1264866230" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOX5: 1.4-fold Up; FDR = 0.536; PValue = 0.284; mean CPM = 1.420; SRY (sex determining region Y)-box 5" ID="ID_339215834" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF18: 1.55-fold Down; FDR = 0.548; PValue = 0.293; mean CPM = 0.9359; fibroblast growth factor 18" ID="ID_122785356" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ALPL: 1.27-fold Up; FDR = 0.625; PValue = 0.348; mean CPM = 2.290; alkaline phosphatase, liver/bone/kidney" ID="ID_430454222" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DDR2: 1.07-fold Up; FDR = 0.633; PValue = 0.355; mean CPM = 236.3; discoidin domain receptor tyrosine kinase 2" ID="ID_329510161" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADAMTS4: 1.18-fold Down; FDR = 0.655; PValue = 0.372; mean CPM = 6.172; ADAM metallopeptidase with thrombospondin type 1 motif, 4" ID="ID_1767274416" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOX6: 1.32-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 1.240; SRY (sex determining region Y)-box 6" ID="ID_1190532688" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IHH: 1.37-fold Down; FDR = 0.68; PValue = 0.391; mean CPM = 1.025; Indian hedgehog homolog (Drosophila)" ID="ID_691687517" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CST5: 1.61-fold Down; FDR = 0.807; PValue = 0.504; mean CPM = 0.8117; cystatin D" ID="ID_832612028" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC38A2: 1.05-fold Up; FDR = 0.808; PValue = 0.504; mean CPM = 193.5; solute carrier family 38, member 2" ID="ID_314285899" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BMPR1A: 1.04-fold Up; FDR = 0.903; PValue = 0.641; mean CPM = 36.13; bone morphogenetic protein receptor, type IA" ID="ID_479822933" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB2: 1.05-fold Down; FDR = 0.903; PValue = 0.655; mean CPM = 110.8; transforming growth factor, beta 2" ID="ID_413560196" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NKX3-2: 1.35-fold Up; FDR = 0.925; PValue = 0.731; mean CPM = 0.8228; NK3 homeobox 2" ID="ID_60055460" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1C: 1.14-fold Up; FDR = 0.932; PValue = 0.743; mean CPM = 1.145; cyclin-dependent kinase inhibitor 1C (p57, Kip2)" ID="ID_887502683" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB1: 1.02-fold Down; FDR = 0.936; PValue = 0.749; mean CPM = 62.61; transforming growth factor, beta 1" ID="ID_1224345799" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016883: 1.11-fold Down; FDR = 0.97; PValue = 0.811; mean CPM = 0.8838; Uncharacterized protein" ID="ID_706119120" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTHLH: 1.13-fold Down; FDR = 1; PValue = 0.935; mean CPM = 0.8502; Uncharacterized protein" ID="ID_1390245309" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SCIN: 1.04-fold Up; FDR = 1; PValue = 0.951; mean CPM = 0.8773; scinderin" ID="ID_1501457857" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BMP7: 1.01-fold Up; FDR = 1; PValue = 0.994; mean CPM = 0.8010; bone morphogenetic protein 7" ID="ID_370350128" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTH: No Change; FDR = 1; PValue = 1; mean CPM = 0.7843; parathyroid hormone" ID="ID_208921971" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Osteoclast Signaling (WP12:Rev45320): FDR = 7.86e-10, PValue = 1.97e-10" ID="ID_1553561957" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="ITGB3: 5.02-fold Down; FDR = 1.72e-09; PValue = 6.17e-11; mean CPM = 43.21; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)" ID="ID_1605377163" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AIMP2: 1.51-fold Down; FDR = 2.05e-06; PValue = 1.6e-07; mean CPM = 43.90; aminoacyl tRNA synthetase complex-interacting multifunctional protein 2" ID="ID_601561830" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_647377351" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP6V1G1: 1.37-fold Up; FDR = 6.07e-05; PValue = 7.07e-06; mean CPM = 77.29; ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1" ID="ID_490639774" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPP1: 2.25-fold Down; FDR = 7.74e-05; PValue = 9.29e-06; mean CPM = 35.33; secreted phosphoprotein 1" ID="ID_257278131" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C17orf57: 5.51-fold Down; FDR = 0.000238; PValue = 3.33e-05; mean CPM = 1.571; EF-hand domain-containing protein C17orf57" ID="ID_1362938264" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTSK: 1.62-fold Down; FDR = 0.00104; PValue = 0.000176; mean CPM = 20.16; cathepsin K" ID="ID_1798007018" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR1: 1.27-fold Up; FDR = 0.0101; PValue = 0.00237; mean CPM = 82.39; Uncharacterized protein" ID="ID_1060553414" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFB: 1.97-fold Down; FDR = 0.0133; PValue = 0.00326; mean CPM = 2.424; platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)" ID="ID_898368131" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF11: 1.8-fold Up; FDR = 0.039; PValue = 0.0115; mean CPM = 2.535; tumor necrosis factor (ligand) superfamily, member 11" ID="ID_1119910682" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF11B: 1.31-fold Down; FDR = 0.121; PValue = 0.0439; mean CPM = 722.1; Uncharacterized protein" ID="ID_244937899" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC9A1: 1.19-fold Up; FDR = 0.126; PValue = 0.0463; mean CPM = 29.32; solute carrier family 9 (sodium/hydrogen exchanger), member 1" ID="ID_1126958287" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GPR68: 1.5-fold Down; FDR = 0.574; PValue = 0.311; mean CPM = 1.318; G protein-coupled receptor 68" ID="ID_963274338" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF11A: 1.4-fold Down; FDR = 0.676; PValue = 0.388; mean CPM = 0.9723; tumor necrosis factor receptor superfamily, member 11a, NFKB activator" ID="ID_714172829" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNB1: 1.79-fold Up; FDR = 0.731; PValue = 0.433; mean CPM = 0.8526; interferon, beta 1, fibroblast" ID="ID_325943805" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACP5: 1.16-fold Up; FDR = 0.924; PValue = 0.73; mean CPM = 0.9503; acid phosphatase 5, tartrate resistant" ID="ID_1920332970" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRPV5: 1.09-fold Down; FDR = 1; PValue = 0.969; mean CPM = 0.8655; transient receptor potential cation channel, subfamily V, member 5" ID="ID_1637809948" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Glutathione metabolism (WP100:Rev45319): FDR = 8.24e-10, PValue = 2.1e-10" ID="ID_1339102148" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="OPLAH: 4.24-fold Down; FDR = 4.67e-14; PValue = 5.59e-16; mean CPM = 15.18; 5-oxoprolinase (ATP-hydrolysing)" ID="ID_1449071740" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GCLM: 1.99-fold Up; FDR = 8.02e-08; PValue = 4.38e-09; mean CPM = 17.26; glutamate-cysteine ligase, modifier subunit" ID="ID_1206615900" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IDH1: 1.87-fold Up; FDR = 1.39e-07; PValue = 8.02e-09; mean CPM = 56.62; isocitrate dehydrogenase 1 (NADP+), soluble" ID="ID_1602838894" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ANPEP: 2.06-fold Down; FDR = 0.000149; PValue = 1.95e-05; mean CPM = 9.629; alanyl (membrane) aminopeptidase" ID="ID_1522355547" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GGT5: 1.54-fold Up; FDR = 0.00581; PValue = 0.00126; mean CPM = 42.83; gamma-glutamyltransferase 5" ID="ID_752460398" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GGT5: 1.49-fold Up; FDR = 0.0151; PValue = 0.00378; mean CPM = 6.923; gamma-glutamyltransferase 5" ID="ID_259474835" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSTT2B: 1.27-fold Up; FDR = 0.0194; PValue = 0.00509; mean CPM = 16.85; glutathione S-transferase theta 2B (gene/pseudogene)" ID="ID_965981166" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSR: 1.26-fold Up; FDR = 0.0263; PValue = 0.00721; mean CPM = 28.15; glutathione reductase" ID="ID_1116777242" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSS: 1.19-fold Down; FDR = 0.0461; PValue = 0.014; mean CPM = 57.28; glutathione synthetase" ID="ID_1627403716" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSTM1: 1.17-fold Down; FDR = 0.199; PValue = 0.0815; mean CPM = 19.09; glutathione S-transferase mu 1" ID="ID_576765152" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GCLC: 1.1-fold Up; FDR = 0.649; PValue = 0.367; mean CPM = 261.3; glutamate-cysteine ligase, catalytic subunit" ID="ID_256780817" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSTA1: 1.14-fold Down; FDR = 0.911; PValue = 0.697; mean CPM = 0.7880; glutathione S-transferase alpha 1" ID="ID_710601625" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSTT1: 1.04-fold Down; FDR = 1; PValue = 0.861; mean CPM = 2.560; glutathione S-transferase theta 1" ID="ID_1037278515" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Apoptosis Modulation by HSP70 (WP384:Rev41236): FDR = 1.39e-09, PValue = 3.61e-10" ID="ID_574844848" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_651679802" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSPA1B: 2.24-fold Down; FDR = 4.33e-09; PValue = 1.71e-10; mean CPM = 44.90; Heat shock 70 kDa protein 1A/1B (Heat shock 70 kDa protein 1/2)(HSP70.1/HSP70.2)(HSP70-1/HSP70-2)" ID="ID_672811826" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BID: 1.66-fold Up; FDR = 5.41e-09; PValue = 2.19e-10; mean CPM = 35.19; BH3 interacting domain death agonist" ID="ID_1981861681" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_1983924644" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_1700407321" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_604005090" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_1503845402" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_577124876" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FADD: 1.18-fold Down; FDR = 0.0936; PValue = 0.0324; mean CPM = 30.89; Uncharacterized protein" ID="ID_128153506" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP6: 1.17-fold Up; FDR = 0.197; PValue = 0.0807; mean CPM = 14.25; caspase 6, apoptosis-related cysteine peptidase" ID="ID_1977442337" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP7: 1.15-fold Up; FDR = 0.218; PValue = 0.0916; mean CPM = 21.49; caspase 7, apoptosis-related cysteine peptidase" ID="ID_1198032143" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000039103: 1.67-fold Down; FDR = 0.221; PValue = 0.0927; mean CPM = 1.310; Uncharacterized protein" ID="ID_1774240274" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AIFM1: 1.12-fold Down; FDR = 0.251; PValue = 0.109; mean CPM = 46.82; apoptosis-inducing factor, mitochondrion-associated, 1" ID="ID_1825320148" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1A: 1.11-fold Up; FDR = 0.297; PValue = 0.134; mean CPM = 134.7; tumor necrosis factor receptor superfamily, member 1A" ID="ID_790358481" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_1332625257" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APAF1: 1.05-fold Down; FDR = 0.837; PValue = 0.543; mean CPM = 32.11; apoptotic peptidase activating factor 1" ID="ID_837057128" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYCS: 1.05-fold Up; FDR = 0.854; PValue = 0.565; mean CPM = 93.43; cytochrome c, somatic" ID="ID_938388441" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000040219: 1.08-fold Up; FDR = 0.86; PValue = 0.575; mean CPM = 8.818; Uncharacterized protein" ID="ID_1982660415" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP2: 1.05-fold Up; FDR = 0.906; PValue = 0.667; mean CPM = 12.88; caspase 2, apoptosis-related cysteine peptidase" ID="ID_626419278" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000009289: 1.07-fold Up; FDR = 0.963; PValue = 0.798; mean CPM = 2.536; Uncharacterized protein" ID="ID_732620226" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP9: 1.01-fold Up; FDR = 1; PValue = 0.908; mean CPM = 19.86; caspase 9, apoptosis-related cysteine peptidase" ID="ID_703597519" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- </node>
- <node TEXT="GlobalAncova gene set test" ID="ID_1398670831" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="Proteasome Degradation (WP183:Rev45274): FDR = 3.58e-10, PValue = 2.73e-12" ID="ID_76331815" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="PSMB8: 15.4-fold Up; FDR = 1.64e-26; PValue = 5.69e-30; mean CPM = 246.0; proteasome subunit beta type-8 isoform E1 proprotein" ID="ID_78978072" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMB10: 13.4-fold Up; FDR = 5.15e-26; PValue = 2.42e-29; mean CPM = 202.9; Proteasome subunit beta type" ID="ID_28844191" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMB9: 18.6-fold Up; FDR = 5.15e-24; PValue = 5.86e-27; mean CPM = 380.3; proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)" ID="ID_850454193" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSME1: 5.25-fold Up; FDR = 7.8e-24; PValue = 9.53e-27; mean CPM = 157.6; Uncharacterized protein" ID="ID_342291817" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000027180: 6.97-fold Up; FDR = 1.24e-21; PValue = 3.39e-24; mean CPM = 285.4; Uncharacterized protein" ID="ID_460984723" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000027180: 6.97-fold Up; FDR = 1.24e-21; PValue = 3.39e-24; mean CPM = 285.4; Uncharacterized protein" ID="ID_1415243377" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000005183: 4.07-fold Up; FDR = 2.87e-21; PValue = 8.51e-24; mean CPM = 164.7; Uncharacterized protein" ID="ID_1732714560" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000005183: 4.07-fold Up; FDR = 2.87e-21; PValue = 8.51e-24; mean CPM = 164.7; Uncharacterized protein" ID="ID_782384561" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAMU-B: 6.07-fold Up; FDR = 2.71e-19; PValue = 1.2e-21; mean CPM = 2098; Uncharacterized protein" ID="ID_760944894" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMA6: 3.39-fold Up; FDR = 3.27e-19; PValue = 1.49e-21; mean CPM = 174.6; proteasome (prosome, macropain) subunit, alpha type, 6" ID="ID_247882728" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMA4: 2.69-fold Up; FDR = 1.03e-16; PValue = 8.26e-19; mean CPM = 125.7; proteasome (prosome, macropain) subunit, alpha type, 4" ID="ID_185670915" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="UBA7: 2.28-fold Up; FDR = 4.07e-15; PValue = 4.01e-17; mean CPM = 75.25; ubiquitin-like modifier activating enzyme 7" ID="ID_1277290427" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMA2: 1.94-fold Up; FDR = 8.77e-14; PValue = 1.15e-15; mean CPM = 126.0; proteasome (prosome, macropain) subunit, alpha type, 2" ID="ID_1713228777" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMA3: 1.97-fold Up; FDR = 2.59e-12; PValue = 4.66e-14; mean CPM = 94.63; proteasome (prosome, macropain) subunit, alpha type, 3" ID="ID_1339211306" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMA5: 1.71-fold Up; FDR = 2.64e-10; PValue = 7.81e-12; mean CPM = 103.0; proteasome (prosome, macropain) subunit, alpha type, 5" ID="ID_24787202" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMA1: 1.56-fold Up; FDR = 9.63e-09; PValue = 4.15e-10; mean CPM = 100.6; proteasome (prosome, macropain) subunit, alpha type, 1" ID="ID_362813260" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMB1: 1.54-fold Up; FDR = 3.38e-08; PValue = 1.68e-09; mean CPM = 193.0; proteasome (prosome, macropain) subunit, beta type, 1" ID="ID_633194756" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMD10: 1.44-fold Up; FDR = 0.000408; PValue = 6.1e-05; mean CPM = 18.47; proteasome (prosome, macropain) 26S subunit, non-ATPase, 10" ID="ID_1107036745" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMB7: 1.32-fold Up; FDR = 0.000758; PValue = 0.000123; mean CPM = 186.3; proteasome (prosome, macropain) subunit, beta type, 7" ID="ID_746131330" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMA7: 1.3-fold Up; FDR = 0.00111; PValue = 0.00019; mean CPM = 83.97; proteasome (prosome, macropain) subunit, alpha type, 7" ID="ID_931718694" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="H2AFX: 1.51-fold Down; FDR = 0.00139; PValue = 0.000246; mean CPM = 50.91; H2A histone family, member X" ID="ID_1541876775" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="UBE2D1: 1.53-fold Up; FDR = 0.00256; PValue = 0.000491; mean CPM = 9.796; ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)" ID="ID_104677654" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="UBA1: 1.29-fold Down; FDR = 0.00274; PValue = 0.000529; mean CPM = 454.0; ubiquitin-like modifier activating enzyme 1" ID="ID_327635286" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="UBE2D3: 1.26-fold Up; FDR = 0.00529; PValue = 0.00113; mean CPM = 129.0; Uncharacterized protein" ID="ID_1808095517" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMB2: 1.26-fold Up; FDR = 0.00539; PValue = 0.00116; mean CPM = 75.44; Proteasome subunit beta type" ID="ID_595423363" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMB4: 1.25-fold Up; FDR = 0.00737; PValue = 0.00165; mean CPM = 203.7; proteasome (prosome, macropain) subunit, beta type, 4" ID="ID_107497223" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMC6: 1.25-fold Up; FDR = 0.00969; PValue = 0.00227; mean CPM = 50.35; proteasome (prosome, macropain) 26S subunit, ATPase, 6" ID="ID_1250569238" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPN2: 1.24-fold Down; FDR = 0.0118; PValue = 0.00285; mean CPM = 392.4; ribophorin II" ID="ID_216362943" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMC2: 1.23-fold Up; FDR = 0.0127; PValue = 0.0031; mean CPM = 107.7; proteasome (prosome, macropain) 26S subunit, ATPase, 2" ID="ID_162925417" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="UBE2D2: 1.25-fold Up; FDR = 0.0128; PValue = 0.00312; mean CPM = 35.11; ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)" ID="ID_12800052" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="UBB: 1.22-fold Up; FDR = 0.0235; PValue = 0.00634; mean CPM = 526.7; ubiquitin B" ID="ID_965192447" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="H2AFZ: 1.3-fold Up; FDR = 0.0433; PValue = 0.013; mean CPM = 239.3; H2A histone family, member Z" ID="ID_1750482222" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPN1: 1.2-fold Down; FDR = 0.0443; PValue = 0.0133; mean CPM = 385.0; ribophorin I" ID="ID_654682550" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="UCHL1: 1.33-fold Up; FDR = 0.0578; PValue = 0.0183; mean CPM = 437.6; ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)" ID="ID_1408320124" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMD7: 1.18-fold Up; FDR = 0.0606; PValue = 0.0193; mean CPM = 90.67; proteasome (prosome, macropain) 26S subunit, non-ATPase, 7" ID="ID_706415463" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="UBE2B: 1.18-fold Up; FDR = 0.0712; PValue = 0.0234; mean CPM = 43.91; ubiquitin-conjugating enzyme E2B (RAD6 homolog)" ID="ID_692550671" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMD3: 1.17-fold Down; FDR = 0.0862; PValue = 0.0293; mean CPM = 144.8; proteasome (prosome, macropain) 26S subunit, non-ATPase, 3" ID="ID_618895835" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HIST1H2AB: 1.44-fold Down; FDR = 0.122; PValue = 0.0447; mean CPM = 27.61; histone cluster 1, H2ab" ID="ID_1906497476" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMD9: 1.15-fold Up; FDR = 0.129; PValue = 0.0476; mean CPM = 64.87; proteasome (prosome, macropain) 26S subunit, non-ATPase, 9" ID="ID_310353627" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMB6: 1.15-fold Up; FDR = 0.129; PValue = 0.0478; mean CPM = 142.5; Proteasome subunit beta type" ID="ID_258551707" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMC1: 1.14-fold Up; FDR = 0.154; PValue = 0.0595; mean CPM = 106.6; proteasome (prosome, macropain) 26S subunit, ATPase, 1" ID="ID_64326789" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMB3: 1.14-fold Up; FDR = 0.173; PValue = 0.0685; mean CPM = 101.4; proteasome (prosome, macropain) subunit, beta type, 3" ID="ID_1231577695" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMD12: 1.12-fold Up; FDR = 0.262; PValue = 0.115; mean CPM = 79.63; proteasome (prosome, macropain) 26S subunit, non-ATPase, 12" ID="ID_229209302" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMC5: 1.11-fold Down; FDR = 0.272; PValue = 0.12; mean CPM = 91.70; proteasome (prosome, macropain) 26S subunit, ATPase, 5" ID="ID_1106146797" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMC4: 1.11-fold Down; FDR = 0.283; PValue = 0.125; mean CPM = 92.37; proteasome (prosome, macropain) 26S subunit, ATPase, 4" ID="ID_123221386" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMC3: 1.11-fold Down; FDR = 0.301; PValue = 0.136; mean CPM = 165.0; proteasome (prosome, macropain) 26S subunit, ATPase, 3" ID="ID_500999712" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMD2: 1.11-fold Down; FDR = 0.343; PValue = 0.16; mean CPM = 262.0; proteasome (prosome, macropain) 26S subunit, non-ATPase, 2" ID="ID_1138769616" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMD6: 1.1-fold Up; FDR = 0.367; PValue = 0.174; mean CPM = 108.1; 26S proteasome non-ATPase regulatory subunit 6; Uncharacterized protein" ID="ID_495843773" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMD11: 1.08-fold Up; FDR = 0.501; PValue = 0.259; mean CPM = 87.50; proteasome (prosome, macropain) 26S subunit, non-ATPase, 11" ID="ID_1648088078" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMB5: 1.07-fold Down; FDR = 0.575; PValue = 0.312; mean CPM = 166.1; proteasome (prosome, macropain) subunit, beta type, 5" ID="ID_120044482" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000029957: 1.36-fold Down; FDR = 0.65; PValue = 0.368; mean CPM = 1.099; Uncharacterized protein" ID="ID_1522414904" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMD13: 1.04-fold Up; FDR = 0.86; PValue = 0.575; mean CPM = 149.8; proteasome (prosome, macropain) 26S subunit, non-ATPase, 13" ID="ID_1599761309" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMD5: 1.04-fold Up; FDR = 0.87; PValue = 0.587; mean CPM = 65.35; proteasome (prosome, macropain) 26S subunit, non-ATPase, 5" ID="ID_1656104712" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HIST1H2AE: 1.06-fold Down; FDR = 0.886; PValue = 0.607; mean CPM = 107.6; histone cluster 1, H2ae" ID="ID_649284513" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_1204162138" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMD8: 1.03-fold Down; FDR = 0.911; PValue = 0.695; mean CPM = 126.7; proteasome (prosome, macropain) 26S subunit, non-ATPase, 8" ID="ID_1651973829" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000039234: 1.28-fold Down; FDR = 0.963; PValue = 0.798; mean CPM = 0.8652; Uncharacterized protein" ID="ID_1252033727" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NEDD4: 1.01-fold Down; FDR = 1; PValue = 0.86; mean CPM = 49.99; neural precursor cell expressed, developmentally down-regulated 4" ID="ID_498593823" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSME3: No Change; FDR = 1; PValue = 0.946; mean CPM = 64.75; proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)" ID="ID_680582067" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Toll-like receptor signaling pathway (WP75:Rev45082): FDR = 3.58e-10, PValue = 8.21e-12" ID="ID_1546993607" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TLR2: 8.94-fold Up; FDR = 6.97e-23; PValue = 1.25e-25; mean CPM = 18.41; toll-like receptor 2" ID="ID_768738569" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL10: 462-fold Up; FDR = 1.01e-21; PValue = 2.65e-24; mean CPM = 286.2; Macaca mulatta chemokine (C-X-C motif) ligand 10 (CXCL10), mRNA." ID="ID_776942178" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR3: 10.3-fold Up; FDR = 1.95e-21; PValue = 5.6e-24; mean CPM = 35.70; toll-like receptor 3" ID="ID_15449573" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL11: 256-fold Up; FDR = 1e-19; PValue = 3.96e-22; mean CPM = 84.82; chemokine (C-X-C motif) ligand 11" ID="ID_1326838493" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL9: 345-fold Up; FDR = 4.16e-19; PValue = 1.97e-21; mean CPM = 175.7; Macaca mulatta chemokine (C-X-C motif) ligand 9 (CXCL9), mRNA." ID="ID_1713474138" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_556714750" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF7: 14.8-fold Up; FDR = 7.66e-18; PValue = 4.82e-20; mean CPM = 11.54; Macaca mulatta interferon regulatory factor 7 (IRF7), mRNA." ID="ID_618915726" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_1901982749" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LY96: 3.13-fold Up; FDR = 1.27e-10; PValue = 3.43e-12; mean CPM = 6.127; lymphocyte antigen 96" ID="ID_1923170674" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR4: 3.45-fold Up; FDR = 3.1e-09; PValue = 1.19e-10; mean CPM = 7.456; Macaca mulatta toll-like receptor 4 (TLR4), mRNA." ID="ID_298752506" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_427475757" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK4: 1.8-fold Up; FDR = 3.31e-08; PValue = 1.64e-09; mean CPM = 12.89; interleukin-1 receptor-associated kinase 4" ID="ID_1923169513" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1876089837" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL5: 6.74-fold Up; FDR = 2.65e-07; PValue = 1.64e-08; mean CPM = 30.35; chemokine (C-C motif) ligand 5" ID="ID_701340057" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_327147689" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD14: 2.75-fold Down; FDR = 6.54e-07; PValue = 4.46e-08; mean CPM = 5.195; CD14 molecule" ID="ID_1917751292" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_304094004" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_1217312002" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR2: 1.74-fold Up; FDR = 1.85e-06; PValue = 1.44e-07; mean CPM = 26.05; interferon (alpha, beta and omega) receptor 2" ID="ID_395870468" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_309832357" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K3: 1.45-fold Down; FDR = 7.01e-06; PValue = 6.34e-07; mean CPM = 180.1; mitogen-activated protein kinase kinase 3" ID="ID_1062179661" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_66282026" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPP1: 2.25-fold Down; FDR = 7.74e-05; PValue = 9.29e-06; mean CPM = 35.33; secreted phosphoprotein 1" ID="ID_375543331" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_767374943" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP2: 1.45-fold Up; FDR = 0.000179; PValue = 2.4e-05; mean CPM = 65.31; TGF-beta activated kinase 1/MAP3K7 binding protein 2" ID="ID_1157817708" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40: 2.76-fold Up; FDR = 0.00039; PValue = 5.79e-05; mean CPM = 9.139; CD40 molecule, TNF receptor superfamily member 5" ID="ID_1599192570" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TOLLIP: 1.36-fold Down; FDR = 0.000551; PValue = 8.57e-05; mean CPM = 28.79; Uncharacterized protein" ID="ID_1396915372" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBK1: 1.3-fold Up; FDR = 0.00337; PValue = 0.000674; mean CPM = 30.46; TANK-binding kinase 1" ID="ID_387578383" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1038930340" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_595067167" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR5: 1.86-fold Down; FDR = 0.00878; PValue = 0.00203; mean CPM = 3.008; toll-like receptor 5" ID="ID_1325888011" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12A: 2.09-fold Up; FDR = 0.00924; PValue = 0.00215; mean CPM = 2.872; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)" ID="ID_698197211" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR1: 1.27-fold Up; FDR = 0.0101; PValue = 0.00237; mean CPM = 82.39; Uncharacterized protein" ID="ID_596734390" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1220929680" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL8: 2.33-fold Up; FDR = 0.0209; PValue = 0.00552; mean CPM = 2326; interleukin 8" ID="ID_1486040226" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_200675082" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_944489457" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1276804018" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL3: 2.04-fold Down; FDR = 0.067; PValue = 0.0218; mean CPM = 3.575; chemokine (C-C motif) ligand 3" ID="ID_1913936411" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K8: 1.35-fold Down; FDR = 0.0831; PValue = 0.0281; mean CPM = 8.912; mitogen-activated protein kinase kinase kinase 8" ID="ID_1179329980" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FADD: 1.18-fold Down; FDR = 0.0936; PValue = 0.0324; mean CPM = 30.89; Uncharacterized protein" ID="ID_1470421905" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_1707075191" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_1984674957" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1047676621" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_1814872162" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_722435563" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP1: 1.12-fold Down; FDR = 0.351; PValue = 0.165; mean CPM = 17.96; TGF-beta activated kinase 1/MAP3K7 binding protein 1" ID="ID_910155560" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1718266746" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TICAM1: 1.11-fold Down; FDR = 0.398; PValue = 0.192; mean CPM = 26.73; toll-like receptor adaptor molecule 1" ID="ID_171714439" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_470471117" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1234582015" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK12: 1.19-fold Down; FDR = 0.422; PValue = 0.208; mean CPM = 6.569; mitogen-activated protein kinase 12" ID="ID_1900702634" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1417139136" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_577992010" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK13: 1.22-fold Down; FDR = 0.536; PValue = 0.284; mean CPM = 3.100; mitogen-activated protein kinase 13" ID="ID_1491728547" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LBP: 1.52-fold Down; FDR = 0.591; PValue = 0.324; mean CPM = 0.8819; lipopolysaccharide binding protein" ID="ID_311912832" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF3: 1.07-fold Up; FDR = 0.611; PValue = 0.338; mean CPM = 34.56; TNF receptor-associated factor 3" ID="ID_518655638" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_87511521" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNB1: 1.79-fold Up; FDR = 0.731; PValue = 0.433; mean CPM = 0.8526; interferon, beta 1, fibroblast" ID="ID_229778448" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMED7-TICAM2: 1.05-fold Down; FDR = 0.796; PValue = 0.493; mean CPM = 150.6; TMED7-TICAM2 readthrough" ID="ID_283265569" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA6: 1.41-fold Down; FDR = 0.807; PValue = 0.504; mean CPM = 0.8019; interferon, alpha 6" ID="ID_305923685" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR6: 1.07-fold Down; FDR = 0.84; PValue = 0.546; mean CPM = 7.909; toll-like receptor 6" ID="ID_53854215" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TIRAP: 1.07-fold Up; FDR = 0.841; PValue = 0.548; mean CPM = 8.693; Macaca mulatta toll-interleukin 1 receptor (TIR) domain containing adaptor protein (TIRAP), mRNA." ID="ID_1421198127" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF5: 1.06-fold Down; FDR = 0.85; PValue = 0.561; mean CPM = 9.280; interferon regulatory factor 5" ID="ID_378590581" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_528086049" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1810051975" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR7: 1.37-fold Down; FDR = 0.878; PValue = 0.597; mean CPM = 0.8402; toll-like receptor 7" ID="ID_1607716452" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK1: 1.04-fold Down; FDR = 0.885; PValue = 0.606; mean CPM = 41.54; interleukin-1 receptor-associated kinase 1" ID="ID_931118101" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_352298217" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA13: 1.13-fold Up; FDR = 0.908; PValue = 0.677; mean CPM = 0.7960; interferon, alpha 13" ID="ID_1927749882" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA8: 1.13-fold Down; FDR = 0.911; PValue = 0.702; mean CPM = 0.7910; interferon, alpha 8" ID="ID_859051391" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKE: 1.03-fold Up; FDR = 0.929; PValue = 0.737; mean CPM = 21.61; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon" ID="ID_251727455" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA14: 1.22-fold Up; FDR = 0.965; PValue = 0.802; mean CPM = 0.8654; interferon, alpha 14" ID="ID_1358329112" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_367054135" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD80: 1.08-fold Up; FDR = 0.971; PValue = 0.812; mean CPM = 1.157; CD80 molecule" ID="ID_929250748" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_85970357" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA4: 1.28-fold Down; FDR = 0.983; PValue = 0.829; mean CPM = 0.8584; interferon, alpha 4" ID="ID_809784889" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12B: 1.07-fold Up; FDR = 0.983; PValue = 0.831; mean CPM = 0.8197; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)" ID="ID_1189789863" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_575334398" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR9: 1.01-fold Down; FDR = 1; PValue = 0.859; mean CPM = 21.45; Macaca mulatta toll-like receptor 9 (TLR9), mRNA." ID="ID_1422698767" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR1: 1.02-fold Up; FDR = 1; PValue = 0.945; mean CPM = 1.221; toll-like receptor 1" ID="ID_1861763493" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD86: 1.01-fold Down; FDR = 1; PValue = 0.99; mean CPM = 0.8012; CD86 molecule" ID="ID_96934801" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA1: No Change; FDR = 1; PValue = 0.998; mean CPM = 0.8014; interferon, alpha 1" ID="ID_583175764" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="EPO Receptor Signaling (WP581:Rev41162): FDR = 3.58e-10, PValue = 8.67e-12" ID="ID_1795976546" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_310612865" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_373387654" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5A: 2.28-fold Up; FDR = 6.87e-14; PValue = 8.58e-16; mean CPM = 21.55; signal transducer and activator of transcription 5A" ID="ID_1933706747" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_502081834" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPRU: 2.57-fold Down; FDR = 1.5e-09; PValue = 5.3e-11; mean CPM = 17.80; Uncharacterized protein" ID="ID_875745071" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_32284216" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRS1: 2.78-fold Up; FDR = 7.67e-09; PValue = 3.19e-10; mean CPM = 26.55; Uncharacterized protein" ID="ID_1577926865" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_933905545" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1590670396" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPRC: 6.08-fold Up; FDR = 0.000285; PValue = 4.07e-05; mean CPM = 1.220; protein tyrosine phosphatase, receptor type, C" ID="ID_510688354" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CISH: 1.95-fold Up; FDR = 0.00116; PValue = 0.0002; mean CPM = 5.083; cytokine inducible SH2-containing protein" ID="ID_812973738" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EPOR: 1.56-fold Down; FDR = 0.014; PValue = 0.00347; mean CPM = 3.898; erythropoietin receptor" ID="ID_1050753813" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_554865307" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1744585371" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1017514419" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_1202861559" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_925327114" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EPO: 1.77-fold Up; FDR = 0.39; PValue = 0.188; mean CPM = 0.9174; Macaca mulatta erythropoietin (EPO), mRNA." ID="ID_1921917406" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1470605808" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_39530266" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASA1: 1.03-fold Down; FDR = 0.909; PValue = 0.69; mean CPM = 103.7; Ras GTPase-activating protein 1 isoform 1; Uncharacterized protein" ID="ID_1489343083" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_1728614851" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Regulation of toll-like receptor signaling pathway (WP1449:Rev45049): FDR = 3.58e-10, PValue = 8.79e-12" ID="ID_1346108863" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TLR2: 8.94-fold Up; FDR = 6.97e-23; PValue = 1.25e-25; mean CPM = 18.41; toll-like receptor 2" ID="ID_1394931484" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL10: 462-fold Up; FDR = 1.01e-21; PValue = 2.65e-24; mean CPM = 286.2; Macaca mulatta chemokine (C-X-C motif) ligand 10 (CXCL10), mRNA." ID="ID_59902828" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR3: 10.3-fold Up; FDR = 1.95e-21; PValue = 5.6e-24; mean CPM = 35.70; toll-like receptor 3" ID="ID_933172074" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL11: 256-fold Up; FDR = 1e-19; PValue = 3.96e-22; mean CPM = 84.82; chemokine (C-X-C motif) ligand 11" ID="ID_88732232" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RBCK1: 2.19-fold Up; FDR = 2.7e-19; PValue = 1.18e-21; mean CPM = 118.3; RanBP-type and C3HC4-type zinc finger containing 1" ID="ID_587884878" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL9: 345-fold Up; FDR = 4.16e-19; PValue = 1.97e-21; mean CPM = 175.7; Macaca mulatta chemokine (C-X-C motif) ligand 9 (CXCL9), mRNA." ID="ID_1739657490" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1041113491" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF7: 14.8-fold Up; FDR = 7.66e-18; PValue = 4.82e-20; mean CPM = 11.54; Macaca mulatta interferon regulatory factor 7 (IRF7), mRNA." ID="ID_1428951232" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_710103869" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAFD1: 2.07-fold Up; FDR = 4.13e-13; PValue = 6.18e-15; mean CPM = 152.6; TRAF-type zinc finger domain containing 1" ID="ID_1706775731" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LY96: 3.13-fold Up; FDR = 1.27e-10; PValue = 3.43e-12; mean CPM = 6.127; lymphocyte antigen 96" ID="ID_1806037691" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR4: 3.45-fold Up; FDR = 3.1e-09; PValue = 1.19e-10; mean CPM = 7.456; Macaca mulatta toll-like receptor 4 (TLR4), mRNA." ID="ID_1496538345" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PELI1: 2-fold Up; FDR = 5.5e-09; PValue = 2.23e-10; mean CPM = 30.48; pellino homolog 1 (Drosophila)" ID="ID_137691328" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NEU1: 1.73-fold Down; FDR = 5.89e-09; PValue = 2.4e-10; mean CPM = 44.30; Sialidase-1 Precursor (EC 3.2.1.18)(Lysosomal sialidase)(N-acetyl-alpha-neuraminidase 1)(Acetylneuraminyl hydrolase)(G9 sialidase)" ID="ID_405952160" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_1572739678" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK4: 1.8-fold Up; FDR = 3.31e-08; PValue = 1.64e-09; mean CPM = 12.89; interleukin-1 receptor-associated kinase 4" ID="ID_936746629" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_450906146" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL5: 6.74-fold Up; FDR = 2.65e-07; PValue = 1.64e-08; mean CPM = 30.35; chemokine (C-C motif) ligand 5" ID="ID_1816570159" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_480291623" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD14: 2.75-fold Down; FDR = 6.54e-07; PValue = 4.46e-08; mean CPM = 5.195; CD14 molecule" ID="ID_1346059077" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYLD: 1.46-fold Up; FDR = 1.36e-06; PValue = 1.01e-07; mean CPM = 77.47; cylindromatosis (turban tumor syndrome)" ID="ID_286935146" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_403461421" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_148168348" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR2: 1.74-fold Up; FDR = 1.85e-06; PValue = 1.44e-07; mean CPM = 26.05; interferon (alpha, beta and omega) receptor 2" ID="ID_1958983730" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1912129979" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TREM1: 5.53-fold Down; FDR = 4.59e-06; PValue = 3.91e-07; mean CPM = 22.68; triggering receptor expressed on myeloid cells 1" ID="ID_1337883633" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K3: 1.45-fold Down; FDR = 7.01e-06; PValue = 6.34e-07; mean CPM = 180.1; mitogen-activated protein kinase kinase 3" ID="ID_1698336880" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1892091995" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFAIP3: 1.79-fold Up; FDR = 3.14e-05; PValue = 3.34e-06; mean CPM = 52.47; tumor necrosis factor, alpha-induced protein 3" ID="ID_675010501" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLK1: 2.25-fold Down; FDR = 3.23e-05; PValue = 3.46e-06; mean CPM = 27.29; polo-like kinase 1 (Drosophila)" ID="ID_182894486" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPP1: 2.25-fold Down; FDR = 7.74e-05; PValue = 9.29e-06; mean CPM = 35.33; secreted phosphoprotein 1" ID="ID_138551178" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_446968082" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTNNAL1: 1.4-fold Down; FDR = 0.000133; PValue = 1.7e-05; mean CPM = 134.1; catenin (cadherin-associated protein), alpha-like 1" ID="ID_902645829" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP2: 1.45-fold Up; FDR = 0.000179; PValue = 2.4e-05; mean CPM = 65.31; TGF-beta activated kinase 1/MAP3K7 binding protein 2" ID="ID_1347278322" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP3: 1.5-fold Up; FDR = 0.000276; PValue = 3.92e-05; mean CPM = 11.67; TGF-beta activated kinase 1/MAP3K7 binding protein 3" ID="ID_1245501785" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40: 2.76-fold Up; FDR = 0.00039; PValue = 5.79e-05; mean CPM = 9.139; CD40 molecule, TNF receptor superfamily member 5" ID="ID_669468057" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TOLLIP: 1.36-fold Down; FDR = 0.000551; PValue = 8.57e-05; mean CPM = 28.79; Uncharacterized protein" ID="ID_561448627" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CISH: 1.95-fold Up; FDR = 0.00116; PValue = 0.0002; mean CPM = 5.083; cytokine inducible SH2-containing protein" ID="ID_819407479" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBK1: 1.3-fold Up; FDR = 0.00337; PValue = 0.000674; mean CPM = 30.46; TANK-binding kinase 1" ID="ID_208882800" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RNF216: 1.26-fold Down; FDR = 0.00452; PValue = 0.000946; mean CPM = 59.60; ring finger protein 216" ID="ID_415129914" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_378791900" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_109990773" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK3: 1.54-fold Up; FDR = 0.00653; PValue = 0.00144; mean CPM = 19.97; interleukin-1 receptor-associated kinase 3" ID="ID_1629078175" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR5: 1.86-fold Down; FDR = 0.00878; PValue = 0.00203; mean CPM = 3.008; toll-like receptor 5" ID="ID_275306153" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12A: 2.09-fold Up; FDR = 0.00924; PValue = 0.00215; mean CPM = 2.872; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)" ID="ID_1423559328" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNAR1: 1.27-fold Up; FDR = 0.0101; PValue = 0.00237; mean CPM = 82.39; Uncharacterized protein" ID="ID_890014024" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SARM1: 1.69-fold Up; FDR = 0.0194; PValue = 0.00509; mean CPM = 5.456; sterile alpha and TIR motif containing 1" ID="ID_864666896" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PELI2: 1.41-fold Down; FDR = 0.0196; PValue = 0.00515; mean CPM = 6.598; pellino homolog 2 (Drosophila)" ID="ID_959561448" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1078948765" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL8: 2.33-fold Up; FDR = 0.0209; PValue = 0.00552; mean CPM = 2326; interleukin 8" ID="ID_1654075643" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_23648162" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_331593045" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1065186618" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RNF31: 1.19-fold Up; FDR = 0.0502; PValue = 0.0154; mean CPM = 52.31; ring finger protein 31" ID="ID_61957992" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL3: 2.04-fold Down; FDR = 0.067; PValue = 0.0218; mean CPM = 3.575; chemokine (C-C motif) ligand 3" ID="ID_737135452" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K8: 1.35-fold Down; FDR = 0.0831; PValue = 0.0281; mean CPM = 8.912; mitogen-activated protein kinase kinase kinase 8" ID="ID_195286452" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="OTUD5: 1.16-fold Down; FDR = 0.0921; PValue = 0.0318; mean CPM = 54.00; OTU domain containing 5" ID="ID_1116114473" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FADD: 1.18-fold Down; FDR = 0.0936; PValue = 0.0324; mean CPM = 30.89; Uncharacterized protein" ID="ID_557648530" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RNF41: 1.17-fold Down; FDR = 0.0994; PValue = 0.0348; mean CPM = 33.28; ring finger protein 41" ID="ID_760911294" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_1323046431" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_1932537356" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_882687650" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CUEDC2: 1.13-fold Up; FDR = 0.188; PValue = 0.0762; mean CPM = 58.93; CUE domain containing 2" ID="ID_1179978548" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK2: 1.27-fold Down; FDR = 0.259; PValue = 0.113; mean CPM = 10.13; interleukin-1 receptor-associated kinase 2" ID="ID_299963785" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FBXW5: 1.12-fold Down; FDR = 0.263; PValue = 0.115; mean CPM = 70.62; Uncharacterized protein" ID="ID_679698996" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_1992755325" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SQSTM1: 1.19-fold Down; FDR = 0.289; PValue = 0.129; mean CPM = 270.1; sequestosome 1" ID="ID_1694207652" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_732990596" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP1: 1.12-fold Down; FDR = 0.351; PValue = 0.165; mean CPM = 17.96; TGF-beta activated kinase 1/MAP3K7 binding protein 1" ID="ID_1608660990" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PELI3: 1.17-fold Down; FDR = 0.381; PValue = 0.182; mean CPM = 8.442; pellino homolog 3 (Drosophila)" ID="ID_1210443814" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_1127354655" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TICAM1: 1.11-fold Down; FDR = 0.398; PValue = 0.192; mean CPM = 26.73; toll-like receptor adaptor molecule 1" ID="ID_1222927988" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_880966613" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1101239507" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK12: 1.19-fold Down; FDR = 0.422; PValue = 0.208; mean CPM = 6.569; mitogen-activated protein kinase 12" ID="ID_556065565" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SIGIRR: 1.29-fold Up; FDR = 0.437; PValue = 0.217; mean CPM = 2.330; single immunoglobulin and toll-interleukin 1 receptor (TIR) domain" ID="ID_1810035249" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_798955771" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_1408500150" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK13: 1.22-fold Down; FDR = 0.536; PValue = 0.284; mean CPM = 3.100; mitogen-activated protein kinase 13" ID="ID_1387089206" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LBP: 1.52-fold Down; FDR = 0.591; PValue = 0.324; mean CPM = 0.8819; lipopolysaccharide binding protein" ID="ID_1168448482" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF3: 1.07-fold Up; FDR = 0.611; PValue = 0.338; mean CPM = 34.56; TNF receptor-associated factor 3" ID="ID_174677969" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZMYND11: 1.06-fold Up; FDR = 0.655; PValue = 0.371; mean CPM = 72.68; zinc finger, MYND domain containing 11" ID="ID_687490016" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_1447740067" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNB1: 1.79-fold Up; FDR = 0.731; PValue = 0.433; mean CPM = 0.8526; interferon, beta 1, fibroblast" ID="ID_805301510" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMED7-TICAM2: 1.05-fold Down; FDR = 0.796; PValue = 0.493; mean CPM = 150.6; TMED7-TICAM2 readthrough" ID="ID_642973592" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA6: 1.41-fold Down; FDR = 0.807; PValue = 0.504; mean CPM = 0.8019; interferon, alpha 6" ID="ID_1136375768" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR6: 1.07-fold Down; FDR = 0.84; PValue = 0.546; mean CPM = 7.909; toll-like receptor 6" ID="ID_984110073" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TIRAP: 1.07-fold Up; FDR = 0.841; PValue = 0.548; mean CPM = 8.693; Macaca mulatta toll-interleukin 1 receptor (TIR) domain containing adaptor protein (TIRAP), mRNA." ID="ID_1444922111" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SFTPA1: 1.39-fold Down; FDR = 0.845; PValue = 0.554; mean CPM = 0.8018; Pulmonary surfactant-associated protein A" ID="ID_577523887" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SFTPA1: 1.39-fold Down; FDR = 0.845; PValue = 0.554; mean CPM = 0.8018; Pulmonary surfactant-associated protein A" ID="ID_696072554" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF5: 1.06-fold Down; FDR = 0.85; PValue = 0.561; mean CPM = 9.280; interferon regulatory factor 5" ID="ID_668246421" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MBL2: 1.3-fold Up; FDR = 0.85; PValue = 0.561; mean CPM = 0.7954; mannose-binding lectin (protein C) 2, soluble (opsonic defect)" ID="ID_1881251262" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1449829872" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD180: 1.69-fold Down; FDR = 0.868; PValue = 0.585; mean CPM = 0.8488; CD180 molecule" ID="ID_1367132060" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_107806453" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR7: 1.37-fold Down; FDR = 0.878; PValue = 0.597; mean CPM = 0.8402; toll-like receptor 7" ID="ID_742201482" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRAK1: 1.04-fold Down; FDR = 0.885; PValue = 0.606; mean CPM = 41.54; interleukin-1 receptor-associated kinase 1" ID="ID_291676598" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_857219205" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SFTPA1: 1.19-fold Up; FDR = 0.903; PValue = 0.645; mean CPM = 0.7982; surfactant protein A1" ID="ID_1447968085" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA13: 1.13-fold Up; FDR = 0.908; PValue = 0.677; mean CPM = 0.7960; interferon, alpha 13" ID="ID_169468454" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA8: 1.13-fold Down; FDR = 0.911; PValue = 0.702; mean CPM = 0.7910; interferon, alpha 8" ID="ID_278868377" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKE: 1.03-fold Up; FDR = 0.929; PValue = 0.737; mean CPM = 21.61; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon" ID="ID_911688415" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA14: 1.22-fold Up; FDR = 0.965; PValue = 0.802; mean CPM = 0.8654; interferon, alpha 14" ID="ID_79069717" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_309752180" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD80: 1.08-fold Up; FDR = 0.971; PValue = 0.812; mean CPM = 1.157; CD80 molecule" ID="ID_799813440" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_310874990" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA4: 1.28-fold Down; FDR = 0.983; PValue = 0.829; mean CPM = 0.8584; interferon, alpha 4" ID="ID_27881693" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL12B: 1.07-fold Up; FDR = 0.983; PValue = 0.831; mean CPM = 0.8197; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)" ID="ID_1140883956" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_1288764506" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR9: 1.01-fold Down; FDR = 1; PValue = 0.859; mean CPM = 21.45; Macaca mulatta toll-like receptor 9 (TLR9), mRNA." ID="ID_1571008266" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLR1: 1.02-fold Up; FDR = 1; PValue = 0.945; mean CPM = 1.221; toll-like receptor 1" ID="ID_1662096858" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BTK: No Change; FDR = 1; PValue = 0.965; mean CPM = 0.8336; Bruton agammaglobulinemia tyrosine kinase" ID="ID_1054776795" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SYK: 1.11-fold Up; FDR = 1; PValue = 0.977; mean CPM = 0.8420; spleen tyrosine kinase" ID="ID_1084992424" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SFTPD: 1.03-fold Down; FDR = 1; PValue = 0.982; mean CPM = 0.8042; surfactant protein D" ID="ID_1491211083" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD86: 1.01-fold Down; FDR = 1; PValue = 0.99; mean CPM = 0.8012; CD86 molecule" ID="ID_297726501" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNA1: No Change; FDR = 1; PValue = 0.998; mean CPM = 0.8014; interferon, alpha 1" ID="ID_92925900" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Type II interferon signaling (IFNG) (WP619:Rev45027): FDR = 3.58e-10, PValue = 9.33e-12" ID="ID_1356097841" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="TAP1: 8.86-fold Up; FDR = 4.25e-27; PValue = 3.99e-31; mean CPM = 524.4; Antigen peptide transporter 1 (APT1)(Peptide transporter TAP1)(ATP-binding cassette sub-family B member 2)(Peptide supply factor 1)(Peptide transporter PSF1)(PSF-1)(Peptide transporter involved in antigen processing 1)(Really interesting new gene 4 /.../n)" ID="ID_1799269445" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GBP1: 54.9-fold Up; FDR = 3.11e-24; PValue = 2.93e-27; mean CPM = 1282; guanylate binding protein 1, interferon-inducible, 67kDa" ID="ID_571553333" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSMB9: 18.6-fold Up; FDR = 5.15e-24; PValue = 5.86e-27; mean CPM = 380.3; proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)" ID="ID_385479577" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFI6: 19-fold Up; FDR = 6.4e-22; PValue = 1.59e-24; mean CPM = 1370; interferon, alpha-inducible protein 6" ID="ID_1525404206" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFIT2: 80.8-fold Up; FDR = 9.69e-22; PValue = 2.5e-24; mean CPM = 473.4; interferon-induced protein with tetratricopeptide repeats 2" ID="ID_1342572235" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL10: 462-fold Up; FDR = 1.01e-21; PValue = 2.65e-24; mean CPM = 286.2; Macaca mulatta chemokine (C-X-C motif) ligand 10 (CXCL10), mRNA." ID="ID_558977609" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000027180: 6.97-fold Up; FDR = 1.24e-21; PValue = 3.39e-24; mean CPM = 285.4; Uncharacterized protein" ID="ID_1659050124" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF1: 18.6-fold Up; FDR = 1.53e-21; PValue = 4.24e-24; mean CPM = 240.7; interferon regulatory factor 1" ID="ID_1600609904" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000005183: 4.07-fold Up; FDR = 2.87e-21; PValue = 8.51e-24; mean CPM = 164.7; Uncharacterized protein" ID="ID_933945116" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="OAS1: 41-fold Up; FDR = 1.01e-20; PValue = 3.28e-23; mean CPM = 37.38; Macaca mulatta 2',5'-oligoadenylate synthetase 1, 40/46kDa (OAS1), mRNA." ID="ID_129862805" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF9: 3.85-fold Up; FDR = 2.6e-19; PValue = 1.12e-21; mean CPM = 106.4; interferon regulatory factor 9" ID="ID_726550101" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL9: 345-fold Up; FDR = 4.16e-19; PValue = 1.97e-21; mean CPM = 175.7; Macaca mulatta chemokine (C-X-C motif) ligand 9 (CXCL9), mRNA." ID="ID_1870669390" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT2: 2.67-fold Up; FDR = 8.02e-19; PValue = 4.03e-21; mean CPM = 185.6; signal transducer and activator of transcription 2, 113kDa" ID="ID_1996887628" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_1150896449" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1726440587" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF2: 3.25-fold Up; FDR = 2.61e-18; PValue = 1.48e-20; mean CPM = 32.37; interferon regulatory factor 2" ID="ID_1494319341" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2AK2: 3.01-fold Up; FDR = 6.08e-18; PValue = 3.74e-20; mean CPM = 47.85; eukaryotic translation initiation factor 2-alpha kinase 2" ID="ID_1111516708" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CIITA: 45.8-fold Up; FDR = 1.14e-17; PValue = 7.44e-20; mean CPM = 27.80; class II, major histocompatibility complex, transactivator" ID="ID_849774054" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICAM1: 24.6-fold Up; FDR = 2.39e-17; PValue = 1.64e-19; mean CPM = 232.4; intercellular adhesion molecule 1" ID="ID_748504554" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ISG15: 15.5-fold Up; FDR = 2.16e-15; PValue = 2.02e-17; mean CPM = 55.60; ISG15 ubiquitin-like modifier" ID="ID_1644045648" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF8: 11.4-fold Up; FDR = 6e-09; PValue = 2.46e-10; mean CPM = 5.558; interferon regulatory factor 8" ID="ID_487605318" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS3: 1.69-fold Up; FDR = 0.000994; PValue = 0.000167; mean CPM = 37.76; suppressor of cytokine signaling 3" ID="ID_1541937926" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR1: 1.31-fold Up; FDR = 0.00151; PValue = 0.000268; mean CPM = 37.77; interferon gamma receptor 1" ID="ID_1017324863" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HIST1H4F: 1.68-fold Up; FDR = 0.0162; PValue = 0.00411; mean CPM = 53.41; histone cluster 1, H4f" ID="ID_502764904" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNGR2: 1.23-fold Up; FDR = 0.0258; PValue = 0.00707; mean CPM = 46.52; interferon gamma receptor 2 (interferon gamma transducer 1)" ID="ID_114055980" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HIST1H4K: 1.36-fold Down; FDR = 0.0491; PValue = 0.015; mean CPM = 23.81; Histone H4" ID="ID_511688573" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_1458923394" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF4: 2.95-fold Down; FDR = 0.124; PValue = 0.0456; mean CPM = 0.9773; interferon regulatory factor 4" ID="ID_1211765436" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HIST1H4H: 1.22-fold Up; FDR = 0.156; PValue = 0.0604; mean CPM = 205.4; histone cluster 1, H4h" ID="ID_1434732961" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HIST1H4C: 1.33-fold Down; FDR = 0.204; PValue = 0.0842; mean CPM = 188.3; histone cluster 1, H4c" ID="ID_332578030" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HIST1H4L: 1.43-fold Down; FDR = 0.211; PValue = 0.0877; mean CPM = 23.77; histone cluster 1, H4l" ID="ID_1372845331" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HIST4H4: 1.23-fold Down; FDR = 0.234; PValue = 0.0995; mean CPM = 130.3; histone cluster 4, H4" ID="ID_1873896304" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_370492104" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HIST1H4D: 1.2-fold Down; FDR = 0.655; PValue = 0.371; mean CPM = 77.97; histone cluster 1, H4d" ID="ID_1276263299" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_200274716" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCD: 1.06-fold Up; FDR = 0.696; PValue = 0.404; mean CPM = 37.45; protein kinase C, delta" ID="ID_1605504081" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYBB: 1.52-fold Up; FDR = 0.705; PValue = 0.412; mean CPM = 0.9872; cytochrome b-245, beta polypeptide" ID="ID_1719046167" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNB1: 1.79-fold Up; FDR = 0.731; PValue = 0.433; mean CPM = 0.8526; interferon, beta 1, fibroblast" ID="ID_244149324" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HIST1H4B: 1.09-fold Up; FDR = 0.804; PValue = 0.5; mean CPM = 159.3; histone cluster 1, H4b" ID="ID_315286522" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HIST2H4B: 1.09-fold Down; FDR = 0.849; PValue = 0.559; mean CPM = 390.8; histone cluster 2, H4b" ID="ID_1661237130" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_963248562" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HIST1H4K: 1.07-fold Down; FDR = 0.909; PValue = 0.685; mean CPM = 58.36; histone cluster 1, H4k" ID="ID_178148867" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOS2: 1.4-fold Down; FDR = 0.917; PValue = 0.718; mean CPM = 0.8546; nitric oxide synthase 2, inducible" ID="ID_970346367" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPI1: 1.12-fold Down; FDR = 0.935; PValue = 0.747; mean CPM = 1.030; spleen focus forming virus (SFFV) proviral integration oncogene spi1" ID="ID_950498955" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="REG1A: No Change; FDR = 1; PValue = 1; mean CPM = 0.7990; regenerating islet-derived 1 alpha" ID="ID_106317733" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="REG1A: No Change; FDR = 1; PValue = 1; mean CPM = 0.7825; Uncharacterized protein" ID="ID_1900277442" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HIST1H4A: No Change; FDR = 1; PValue = 1; mean CPM = 0.7841; histone cluster 1, H4a" ID="ID_4104127" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-2 Signaling pathway (WP49:Rev45366): FDR = 3.85e-10, PValue = 1.41e-11" ID="ID_1673904133" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="NMI: 6.35-fold Up; FDR = 1.04e-21; PValue = 2.78e-24; mean CPM = 42.95; N-myc (and STAT) interactor" ID="ID_1239114942" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_8314581" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5A: 2.28-fold Up; FDR = 6.87e-14; PValue = 8.58e-16; mean CPM = 21.55; signal transducer and activator of transcription 5A" ID="ID_1946861687" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_723389457" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_969225477" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2B: 3.54-fold Up; FDR = 1.24e-07; PValue = 7.07e-09; mean CPM = 5.971; PTK2B protein tyrosine kinase 2 beta" ID="ID_1256087210" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_798362395" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1429573744" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPT: 2.89-fold Down; FDR = 3.14e-05; PValue = 3.34e-06; mean CPM = 2.105; microtubule-associated protein tau" ID="ID_184918490" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB2: 1.38-fold Down; FDR = 4.66e-05; PValue = 5.24e-06; mean CPM = 61.90; ribosomal protein S6 kinase, 70kDa, polypeptide 2" ID="ID_1641005541" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS3: 1.69-fold Up; FDR = 0.000994; PValue = 0.000167; mean CPM = 37.76; suppressor of cytokine signaling 3" ID="ID_620276091" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CISH: 1.95-fold Up; FDR = 0.00116; PValue = 0.0002; mean CPM = 5.083; cytokine inducible SH2-containing protein" ID="ID_1831255789" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK3: 2.31-fold Up; FDR = 0.00186; PValue = 0.000342; mean CPM = 2.154; Janus kinase 3" ID="ID_1855611280" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GAB2: 1.33-fold Down; FDR = 0.00208; PValue = 0.000387; mean CPM = 22.59; GRB2-associated binding protein 2" ID="ID_1472936209" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FYN: 1.22-fold Up; FDR = 0.0156; PValue = 0.00393; mean CPM = 92.94; FYN oncogene related to SRC, FGR, YES" ID="ID_1406814175" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1770430795" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1436202864" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_1131747561" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_1763082955" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_478577916" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_1282055282" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1602317357" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1194426150" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_1442590453" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND2: 1.2-fold Up; FDR = 0.335; PValue = 0.155; mean CPM = 76.91; cyclin D2" ID="ID_183335756" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRKL: 1.11-fold Up; FDR = 0.371; PValue = 0.176; mean CPM = 34.10; v-crk sarcoma virus CT10 oncogene homolog (avian)-like" ID="ID_1567891255" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2: 1.48-fold Up; FDR = 0.384; PValue = 0.184; mean CPM = 1.344; Uncharacterized protein" ID="ID_1577480614" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_733507585" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_612417307" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOXO3: 1.08-fold Down; FDR = 0.55; PValue = 0.294; mean CPM = 48.45; forkhead box O3" ID="ID_1050612626" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6: 1.08-fold Up; FDR = 0.584; PValue = 0.318; mean CPM = 892.5; ribosomal protein S6" ID="ID_1367888388" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CBL: 1.05-fold Down; FDR = 0.824; PValue = 0.524; mean CPM = 51.06; Cas-Br-M (murine) ecotropic retroviral transforming sequence" ID="ID_1661040280" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1400244707" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB1: 1.04-fold Up; FDR = 0.88; PValue = 0.6; mean CPM = 30.80; Uncharacterized protein" ID="ID_641997510" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2RA: 1.08-fold Up; FDR = 0.945; PValue = 0.766; mean CPM = 0.8493; interleukin 2 receptor, alpha" ID="ID_126418142" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_402222399" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SYK: 1.11-fold Up; FDR = 1; PValue = 0.977; mean CPM = 0.8420; spleen tyrosine kinase" ID="ID_1143914199" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2: 1.03-fold Up; FDR = 1; PValue = 0.998; mean CPM = 0.7974; interleukin 2" ID="ID_1999640055" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-6 signaling pathway (WP364:Rev44848): FDR = 3.85e-10, PValue = 1.52e-11" ID="ID_201099106" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="IRF1: 18.6-fold Up; FDR = 1.53e-21; PValue = 4.24e-24; mean CPM = 240.7; interferon regulatory factor 1" ID="ID_969207146" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_1527335134" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1404017975" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_1244032989" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_599578431" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL6ST: 1.78-fold Up; FDR = 1.86e-08; PValue = 8.65e-10; mean CPM = 437.6; interleukin 6 signal transducer (gp130, oncostatin M receptor)" ID="ID_254683637" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRDM1: 3.05-fold Up; FDR = 3.55e-08; PValue = 1.78e-09; mean CPM = 8.715; PR domain containing 1, with ZNF domain" ID="ID_1082909780" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_941672547" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L1: 1.51-fold Up; FDR = 9.13e-07; PValue = 6.52e-08; mean CPM = 66.15; Bcl-2-like protein 1; Bcl-2-like protein 1 isoform 1; Uncharacterized protein" ID="ID_1585916490" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_24796381" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL6R: 3.84-fold Down; FDR = 6.68e-05; PValue = 7.89e-06; mean CPM = 4.840; interleukin 6 receptor" ID="ID_1770952260" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAD: 1.36-fold Down; FDR = 0.000605; PValue = 9.52e-05; mean CPM = 48.46; BCL2-associated agonist of cell death" ID="ID_820122878" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS3: 1.69-fold Up; FDR = 0.000994; PValue = 0.000167; mean CPM = 37.76; suppressor of cytokine signaling 3" ID="ID_304279250" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYK2: 1.24-fold Down; FDR = 0.0142; PValue = 0.00354; mean CPM = 42.58; tyrosine kinase 2" ID="ID_383444338" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC1: 1.25-fold Up; FDR = 0.0159; PValue = 0.00403; mean CPM = 27.51; histone deacetylase 1" ID="ID_1685550750" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1771844330" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_569979765" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_1829222924" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCOA1: 1.18-fold Up; FDR = 0.112; PValue = 0.04; mean CPM = 20.42; nuclear receptor coactivator 1" ID="ID_492454777" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_806032587" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="A2M: 1.33-fold Up; FDR = 0.181; PValue = 0.0726; mean CPM = 750.0; alpha-2-macroglobulin" ID="ID_1995567604" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1479625084" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_1883587429" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1146294556" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_794609183" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCD: 1.06-fold Up; FDR = 0.696; PValue = 0.404; mean CPM = 37.45; protein kinase C, delta" ID="ID_977302202" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HCK: 1.3-fold Down; FDR = 0.797; PValue = 0.494; mean CPM = 0.9272; Uncharacterized protein" ID="ID_1045699201" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV1: 1.25-fold Down; FDR = 0.858; PValue = 0.572; mean CPM = 0.9515; vav 1 guanine nucleotide exchange factor" ID="ID_1763243416" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1168078457" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB1: 1.04-fold Up; FDR = 0.88; PValue = 0.6; mean CPM = 30.80; Uncharacterized protein" ID="ID_712339843" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_1080144536" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREBBP: 1.01-fold Down; FDR = 0.993; PValue = 0.847; mean CPM = 137.7; CREB binding protein" ID="ID_360529171" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_1214635031" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLK: No Change; FDR = 1; PValue = 0.97; mean CPM = 11.78; nemo-like kinase" ID="ID_1359771765" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AGT: 1.02-fold Down; FDR = 1; PValue = 0.996; mean CPM = 0.8004; angiotensinogen (serpin peptidase inhibitor, clade A, member 8)" ID="ID_1126867297" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRP: No Change; FDR = 1; PValue = 1; mean CPM = 0.7818; Uncharacterized protein" ID="ID_1255110641" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Fatty Acid Biosynthesis (WP357:Rev45261): FDR = 3.85e-10, PValue = 1.6e-11" ID="ID_1986441003" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="ACSL1: 6.98-fold Up; FDR = 1.75e-21; PValue = 4.92e-24; mean CPM = 194.6; acyl-CoA synthetase long-chain family member 1" ID="ID_1672326494" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACSL5: 8.65-fold Up; FDR = 4.07e-18; PValue = 2.39e-20; mean CPM = 34.19; acyl-CoA synthetase long-chain family member 5" ID="ID_461453573" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PC: 2.94-fold Down; FDR = 2.05e-12; PValue = 3.55e-14; mean CPM = 48.99; pyruvate carboxylase" ID="ID_789448289" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DECR1: 1.83-fold Up; FDR = 2.91e-10; PValue = 8.64e-12; mean CPM = 54.00; 2,4-dienoyl-CoA reductase, mitochondrial; Uncharacterized protein" ID="ID_281805170" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FASN: 2.14-fold Down; FDR = 1.36e-09; PValue = 4.74e-11; mean CPM = 192.4; fatty acid synthase" ID="ID_1219432509" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ECHDC1: 1.64-fold Up; FDR = 3.51e-07; PValue = 2.24e-08; mean CPM = 36.83; enoyl CoA hydratase domain containing 1" ID="ID_1000314003" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACSL4: 1.44-fold Up; FDR = 2.98e-05; PValue = 3.15e-06; mean CPM = 126.3; acyl-CoA synthetase long-chain family member 4" ID="ID_400140683" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACACA: 1.27-fold Down; FDR = 0.00395; PValue = 0.000809; mean CPM = 54.13; acetyl-CoA carboxylase alpha" ID="ID_6830183" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PECR: 1.44-fold Up; FDR = 0.00406; PValue = 0.000836; mean CPM = 12.33; peroxisomal trans-2-enoyl-CoA reductase" ID="ID_1639136204" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SCD: 1.92-fold Down; FDR = 0.0103; PValue = 0.00244; mean CPM = 11.46; stearoyl-CoA desaturase (delta-9-desaturase)" ID="ID_3461288" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACSL6: 2.32-fold Down; FDR = 0.0551; PValue = 0.0173; mean CPM = 1.472; acyl-CoA synthetase long-chain family member 6" ID="ID_575075448" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000024909: 1.17-fold Down; FDR = 0.0796; PValue = 0.0267; mean CPM = 110.7; Uncharacterized protein" ID="ID_612350330" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ECH1: 1.14-fold Up; FDR = 0.182; PValue = 0.0729; mean CPM = 60.46; enoyl CoA hydratase 1, peroxisomal" ID="ID_1875034433" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACAA2: 1.13-fold Up; FDR = 0.198; PValue = 0.0811; mean CPM = 42.36; acetyl-CoA acyltransferase 2" ID="ID_1476725908" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MECR: 1.13-fold Down; FDR = 0.363; PValue = 0.172; mean CPM = 13.95; mitochondrial trans-2-enoyl-CoA reductase" ID="ID_1157027879" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HADH: 1.1-fold Up; FDR = 0.419; PValue = 0.205; mean CPM = 32.14; hydroxyacyl-CoA dehydrogenase" ID="ID_1269257948" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACSS2: 1.05-fold Down; FDR = 0.773; PValue = 0.471; mean CPM = 38.17; Uncharacterized protein" ID="ID_342356657" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACSL3: 1.05-fold Up; FDR = 0.787; PValue = 0.484; mean CPM = 61.21; acyl-CoA synthetase long-chain family member 3" ID="ID_599140481" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ECHDC3: 1.07-fold Up; FDR = 0.813; PValue = 0.51; mean CPM = 10.66; Uncharacterized protein" ID="ID_1663917905" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACLY: 1.02-fold Down; FDR = 0.928; PValue = 0.737; mean CPM = 42.39; ATP citrate lyase; Uncharacterized protein" ID="ID_780802257" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ECHS1: 1.01-fold Up; FDR = 1; PValue = 0.885; mean CPM = 49.79; enoyl CoA hydratase, short chain, 1, mitochondrial" ID="ID_272336813" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-7 signaling pathway (WP205:Rev45369): FDR = 4.45e-10, PValue = 2.09e-11" ID="ID_1489280506" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_48343180" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5A: 2.28-fold Up; FDR = 6.87e-14; PValue = 8.58e-16; mean CPM = 21.55; signal transducer and activator of transcription 5A" ID="ID_1929578039" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL7: 9.03-fold Up; FDR = 1.39e-13; PValue = 1.9e-15; mean CPM = 5.288; interleukin 7" ID="ID_401057413" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_1812505087" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1B: 1.64-fold Up; FDR = 1.22e-08; PValue = 5.39e-10; mean CPM = 32.96; Cyclin-dependent kinase inhibitor 1B; Uncharacterized protein" ID="ID_564605609" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2B: 3.54-fold Up; FDR = 1.24e-07; PValue = 7.07e-09; mean CPM = 5.971; PTK2B protein tyrosine kinase 2 beta" ID="ID_640001092" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1745373038" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L1: 1.51-fold Up; FDR = 9.13e-07; PValue = 6.52e-08; mean CPM = 66.15; Bcl-2-like protein 1; Bcl-2-like protein 1 isoform 1; Uncharacterized protein" ID="ID_1133624468" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_325038168" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1735433858" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAD: 1.36-fold Down; FDR = 0.000605; PValue = 9.52e-05; mean CPM = 48.46; BCL2-associated agonist of cell death" ID="ID_1394562554" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK3: 2.31-fold Up; FDR = 0.00186; PValue = 0.000342; mean CPM = 2.154; Janus kinase 3" ID="ID_784167497" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FYN: 1.22-fold Up; FDR = 0.0156; PValue = 0.00393; mean CPM = 92.94; FYN oncogene related to SRC, FGR, YES" ID="ID_678999145" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_80492456" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_307936357" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_342889779" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL7R: 1.76-fold Down; FDR = 0.0698; PValue = 0.0229; mean CPM = 3.067; interleukin 7 receptor" ID="ID_1105634970" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_310634904" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND1: 1.17-fold Up; FDR = 0.121; PValue = 0.0443; mean CPM = 867.3; cyclin D1" ID="ID_768907695" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_801641351" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1330937270" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1130891095" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2RA: 1.08-fold Up; FDR = 0.945; PValue = 0.766; mean CPM = 0.8493; interleukin 2 receptor, alpha" ID="ID_1199088088" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Fatty Acid Beta Oxidation (WP143:Rev45258): FDR = 5.55e-10, PValue = 3.08e-11" ID="ID_565597667" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="ACSL1: 6.98-fold Up; FDR = 1.75e-21; PValue = 4.92e-24; mean CPM = 194.6; acyl-CoA synthetase long-chain family member 1" ID="ID_1774331097" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACSL5: 8.65-fold Up; FDR = 4.07e-18; PValue = 2.39e-20; mean CPM = 34.19; acyl-CoA synthetase long-chain family member 5" ID="ID_1798188248" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GPD2: 2.11-fold Up; FDR = 1.4e-14; PValue = 1.58e-16; mean CPM = 142.3; glycerol-3-phosphate dehydrogenase 2 (mitochondrial)" ID="ID_1779639688" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DECR1: 1.83-fold Up; FDR = 2.91e-10; PValue = 8.64e-12; mean CPM = 54.00; 2,4-dienoyl-CoA reductase, mitochondrial; Uncharacterized protein" ID="ID_182586156" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HADHB: 1.43-fold Up; FDR = 4.95e-06; PValue = 4.25e-07; mean CPM = 117.7; hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit" ID="ID_295629239" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACSL4: 1.44-fold Up; FDR = 2.98e-05; PValue = 3.15e-06; mean CPM = 126.3; acyl-CoA synthetase long-chain family member 4" ID="ID_611206532" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACADL: 1.59-fold Up; FDR = 0.0017; PValue = 0.00031; mean CPM = 6.176; acyl-CoA dehydrogenase, long chain" ID="ID_334038275" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CPT2: 1.33-fold Down; FDR = 0.00216; PValue = 0.000405; mean CPM = 22.86; carnitine palmitoyltransferase 2" ID="ID_474713233" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACAT1: 1.35-fold Down; FDR = 0.00247; PValue = 0.000471; mean CPM = 32.72; acetyl-CoA acetyltransferase 1" ID="ID_1030050897" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CPT1A: 1.38-fold Down; FDR = 0.00434; PValue = 0.000903; mean CPM = 110.4; carnitine palmitoyltransferase 1A (liver)" ID="ID_876968552" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GCDH: 1.32-fold Down; FDR = 0.00538; PValue = 0.00115; mean CPM = 17.15; glutaryl-CoA dehydrogenase" ID="ID_1999636344" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ECI1: 1.27-fold Down; FDR = 0.021; PValue = 0.00556; mean CPM = 16.80; enoyl-CoA delta isomerase 1" ID="ID_1294861326" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACSL6: 2.32-fold Down; FDR = 0.0551; PValue = 0.0173; mean CPM = 1.472; acyl-CoA synthetase long-chain family member 6" ID="ID_1109362771" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LIPE: 1.27-fold Down; FDR = 0.0669; PValue = 0.0217; mean CPM = 9.982; lipase, hormone-sensitive" ID="ID_1294242189" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DLD: 1.16-fold Up; FDR = 0.12; PValue = 0.0435; mean CPM = 57.77; dihydrolipoamide dehydrogenase" ID="ID_1361648870" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HADH: 1.1-fold Up; FDR = 0.419; PValue = 0.205; mean CPM = 32.14; hydroxyacyl-CoA dehydrogenase" ID="ID_941472010" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LIPC: 1.39-fold Up; FDR = 0.676; PValue = 0.388; mean CPM = 0.9915; lipase, hepatic" ID="ID_1400881677" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TPI1: 1.07-fold Down; FDR = 0.681; PValue = 0.391; mean CPM = 521.3; triosephosphate isomerase 1" ID="ID_335261797" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HADHA: 1.06-fold Down; FDR = 0.721; PValue = 0.424; mean CPM = 170.9; hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit" ID="ID_193762475" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000004177: 1.07-fold Up; FDR = 0.768; PValue = 0.466; mean CPM = 15.82; Uncharacterized protein" ID="ID_39011617" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACSS2: 1.05-fold Down; FDR = 0.773; PValue = 0.471; mean CPM = 38.17; Uncharacterized protein" ID="ID_1864626444" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC25A20: 1.06-fold Up; FDR = 0.778; PValue = 0.475; mean CPM = 18.03; solute carrier family 25 (carnitine/acylcarnitine translocase), member 20" ID="ID_518165345" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACSL3: 1.05-fold Up; FDR = 0.787; PValue = 0.484; mean CPM = 61.21; acyl-CoA synthetase long-chain family member 3" ID="ID_581890731" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRAT: 1.04-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 64.03; carnitine O-acetyltransferase" ID="ID_1603670780" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PNPLA2: 1.03-fold Down; FDR = 0.903; PValue = 0.643; mean CPM = 52.84; patatin-like phospholipase domain containing 2" ID="ID_700764756" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CPT1B: 1.05-fold Up; FDR = 0.923; PValue = 0.728; mean CPM = 5.764; carnitine palmitoyltransferase 1B (muscle)" ID="ID_905669792" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TPI1: 1.02-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 133.1; triosephosphate isomerase 1" ID="ID_1111862553" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LPL: 1.08-fold Down; FDR = 1; PValue = 0.868; mean CPM = 0.9050; lipoprotein lipase" ID="ID_918333787" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ECHS1: 1.01-fold Up; FDR = 1; PValue = 0.885; mean CPM = 49.79; enoyl CoA hydratase, short chain, 1, mitochondrial" ID="ID_1594993725" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACADS: 1.01-fold Up; FDR = 1; PValue = 0.928; mean CPM = 17.72; acyl-CoA dehydrogenase, C-2 to C-3 short chain" ID="ID_1472183233" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GK2: 1.12-fold Down; FDR = 1; PValue = 0.972; mean CPM = 0.8255; glycerol kinase 2" ID="ID_899529957" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LIPF: 1.02-fold Down; FDR = 1; PValue = 0.985; mean CPM = 0.8334; lipase, gastric" ID="ID_158707175" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Mitochondrial LC-Fatty Acid Beta-Oxidation (WP368:Rev45141): FDR = 5.55e-10, PValue = 3.18e-11" ID="ID_1011454169" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="ACSL1: 6.98-fold Up; FDR = 1.75e-21; PValue = 4.92e-24; mean CPM = 194.6; acyl-CoA synthetase long-chain family member 1" ID="ID_856328898" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACSL4: 1.44-fold Up; FDR = 2.98e-05; PValue = 3.15e-06; mean CPM = 126.3; acyl-CoA synthetase long-chain family member 4" ID="ID_725769717" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SCP2: 1.34-fold Up; FDR = 0.000258; PValue = 3.65e-05; mean CPM = 107.5; sterol carrier protein 2" ID="ID_1939442780" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACADL: 1.59-fold Up; FDR = 0.0017; PValue = 0.00031; mean CPM = 6.176; acyl-CoA dehydrogenase, long chain" ID="ID_1017171072" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CPT2: 1.33-fold Down; FDR = 0.00216; PValue = 0.000405; mean CPM = 22.86; carnitine palmitoyltransferase 2" ID="ID_1811047123" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PECR: 1.44-fold Up; FDR = 0.00406; PValue = 0.000836; mean CPM = 12.33; peroxisomal trans-2-enoyl-CoA reductase" ID="ID_1447389926" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CPT1A: 1.38-fold Down; FDR = 0.00434; PValue = 0.000903; mean CPM = 110.4; carnitine palmitoyltransferase 1A (liver)" ID="ID_834901824" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EHHADH: 1.35-fold Up; FDR = 0.0132; PValue = 0.00323; mean CPM = 11.95; enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase" ID="ID_985337606" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ECI1: 1.27-fold Down; FDR = 0.021; PValue = 0.00556; mean CPM = 16.80; enoyl-CoA delta isomerase 1" ID="ID_600193265" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HADH: 1.1-fold Up; FDR = 0.419; PValue = 0.205; mean CPM = 32.14; hydroxyacyl-CoA dehydrogenase" ID="ID_712321194" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HADHA: 1.06-fold Down; FDR = 0.721; PValue = 0.424; mean CPM = 170.9; hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit" ID="ID_1591877431" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC25A20: 1.06-fold Up; FDR = 0.778; PValue = 0.475; mean CPM = 18.03; solute carrier family 25 (carnitine/acylcarnitine translocase), member 20" ID="ID_1574316227" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACSL3: 1.05-fold Up; FDR = 0.787; PValue = 0.484; mean CPM = 61.21; acyl-CoA synthetase long-chain family member 3" ID="ID_1258629019" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACADS: 1.01-fold Up; FDR = 1; PValue = 0.928; mean CPM = 17.72; acyl-CoA dehydrogenase, C-2 to C-3 short chain" ID="ID_1940891603" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Complement and Coagulation Cascades (WP558:Rev45058): FDR = 5.73e-10, PValue = 3.58e-11" ID="ID_272629132" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="SERPING1: 17.2-fold Up; FDR = 2.79e-22; PValue = 6.42e-25; mean CPM = 499.3; serpin peptidase inhibitor, clade G (C1 inhibitor), member 1" ID="ID_751350651" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C2: 4.8-fold Up; FDR = 3.21e-17; PValue = 2.26e-19; mean CPM = 200.3; Uncharacterized protein" ID="ID_791950839" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="F3: 5.59-fold Down; FDR = 3.39e-11; PValue = 8.05e-13; mean CPM = 79.22; coagulation factor III (thromboplastin, tissue factor)" ID="ID_1268645688" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLAU: 3.37-fold Down; FDR = 1.56e-10; PValue = 4.33e-12; mean CPM = 18.78; plasminogen activator, urokinase" ID="ID_479980866" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C3: 5.35-fold Up; FDR = 5.79e-07; PValue = 3.91e-08; mean CPM = 19.68; complement component 3" ID="ID_1138589073" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C3AR1: 4.66-fold Up; FDR = 1e-06; PValue = 7.26e-08; mean CPM = 15.65; complement component 3a receptor 1" ID="ID_772725989" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C5AR1: 3.36-fold Up; FDR = 3.05e-05; PValue = 3.23e-06; mean CPM = 14.55; complement component 5a receptor 1" ID="ID_1521284431" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SERPINE1: 1.58-fold Down; FDR = 0.00232; PValue = 0.000438; mean CPM = 5294; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1" ID="ID_946140036" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SERPINF2: 1.59-fold Up; FDR = 0.00264; PValue = 0.000509; mean CPM = 24.23; serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2" ID="ID_817671678" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="F12: 2.67-fold Down; FDR = 0.00473; PValue = 0.000996; mean CPM = 1.586; coagulation factor XII (Hageman factor)" ID="ID_1654852771" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PROS1: 1.31-fold Up; FDR = 0.0206; PValue = 0.00545; mean CPM = 20.23; protein S (alpha)" ID="ID_820826244" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="F8: 1.86-fold Up; FDR = 0.0276; PValue = 0.00765; mean CPM = 1.839; coagulation factor VIII, procoagulant component" ID="ID_1584726383" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLAT: 1.37-fold Down; FDR = 0.034; PValue = 0.00976; mean CPM = 76.44; plasminogen activator, tissue" ID="ID_1983606464" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SERPIND1: 2.04-fold Down; FDR = 0.046; PValue = 0.0139; mean CPM = 1.843; serpin peptidase inhibitor, clade D (heparin cofactor), member 1" ID="ID_1089085147" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C1QB: 2.62-fold Up; FDR = 0.0887; PValue = 0.0304; mean CPM = 1.092; complement component 1, q subcomponent, B chain" ID="ID_982232311" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="F2: 1.67-fold Down; FDR = 0.132; PValue = 0.0494; mean CPM = 1.475; coagulation factor II (thrombin)" ID="ID_106365732" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SERPINA1: 1.42-fold Up; FDR = 0.139; PValue = 0.0524; mean CPM = 32.29; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1" ID="ID_1968200081" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VWF: 1.42-fold Down; FDR = 0.174; PValue = 0.069; mean CPM = 24.05; von Willebrand factor" ID="ID_1983352532" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="A2M: 1.33-fold Up; FDR = 0.181; PValue = 0.0726; mean CPM = 750.0; alpha-2-macroglobulin" ID="ID_205048614" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLAUR: 1.19-fold Down; FDR = 0.199; PValue = 0.0819; mean CPM = 46.31; Uncharacterized protein" ID="ID_1170686555" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C1QC: 2.02-fold Up; FDR = 0.203; PValue = 0.0839; mean CPM = 1.322; complement component 1, q subcomponent, C chain" ID="ID_729544482" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD46: 1.13-fold Down; FDR = 0.214; PValue = 0.0894; mean CPM = 70.85; Uncharacterized protein" ID="ID_575458271" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CR1: 1.99-fold Up; FDR = 0.225; PValue = 0.095; mean CPM = 0.9520; Uncharacterized protein" ID="ID_736066274" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MASP1: 1.46-fold Down; FDR = 0.264; PValue = 0.115; mean CPM = 4.467; mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)" ID="ID_216677764" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SERPINC1: 1.74-fold Down; FDR = 0.398; PValue = 0.193; mean CPM = 0.9122; antithrombin-III" ID="ID_380667925" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SERPINA5: 1.57-fold Down; FDR = 0.409; PValue = 0.199; mean CPM = 1.235; plasma serine protease inhibitor" ID="ID_472307048" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="F2R: 1.1-fold Up; FDR = 0.458; PValue = 0.23; mean CPM = 35.05; coagulation factor II (thrombin) receptor" ID="ID_900001162" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C9: 1.41-fold Up; FDR = 0.505; PValue = 0.262; mean CPM = 1.295; complement component 9" ID="ID_144529834" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MASP2: 1.23-fold Down; FDR = 0.546; PValue = 0.291; mean CPM = 3.073; mannan-binding lectin serine peptidase 2" ID="ID_1225647283" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BDKRB1: 1.18-fold Up; FDR = 0.556; PValue = 0.298; mean CPM = 22.68; bradykinin receptor B1" ID="ID_1958551212" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TFPI: 1.09-fold Down; FDR = 0.606; PValue = 0.335; mean CPM = 64.96; tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)" ID="ID_1323583825" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CPB2: 1.43-fold Up; FDR = 0.695; PValue = 0.403; mean CPM = 0.9275; carboxypeptidase B2 (plasma)" ID="ID_191508995" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KNG1: 1.76-fold Up; FDR = 0.746; PValue = 0.447; mean CPM = 0.8419; Uncharacterized protein" ID="ID_1777769678" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="F9: 1.57-fold Down; FDR = 0.788; PValue = 0.485; mean CPM = 0.8079; coagulation factor IX" ID="ID_427964491" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGB: 1.44-fold Down; FDR = 0.797; PValue = 0.494; mean CPM = 0.8074; fibrinogen beta chain" ID="ID_1545043988" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C6: 1.72-fold Down; FDR = 0.856; PValue = 0.57; mean CPM = 0.8334; complement component 6" ID="ID_1234960350" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="F10: 1.07-fold Down; FDR = 0.91; PValue = 0.693; mean CPM = 2.929; coagulation factor X" ID="ID_248400393" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="F7: 1.07-fold Down; FDR = 0.921; PValue = 0.723; mean CPM = 2.252; coagulation factor VII (serum prothrombin conversion accelerator)" ID="ID_98268882" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLG: 1.41-fold Down; FDR = 0.937; PValue = 0.751; mean CPM = 0.8390; plasminogen" ID="ID_984850660" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="F13B: 1.15-fold Up; FDR = 0.942; PValue = 0.759; mean CPM = 0.8085; coagulation factor XIII, B polypeptide" ID="ID_1450426492" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C8G: 1.15-fold Up; FDR = 0.978; PValue = 0.822; mean CPM = 0.8664; complement component 8, gamma polypeptide" ID="ID_1428654500" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APOA2: 1.13-fold Down; FDR = 0.993; PValue = 0.847; mean CPM = 0.8139; apolipoprotein A-II" ID="ID_549387563" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C7: 1.11-fold Up; FDR = 1; PValue = 0.883; mean CPM = 0.8197; complement component 7" ID="ID_545686313" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THBD: 1.03-fold Up; FDR = 1; PValue = 0.943; mean CPM = 2.929; thrombomodulin" ID="ID_639803017" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CR2: 1.07-fold Down; FDR = 1; PValue = 0.997; mean CPM = 0.8253; complement component (3d/Epstein Barr virus) receptor 2" ID="ID_1033798007" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Prolactin Signaling Pathway (WP2037:Rev45275): FDR = 6.38e-10, PValue = 4.32e-11" ID="ID_709346210" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="IRF1: 18.6-fold Up; FDR = 1.53e-21; PValue = 4.24e-24; mean CPM = 240.7; interferon regulatory factor 1" ID="ID_1799930339" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_1938241845" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_592019962" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5A: 2.28-fold Up; FDR = 6.87e-14; PValue = 8.58e-16; mean CPM = 21.55; signal transducer and activator of transcription 5A" ID="ID_1289667988" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_1927604492" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIAS3: 1.63-fold Down; FDR = 2.24e-10; PValue = 6.51e-12; mean CPM = 53.00; protein inhibitor of activated STAT, 3" ID="ID_228197107" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_795899777" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRS1: 2.78-fold Up; FDR = 7.67e-09; PValue = 3.19e-10; mean CPM = 26.55; Uncharacterized protein" ID="ID_1747001270" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FLNA: 2.35-fold Down; FDR = 2.01e-08; PValue = 9.45e-10; mean CPM = 7159; filamin A, alpha" ID="ID_1155585818" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1891537358" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_1314192517" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_169707775" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1642362016" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1198742371" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_1935671068" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPIB: 1.45-fold Down; FDR = 8.64e-06; PValue = 8.03e-07; mean CPM = 806.4; peptidylprolyl isomerase B (cyclophilin B)" ID="ID_1518350387" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_799605780" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTSD: 1.65-fold Down; FDR = 0.000162; PValue = 2.13e-05; mean CPM = 578.9; cathepsin D" ID="ID_834074239" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS3: 1.69-fold Up; FDR = 0.000994; PValue = 0.000167; mean CPM = 37.76; suppressor of cytokine signaling 3" ID="ID_963291149" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CISH: 1.95-fold Up; FDR = 0.00116; PValue = 0.0002; mean CPM = 5.083; cytokine inducible SH2-containing protein" ID="ID_1003383723" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTOR: 1.3-fold Down; FDR = 0.00117; PValue = 0.000201; mean CPM = 107.5; mechanistic target of rapamycin (serine/threonine kinase)" ID="ID_1922145365" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GAB2: 1.33-fold Down; FDR = 0.00208; PValue = 0.000387; mean CPM = 22.59; GRB2-associated binding protein 2" ID="ID_361393650" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_161885193" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FYN: 1.22-fold Up; FDR = 0.0156; PValue = 0.00393; mean CPM = 92.94; FYN oncogene related to SRC, FGR, YES" ID="ID_323484513" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS2: 1.31-fold Down; FDR = 0.0188; PValue = 0.0049; mean CPM = 35.29; suppressor of cytokine signaling 2" ID="ID_690176860" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1808694565" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1684558101" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_1241664963" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_556105883" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN1: 1.2-fold Down; FDR = 0.0495; PValue = 0.0152; mean CPM = 35.05; protein tyrosine phosphatase, non-receptor type 1" ID="ID_1254984495" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_791420112" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_71067026" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF4EBP1: 1.23-fold Up; FDR = 0.0729; PValue = 0.0241; mean CPM = 40.55; eukaryotic translation initiation factor 4E binding protein 1" ID="ID_1801721070" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TEC: 1.65-fold Up; FDR = 0.0729; PValue = 0.0241; mean CPM = 3.190; tec protein tyrosine kinase" ID="ID_576562982" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB1: 1.23-fold Up; FDR = 0.0759; PValue = 0.0253; mean CPM = 2700; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)" ID="ID_847954015" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_1517717221" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AGAP2: 1.55-fold Up; FDR = 0.106; PValue = 0.0377; mean CPM = 2.136; ArfGAP with GTPase domain, ankyrin repeat and PH domain 2" ID="ID_1261002217" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_547822517" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_1592042665" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_985900311" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="YWHAG: 1.14-fold Down; FDR = 0.162; PValue = 0.0632; mean CPM = 175.7; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide" ID="ID_1048842006" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_482851275" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_539929300" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ERBB2: 1.14-fold Down; FDR = 0.23; PValue = 0.0977; mean CPM = 119.0; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)" ID="ID_1634392077" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_1849707524" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_536882468" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2: 1.1-fold Up; FDR = 0.394; PValue = 0.191; mean CPM = 102.5; PTK2 protein tyrosine kinase 2" ID="ID_1022546881" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1510520059" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_129170444" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_1535930576" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6: 1.08-fold Up; FDR = 0.584; PValue = 0.318; mean CPM = 892.5; ribosomal protein S6" ID="ID_1114976009" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_1689423619" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NEK3: 1.1-fold Up; FDR = 0.77; PValue = 0.468; mean CPM = 5.147; NIMA-related kinase 3" ID="ID_544226326" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="YWHAZ: 1.05-fold Down; FDR = 0.785; PValue = 0.482; mean CPM = 341.0; 14-3-3 protein zeta/delta; Uncharacterized protein" ID="ID_432389683" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CBL: 1.05-fold Down; FDR = 0.824; PValue = 0.524; mean CPM = 51.06; Cas-Br-M (murine) ecotropic retroviral transforming sequence" ID="ID_1052404439" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV1: 1.25-fold Down; FDR = 0.858; PValue = 0.572; mean CPM = 0.9515; vav 1 guanine nucleotide exchange factor" ID="ID_955749131" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZAP70: 1.25-fold Down; FDR = 0.872; PValue = 0.59; mean CPM = 0.8996; zeta-chain (TCR) associated protein kinase 70kDa" ID="ID_1533880870" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_433145695" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB1: 1.04-fold Up; FDR = 0.88; PValue = 0.6; mean CPM = 30.80; Uncharacterized protein" ID="ID_1214156457" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="YWHAZ: 1.09-fold Up; FDR = 0.888; PValue = 0.61; mean CPM = 3.241; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide" ID="ID_721920704" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK1: 1.03-fold Down; FDR = 0.911; PValue = 0.705; mean CPM = 18.65; p21 protein (Cdc42/Rac)-activated kinase 1" ID="ID_1237824060" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOS2: 1.4-fold Down; FDR = 0.917; PValue = 0.718; mean CPM = 0.8546; nitric oxide synthase 2, inducible" ID="ID_1418037247" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_86766651" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_1514991582" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRLR: 1.06-fold Down; FDR = 1; PValue = 0.889; mean CPM = 1.017; prolactin receptor" ID="ID_683580447" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_540187632" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV2: No Change; FDR = 1; PValue = 0.976; mean CPM = 25.65; vav 2 guanine nucleotide exchange factor" ID="ID_572706324" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Tryptophan metabolism (WP465:Rev45056): FDR = 1.3e-09, PValue = 9.47e-11" ID="ID_1631791384" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="WARS: 18.8-fold Up; FDR = 1.64e-26; PValue = 6.18e-30; mean CPM = 1926; Uncharacterized protein" ID="ID_374724776" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ALDH3A2: 2.28-fold Up; FDR = 3.87e-11; PValue = 9.34e-13; mean CPM = 141.3; aldehyde dehydrogenase 3 family, member A2" ID="ID_1932292817" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAT: 1.75-fold Up; FDR = 1.21e-09; PValue = 4.14e-11; mean CPM = 42.72; catalase" ID="ID_1392352863" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYP7B1: 2.51-fold Up; FDR = 7.19e-07; PValue = 4.96e-08; mean CPM = 4.335; cytochrome P450, family 7, subfamily B, polypeptide 1" ID="ID_174309328" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DHCR24: 4.93-fold Down; FDR = 1.5e-06; PValue = 1.12e-07; mean CPM = 2.190; 24-dehydrocholesterol reductase" ID="ID_813558985" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TDO2: 5.53-fold Down; FDR = 9.15e-06; PValue = 8.53e-07; mean CPM = 1.291; tryptophan 2,3-dioxygenase" ID="ID_135323666" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ALDH9A1: 1.39-fold Up; FDR = 3.68e-05; PValue = 4e-06; mean CPM = 71.34; aldehyde dehydrogenase 9 family, member A1" ID="ID_166251876" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ALDH2: 1.44-fold Down; FDR = 5.61e-05; PValue = 6.45e-06; mean CPM = 99.09; aldehyde dehydrogenase 2 family (mitochondrial)" ID="ID_1524722397" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AFMID: 2.19-fold Down; FDR = 7e-05; PValue = 8.32e-06; mean CPM = 3.683; arylformamidase" ID="ID_319760034" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KYNU: 1.76-fold Up; FDR = 0.000177; PValue = 2.37e-05; mean CPM = 157.2; kynureninase (L-kynurenine hydrolase)" ID="ID_1700990331" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AOX1: 1.42-fold Up; FDR = 0.00238; PValue = 0.000452; mean CPM = 201.8; aldehyde oxidase 1" ID="ID_1824375462" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACAT1: 1.35-fold Down; FDR = 0.00247; PValue = 0.000471; mean CPM = 32.72; acetyl-CoA acetyltransferase 1" ID="ID_1467668046" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ALDH1A2: 1.81-fold Down; FDR = 0.00471; PValue = 0.000992; mean CPM = 17.58; aldehyde dehydrogenase 1 family, member A2" ID="ID_642342766" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GCDH: 1.32-fold Down; FDR = 0.00538; PValue = 0.00115; mean CPM = 17.15; glutaryl-CoA dehydrogenase" ID="ID_1132899007" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MDM2: 1.32-fold Up; FDR = 0.00555; PValue = 0.00119; mean CPM = 148.6; Uncharacterized protein" ID="ID_845178496" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYP1B1: 1.38-fold Down; FDR = 0.0201; PValue = 0.00528; mean CPM = 273.1; cytochrome P450, family 1, subfamily B, polypeptide 1" ID="ID_897647961" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DDC: 3.34-fold Down; FDR = 0.023; PValue = 0.00617; mean CPM = 0.9003; dopa decarboxylase (aromatic L-amino acid decarboxylase)" ID="ID_865237644" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYP2J2: 2.77-fold Up; FDR = 0.0309; PValue = 0.00873; mean CPM = 1.048; cytochrome P450, family 2, subfamily J, polypeptide 2" ID="ID_1484718594" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYP2A13: 2.01-fold Up; FDR = 0.0381; PValue = 0.0112; mean CPM = 1.749; cytochrome P450, family 2, subfamily A, polypeptide 13" ID="ID_1732354097" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYP19A1: 2-fold Down; FDR = 0.0384; PValue = 0.0113; mean CPM = 1.909; cytochrome P450, family 19, subfamily A, polypeptide 1" ID="ID_105054693" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAOB: 1.82-fold Down; FDR = 0.116; PValue = 0.0418; mean CPM = 1.532; monoamine oxidase B" ID="ID_558947657" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="UBE3A: 1.2-fold Down; FDR = 0.117; PValue = 0.0423; mean CPM = 14.75; Ubiquitin-protein ligase E3A isoform 3; Uncharacterized protein" ID="ID_708742153" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACMSD: 2.19-fold Down; FDR = 0.14; PValue = 0.0529; mean CPM = 0.9416; aminocarboxymuconate semialdehyde decarboxylase" ID="ID_123776655" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYP2F1: 1.24-fold Down; FDR = 0.229; PValue = 0.0971; mean CPM = 5.289; cytochrome P450, family 2, subfamily F, polypeptide 1" ID="ID_801180336" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="UBE3A: 1.12-fold Down; FDR = 0.245; PValue = 0.105; mean CPM = 67.15; ubiquitin protein ligase E3A" ID="ID_937026712" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRMT1: 1.11-fold Down; FDR = 0.34; PValue = 0.158; mean CPM = 156.5; protein arginine methyltransferase 1" ID="ID_389483546" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="UBR5: 1.1-fold Down; FDR = 0.4; PValue = 0.194; mean CPM = 515.4; ubiquitin protein ligase E3 component n-recognin 5" ID="ID_672788732" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HADH: 1.1-fold Up; FDR = 0.419; PValue = 0.205; mean CPM = 32.14; hydroxyacyl-CoA dehydrogenase" ID="ID_1224845265" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ALDH1A1: 1.23-fold Down; FDR = 0.628; PValue = 0.351; mean CPM = 4.599; aldehyde dehydrogenase 1 family, member A1" ID="ID_44577078" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYP1A1: 1.35-fold Up; FDR = 0.658; PValue = 0.373; mean CPM = 1.117; cytochrome P450, family 1, subfamily A, polypeptide 1" ID="ID_659677606" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYP4F12: 1.46-fold Down; FDR = 0.698; PValue = 0.406; mean CPM = 1.446; cytochrome P450, family 4, subfamily F, polypeptide 12" ID="ID_1500801633" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSD17B10: 1.06-fold Down; FDR = 0.735; PValue = 0.437; mean CPM = 95.79; hydroxysteroid (17-beta) dehydrogenase 10" ID="ID_775956661" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RNF25: 1.06-fold Down; FDR = 0.747; PValue = 0.447; mean CPM = 22.86; ring finger protein 25" ID="ID_531814288" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYP2C18: 1.22-fold Up; FDR = 0.909; PValue = 0.687; mean CPM = 0.8257; Cytochrome P450 2C18; Uncharacterized protein" ID="ID_1087613675" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ASMT: 1.14-fold Up; FDR = 0.911; PValue = 0.701; mean CPM = 0.7932; Macaca mulatta hydroxyindole O-methyltransferase (HIOMT), mRNA." ID="ID_411274284" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AANAT: 1.07-fold Up; FDR = 1; PValue = 0.869; mean CPM = 0.9312; aralkylamine N-acetyltransferase" ID="ID_1631020114" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HAAO: 1.06-fold Up; FDR = 1; PValue = 0.87; mean CPM = 0.9953; 3-hydroxyanthranilate 3,4-dioxygenase" ID="ID_1722560441" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ECHS1: 1.01-fold Up; FDR = 1; PValue = 0.885; mean CPM = 49.79; enoyl CoA hydratase, short chain, 1, mitochondrial" ID="ID_1261467367" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYP1A2: 1.1-fold Up; FDR = 1; PValue = 0.958; mean CPM = 0.8552; cytochrome P450, family 1, subfamily A, polypeptide 2" ID="ID_716636166" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INMT: 1.05-fold Down; FDR = 1; PValue = 0.989; mean CPM = 0.7994; indolethylamine N-methyltransferase" ID="ID_1904959374" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYP2E1: No Change; FDR = 1; PValue = 0.995; mean CPM = 0.8039; cytochrome P450, family 2, subfamily E, polypeptide 1" ID="ID_188413521" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-9 signaling pathway (WP22:Rev45370): FDR = 1.6e-09, PValue = 1.25e-10" ID="ID_1476946550" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1913684398" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_82483332" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_661980264" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_378519533" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_60973076" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK3: 2.31-fold Up; FDR = 0.00186; PValue = 0.000342; mean CPM = 2.154; Janus kinase 3" ID="ID_587342868" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1633578572" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_1458857740" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_707306129" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_499947453" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL9R: 2.21-fold Down; FDR = 0.63; PValue = 0.352; mean CPM = 0.8661; interleukin 9 receptor" ID="ID_504526366" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1752203608" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL9: 1.14-fold Up; FDR = 0.911; PValue = 0.705; mean CPM = 0.7910; interleukin 9" ID="ID_540512099" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK9: 1.02-fold Down; FDR = 0.942; PValue = 0.76; mean CPM = 37.82; cyclin-dependent kinase 9" ID="ID_1161764157" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="TGF Beta Signaling Pathway (WP560:Rev45086): FDR = 2.62e-09, PValue = 2.18e-10" ID="ID_1541231830" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1370229559" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGIF1: 2.91-fold Up; FDR = 3.93e-17; PValue = 2.79e-19; mean CPM = 62.45; Uncharacterized protein" ID="ID_572860867" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_629174375" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZFYVE9: 1.55-fold Up; FDR = 2.39e-08; PValue = 1.15e-09; mean CPM = 52.92; zinc finger, FYVE domain containing 9" ID="ID_206488924" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INHBA: 2.52-fold Down; FDR = 1.51e-07; PValue = 8.85e-09; mean CPM = 229.2; inhibin, beta A" ID="ID_922468905" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THBS1: 2.74-fold Down; FDR = 1.68e-06; PValue = 1.28e-07; mean CPM = 25785; thrombospondin 1" ID="ID_295730107" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZEB2: 1.38-fold Up; FDR = 6.66e-05; PValue = 7.87e-06; mean CPM = 234.5; zinc finger E-box binding homeobox 2" ID="ID_1363638451" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPP1: 2.25-fold Down; FDR = 7.74e-05; PValue = 9.29e-06; mean CPM = 35.33; secreted phosphoprotein 1" ID="ID_1475893944" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFBR3: 1.65-fold Up; FDR = 8.06e-05; PValue = 9.72e-06; mean CPM = 15.22; Uncharacterized protein" ID="ID_1260839174" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD3: 1.38-fold Up; FDR = 0.000573; PValue = 8.94e-05; mean CPM = 114.9; SMAD family member 3" ID="ID_814533875" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT1: 7.1-fold Down; FDR = 0.000659; PValue = 0.000105; mean CPM = 2.664; wingless-type MMTV integration site family, member 1" ID="ID_1920397993" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAMBI: 1.87-fold Down; FDR = 0.0018; PValue = 0.000329; mean CPM = 4.991; BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)" ID="ID_484581241" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SERPINE1: 1.58-fold Down; FDR = 0.00232; PValue = 0.000438; mean CPM = 5294; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1" ID="ID_622985972" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD7: 1.33-fold Down; FDR = 0.00568; PValue = 0.00123; mean CPM = 67.59; SMAD family member 7" ID="ID_538607063" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD9: 1.6-fold Down; FDR = 0.00749; PValue = 0.00168; mean CPM = 9.655; SMAD family member 9" ID="ID_585149649" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_1143157710" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD2: 1.2-fold Up; FDR = 0.034; PValue = 0.00976; mean CPM = 57.10; SMAD family member 2" ID="ID_1786024083" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFBR1: 1.2-fold Up; FDR = 0.037; PValue = 0.0108; mean CPM = 90.92; transforming growth factor, beta receptor 1" ID="ID_1942706864" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1321008977" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTNNB1: 1.2-fold Up; FDR = 0.0498; PValue = 0.0153; mean CPM = 558.3; catenin (cadherin-associated protein), beta 1, 88kDa" ID="ID_1486595751" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFBR2: 1.19-fold Up; FDR = 0.0643; PValue = 0.0208; mean CPM = 350.8; transforming growth factor, beta receptor II (70/80kDa)" ID="ID_1971233988" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_1893903091" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOG: 1.94-fold Down; FDR = 0.0887; PValue = 0.0304; mean CPM = 5.830; noggin" ID="ID_28114525" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_743522924" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TFE3: 1.16-fold Down; FDR = 0.107; PValue = 0.0379; mean CPM = 71.56; Transcription factor E3; Uncharacterized protein" ID="ID_1659215064" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BMP4: 1.86-fold Down; FDR = 0.119; PValue = 0.0432; mean CPM = 2.163; bone morphogenetic protein 4" ID="ID_744695355" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_1622202283" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1574082259" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENG: 1.16-fold Up; FDR = 0.154; PValue = 0.0595; mean CPM = 292.6; endoglin" ID="ID_1919219718" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FST: 1.23-fold Down; FDR = 0.237; PValue = 0.101; mean CPM = 51.16; follistatin" ID="ID_601381221" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EP300: 1.11-fold Up; FDR = 0.312; PValue = 0.142; mean CPM = 162.8; E1A binding protein p300" ID="ID_1751967701" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RUNX2: 1.24-fold Down; FDR = 0.328; PValue = 0.152; mean CPM = 8.937; runt-related transcription factor 2" ID="ID_1217190733" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RUNX3: 1.41-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 1.666; runt-related transcription factor 3" ID="ID_1108701966" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_595319928" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD5: 1.08-fold Up; FDR = 0.588; PValue = 0.321; mean CPM = 38.78; SMAD family member 5" ID="ID_968388107" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LEF1: 1.2-fold Up; FDR = 0.691; PValue = 0.4; mean CPM = 2.488; lymphoid enhancer-binding factor 1" ID="ID_1370715217" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LIF: 1.07-fold Down; FDR = 0.702; PValue = 0.409; mean CPM = 148.6; leukemia inhibitory factor (cholinergic differentiation factor)" ID="ID_822912105" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB6: 1.4-fold Down; FDR = 0.732; PValue = 0.434; mean CPM = 0.9377; Integrin beta" ID="ID_501501751" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD1: 1.07-fold Up; FDR = 0.768; PValue = 0.466; mean CPM = 16.45; SMAD family member 1" ID="ID_1284616240" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000015002: 1.4-fold Up; FDR = 0.849; PValue = 0.559; mean CPM = 0.8013; Uncharacterized protein" ID="ID_272063509" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000015002: 1.4-fold Up; FDR = 0.849; PValue = 0.559; mean CPM = 0.8013; Uncharacterized protein" ID="ID_1009828368" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FKBP1A: 1.04-fold Down; FDR = 0.851; PValue = 0.562; mean CPM = 209.1; Peptidyl-prolyl cis-trans isomerase" ID="ID_1340089456" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOXH1: 1.24-fold Down; FDR = 0.879; PValue = 0.598; mean CPM = 0.9508; forkhead box H1" ID="ID_1127170485" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LEFTY1: 1.66-fold Up; FDR = 0.887; PValue = 0.609; mean CPM = 0.8601; left-right determination factor 1" ID="ID_86596805" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_970164267" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_1422247869" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD4: 1.03-fold Down; FDR = 0.906; PValue = 0.666; mean CPM = 43.02; SMAD family member 4" ID="ID_340498084" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZNF423: 1.17-fold Down; FDR = 0.916; PValue = 0.715; mean CPM = 1.462; zinc finger protein 423" ID="ID_1171485791" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB1: 1.02-fold Down; FDR = 0.936; PValue = 0.749; mean CPM = 62.61; transforming growth factor, beta 1" ID="ID_791648481" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SKIL: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 66.09; SKI-like oncogene" ID="ID_579081719" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREBBP: 1.01-fold Down; FDR = 0.993; PValue = 0.847; mean CPM = 137.7; CREB binding protein" ID="ID_403670201" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGF: 1.06-fold Down; FDR = 1; PValue = 0.885; mean CPM = 0.8917; epidermal growth factor" ID="ID_854481966" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Focal Adhesion (WP306:Rev45270): FDR = 3.46e-09, PValue = 3.18e-10" ID="ID_442681166" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="COL4A1: 7.03-fold Down; FDR = 1.47e-15; PValue = 1.34e-17; mean CPM = 3419; collagen, type IV, alpha 1" ID="ID_1537323577" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL5A1: 4.69-fold Down; FDR = 3.09e-15; PValue = 2.99e-17; mean CPM = 1718; collagen, type V, alpha 1" ID="ID_1768453290" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL3A1: 20.5-fold Down; FDR = 5.71e-15; PValue = 5.82e-17; mean CPM = 5961; collagen, type III, alpha 1" ID="ID_494198675" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL11A1: 12.2-fold Down; FDR = 8.67e-15; PValue = 9.24e-17; mean CPM = 318.0; collagen, type XI, alpha 1" ID="ID_1165517196" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA5: 3.79-fold Down; FDR = 1.33e-14; PValue = 1.48e-16; mean CPM = 1237; integrin, alpha 5 (fibronectin receptor, alpha polypeptide)" ID="ID_1747828806" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFRA: 2.76-fold Up; FDR = 3.93e-14; PValue = 4.67e-16; mean CPM = 492.9; platelet-derived growth factor receptor, alpha polypeptide" ID="ID_522296839" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL1A1: 21.5-fold Down; FDR = 1.13e-13; PValue = 1.5e-15; mean CPM = 15389; collagen, type I, alpha 1" ID="ID_1885484852" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VEGFC: 2-fold Up; FDR = 1.3e-13; PValue = 1.76e-15; mean CPM = 238.4; Macaca mulatta vascular endothelial growth factor C (VEGFC), mRNA." ID="ID_1499464765" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHOB: 2.87-fold Down; FDR = 2.74e-13; PValue = 3.96e-15; mean CPM = 84.32; ras homolog gene family, member B" ID="ID_368342440" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MET: 2.57-fold Up; FDR = 3.56e-13; PValue = 5.22e-15; mean CPM = 242.4; Macaca mulatta met proto-oncogene (hepatocyte growth factor receptor) (MET), mRNA." ID="ID_630564746" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL1A2: 10.7-fold Down; FDR = 3.82e-13; PValue = 5.68e-15; mean CPM = 17923; collagen, type I, alpha 2" ID="ID_685833110" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VCL: 2.48-fold Down; FDR = 5.94e-13; PValue = 9.16e-15; mean CPM = 1013; vinculin" ID="ID_1763457333" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMC1: 2.28-fold Down; FDR = 6.46e-13; PValue = 1.01e-14; mean CPM = 812.1; laminin, gamma 1 (formerly LAMB2)" ID="ID_811652547" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016591: 4.2-fold Down; FDR = 1.3e-11; PValue = 2.78e-13; mean CPM = 34.90; Uncharacterized protein" ID="ID_1228502266" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016587: 4.92-fold Down; FDR = 1.6e-11; PValue = 3.5e-13; mean CPM = 51.70; Uncharacterized protein" ID="ID_279238596" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAV: 2.64-fold Down; FDR = 6.04e-11; PValue = 1.51e-12; mean CPM = 337.3; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)" ID="ID_1075457377" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND3: 2.27-fold Down; FDR = 8.38e-11; PValue = 2.15e-12; mean CPM = 86.90; cyclin D3" ID="ID_388121535" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC2: 1.96-fold Up; FDR = 1.01e-10; PValue = 2.62e-12; mean CPM = 53.58; baculoviral IAP repeat-containing 2" ID="ID_1667100583" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL5A3: 5.21-fold Down; FDR = 1.78e-10; PValue = 4.98e-12; mean CPM = 79.70; collagen, type V, alpha 3" ID="ID_1905683895" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THBS2: 6.46-fold Down; FDR = 3.61e-10; PValue = 1.1e-11; mean CPM = 199.9; thrombospondin 2" ID="ID_1888357779" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB8: 3.97-fold Up; FDR = 6.37e-10; PValue = 2.06e-11; mean CPM = 11.37; integrin, beta 8" ID="ID_988822914" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA2: 2.84-fold Up; FDR = 7.38e-10; PValue = 2.42e-11; mean CPM = 176.3; integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)" ID="ID_1444230344" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB3: 5.02-fold Down; FDR = 1.72e-09; PValue = 6.17e-11; mean CPM = 43.21; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)" ID="ID_218882046" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL5A2: 2.25-fold Down; FDR = 2.26e-09; PValue = 8.27e-11; mean CPM = 2999; collagen, type V, alpha 2" ID="ID_928687244" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_1206003963" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGFR: 1.84-fold Up; FDR = 6.71e-09; PValue = 2.77e-10; mean CPM = 68.58; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)" ID="ID_50551739" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB5: 1.61-fold Down; FDR = 8.23e-09; PValue = 3.47e-10; mean CPM = 471.0; integrin, beta 5" ID="ID_1003783205" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA10: 4.95-fold Down; FDR = 1.77e-08; PValue = 8.13e-10; mean CPM = 5.184; integrin, alpha 10" ID="ID_80710173" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FLNA: 2.35-fold Down; FDR = 2.01e-08; PValue = 9.45e-10; mean CPM = 7159; filamin A, alpha" ID="ID_1675236838" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TESK2: 4.45-fold Up; FDR = 3.77e-08; PValue = 1.9e-09; mean CPM = 7.759; testis-specific kinase 2" ID="ID_1277263400" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA8: 4.04-fold Down; FDR = 5.89e-08; PValue = 3.12e-09; mean CPM = 145.8; integrin, alpha 8" ID="ID_51964650" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ILK: 1.53-fold Down; FDR = 5.97e-08; PValue = 3.17e-09; mean CPM = 256.9; integrin-linked kinase" ID="ID_592746952" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THBS3: 1.97-fold Up; FDR = 7.19e-08; PValue = 3.88e-09; mean CPM = 128.6; thrombospondin 3" ID="ID_1779668503" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COMP: 4.64-fold Down; FDR = 7.47e-08; PValue = 4.04e-09; mean CPM = 13.27; cartilage oligomeric matrix protein" ID="ID_312316791" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1B: 1.55-fold Up; FDR = 2.39e-07; PValue = 1.46e-08; mean CPM = 135.3; Ras-related protein Rap-1b; Ras-related protein Rap-1b isoform 1; Uncharacterized protein" ID="ID_1798886136" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFA: 1.92-fold Down; FDR = 2.56e-07; PValue = 1.58e-08; mean CPM = 22.99; platelet-derived growth factor alpha polypeptide" ID="ID_1252398212" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNC: 1.97-fold Down; FDR = 4.07e-07; PValue = 2.63e-08; mean CPM = 2667; tenascin C" ID="ID_92485029" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1637190167" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYLK: 2.29-fold Down; FDR = 1.02e-06; PValue = 7.45e-08; mean CPM = 128.3; myosin light chain kinase" ID="ID_1181051234" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1163920450" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_1906207596" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THBS1: 2.74-fold Down; FDR = 1.68e-06; PValue = 1.28e-07; mean CPM = 25785; thrombospondin 1" ID="ID_589811788" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC3: 2.79-fold Up; FDR = 1.74e-06; PValue = 1.32e-07; mean CPM = 95.34; baculoviral IAP repeat-containing 3" ID="ID_775780836" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1012081067" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC3: 1.68-fold Down; FDR = 2.72e-06; PValue = 2.19e-07; mean CPM = 13.98; ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)" ID="ID_1159605673" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1: 5.76-fold Down; FDR = 6.73e-06; PValue = 6.04e-07; mean CPM = 1.536; insulin-like growth factor 1 (somatomedin C)" ID="ID_56452074" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K3: 1.45-fold Down; FDR = 7.01e-06; PValue = 6.34e-07; mean CPM = 180.1; mitogen-activated protein kinase kinase 3" ID="ID_1498832698" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMC2: 2.28-fold Down; FDR = 9.83e-06; PValue = 9.24e-07; mean CPM = 16.99; laminin, gamma 2" ID="ID_732998738" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1R: 1.51-fold Down; FDR = 1.02e-05; PValue = 9.61e-07; mean CPM = 213.2; insulin-like growth factor 1 receptor" ID="ID_157000734" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_275206293" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYL6: 1.52-fold Down; FDR = 1.71e-05; PValue = 1.71e-06; mean CPM = 587.5; myosin, light chain 6, alkali, smooth muscle and non-muscle" ID="ID_260712601" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNK2: 1.75-fold Down; FDR = 3.26e-05; PValue = 3.5e-06; mean CPM = 44.07; tyrosine kinase, non-receptor, 2" ID="ID_363963745" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K5: 1.55-fold Up; FDR = 7.6e-05; PValue = 9.12e-06; mean CPM = 16.82; mitogen-activated protein kinase kinase 5" ID="ID_50051077" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPP1: 2.25-fold Down; FDR = 7.74e-05; PValue = 9.29e-06; mean CPM = 35.33; secreted phosphoprotein 1" ID="ID_1547361484" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARHGAP5: 1.36-fold Up; FDR = 0.000133; PValue = 1.7e-05; mean CPM = 130.2; Rho GTPase activating protein 5" ID="ID_425461137" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCAR1: 1.36-fold Up; FDR = 0.000193; PValue = 2.61e-05; mean CPM = 210.4; breast cancer anti-estrogen resistance 1" ID="ID_1066315343" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C17orf57: 5.51-fold Down; FDR = 0.000238; PValue = 3.33e-05; mean CPM = 1.571; EF-hand domain-containing protein C17orf57" ID="ID_1572848270" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL6A2: 1.47-fold Down; FDR = 0.000287; PValue = 4.1e-05; mean CPM = 1544; collagen, type VI, alpha 2" ID="ID_1857103205" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HGF: 1.85-fold Down; FDR = 0.000377; PValue = 5.58e-05; mean CPM = 137.4; hepatocyte growth factor (hepapoietin A; scatter factor)" ID="ID_643442432" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB2: 1.48-fold Down; FDR = 0.000398; PValue = 5.93e-05; mean CPM = 695.6; laminin, beta 2 (laminin S)" ID="ID_1880438017" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA3: 1.34-fold Down; FDR = 0.000518; PValue = 7.96e-05; mean CPM = 126.8; integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)" ID="ID_1519171129" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAD: 1.36-fold Down; FDR = 0.000605; PValue = 9.52e-05; mean CPM = 48.46; BCL2-associated agonist of cell death" ID="ID_522555625" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZYX: 1.29-fold Down; FDR = 0.00237; PValue = 0.00045; mean CPM = 287.5; Uncharacterized protein" ID="ID_995695664" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK3: 3.55-fold Up; FDR = 0.00273; PValue = 0.000527; mean CPM = 1.136; p21 protein (Cdc42/Rac)-activated kinase 3" ID="ID_513478880" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHOA: 1.28-fold Down; FDR = 0.00295; PValue = 0.000575; mean CPM = 277.8; ras homolog gene family, member A" ID="ID_523998117" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TXK: 3.95-fold Up; FDR = 0.00318; PValue = 0.000629; mean CPM = 1.067; TXK tyrosine kinase" ID="ID_704774531" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1B: 1.43-fold Up; FDR = 0.00346; PValue = 0.000693; mean CPM = 12.81; RAP1B, member of RAS oncogene family" ID="ID_624755622" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB4: 1.66-fold Down; FDR = 0.00369; PValue = 0.000748; mean CPM = 5.291; integrin, beta 4" ID="ID_669361422" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIP5K1C: 1.27-fold Down; FDR = 0.00491; PValue = 0.00104; mean CPM = 37.75; phosphatidylinositol-4-phosphate 5-kinase, type I, gamma" ID="ID_1642620472" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAV1: 1.33-fold Down; FDR = 0.00575; PValue = 0.00125; mean CPM = 228.7; caveolin-1" ID="ID_1061871276" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VASP: 1.26-fold Down; FDR = 0.00581; PValue = 0.00126; mean CPM = 250.9; vasodilator-stimulated phosphoprotein" ID="ID_260243954" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLN1: 1.26-fold Down; FDR = 0.0101; PValue = 0.00238; mean CPM = 1820; talin 1" ID="ID_680768649" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFB: 1.97-fold Down; FDR = 0.0133; PValue = 0.00326; mean CPM = 2.424; platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)" ID="ID_700437439" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FYN: 1.22-fold Up; FDR = 0.0156; PValue = 0.00393; mean CPM = 92.94; FYN oncogene related to SRC, FGR, YES" ID="ID_236269271" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FARP2: 1.24-fold Down; FDR = 0.0162; PValue = 0.00411; mean CPM = 30.03; FERM, RhoGEF and pleckstrin domain protein 2" ID="ID_1250935744" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FN1: 1.7-fold Down; FDR = 0.0164; PValue = 0.00417; mean CPM = 40317; fibronectin 1" ID="ID_360463558" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB2: 1.55-fold Down; FDR = 0.0187; PValue = 0.00485; mean CPM = 34.87; Integrin beta" ID="ID_899026437" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA2B: 1.71-fold Down; FDR = 0.0187; PValue = 0.00486; mean CPM = 2.655; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)" ID="ID_1447505830" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_439116814" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1593745439" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC2: 2.96-fold Up; FDR = 0.0309; PValue = 0.00872; mean CPM = 0.9737; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)" ID="ID_1782699828" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KDR: 2.01-fold Up; FDR = 0.0328; PValue = 0.00936; mean CPM = 2.053; kinase insert domain receptor (a type III receptor tyrosine kinase)" ID="ID_168136189" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDPK1: 1.24-fold Down; FDR = 0.0361; PValue = 0.0105; mean CPM = 17.53; 3-phosphoinositide dependent protein kinase-1" ID="ID_707422388" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL2A1: 2.38-fold Down; FDR = 0.0368; PValue = 0.0107; mean CPM = 1.117; Uncharacterized protein" ID="ID_244470952" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK6: 3.06-fold Down; FDR = 0.04; PValue = 0.0118; mean CPM = 0.9224; p21 protein (Cdc42/Rac)-activated kinase 6" ID="ID_643749225" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK4: 1.21-fold Down; FDR = 0.0756; PValue = 0.0252; mean CPM = 16.78; p21 protein (Cdc42/Rac)-activated kinase 4" ID="ID_22675354" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB1: 1.23-fold Up; FDR = 0.0759; PValue = 0.0253; mean CPM = 2700; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)" ID="ID_824843995" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMA4: 1.2-fold Down; FDR = 0.0793; PValue = 0.0266; mean CPM = 624.4; laminin, alpha 4" ID="ID_1509293279" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1A: 1.17-fold Up; FDR = 0.0888; PValue = 0.0304; mean CPM = 37.16; RAP1A, member of RAS oncogene family" ID="ID_557722670" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND1: 1.17-fold Up; FDR = 0.121; PValue = 0.0443; mean CPM = 867.3; cyclin D1" ID="ID_1472194770" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_1659555141" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IBSP: 2.51-fold Down; FDR = 0.128; PValue = 0.0476; mean CPM = 0.8896; integrin-binding sialoprotein" ID="ID_1131754125" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK2: 1.15-fold Up; FDR = 0.134; PValue = 0.0502; mean CPM = 89.49; p21 protein (Cdc42/Rac)-activated kinase 2" ID="ID_1107920363" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_679143201" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1907977390" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTEN: 1.14-fold Up; FDR = 0.166; PValue = 0.065; mean CPM = 89.60; phosphatase and tensin homolog" ID="ID_1157250764" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ROCK2: 1.14-fold Up; FDR = 0.166; PValue = 0.065; mean CPM = 247.7; Rho-associated, coiled-coil containing protein kinase 2" ID="ID_1948784364" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP1R12A: 1.14-fold Up; FDR = 0.167; PValue = 0.0655; mean CPM = 282.7; protein phosphatase 1, regulatory (inhibitor) subunit 12A" ID="ID_178831725" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VWF: 1.42-fold Down; FDR = 0.174; PValue = 0.069; mean CPM = 24.05; von Willebrand factor" ID="ID_816386368" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STYK1: 2-fold Up; FDR = 0.19; PValue = 0.0767; mean CPM = 1.085; serine/threonine/tyrosine kinase 1" ID="ID_1200192625" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1567650316" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PARVB: 1.14-fold Down; FDR = 0.199; PValue = 0.0817; mean CPM = 34.65; parvin, beta" ID="ID_1403540357" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_992454266" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BRAF: 1.14-fold Down; FDR = 0.228; PValue = 0.0964; mean CPM = 24.98; v-raf murine sarcoma viral oncogene homolog B1" ID="ID_583686981" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ERBB2: 1.14-fold Down; FDR = 0.23; PValue = 0.0977; mean CPM = 119.0; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)" ID="ID_1050888004" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAV2: 1.14-fold Down; FDR = 0.24; PValue = 0.103; mean CPM = 25.69; caveolin 2" ID="ID_1675235079" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_500784035" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014969: 1.93-fold Down; FDR = 0.303; PValue = 0.137; mean CPM = 0.9384; Uncharacterized protein" ID="ID_1506212054" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB3: 1.6-fold Down; FDR = 0.303; PValue = 0.137; mean CPM = 1.445; laminin, beta 3" ID="ID_884510379" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_1085091975" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND2: 1.2-fold Up; FDR = 0.335; PValue = 0.155; mean CPM = 76.91; cyclin D2" ID="ID_1065748759" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CB: 1.13-fold Down; FDR = 0.383; PValue = 0.183; mean CPM = 21.07; phosphoinositide-3-kinase, catalytic, beta polypeptide" ID="ID_120761615" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2: 1.48-fold Up; FDR = 0.384; PValue = 0.184; mean CPM = 1.344; Uncharacterized protein" ID="ID_1031785389" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2: 1.1-fold Up; FDR = 0.394; PValue = 0.191; mean CPM = 102.5; PTK2 protein tyrosine kinase 2" ID="ID_1878060502" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK6: 1.34-fold Up; FDR = 0.407; PValue = 0.198; mean CPM = 2.043; mitogen-activated protein kinase 6" ID="ID_230264388" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK12: 1.19-fold Down; FDR = 0.422; PValue = 0.208; mean CPM = 6.569; mitogen-activated protein kinase 12" ID="ID_1884855532" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNN: 1.32-fold Up; FDR = 0.425; PValue = 0.209; mean CPM = 2.061; tenascin N" ID="ID_1600020818" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THBS4: 1.64-fold Down; FDR = 0.498; PValue = 0.257; mean CPM = 0.9543; thrombospondin 4" ID="ID_1029901255" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VEGFB: 1.1-fold Down; FDR = 0.512; PValue = 0.267; mean CPM = 16.03; vascular endothelial growth factor B" ID="ID_689157676" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGR: 1.63-fold Up; FDR = 0.516; PValue = 0.269; mean CPM = 1.191; Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog" ID="ID_1922063938" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R5: 1.45-fold Up; FDR = 0.53; PValue = 0.279; mean CPM = 1.188; phosphoinositide-3-kinase, regulatory subunit 5" ID="ID_1046881024" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYLK2: 1.56-fold Down; FDR = 0.541; PValue = 0.288; mean CPM = 0.9259; myosin light chain kinase 2" ID="ID_1860464519" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC3: 1.37-fold Down; FDR = 0.584; PValue = 0.318; mean CPM = 1.193; SHC-transforming protein 3; Uncharacterized protein" ID="ID_893551837" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA9: 1.3-fold Down; FDR = 0.595; PValue = 0.326; mean CPM = 1.685; integrin, alpha 9" ID="ID_201019425" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDC42: 1.07-fold Down; FDR = 0.608; PValue = 0.335; mean CPM = 91.67; cell division cycle 42" ID="ID_656415043" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL4A6: 1.4-fold Down; FDR = 0.631; PValue = 0.353; mean CPM = 1.078; collagen, type IV, alpha 6" ID="ID_1227714526" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VTN: 1.19-fold Up; FDR = 0.669; PValue = 0.382; mean CPM = 2.950; vitronectin" ID="ID_749080005" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014966: 1.43-fold Down; FDR = 0.72; PValue = 0.423; mean CPM = 0.9009; Uncharacterized protein" ID="ID_764777244" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA4: 1.16-fold Down; FDR = 0.722; PValue = 0.425; mean CPM = 5.425; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)" ID="ID_715479863" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAM: 1.44-fold Down; FDR = 0.73; PValue = 0.432; mean CPM = 0.9052; integrin, alpha M (complement component 3 receptor 3 subunit)" ID="ID_878036977" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB6: 1.4-fold Down; FDR = 0.732; PValue = 0.434; mean CPM = 0.9377; Integrin beta" ID="ID_1099541567" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAPGEF1: 1.05-fold Down; FDR = 0.763; PValue = 0.462; mean CPM = 70.38; Rap guanine nucleotide exchange factor (GEF) 1" ID="ID_1205934463" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRK: 1.05-fold Up; FDR = 0.791; PValue = 0.488; mean CPM = 59.92; v-crk sarcoma virus CT10 oncogene homolog (avian)" ID="ID_998219437" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HCK: 1.3-fold Down; FDR = 0.797; PValue = 0.494; mean CPM = 0.9272; Uncharacterized protein" ID="ID_1985324832" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DOCK1: 1.05-fold Up; FDR = 0.825; PValue = 0.524; mean CPM = 165.2; dedicator of cytokinesis 1" ID="ID_1400428433" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FLT1: 1.08-fold Down; FDR = 0.849; PValue = 0.558; mean CPM = 28.21; fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)" ID="ID_967168280" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAD: 1.66-fold Down; FDR = 0.85; PValue = 0.56; mean CPM = 0.8625; integrin, alpha D" ID="ID_903302083" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV1: 1.25-fold Down; FDR = 0.858; PValue = 0.572; mean CPM = 0.9515; vav 1 guanine nucleotide exchange factor" ID="ID_842556825" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_950612246" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK7: 1.04-fold Down; FDR = 0.899; PValue = 0.632; mean CPM = 16.93; Uncharacterized protein" ID="ID_1435199257" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK1: 1.03-fold Down; FDR = 0.911; PValue = 0.705; mean CPM = 18.65; p21 protein (Cdc42/Rac)-activated kinase 1" ID="ID_311734279" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_1853819660" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_165160981" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL11A2: 1.03-fold Down; FDR = 1; PValue = 0.872; mean CPM = 2.131; collagen, type XI, alpha 2" ID="ID_186411975" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFRB: 1.01-fold Up; FDR = 1; PValue = 0.883; mean CPM = 391.1; platelet-derived growth factor receptor, beta polypeptide" ID="ID_1951825000" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGF: 1.06-fold Down; FDR = 1; PValue = 0.885; mean CPM = 0.8917; epidermal growth factor" ID="ID_286740988" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNXB: 1.03-fold Up; FDR = 1; PValue = 0.909; mean CPM = 1.078; tenascin XB" ID="ID_1201053224" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R4: 1.01-fold Down; FDR = 1; PValue = 0.913; mean CPM = 41.33; phosphoinositide-3-kinase, regulatory subunit 4" ID="ID_453235103" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK7: 1.01-fold Up; FDR = 1; PValue = 0.923; mean CPM = 0.8495; p21 protein (Cdc42/Rac)-activated kinase 7" ID="ID_1645885949" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK4: 1.19-fold Down; FDR = 1; PValue = 0.95; mean CPM = 0.8611; mitogen-activated protein kinase 4" ID="ID_1564893890" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAL: 1.03-fold Up; FDR = 1; PValue = 0.95; mean CPM = 1.035; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)" ID="ID_1302048564" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB7: 1.01-fold Down; FDR = 1; PValue = 0.968; mean CPM = 2.025; integrin, beta 7" ID="ID_174953856" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SRMS: 1.01-fold Down; FDR = 1; PValue = 0.978; mean CPM = 0.8505; src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites" ID="ID_1469959770" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAV3: 1.02-fold Down; FDR = 1; PValue = 0.98; mean CPM = 0.7970; caveolin 3" ID="ID_1403647800" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNR: 1.08-fold Down; FDR = 1; PValue = 0.984; mean CPM = 0.8556; tenascin R (restrictin, janusin)" ID="ID_1249975621" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FIGF: 1.07-fold Up; FDR = 1; PValue = 0.995; mean CPM = 0.8037; c-fos induced growth factor (vascular endothelial growth factor D)" ID="ID_1325744626" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK6: 1.04-fold Up; FDR = 1; PValue = 1; mean CPM = 0.8141; PTK6 protein tyrosine kinase 6" ID="ID_121835933" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="p38 MAPK Signaling Pathway (WP400:Rev45281): FDR = 3.46e-09, PValue = 3.24e-10" ID="ID_1726280579" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_851733270" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_1106743175" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MEF2D: 1.73-fold Down; FDR = 2.02e-08; PValue = 9.5e-10; mean CPM = 61.43; myocyte enhancer factor 2D" ID="ID_1837006329" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DDIT3: 2.05-fold Up; FDR = 1.46e-06; PValue = 1.09e-07; mean CPM = 45.52; DNA-damage-inducible transcript 3" ID="ID_603473581" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA5: 3.28-fold Up; FDR = 1.4e-05; PValue = 1.36e-06; mean CPM = 2.288; ribosomal protein S6 kinase, 90kDa, polypeptide 5" ID="ID_186800084" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF2: 1.34-fold Up; FDR = 0.000403; PValue = 6.01e-05; mean CPM = 39.83; activating transcription factor 2" ID="ID_328783094" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_1573546926" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAX: 1.28-fold Up; FDR = 0.00569; PValue = 0.00123; mean CPM = 29.78; MYC associated factor X" ID="ID_1937161249" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB1: 1.21-fold Up; FDR = 0.0313; PValue = 0.00884; mean CPM = 36.07; cAMP responsive element binding protein 1" ID="ID_57048588" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRADD: 1.22-fold Up; FDR = 0.0319; PValue = 0.00907; mean CPM = 34.75; TNFRSF1A-associated via death domain" ID="ID_1448586138" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFBR1: 1.2-fold Up; FDR = 0.037; PValue = 0.0108; mean CPM = 90.92; transforming growth factor, beta receptor 1" ID="ID_811897468" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_836863802" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_1459351495" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MKNK1: 1.27-fold Down; FDR = 0.0706; PValue = 0.0232; mean CPM = 9.169; MAP kinase interacting serine/threonine kinase 1" ID="ID_406977128" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K9: 1.62-fold Down; FDR = 0.177; PValue = 0.0705; mean CPM = 1.806; mitogen-activated protein kinase kinase kinase 9" ID="ID_171594939" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_473316378" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_1875852058" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPKAPK5: 1.15-fold Down; FDR = 0.297; PValue = 0.134; mean CPM = 13.06; mitogen-activated protein kinase-activated protein kinase 5" ID="ID_1158596829" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1955440882" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K5: 1.21-fold Down; FDR = 0.6; PValue = 0.33; mean CPM = 8.023; mitogen-activated protein kinase kinase kinase 5" ID="ID_921128597" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDC42: 1.07-fold Down; FDR = 0.608; PValue = 0.335; mean CPM = 91.67; cell division cycle 42" ID="ID_1559814084" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPKAPK2: 1.06-fold Down; FDR = 0.733; PValue = 0.435; mean CPM = 82.16; mitogen-activated protein kinase-activated protein kinase 2" ID="ID_1410457315" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLA2G4A: 1.08-fold Down; FDR = 0.836; PValue = 0.541; mean CPM = 40.53; phospholipase A2, group IVA (cytosolic, calcium-dependent)" ID="ID_110999436" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASGRF1: 1.14-fold Down; FDR = 0.903; PValue = 0.648; mean CPM = 1.594; Ras protein-specific guanine nucleotide-releasing factor 1" ID="ID_633117912" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB2: 1.05-fold Down; FDR = 0.903; PValue = 0.655; mean CPM = 110.8; transforming growth factor, beta 2" ID="ID_1271228299" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_1649730866" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_1531937969" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_886787088" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DAXX: No Change; FDR = 1; PValue = 0.984; mean CPM = 106.5; Death domain-associated protein 6 (Daxx)(hDaxx)(Fas death domain-associated protein)(ETS1-associated protein 1)(EAP1)" ID="ID_661242063" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Osteoblast Signaling (WP322:Rev45323): FDR = 4.04e-09, PValue = 4.16e-10" ID="ID_474324890" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="PDGFRA: 2.76-fold Up; FDR = 3.93e-14; PValue = 4.67e-16; mean CPM = 492.9; platelet-derived growth factor receptor, alpha polypeptide" ID="ID_15941056" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL1A1: 21.5-fold Down; FDR = 1.13e-13; PValue = 1.5e-15; mean CPM = 15389; collagen, type I, alpha 1" ID="ID_1665307844" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAV: 2.64-fold Down; FDR = 6.04e-11; PValue = 1.51e-12; mean CPM = 337.3; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)" ID="ID_515316948" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB3: 5.02-fold Down; FDR = 1.72e-09; PValue = 6.17e-11; mean CPM = 43.21; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)" ID="ID_1419854319" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C17orf57: 5.51-fold Down; FDR = 0.000238; PValue = 3.33e-05; mean CPM = 1.571; EF-hand domain-containing protein C17orf57" ID="ID_1568251131" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFB: 1.97-fold Down; FDR = 0.0133; PValue = 0.00326; mean CPM = 2.424; platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)" ID="ID_1516419790" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF11: 1.8-fold Up; FDR = 0.039; PValue = 0.0115; mean CPM = 2.535; tumor necrosis factor (ligand) superfamily, member 11" ID="ID_413475135" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTH1R: 2-fold Down; FDR = 0.0838; PValue = 0.0284; mean CPM = 1.299; parathyroid hormone 1 receptor" ID="ID_1020258705" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF11B: 1.31-fold Down; FDR = 0.121; PValue = 0.0439; mean CPM = 722.1; Uncharacterized protein" ID="ID_332440898" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IBSP: 2.51-fold Down; FDR = 0.128; PValue = 0.0476; mean CPM = 0.8896; integrin-binding sialoprotein" ID="ID_975260407" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF23: 2.01-fold Down; FDR = 0.188; PValue = 0.0759; mean CPM = 0.9718; fibroblast growth factor 23" ID="ID_930119324" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDGFRB: 1.01-fold Up; FDR = 1; PValue = 0.883; mean CPM = 391.1; platelet-derived growth factor receptor, beta polypeptide" ID="ID_516547990" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTH: No Change; FDR = 1; PValue = 1; mean CPM = 0.7843; parathyroid hormone" ID="ID_470882296" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Apoptosis (WP254:Rev41184): FDR = 4.04e-09, PValue = 4.31e-10" ID="ID_1685411886" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="IRF1: 18.6-fold Up; FDR = 1.53e-21; PValue = 4.24e-24; mean CPM = 240.7; interferon regulatory factor 1" ID="ID_647699996" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF2: 3.25-fold Up; FDR = 2.61e-18; PValue = 1.48e-20; mean CPM = 32.37; interferon regulatory factor 2" ID="ID_944838551" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF7: 14.8-fold Up; FDR = 7.66e-18; PValue = 4.82e-20; mean CPM = 11.54; Macaca mulatta interferon regulatory factor 7 (IRF7), mRNA." ID="ID_236594946" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_1920743516" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF10: 44.5-fold Up; FDR = 2.83e-16; PValue = 2.4e-18; mean CPM = 6.029; Tumor necrosis factor ligand superfamily member 10 isoform 1; Uncharacterized protein" ID="ID_493049620" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PMAIP1: 8.66-fold Up; FDR = 1.12e-12; PValue = 1.84e-14; mean CPM = 31.02; Phorbol-12-myristate-13-acetate-induced protein 1; Uncharacterized protein" ID="ID_1666122990" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP4: 4.99-fold Up; FDR = 6.91e-12; PValue = 1.4e-13; mean CPM = 56.06; Caspase" ID="ID_1533134688" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC2: 1.96-fold Up; FDR = 1.01e-10; PValue = 2.62e-12; mean CPM = 53.58; baculoviral IAP repeat-containing 2" ID="ID_284123524" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CFLAR: 1.87-fold Up; FDR = 5.09e-10; PValue = 1.61e-11; mean CPM = 103.3; CASP8 and FADD-like apoptosis regulator" ID="ID_1082266928" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BID: 1.66-fold Up; FDR = 5.41e-09; PValue = 2.19e-10; mean CPM = 35.19; BH3 interacting domain death agonist" ID="ID_1689275164" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_1470752158" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1973715198" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_517185159" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L1: 1.51-fold Up; FDR = 9.13e-07; PValue = 6.52e-08; mean CPM = 66.15; Bcl-2-like protein 1; Bcl-2-like protein 1 isoform 1; Uncharacterized protein" ID="ID_1677055728" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC3: 2.79-fold Up; FDR = 1.74e-06; PValue = 1.32e-07; mean CPM = 95.34; baculoviral IAP repeat-containing 3" ID="ID_1456589879" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1B: 2.24-fold Up; FDR = 2.68e-06; PValue = 2.16e-07; mean CPM = 19.44; tumor necrosis factor receptor superfamily, member 1B" ID="ID_97366909" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1: 5.76-fold Down; FDR = 6.73e-06; PValue = 6.04e-07; mean CPM = 1.536; insulin-like growth factor 1 (somatomedin C)" ID="ID_1569063294" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1R: 1.51-fold Down; FDR = 1.02e-05; PValue = 9.61e-07; mean CPM = 213.2; insulin-like growth factor 1 receptor" ID="ID_1168386945" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BNIP3L: 1.42-fold Up; FDR = 1.15e-05; PValue = 1.09e-06; mean CPM = 219.7; BCL2/adenovirus E1B 19kDa interacting protein 3-like" ID="ID_878789185" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF1: 2.6-fold Down; FDR = 1.48e-05; PValue = 1.46e-06; mean CPM = 20.19; TNF receptor-associated factor 1" ID="ID_53198035" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_1109491056" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAD: 1.36-fold Down; FDR = 0.000605; PValue = 9.52e-05; mean CPM = 48.46; BCL2-associated agonist of cell death" ID="ID_726543661" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1527933792" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MDM2: 1.32-fold Up; FDR = 0.00555; PValue = 0.00119; mean CPM = 148.6; Uncharacterized protein" ID="ID_819818904" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_1687364274" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP10: 1.81-fold Up; FDR = 0.0175; PValue = 0.0045; mean CPM = 2.876; caspase 10, apoptosis-related cysteine peptidase" ID="ID_1084360255" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1589928113" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIE: 1.3-fold Down; FDR = 0.0272; PValue = 0.00752; mean CPM = 16.93; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon" ID="ID_1233551183" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRADD: 1.22-fold Up; FDR = 0.0319; PValue = 0.00907; mean CPM = 34.75; TNFRSF1A-associated via death domain" ID="ID_203670216" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MCL1: 1.2-fold Up; FDR = 0.0335; PValue = 0.00961; mean CPM = 193.8; myeloid cell leukemia sequence 1 (BCL2-related)" ID="ID_555087439" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_536935483" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP63: 1.81-fold Down; FDR = 0.0567; PValue = 0.0179; mean CPM = 2.228; tumor protein p63" ID="ID_87634995" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP73: 2.3-fold Down; FDR = 0.0601; PValue = 0.0192; mean CPM = 1.058; tumor protein p73" ID="ID_1238980179" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L11: 1.34-fold Up; FDR = 0.0609; PValue = 0.0195; mean CPM = 18.38; BCL2-like 11 (apoptosis facilitator)" ID="ID_486316992" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DFFA: 1.18-fold Down; FDR = 0.0688; PValue = 0.0225; mean CPM = 44.03; DNA fragmentation factor, 45kDa, alpha polypeptide" ID="ID_1823263694" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_1558064405" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DIABLO: 1.17-fold Up; FDR = 0.0849; PValue = 0.0288; mean CPM = 58.69; diablo homolog (Drosophila)" ID="ID_874687385" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FADD: 1.18-fold Down; FDR = 0.0936; PValue = 0.0324; mean CPM = 30.89; Uncharacterized protein" ID="ID_275589121" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_337398879" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF4: 2.95-fold Down; FDR = 0.124; PValue = 0.0456; mean CPM = 0.9773; interferon regulatory factor 4" ID="ID_1484096791" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC5: 1.51-fold Down; FDR = 0.134; PValue = 0.0501; mean CPM = 18.55; Baculoviral IAP repeat-containing protein 5 isoform 1; Uncharacterized protein" ID="ID_1822631632" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1933403372" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XIAP: 1.17-fold Up; FDR = 0.177; PValue = 0.0706; mean CPM = 19.21; X-linked inhibitor of apoptosis" ID="ID_1655618534" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP6: 1.17-fold Up; FDR = 0.197; PValue = 0.0807; mean CPM = 14.25; caspase 6, apoptosis-related cysteine peptidase" ID="ID_879637657" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP7: 1.15-fold Up; FDR = 0.218; PValue = 0.0916; mean CPM = 21.49; caspase 7, apoptosis-related cysteine peptidase" ID="ID_1347721889" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000039103: 1.67-fold Down; FDR = 0.221; PValue = 0.0927; mean CPM = 1.310; Uncharacterized protein" ID="ID_296726195" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1A: 1.11-fold Up; FDR = 0.297; PValue = 0.134; mean CPM = 134.7; tumor necrosis factor receptor superfamily, member 1A" ID="ID_321515092" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HELLS: 1.19-fold Down; FDR = 0.331; PValue = 0.153; mean CPM = 21.44; Uncharacterized protein" ID="ID_880989443" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF10B: 1.13-fold Down; FDR = 0.343; PValue = 0.16; mean CPM = 40.59; tumor necrosis factor receptor superfamily, member 10b" ID="ID_1211899227" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP53: 1.11-fold Down; FDR = 0.364; PValue = 0.172; mean CPM = 33.25; tumor protein p53" ID="ID_1997721485" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF2: 1.42-fold Up; FDR = 0.383; PValue = 0.183; mean CPM = 31.20; insulin-like growth factor 2 (somatomedin A)" ID="ID_1957139514" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2: 1.48-fold Up; FDR = 0.384; PValue = 0.184; mean CPM = 1.344; Uncharacterized protein" ID="ID_1351294071" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BOK: 1.12-fold Down; FDR = 0.416; PValue = 0.204; mean CPM = 14.21; BCL2-related ovarian killer" ID="ID_1669869407" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF6: 2.34-fold Down; FDR = 0.535; PValue = 0.283; mean CPM = 0.8609; interferon regulatory factor 6" ID="ID_163695363" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L2: 1.08-fold Down; FDR = 0.578; PValue = 0.314; mean CPM = 35.23; BCL2-like 2" ID="ID_1808182575" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF3: 1.07-fold Up; FDR = 0.611; PValue = 0.338; mean CPM = 34.56; TNF receptor-associated factor 3" ID="ID_969531079" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_452016075" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF25: 1.2-fold Up; FDR = 0.772; PValue = 0.471; mean CPM = 1.687; tumor necrosis factor receptor superfamily, member 25" ID="ID_732418800" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAX: 1.05-fold Up; FDR = 0.809; PValue = 0.506; mean CPM = 162.4; Uncharacterized protein" ID="ID_572168081" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRADD: 1.1-fold Down; FDR = 0.827; PValue = 0.527; mean CPM = 3.992; CASP2 and RIPK1 domain containing adaptor with death domain" ID="ID_674217787" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GZMB: 1.43-fold Up; FDR = 0.83; PValue = 0.532; mean CPM = 0.7972; granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)" ID="ID_1281334277" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APAF1: 1.05-fold Down; FDR = 0.837; PValue = 0.543; mean CPM = 32.11; apoptotic peptidase activating factor 1" ID="ID_1670013231" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRF1: 1.75-fold Up; FDR = 0.841; PValue = 0.548; mean CPM = 0.8583; perforin 1 (pore forming protein)" ID="ID_896942243" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRF5: 1.06-fold Down; FDR = 0.85; PValue = 0.561; mean CPM = 9.280; interferon regulatory factor 5" ID="ID_1191709264" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYCS: 1.05-fold Up; FDR = 0.854; PValue = 0.565; mean CPM = 93.43; cytochrome c, somatic" ID="ID_381810956" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1934126008" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000040219: 1.08-fold Up; FDR = 0.86; PValue = 0.575; mean CPM = 8.818; Uncharacterized protein" ID="ID_1363066664" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_1959200790" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP2: 1.05-fold Up; FDR = 0.906; PValue = 0.667; mean CPM = 12.88; caspase 2, apoptosis-related cysteine peptidase" ID="ID_591729126" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DFFB: 1.05-fold Down; FDR = 0.911; PValue = 0.699; mean CPM = 5.555; DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)" ID="ID_178251446" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF21: 1.07-fold Down; FDR = 0.922; PValue = 0.726; mean CPM = 6.488; tumor necrosis factor receptor superfamily, member 21" ID="ID_996086906" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FASLG: 1.2-fold Down; FDR = 0.941; PValue = 0.757; mean CPM = 0.8088; Fas ligand (TNF superfamily, member 6)" ID="ID_1591827676" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BBC3: 1.04-fold Down; FDR = 0.948; PValue = 0.77; mean CPM = 7.586; BCL2 binding component 3" ID="ID_161002500" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000009289: 1.07-fold Up; FDR = 0.963; PValue = 0.798; mean CPM = 2.536; Uncharacterized protein" ID="ID_1678446151" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K4: 1.08-fold Down; FDR = 0.995; PValue = 0.849; mean CPM = 1.007; Uncharacterized protein" ID="ID_842378426" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP9: 1.01-fold Up; FDR = 1; PValue = 0.908; mean CPM = 19.86; caspase 9, apoptosis-related cysteine peptidase" ID="ID_1798343290" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_1478180803" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Notch Signaling Pathway (WP268:Rev45531): FDR = 4.04e-09, PValue = 4.51e-10" ID="ID_1875268048" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="DTX3L: 10.3-fold Up; FDR = 1.64e-26; PValue = 5.8e-30; mean CPM = 115.8; deltex 3-like (Drosophila)" ID="ID_310669345" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RBPJ: 2.84-fold Up; FDR = 1.11e-14; PValue = 1.22e-16; mean CPM = 158.0; recombination signal binding protein for immunoglobulin kappa J region" ID="ID_575798330" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOTCH3: 6.31-fold Down; FDR = 2.33e-13; PValue = 3.29e-15; mean CPM = 185.7; Notch homolog 3 (Drosophila)" ID="ID_717092623" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NUMBL: 2.15-fold Down; FDR = 2.64e-11; PValue = 6.08e-13; mean CPM = 22.15; numb homolog (Drosophila)-like" ID="ID_721640185" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAG1: 2.62-fold Down; FDR = 3.16e-08; PValue = 1.56e-09; mean CPM = 175.2; jagged 1" ID="ID_182933365" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LFNG: 2.87-fold Down; FDR = 6.77e-07; PValue = 4.65e-08; mean CPM = 5.261; LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase" ID="ID_1469753187" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HES1: 2.4-fold Down; FDR = 5.84e-06; PValue = 5.13e-07; mean CPM = 75.36; hairy and enhancer of split 1, (Drosophila)" ID="ID_993285154" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000009315: 1.44-fold Down; FDR = 4.44e-05; PValue = 4.94e-06; mean CPM = 22.79" ID="ID_1121667660" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADAM17: 1.32-fold Up; FDR = 0.00063; PValue = 9.95e-05; mean CPM = 118.8; ADAM metallopeptidase domain 17" ID="ID_157455768" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APH1B: 1.39-fold Up; FDR = 0.000776; PValue = 0.000126; mean CPM = 17.84; anterior pharynx defective 1 homolog B (C. elegans)" ID="ID_1989143140" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DVL3: 1.29-fold Down; FDR = 0.00157; PValue = 0.00028; mean CPM = 67.95; dishevelled, dsh homolog 3 (Drosophila)" ID="ID_480430698" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOTCH1: 1.44-fold Down; FDR = 0.0032; PValue = 0.000634; mean CPM = 32.99; Notch homolog 1, translocation-associated (Drosophila)" ID="ID_1264182118" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTBP1: 1.23-fold Down; FDR = 0.0119; PValue = 0.00287; mean CPM = 100.6; C-terminal binding protein 1" ID="ID_1180207162" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DTX4: 3.25-fold Down; FDR = 0.0142; PValue = 0.00352; mean CPM = 1.542; deltex homolog 4 (Drosophila)" ID="ID_1677128858" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC1: 1.25-fold Up; FDR = 0.0159; PValue = 0.00403; mean CPM = 27.51; histone deacetylase 1" ID="ID_1084584841" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTBP2: 1.23-fold Up; FDR = 0.0166; PValue = 0.00423; mean CPM = 49.75; C-terminal binding protein 2" ID="ID_480051927" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAML1: 1.23-fold Down; FDR = 0.0266; PValue = 0.00733; mean CPM = 45.38; mastermind-like 1 (Drosophila)" ID="ID_1606992303" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCSTN: 1.21-fold Up; FDR = 0.0284; PValue = 0.0079; mean CPM = 205.1; nicastrin" ID="ID_1679204542" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DTX1: 2.82-fold Down; FDR = 0.0473; PValue = 0.0144; mean CPM = 0.9361; deltex homolog 1 (Drosophila)" ID="ID_1900890742" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RFNG: 1.19-fold Down; FDR = 0.0548; PValue = 0.0171; mean CPM = 46.28; RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase" ID="ID_1176459164" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DLL1: 1.66-fold Up; FDR = 0.0898; PValue = 0.0308; mean CPM = 2.702; delta-like 1 (Drosophila)" ID="ID_1530699228" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC2: 1.15-fold Up; FDR = 0.115; PValue = 0.0414; mean CPM = 93.64; histone deacetylase 2" ID="ID_626805742" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DLL4: 1.82-fold Down; FDR = 0.2; PValue = 0.0824; mean CPM = 1.928; delta-like 4 (Drosophila)" ID="ID_1538963136" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSEN1: 1.12-fold Up; FDR = 0.233; PValue = 0.0992; mean CPM = 62.12; presenilin 1" ID="ID_142277174" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MFNG: 1.91-fold Down; FDR = 0.269; PValue = 0.118; mean CPM = 1.078; MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase" ID="ID_693826634" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSEN2: 1.11-fold Down; FDR = 0.445; PValue = 0.222; mean CPM = 23.33; Uncharacterized protein" ID="ID_1020449622" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAG2: 1.26-fold Down; FDR = 0.511; PValue = 0.266; mean CPM = 3.134; Delta-like protein" ID="ID_996559347" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOTCH2: 1.09-fold Down; FDR = 0.514; PValue = 0.268; mean CPM = 795.0; Notch homolog 2 (Drosophila)" ID="ID_803216230" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KAT2A: 1.08-fold Up; FDR = 0.579; PValue = 0.315; mean CPM = 30.51; K(lysine) acetyltransferase 2A" ID="ID_719559004" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KAT2B: 1.13-fold Up; FDR = 0.663; PValue = 0.378; mean CPM = 11.06; Uncharacterized protein" ID="ID_828605051" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTCRA: 1.99-fold Down; FDR = 0.68; PValue = 0.391; mean CPM = 0.8703; pre T-cell antigen receptor alpha" ID="ID_1393864979" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DTX2: 1.08-fold Down; FDR = 0.699; PValue = 0.407; mean CPM = 21.72; deltex homolog 2 (Drosophila)" ID="ID_516269192" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DVL2: 1.06-fold Up; FDR = 0.708; PValue = 0.414; mean CPM = 30.54; dishevelled, dsh homolog 2 (Drosophila)" ID="ID_1290567837" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RBPJL: 1.23-fold Up; FDR = 0.728; PValue = 0.43; mean CPM = 2.226; recombination signal binding protein for immunoglobulin kappa J region-like" ID="ID_776690724" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DLL3: 1.09-fold Down; FDR = 0.808; PValue = 0.504; mean CPM = 5.871; delta-like 3 (Drosophila)" ID="ID_1812003909" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APH1A: 1.05-fold Up; FDR = 0.828; PValue = 0.529; mean CPM = 85.70; anterior pharynx defective 1 homolog A (C. elegans)" ID="ID_1956463497" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_482701875" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NUMB: 1.03-fold Up; FDR = 0.909; PValue = 0.687; mean CPM = 60.96; numb homolog (Drosophila)" ID="ID_824952805" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTBP2: 1.24-fold Up; FDR = 0.934; PValue = 0.746; mean CPM = 0.8168; C-terminal binding protein 2" ID="ID_370704014" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KCNJ5: 1.16-fold Up; FDR = 0.937; PValue = 0.749; mean CPM = 0.8158; potassium inwardly-rectifying channel, subfamily J, member 5" ID="ID_892468359" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREBBP: 1.01-fold Down; FDR = 0.993; PValue = 0.847; mean CPM = 137.7; CREB binding protein" ID="ID_1208247665" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="NOD pathway (WP1433:Rev45352): FDR = 4.04e-09, PValue = 4.63e-10" ID="ID_1128549961" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="AIM2: 7.87-fold Up; FDR = 4.34e-20; PValue = 1.57e-22; mean CPM = 34.80; absent in melanoma 2" ID="ID_1196795826" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP5: 68-fold Up; FDR = 3.54e-19; PValue = 1.64e-21; mean CPM = 7.240; caspase 5, apoptosis-related cysteine peptidase" ID="ID_443546371" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_571191944" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK2: 3.75-fold Up; FDR = 6.1e-16; PValue = 5.38e-18; mean CPM = 68.21; receptor-interacting serine-threonine kinase 2" ID="ID_273919387" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CARD6: 2.33-fold Up; FDR = 1.15e-12; PValue = 1.89e-14; mean CPM = 30.09; caspase recruitment domain family, member 6" ID="ID_679172670" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CARD8: 2.48-fold Up; FDR = 2.44e-11; PValue = 5.59e-13; mean CPM = 14.84; caspase recruitment domain family, member 8" ID="ID_356908229" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CARD8: 2.02-fold Up; FDR = 1.41e-09; PValue = 4.93e-11; mean CPM = 15.89; caspase recruitment domain family, member 8" ID="ID_385641820" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1794715985" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRDM1: 3.05-fold Up; FDR = 3.55e-08; PValue = 1.78e-09; mean CPM = 8.715; PR domain containing 1, with ZNF domain" ID="ID_1757962146" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLRC4: 6.6-fold Up; FDR = 8.52e-08; PValue = 4.67e-09; mean CPM = 3.347; NLR family, CARD domain containing 4" ID="ID_918310989" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90AA1: 1.41-fold Up; FDR = 4.17e-05; PValue = 4.62e-06; mean CPM = 609.6; heat shock protein 90kDa alpha (cytosolic), class A member 2" ID="ID_47437334" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CARD9: 1.53-fold Up; FDR = 9.57e-05; PValue = 1.18e-05; mean CPM = 16.72; caspase recruitment domain family, member 9" ID="ID_684899446" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOD1: 1.63-fold Up; FDR = 0.000193; PValue = 2.61e-05; mean CPM = 58.36; nucleotide-binding oligomerization domain containing 1" ID="ID_635633905" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SUGT1: 1.35-fold Up; FDR = 0.000193; PValue = 2.61e-05; mean CPM = 54.75; SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)" ID="ID_1598822156" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1655399538" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL18: 1.5-fold Down; FDR = 0.00981; PValue = 0.0023; mean CPM = 6.489; interleukin 18 (interferon-gamma-inducing factor)" ID="ID_548718301" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_24668824" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XIAP: 1.17-fold Up; FDR = 0.177; PValue = 0.0706; mean CPM = 19.21; X-linked inhibitor of apoptosis" ID="ID_1815679302" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACAP1: 1.42-fold Down; FDR = 0.179; PValue = 0.0717; mean CPM = 2.333; ArfGAP with coiled-coil, ankyrin repeat and PH domains 1" ID="ID_759712793" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP7: 1.15-fold Up; FDR = 0.218; PValue = 0.0916; mean CPM = 21.49; caspase 7, apoptosis-related cysteine peptidase" ID="ID_1261568263" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PYCARD: 1.38-fold Down; FDR = 0.241; PValue = 0.103; mean CPM = 3.110; PYD and CARD domain containing" ID="ID_113446673" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLRP3: 1.84-fold Down; FDR = 0.32; PValue = 0.147; mean CPM = 0.9630; NLR family, pyrin domain containing 3" ID="ID_984630653" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COPS6: 1.06-fold Down; FDR = 0.655; PValue = 0.371; mean CPM = 93.74; COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)" ID="ID_1491184077" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_1821891024" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSP90AA1: 1.8-fold Up; FDR = 0.749; PValue = 0.449; mean CPM = 0.8328; heat shock protein 90kDa alpha (cytosolic), class A member 1" ID="ID_597528505" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MEFV: 1.13-fold Up; FDR = 0.813; PValue = 0.51; mean CPM = 6.740; Mediterranean fever" ID="ID_1070957040" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1493079430" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOD2: 1.17-fold Up; FDR = 0.866; PValue = 0.583; mean CPM = 1.911; nucleotide-binding oligomerization domain containing 2" ID="ID_1113458887" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLRP10: 1.48-fold Up; FDR = 0.868; PValue = 0.586; mean CPM = 0.8220; NLR family, pyrin domain containing 10" ID="ID_1191229501" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DUOX2: 1.22-fold Down; FDR = 0.898; PValue = 0.625; mean CPM = 1.000; dual oxidase 2" ID="ID_1347803562" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLRP7: 1.15-fold Down; FDR = 0.906; PValue = 0.672; mean CPM = 0.7909; NLR family, pyrin domain containing 7" ID="ID_1683013832" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_234167838" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP9: 1.01-fold Up; FDR = 1; PValue = 0.908; mean CPM = 19.86; caspase 9, apoptosis-related cysteine peptidase" ID="ID_1178101310" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NLRP4: 1.05-fold Down; FDR = 1; PValue = 0.911; mean CPM = 0.8249; NLR family, pyrin domain containing 4" ID="ID_1282799795" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Inflammatory Response Pathway (WP453:Rev41201): FDR = 4.38e-09, PValue = 5.26e-10" ID="ID_1665380233" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="COL3A1: 20.5-fold Down; FDR = 5.71e-15; PValue = 5.82e-17; mean CPM = 5961; collagen, type III, alpha 1" ID="ID_1951122575" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL1A1: 21.5-fold Down; FDR = 1.13e-13; PValue = 1.5e-15; mean CPM = 15389; collagen, type I, alpha 1" ID="ID_1738820527" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL1A2: 10.7-fold Down; FDR = 3.82e-13; PValue = 5.68e-15; mean CPM = 17923; collagen, type I, alpha 2" ID="ID_724417981" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMC1: 2.28-fold Down; FDR = 6.46e-13; PValue = 1.01e-14; mean CPM = 812.1; laminin, gamma 1 (formerly LAMB2)" ID="ID_894544436" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016591: 4.2-fold Down; FDR = 1.3e-11; PValue = 2.78e-13; mean CPM = 34.90; Uncharacterized protein" ID="ID_1220869175" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016587: 4.92-fold Down; FDR = 1.6e-11; PValue = 3.5e-13; mean CPM = 51.70; Uncharacterized protein" ID="ID_236818305" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THBS3: 1.97-fold Up; FDR = 7.19e-08; PValue = 3.88e-09; mean CPM = 128.6; thrombospondin 3" ID="ID_1424919274" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THBS1: 2.74-fold Down; FDR = 1.68e-06; PValue = 1.28e-07; mean CPM = 25785; thrombospondin 1" ID="ID_265817852" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1B: 2.24-fold Up; FDR = 2.68e-06; PValue = 2.16e-07; mean CPM = 19.44; tumor necrosis factor receptor superfamily, member 1B" ID="ID_1924464964" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMC2: 2.28-fold Down; FDR = 9.83e-06; PValue = 9.24e-07; mean CPM = 16.99; laminin, gamma 2" ID="ID_1572607077" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40: 2.76-fold Up; FDR = 0.00039; PValue = 5.79e-05; mean CPM = 9.139; CD40 molecule, TNF receptor superfamily member 5" ID="ID_649702630" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB2: 1.48-fold Down; FDR = 0.000398; PValue = 5.93e-05; mean CPM = 695.6; laminin, beta 2 (laminin S)" ID="ID_481869104" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FN1: 1.7-fold Down; FDR = 0.0164; PValue = 0.00417; mean CPM = 40317; fibronectin 1" ID="ID_1975377209" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF1A: 1.11-fold Up; FDR = 0.297; PValue = 0.134; mean CPM = 134.7; tumor necrosis factor receptor superfamily, member 1A" ID="ID_918518471" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VTN: 1.19-fold Up; FDR = 0.669; PValue = 0.382; mean CPM = 2.950; vitronectin" ID="ID_1987850242" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL4R: 1.05-fold Down; FDR = 0.803; PValue = 0.499; mean CPM = 193.5; interleukin 4 receptor" ID="ID_1411224576" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZAP70: 1.25-fold Down; FDR = 0.872; PValue = 0.59; mean CPM = 0.8996; zeta-chain (TCR) associated protein kinase 70kDa" ID="ID_1426378691" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_312916969" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL4: 1.27-fold Down; FDR = 0.933; PValue = 0.745; mean CPM = 0.8077; interleukin 4" ID="ID_661697106" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2RA: 1.08-fold Up; FDR = 0.945; PValue = 0.766; mean CPM = 0.8493; interleukin 2 receptor, alpha" ID="ID_937893219" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL5RA: 1.1-fold Up; FDR = 0.958; PValue = 0.791; mean CPM = 0.8108; interleukin 5 receptor, alpha" ID="ID_636898633" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD80: 1.08-fold Up; FDR = 0.971; PValue = 0.812; mean CPM = 1.157; CD80 molecule" ID="ID_786686841" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL5: 1.05-fold Down; FDR = 1; PValue = 0.862; mean CPM = 1.367; interleukin 5 (colony-stimulating factor, eosinophil)" ID="ID_1019331054" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD40LG: 1.01-fold Down; FDR = 1; PValue = 0.982; mean CPM = 0.8653; CD40 ligand" ID="ID_1889316898" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD86: 1.01-fold Down; FDR = 1; PValue = 0.99; mean CPM = 0.8012; CD86 molecule" ID="ID_223624065" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2: 1.03-fold Up; FDR = 1; PValue = 0.998; mean CPM = 0.7974; interleukin 2" ID="ID_149882299" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-4 signaling pathway (WP395:Rev45367): FDR = 4.38e-09, PValue = 5.47e-10" ID="ID_293497038" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_1183910665" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_481961248" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_1754813646" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_1726163399" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRS1: 2.78-fold Up; FDR = 7.67e-09; PValue = 3.19e-10; mean CPM = 26.55; Uncharacterized protein" ID="ID_942388905" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_653865399" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_469056976" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_855723367" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS5: 1.38-fold Up; FDR = 4.45e-05; PValue = 4.96e-06; mean CPM = 88.27; suppressor of cytokine signaling 5" ID="ID_1190458983" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF2: 1.34-fold Up; FDR = 0.000403; PValue = 6.01e-05; mean CPM = 39.83; activating transcription factor 2" ID="ID_808774437" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAD: 1.36-fold Down; FDR = 0.000605; PValue = 9.52e-05; mean CPM = 48.46; BCL2-associated agonist of cell death" ID="ID_223693824" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GATA3: 2.81-fold Up; FDR = 0.000734; PValue = 0.000119; mean CPM = 2.229; GATA binding protein 3" ID="ID_1400492651" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS3: 1.69-fold Up; FDR = 0.000994; PValue = 0.000167; mean CPM = 37.76; suppressor of cytokine signaling 3" ID="ID_1122552182" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFIL3: 1.37-fold Up; FDR = 0.00114; PValue = 0.000196; mean CPM = 50.42; nuclear factor, interleukin 3 regulated" ID="ID_609227106" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK3: 2.31-fold Up; FDR = 0.00186; PValue = 0.000342; mean CPM = 2.154; Janus kinase 3" ID="ID_1726636083" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GAB2: 1.33-fold Down; FDR = 0.00208; PValue = 0.000387; mean CPM = 22.59; GRB2-associated binding protein 2" ID="ID_1506086530" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_738293755" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FES: 1.34-fold Up; FDR = 0.00677; PValue = 0.0015; mean CPM = 22.71; feline sarcoma oncogene" ID="ID_735865850" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYK2: 1.24-fold Down; FDR = 0.0142; PValue = 0.00354; mean CPM = 42.58; tyrosine kinase 2" ID="ID_135807081" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1034945139" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DOK2: 1.76-fold Down; FDR = 0.0214; PValue = 0.00569; mean CPM = 2.236; docking protein 2, 56kDa" ID="ID_1182913324" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_588499569" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INPP5D: 1.88-fold Down; FDR = 0.0276; PValue = 0.00763; mean CPM = 5.690; inositol polyphosphate-5-phosphatase, 145kDa" ID="ID_1479260246" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_836909609" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_866452595" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT6: 1.18-fold Up; FDR = 0.0727; PValue = 0.024; mean CPM = 217.5; signal transducer and activator of transcription 6, interleukin-4 induced" ID="ID_1243049643" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_895831466" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_689221314" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC5: 1.51-fold Down; FDR = 0.134; PValue = 0.0501; mean CPM = 18.55; Baculoviral IAP repeat-containing protein 5 isoform 1; Uncharacterized protein" ID="ID_281367785" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1332558360" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_1841603314" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EP300: 1.11-fold Up; FDR = 0.312; PValue = 0.142; mean CPM = 162.8; E1A binding protein p300" ID="ID_338931055" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK11: 1.16-fold Up; FDR = 0.409; PValue = 0.199; mean CPM = 6.959; mitogen-activated protein kinase 11" ID="ID_1222923778" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_90659409" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_589587185" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_1881526298" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRH1: 1.25-fold Up; FDR = 0.455; PValue = 0.228; mean CPM = 4.779; histamine receptor H1" ID="ID_333165945" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL4R: 1.05-fold Down; FDR = 0.803; PValue = 0.499; mean CPM = 193.5; interleukin 4 receptor" ID="ID_349123144" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CBL: 1.05-fold Down; FDR = 0.824; PValue = 0.524; mean CPM = 51.06; Cas-Br-M (murine) ecotropic retroviral transforming sequence" ID="ID_1756227059" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1648159645" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB1: 1.04-fold Up; FDR = 0.88; PValue = 0.6; mean CPM = 30.80; Uncharacterized protein" ID="ID_1455167525" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL4: 1.27-fold Down; FDR = 0.933; PValue = 0.745; mean CPM = 0.8077; interleukin 4" ID="ID_635805" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Kit receptor signaling pathway (WP304:Rev44883): FDR = 6.91e-09, PValue = 9.1e-10" ID="ID_1730515939" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_1079774799" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_68306726" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5A: 2.28-fold Up; FDR = 6.87e-14; PValue = 8.58e-16; mean CPM = 21.55; signal transducer and activator of transcription 5A" ID="ID_1215313567" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_1366767963" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_1104777875" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1387043403" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1130137808" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_1481442235" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_467720092" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPT: 2.89-fold Down; FDR = 3.14e-05; PValue = 3.34e-06; mean CPM = 2.105; microtubule-associated protein tau" ID="ID_1842890913" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAD: 1.36-fold Down; FDR = 0.000605; PValue = 9.52e-05; mean CPM = 48.46; BCL2-associated agonist of cell death" ID="ID_780031605" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG1: 1.31-fold Down; FDR = 0.00352; PValue = 0.000707; mean CPM = 53.66; phospholipase C, gamma 1" ID="ID_1533141889" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_406484670" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA1: 1.25-fold Down; FDR = 0.0241; PValue = 0.00652; mean CPM = 21.28; ribosomal protein S6 kinase, 90kDa, polypeptide 1" ID="ID_937532477" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_865721759" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INPP5D: 1.88-fold Down; FDR = 0.0276; PValue = 0.00763; mean CPM = 5.690; inositol polyphosphate-5-phosphatase, 145kDa" ID="ID_971294073" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_1805987082" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_442080979" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TEC: 1.65-fold Up; FDR = 0.0729; PValue = 0.0241; mean CPM = 3.190; tec protein tyrosine kinase" ID="ID_192924884" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB7: 1.46-fold Down; FDR = 0.12; PValue = 0.0435; mean CPM = 2.867; Uncharacterized protein" ID="ID_1000748202" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SNAI2: 1.27-fold Up; FDR = 0.127; PValue = 0.0468; mean CPM = 55.60; snail homolog 2 (Drosophila)" ID="ID_1496912161" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KITLG: 1.31-fold Up; FDR = 0.209; PValue = 0.0867; mean CPM = 5.766; KIT ligand" ID="ID_1169537206" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_275444136" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS6: 1.13-fold Up; FDR = 0.248; PValue = 0.107; mean CPM = 30.93; suppressor of cytokine signaling 6" ID="ID_948308510" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TBX2: 1.17-fold Up; FDR = 0.308; PValue = 0.14; mean CPM = 43.84; T-box 2" ID="ID_1187120866" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EP300: 1.11-fold Up; FDR = 0.312; PValue = 0.142; mean CPM = 162.8; E1A binding protein p300" ID="ID_643707845" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2: 1.48-fold Up; FDR = 0.384; PValue = 0.184; mean CPM = 1.344; Uncharacterized protein" ID="ID_1723213782" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DOK1: 1.12-fold Down; FDR = 0.406; PValue = 0.198; mean CPM = 92.16; docking protein 1, 62kDa (downstream of tyrosine kinase 1)" ID="ID_1790934346" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_653928740" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_40615078" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_221216505" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOXO3: 1.08-fold Down; FDR = 0.55; PValue = 0.294; mean CPM = 48.45; forkhead box O3" ID="ID_1977358600" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6: 1.08-fold Up; FDR = 0.584; PValue = 0.318; mean CPM = 892.5; ribosomal protein S6" ID="ID_405053680" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCB: 1.86-fold Up; FDR = 0.727; PValue = 0.43; mean CPM = 0.8705; protein kinase C, beta" ID="ID_425461541" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRK: 1.05-fold Up; FDR = 0.791; PValue = 0.488; mean CPM = 59.92; v-crk sarcoma virus CT10 oncogene homolog (avian)" ID="ID_1144006137" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB10: 1.06-fold Up; FDR = 0.808; PValue = 0.505; mean CPM = 72.84; growth factor receptor-bound protein 10" ID="ID_1806857746" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CBL: 1.05-fold Down; FDR = 0.824; PValue = 0.524; mean CPM = 51.06; Cas-Br-M (murine) ecotropic retroviral transforming sequence" ID="ID_1062438248" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV1: 1.25-fold Down; FDR = 0.858; PValue = 0.572; mean CPM = 0.9515; vav 1 guanine nucleotide exchange factor" ID="ID_1111464167" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1993348749" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB1: 1.04-fold Up; FDR = 0.88; PValue = 0.6; mean CPM = 30.80; Uncharacterized protein" ID="ID_1707687603" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_160586133" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA3: 1.02-fold Up; FDR = 0.982; PValue = 0.829; mean CPM = 58.16; ribosomal protein S6 kinase, 90kDa, polypeptide 3" ID="ID_282508613" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MATK: 1.32-fold Down; FDR = 0.985; PValue = 0.834; mean CPM = 0.8687; megakaryocyte-associated tyrosine kinase" ID="ID_1086175215" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BTK: No Change; FDR = 1; PValue = 0.965; mean CPM = 0.8336; Bruton agammaglobulinemia tyrosine kinase" ID="ID_703783411" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Complement Activation, Classical Pathway (WP545:Rev41148): FDR = 6.91e-09, PValue = 9.35e-10" ID="ID_679584888" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="C4B: 24.3-fold Up; FDR = 1.01e-20; PValue = 3.32e-23; mean CPM = 65.82; Complement C4-B Precursor (Basic complement C4)(C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3) [Contains Complement C4 beta chain;Complement C4-B alpha chain;C4a anaphylatoxin;C4b-B;C4d-B;Complement C4 gamma chain]" ID="ID_295115012" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C2: 4.8-fold Up; FDR = 3.21e-17; PValue = 2.26e-19; mean CPM = 200.3; Uncharacterized protein" ID="ID_1690341468" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C3: 5.35-fold Up; FDR = 5.79e-07; PValue = 3.91e-08; mean CPM = 19.68; complement component 3" ID="ID_443771857" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C5: 2.29-fold Up; FDR = 0.0212; PValue = 0.00561; mean CPM = 1.418; complement component 5" ID="ID_1816303031" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C1QB: 2.62-fold Up; FDR = 0.0887; PValue = 0.0304; mean CPM = 1.092; complement component 1, q subcomponent, B chain" ID="ID_205448698" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C1QC: 2.02-fold Up; FDR = 0.203; PValue = 0.0839; mean CPM = 1.322; complement component 1, q subcomponent, C chain" ID="ID_324006217" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MASP1: 1.46-fold Down; FDR = 0.264; PValue = 0.115; mean CPM = 4.467; mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)" ID="ID_653567176" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C8B: 2.74-fold Up; FDR = 0.396; PValue = 0.192; mean CPM = 0.8553; complement component 8, beta polypeptide" ID="ID_1826447076" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C9: 1.41-fold Up; FDR = 0.505; PValue = 0.262; mean CPM = 1.295; complement component 9" ID="ID_1556496378" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C6: 1.72-fold Down; FDR = 0.856; PValue = 0.57; mean CPM = 0.8334; complement component 6" ID="ID_561721304" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C8A: 1.06-fold Up; FDR = 0.968; PValue = 0.808; mean CPM = 0.8260; complement component 8, alpha polypeptide" ID="ID_1405207822" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C7: 1.11-fold Up; FDR = 1; PValue = 0.883; mean CPM = 0.8197; complement component 7" ID="ID_500767389" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Muscle cell TarBase (WP2005:Rev44926): FDR = 7.82e-09, PValue = 1.11e-09" ID="ID_1306816786" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="MOV10: 3.25-fold Up; FDR = 3.99e-24; PValue = 3.94e-27; mean CPM = 132.5; Mov10, Moloney leukemia virus 10, homolog (mouse)" ID="ID_1733767712" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADAR: 2.84-fold Up; FDR = 8.44e-21; PValue = 2.66e-23; mean CPM = 291.8; adenosine deaminase, RNA-specific" ID="ID_648567485" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSF1: 7.34-fold Up; FDR = 4.6e-20; PValue = 1.69e-22; mean CPM = 149.8; colony stimulating factor 1 (macrophage)" ID="ID_654461752" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BACE1: 2.47-fold Down; FDR = 5.34e-16; PValue = 4.61e-18; mean CPM = 93.58; beta-site APP-cleaving enzyme 1" ID="ID_768274442" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP6V0A1: 2.41-fold Down; FDR = 1.81e-15; PValue = 1.67e-17; mean CPM = 68.72; ATPase, H+ transporting, lysosomal V0 subunit a1" ID="ID_200651066" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SDCBP: 2.11-fold Up; FDR = 2.04e-15; PValue = 1.89e-17; mean CPM = 226.9; Syntenin-1 isoform 1; Uncharacterized protein" ID="ID_580237614" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL3A1: 20.5-fold Down; FDR = 5.71e-15; PValue = 5.82e-17; mean CPM = 5961; collagen, type III, alpha 1" ID="ID_350352618" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GPD2: 2.11-fold Up; FDR = 1.4e-14; PValue = 1.58e-16; mean CPM = 142.3; glycerol-3-phosphate dehydrogenase 2 (mitochondrial)" ID="ID_834813149" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPARC: 6.27-fold Down; FDR = 1.51e-14; PValue = 1.73e-16; mean CPM = 4075; secreted protein, acidic, cysteine-rich (osteonectin)" ID="ID_1883454769" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL1A1: 21.5-fold Down; FDR = 1.13e-13; PValue = 1.5e-15; mean CPM = 15389; collagen, type I, alpha 1" ID="ID_351986508" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFAIP2: 3.61-fold Up; FDR = 1.42e-13; PValue = 1.95e-15; mean CPM = 54.70; tumor necrosis factor, alpha-induced protein 2" ID="ID_1888840085" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000036781: 2.4-fold Down; FDR = 1.7e-13; PValue = 2.35e-15; mean CPM = 342.5; Uncharacterized protein" ID="ID_1172603334" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MET: 2.57-fold Up; FDR = 3.56e-13; PValue = 5.22e-15; mean CPM = 242.4; Macaca mulatta met proto-oncogene (hepatocyte growth factor receptor) (MET), mRNA." ID="ID_1514471455" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL1A2: 10.7-fold Down; FDR = 3.82e-13; PValue = 5.68e-15; mean CPM = 17923; collagen, type I, alpha 2" ID="ID_1719284112" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF2R: 2.41-fold Down; FDR = 4.2e-13; PValue = 6.32e-15; mean CPM = 245.2; insulin-like growth factor 2 receptor" ID="ID_166834929" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDLIM7: 2.02-fold Down; FDR = 4.87e-13; PValue = 7.39e-15; mean CPM = 284.3; PDZ and LIM domain 7 (enigma)" ID="ID_978027297" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMC1: 2.28-fold Down; FDR = 6.46e-13; PValue = 1.01e-14; mean CPM = 812.1; laminin, gamma 1 (formerly LAMB2)" ID="ID_394587496" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SNX6: 1.88-fold Up; FDR = 2.14e-12; PValue = 3.75e-14; mean CPM = 91.06; sorting nexin 6" ID="ID_1256032691" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PANX1: 1.9-fold Up; FDR = 2.67e-12; PValue = 4.81e-14; mean CPM = 29.18; pannexin 1" ID="ID_1299920217" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATG9A: 1.77-fold Down; FDR = 1.17e-11; PValue = 2.46e-13; mean CPM = 69.44; ATG9 autophagy related 9 homolog A (S. cerevisiae)" ID="ID_402287470" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC7A6: 1.85-fold Down; FDR = 1.29e-11; PValue = 2.75e-13; mean CPM = 27.57; solute carrier family 7 (cationic amino acid transporter, y+ system), member 6" ID="ID_531832701" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BRPF3: 2-fold Down; FDR = 4.77e-11; PValue = 1.17e-12; mean CPM = 36.05; bromodomain and PHD finger containing, 3" ID="ID_1073247536" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DNMT3A: 1.93-fold Down; FDR = 6.31e-11; PValue = 1.58e-12; mean CPM = 20.49; DNA (cytosine-5-)-methyltransferase 3 alpha" ID="ID_91297141" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PKN2: 1.67-fold Up; FDR = 6.49e-11; PValue = 1.64e-12; mean CPM = 64.77; protein kinase N2" ID="ID_1871473581" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SRF: 1.69-fold Down; FDR = 8.07e-11; PValue = 2.06e-12; mean CPM = 34.61; serum response factor (c-fos serum response element-binding transcription factor)" ID="ID_576467131" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MRC2: 2.12-fold Down; FDR = 1.81e-10; PValue = 5.07e-12; mean CPM = 772.3; mannose receptor, C type 2" ID="ID_1588300014" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RBMS1: 1.63-fold Up; FDR = 2.56e-10; PValue = 7.56e-12; mean CPM = 124.1; RNA binding motif, single stranded interacting protein 1" ID="ID_684627587" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AC137834.2: 2.11-fold Down; FDR = 3.29e-10; PValue = 9.87e-12; mean CPM = 1681; Prolow-density lipoprotein receptor-related protein 1 Precursor (LRP-1)(Alpha-2-macroglobulin receptor)(A2MR)(Apolipoprotein E receptor)(APOER)(CD91 antigen) [Contains Low-density lipoprotein receptor-related protein 1 85 kDa subunit(LRP-85);Low-den /.../ipoprotein receptor-related protein 1 515 kDa subunit(LRP-515);Low-density lipoprotein receptor-related protein 1 intracellular domain(LRPICD)]" ID="ID_1243848094" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="P4HA2: 2.27-fold Down; FDR = 3.92e-10; PValue = 1.2e-11; mean CPM = 511.5; prolyl 4-hydroxylase, alpha polypeptide II" ID="ID_1247694414" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPRF: 2.51-fold Down; FDR = 5.51e-10; PValue = 1.77e-11; mean CPM = 184.0; protein tyrosine phosphatase, receptor type, F" ID="ID_338452938" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA2: 2.84-fold Up; FDR = 7.38e-10; PValue = 2.42e-11; mean CPM = 176.3; integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)" ID="ID_1858267858" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGFR: 1.84-fold Up; FDR = 6.71e-09; PValue = 2.77e-10; mean CPM = 68.58; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)" ID="ID_897243044" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRS1: 2.78-fold Up; FDR = 7.67e-09; PValue = 3.19e-10; mean CPM = 26.55; Uncharacterized protein" ID="ID_1610540128" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF2: 2.42-fold Up; FDR = 9.98e-09; PValue = 4.31e-10; mean CPM = 134.8; fibroblast growth factor 2 (basic)" ID="ID_510379526" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1B: 1.64-fold Up; FDR = 1.22e-08; PValue = 5.39e-10; mean CPM = 32.96; Cyclin-dependent kinase inhibitor 1B; Uncharacterized protein" ID="ID_1719119564" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TPM4: 1.8-fold Down; FDR = 1.34e-08; PValue = 5.96e-10; mean CPM = 1400; tropomyosin 4" ID="ID_1522127794" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BET1: 1.71-fold Up; FDR = 1.6e-08; PValue = 7.28e-10; mean CPM = 23.38; Uncharacterized protein" ID="ID_736161746" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SCYL1: 1.55-fold Down; FDR = 1.88e-08; PValue = 8.75e-10; mean CPM = 136.7; SCY1-like 1 (S. cerevisiae)" ID="ID_1622583764" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDCP1: 2.18-fold Up; FDR = 2.98e-08; PValue = 1.46e-09; mean CPM = 134.3; CUB domain containing protein 1" ID="ID_1063298280" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EZH2: 2.05-fold Up; FDR = 4.94e-08; PValue = 2.57e-09; mean CPM = 24.23; enhancer of zeste homolog 2 (Drosophila)" ID="ID_572460561" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHOC2: 1.55-fold Up; FDR = 5.07e-08; PValue = 2.65e-09; mean CPM = 58.53; soc-2 suppressor of clear homolog (C. elegans)" ID="ID_1658732510" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RB1: 1.65-fold Up; FDR = 6.01e-08; PValue = 3.2e-09; mean CPM = 59.24; retinoblastoma 1" ID="ID_1445102781" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ESR1: 5.04-fold Up; FDR = 6.62e-08; PValue = 3.55e-09; mean CPM = 2.845; estrogen receptor 1" ID="ID_516427047" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PGRMC1: 1.49-fold Up; FDR = 2.86e-07; PValue = 1.79e-08; mean CPM = 67.51; progesterone receptor membrane component 1" ID="ID_893672063" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PODXL: 4.78-fold Up; FDR = 5.61e-07; PValue = 3.77e-08; mean CPM = 2.315; podocalyxin-like" ID="ID_1507670776" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AARSD1: 1.59-fold Down; FDR = 7.9e-07; PValue = 5.53e-08; mean CPM = 19.40; alanyl-tRNA synthetase domain containing 1" ID="ID_678584400" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACP2: 1.49-fold Up; FDR = 9.22e-07; PValue = 6.59e-08; mean CPM = 58.72; acid phosphatase 2, lysosomal" ID="ID_1939271918" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GAK: 1.46-fold Down; FDR = 9.29e-07; PValue = 6.67e-08; mean CPM = 90.22; cyclin G associated kinase" ID="ID_1085164669" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CORO1C: 1.47-fold Down; FDR = 1.18e-06; PValue = 8.66e-08; mean CPM = 186.3; Coronin" ID="ID_22911854" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THBS1: 2.74-fold Down; FDR = 1.68e-06; PValue = 1.28e-07; mean CPM = 25785; thrombospondin 1" ID="ID_98261659" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000002068: 1.63-fold Down; FDR = 2.68e-06; PValue = 2.15e-07; mean CPM = 20.88" ID="ID_68929024" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BACH1: 1.69-fold Up; FDR = 3.53e-06; PValue = 2.94e-07; mean CPM = 503.5; BTB and CNC homology 1, basic leucine zipper transcription factor 1" ID="ID_1386232951" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARHGDIA: 1.49-fold Down; FDR = 3.61e-06; PValue = 3.01e-07; mean CPM = 257.2; Rho GDP dissociation inhibitor (GDI) alpha" ID="ID_1105224415" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NF2: 1.44-fold Down; FDR = 4.19e-06; PValue = 3.54e-07; mean CPM = 50.56; Uncharacterized protein" ID="ID_211344684" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFRD1: 1.57-fold Up; FDR = 5.76e-06; PValue = 5.05e-07; mean CPM = 71.59; interferon-related developmental regulator 1" ID="ID_1741450761" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HES1: 2.4-fold Down; FDR = 5.84e-06; PValue = 5.13e-07; mean CPM = 75.36; hairy and enhancer of split 1, (Drosophila)" ID="ID_1503963635" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMED3: 1.49-fold Down; FDR = 7.47e-06; PValue = 6.8e-07; mean CPM = 282.0; transmembrane emp24 protein transport domain containing 3" ID="ID_699862818" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000029607: 1.58-fold Up; FDR = 8.43e-06; PValue = 7.8e-07; mean CPM = 15.14; Uncharacterized protein" ID="ID_1938828589" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPIB: 1.45-fold Down; FDR = 8.64e-06; PValue = 8.03e-07; mean CPM = 806.4; peptidylprolyl isomerase B (cyclophilin B)" ID="ID_1381020701" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014164: 1.53-fold Up; FDR = 9.48e-06; PValue = 8.87e-07; mean CPM = 21.02; Uncharacterized protein" ID="ID_1046106886" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMC2: 2.28-fold Down; FDR = 9.83e-06; PValue = 9.24e-07; mean CPM = 16.99; laminin, gamma 2" ID="ID_1816224905" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PHLDB2: 1.45-fold Down; FDR = 1.07e-05; PValue = 1.01e-06; mean CPM = 341.6; pleckstrin homology-like domain, family B, member 2" ID="ID_207735431" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CPOX: 1.54-fold Up; FDR = 1.59e-05; PValue = 1.58e-06; mean CPM = 24.79; coproporphyrinogen oxidase" ID="ID_87560357" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ANAPC1: 1.54-fold Down; FDR = 1.66e-05; PValue = 1.66e-06; mean CPM = 59.91; anaphase promoting complex subunit 1" ID="ID_1959955100" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KCNQ1: 3.89-fold Down; FDR = 1.77e-05; PValue = 1.78e-06; mean CPM = 1.716; potassium voltage-gated channel, KQT-like subfamily, member 1" ID="ID_1087809379" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP6V1C1: 1.45-fold Up; FDR = 2.14e-05; PValue = 2.18e-06; mean CPM = 43.90; ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1" ID="ID_1983494204" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT5A: 1.65-fold Down; FDR = 2.5e-05; PValue = 2.59e-06; mean CPM = 136.4; wingless-type MMTV integration site family, member 5A" ID="ID_1386304437" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYO1E: 1.54-fold Down; FDR = 3.16e-05; PValue = 3.37e-06; mean CPM = 330.9; myosin IE" ID="ID_1620207973" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLK1: 2.25-fold Down; FDR = 3.23e-05; PValue = 3.46e-06; mean CPM = 27.29; polo-like kinase 1 (Drosophila)" ID="ID_217164699" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNG1: 1.38-fold Up; FDR = 6.77e-05; PValue = 8.01e-06; mean CPM = 149.9; cyclin G1" ID="ID_234205284" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HMOX1: 1.94-fold Up; FDR = 7.83e-05; PValue = 9.42e-06; mean CPM = 15.01; heme oxygenase (decycling) 1" ID="ID_1722376826" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000034432: 1.4-fold Up; FDR = 8.68e-05; PValue = 1.05e-05; mean CPM = 34.27; Tubulin-specific chaperone A; Uncharacterized protein" ID="ID_403039068" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GJA1: 1.71-fold Up; FDR = 0.000117; PValue = 1.47e-05; mean CPM = 2600; gap junction protein, alpha 1, 43kDa" ID="ID_146996349" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMEM109: 1.4-fold Down; FDR = 0.000118; PValue = 1.49e-05; mean CPM = 78.40; transmembrane protein 109" ID="ID_854613441" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDCD4: 1.38-fold Up; FDR = 0.000119; PValue = 1.5e-05; mean CPM = 39.33; programmed cell death 4 (neoplastic transformation inhibitor)" ID="ID_1303058895" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ANPEP: 2.06-fold Down; FDR = 0.000149; PValue = 1.95e-05; mean CPM = 9.629; alanyl (membrane) aminopeptidase" ID="ID_1843031029" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSRP1: 1.59-fold Down; FDR = 0.000168; PValue = 2.23e-05; mean CPM = 630.6; cysteine and glycine-rich protein 1" ID="ID_1828617881" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARF4: 1.35-fold Down; FDR = 0.000178; PValue = 2.38e-05; mean CPM = 179.9; ADP-ribosylation factor 4" ID="ID_1062753537" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTRR: 1.38-fold Up; FDR = 0.000187; PValue = 2.52e-05; mean CPM = 32.85; 5-methyltetrahydrofolate-homocysteine methyltransferase reductase" ID="ID_1655277550" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHD1: 1.35-fold Up; FDR = 0.000225; PValue = 3.11e-05; mean CPM = 82.41; chromodomain helicase DNA binding protein 1" ID="ID_1881633507" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SFXN1: 1.45-fold Down; FDR = 0.000251; PValue = 3.53e-05; mean CPM = 25.99; sideroflexin 1" ID="ID_762187200" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP6V0E1: 1.38-fold Up; FDR = 0.000282; PValue = 4.02e-05; mean CPM = 138.5; ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1" ID="ID_409675665" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP3CA: 1.55-fold Up; FDR = 0.0003; PValue = 4.32e-05; mean CPM = 40.21; protein phosphatase 3, catalytic subunit, alpha isozyme" ID="ID_945737539" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDLIM5: 1.52-fold Down; FDR = 0.000341; PValue = 4.98e-05; mean CPM = 521.2; PDZ and LIM domain 5" ID="ID_958768003" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC25A1: 1.35-fold Down; FDR = 0.000363; PValue = 5.35e-05; mean CPM = 37.11; solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1" ID="ID_1537784107" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FNDC3A: 1.33-fold Up; FDR = 0.000492; PValue = 7.51e-05; mean CPM = 145.6; fibronectin type III domain containing 3A" ID="ID_1104710169" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMC1A: 1.33-fold Down; FDR = 0.000521; PValue = 8.03e-05; mean CPM = 42.68; structural maintenance of chromosomes 1A" ID="ID_863839324" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NRP1: 1.48-fold Up; FDR = 0.000563; PValue = 8.76e-05; mean CPM = 54.61; neuropilin 1" ID="ID_1483104188" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD3: 1.38-fold Up; FDR = 0.000573; PValue = 8.94e-05; mean CPM = 114.9; SMAD family member 3" ID="ID_1167534231" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LUZP1: 1.32-fold Down; FDR = 0.000613; PValue = 9.65e-05; mean CPM = 137.5; leucine zipper protein 1" ID="ID_181696765" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AMIGO2: 2.39-fold Down; FDR = 0.000639; PValue = 0.000101; mean CPM = 22.90; adhesion molecule with Ig-like domain 2" ID="ID_699144324" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FNDC3B: 1.32-fold Down; FDR = 0.000691; PValue = 0.000111; mean CPM = 260.1; fibronectin type III domain containing 3B" ID="ID_711036508" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYR61: 1.38-fold Down; FDR = 0.000719; PValue = 0.000116; mean CPM = 1035; cysteine-rich, angiogenic inducer, 61" ID="ID_506749467" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033454: 1.33-fold Down; FDR = 0.00107; PValue = 0.000183; mean CPM = 1120; Pyruvate kinase" ID="ID_157714001" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C1QBP: 1.36-fold Up; FDR = 0.00107; PValue = 0.000183; mean CPM = 83.61; complement component 1, q subcomponent binding protein" ID="ID_1538630275" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DOCK5: 1.3-fold Down; FDR = 0.00111; PValue = 0.00019; mean CPM = 133.4; dedicator of cytokinesis 5" ID="ID_381797917" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NT5E: 1.42-fold Up; FDR = 0.00145; PValue = 0.000258; mean CPM = 199.3; 5'-nucleotidase, ecto (CD73)" ID="ID_1612449850" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WDFY1: 1.3-fold Up; FDR = 0.00145; PValue = 0.000258; mean CPM = 69.31; WD repeat and FYVE domain containing 1" ID="ID_1075781207" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC38A5: 1.67-fold Down; FDR = 0.00172; PValue = 0.000313; mean CPM = 18.69; solute carrier family 38, member 5" ID="ID_748080502" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC4A7: 1.34-fold Down; FDR = 0.0018; PValue = 0.00033; mean CPM = 63.32; Uncharacterized protein" ID="ID_602479561" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC9A3R2: 1.35-fold Up; FDR = 0.00193; PValue = 0.000358; mean CPM = 93.48; solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2" ID="ID_683124741" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAD23B: 1.34-fold Up; FDR = 0.00235; PValue = 0.000445; mean CPM = 210.1; RAD23 homolog B (S. cerevisiae)" ID="ID_1226170346" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LRRC8A: 1.3-fold Down; FDR = 0.00256; PValue = 0.000491; mean CPM = 74.42; leucine rich repeat containing 8 family, member A" ID="ID_1909123329" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DHX15: 1.28-fold Up; FDR = 0.00298; PValue = 0.000582; mean CPM = 152.3; DEAH (Asp-Glu-Ala-His) box polypeptide 15" ID="ID_1725682377" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRPEL2: 1.39-fold Up; FDR = 0.00298; PValue = 0.000584; mean CPM = 21.71; GrpE-like 2, mitochondrial (E. coli)" ID="ID_1160513160" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOTCH1: 1.44-fold Down; FDR = 0.0032; PValue = 0.000634; mean CPM = 32.99; Notch homolog 1, translocation-associated (Drosophila)" ID="ID_734875430" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTHFD2: 1.37-fold Up; FDR = 0.00326; PValue = 0.000646; mean CPM = 158.6; methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase" ID="ID_99561078" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDE3A: 1.53-fold Down; FDR = 0.00339; PValue = 0.000678; mean CPM = 65.10; phosphodiesterase 3A, cGMP-inhibited" ID="ID_560269056" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSAT1: 1.79-fold Up; FDR = 0.00355; PValue = 0.000715; mean CPM = 220.2; Uncharacterized protein" ID="ID_1724264903" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB4: 1.66-fold Down; FDR = 0.00369; PValue = 0.000748; mean CPM = 5.291; integrin, beta 4" ID="ID_594810625" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STX7: 1.29-fold Up; FDR = 0.00375; PValue = 0.000762; mean CPM = 40.57; Syntaxin-7; Uncharacterized protein" ID="ID_1940771659" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SYPL1: 1.29-fold Up; FDR = 0.00402; PValue = 0.000826; mean CPM = 28.95; synaptophysin-like 1" ID="ID_501873672" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000023633: 2.4-fold Up; FDR = 0.00403; PValue = 0.00083; mean CPM = 1.597; Uncharacterized protein" ID="ID_932289022" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TDG: 1.3-fold Down; FDR = 0.00422; PValue = 0.000874; mean CPM = 24.07; thymine-DNA glycosylase" ID="ID_1910963526" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF2C3: 1.29-fold Up; FDR = 0.00423; PValue = 0.000876; mean CPM = 30.33; eukaryotic translation initiation factor 2C, 3" ID="ID_332589049" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARID1A: 1.27-fold Down; FDR = 0.00443; PValue = 0.000925; mean CPM = 100.8; AT rich interactive domain 1A (SWI-like)" ID="ID_1589974721" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC25A24: 1.27-fold Up; FDR = 0.00467; PValue = 0.000982; mean CPM = 71.95; solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24" ID="ID_1936195636" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SEC62: 1.26-fold Up; FDR = 0.00511; PValue = 0.00109; mean CPM = 81.14; SEC62 homolog (S. cerevisiae)" ID="ID_1837200370" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FAR1: 1.28-fold Up; FDR = 0.00521; PValue = 0.00111; mean CPM = 33.54; fatty acyl CoA reductase 1" ID="ID_1397535091" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC4: 1.38-fold Down; FDR = 0.00526; PValue = 0.00112; mean CPM = 48.60; histone deacetylase 4" ID="ID_1500513912" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="USP1: 1.31-fold Up; FDR = 0.0054; PValue = 0.00116; mean CPM = 39.82; ubiquitin specific peptidase 1" ID="ID_689175149" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VEZT: 1.25-fold Up; FDR = 0.0069; PValue = 0.00153; mean CPM = 74.30; vezatin, adherens junctions transmembrane protein" ID="ID_1768660518" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC1A4: 1.4-fold Down; FDR = 0.00754; PValue = 0.0017; mean CPM = 83.85; solute carrier family 1 (glutamate/neutral amino acid transporter), member 4" ID="ID_134392051" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAB30: 1.38-fold Down; FDR = 0.00805; PValue = 0.00183; mean CPM = 16.45; RAB30, member RAS oncogene family" ID="ID_242075594" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AXL: 1.27-fold Down; FDR = 0.00864; PValue = 0.00199; mean CPM = 898.2; AXL receptor tyrosine kinase" ID="ID_1191291650" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="POLA2: 1.33-fold Down; FDR = 0.00988; PValue = 0.00232; mean CPM = 18.01; polymerase (DNA directed), alpha 2 (70kD subunit)" ID="ID_1270977095" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCOA3: 1.24-fold Up; FDR = 0.0123; PValue = 0.00297; mean CPM = 178.3; nuclear receptor coactivator 3" ID="ID_1433417053" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSD17B12: 1.26-fold Up; FDR = 0.0145; PValue = 0.0036; mean CPM = 51.46; hydroxysteroid (17-beta) dehydrogenase 12" ID="ID_111989288" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RTN4: 1.23-fold Up; FDR = 0.0145; PValue = 0.0036; mean CPM = 165.8; Reticulon" ID="ID_1139270644" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CPNE8: 1.43-fold Up; FDR = 0.0153; PValue = 0.00384; mean CPM = 8.182; copine VIII" ID="ID_649849803" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SNX19: 1.22-fold Down; FDR = 0.0154; PValue = 0.00388; mean CPM = 67.24; sorting nexin 19" ID="ID_1657038823" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HBXIP: 1.24-fold Up; FDR = 0.0155; PValue = 0.00392; mean CPM = 74.39; Uncharacterized protein" ID="ID_1169276923" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LMNB2: 1.32-fold Down; FDR = 0.0162; PValue = 0.00412; mean CPM = 72.73; lamin B2" ID="ID_283357276" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAB27B: 2.09-fold Up; FDR = 0.0173; PValue = 0.00443; mean CPM = 2.962; RAB27B, member RAS oncogene family" ID="ID_1448407914" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADIPOR2: 1.46-fold Down; FDR = 0.0179; PValue = 0.00461; mean CPM = 21.90; adiponectin receptor 2" ID="ID_735252421" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PWP1: 1.22-fold Up; FDR = 0.0184; PValue = 0.00479; mean CPM = 69.91; PWP1 homolog (S. cerevisiae)" ID="ID_331730701" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SYNE1: 1.26-fold Up; FDR = 0.0191; PValue = 0.005; mean CPM = 384.7; spectrin repeat containing, nuclear envelope 1" ID="ID_237041226" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYP1B1: 1.38-fold Down; FDR = 0.0201; PValue = 0.00528; mean CPM = 273.1; cytochrome P450, family 1, subfamily B, polypeptide 1" ID="ID_836350279" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GALNT7: 1.31-fold Up; FDR = 0.0218; PValue = 0.0058; mean CPM = 12.18; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)" ID="ID_1568667880" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FSTL1: 1.23-fold Down; FDR = 0.0219; PValue = 0.00585; mean CPM = 1004; microRNA 198" ID="ID_823249025" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SYNE2: 1.42-fold Up; FDR = 0.0223; PValue = 0.00597; mean CPM = 76.79; spectrin repeat containing, nuclear envelope 2" ID="ID_1234877469" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SNX15: 1.27-fold Down; FDR = 0.023; PValue = 0.00618; mean CPM = 20.98; sorting nexin 15" ID="ID_570261947" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSDE1: 1.22-fold Up; FDR = 0.0231; PValue = 0.0062; mean CPM = 461.0; Uncharacterized protein" ID="ID_555231482" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TXN2: 1.21-fold Down; FDR = 0.026; PValue = 0.00713; mean CPM = 40.77; thioredoxin 2" ID="ID_1111604106" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FADS2: 1.44-fold Down; FDR = 0.0274; PValue = 0.00759; mean CPM = 208.0; fatty acid desaturase 2" ID="ID_268812067" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HIPK3: 1.21-fold Up; FDR = 0.0282; PValue = 0.00784; mean CPM = 123.5; homeodomain interacting protein kinase 3" ID="ID_886070897" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDIPT: 1.21-fold Down; FDR = 0.0297; PValue = 0.00831; mean CPM = 71.76; CDP-diacylglycerol--inositol 3-phosphatidyltransferase" ID="ID_1249192558" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MCL1: 1.2-fold Up; FDR = 0.0335; PValue = 0.00961; mean CPM = 193.8; myeloid cell leukemia sequence 1 (BCL2-related)" ID="ID_1566543184" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SEC23A: 1.2-fold Down; FDR = 0.0358; PValue = 0.0104; mean CPM = 245.8; Sec23 homolog A (S. cerevisiae)" ID="ID_544539651" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAND1: 1.2-fold Up; FDR = 0.0393; PValue = 0.0116; mean CPM = 164.5; cullin-associated and neddylation-dissociated 1" ID="ID_316054294" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NUCB1: 1.21-fold Down; FDR = 0.0393; PValue = 0.0116; mean CPM = 323.6; nucleobindin 1" ID="ID_1599151330" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KRAS: 1.35-fold Down; FDR = 0.0401; PValue = 0.0119; mean CPM = 13.10; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog" ID="ID_1169030828" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZEB1: 1.27-fold Up; FDR = 0.0405; PValue = 0.012; mean CPM = 45.24; zinc finger E-box binding homeobox 1" ID="ID_54026986" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="E2F1: 1.44-fold Down; FDR = 0.0425; PValue = 0.0127; mean CPM = 8.857; E2F transcription factor 1" ID="ID_131564187" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNA13: 1.25-fold Up; FDR = 0.0428; PValue = 0.0128; mean CPM = 15.41; guanine nucleotide binding protein (G protein), alpha 13" ID="ID_617097629" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NXN: 1.19-fold Down; FDR = 0.0457; PValue = 0.0138; mean CPM = 70.27; nucleoredoxin" ID="ID_508302208" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSDL1: 1.29-fold Up; FDR = 0.0468; PValue = 0.0142; mean CPM = 9.092; hydroxysteroid dehydrogenase like 1" ID="ID_994206942" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARID4B: 1.19-fold Up; FDR = 0.0468; PValue = 0.0142; mean CPM = 46.72; AT rich interactive domain 4B (RBP1-like)" ID="ID_866926378" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMEM87A: 1.19-fold Up; FDR = 0.0484; PValue = 0.0148; mean CPM = 86.44; transmembrane protein 87A" ID="ID_59080247" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTNNB1: 1.2-fold Up; FDR = 0.0498; PValue = 0.0153; mean CPM = 558.3; catenin (cadherin-associated protein), beta 1, 88kDa" ID="ID_65099186" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYP51A1: 1.2-fold Down; FDR = 0.0512; PValue = 0.0158; mean CPM = 34.30; cytochrome P450, family 51, subfamily A, polypeptide 1" ID="ID_52782126" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPCS3: 1.23-fold Up; FDR = 0.0634; PValue = 0.0204; mean CPM = 55.68; signal peptidase complex subunit 3 homolog (S. cerevisiae)" ID="ID_843388579" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFBR2: 1.19-fold Up; FDR = 0.0643; PValue = 0.0208; mean CPM = 350.8; transforming growth factor, beta receptor II (70/80kDa)" ID="ID_1100615512" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TTC9C: 1.2-fold Up; FDR = 0.068; PValue = 0.0222; mean CPM = 23.47; tetratricopeptide repeat domain 9C" ID="ID_1726025155" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SEC24A: 1.17-fold Down; FDR = 0.0725; PValue = 0.0239; mean CPM = 88.13; SEC24 family, member A (S. cerevisiae)" ID="ID_1518666250" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD164: 1.17-fold Up; FDR = 0.0745; PValue = 0.0247; mean CPM = 58.11; CD164 molecule, sialomucin" ID="ID_1127327185" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DNAJB1: 1.18-fold Up; FDR = 0.0756; PValue = 0.0252; mean CPM = 33.66; DnaJ (Hsp40) homolog, subfamily B, member 1" ID="ID_861767064" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EHMT1: 1.17-fold Down; FDR = 0.0774; PValue = 0.0259; mean CPM = 58.20; euchromatic histone-lysine N-methyltransferase 1" ID="ID_1283074831" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="METTL7A: 1.32-fold Down; FDR = 0.0808; PValue = 0.0272; mean CPM = 9.508; methyltransferase like 7A" ID="ID_408429359" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SERP1: 1.17-fold Down; FDR = 0.0832; PValue = 0.0282; mean CPM = 113.3; Ribosome-associated membrane protein RAMP4-2; Stress-associated endoplasmic reticulum protein 1; Uncharacterized protein" ID="ID_685335598" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPRJ: 1.17-fold Up; FDR = 0.0865; PValue = 0.0294; mean CPM = 37.56; protein tyrosine phosphatase, receptor type, J" ID="ID_924702342" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPIF: 1.22-fold Down; FDR = 0.0887; PValue = 0.0304; mean CPM = 22.64; peptidylprolyl isomerase F" ID="ID_95106467" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ABCG2: 1.37-fold Down; FDR = 0.0941; PValue = 0.0326; mean CPM = 8.508; ATP-binding cassette, sub-family G (WHITE), member 2" ID="ID_1252574650" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC25A13: 1.23-fold Down; FDR = 0.0998; PValue = 0.035; mean CPM = 11.38; solute carrier family 25 (aspartate/glutamate carrier), member 13" ID="ID_14441039" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ANP32B: 1.23-fold Up; FDR = 0.1; PValue = 0.0352; mean CPM = 12.72; acidic (leucine-rich) nuclear phosphoprotein 32 family, member B" ID="ID_1340615620" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLDN1: 1.57-fold Up; FDR = 0.1; PValue = 0.0352; mean CPM = 7.527; claudin 1" ID="ID_634209206" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND1: 1.17-fold Up; FDR = 0.121; PValue = 0.0443; mean CPM = 867.3; cyclin D1" ID="ID_549593630" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AP3B1: 1.15-fold Up; FDR = 0.125; PValue = 0.0462; mean CPM = 114.4; adaptor-related protein complex 3, beta 1 subunit" ID="ID_644388077" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STRN: 1.15-fold Up; FDR = 0.127; PValue = 0.0468; mean CPM = 43.94; striatin, calmodulin binding protein" ID="ID_41802320" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FAM96A: 1.3-fold Up; FDR = 0.152; PValue = 0.0583; mean CPM = 5.371; family with sequence similarity 96, member A" ID="ID_1507757254" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYLIP: 1.27-fold Down; FDR = 0.163; PValue = 0.0637; mean CPM = 13.73; myosin regulatory light chain interacting protein" ID="ID_1041410353" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZNF622: 1.14-fold Up; FDR = 0.166; PValue = 0.0651; mean CPM = 40.23; zinc finger protein 622" ID="ID_1531936402" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTBP2: 1.18-fold Down; FDR = 0.167; PValue = 0.0653; mean CPM = 15.41; Uncharacterized protein" ID="ID_380783581" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMEM41B: 1.15-fold Up; FDR = 0.167; PValue = 0.0654; mean CPM = 31.62; transmembrane protein 41B" ID="ID_1065669713" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAGT1: 1.14-fold Down; FDR = 0.17; PValue = 0.0674; mean CPM = 86.91; magnesium transporter 1" ID="ID_562991457" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC12A2: 1.16-fold Down; FDR = 0.179; PValue = 0.0714; mean CPM = 21.23; solute carrier family 12 (sodium/potassium/chloride transporters), member 2" ID="ID_1575938525" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPRYD4: 1.21-fold Up; FDR = 0.182; PValue = 0.0729; mean CPM = 9.254; SPRY domain containing 4" ID="ID_1931140191" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTPN: 1.13-fold Up; FDR = 0.185; PValue = 0.0746; mean CPM = 120.1; leucine zipper protein 6" ID="ID_1607042604" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHEB: 1.13-fold Up; FDR = 0.193; PValue = 0.0785; mean CPM = 118.9; Ras homolog enriched in brain" ID="ID_406373635" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WDR82: 1.13-fold Up; FDR = 0.194; PValue = 0.0791; mean CPM = 43.33; WD repeat domain 82" ID="ID_53753457" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHMP2A: 1.13-fold Up; FDR = 0.197; PValue = 0.0805; mean CPM = 122.1; chromatin modifying protein 2A" ID="ID_1502936706" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACAA2: 1.13-fold Up; FDR = 0.198; PValue = 0.0811; mean CPM = 42.36; acetyl-CoA acyltransferase 2" ID="ID_1019421644" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="POLD2: 1.15-fold Down; FDR = 0.21; PValue = 0.0872; mean CPM = 59.57; polymerase (DNA directed), delta 2, regulatory subunit 50kDa" ID="ID_968661632" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="YWHAQ: 1.13-fold Up; FDR = 0.216; PValue = 0.0903; mean CPM = 187.3; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide" ID="ID_1238209314" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHORDC1: 1.13-fold Up; FDR = 0.218; PValue = 0.0912; mean CPM = 40.15; cysteine and histidine-rich domain (CHORD)-containing 1" ID="ID_143398765" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GPAM: 1.18-fold Down; FDR = 0.225; PValue = 0.0948; mean CPM = 31.54; Uncharacterized protein" ID="ID_655632728" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ABHD10: 1.17-fold Up; FDR = 0.227; PValue = 0.0962; mean CPM = 12.94; abhydrolase domain containing 10" ID="ID_66861807" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ERBB2: 1.14-fold Down; FDR = 0.23; PValue = 0.0977; mean CPM = 119.0; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)" ID="ID_760731589" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAI14: 1.13-fold Down; FDR = 0.233; PValue = 0.0989; mean CPM = 323.5; retinoic acid induced 14" ID="ID_1036695082" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAB6A: 1.12-fold Up; FDR = 0.234; PValue = 0.0994; mean CPM = 78.40; RAB6A, member RAS oncogene family" ID="ID_739191528" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RFT1: 1.14-fold Up; FDR = 0.234; PValue = 0.0998; mean CPM = 23.41; RFT1 homolog (S. cerevisiae)" ID="ID_1141267495" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SNAP29: 1.13-fold Up; FDR = 0.239; PValue = 0.102; mean CPM = 28.83; synaptosomal-associated protein, 29kDa" ID="ID_1190379526" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAB34: 1.12-fold Down; FDR = 0.24; PValue = 0.103; mean CPM = 96.35; RAB34, member RAS oncogene family" ID="ID_1096646185" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RDH10: 1.22-fold Up; FDR = 0.27; PValue = 0.119; mean CPM = 17.06; retinol dehydrogenase 10 (all-trans)" ID="ID_1454085496" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC7A11: 1.22-fold Up; FDR = 0.276; PValue = 0.122; mean CPM = 80.96; solute carrier family 7, (cationic amino acid transporter, y+ system) member 11" ID="ID_500500993" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1A: 1.16-fold Down; FDR = 0.28; PValue = 0.124; mean CPM = 363.2; Cyclin-dependent kinase inhibitor 1; Uncharacterized protein" ID="ID_232394400" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RQCD1: 1.12-fold Up; FDR = 0.288; PValue = 0.129; mean CPM = 31.22; RCD1 required for cell differentiation1 homolog (S. pombe)" ID="ID_222952239" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LTN1: 1.11-fold Up; FDR = 0.29; PValue = 0.13; mean CPM = 87.31; listerin E3 ubiquitin protein ligase 1" ID="ID_835162409" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GEMIN7: 1.18-fold Down; FDR = 0.301; PValue = 0.136; mean CPM = 8.388; gem (nuclear organelle) associated protein 7" ID="ID_305253819" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK6: 1.18-fold Down; FDR = 0.301; PValue = 0.136; mean CPM = 26.51; cyclin-dependent kinase 6" ID="ID_379397224" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMED2: 1.11-fold Down; FDR = 0.312; PValue = 0.142; mean CPM = 201.8; transmembrane emp24 domain trafficking protein 2" ID="ID_1025862529" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TH1L: 1.11-fold Down; FDR = 0.315; PValue = 0.144; mean CPM = 56.09; TH1-like (Drosophila)" ID="ID_1768325920" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ELMOD2: 1.16-fold Down; FDR = 0.321; PValue = 0.147; mean CPM = 12.20; ELMO/CED-12 domain containing 2" ID="ID_126533508" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAFAH1B2: 1.11-fold Up; FDR = 0.323; PValue = 0.148; mean CPM = 54.61; platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)" ID="ID_527495159" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC4A10: 1.9-fold Down; FDR = 0.326; PValue = 0.15; mean CPM = 0.8928; Sodium-driven chloride bicarbonate exchanger isoform 2; Uncharacterized protein" ID="ID_1501765674" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DMTF1: 1.11-fold Up; FDR = 0.331; PValue = 0.153; mean CPM = 32.97; cyclin D binding myb-like transcription factor 1" ID="ID_1819108248" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAPG: 1.11-fold Up; FDR = 0.334; PValue = 0.155; mean CPM = 333.3; capping protein (actin filament), gelsolin-like" ID="ID_863619516" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF10B: 1.13-fold Down; FDR = 0.343; PValue = 0.16; mean CPM = 40.59; tumor necrosis factor receptor superfamily, member 10b" ID="ID_1361084392" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSNK1D: 1.1-fold Down; FDR = 0.378; PValue = 0.18; mean CPM = 93.44; casein kinase 1, delta" ID="ID_1304451353" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SH3BGRL3: 1.11-fold Up; FDR = 0.378; PValue = 0.18; mean CPM = 53.14; Uncharacterized protein" ID="ID_1802712123" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2: 1.48-fold Up; FDR = 0.384; PValue = 0.184; mean CPM = 1.344; Uncharacterized protein" ID="ID_1754966368" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COMMD9: 1.11-fold Up; FDR = 0.396; PValue = 0.192; mean CPM = 23.54; COMM domain containing 9" ID="ID_605025111" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AADACL1: 1.15-fold Up; FDR = 0.406; PValue = 0.198; mean CPM = 8.121; neutral cholesterol ester hydrolase 1" ID="ID_147452456" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_879901708" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK12: 1.19-fold Down; FDR = 0.422; PValue = 0.208; mean CPM = 6.569; mitogen-activated protein kinase 12" ID="ID_183015882" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KDELC2: 1.11-fold Up; FDR = 0.461; PValue = 0.232; mean CPM = 32.03; KDEL (Lys-Asp-Glu-Leu) containing 2" ID="ID_1231649274" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CXCL12: 1.27-fold Down; FDR = 0.488; PValue = 0.251; mean CPM = 4.383; chemokine (C-X-C motif) ligand 12" ID="ID_891628721" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLOCK: 1.09-fold Up; FDR = 0.49; PValue = 0.251; mean CPM = 42.77; clock circadian regulator" ID="ID_1302508857" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP1R7: 1.09-fold Down; FDR = 0.491; PValue = 0.253; mean CPM = 35.27; protein phosphatase 1, regulatory subunit 7" ID="ID_1044258726" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYMS: 1.11-fold Up; FDR = 0.494; PValue = 0.254; mean CPM = 71.74; thymidylate synthetase" ID="ID_789589195" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SRPRB: 1.11-fold Down; FDR = 0.498; PValue = 0.257; mean CPM = 73.37; signal recognition particle receptor, B subunit" ID="ID_1470360353" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOTCH2: 1.09-fold Down; FDR = 0.514; PValue = 0.268; mean CPM = 795.0; Notch homolog 2 (Drosophila)" ID="ID_1272038765" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCI: 1.08-fold Up; FDR = 0.518; PValue = 0.271; mean CPM = 47.99; protein kinase C, iota" ID="ID_1224092906" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ASH2L: 1.08-fold Up; FDR = 0.522; PValue = 0.274; mean CPM = 50.16; ash2 (absent, small, or homeotic)-like (Drosophila)" ID="ID_760401235" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TUSC2: 1.09-fold Up; FDR = 0.528; PValue = 0.278; mean CPM = 24.96; tumor suppressor candidate 2" ID="ID_27889436" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SH3BP4: 1.08-fold Up; FDR = 0.533; PValue = 0.281; mean CPM = 168.9; SH3-domain binding protein 4" ID="ID_1830135449" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC25A32: 1.08-fold Down; FDR = 0.553; PValue = 0.296; mean CPM = 36.64; solute carrier family 25, member 32" ID="ID_923370646" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CACNA2D1: 1.13-fold Down; FDR = 0.562; PValue = 0.303; mean CPM = 10.13; calcium channel, voltage-dependent, alpha 2/delta subunit 1" ID="ID_553689162" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MBNL1: 1.08-fold Up; FDR = 0.574; PValue = 0.311; mean CPM = 371.7; muscleblind-like (Drosophila)" ID="ID_1318627190" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TPM2: 1.85-fold Down; FDR = 0.59; PValue = 0.322; mean CPM = 0.8275; tropomyosin 2 (beta)" ID="ID_1210098933" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SRSF9: 1.07-fold Down; FDR = 0.595; PValue = 0.326; mean CPM = 49.60; Uncharacterized protein" ID="ID_1971360249" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKAL1: 1.11-fold Up; FDR = 0.602; PValue = 0.331; mean CPM = 9.302; CDK5 regulatory subunit associated protein 1-like 1" ID="ID_1071106804" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NARG1: 1.07-fold Up; FDR = 0.603; PValue = 0.332; mean CPM = 80.31; N(alpha)-acetyltransferase 15, NatA auxiliary subunit" ID="ID_1828165748" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF2BP1: 1.46-fold Down; FDR = 0.604; PValue = 0.333; mean CPM = 0.9575; insulin-like growth factor 2 mRNA binding protein 1" ID="ID_342896889" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KPNA3: 1.07-fold Up; FDR = 0.638; PValue = 0.358; mean CPM = 36.48; karyopherin alpha 3 (importin alpha 4)" ID="ID_406360131" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TTK: 1.14-fold Up; FDR = 0.67; PValue = 0.383; mean CPM = 11.40; TTK protein kinase" ID="ID_1399514713" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DSG2: 1.25-fold Down; FDR = 0.681; PValue = 0.392; mean CPM = 2.409; desmoglein 2" ID="ID_1692818443" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP2A2: 1.06-fold Down; FDR = 0.705; PValue = 0.411; mean CPM = 361.0; ATPase, Ca++ transporting, cardiac muscle, slow twitch 2" ID="ID_1631447618" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COIL: 1.07-fold Up; FDR = 0.741; PValue = 0.442; mean CPM = 16.95; coilin" ID="ID_214489908" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP53INP1: 1.12-fold Up; FDR = 0.743; PValue = 0.444; mean CPM = 8.273; tumor protein p53 inducible nuclear protein 1" ID="ID_470795950" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="E2F3: 1.08-fold Up; FDR = 0.751; PValue = 0.452; mean CPM = 11.79; E2F transcription factor 3" ID="ID_1002695216" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMEM43: 1.05-fold Down; FDR = 0.783; PValue = 0.48; mean CPM = 121.5; transmembrane protein 43" ID="ID_628991772" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SFRS13A: 1.49-fold Down; FDR = 0.79; PValue = 0.486; mean CPM = 0.8044; splicing factor, arginine/serine-rich 13A" ID="ID_351532214" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMED7-TICAM2: 1.05-fold Down; FDR = 0.796; PValue = 0.493; mean CPM = 150.6; TMED7-TICAM2 readthrough" ID="ID_877517028" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNPNAT1: 1.06-fold Down; FDR = 0.806; PValue = 0.502; mean CPM = 21.70; glucosamine-phosphate N-acetyltransferase 1" ID="ID_826659877" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC38A2: 1.05-fold Up; FDR = 0.808; PValue = 0.504; mean CPM = 193.5; solute carrier family 38, member 2" ID="ID_1978767289" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VSNL1: 1.7-fold Up; FDR = 0.811; PValue = 0.508; mean CPM = 0.8610; visinin-like 1" ID="ID_1800406265" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMED10: 1.05-fold Down; FDR = 0.821; PValue = 0.52; mean CPM = 318.9; transmembrane emp24-like trafficking protein 10 (yeast)" ID="ID_1699912678" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CUL4B: 1.04-fold Up; FDR = 0.836; PValue = 0.541; mean CPM = 53.38; cullin 4B" ID="ID_285638432" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000023221: 1.32-fold Up; FDR = 0.854; PValue = 0.567; mean CPM = 0.7977" ID="ID_698684986" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NUFIP2: 1.04-fold Down; FDR = 0.854; PValue = 0.567; mean CPM = 77.45; nuclear fragile X mental retardation protein interacting protein 2" ID="ID_1780934820" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RARS: 1.04-fold Up; FDR = 0.888; PValue = 0.61; mean CPM = 124.3; arginyl-tRNA synthetase" ID="ID_297979273" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LCLAT1: 1.06-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 8.655; lysocardiolipin acyltransferase 1" ID="ID_1374291033" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000024007: 1.24-fold Up; FDR = 0.898; PValue = 0.622; mean CPM = 0.8140; Uncharacterized protein" ID="ID_1081024864" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TM6SF1: 1.06-fold Up; FDR = 0.898; PValue = 0.623; mean CPM = 8.722; transmembrane 6 superfamily member 1" ID="ID_1551053309" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK7: 1.04-fold Down; FDR = 0.899; PValue = 0.632; mean CPM = 16.93; Uncharacterized protein" ID="ID_234156704" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MPZL1: 1.03-fold Up; FDR = 0.902; PValue = 0.639; mean CPM = 84.36; myelin protein zero-like 1" ID="ID_13822128" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATRX: 1.03-fold Down; FDR = 0.903; PValue = 0.645; mean CPM = 98.18; alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae)" ID="ID_584007874" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HMGA1: 1.08-fold Down; FDR = 0.907; PValue = 0.673; mean CPM = 2.839; Uncharacterized protein" ID="ID_1502209664" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ERG: 1.47-fold Down; FDR = 0.908; PValue = 0.681; mean CPM = 0.8176; v-ets erythroblastosis virus E26 oncogene homolog (avian)" ID="ID_1249135509" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MRPS24: 1.03-fold Down; FDR = 0.909; PValue = 0.684; mean CPM = 36.51; mitochondrial ribosomal protein S24" ID="ID_1826163267" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCL: 1.03-fold Up; FDR = 0.909; PValue = 0.691; mean CPM = 392.4; nucleolin" ID="ID_212189026" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000011953: 1.14-fold Up; FDR = 0.911; PValue = 0.701; mean CPM = 0.7953; Uncharacterized protein" ID="ID_907679899" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SNAP23: 1.02-fold Up; FDR = 0.933; PValue = 0.744; mean CPM = 74.31; synaptosomal-associated protein, 23kDa" ID="ID_409625753" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R4: 1.02-fold Down; FDR = 0.943; PValue = 0.763; mean CPM = 93.45; protein phosphatase 2A activator, regulatory subunit 4" ID="ID_1776349628" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK5RAP3: 1.02-fold Down; FDR = 0.943; PValue = 0.764; mean CPM = 56.54; Uncharacterized protein" ID="ID_1994507308" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNL3L: 1.02-fold Down; FDR = 0.95; PValue = 0.775; mean CPM = 27.41; guanine nucleotide binding protein-like 3 (nucleolar)-like" ID="ID_1093280515" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000018123: 1.02-fold Down; FDR = 0.964; PValue = 0.8; mean CPM = 57.60; Uncharacterized protein" ID="ID_1740388085" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000018123: 1.02-fold Down; FDR = 0.964; PValue = 0.8; mean CPM = 57.60; Uncharacterized protein" ID="ID_1116384820" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAMTA1: 1.28-fold Down; FDR = 0.97; PValue = 0.81; mean CPM = 0.8674; Uncharacterized protein" ID="ID_1535193243" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000013347: 1.15-fold Down; FDR = 0.971; PValue = 0.812; mean CPM = 0.8040; Pyruvate kinase" ID="ID_1399259057" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPLAD1: 1.02-fold Up; FDR = 0.98; PValue = 0.825; mean CPM = 47.79; protein tyrosine phosphatase-like A domain containing 1" ID="ID_242142592" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFIA: 1.05-fold Down; FDR = 0.99; PValue = 0.842; mean CPM = 1.598; nuclear factor I/A" ID="ID_1057261435" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ERBB3: 1.05-fold Up; FDR = 0.999; PValue = 0.856; mean CPM = 1.467; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)" ID="ID_1839715453" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NEDD4: 1.01-fold Down; FDR = 1; PValue = 0.86; mean CPM = 49.99; neural precursor cell expressed, developmentally down-regulated 4" ID="ID_552893993" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LPL: 1.08-fold Down; FDR = 1; PValue = 0.868; mean CPM = 0.9050; lipoprotein lipase" ID="ID_227697829" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NAPG: 1.01-fold Up; FDR = 1; PValue = 0.878; mean CPM = 30.61; Gamma-soluble NSF attachment protein; Uncharacterized protein" ID="ID_723205577" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PGM1: 1.01-fold Down; FDR = 1; PValue = 0.881; mean CPM = 75.42; phosphoglucomutase 1" ID="ID_1364160341" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000023784: 1.16-fold Down; FDR = 1; PValue = 0.883; mean CPM = 0.8430; Uncharacterized protein" ID="ID_985852596" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000019192: 1.05-fold Up; FDR = 1; PValue = 0.901; mean CPM = 0.9655; Pyruvate kinase" ID="ID_1887081737" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="POLR2C: 1.01-fold Up; FDR = 1; PValue = 0.901; mean CPM = 62.33; polymerase (RNA) II (DNA directed) polypeptide C, 33kDa" ID="ID_988870582" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000025363: 1.02-fold Up; FDR = 1; PValue = 0.907; mean CPM = 0.8201; Uncharacterized protein" ID="ID_467078170" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SSNA1: 1.01-fold Up; FDR = 1; PValue = 0.913; mean CPM = 42.99; Sjogren syndrome nuclear autoantigen 1" ID="ID_1461918338" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHOG: 1.01-fold Up; FDR = 1; PValue = 0.915; mean CPM = 21.03; ras homolog gene family, member G (rho G)" ID="ID_1846864249" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTSC: 1.02-fold Up; FDR = 1; PValue = 0.932; mean CPM = 2.811; cathepsin C" ID="ID_4871114" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CA12: 1.01-fold Up; FDR = 1; PValue = 0.94; mean CPM = 15.70; carbonic anhydrase XII" ID="ID_1911119383" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GALNT1: 1.01-fold Down; FDR = 1; PValue = 0.946; mean CPM = 152.3; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)" ID="ID_598451170" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CARHSP1: No Change; FDR = 1; PValue = 0.968; mean CPM = 87.44; calcium regulated heat stable protein 1, 24kDa" ID="ID_564659750" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000025639: 1.01-fold Down; FDR = 1; PValue = 0.971; mean CPM = 0.9296; Uncharacterized protein" ID="ID_1001027358" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAM1: No Change; FDR = 1; PValue = 0.98; mean CPM = 305.8; translocation associated membrane protein 1" ID="ID_596498530" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACVR1B: No Change; FDR = 1; PValue = 0.999; mean CPM = 11.63; activin A receptor, type IB" ID="ID_1058088418" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="IL-5 signaling pathway (WP127:Rev45368): FDR = 7.82e-09, PValue = 1.14e-09" ID="ID_582534721" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_1277723008" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1199309288" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5A: 2.28-fold Up; FDR = 6.87e-14; PValue = 8.58e-16; mean CPM = 21.55; signal transducer and activator of transcription 5A" ID="ID_286371476" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_213714986" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_862381950" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1714646640" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_436754418" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1319281432" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPT: 2.89-fold Down; FDR = 3.14e-05; PValue = 3.34e-06; mean CPM = 2.105; microtubule-associated protein tau" ID="ID_1355033746" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB2: 1.38-fold Down; FDR = 4.66e-05; PValue = 5.24e-06; mean CPM = 61.90; ribosomal protein S6 kinase, 70kDa, polypeptide 2" ID="ID_1736796478" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_758056335" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA1: 1.25-fold Down; FDR = 0.0241; PValue = 0.00652; mean CPM = 21.28; ribosomal protein S6 kinase, 90kDa, polypeptide 1" ID="ID_40863862" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1608725279" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_1794846913" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KRAS: 1.35-fold Down; FDR = 0.0401; PValue = 0.0119; mean CPM = 13.10; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog" ID="ID_868898330" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_1157422950" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_1102562773" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3A: 1.18-fold Down; FDR = 0.097; PValue = 0.0338; mean CPM = 25.14; Glycogen synthase kinase-3 alpha; Uncharacterized protein" ID="ID_195546788" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_1194266903" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPRED1: 1.15-fold Up; FDR = 0.143; PValue = 0.0543; mean CPM = 41.74; sprouty-related, EVH1 domain containing 1" ID="ID_724271708" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1822528511" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1964004407" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_1497265215" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CG: 1.88-fold Up; FDR = 0.332; PValue = 0.154; mean CPM = 0.9143; phosphoinositide-3-kinase, catalytic, gamma polypeptide" ID="ID_1111352485" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2: 1.48-fold Up; FDR = 0.384; PValue = 0.184; mean CPM = 1.344; Uncharacterized protein" ID="ID_874081336" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_129589344" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_370018847" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOXO3: 1.08-fold Down; FDR = 0.55; PValue = 0.294; mean CPM = 48.45; forkhead box O3" ID="ID_1660388764" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6: 1.08-fold Up; FDR = 0.584; PValue = 0.318; mean CPM = 892.5; ribosomal protein S6" ID="ID_1356211694" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_420530928" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB1: 1.04-fold Up; FDR = 0.88; PValue = 0.6; mean CPM = 30.80; Uncharacterized protein" ID="ID_1975938529" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_601120354" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL5RA: 1.1-fold Up; FDR = 0.958; PValue = 0.791; mean CPM = 0.8108; interleukin 5 receptor, alpha" ID="ID_282119338" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BTK: No Change; FDR = 1; PValue = 0.965; mean CPM = 0.8336; Bruton agammaglobulinemia tyrosine kinase" ID="ID_1236627933" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SYK: 1.11-fold Up; FDR = 1; PValue = 0.977; mean CPM = 0.8420; spleen tyrosine kinase" ID="ID_912191158" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2: 1.03-fold Up; FDR = 1; PValue = 0.998; mean CPM = 0.7974; interleukin 2" ID="ID_71750316" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Epithelium TarBase (WP2002:Rev45243): FDR = 1.03e-08, PValue = 1.56e-09" ID="ID_1634121092" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="ADAR: 2.84-fold Up; FDR = 8.44e-21; PValue = 2.66e-23; mean CPM = 291.8; adenosine deaminase, RNA-specific" ID="ID_218951280" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BACE1: 2.47-fold Down; FDR = 5.34e-16; PValue = 4.61e-18; mean CPM = 93.58; beta-site APP-cleaving enzyme 1" ID="ID_755816374" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SDCBP: 2.11-fold Up; FDR = 2.04e-15; PValue = 1.89e-17; mean CPM = 226.9; Syntenin-1 isoform 1; Uncharacterized protein" ID="ID_535278408" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL3A1: 20.5-fold Down; FDR = 5.71e-15; PValue = 5.82e-17; mean CPM = 5961; collagen, type III, alpha 1" ID="ID_481683311" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL1A1: 21.5-fold Down; FDR = 1.13e-13; PValue = 1.5e-15; mean CPM = 15389; collagen, type I, alpha 1" ID="ID_314999239" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFAIP2: 3.61-fold Up; FDR = 1.42e-13; PValue = 1.95e-15; mean CPM = 54.70; tumor necrosis factor, alpha-induced protein 2" ID="ID_1961844122" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000036781: 2.4-fold Down; FDR = 1.7e-13; PValue = 2.35e-15; mean CPM = 342.5; Uncharacterized protein" ID="ID_250603968" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHOB: 2.87-fold Down; FDR = 2.74e-13; PValue = 3.96e-15; mean CPM = 84.32; ras homolog gene family, member B" ID="ID_1271578615" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MET: 2.57-fold Up; FDR = 3.56e-13; PValue = 5.22e-15; mean CPM = 242.4; Macaca mulatta met proto-oncogene (hepatocyte growth factor receptor) (MET), mRNA." ID="ID_735844967" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF2R: 2.41-fold Down; FDR = 4.2e-13; PValue = 6.32e-15; mean CPM = 245.2; insulin-like growth factor 2 receptor" ID="ID_179506478" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDLIM7: 2.02-fold Down; FDR = 4.87e-13; PValue = 7.39e-15; mean CPM = 284.3; PDZ and LIM domain 7 (enigma)" ID="ID_1944857882" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMC1: 2.28-fold Down; FDR = 6.46e-13; PValue = 1.01e-14; mean CPM = 812.1; laminin, gamma 1 (formerly LAMB2)" ID="ID_571778462" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SNX6: 1.88-fold Up; FDR = 2.14e-12; PValue = 3.75e-14; mean CPM = 91.06; sorting nexin 6" ID="ID_1852945482" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="UNC93B1: 2.26-fold Up; FDR = 3.4e-12; PValue = 6.25e-14; mean CPM = 28.55; unc-93 homolog B1 (C. elegans)" ID="ID_514445128" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATG9A: 1.77-fold Down; FDR = 1.17e-11; PValue = 2.46e-13; mean CPM = 69.44; ATG9 autophagy related 9 homolog A (S. cerevisiae)" ID="ID_251352845" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BRPF3: 2-fold Down; FDR = 4.77e-11; PValue = 1.17e-12; mean CPM = 36.05; bromodomain and PHD finger containing, 3" ID="ID_675951595" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MRC2: 2.12-fold Down; FDR = 1.81e-10; PValue = 5.07e-12; mean CPM = 772.3; mannose receptor, C type 2" ID="ID_1017284128" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AC137834.2: 2.11-fold Down; FDR = 3.29e-10; PValue = 9.87e-12; mean CPM = 1681; Prolow-density lipoprotein receptor-related protein 1 Precursor (LRP-1)(Alpha-2-macroglobulin receptor)(A2MR)(Apolipoprotein E receptor)(APOER)(CD91 antigen) [Contains Low-density lipoprotein receptor-related protein 1 85 kDa subunit(LRP-85);Low-den /.../ipoprotein receptor-related protein 1 515 kDa subunit(LRP-515);Low-density lipoprotein receptor-related protein 1 intracellular domain(LRPICD)]" ID="ID_1168669154" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="P4HA2: 2.27-fold Down; FDR = 3.92e-10; PValue = 1.2e-11; mean CPM = 511.5; prolyl 4-hydroxylase, alpha polypeptide II" ID="ID_1819969557" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPRF: 2.51-fold Down; FDR = 5.51e-10; PValue = 1.77e-11; mean CPM = 184.0; protein tyrosine phosphatase, receptor type, F" ID="ID_548717332" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGFR: 1.84-fold Up; FDR = 6.71e-09; PValue = 2.77e-10; mean CPM = 68.58; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)" ID="ID_1363443894" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1B: 1.64-fold Up; FDR = 1.22e-08; PValue = 5.39e-10; mean CPM = 32.96; Cyclin-dependent kinase inhibitor 1B; Uncharacterized protein" ID="ID_1997412568" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TPM4: 1.8-fold Down; FDR = 1.34e-08; PValue = 5.96e-10; mean CPM = 1400; tropomyosin 4" ID="ID_1894660774" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SCYL1: 1.55-fold Down; FDR = 1.88e-08; PValue = 8.75e-10; mean CPM = 136.7; SCY1-like 1 (S. cerevisiae)" ID="ID_247758921" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDCP1: 2.18-fold Up; FDR = 2.98e-08; PValue = 1.46e-09; mean CPM = 134.3; CUB domain containing protein 1" ID="ID_402727540" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EZH2: 2.05-fold Up; FDR = 4.94e-08; PValue = 2.57e-09; mean CPM = 24.23; enhancer of zeste homolog 2 (Drosophila)" ID="ID_355780671" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RB1: 1.65-fold Up; FDR = 6.01e-08; PValue = 3.2e-09; mean CPM = 59.24; retinoblastoma 1" ID="ID_741611389" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="YIF1B: 1.68-fold Down; FDR = 1.19e-07; PValue = 6.76e-09; mean CPM = 70.16; Yip1 interacting factor homolog B (S. cerevisiae)" ID="ID_1067548827" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IDH1: 1.87-fold Up; FDR = 1.39e-07; PValue = 8.02e-09; mean CPM = 56.62; isocitrate dehydrogenase 1 (NADP+), soluble" ID="ID_97566976" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PGRMC1: 1.49-fold Up; FDR = 2.86e-07; PValue = 1.79e-08; mean CPM = 67.51; progesterone receptor membrane component 1" ID="ID_997169759" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PODXL: 4.78-fold Up; FDR = 5.61e-07; PValue = 3.77e-08; mean CPM = 2.315; podocalyxin-like" ID="ID_940234887" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AARSD1: 1.59-fold Down; FDR = 7.9e-07; PValue = 5.53e-08; mean CPM = 19.40; alanyl-tRNA synthetase domain containing 1" ID="ID_794135297" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACP2: 1.49-fold Up; FDR = 9.22e-07; PValue = 6.59e-08; mean CPM = 58.72; acid phosphatase 2, lysosomal" ID="ID_1630970703" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GAK: 1.46-fold Down; FDR = 9.29e-07; PValue = 6.67e-08; mean CPM = 90.22; cyclin G associated kinase" ID="ID_1250413608" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CORO1C: 1.47-fold Down; FDR = 1.18e-06; PValue = 8.66e-08; mean CPM = 186.3; Coronin" ID="ID_98935806" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000002068: 1.63-fold Down; FDR = 2.68e-06; PValue = 2.15e-07; mean CPM = 20.88" ID="ID_484041772" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BACH1: 1.69-fold Up; FDR = 3.53e-06; PValue = 2.94e-07; mean CPM = 503.5; BTB and CNC homology 1, basic leucine zipper transcription factor 1" ID="ID_1886563207" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARHGDIA: 1.49-fold Down; FDR = 3.61e-06; PValue = 3.01e-07; mean CPM = 257.2; Rho GDP dissociation inhibitor (GDI) alpha" ID="ID_1662811108" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFRD1: 1.57-fold Up; FDR = 5.76e-06; PValue = 5.05e-07; mean CPM = 71.59; interferon-related developmental regulator 1" ID="ID_1520791541" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HES1: 2.4-fold Down; FDR = 5.84e-06; PValue = 5.13e-07; mean CPM = 75.36; hairy and enhancer of split 1, (Drosophila)" ID="ID_375231682" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TUBA1A: 1.66-fold Down; FDR = 7.24e-06; PValue = 6.58e-07; mean CPM = 305.6; tubulin, alpha 1a" ID="ID_1032432137" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMED3: 1.49-fold Down; FDR = 7.47e-06; PValue = 6.8e-07; mean CPM = 282.0; transmembrane emp24 protein transport domain containing 3" ID="ID_480028582" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPIB: 1.45-fold Down; FDR = 8.64e-06; PValue = 8.03e-07; mean CPM = 806.4; peptidylprolyl isomerase B (cyclophilin B)" ID="ID_460112902" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMC2: 2.28-fold Down; FDR = 9.83e-06; PValue = 9.24e-07; mean CPM = 16.99; laminin, gamma 2" ID="ID_1872698417" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PHLDB2: 1.45-fold Down; FDR = 1.07e-05; PValue = 1.01e-06; mean CPM = 341.6; pleckstrin homology-like domain, family B, member 2" ID="ID_1584178344" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GAS2L1: 1.5-fold Down; FDR = 1.44e-05; PValue = 1.41e-06; mean CPM = 29.74; growth arrest-specific 2 like 1" ID="ID_1646596735" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT5A: 1.65-fold Down; FDR = 2.5e-05; PValue = 2.59e-06; mean CPM = 136.4; wingless-type MMTV integration site family, member 5A" ID="ID_1016655407" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYO1E: 1.54-fold Down; FDR = 3.16e-05; PValue = 3.37e-06; mean CPM = 330.9; myosin IE" ID="ID_1211467267" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VTI1B: 1.4-fold Up; FDR = 3.18e-05; PValue = 3.4e-06; mean CPM = 42.89; vesicle transport through interaction with t-SNAREs homolog 1B (yeast)" ID="ID_1256717395" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLK1: 2.25-fold Down; FDR = 3.23e-05; PValue = 3.46e-06; mean CPM = 27.29; polo-like kinase 1 (Drosophila)" ID="ID_1152621395" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNG1: 1.38-fold Up; FDR = 6.77e-05; PValue = 8.01e-06; mean CPM = 149.9; cyclin G1" ID="ID_599046769" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HMOX1: 1.94-fold Up; FDR = 7.83e-05; PValue = 9.42e-06; mean CPM = 15.01; heme oxygenase (decycling) 1" ID="ID_1946376812" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GJA1: 1.71-fold Up; FDR = 0.000117; PValue = 1.47e-05; mean CPM = 2600; gap junction protein, alpha 1, 43kDa" ID="ID_1718546099" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMEM109: 1.4-fold Down; FDR = 0.000118; PValue = 1.49e-05; mean CPM = 78.40; transmembrane protein 109" ID="ID_1668008698" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSRP1: 1.59-fold Down; FDR = 0.000168; PValue = 2.23e-05; mean CPM = 630.6; cysteine and glycine-rich protein 1" ID="ID_881666545" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MRM1: 1.59-fold Up; FDR = 0.000177; PValue = 2.37e-05; mean CPM = 8.176; mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)" ID="ID_1288481279" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARF4: 1.35-fold Down; FDR = 0.000178; PValue = 2.38e-05; mean CPM = 179.9; ADP-ribosylation factor 4" ID="ID_325507846" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTRR: 1.38-fold Up; FDR = 0.000187; PValue = 2.52e-05; mean CPM = 32.85; 5-methyltetrahydrofolate-homocysteine methyltransferase reductase" ID="ID_1774750268" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHD1: 1.35-fold Up; FDR = 0.000225; PValue = 3.11e-05; mean CPM = 82.41; chromodomain helicase DNA binding protein 1" ID="ID_1965712934" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP6V0E1: 1.38-fold Up; FDR = 0.000282; PValue = 4.02e-05; mean CPM = 138.5; ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1" ID="ID_1596843606" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDLIM5: 1.52-fold Down; FDR = 0.000341; PValue = 4.98e-05; mean CPM = 521.2; PDZ and LIM domain 5" ID="ID_1802657093" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC25A1: 1.35-fold Down; FDR = 0.000363; PValue = 5.35e-05; mean CPM = 37.11; solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1" ID="ID_919086075" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HOXD8: 2.21-fold Up; FDR = 0.000453; PValue = 6.86e-05; mean CPM = 2.741; homeobox D8" ID="ID_88960138" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FNDC3A: 1.33-fold Up; FDR = 0.000492; PValue = 7.51e-05; mean CPM = 145.6; fibronectin type III domain containing 3A" ID="ID_7799329" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMC1A: 1.33-fold Down; FDR = 0.000521; PValue = 8.03e-05; mean CPM = 42.68; structural maintenance of chromosomes 1A" ID="ID_1539569790" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NRP1: 1.48-fold Up; FDR = 0.000563; PValue = 8.76e-05; mean CPM = 54.61; neuropilin 1" ID="ID_1331641359" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD3: 1.38-fold Up; FDR = 0.000573; PValue = 8.94e-05; mean CPM = 114.9; SMAD family member 3" ID="ID_215324670" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AMIGO2: 2.39-fold Down; FDR = 0.000639; PValue = 0.000101; mean CPM = 22.90; adhesion molecule with Ig-like domain 2" ID="ID_289145599" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FNDC3B: 1.32-fold Down; FDR = 0.000691; PValue = 0.000111; mean CPM = 260.1; fibronectin type III domain containing 3B" ID="ID_7345910" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYR61: 1.38-fold Down; FDR = 0.000719; PValue = 0.000116; mean CPM = 1035; cysteine-rich, angiogenic inducer, 61" ID="ID_431358961" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCKDHB: 1.49-fold Down; FDR = 0.000761; PValue = 0.000123; mean CPM = 9.393; branched chain keto acid dehydrogenase E1, beta polypeptide" ID="ID_878158158" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033454: 1.33-fold Down; FDR = 0.00107; PValue = 0.000183; mean CPM = 1120; Pyruvate kinase" ID="ID_923285319" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C1QBP: 1.36-fold Up; FDR = 0.00107; PValue = 0.000183; mean CPM = 83.61; complement component 1, q subcomponent binding protein" ID="ID_11129810" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DOCK5: 1.3-fold Down; FDR = 0.00111; PValue = 0.00019; mean CPM = 133.4; dedicator of cytokinesis 5" ID="ID_1158564772" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NT5E: 1.42-fold Up; FDR = 0.00145; PValue = 0.000258; mean CPM = 199.3; 5'-nucleotidase, ecto (CD73)" ID="ID_812691765" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WDFY1: 1.3-fold Up; FDR = 0.00145; PValue = 0.000258; mean CPM = 69.31; WD repeat and FYVE domain containing 1" ID="ID_937435823" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMEM189-UBE2V1: 1.29-fold Down; FDR = 0.00163; PValue = 0.000294; mean CPM = 47.08; TMEM189-UBE2V1 readthrough" ID="ID_220507665" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RRP8: 1.41-fold Down; FDR = 0.00182; PValue = 0.000335; mean CPM = 12.14; ribosomal RNA processing 8, methyltransferase, homolog (yeast)" ID="ID_963197847" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAD23B: 1.34-fold Up; FDR = 0.00235; PValue = 0.000445; mean CPM = 210.1; RAD23 homolog B (S. cerevisiae)" ID="ID_1851897176" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DHX15: 1.28-fold Up; FDR = 0.00298; PValue = 0.000582; mean CPM = 152.3; DEAH (Asp-Glu-Ala-His) box polypeptide 15" ID="ID_1317065220" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRPEL2: 1.39-fold Up; FDR = 0.00298; PValue = 0.000584; mean CPM = 21.71; GrpE-like 2, mitochondrial (E. coli)" ID="ID_458780605" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOTCH1: 1.44-fold Down; FDR = 0.0032; PValue = 0.000634; mean CPM = 32.99; Notch homolog 1, translocation-associated (Drosophila)" ID="ID_1804728066" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTHFD2: 1.37-fold Up; FDR = 0.00326; PValue = 0.000646; mean CPM = 158.6; methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase" ID="ID_281328678" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="UTP15: 1.36-fold Up; FDR = 0.00331; PValue = 0.000658; mean CPM = 16.13; UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)" ID="ID_698056290" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSAT1: 1.79-fold Up; FDR = 0.00355; PValue = 0.000715; mean CPM = 220.2; Uncharacterized protein" ID="ID_1509864319" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRPF40A: 1.27-fold Up; FDR = 0.00357; PValue = 0.00072; mean CPM = 164.5; PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)" ID="ID_1678791460" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB4: 1.66-fold Down; FDR = 0.00369; PValue = 0.000748; mean CPM = 5.291; integrin, beta 4" ID="ID_1278512589" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STX7: 1.29-fold Up; FDR = 0.00375; PValue = 0.000762; mean CPM = 40.57; Syntaxin-7; Uncharacterized protein" ID="ID_999656599" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SYPL1: 1.29-fold Up; FDR = 0.00402; PValue = 0.000826; mean CPM = 28.95; synaptophysin-like 1" ID="ID_1818250437" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000023633: 2.4-fold Up; FDR = 0.00403; PValue = 0.00083; mean CPM = 1.597; Uncharacterized protein" ID="ID_1423095263" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NARS: 1.28-fold Up; FDR = 0.00405; PValue = 0.000834; mean CPM = 348.3; asparaginyl-tRNA synthetase" ID="ID_611342369" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TDG: 1.3-fold Down; FDR = 0.00422; PValue = 0.000874; mean CPM = 24.07; thymine-DNA glycosylase" ID="ID_1467456043" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARID1A: 1.27-fold Down; FDR = 0.00443; PValue = 0.000925; mean CPM = 100.8; AT rich interactive domain 1A (SWI-like)" ID="ID_660083342" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC25A24: 1.27-fold Up; FDR = 0.00467; PValue = 0.000982; mean CPM = 71.95; solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24" ID="ID_1055558095" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SEC62: 1.26-fold Up; FDR = 0.00511; PValue = 0.00109; mean CPM = 81.14; SEC62 homolog (S. cerevisiae)" ID="ID_737905902" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FAR1: 1.28-fold Up; FDR = 0.00521; PValue = 0.00111; mean CPM = 33.54; fatty acyl CoA reductase 1" ID="ID_63525530" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC4: 1.38-fold Down; FDR = 0.00526; PValue = 0.00112; mean CPM = 48.60; histone deacetylase 4" ID="ID_1028975071" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VEZT: 1.25-fold Up; FDR = 0.0069; PValue = 0.00153; mean CPM = 74.30; vezatin, adherens junctions transmembrane protein" ID="ID_782507227" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC1A4: 1.4-fold Down; FDR = 0.00754; PValue = 0.0017; mean CPM = 83.85; solute carrier family 1 (glutamate/neutral amino acid transporter), member 4" ID="ID_415779865" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IQGAP3: 1.55-fold Down; FDR = 0.0122; PValue = 0.00296; mean CPM = 43.66; IQ motif containing GTPase activating protein 3" ID="ID_600981709" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHAF1A: 1.42-fold Down; FDR = 0.0138; PValue = 0.00339; mean CPM = 19.62; Uncharacterized protein" ID="ID_1053732851" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRIP13: 1.56-fold Down; FDR = 0.0144; PValue = 0.00359; mean CPM = 13.12; Uncharacterized protein" ID="ID_1439179410" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HSD17B12: 1.26-fold Up; FDR = 0.0145; PValue = 0.0036; mean CPM = 51.46; hydroxysteroid (17-beta) dehydrogenase 12" ID="ID_1601955930" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RTN4: 1.23-fold Up; FDR = 0.0145; PValue = 0.0036; mean CPM = 165.8; Reticulon" ID="ID_1766850420" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARFIP2: 1.23-fold Down; FDR = 0.0147; PValue = 0.00366; mean CPM = 52.18; ADP-ribosylation factor interacting protein 2" ID="ID_340739334" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CPNE8: 1.43-fold Up; FDR = 0.0153; PValue = 0.00384; mean CPM = 8.182; copine VIII" ID="ID_1362278557" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SNX19: 1.22-fold Down; FDR = 0.0154; PValue = 0.00388; mean CPM = 67.24; sorting nexin 19" ID="ID_837548672" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HBXIP: 1.24-fold Up; FDR = 0.0155; PValue = 0.00392; mean CPM = 74.39; Uncharacterized protein" ID="ID_218868133" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GOLGA7: 1.25-fold Up; FDR = 0.0161; PValue = 0.00408; mean CPM = 28.83; golgin A7" ID="ID_1424103650" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LMNB2: 1.32-fold Down; FDR = 0.0162; PValue = 0.00412; mean CPM = 72.73; lamin B2" ID="ID_1173069875" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADIPOR2: 1.46-fold Down; FDR = 0.0179; PValue = 0.00461; mean CPM = 21.90; adiponectin receptor 2" ID="ID_1388643008" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SYNE1: 1.26-fold Up; FDR = 0.0191; PValue = 0.005; mean CPM = 384.7; spectrin repeat containing, nuclear envelope 1" ID="ID_912941508" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYP1B1: 1.38-fold Down; FDR = 0.0201; PValue = 0.00528; mean CPM = 273.1; cytochrome P450, family 1, subfamily B, polypeptide 1" ID="ID_1014864762" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GALNT7: 1.31-fold Up; FDR = 0.0218; PValue = 0.0058; mean CPM = 12.18; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)" ID="ID_307139077" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FSTL1: 1.23-fold Down; FDR = 0.0219; PValue = 0.00585; mean CPM = 1004; microRNA 198" ID="ID_724841122" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SYNE2: 1.42-fold Up; FDR = 0.0223; PValue = 0.00597; mean CPM = 76.79; spectrin repeat containing, nuclear envelope 2" ID="ID_1339590178" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSDE1: 1.22-fold Up; FDR = 0.0231; PValue = 0.0062; mean CPM = 461.0; Uncharacterized protein" ID="ID_1883910631" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BRI3BP: 1.53-fold Down; FDR = 0.0255; PValue = 0.00698; mean CPM = 5.012; BRI3 binding protein" ID="ID_1121069228" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TXN2: 1.21-fold Down; FDR = 0.026; PValue = 0.00713; mean CPM = 40.77; thioredoxin 2" ID="ID_928230283" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AURKB: 1.68-fold Down; FDR = 0.0261; PValue = 0.00715; mean CPM = 10.71; aurora kinase B" ID="ID_1145589183" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PNP: 1.54-fold Up; FDR = 0.0261; PValue = 0.00717; mean CPM = 3.794; Purine nucleoside phosphorylase" ID="ID_758726909" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDIPT: 1.21-fold Down; FDR = 0.0297; PValue = 0.00831; mean CPM = 71.76; CDP-diacylglycerol--inositol 3-phosphatidyltransferase" ID="ID_1842724930" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KCNJ2: 1.99-fold Up; FDR = 0.0298; PValue = 0.00835; mean CPM = 4.009; potassium inwardly-rectifying channel, subfamily J, member 2" ID="ID_1246223335" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MCL1: 1.2-fold Up; FDR = 0.0335; PValue = 0.00961; mean CPM = 193.8; myeloid cell leukemia sequence 1 (BCL2-related)" ID="ID_807284528" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAND1: 1.2-fold Up; FDR = 0.0393; PValue = 0.0116; mean CPM = 164.5; cullin-associated and neddylation-dissociated 1" ID="ID_1433667466" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NUCB1: 1.21-fold Down; FDR = 0.0393; PValue = 0.0116; mean CPM = 323.6; nucleobindin 1" ID="ID_50152690" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KRAS: 1.35-fold Down; FDR = 0.0401; PValue = 0.0119; mean CPM = 13.10; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog" ID="ID_401183644" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FADS1: 1.2-fold Down; FDR = 0.0424; PValue = 0.0126; mean CPM = 133.1; fatty acid desaturase 1" ID="ID_1873519147" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="E2F1: 1.44-fold Down; FDR = 0.0425; PValue = 0.0127; mean CPM = 8.857; E2F transcription factor 1" ID="ID_1619839828" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNA13: 1.25-fold Up; FDR = 0.0428; PValue = 0.0128; mean CPM = 15.41; guanine nucleotide binding protein (G protein), alpha 13" ID="ID_1574998820" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NXN: 1.19-fold Down; FDR = 0.0457; PValue = 0.0138; mean CPM = 70.27; nucleoredoxin" ID="ID_1198421984" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYP51A1: 1.2-fold Down; FDR = 0.0512; PValue = 0.0158; mean CPM = 34.30; cytochrome P450, family 51, subfamily A, polypeptide 1" ID="ID_1280258762" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTX1: 1.19-fold Down; FDR = 0.0589; PValue = 0.0187; mean CPM = 30.48; metaxin 1" ID="ID_1001310806" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFBR2: 1.19-fold Up; FDR = 0.0643; PValue = 0.0208; mean CPM = 350.8; transforming growth factor, beta receptor II (70/80kDa)" ID="ID_727683895" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MRPS33: 1.21-fold Up; FDR = 0.0695; PValue = 0.0228; mean CPM = 20.91; mitochondrial ribosomal protein S33" ID="ID_871153107" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC25A22: 1.22-fold Up; FDR = 0.0697; PValue = 0.0228; mean CPM = 27.74; solute carrier family 25 (mitochondrial carrier: glutamate), member 22" ID="ID_365086135" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD164: 1.17-fold Up; FDR = 0.0745; PValue = 0.0247; mean CPM = 58.11; CD164 molecule, sialomucin" ID="ID_1633236048" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DNAJB1: 1.18-fold Up; FDR = 0.0756; PValue = 0.0252; mean CPM = 33.66; DnaJ (Hsp40) homolog, subfamily B, member 1" ID="ID_220212694" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EHMT1: 1.17-fold Down; FDR = 0.0774; PValue = 0.0259; mean CPM = 58.20; euchromatic histone-lysine N-methyltransferase 1" ID="ID_526127011" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K8: 1.35-fold Down; FDR = 0.0831; PValue = 0.0281; mean CPM = 8.912; mitogen-activated protein kinase kinase kinase 8" ID="ID_964767330" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SERP1: 1.17-fold Down; FDR = 0.0832; PValue = 0.0282; mean CPM = 113.3; Ribosome-associated membrane protein RAMP4-2; Stress-associated endoplasmic reticulum protein 1; Uncharacterized protein" ID="ID_1235449276" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPIF: 1.22-fold Down; FDR = 0.0887; PValue = 0.0304; mean CPM = 22.64; peptidylprolyl isomerase F" ID="ID_1967338468" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="UBE2S: 1.17-fold Down; FDR = 0.0945; PValue = 0.0328; mean CPM = 65.24; ubiquitin-conjugating enzyme E2S" ID="ID_1268733790" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ANP32B: 1.23-fold Up; FDR = 0.1; PValue = 0.0352; mean CPM = 12.72; acidic (leucine-rich) nuclear phosphoprotein 32 family, member B" ID="ID_1513928115" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLDN1: 1.57-fold Up; FDR = 0.1; PValue = 0.0352; mean CPM = 7.527; claudin 1" ID="ID_1303168410" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PNP: 1.29-fold Up; FDR = 0.101; PValue = 0.0357; mean CPM = 44.02; purine nucleoside phosphorylase" ID="ID_1717265765" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FBXW11: 1.16-fold Up; FDR = 0.106; PValue = 0.0378; mean CPM = 64.90; F-box and WD repeat domain containing 11" ID="ID_1923148941" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND1: 1.17-fold Up; FDR = 0.121; PValue = 0.0443; mean CPM = 867.3; cyclin D1" ID="ID_1379275782" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HOXC8: 1.2-fold Down; FDR = 0.122; PValue = 0.0444; mean CPM = 13.73; homeobox C8" ID="ID_162738406" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAI2: 1.15-fold Down; FDR = 0.134; PValue = 0.0501; mean CPM = 356.3; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2" ID="ID_1419623693" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FAM96A: 1.3-fold Up; FDR = 0.152; PValue = 0.0583; mean CPM = 5.371; family with sequence similarity 96, member A" ID="ID_1526249979" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CEP72: 1.39-fold Down; FDR = 0.163; PValue = 0.0636; mean CPM = 2.653; centrosomal protein 72kDa" ID="ID_1321128134" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYLIP: 1.27-fold Down; FDR = 0.163; PValue = 0.0637; mean CPM = 13.73; myosin regulatory light chain interacting protein" ID="ID_1668459306" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZNF622: 1.14-fold Up; FDR = 0.166; PValue = 0.0651; mean CPM = 40.23; zinc finger protein 622" ID="ID_668379747" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SERPINE2: 1.3-fold Up; FDR = 0.169; PValue = 0.0664; mean CPM = 5738; Glia-derived nexin isoform c; Uncharacterized protein" ID="ID_172998035" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAGT1: 1.14-fold Down; FDR = 0.17; PValue = 0.0674; mean CPM = 86.91; magnesium transporter 1" ID="ID_164872613" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC12A2: 1.16-fold Down; FDR = 0.179; PValue = 0.0714; mean CPM = 21.23; solute carrier family 12 (sodium/potassium/chloride transporters), member 2" ID="ID_1957910060" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTPN: 1.13-fold Up; FDR = 0.185; PValue = 0.0746; mean CPM = 120.1; leucine zipper protein 6" ID="ID_1652589714" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHEB: 1.13-fold Up; FDR = 0.193; PValue = 0.0785; mean CPM = 118.9; Ras homolog enriched in brain" ID="ID_323511399" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PHC2: 1.13-fold Up; FDR = 0.194; PValue = 0.0789; mean CPM = 182.9; polyhomeotic homolog 2 (Drosophila)" ID="ID_1183712117" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WDR82: 1.13-fold Up; FDR = 0.194; PValue = 0.0791; mean CPM = 43.33; WD repeat domain 82" ID="ID_798105548" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHMP2A: 1.13-fold Up; FDR = 0.197; PValue = 0.0805; mean CPM = 122.1; chromatin modifying protein 2A" ID="ID_979985613" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACAA2: 1.13-fold Up; FDR = 0.198; PValue = 0.0811; mean CPM = 42.36; acetyl-CoA acyltransferase 2" ID="ID_477390502" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="POLD2: 1.15-fold Down; FDR = 0.21; PValue = 0.0872; mean CPM = 59.57; polymerase (DNA directed), delta 2, regulatory subunit 50kDa" ID="ID_1642826967" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="YWHAQ: 1.13-fold Up; FDR = 0.216; PValue = 0.0903; mean CPM = 187.3; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide" ID="ID_1793134427" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAI14: 1.13-fold Down; FDR = 0.233; PValue = 0.0989; mean CPM = 323.5; retinoic acid induced 14" ID="ID_1551947940" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAB6A: 1.12-fold Up; FDR = 0.234; PValue = 0.0994; mean CPM = 78.40; RAB6A, member RAS oncogene family" ID="ID_169666908" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SNAP29: 1.13-fold Up; FDR = 0.239; PValue = 0.102; mean CPM = 28.83; synaptosomal-associated protein, 29kDa" ID="ID_1478759502" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAB34: 1.12-fold Down; FDR = 0.24; PValue = 0.103; mean CPM = 96.35; RAB34, member RAS oncogene family" ID="ID_635551302" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RDH10: 1.22-fold Up; FDR = 0.27; PValue = 0.119; mean CPM = 17.06; retinol dehydrogenase 10 (all-trans)" ID="ID_860846516" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LTN1: 1.11-fold Up; FDR = 0.29; PValue = 0.13; mean CPM = 87.31; listerin E3 ubiquitin protein ligase 1" ID="ID_816675116" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DCAF7: 1.12-fold Down; FDR = 0.301; PValue = 0.136; mean CPM = 29.90; DDB1 and CUL4 associated factor 7" ID="ID_1076082020" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GEMIN7: 1.18-fold Down; FDR = 0.301; PValue = 0.136; mean CPM = 8.388; gem (nuclear organelle) associated protein 7" ID="ID_80226460" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK6: 1.18-fold Down; FDR = 0.301; PValue = 0.136; mean CPM = 26.51; cyclin-dependent kinase 6" ID="ID_1596457523" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMED2: 1.11-fold Down; FDR = 0.312; PValue = 0.142; mean CPM = 201.8; transmembrane emp24 domain trafficking protein 2" ID="ID_1363465844" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TH1L: 1.11-fold Down; FDR = 0.315; PValue = 0.144; mean CPM = 56.09; TH1-like (Drosophila)" ID="ID_1885839851" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC4A10: 1.9-fold Down; FDR = 0.326; PValue = 0.15; mean CPM = 0.8928; Sodium-driven chloride bicarbonate exchanger isoform 2; Uncharacterized protein" ID="ID_1362009952" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DMTF1: 1.11-fold Up; FDR = 0.331; PValue = 0.153; mean CPM = 32.97; cyclin D binding myb-like transcription factor 1" ID="ID_866964324" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAPG: 1.11-fold Up; FDR = 0.334; PValue = 0.155; mean CPM = 333.3; capping protein (actin filament), gelsolin-like" ID="ID_1992823636" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF10B: 1.13-fold Down; FDR = 0.343; PValue = 0.16; mean CPM = 40.59; tumor necrosis factor receptor superfamily, member 10b" ID="ID_202678545" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPL: 1.29-fold Up; FDR = 0.353; PValue = 0.166; mean CPM = 11.54; periplakin" ID="ID_588653658" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSNK1D: 1.1-fold Down; FDR = 0.378; PValue = 0.18; mean CPM = 93.44; casein kinase 1, delta" ID="ID_127846477" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COMMD9: 1.11-fold Up; FDR = 0.396; PValue = 0.192; mean CPM = 23.54; COMM domain containing 9" ID="ID_1577336925" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_266236116" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KDELC2: 1.11-fold Up; FDR = 0.461; PValue = 0.232; mean CPM = 32.03; KDEL (Lys-Asp-Glu-Leu) containing 2" ID="ID_546118363" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PURA: 1.1-fold Down; FDR = 0.475; PValue = 0.242; mean CPM = 19.43; purine-rich element binding protein A" ID="ID_1798289524" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CLOCK: 1.09-fold Up; FDR = 0.49; PValue = 0.251; mean CPM = 42.77; clock circadian regulator" ID="ID_578420108" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP1R7: 1.09-fold Down; FDR = 0.491; PValue = 0.253; mean CPM = 35.27; protein phosphatase 1, regulatory subunit 7" ID="ID_748598848" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TYMS: 1.11-fold Up; FDR = 0.494; PValue = 0.254; mean CPM = 71.74; thymidylate synthetase" ID="ID_1263292511" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTBP1: 1.08-fold Down; FDR = 0.5; PValue = 0.258; mean CPM = 205.6; polypyrimidine tract binding protein 1" ID="ID_516736822" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOTCH2: 1.09-fold Down; FDR = 0.514; PValue = 0.268; mean CPM = 795.0; Notch homolog 2 (Drosophila)" ID="ID_939397062" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCI: 1.08-fold Up; FDR = 0.518; PValue = 0.271; mean CPM = 47.99; protein kinase C, iota" ID="ID_662463800" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HNRNPM: 1.08-fold Down; FDR = 0.521; PValue = 0.273; mean CPM = 171.6; heterogeneous nuclear ribonucleoprotein M" ID="ID_1971094107" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLEKHC1: 1.08-fold Up; FDR = 0.529; PValue = 0.278; mean CPM = 251.5; fermitin family homolog 2 (Drosophila)" ID="ID_1464558539" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MBNL1: 1.08-fold Up; FDR = 0.574; PValue = 0.311; mean CPM = 371.7; muscleblind-like (Drosophila)" ID="ID_709361673" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SRSF9: 1.07-fold Down; FDR = 0.595; PValue = 0.326; mean CPM = 49.60; Uncharacterized protein" ID="ID_532244761" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATG3: 1.07-fold Up; FDR = 0.653; PValue = 0.37; mean CPM = 66.70; ATG3 autophagy related 3 homolog (S. cerevisiae)" ID="ID_317475844" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DDX5: 1.07-fold Up; FDR = 0.662; PValue = 0.377; mean CPM = 756.3; DEAD (Asp-Glu-Ala-Asp) box polypeptide 5" ID="ID_1353176572" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRMT1: 1.07-fold Up; FDR = 0.683; PValue = 0.394; mean CPM = 34.90; TRM1 tRNA methyltransferase 1 homolog (S. cerevisiae)" ID="ID_85833365" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATP2A2: 1.06-fold Down; FDR = 0.705; PValue = 0.411; mean CPM = 361.0; ATPase, Ca++ transporting, cardiac muscle, slow twitch 2" ID="ID_147092461" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LY6K: 1.41-fold Up; FDR = 0.737; PValue = 0.438; mean CPM = 0.8830; lymphocyte antigen 6 complex, locus K" ID="ID_1496109149" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP53INP1: 1.12-fold Up; FDR = 0.743; PValue = 0.444; mean CPM = 8.273; tumor protein p53 inducible nuclear protein 1" ID="ID_376737448" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMEM43: 1.05-fold Down; FDR = 0.783; PValue = 0.48; mean CPM = 121.5; transmembrane protein 43" ID="ID_750601210" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SFRS13A: 1.49-fold Down; FDR = 0.79; PValue = 0.486; mean CPM = 0.8044; splicing factor, arginine/serine-rich 13A" ID="ID_1440863046" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMED7-TICAM2: 1.05-fold Down; FDR = 0.796; PValue = 0.493; mean CPM = 150.6; TMED7-TICAM2 readthrough" ID="ID_1293437260" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ABCF2: 1.05-fold Down; FDR = 0.8; PValue = 0.496; mean CPM = 75.45; ATP-binding cassette, sub-family F (GCN20), member 2" ID="ID_139051942" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC38A2: 1.05-fold Up; FDR = 0.808; PValue = 0.504; mean CPM = 193.5; solute carrier family 38, member 2" ID="ID_1401837693" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMED10: 1.05-fold Down; FDR = 0.821; PValue = 0.52; mean CPM = 318.9; transmembrane emp24-like trafficking protein 10 (yeast)" ID="ID_355221898" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP5C: 1.05-fold Up; FDR = 0.826; PValue = 0.526; mean CPM = 49.97; protein phosphatase 5, catalytic subunit" ID="ID_572285379" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CUL4B: 1.04-fold Up; FDR = 0.836; PValue = 0.541; mean CPM = 53.38; cullin 4B" ID="ID_1762108581" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL6: 1.06-fold Down; FDR = 0.837; PValue = 0.542; mean CPM = 64.49; B-cell CLL/lymphoma 6" ID="ID_421902689" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000023221: 1.32-fold Up; FDR = 0.854; PValue = 0.567; mean CPM = 0.7977" ID="ID_1456686189" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NUFIP2: 1.04-fold Down; FDR = 0.854; PValue = 0.567; mean CPM = 77.45; nuclear fragile X mental retardation protein interacting protein 2" ID="ID_1463813676" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TCL1A: 1.28-fold Up; FDR = 0.873; PValue = 0.591; mean CPM = 0.7961; T-cell leukemia/lymphoma 1A" ID="ID_695772748" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RARS: 1.04-fold Up; FDR = 0.888; PValue = 0.61; mean CPM = 124.3; arginyl-tRNA synthetase" ID="ID_1426538736" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LCLAT1: 1.06-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 8.655; lysocardiolipin acyltransferase 1" ID="ID_1641778801" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000024007: 1.24-fold Up; FDR = 0.898; PValue = 0.622; mean CPM = 0.8140; Uncharacterized protein" ID="ID_1058628842" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MPZL1: 1.03-fold Up; FDR = 0.902; PValue = 0.639; mean CPM = 84.36; myelin protein zero-like 1" ID="ID_449241430" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATRX: 1.03-fold Down; FDR = 0.903; PValue = 0.645; mean CPM = 98.18; alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae)" ID="ID_754224806" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PGC: 1.36-fold Down; FDR = 0.906; PValue = 0.668; mean CPM = 0.8398; progastricsin (pepsinogen C)" ID="ID_1338665669" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MRPS24: 1.03-fold Down; FDR = 0.909; PValue = 0.684; mean CPM = 36.51; mitochondrial ribosomal protein S24" ID="ID_708081860" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TERT: 1.35-fold Down; FDR = 0.909; PValue = 0.691; mean CPM = 0.8377; telomerase reverse transcriptase" ID="ID_592295614" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCL: 1.03-fold Up; FDR = 0.909; PValue = 0.691; mean CPM = 392.4; nucleolin" ID="ID_1527388491" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000011953: 1.14-fold Up; FDR = 0.911; PValue = 0.701; mean CPM = 0.7953; Uncharacterized protein" ID="ID_1562112978" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1C: 1.14-fold Up; FDR = 0.932; PValue = 0.743; mean CPM = 1.145; cyclin-dependent kinase inhibitor 1C (p57, Kip2)" ID="ID_549836086" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAT2A: 1.02-fold Up; FDR = 0.935; PValue = 0.747; mean CPM = 130.5; methionine adenosyltransferase II, alpha" ID="ID_1232314692" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB1: 1.02-fold Down; FDR = 0.936; PValue = 0.749; mean CPM = 62.61; transforming growth factor, beta 1" ID="ID_1712125087" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R4: 1.02-fold Down; FDR = 0.943; PValue = 0.763; mean CPM = 93.45; protein phosphatase 2A activator, regulatory subunit 4" ID="ID_846585329" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK5RAP3: 1.02-fold Down; FDR = 0.943; PValue = 0.764; mean CPM = 56.54; Uncharacterized protein" ID="ID_1912305693" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000018123: 1.02-fold Down; FDR = 0.964; PValue = 0.8; mean CPM = 57.60; Uncharacterized protein" ID="ID_1608180891" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000018123: 1.02-fold Down; FDR = 0.964; PValue = 0.8; mean CPM = 57.60; Uncharacterized protein" ID="ID_320285472" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000013347: 1.15-fold Down; FDR = 0.971; PValue = 0.812; mean CPM = 0.8040; Pyruvate kinase" ID="ID_854760140" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPLAD1: 1.02-fold Up; FDR = 0.98; PValue = 0.825; mean CPM = 47.79; protein tyrosine phosphatase-like A domain containing 1" ID="ID_1077697994" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADPGK: 1.02-fold Down; FDR = 0.983; PValue = 0.83; mean CPM = 66.90; ADP-dependent glucokinase" ID="ID_771718887" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PGC: 1.14-fold Down; FDR = 0.985; PValue = 0.834; mean CPM = 0.8351; progastricsin (pepsinogen C)" ID="ID_949957327" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NEDD4: 1.01-fold Down; FDR = 1; PValue = 0.86; mean CPM = 49.99; neural precursor cell expressed, developmentally down-regulated 4" ID="ID_1276329057" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PGM1: 1.01-fold Down; FDR = 1; PValue = 0.881; mean CPM = 75.42; phosphoglucomutase 1" ID="ID_242782829" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000019192: 1.05-fold Up; FDR = 1; PValue = 0.901; mean CPM = 0.9655; Pyruvate kinase" ID="ID_1193773336" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="POLR2C: 1.01-fold Up; FDR = 1; PValue = 0.901; mean CPM = 62.33; polymerase (RNA) II (DNA directed) polypeptide C, 33kDa" ID="ID_1353710820" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000025363: 1.02-fold Up; FDR = 1; PValue = 0.907; mean CPM = 0.8201; Uncharacterized protein" ID="ID_633430456" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MPDU1: 1.01-fold Up; FDR = 1; PValue = 0.919; mean CPM = 43.22; Uncharacterized protein" ID="ID_1174398049" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ANXA2: 1.01-fold Up; FDR = 1; PValue = 0.921; mean CPM = 3870; Annexin" ID="ID_1727307946" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTSC: 1.02-fold Up; FDR = 1; PValue = 0.932; mean CPM = 2.811; cathepsin C" ID="ID_55508864" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CA12: 1.01-fold Up; FDR = 1; PValue = 0.94; mean CPM = 15.70; carbonic anhydrase XII" ID="ID_1956651037" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GALNT1: 1.01-fold Down; FDR = 1; PValue = 0.946; mean CPM = 152.3; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)" ID="ID_638716824" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000025639: 1.01-fold Down; FDR = 1; PValue = 0.971; mean CPM = 0.9296; Uncharacterized protein" ID="ID_511324521" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAM1: No Change; FDR = 1; PValue = 0.98; mean CPM = 305.8; translocation associated membrane protein 1" ID="ID_1827786517" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000028735: No Change; FDR = 1; PValue = 1; mean CPM = 0.7796; Uncharacterized protein" ID="ID_1066754331" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Folate Metabolism (WP176:Rev45271): FDR = 1.69e-08, PValue = 2.64e-09" ID="ID_1155474045" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CSF1: 7.34-fold Up; FDR = 4.6e-20; PValue = 1.69e-22; mean CPM = 149.8; colony stimulating factor 1 (macrophage)" ID="ID_996884759" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ICAM1: 24.6-fold Up; FDR = 2.39e-17; PValue = 1.64e-19; mean CPM = 232.4; intercellular adhesion molecule 1" ID="ID_1559965347" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL2: 24.6-fold Up; FDR = 1.83e-15; PValue = 1.69e-17; mean CPM = 668.2; Macaca mulatta chemokine (C-C motif) ligand 2 (CCL2), mRNA." ID="ID_1909248371" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOD1: 1.67-fold Up; FDR = 3.83e-10; PValue = 1.17e-11; mean CPM = 160.0; superoxide dismutase 1, soluble" ID="ID_9228030" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAT: 1.75-fold Up; FDR = 1.21e-09; PValue = 4.14e-11; mean CPM = 42.72; catalase" ID="ID_191095982" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INSR: 1.93-fold Down; FDR = 1.24e-08; PValue = 5.48e-10; mean CPM = 118.3; insulin receptor" ID="ID_1345538251" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOD2: 4.88-fold Up; FDR = 1.73e-08; PValue = 7.93e-10; mean CPM = 558.4; superoxide dismutase 2, mitochondrial" ID="ID_858623272" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_511750715" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ABCA1: 2.65-fold Up; FDR = 5.3e-07; PValue = 3.52e-08; mean CPM = 203.4; ATP-binding cassette, sub-family A (ABC1), member 1" ID="ID_1806010305" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RFK: 2-fold Up; FDR = 1.24e-05; PValue = 1.19e-06; mean CPM = 7.534; riboflavin kinase" ID="ID_376184979" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTHFS: 1.7-fold Up; FDR = 8.32e-05; PValue = 1.01e-05; mean CPM = 7.979; 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)" ID="ID_1679637175" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_905570505" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTRR: 1.38-fold Up; FDR = 0.000187; PValue = 2.52e-05; mean CPM = 32.85; 5-methyltetrahydrofolate-homocysteine methyltransferase reductase" ID="ID_99420160" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SCARB1: 1.44-fold Down; FDR = 0.000494; PValue = 7.55e-05; mean CPM = 14.81; scavenger receptor class B, member 1" ID="ID_775558069" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SERPINE1: 1.58-fold Down; FDR = 0.00232; PValue = 0.000438; mean CPM = 5294; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1" ID="ID_656697189" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTHFD2: 1.37-fold Up; FDR = 0.00326; PValue = 0.000646; mean CPM = 158.6; methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase" ID="ID_764806562" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOD3: 1.7-fold Down; FDR = 0.00506; PValue = 0.00107; mean CPM = 36.72; superoxide dismutase 3, extracellular" ID="ID_302770340" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FLAD1: 1.27-fold Up; FDR = 0.00617; PValue = 0.00135; mean CPM = 31.00; Uncharacterized protein" ID="ID_1350209965" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTH: 1.72-fold Up; FDR = 0.00927; PValue = 0.00216; mean CPM = 23.63; cystathionase (cystathionine gamma-lyase)" ID="ID_1513943869" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLAT: 1.37-fold Down; FDR = 0.034; PValue = 0.00976; mean CPM = 76.44; plasminogen activator, tissue" ID="ID_1626047004" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1761711847" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SERPINA3: 1.78-fold Down; FDR = 0.0544; PValue = 0.017; mean CPM = 6.499; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3" ID="ID_774027750" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTR: 1.18-fold Down; FDR = 0.0633; PValue = 0.0203; mean CPM = 75.25; 5-methyltetrahydrofolate-homocysteine methyltransferase" ID="ID_1462922617" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APOA1: 2.5-fold Down; FDR = 0.104; PValue = 0.0368; mean CPM = 0.9574; apolipoprotein A-I" ID="ID_174584420" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="F2: 1.67-fold Down; FDR = 0.132; PValue = 0.0494; mean CPM = 1.475; coagulation factor II (thrombin)" ID="ID_1618529493" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GART: 1.13-fold Up; FDR = 0.215; PValue = 0.0896; mean CPM = 54.95; phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase" ID="ID_1071740458" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTHFR: 1.17-fold Down; FDR = 0.235; PValue = 0.1; mean CPM = 12.57; methylenetetrahydrofolate reductase (NAD(P)H)" ID="ID_1513834531" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP53: 1.11-fold Down; FDR = 0.364; PValue = 0.172; mean CPM = 33.25; tumor protein p53" ID="ID_827213977" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOLR1: 1.58-fold Up; FDR = 0.49; PValue = 0.252; mean CPM = 0.9729; folate receptor 1 (adult)" ID="ID_1134760610" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC19A1: 1.13-fold Down; FDR = 0.615; PValue = 0.34; mean CPM = 10.02; solute carrier family 19 (folate transporter), member 1" ID="ID_1312817620" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTHFD1: 1.09-fold Up; FDR = 0.646; PValue = 0.364; mean CPM = 60.07; Uncharacterized protein" ID="ID_1355419356" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_1865651601" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHMT1: 1.18-fold Down; FDR = 0.679; PValue = 0.39; mean CPM = 2.898; serine hydroxymethyltransferase 1 (soluble)" ID="ID_766430257" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APOB: 1.36-fold Down; FDR = 0.723; PValue = 0.426; mean CPM = 0.9779; apolipoprotein B (including Ag(x) antigen)" ID="ID_524295432" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LDLR: 1.07-fold Down; FDR = 0.854; PValue = 0.567; mean CPM = 167.3; low density lipoprotein receptor" ID="ID_993875829" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOLR2: 1.25-fold Down; FDR = 0.88; PValue = 0.599; mean CPM = 0.9554; folate receptor 2 (fetal)" ID="ID_986619163" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HBB: 1.21-fold Up; FDR = 0.883; PValue = 0.603; mean CPM = 0.9754; hemoglobin, beta" ID="ID_1177559942" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_409856463" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_10348160" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAT1A: 1.31-fold Down; FDR = 0.903; PValue = 0.656; mean CPM = 0.8409; methionine adenosyltransferase I, alpha" ID="ID_1562126940" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="F7: 1.07-fold Down; FDR = 0.921; PValue = 0.723; mean CPM = 2.252; coagulation factor VII (serum prothrombin conversion accelerator)" ID="ID_180836268" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HBA1: 1.14-fold Up; FDR = 0.929; PValue = 0.738; mean CPM = 0.8217; hemoglobin, alpha 1" ID="ID_71517282" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL4: 1.27-fold Down; FDR = 0.933; PValue = 0.745; mean CPM = 0.8077; interleukin 4" ID="ID_1402485960" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLG: 1.41-fold Down; FDR = 0.937; PValue = 0.751; mean CPM = 0.8390; plasminogen" ID="ID_1062468482" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HBA2: 1.16-fold Up; FDR = 0.942; PValue = 0.76; mean CPM = 0.8111; hemoglobin, alpha 2" ID="ID_1216910794" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC46A1: 1.06-fold Up; FDR = 0.951; PValue = 0.777; mean CPM = 3.272; solute carrier family 46 (folate transporter), member 1" ID="ID_242738935" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ALB: 1.05-fold Down; FDR = 1; PValue = 0.98; mean CPM = 0.8186; Serum albumin" ID="ID_1305159343" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL2: 1.03-fold Up; FDR = 1; PValue = 0.998; mean CPM = 0.7974; interleukin 2" ID="ID_720193344" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRP: No Change; FDR = 1; PValue = 1; mean CPM = 0.7818; Uncharacterized protein" ID="ID_1142176535" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="TWEAK Signaling Pathway (WP2036:Rev44633): FDR = 2.2e-08, PValue = 3.75e-09" ID="ID_658505570" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="CASP8: 2.73-fold Up; FDR = 6.46e-17; PValue = 4.92e-19; mean CPM = 44.10; caspase 8, apoptosis-related cysteine peptidase" ID="ID_1740753010" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL2: 24.6-fold Up; FDR = 1.83e-15; PValue = 1.69e-17; mean CPM = 668.2; Macaca mulatta chemokine (C-C motif) ligand 2 (CCL2), mRNA." ID="ID_210425903" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIRC2: 1.96-fold Up; FDR = 1.01e-10; PValue = 2.62e-12; mean CPM = 53.58; baculoviral IAP repeat-containing 2" ID="ID_1507152317" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIPK1: 1.75-fold Up; FDR = 1.37e-08; PValue = 6.12e-10; mean CPM = 19.95; receptor (TNFRSF)-interacting serine-threonine kinase 1" ID="ID_1614129887" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1385848987" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL5: 6.74-fold Up; FDR = 2.65e-07; PValue = 1.64e-08; mean CPM = 30.35; chemokine (C-C motif) ligand 5" ID="ID_1465367001" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP3: 1.6-fold Up; FDR = 2.75e-07; PValue = 1.71e-08; mean CPM = 23.53; caspase 3, apoptosis-related cysteine peptidase" ID="ID_113221923" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_582549736" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1569759391" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF1: 2.6-fold Down; FDR = 1.48e-05; PValue = 1.46e-06; mean CPM = 20.19; TNF receptor-associated factor 1" ID="ID_381056575" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_1962408385" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP9: 4.49-fold Down; FDR = 0.00222; PValue = 0.000419; mean CPM = 6.597; matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)" ID="ID_326732448" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_331089819" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF12A: 1.24-fold Down; FDR = 0.0133; PValue = 0.00326; mean CPM = 478.0; tumor necrosis factor receptor superfamily, member 12A" ID="ID_1239492765" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC1: 1.25-fold Up; FDR = 0.0159; PValue = 0.00403; mean CPM = 27.51; histone deacetylase 1" ID="ID_861637791" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1093118490" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_714882578" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_130342649" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTNNB1: 1.2-fold Up; FDR = 0.0498; PValue = 0.0153; mean CPM = 558.3; catenin (cadherin-associated protein), beta 1, 88kDa" ID="ID_1976719418" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELB: 1.22-fold Down; FDR = 0.0606; PValue = 0.0193; mean CPM = 26.64; v-rel reticuloendotheliosis viral oncogene homolog B" ID="ID_1248575687" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF12-TNFSF13: 1.27-fold Up; FDR = 0.0755; PValue = 0.0251; mean CPM = 8.814; TNFSF12-TNFSF13 readthrough" ID="ID_211046023" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FADD: 1.18-fold Down; FDR = 0.0936; PValue = 0.0324; mean CPM = 30.89; Uncharacterized protein" ID="ID_261339260" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_1468891130" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_1340463644" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_509903449" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_892643743" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CASP7: 1.15-fold Up; FDR = 0.218; PValue = 0.0916; mean CPM = 21.49; caspase 7, apoptosis-related cysteine peptidase" ID="ID_171810209" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1284687127" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1851800969" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF3: 1.07-fold Up; FDR = 0.611; PValue = 0.338; mean CPM = 34.56; TNF receptor-associated factor 3" ID="ID_830101962" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033547: 1.37-fold Up; FDR = 0.769; PValue = 0.467; mean CPM = 0.8946; Uncharacterized protein" ID="ID_511670236" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF25: 1.2-fold Up; FDR = 0.772; PValue = 0.471; mean CPM = 1.687; tumor necrosis factor receptor superfamily, member 25" ID="ID_45415537" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CD163: 1.24-fold Down; FDR = 0.785; PValue = 0.482; mean CPM = 1.694; Uncharacterized protein" ID="ID_1189516442" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1777094652" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_313239391" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_1871486076" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_1939609790" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIB: No Change; FDR = 1; PValue = 0.954; mean CPM = 29.12; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta" ID="ID_1362926852" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Glycolysis and Gluconeogenesis (WP534:Rev45332): FDR = 2.2e-08, PValue = 3.75e-09" ID="ID_703767836" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="PC: 2.94-fold Down; FDR = 2.05e-12; PValue = 3.55e-14; mean CPM = 48.99; pyruvate carboxylase" ID="ID_1232633248" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC2A5: 2.6-fold Up; FDR = 9.78e-07; PValue = 7.06e-08; mean CPM = 317.8; solute carrier family 2 (facilitated glucose/fructose transporter), member 5" ID="ID_87754822" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ALDOC: 2-fold Down; FDR = 4.17e-06; PValue = 3.52e-07; mean CPM = 13.04; aldolase C, fructose-bisphosphate" ID="ID_1442509942" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LDHB: 1.58-fold Up; FDR = 9.22e-06; PValue = 8.6e-07; mean CPM = 42.97; lactate dehydrogenase B" ID="ID_285177039" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PFKM: 1.39-fold Up; FDR = 2.67e-05; PValue = 2.79e-06; mean CPM = 72.22; phosphofructokinase, muscle" ID="ID_938917277" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MDH2: 1.39-fold Down; FDR = 3.22e-05; PValue = 3.44e-06; mean CPM = 112.2; malate dehydrogenase 2, NAD (mitochondrial)" ID="ID_1647908651" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000032006: 1.51-fold Up; FDR = 0.000767; PValue = 0.000125; mean CPM = 66.79; L-lactate dehydrogenase" ID="ID_1732397931" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000033454: 1.33-fold Down; FDR = 0.00107; PValue = 0.000183; mean CPM = 1120; Pyruvate kinase" ID="ID_1109602185" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDHB: 1.28-fold Down; FDR = 0.00241; PValue = 0.000459; mean CPM = 56.68; pyruvate dehydrogenase (lipoamide) beta" ID="ID_1882972006" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC2A3: 1.33-fold Up; FDR = 0.00247; PValue = 0.00047; mean CPM = 714.2; solute carrier family 2 (facilitated glucose transporter), member 3" ID="ID_1194401451" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PGK1: 1.27-fold Up; FDR = 0.0115; PValue = 0.00275; mean CPM = 662.7; phosphoglycerate kinase 1" ID="ID_274173312" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HK2: 1.22-fold Up; FDR = 0.0214; PValue = 0.0057; mean CPM = 215.1; hexokinase 2" ID="ID_1913135861" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PKLR: 1.57-fold Up; FDR = 0.0362; PValue = 0.0105; mean CPM = 2.948; pyruvate kinase, liver and RBC" ID="ID_1341419671" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENO1: 1.22-fold Down; FDR = 0.0484; PValue = 0.0148; mean CPM = 1537; enolase 1, (alpha)" ID="ID_311322623" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GOT2: 1.18-fold Down; FDR = 0.0553; PValue = 0.0173; mean CPM = 50.10; glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)" ID="ID_1782752805" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDHA1: 1.17-fold Down; FDR = 0.0855; PValue = 0.0291; mean CPM = 57.75; pyruvate dehydrogenase (lipoamide) alpha 1" ID="ID_2245932" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DLD: 1.16-fold Up; FDR = 0.12; PValue = 0.0435; mean CPM = 57.77; dihydrolipoamide dehydrogenase" ID="ID_668114634" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FBP1: 2.44-fold Down; FDR = 0.142; PValue = 0.0537; mean CPM = 0.8759; fructose-1,6-bisphosphatase 1" ID="ID_360785705" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FBP2: 2.24-fold Down; FDR = 0.18; PValue = 0.0722; mean CPM = 0.8952; fructose-1,6-bisphosphatase 2" ID="ID_1363382376" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PFKP: 1.12-fold Up; FDR = 0.268; PValue = 0.117; mean CPM = 517.4; phosphofructokinase, platelet" ID="ID_634075307" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENO2: 1.2-fold Down; FDR = 0.289; PValue = 0.129; mean CPM = 27.10; enolase 2 (gamma, neuronal)" ID="ID_1617464798" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PGAM1: 1.25-fold Down; FDR = 0.321; PValue = 0.148; mean CPM = 3.933; Phosphoglycerate mutase 1; Uncharacterized protein" ID="ID_1356208764" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000037417: 1.37-fold Up; FDR = 0.341; PValue = 0.159; mean CPM = 1.887; Enolase" ID="ID_881815785" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GOT1: 1.11-fold Up; FDR = 0.36; PValue = 0.17; mean CPM = 38.06; glutamic-oxaloacetic transaminase 1, soluble" ID="ID_1883486446" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENO3: 1.13-fold Down; FDR = 0.367; PValue = 0.174; mean CPM = 18.18; enolase 3 (beta, muscle)" ID="ID_1010413422" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDHX: 1.11-fold Down; FDR = 0.373; PValue = 0.177; mean CPM = 27.58; pyruvate dehydrogenase complex, component X" ID="ID_662667432" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PFKL: 1.09-fold Down; FDR = 0.48; PValue = 0.245; mean CPM = 237.6; phosphofructokinase, liver" ID="ID_1747728623" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HK3: 1.35-fold Down; FDR = 0.553; PValue = 0.296; mean CPM = 1.330; hexokinase 3 (white cell)" ID="ID_101267410" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TPI1: 1.07-fold Down; FDR = 0.681; PValue = 0.391; mean CPM = 521.3; triosephosphate isomerase 1" ID="ID_1885617508" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GAPDHS: 1.1-fold Up; FDR = 0.688; PValue = 0.398; mean CPM = 6.772; glyceraldehyde-3-phosphate dehydrogenase, spermatogenic" ID="ID_340112306" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LDHC: 1.34-fold Up; FDR = 0.698; PValue = 0.406; mean CPM = 1.061; lactate dehydrogenase C" ID="ID_209176606" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC2A1: 1.06-fold Down; FDR = 0.782; PValue = 0.479; mean CPM = 105.3; solute carrier family 2 (facilitated glucose transporter), member 1" ID="ID_1092492610" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC2A2: 1.33-fold Down; FDR = 0.801; PValue = 0.498; mean CPM = 0.8809; solute carrier family 2 (facilitated glucose transporter), member 2" ID="ID_1323381263" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PGAM1: 1.26-fold Down; FDR = 0.854; PValue = 0.566; mean CPM = 0.8794; phosphoglycerate mutase 1 (brain)" ID="ID_625214570" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DLAT: 1.03-fold Up; FDR = 0.903; PValue = 0.659; mean CPM = 48.33; dihydrolipoamide S-acetyltransferase" ID="ID_1242790551" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GPI: 1.03-fold Up; FDR = 0.904; PValue = 0.662; mean CPM = 547.3; Glucose-6-phosphate isomerase" ID="ID_1656765433" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="G6PC: 1.22-fold Down; FDR = 0.929; PValue = 0.737; mean CPM = 0.8105; glucose-6-phosphatase, catalytic subunit" ID="ID_1388711259" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TPI1: 1.02-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 133.1; triosephosphate isomerase 1" ID="ID_784222022" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000013347: 1.15-fold Down; FDR = 0.971; PValue = 0.812; mean CPM = 0.8040; Pyruvate kinase" ID="ID_205585883" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GCK: 1.05-fold Up; FDR = 0.98; PValue = 0.824; mean CPM = 1.691; glucokinase (hexokinase 4)" ID="ID_1139134034" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LDHA: 1.02-fold Down; FDR = 0.984; PValue = 0.832; mean CPM = 721.4; lactate dehydrogenase A" ID="ID_1052096744" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GAPDH: 1.01-fold Up; FDR = 1; PValue = 0.881; mean CPM = 4027; glyceraldehyde-3-phosphate dehydrogenase" ID="ID_1108593976" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ALDOA: 1.01-fold Down; FDR = 1; PValue = 0.888; mean CPM = 2126; aldolase A, fructose-bisphosphate" ID="ID_781795182" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ALDOB: 1.05-fold Up; FDR = 1; PValue = 0.892; mean CPM = 0.8566; aldolase B, fructose-bisphosphate" ID="ID_334467944" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000019192: 1.05-fold Up; FDR = 1; PValue = 0.901; mean CPM = 0.9655; Pyruvate kinase" ID="ID_490745800" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000036539: 1.04-fold Down; FDR = 1; PValue = 0.924; mean CPM = 1.052; Uncharacterized protein" ID="ID_1312144464" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PCK1: 1.05-fold Down; FDR = 1; PValue = 0.961; mean CPM = 0.8008; phosphoenolpyruvate carboxykinase 1 (soluble)" ID="ID_1664725089" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDHA2: 1.08-fold Down; FDR = 1; PValue = 0.965; mean CPM = 0.7976; pyruvate dehydrogenase (lipoamide) alpha 2" ID="ID_5545388" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PGK2: No Change; FDR = 1; PValue = 1; mean CPM = 0.7869; phosphoglycerate kinase 2" ID="ID_1240612015" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Endochondral Ossification (WP474:Rev45241): FDR = 2.2e-08, PValue = 3.78e-09" ID="ID_24824682" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1331249283" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHST11: 1.89-fold Down; FDR = 5.08e-11; PValue = 1.26e-12; mean CPM = 25.95; carbohydrate (chondroitin 4) sulfotransferase 11" ID="ID_1446522286" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLAU: 3.37-fold Down; FDR = 1.56e-10; PValue = 4.33e-12; mean CPM = 18.78; plasminogen activator, urokinase" ID="ID_1055727094" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MGP: 11.1-fold Down; FDR = 1.95e-10; PValue = 5.56e-12; mean CPM = 46.22; matrix Gla protein" ID="ID_866301751" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SERPINH1: 2.33-fold Down; FDR = 3.72e-10; PValue = 1.13e-11; mean CPM = 1580; serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)" ID="ID_1514549130" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACAN: 8.6-fold Down; FDR = 9.08e-09; PValue = 3.88e-10; mean CPM = 593.8; aggrecan" ID="ID_539830204" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF2: 2.42-fold Up; FDR = 9.98e-09; PValue = 4.31e-10; mean CPM = 134.8; fibroblast growth factor 2 (basic)" ID="ID_296202665" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOX9: 3.15-fold Down; FDR = 1.96e-06; PValue = 1.53e-07; mean CPM = 6.885; SRY (sex determining region Y)-box 9" ID="ID_54691680" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGFR3: 3.85-fold Down; FDR = 2.66e-06; PValue = 2.13e-07; mean CPM = 2.800; fibroblast growth factor receptor 3" ID="ID_1159324913" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_1564288551" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1: 5.76-fold Down; FDR = 6.73e-06; PValue = 6.04e-07; mean CPM = 1.536; insulin-like growth factor 1 (somatomedin C)" ID="ID_113692210" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1R: 1.51-fold Down; FDR = 1.02e-05; PValue = 9.61e-07; mean CPM = 213.2; insulin-like growth factor 1 receptor" ID="ID_284058056" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFT88: 1.43-fold Up; FDR = 7.29e-05; PValue = 8.71e-06; mean CPM = 25.37; intraflagellar transport 88 homolog (Chlamydomonas)" ID="ID_1134141784" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPP1: 2.25-fold Down; FDR = 7.74e-05; PValue = 9.29e-06; mean CPM = 35.33; secreted phosphoprotein 1" ID="ID_385244864" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACA: 1.36-fold Down; FDR = 0.000167; PValue = 2.22e-05; mean CPM = 37.75; protein kinase, cAMP-dependent, catalytic, alpha" ID="ID_900022694" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VEGFA: 1.47-fold Up; FDR = 0.000317; PValue = 4.59e-05; mean CPM = 463.7; vascular endothelial growth factor A" ID="ID_1963542557" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALM3: 1.41-fold Down; FDR = 0.000714; PValue = 0.000115; mean CPM = 94.24; calmodulin 3 (phosphorylase kinase, delta)" ID="ID_1439625503" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADAMTS1: 1.65-fold Down; FDR = 0.000821; PValue = 0.000134; mean CPM = 712.2; ADAM metallopeptidase with thrombospondin type 1 motif, 1" ID="ID_414719122" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MMP9: 4.49-fold Down; FDR = 0.00222; PValue = 0.000419; mean CPM = 6.597; matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)" ID="ID_65591855" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FRZB: 2.1-fold Up; FDR = 0.00475; PValue = 0.001; mean CPM = 4.661; frizzled-related protein" ID="ID_1624606673" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC4: 1.38-fold Down; FDR = 0.00526; PValue = 0.00112; mean CPM = 48.60; histone deacetylase 4" ID="ID_868779730" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HMGCS1: 1.31-fold Down; FDR = 0.00578; PValue = 0.00125; mean CPM = 19.39; 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)" ID="ID_1803762121" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL10A1: 2.53-fold Down; FDR = 0.0119; PValue = 0.00286; mean CPM = 1.365; collagen, type X, alpha 1" ID="ID_867378012" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1181814934" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLAT: 1.37-fold Down; FDR = 0.034; PValue = 0.00976; mean CPM = 76.44; plasminogen activator, tissue" ID="ID_114595459" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL2A1: 2.38-fold Down; FDR = 0.0368; PValue = 0.0107; mean CPM = 1.117; Uncharacterized protein" ID="ID_925689613" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSH-3: 2.19-fold Up; FDR = 0.0771; PValue = 0.0258; mean CPM = 1.335; Macaca mulatta chorionic somatommamotropin hormone 3 (CSH-3), mRNA." ID="ID_1887640111" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTH1R: 2-fold Down; FDR = 0.0838; PValue = 0.0284; mean CPM = 1.299; parathyroid hormone 1 receptor" ID="ID_384951213" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BMP6: 1.74-fold Down; FDR = 0.0895; PValue = 0.0307; mean CPM = 2.386; bone morphogenetic protein 6" ID="ID_343519606" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALM1: 1.18-fold Down; FDR = 0.104; PValue = 0.0368; mean CPM = 292.9; calmodulin 1 (phosphorylase kinase, delta)" ID="ID_587044897" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGFR1: 1.15-fold Down; FDR = 0.139; PValue = 0.0525; mean CPM = 89.41; fibroblast growth factor receptor 1" ID="ID_1235950661" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTSL2: 2.28-fold Down; FDR = 0.143; PValue = 0.0541; mean CPM = 0.9217; cathepsin L2" ID="ID_371643421" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GLI3: 1.21-fold Down; FDR = 0.211; PValue = 0.0875; mean CPM = 42.23; GLI family zinc finger 3" ID="ID_1350899549" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTCH1: 1.14-fold Down; FDR = 0.32; PValue = 0.147; mean CPM = 13.18; patched homolog 1 (Drosophila)" ID="ID_1717432826" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RUNX2: 1.24-fold Down; FDR = 0.328; PValue = 0.152; mean CPM = 8.937; runt-related transcription factor 2" ID="ID_1504527997" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALM1: 1.11-fold Up; FDR = 0.343; PValue = 0.16; mean CPM = 412.7; Calmodulin; Uncharacterized protein" ID="ID_1081412478" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENPP1: 1.2-fold Down; FDR = 0.346; PValue = 0.162; mean CPM = 147.6; ectonucleotide pyrophosphatase/phosphodiesterase 1" ID="ID_712962067" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADAMTS5: 1.26-fold Down; FDR = 0.354; PValue = 0.166; mean CPM = 36.26; ADAM metallopeptidase with thrombospondin type 1 motif, 5" ID="ID_847704047" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MEF2C: 1.24-fold Down; FDR = 0.357; PValue = 0.168; mean CPM = 6.816; myocyte enhancer factor 2C" ID="ID_1117417026" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GHR: 1.23-fold Up; FDR = 0.369; PValue = 0.175; mean CPM = 6.312; growth hormone receptor" ID="ID_1563661650" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAB39: 1.11-fold Up; FDR = 0.371; PValue = 0.176; mean CPM = 33.59; calcium binding protein 39" ID="ID_737656024" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF2: 1.42-fold Up; FDR = 0.383; PValue = 0.183; mean CPM = 31.20; insulin-like growth factor 2 (somatomedin A)" ID="ID_1768506244" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="THRA: 1.12-fold Down; FDR = 0.401; PValue = 0.195; mean CPM = 14.87; thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)" ID="ID_792424428" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RUNX3: 1.41-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 1.666; runt-related transcription factor 3" ID="ID_911334908" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOX5: 1.4-fold Up; FDR = 0.536; PValue = 0.284; mean CPM = 1.420; SRY (sex determining region Y)-box 5" ID="ID_1406013342" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF18: 1.55-fold Down; FDR = 0.548; PValue = 0.293; mean CPM = 0.9359; fibroblast growth factor 18" ID="ID_620625076" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ALPL: 1.27-fold Up; FDR = 0.625; PValue = 0.348; mean CPM = 2.290; alkaline phosphatase, liver/bone/kidney" ID="ID_1290862565" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DDR2: 1.07-fold Up; FDR = 0.633; PValue = 0.355; mean CPM = 236.3; discoidin domain receptor tyrosine kinase 2" ID="ID_1913964455" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADAMTS4: 1.18-fold Down; FDR = 0.655; PValue = 0.372; mean CPM = 6.172; ADAM metallopeptidase with thrombospondin type 1 motif, 4" ID="ID_70302222" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOX6: 1.32-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 1.240; SRY (sex determining region Y)-box 6" ID="ID_379612729" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IHH: 1.37-fold Down; FDR = 0.68; PValue = 0.391; mean CPM = 1.025; Indian hedgehog homolog (Drosophila)" ID="ID_1729909824" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CST5: 1.61-fold Down; FDR = 0.807; PValue = 0.504; mean CPM = 0.8117; cystatin D" ID="ID_443210008" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SLC38A2: 1.05-fold Up; FDR = 0.808; PValue = 0.504; mean CPM = 193.5; solute carrier family 38, member 2" ID="ID_353088661" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BMPR1A: 1.04-fold Up; FDR = 0.903; PValue = 0.641; mean CPM = 36.13; bone morphogenetic protein receptor, type IA" ID="ID_356962103" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB2: 1.05-fold Down; FDR = 0.903; PValue = 0.655; mean CPM = 110.8; transforming growth factor, beta 2" ID="ID_498462104" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NKX3-2: 1.35-fold Up; FDR = 0.925; PValue = 0.731; mean CPM = 0.8228; NK3 homeobox 2" ID="ID_300561548" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1C: 1.14-fold Up; FDR = 0.932; PValue = 0.743; mean CPM = 1.145; cyclin-dependent kinase inhibitor 1C (p57, Kip2)" ID="ID_1913238711" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB1: 1.02-fold Down; FDR = 0.936; PValue = 0.749; mean CPM = 62.61; transforming growth factor, beta 1" ID="ID_1003722897" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016883: 1.11-fold Down; FDR = 0.97; PValue = 0.811; mean CPM = 0.8838; Uncharacterized protein" ID="ID_1913110608" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTHLH: 1.13-fold Down; FDR = 1; PValue = 0.935; mean CPM = 0.8502; Uncharacterized protein" ID="ID_7076899" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SCIN: 1.04-fold Up; FDR = 1; PValue = 0.951; mean CPM = 0.8773; scinderin" ID="ID_463310805" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BMP7: 1.01-fold Up; FDR = 1; PValue = 0.994; mean CPM = 0.8010; bone morphogenetic protein 7" ID="ID_1248489172" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTH: No Change; FDR = 1; PValue = 1; mean CPM = 0.7843; parathyroid hormone" ID="ID_1711667608" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Vitamin B12 Metabolism (WP1533:Rev45013): FDR = 4.25e-08, PValue = 7.52e-09" ID="ID_363154687" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="ICAM1: 24.6-fold Up; FDR = 2.39e-17; PValue = 1.64e-19; mean CPM = 232.4; intercellular adhesion molecule 1" ID="ID_1961555675" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL2: 24.6-fold Up; FDR = 1.83e-15; PValue = 1.69e-17; mean CPM = 668.2; Macaca mulatta chemokine (C-C motif) ligand 2 (CCL2), mRNA." ID="ID_538441561" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOD1: 1.67-fold Up; FDR = 3.83e-10; PValue = 1.17e-11; mean CPM = 160.0; superoxide dismutase 1, soluble" ID="ID_636544871" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INSR: 1.93-fold Down; FDR = 1.24e-08; PValue = 5.48e-10; mean CPM = 118.3; insulin receptor" ID="ID_702865277" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOD2: 4.88-fold Up; FDR = 1.73e-08; PValue = 7.93e-10; mean CPM = 558.4; superoxide dismutase 2, mitochondrial" ID="ID_136267251" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1297621860" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL5: 6.74-fold Up; FDR = 2.65e-07; PValue = 1.64e-08; mean CPM = 30.35; chemokine (C-C motif) ligand 5" ID="ID_1693758018" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ABCA1: 2.65-fold Up; FDR = 5.3e-07; PValue = 3.52e-08; mean CPM = 203.4; ATP-binding cassette, sub-family A (ABC1), member 1" ID="ID_392824030" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_1594497647" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTRR: 1.38-fold Up; FDR = 0.000187; PValue = 2.52e-05; mean CPM = 32.85; 5-methyltetrahydrofolate-homocysteine methyltransferase reductase" ID="ID_1836753474" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SCARB1: 1.44-fold Down; FDR = 0.000494; PValue = 7.55e-05; mean CPM = 14.81; scavenger receptor class B, member 1" ID="ID_101831322" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SERPINE1: 1.58-fold Down; FDR = 0.00232; PValue = 0.000438; mean CPM = 5294; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1" ID="ID_969243296" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOD3: 1.7-fold Down; FDR = 0.00506; PValue = 0.00107; mean CPM = 36.72; superoxide dismutase 3, extracellular" ID="ID_684390579" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTH: 1.72-fold Up; FDR = 0.00927; PValue = 0.00216; mean CPM = 23.63; cystathionase (cystathionine gamma-lyase)" ID="ID_341492211" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TCN2: 1.6-fold Down; FDR = 0.0118; PValue = 0.00282; mean CPM = 5.020; transcobalamin II" ID="ID_412172739" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APOE: 1.75-fold Down; FDR = 0.0148; PValue = 0.00369; mean CPM = 24.21; apolipoprotein E" ID="ID_1103814888" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MUT: 1.23-fold Up; FDR = 0.0232; PValue = 0.00626; mean CPM = 31.80; methylmalonyl CoA mutase" ID="ID_1965237952" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLAT: 1.37-fold Down; FDR = 0.034; PValue = 0.00976; mean CPM = 76.44; plasminogen activator, tissue" ID="ID_1036613602" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1524662412" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SERPINA3: 1.78-fold Down; FDR = 0.0544; PValue = 0.017; mean CPM = 6.499; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3" ID="ID_1025893914" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTR: 1.18-fold Down; FDR = 0.0633; PValue = 0.0203; mean CPM = 75.25; 5-methyltetrahydrofolate-homocysteine methyltransferase" ID="ID_985032029" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APOA1: 2.5-fold Down; FDR = 0.104; PValue = 0.0368; mean CPM = 0.9574; apolipoprotein A-I" ID="ID_1009775567" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="F2: 1.67-fold Down; FDR = 0.132; PValue = 0.0494; mean CPM = 1.475; coagulation factor II (thrombin)" ID="ID_1243164031" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GIF: 2.15-fold Down; FDR = 0.186; PValue = 0.0747; mean CPM = 0.8950; gastric intrinsic factor (vitamin B synthesis)" ID="ID_1300584843" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LRP2: 1.78-fold Down; FDR = 0.225; PValue = 0.0948; mean CPM = 1.099; low density lipoprotein receptor-related protein 2" ID="ID_524669412" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTHFR: 1.17-fold Down; FDR = 0.235; PValue = 0.1; mean CPM = 12.57; methylenetetrahydrofolate reductase (NAD(P)H)" ID="ID_850738893" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MCEE: 1.1-fold Up; FDR = 0.587; PValue = 0.321; mean CPM = 11.90; methylmalonyl CoA epimerase" ID="ID_1119454390" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_1124038478" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APOB: 1.36-fold Down; FDR = 0.723; PValue = 0.426; mean CPM = 0.9779; apolipoprotein B (including Ag(x) antigen)" ID="ID_1377491622" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TCN1: 1.84-fold Down; FDR = 0.76; PValue = 0.459; mean CPM = 0.8497; transcobalamin I (vitamin B12 binding protein, R binder family)" ID="ID_1779927143" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LDLR: 1.07-fold Down; FDR = 0.854; PValue = 0.567; mean CPM = 167.3; low density lipoprotein receptor" ID="ID_1942930264" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HBB: 1.21-fold Up; FDR = 0.883; PValue = 0.603; mean CPM = 0.9754; hemoglobin, beta" ID="ID_989191979" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_101502972" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_647095262" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAT1A: 1.31-fold Down; FDR = 0.903; PValue = 0.656; mean CPM = 0.8409; methionine adenosyltransferase I, alpha" ID="ID_245893295" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="F7: 1.07-fold Down; FDR = 0.921; PValue = 0.723; mean CPM = 2.252; coagulation factor VII (serum prothrombin conversion accelerator)" ID="ID_896845998" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HBA1: 1.14-fold Up; FDR = 0.929; PValue = 0.738; mean CPM = 0.8217; hemoglobin, alpha 1" ID="ID_812268523" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLG: 1.41-fold Down; FDR = 0.937; PValue = 0.751; mean CPM = 0.8390; plasminogen" ID="ID_1387353998" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HBA2: 1.16-fold Up; FDR = 0.942; PValue = 0.76; mean CPM = 0.8111; hemoglobin, alpha 2" ID="ID_431484647" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ALB: 1.05-fold Down; FDR = 1; PValue = 0.98; mean CPM = 0.8186; Serum albumin" ID="ID_636495451" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000036214: 1.04-fold Down; FDR = 1; PValue = 0.988; mean CPM = 0.8094; Uncharacterized protein" ID="ID_1698155123" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRP: No Change; FDR = 1; PValue = 1; mean CPM = 0.7818; Uncharacterized protein" ID="ID_453525614" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Selenium Pathway (WP15:Rev45021): FDR = 5.71e-08, PValue = 1.04e-08" ID="ID_1597289830" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="ICAM1: 24.6-fold Up; FDR = 2.39e-17; PValue = 1.64e-19; mean CPM = 232.4; intercellular adhesion molecule 1" ID="ID_175802879" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCL2: 24.6-fold Up; FDR = 1.83e-15; PValue = 1.69e-17; mean CPM = 668.2; Macaca mulatta chemokine (C-C motif) ligand 2 (CCL2), mRNA." ID="ID_575220852" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOD1: 1.67-fold Up; FDR = 3.83e-10; PValue = 1.17e-11; mean CPM = 160.0; superoxide dismutase 1, soluble" ID="ID_1599941558" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAT: 1.75-fold Up; FDR = 1.21e-09; PValue = 4.14e-11; mean CPM = 42.72; catalase" ID="ID_1391097538" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INSR: 1.93-fold Down; FDR = 1.24e-08; PValue = 5.48e-10; mean CPM = 118.3; insulin receptor" ID="ID_826063905" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOD2: 4.88-fold Up; FDR = 1.73e-08; PValue = 7.93e-10; mean CPM = 558.4; superoxide dismutase 2, mitochondrial" ID="ID_1314193214" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_1331849371" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ABCA1: 2.65-fold Up; FDR = 5.3e-07; PValue = 3.52e-08; mean CPM = 203.4; ATP-binding cassette, sub-family A (ABC1), member 1" ID="ID_1412465763" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RFK: 2-fold Up; FDR = 1.24e-05; PValue = 1.19e-06; mean CPM = 7.534; riboflavin kinase" ID="ID_1009916056" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_760591414" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRDX3: 1.35-fold Up; FDR = 0.000161; PValue = 2.12e-05; mean CPM = 79.39; peroxiredoxin 3" ID="ID_1890230711" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KYNU: 1.76-fold Up; FDR = 0.000177; PValue = 2.37e-05; mean CPM = 157.2; kynureninase (L-kynurenine hydrolase)" ID="ID_236773942" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTGS2: 2.02-fold Up; FDR = 0.000254; PValue = 3.59e-05; mean CPM = 314.5; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)" ID="ID_1590134811" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SCARB1: 1.44-fold Down; FDR = 0.000494; PValue = 7.55e-05; mean CPM = 14.81; scavenger receptor class B, member 1" ID="ID_339444099" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRDX2: 1.31-fold Down; FDR = 0.00103; PValue = 0.000174; mean CPM = 49.31; Peroxiredoxin-2; Peroxiredoxin-2 isoform a; Uncharacterized protein" ID="ID_739277067" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SERPINE1: 1.58-fold Down; FDR = 0.00232; PValue = 0.000438; mean CPM = 5294; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1" ID="ID_1382473634" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOD3: 1.7-fold Down; FDR = 0.00506; PValue = 0.00107; mean CPM = 36.72; superoxide dismutase 3, extracellular" ID="ID_216998788" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FLAD1: 1.27-fold Up; FDR = 0.00617; PValue = 0.00135; mean CPM = 31.00; Uncharacterized protein" ID="ID_1876918148" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTH: 1.72-fold Up; FDR = 0.00927; PValue = 0.00216; mean CPM = 23.63; cystathionase (cystathionine gamma-lyase)" ID="ID_876692493" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRDX2: 1.32-fold Down; FDR = 0.0159; PValue = 0.00402; mean CPM = 11.74; peroxiredoxin 2" ID="ID_1867887427" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSR: 1.26-fold Up; FDR = 0.0263; PValue = 0.00721; mean CPM = 28.15; glutathione reductase" ID="ID_689392084" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ALOX5AP: 2.75-fold Down; FDR = 0.0327; PValue = 0.00932; mean CPM = 1.072; arachidonate 5-lipoxygenase-activating protein" ID="ID_41688965" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLAT: 1.37-fold Down; FDR = 0.034; PValue = 0.00976; mean CPM = 76.44; plasminogen activator, tissue" ID="ID_1292845531" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_599752792" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SERPINA3: 1.78-fold Down; FDR = 0.0544; PValue = 0.017; mean CPM = 6.499; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3" ID="ID_326428013" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTR: 1.18-fold Down; FDR = 0.0633; PValue = 0.0203; mean CPM = 75.25; 5-methyltetrahydrofolate-homocysteine methyltransferase" ID="ID_822410619" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRDX1: 1.17-fold Up; FDR = 0.104; PValue = 0.0366; mean CPM = 384.6; peroxiredoxin 1" ID="ID_1544434887" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APOA1: 2.5-fold Down; FDR = 0.104; PValue = 0.0368; mean CPM = 0.9574; apolipoprotein A-I" ID="ID_1180929829" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="F2: 1.67-fold Down; FDR = 0.132; PValue = 0.0494; mean CPM = 1.475; coagulation factor II (thrombin)" ID="ID_1108839291" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TXN: 1.14-fold Up; FDR = 0.184; PValue = 0.0741; mean CPM = 93.12; thioredoxin" ID="ID_799812742" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TXN: 1.15-fold Up; FDR = 0.211; PValue = 0.0875; mean CPM = 147.9; Macaca mulatta thioredoxin (TXN), mRNA." ID="ID_1676263850" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRDX5: 1.13-fold Up; FDR = 0.22; PValue = 0.0922; mean CPM = 162.7; peroxiredoxin 5" ID="ID_1448329800" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTHFR: 1.17-fold Down; FDR = 0.235; PValue = 0.1; mean CPM = 12.57; methylenetetrahydrofolate reductase (NAD(P)H)" ID="ID_1087380445" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PNPO: 1.15-fold Down; FDR = 0.245; PValue = 0.105; mean CPM = 16.00; pyridoxamine 5'-phosphate oxidase" ID="ID_41453974" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTGS1: 1.18-fold Down; FDR = 0.368; PValue = 0.175; mean CPM = 116.4; Uncharacterized protein" ID="ID_118568365" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ALOX5: 1.56-fold Up; FDR = 0.49; PValue = 0.251; mean CPM = 0.9979; arachidonate 5-lipoxygenase" ID="ID_1371756073" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="XDH: 1.62-fold Up; FDR = 0.495; PValue = 0.255; mean CPM = 0.9209; xanthine dehydrogenase" ID="ID_162234601" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KMO: 1.52-fold Up; FDR = 0.643; PValue = 0.362; mean CPM = 0.8796; Kynurenine 3-monooxygenase" ID="ID_209210257" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_617491054" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APOB: 1.36-fold Down; FDR = 0.723; PValue = 0.426; mean CPM = 0.9779; apolipoprotein B (including Ag(x) antigen)" ID="ID_1783987506" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRDX4: 1.06-fold Down; FDR = 0.726; PValue = 0.428; mean CPM = 70.33; peroxiredoxin 4" ID="ID_354091667" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LDLR: 1.07-fold Down; FDR = 0.854; PValue = 0.567; mean CPM = 167.3; low density lipoprotein receptor" ID="ID_1895481937" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HBB: 1.21-fold Up; FDR = 0.883; PValue = 0.603; mean CPM = 0.9754; hemoglobin, beta" ID="ID_1253947857" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNF: 1.28-fold Down; FDR = 0.888; PValue = 0.611; mean CPM = 0.8049; Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form]" ID="ID_12649494" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IFNG: 1.24-fold Up; FDR = 0.899; PValue = 0.63; mean CPM = 0.7892; interferon, gamma" ID="ID_1000343267" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ALOX15B: 1.32-fold Up; FDR = 0.906; PValue = 0.67; mean CPM = 0.8315; arachidonate 15-lipoxygenase, type B" ID="ID_330375458" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="F7: 1.07-fold Down; FDR = 0.921; PValue = 0.723; mean CPM = 2.252; coagulation factor VII (serum prothrombin conversion accelerator)" ID="ID_1194360868" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HBA1: 1.14-fold Up; FDR = 0.929; PValue = 0.738; mean CPM = 0.8217; hemoglobin, alpha 1" ID="ID_899238351" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLG: 1.41-fold Down; FDR = 0.937; PValue = 0.751; mean CPM = 0.8390; plasminogen" ID="ID_868575883" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HBA2: 1.16-fold Up; FDR = 0.942; PValue = 0.76; mean CPM = 0.8111; hemoglobin, alpha 2" ID="ID_1594356109" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ALB: 1.05-fold Down; FDR = 1; PValue = 0.98; mean CPM = 0.8186; Serum albumin" ID="ID_595566936" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRP: No Change; FDR = 1; PValue = 1; mean CPM = 0.7818; Uncharacterized protein" ID="ID_1685378611" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="RANKL/RANK Signaling Pathway (WP2018:Rev45591): FDR = 5.79e-08, PValue = 1.08e-08" ID="ID_1579031295" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="ICAM1: 24.6-fold Up; FDR = 2.39e-17; PValue = 1.64e-19; mean CPM = 232.4; intercellular adhesion molecule 1" ID="ID_1490808577" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_899078829" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1548589903" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_56031541" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1900194818" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_367379708" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF1: 2.6-fold Down; FDR = 1.48e-05; PValue = 1.46e-06; mean CPM = 20.19; TNF receptor-associated factor 1" ID="ID_553691885" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_75623931" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP2: 1.45-fold Up; FDR = 0.000179; PValue = 2.4e-05; mean CPM = 65.31; TGF-beta activated kinase 1/MAP3K7 binding protein 2" ID="ID_1438849153" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTSK: 1.62-fold Down; FDR = 0.00104; PValue = 0.000176; mean CPM = 20.16; cathepsin K" ID="ID_1186378144" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTOR: 1.3-fold Down; FDR = 0.00117; PValue = 0.000201; mean CPM = 107.5; mechanistic target of rapamycin (serine/threonine kinase)" ID="ID_1232896565" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GAB2: 1.33-fold Down; FDR = 0.00208; PValue = 0.000387; mean CPM = 22.59; GRB2-associated binding protein 2" ID="ID_1108847092" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG1: 1.31-fold Down; FDR = 0.00352; PValue = 0.000707; mean CPM = 53.66; phospholipase C, gamma 1" ID="ID_637983558" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKBIA: 1.42-fold Up; FDR = 0.00531; PValue = 0.00113; mean CPM = 32.72; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" ID="ID_1260792834" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1019030896" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1313549104" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_560631946" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VCAM1: 1.53-fold Up; FDR = 0.0353; PValue = 0.0102; mean CPM = 110.0; vascular cell adhesion molecule 1" ID="ID_1885129152" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFSF11: 1.8-fold Up; FDR = 0.039; PValue = 0.0115; mean CPM = 2.535; tumor necrosis factor (ligand) superfamily, member 11" ID="ID_589800935" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_1336001127" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELB: 1.22-fold Down; FDR = 0.0606; PValue = 0.0193; mean CPM = 26.64; v-rel reticuloendotheliosis viral oncogene homolog B" ID="ID_1407328161" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_1809683322" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF11B: 1.31-fold Down; FDR = 0.121; PValue = 0.0439; mean CPM = 722.1; Uncharacterized protein" ID="ID_105507818" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_1391718866" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1166506452" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SQSTM1: 1.19-fold Down; FDR = 0.289; PValue = 0.129; mean CPM = 270.1; sequestosome 1" ID="ID_1616244792" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7IP1: 1.12-fold Down; FDR = 0.351; PValue = 0.165; mean CPM = 17.96; TGF-beta activated kinase 1/MAP3K7 binding protein 1" ID="ID_479952621" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2: 1.1-fold Up; FDR = 0.394; PValue = 0.191; mean CPM = 102.5; PTK2 protein tyrosine kinase 2" ID="ID_866590631" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_100480077" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_335584635" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFATC1: 1.11-fold Down; FDR = 0.457; PValue = 0.23; mean CPM = 19.06; Uncharacterized protein" ID="ID_833746380" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FHL2: 1.09-fold Up; FDR = 0.483; PValue = 0.247; mean CPM = 400.9; Uncharacterized protein" ID="ID_1404417583" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDC42: 1.07-fold Down; FDR = 0.608; PValue = 0.335; mean CPM = 91.67; cell division cycle 42" ID="ID_251387359" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TRAF3: 1.07-fold Up; FDR = 0.611; PValue = 0.338; mean CPM = 34.56; TNF receptor-associated factor 3" ID="ID_1872206127" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNFRSF11A: 1.4-fold Down; FDR = 0.676; PValue = 0.388; mean CPM = 0.9723; tumor necrosis factor receptor superfamily, member 11a, NFKB activator" ID="ID_1922755461" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CALCR: 1.77-fold Down; FDR = 0.725; PValue = 0.427; mean CPM = 0.8076; Uncharacterized protein" ID="ID_406166454" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CBL: 1.05-fold Down; FDR = 0.824; PValue = 0.524; mean CPM = 51.06; Cas-Br-M (murine) ecotropic retroviral transforming sequence" ID="ID_629909609" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_1007749869" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACP5: 1.16-fold Up; FDR = 0.924; PValue = 0.73; mean CPM = 0.9503; acid phosphatase 5, tartrate resistant" ID="ID_1577931692" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPI1: 1.12-fold Down; FDR = 0.935; PValue = 0.747; mean CPM = 1.030; spleen focus forming virus (SFFV) proviral integration oncogene spi1" ID="ID_1019429491" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_1323621945" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_1365555662" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SYK: 1.11-fold Up; FDR = 1; PValue = 0.977; mean CPM = 0.8420; spleen tyrosine kinase" ID="ID_1839764410" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="TSH signaling pathway (WP2032:Rev44635): FDR = 7.88e-08, PValue = 1.52e-08" ID="ID_69094961" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_1603097166" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1880492806" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_986183647" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND3: 2.27-fold Down; FDR = 8.38e-11; PValue = 2.15e-12; mean CPM = 86.90; cyclin D3" ID="ID_1222774152" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1B: 1.64-fold Up; FDR = 1.22e-08; PValue = 5.39e-10; mean CPM = 32.96; Cyclin-dependent kinase inhibitor 1B; Uncharacterized protein" ID="ID_1401967081" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RB1: 1.65-fold Up; FDR = 6.01e-08; PValue = 3.2e-09; mean CPM = 59.24; retinoblastoma 1" ID="ID_225239140" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RALGDS: 2.6-fold Up; FDR = 2.12e-07; PValue = 1.28e-08; mean CPM = 47.88; ral guanine nucleotide dissociation stimulator" ID="ID_1556436844" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1B: 1.55-fold Up; FDR = 2.39e-07; PValue = 1.46e-08; mean CPM = 135.3; Ras-related protein Rap-1b; Ras-related protein Rap-1b isoform 1; Uncharacterized protein" ID="ID_1170110906" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_16014710" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCB1: 1.71-fold Up; FDR = 1.31e-06; PValue = 9.73e-08; mean CPM = 34.36; phospholipase C, beta 1 (phosphoinositide-specific)" ID="ID_1077237888" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3CA: 1.47-fold Up; FDR = 1.39e-06; PValue = 1.03e-07; mean CPM = 55.32; phosphoinositide-3-kinase, catalytic, alpha polypeptide" ID="ID_1570457140" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K3: 1.45-fold Down; FDR = 7.01e-06; PValue = 6.34e-07; mean CPM = 180.1; mitogen-activated protein kinase kinase 3" ID="ID_494176197" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IGF1R: 1.51-fold Down; FDR = 1.02e-05; PValue = 9.61e-07; mean CPM = 213.2; insulin-like growth factor 1 receptor" ID="ID_1176997682" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1158295091" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAI1: 1.47-fold Up; FDR = 5.94e-05; PValue = 6.9e-06; mean CPM = 97.19; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1" ID="ID_460705663" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SCRIB: 1.37-fold Down; FDR = 0.000163; PValue = 2.15e-05; mean CPM = 68.59; scribbled homolog (Drosophila)" ID="ID_1840475483" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNA12: 1.32-fold Down; FDR = 0.000955; PValue = 0.00016; mean CPM = 33.75; Uncharacterized protein" ID="ID_1795218231" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTOR: 1.3-fold Down; FDR = 0.00117; PValue = 0.000201; mean CPM = 107.5; mechanistic target of rapamycin (serine/threonine kinase)" ID="ID_1436172605" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAS1: 1.31-fold Down; FDR = 0.00158; PValue = 0.000283; mean CPM = 564.9; Uncharacterized protein" ID="ID_1471214860" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1B: 1.43-fold Up; FDR = 0.00346; PValue = 0.000693; mean CPM = 12.81; RAP1B, member of RAS oncogene family" ID="ID_1187983107" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYL12B: 1.28-fold Up; FDR = 0.00408; PValue = 0.00084; mean CPM = 372.0; myosin, light chain 12B, regulatory" ID="ID_852242743" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAI3: 1.26-fold Up; FDR = 0.00487; PValue = 0.00103; mean CPM = 113.8; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3" ID="ID_1217624634" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK2: 1.23-fold Down; FDR = 0.0194; PValue = 0.00507; mean CPM = 36.76; cyclin-dependent kinase 2" ID="ID_756747470" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_2657545" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA1: 1.25-fold Down; FDR = 0.0241; PValue = 0.00652; mean CPM = 21.28; ribosomal protein S6 kinase, 90kDa, polypeptide 1" ID="ID_1049790533" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TTF1: 1.26-fold Up; FDR = 0.0246; PValue = 0.00667; mean CPM = 19.17; transcription termination factor, RNA polymerase I" ID="ID_1923521091" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1768332744" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_705499693" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB1: 1.21-fold Up; FDR = 0.0313; PValue = 0.00884; mean CPM = 36.07; cAMP responsive element binding protein 1" ID="ID_193519445" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDPK1: 1.24-fold Down; FDR = 0.0361; PValue = 0.0105; mean CPM = 17.53; 3-phosphoinositide dependent protein kinase-1" ID="ID_68415627" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="E2F1: 1.44-fold Down; FDR = 0.0425; PValue = 0.0127; mean CPM = 8.857; E2F transcription factor 1" ID="ID_1745884670" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNA13: 1.25-fold Up; FDR = 0.0428; PValue = 0.0128; mean CPM = 15.41; guanine nucleotide binding protein (G protein), alpha 13" ID="ID_495279373" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_206555722" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_515760877" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1A: 1.17-fold Up; FDR = 0.0888; PValue = 0.0304; mean CPM = 37.16; RAP1A, member of RAS oncogene family" ID="ID_622617203" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_1857817319" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNG2: 1.64-fold Up; FDR = 0.117; PValue = 0.0421; mean CPM = 2.320; guanine nucleotide binding protein (G protein), gamma 2" ID="ID_1085255493" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KCNIP3: 1.82-fold Down; FDR = 0.133; PValue = 0.0498; mean CPM = 1.262; Kv channel interacting protein 3, calsenilin" ID="ID_1936130777" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAI2: 1.15-fold Down; FDR = 0.134; PValue = 0.0501; mean CPM = 356.3; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2" ID="ID_570137489" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_1487385133" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLD1: 1.24-fold Down; FDR = 0.162; PValue = 0.0634; mean CPM = 15.80; phospholipase D1, phosphatidylcholine-specific" ID="ID_499432199" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BRAF: 1.14-fold Down; FDR = 0.228; PValue = 0.0964; mean CPM = 24.98; v-raf murine sarcoma viral oncogene homolog B1" ID="ID_1847355963" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNE1: 1.2-fold Up; FDR = 0.278; PValue = 0.123; mean CPM = 6.609; cyclin E1" ID="ID_1348555121" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1753084236" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RBL2: 1.09-fold Up; FDR = 0.445; PValue = 0.222; mean CPM = 47.90; retinoblastoma-like 2 (p130)" ID="ID_1410448642" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_469575701" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNB1: 1.08-fold Down; FDR = 0.565; PValue = 0.305; mean CPM = 299.4; guanine nucleotide binding protein (G protein), beta polypeptide 1" ID="ID_974186729" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6: 1.08-fold Up; FDR = 0.584; PValue = 0.318; mean CPM = 892.5; ribosomal protein S6" ID="ID_835764126" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APEX1: 1.04-fold Up; FDR = 0.858; PValue = 0.571; mean CPM = 95.24; APEX nuclease (multifunctional DNA repair enzyme) 1" ID="ID_1625504029" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY2: 1.18-fold Down; FDR = 0.864; PValue = 0.58; mean CPM = 1.755; adenylate cyclase 2 (brain)" ID="ID_936241327" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB1: 1.04-fold Up; FDR = 0.88; PValue = 0.6; mean CPM = 30.80; Uncharacterized protein" ID="ID_1861297370" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAQ: 1.05-fold Down; FDR = 0.889; PValue = 0.611; mean CPM = 9.623; Guanine nucleotide-binding protein G(Q) subunit alpha; Uncharacterized protein" ID="ID_1987075560" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDK4: 1.04-fold Up; FDR = 0.899; PValue = 0.626; mean CPM = 65.45; cyclin-dependent kinase 4" ID="ID_1909042923" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TSHB: 1.13-fold Down; FDR = 0.911; PValue = 0.702; mean CPM = 0.7879; thyroid stimulating hormone, beta" ID="ID_318945814" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_1761905917" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TSHR: 1.44-fold Down; FDR = 0.963; PValue = 0.799; mean CPM = 0.8693; thyroid stimulating hormone receptor" ID="ID_1887503656" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TTF2: 1.02-fold Down; FDR = 1; PValue = 0.863; mean CPM = 16.60; transcription termination factor, RNA polymerase II" ID="ID_559648950" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAO1: 1.1-fold Down; FDR = 1; PValue = 0.866; mean CPM = 0.8448; guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O" ID="ID_643255423" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY3: 1.01-fold Up; FDR = 1; PValue = 0.871; mean CPM = 34.92; adenylate cyclase 3" ID="ID_92460378" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAX8: 1.06-fold Down; FDR = 1; PValue = 0.878; mean CPM = 0.8841; paired box 8" ID="ID_1627031707" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CGA: 1.01-fold Down; FDR = 1; PValue = 0.952; mean CPM = 0.8464; Glycoprotein hormones alpha chain" ID="ID_1763848017" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GNAQ: No Change; FDR = 1; PValue = 0.975; mean CPM = 15.20; guanine nucleotide binding protein (G protein), q polypeptide" ID="ID_1897175295" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Integrin-mediated cell adhesion (WP185:Rev44862): FDR = 1.1e-07, PValue = 2.17e-08" ID="ID_1570737778" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="ITGA5: 3.79-fold Down; FDR = 1.33e-14; PValue = 1.48e-16; mean CPM = 1237; integrin, alpha 5 (fibronectin receptor, alpha polypeptide)" ID="ID_1981424300" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VCL: 2.48-fold Down; FDR = 5.94e-13; PValue = 9.16e-15; mean CPM = 1013; vinculin" ID="ID_1890457305" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAV: 2.64-fold Down; FDR = 6.04e-11; PValue = 1.51e-12; mean CPM = 337.3; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)" ID="ID_1432734449" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNS1: 2.51-fold Down; FDR = 1.03e-10; PValue = 2.68e-12; mean CPM = 434.5; tensin 1" ID="ID_1834961205" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SORBS1: 2.91-fold Down; FDR = 1.08e-10; PValue = 2.84e-12; mean CPM = 81.82; sorbin and SH3 domain containing 1" ID="ID_1987274813" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB8: 3.97-fold Up; FDR = 6.37e-10; PValue = 2.06e-11; mean CPM = 11.37; integrin, beta 8" ID="ID_245238168" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA2: 2.84-fold Up; FDR = 7.38e-10; PValue = 2.42e-11; mean CPM = 176.3; integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)" ID="ID_1664701683" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB3: 5.02-fold Down; FDR = 1.72e-09; PValue = 6.17e-11; mean CPM = 43.21; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)" ID="ID_1186188274" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_1015499051" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB5: 1.61-fold Down; FDR = 8.23e-09; PValue = 3.47e-10; mean CPM = 471.0; integrin, beta 5" ID="ID_1195406076" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA10: 4.95-fold Down; FDR = 1.77e-08; PValue = 8.13e-10; mean CPM = 5.184; integrin, alpha 10" ID="ID_1898278606" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA8: 4.04-fold Down; FDR = 5.89e-08; PValue = 3.12e-09; mean CPM = 145.8; integrin, alpha 8" ID="ID_18345949" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ILK: 1.53-fold Down; FDR = 5.97e-08; PValue = 3.17e-09; mean CPM = 256.9; integrin-linked kinase" ID="ID_369248042" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1B: 1.55-fold Up; FDR = 2.39e-07; PValue = 1.46e-08; mean CPM = 135.3; Ras-related protein Rap-1b; Ras-related protein Rap-1b isoform 1; Uncharacterized protein" ID="ID_1242767991" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_689181964" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARHGEF7: 1.72-fold Down; FDR = 6.46e-07; PValue = 4.4e-08; mean CPM = 53.66; Rho guanine nucleotide exchange factor (GEF) 7" ID="ID_517799293" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT2: 1.46-fold Down; FDR = 1.51e-06; PValue = 1.13e-07; mean CPM = 65.98; v-akt murine thymoma viral oncogene homolog 2" ID="ID_1207440070" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC3: 1.68-fold Down; FDR = 2.72e-06; PValue = 2.19e-07; mean CPM = 13.98; ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)" ID="ID_399634768" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K3: 1.45-fold Down; FDR = 7.01e-06; PValue = 6.34e-07; mean CPM = 180.1; mitogen-activated protein kinase kinase 3" ID="ID_1354528519" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1867799630" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAPNS1: 1.4-fold Down; FDR = 6.09e-05; PValue = 7.11e-06; mean CPM = 239.1; calpain, small subunit 1" ID="ID_1729174276" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K5: 1.55-fold Up; FDR = 7.6e-05; PValue = 9.12e-06; mean CPM = 16.82; mitogen-activated protein kinase kinase 5" ID="ID_54341200" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCAR1: 1.36-fold Up; FDR = 0.000193; PValue = 2.61e-05; mean CPM = 210.4; breast cancer anti-estrogen resistance 1" ID="ID_1890776520" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="C17orf57: 5.51-fold Down; FDR = 0.000238; PValue = 3.33e-05; mean CPM = 1.571; EF-hand domain-containing protein C17orf57" ID="ID_1947699551" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAPN5: 1.67-fold Down; FDR = 0.00033; PValue = 4.79e-05; mean CPM = 5.965; calpain 5" ID="ID_1561998224" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA3: 1.34-fold Down; FDR = 0.000518; PValue = 7.96e-05; mean CPM = 126.8; integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)" ID="ID_688083313" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZYX: 1.29-fold Down; FDR = 0.00237; PValue = 0.00045; mean CPM = 287.5; Uncharacterized protein" ID="ID_1884171451" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK3: 3.55-fold Up; FDR = 0.00273; PValue = 0.000527; mean CPM = 1.136; p21 protein (Cdc42/Rac)-activated kinase 3" ID="ID_292878604" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1B: 1.43-fold Up; FDR = 0.00346; PValue = 0.000693; mean CPM = 12.81; RAP1B, member of RAS oncogene family" ID="ID_1628650183" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB4: 1.66-fold Down; FDR = 0.00369; PValue = 0.000748; mean CPM = 5.291; integrin, beta 4" ID="ID_1500828670" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV3: 1.82-fold Down; FDR = 0.00463; PValue = 0.000973; mean CPM = 7.044; vav 3 guanine nucleotide exchange factor" ID="ID_1843872314" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAV1: 1.33-fold Down; FDR = 0.00575; PValue = 0.00125; mean CPM = 228.7; caveolin-1" ID="ID_1482236071" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VASP: 1.26-fold Down; FDR = 0.00581; PValue = 0.00126; mean CPM = 250.9; vasodilator-stimulated phosphoprotein" ID="ID_1845965211" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_291952132" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAPN7: 1.26-fold Up; FDR = 0.00973; PValue = 0.00227; mean CPM = 38.08; calpain 7" ID="ID_1835258577" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TLN1: 1.26-fold Down; FDR = 0.0101; PValue = 0.00238; mean CPM = 1820; talin 1" ID="ID_117892300" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FYN: 1.22-fold Up; FDR = 0.0156; PValue = 0.00393; mean CPM = 92.94; FYN oncogene related to SRC, FGR, YES" ID="ID_1462439727" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB2: 1.55-fold Down; FDR = 0.0187; PValue = 0.00485; mean CPM = 34.87; Integrin beta" ID="ID_406890791" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA2B: 1.71-fold Down; FDR = 0.0187; PValue = 0.00486; mean CPM = 2.655; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)" ID="ID_1837788917" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_2197302" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_955473965" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC2: 2.96-fold Up; FDR = 0.0309; PValue = 0.00872; mean CPM = 0.9737; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)" ID="ID_816798186" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDPK1: 1.24-fold Down; FDR = 0.0361; PValue = 0.0105; mean CPM = 17.53; 3-phosphoinositide dependent protein kinase-1" ID="ID_442703918" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK6: 3.06-fold Down; FDR = 0.04; PValue = 0.0118; mean CPM = 0.9224; p21 protein (Cdc42/Rac)-activated kinase 6" ID="ID_1725256753" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_1346327662" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK4: 1.21-fold Down; FDR = 0.0756; PValue = 0.0252; mean CPM = 16.78; p21 protein (Cdc42/Rac)-activated kinase 4" ID="ID_633011854" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB1: 1.23-fold Up; FDR = 0.0759; PValue = 0.0253; mean CPM = 2700; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)" ID="ID_632124453" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1A: 1.17-fold Up; FDR = 0.0888; PValue = 0.0304; mean CPM = 37.16; RAP1A, member of RAS oncogene family" ID="ID_478376038" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK2: 1.15-fold Up; FDR = 0.134; PValue = 0.0502; mean CPM = 89.49; p21 protein (Cdc42/Rac)-activated kinase 2" ID="ID_236880640" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAPN11: 1.86-fold Down; FDR = 0.159; PValue = 0.0616; mean CPM = 1.173; calpain 11" ID="ID_51299216" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ROCK2: 1.14-fold Up; FDR = 0.166; PValue = 0.065; mean CPM = 247.7; Rho-associated, coiled-coil containing protein kinase 2" ID="ID_1795835968" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1534493389" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_1802144430" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BRAF: 1.14-fold Down; FDR = 0.228; PValue = 0.0964; mean CPM = 24.98; v-raf murine sarcoma viral oncogene homolog B1" ID="ID_1005733999" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAV2: 1.14-fold Down; FDR = 0.24; PValue = 0.103; mean CPM = 25.69; caveolin 2" ID="ID_1819329333" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT3: 1.13-fold Down; FDR = 0.281; PValue = 0.125; mean CPM = 38.03; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)" ID="ID_146050968" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2: 1.1-fold Up; FDR = 0.394; PValue = 0.191; mean CPM = 102.5; PTK2 protein tyrosine kinase 2" ID="ID_860167691" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHO: 1.78-fold Down; FDR = 0.395; PValue = 0.191; mean CPM = 0.8794; rhodopsin" ID="ID_990968537" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK6: 1.34-fold Up; FDR = 0.407; PValue = 0.198; mean CPM = 2.043; mitogen-activated protein kinase 6" ID="ID_1690438291" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK12: 1.19-fold Down; FDR = 0.422; PValue = 0.208; mean CPM = 6.569; mitogen-activated protein kinase 12" ID="ID_976442897" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYLK2: 1.56-fold Down; FDR = 0.541; PValue = 0.288; mean CPM = 0.9259; myosin light chain kinase 2" ID="ID_1413035545" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA1: 1.1-fold Down; FDR = 0.57; PValue = 0.308; mean CPM = 422.3; integrin, alpha 1" ID="ID_808440377" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC3: 1.37-fold Down; FDR = 0.584; PValue = 0.318; mean CPM = 1.193; SHC-transforming protein 3; Uncharacterized protein" ID="ID_431502695" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA9: 1.3-fold Down; FDR = 0.595; PValue = 0.326; mean CPM = 1.685; integrin, alpha 9" ID="ID_809830453" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDC42: 1.07-fold Down; FDR = 0.608; PValue = 0.335; mean CPM = 91.67; cell division cycle 42" ID="ID_1609178851" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSK: 1.06-fold Down; FDR = 0.673; PValue = 0.386; mean CPM = 45.36; c-src tyrosine kinase" ID="ID_1093815216" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGA4: 1.16-fold Down; FDR = 0.722; PValue = 0.425; mean CPM = 5.425; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)" ID="ID_1278009741" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAM: 1.44-fold Down; FDR = 0.73; PValue = 0.432; mean CPM = 0.9052; integrin, alpha M (complement component 3 receptor 3 subunit)" ID="ID_444547749" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB6: 1.4-fold Down; FDR = 0.732; PValue = 0.434; mean CPM = 0.9377; Integrin beta" ID="ID_648529958" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAPGEF1: 1.05-fold Down; FDR = 0.763; PValue = 0.462; mean CPM = 70.38; Rap guanine nucleotide exchange factor (GEF) 1" ID="ID_1862416413" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRK: 1.05-fold Up; FDR = 0.791; PValue = 0.488; mean CPM = 59.92; v-crk sarcoma virus CT10 oncogene homolog (avian)" ID="ID_122825686" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DOCK1: 1.05-fold Up; FDR = 0.825; PValue = 0.524; mean CPM = 165.2; dedicator of cytokinesis 1" ID="ID_612271504" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAD: 1.66-fold Down; FDR = 0.85; PValue = 0.56; mean CPM = 0.8625; integrin, alpha D" ID="ID_11734343" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1783206847" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK7: 1.04-fold Down; FDR = 0.899; PValue = 0.632; mean CPM = 16.93; Uncharacterized protein" ID="ID_1390925136" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GIT2: 1.03-fold Up; FDR = 0.903; PValue = 0.641; mean CPM = 56.52; G protein-coupled receptor kinase interacting ArfGAP 2" ID="ID_1094616907" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAK1: 1.03-fold Down; FDR = 0.911; PValue = 0.705; mean CPM = 18.65; p21 protein (Cdc42/Rac)-activated kinase 1" ID="ID_1196842256" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAPN6: 1.12-fold Up; FDR = 0.914; PValue = 0.71; mean CPM = 1.245; calpain 6" ID="ID_1960589204" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAPN3: 1.07-fold Down; FDR = 0.921; PValue = 0.724; mean CPM = 6.384; calpain 3, (p94)" ID="ID_551087291" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_106034532" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_8653112" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAPN9: 1.14-fold Down; FDR = 1; PValue = 0.893; mean CPM = 0.8458; calpain 9" ID="ID_785232667" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK4: 1.19-fold Down; FDR = 1; PValue = 0.95; mean CPM = 0.8611; mitogen-activated protein kinase 4" ID="ID_1007014437" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGAL: 1.03-fold Up; FDR = 1; PValue = 0.95; mean CPM = 1.035; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)" ID="ID_890919226" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB7: 1.01-fold Down; FDR = 1; PValue = 0.968; mean CPM = 2.025; integrin, beta 7" ID="ID_1435878539" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV2: No Change; FDR = 1; PValue = 0.976; mean CPM = 25.65; vav 2 guanine nucleotide exchange factor" ID="ID_1812709429" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAV3: 1.02-fold Down; FDR = 1; PValue = 0.98; mean CPM = 0.7970; caveolin 3" ID="ID_1333565987" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAPN10: No Change; FDR = 1; PValue = 0.991; mean CPM = 32.48; calpain 10" ID="ID_1013478313" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Leptin signaling pathway (WP2034:Rev45589): FDR = 1.47e-07, PValue = 2.99e-08" ID="ID_990747062" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_762893093" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1375873710" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_1455514077" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_11748529" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRS1: 2.78-fold Up; FDR = 7.67e-09; PValue = 3.19e-10; mean CPM = 26.55; Uncharacterized protein" ID="ID_897083574" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CFL2: 1.88-fold Down; FDR = 1.06e-08; PValue = 4.59e-10; mean CPM = 58.30; cofilin 2 (muscle)" ID="ID_1465518999" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RELA: 1.55-fold Up; FDR = 3.47e-08; PValue = 1.74e-09; mean CPM = 86.96; v-rel reticuloendotheliosis viral oncogene homolog A (avian)" ID="ID_666369352" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ESR1: 5.04-fold Up; FDR = 6.62e-08; PValue = 3.55e-09; mean CPM = 2.845; estrogen receptor 1" ID="ID_1810725065" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SH2B1: 1.53-fold Down; FDR = 1.95e-07; PValue = 1.17e-08; mean CPM = 35.01; SH2B adaptor protein 1" ID="ID_840356988" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_660636840" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L1: 1.51-fold Up; FDR = 9.13e-07; PValue = 6.52e-08; mean CPM = 66.15; Bcl-2-like protein 1; Bcl-2-like protein 1 isoform 1; Uncharacterized protein" ID="ID_1427048622" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1214594377" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_1888514354" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1RN: 3.51-fold Up; FDR = 1.4e-05; PValue = 1.36e-06; mean CPM = 9.467; interleukin 1 receptor antagonist" ID="ID_980042585" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_360327876" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS3: 1.69-fold Up; FDR = 0.000994; PValue = 0.000167; mean CPM = 37.76; suppressor of cytokine signaling 3" ID="ID_1394095427" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOXO1: 1.49-fold Down; FDR = 0.00109; PValue = 0.000186; mean CPM = 11.95; forkhead box O1" ID="ID_1813406252" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CISH: 1.95-fold Up; FDR = 0.00116; PValue = 0.0002; mean CPM = 5.083; cytokine inducible SH2-containing protein" ID="ID_1665819515" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTOR: 1.3-fold Down; FDR = 0.00117; PValue = 0.000201; mean CPM = 107.5; mechanistic target of rapamycin (serine/threonine kinase)" ID="ID_477164290" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="REL: 1.46-fold Down; FDR = 0.00272; PValue = 0.000526; mean CPM = 10.17; v-rel avian reticuloendotheliosis viral oncogene homolog" ID="ID_1216073060" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHOA: 1.28-fold Down; FDR = 0.00295; PValue = 0.000575; mean CPM = 277.8; ras homolog gene family, member A" ID="ID_1702054821" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG1: 1.31-fold Down; FDR = 0.00352; PValue = 0.000707; mean CPM = 53.66; phospholipase C, gamma 1" ID="ID_1227775095" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACACA: 1.27-fold Down; FDR = 0.00395; PValue = 0.000809; mean CPM = 54.13; acetyl-CoA carboxylase alpha" ID="ID_1345469829" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KPNA4: 1.25-fold Up; FDR = 0.00667; PValue = 0.00148; mean CPM = 61.65; karyopherin alpha 4 (importin alpha 3)" ID="ID_96698206" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SP1: 1.23-fold Up; FDR = 0.0139; PValue = 0.00344; mean CPM = 75.49; Transcription factor Sp1 isoform a; Uncharacterized protein" ID="ID_312775401" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KHDRBS1: 1.23-fold Down; FDR = 0.0146; PValue = 0.00364; mean CPM = 58.38; KH domain containing, RNA binding, signal transduction associated 1" ID="ID_1203433121" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FYN: 1.22-fold Up; FDR = 0.0156; PValue = 0.00393; mean CPM = 92.94; FYN oncogene related to SRC, FGR, YES" ID="ID_176587446" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS2: 1.31-fold Down; FDR = 0.0188; PValue = 0.0049; mean CPM = 35.29; suppressor of cytokine signaling 2" ID="ID_1447966441" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1321171954" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_77344689" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB1: 1.21-fold Up; FDR = 0.0313; PValue = 0.00884; mean CPM = 36.07; cAMP responsive element binding protein 1" ID="ID_458112692" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_66424173" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LEP: 1.67-fold Down; FDR = 0.0401; PValue = 0.0118; mean CPM = 63.70; leptin" ID="ID_737148074" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN1: 1.2-fold Down; FDR = 0.0495; PValue = 0.0152; mean CPM = 35.05; protein tyrosine phosphatase, non-receptor type 1" ID="ID_1175537538" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_33564209" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_1624155820" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCOA1: 1.18-fold Up; FDR = 0.112; PValue = 0.04; mean CPM = 20.42; nuclear receptor coactivator 1" ID="ID_503578618" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IKBKB: 1.16-fold Up; FDR = 0.116; PValue = 0.0418; mean CPM = 44.75; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta" ID="ID_960921454" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND1: 1.17-fold Up; FDR = 0.121; PValue = 0.0443; mean CPM = 867.3; cyclin D1" ID="ID_246788187" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_165171669" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_995141578" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ERBB2: 1.14-fold Down; FDR = 0.23; PValue = 0.0977; mean CPM = 119.0; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)" ID="ID_1855953743" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1012968458" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_1169249628" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_1159947354" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LEPR: 1.52-fold Down; FDR = 0.489; PValue = 0.251; mean CPM = 1.051; leptin receptor" ID="ID_1674957878" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDE3B: 1.54-fold Up; FDR = 0.568; PValue = 0.307; mean CPM = 0.9109; Uncharacterized protein" ID="ID_1081764788" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6: 1.08-fold Up; FDR = 0.584; PValue = 0.318; mean CPM = 892.5; ribosomal protein S6" ID="ID_833981881" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDC42: 1.07-fold Down; FDR = 0.608; PValue = 0.335; mean CPM = 91.67; cell division cycle 42" ID="ID_626093295" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IL1B: 1.38-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 36.01; interleukin 1, beta" ID="ID_845806356" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAX: 1.05-fold Up; FDR = 0.809; PValue = 0.506; mean CPM = 162.4; Uncharacterized protein" ID="ID_930020387" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOCS7: 1.07-fold Down; FDR = 0.847; PValue = 0.556; mean CPM = 7.514; suppressor of cytokine signaling 7" ID="ID_1037618878" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CHUK: 1.04-fold Up; FDR = 0.858; PValue = 0.572; mean CPM = 45.34; conserved helix-loop-helix ubiquitous kinase" ID="ID_643934551" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_411493497" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB1: 1.04-fold Up; FDR = 0.88; PValue = 0.6; mean CPM = 30.80; Uncharacterized protein" ID="ID_1823298064" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_95906330" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_1230999159" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="DNA damage response (only ATM dependent) (WP710:Rev45197): FDR = 1.85e-07, PValue = 3.85e-08" ID="ID_287209306" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="MLKL: 8.31-fold Up; FDR = 6.73e-21; PValue = 2.09e-23; mean CPM = 34.78; mixed lineage kinase domain-like" ID="ID_1497288024" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PMAIP1: 8.66-fold Up; FDR = 1.12e-12; PValue = 1.84e-14; mean CPM = 31.02; Phorbol-12-myristate-13-acetate-induced protein 1; Uncharacterized protein" ID="ID_804796735" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND3: 2.27-fold Down; FDR = 8.38e-11; PValue = 2.15e-12; mean CPM = 86.90; cyclin D3" ID="ID_1146520229" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLAU: 3.37-fold Down; FDR = 1.56e-10; PValue = 4.33e-12; mean CPM = 18.78; plasminogen activator, urokinase" ID="ID_1322258915" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAT: 1.75-fold Up; FDR = 1.21e-09; PValue = 4.14e-11; mean CPM = 42.72; catalase" ID="ID_516442140" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_1426173367" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRS1: 2.78-fold Up; FDR = 7.67e-09; PValue = 3.19e-10; mean CPM = 26.55; Uncharacterized protein" ID="ID_38934079" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1B: 1.64-fold Up; FDR = 1.22e-08; PValue = 5.39e-10; mean CPM = 32.96; Cyclin-dependent kinase inhibitor 1B; Uncharacterized protein" ID="ID_1657421320" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INSR: 1.93-fold Down; FDR = 1.24e-08; PValue = 5.48e-10; mean CPM = 118.3; insulin receptor" ID="ID_965291685" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOD2: 4.88-fold Up; FDR = 1.73e-08; PValue = 7.93e-10; mean CPM = 558.4; superoxide dismutase 2, mitochondrial" ID="ID_283691882" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCNG2: 1.58-fold Up; FDR = 2.55e-07; PValue = 1.56e-08; mean CPM = 45.06; cyclin G2" ID="ID_267995755" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1934513850" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT5A: 1.65-fold Down; FDR = 2.5e-05; PValue = 2.59e-06; mean CPM = 136.4; wingless-type MMTV integration site family, member 5A" ID="ID_1715284125" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000009315: 1.44-fold Down; FDR = 4.44e-05; PValue = 4.94e-06; mean CPM = 22.79" ID="ID_290134493" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PCK2: 1.8-fold Up; FDR = 8.33e-05; PValue = 1.01e-05; mean CPM = 110.4; phosphoenolpyruvate carboxykinase 2 (mitochondrial)" ID="ID_474951318" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SCP2: 1.34-fold Up; FDR = 0.000258; PValue = 3.65e-05; mean CPM = 107.5; sterol carrier protein 2" ID="ID_280749374" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_205299538" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD3: 1.38-fold Up; FDR = 0.000573; PValue = 8.94e-05; mean CPM = 114.9; SMAD family member 3" ID="ID_307379069" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAD: 1.36-fold Down; FDR = 0.000605; PValue = 9.52e-05; mean CPM = 48.46; BCL2-associated agonist of cell death" ID="ID_291423997" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT1: 7.1-fold Down; FDR = 0.000659; PValue = 0.000105; mean CPM = 2.664; wingless-type MMTV integration site family, member 1" ID="ID_1672647293" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DVL3: 1.29-fold Down; FDR = 0.00157; PValue = 0.00028; mean CPM = 67.95; dishevelled, dsh homolog 3 (Drosophila)" ID="ID_1807703307" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHOA: 1.28-fold Down; FDR = 0.00295; PValue = 0.000575; mean CPM = 277.8; ras homolog gene family, member A" ID="ID_1741516683" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MDM2: 1.32-fold Up; FDR = 0.00555; PValue = 0.00119; mean CPM = 148.6; Uncharacterized protein" ID="ID_243767624" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK10: 3.55-fold Down; FDR = 0.00598; PValue = 0.0013; mean CPM = 1.032; mitogen-activated protein kinase 10" ID="ID_660313096" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT7A: 3.46-fold Down; FDR = 0.00638; PValue = 0.0014; mean CPM = 1.036; wingless-type MMTV integration site family, member 7A" ID="ID_1770033019" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT10A: 4.08-fold Down; FDR = 0.00805; PValue = 0.00183; mean CPM = 0.9138; wingless-type MMTV integration site family, member 10A" ID="ID_693176483" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT5B: 1.58-fold Down; FDR = 0.00866; PValue = 0.002; mean CPM = 7.832; wingless-type MMTV integration site family, member 5B" ID="ID_1771774288" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT10B: 3.1-fold Down; FDR = 0.0148; PValue = 0.00369; mean CPM = 1.086; wingless-type MMTV integration site family, member 10B" ID="ID_1529036627" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_1392673258" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC2: 2.96-fold Up; FDR = 0.0309; PValue = 0.00872; mean CPM = 0.9737; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)" ID="ID_1870499841" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTNNB1: 1.2-fold Up; FDR = 0.0498; PValue = 0.0153; mean CPM = 558.3; catenin (cadherin-associated protein), beta 1, 88kDa" ID="ID_986613934" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT4: 1.52-fold Down; FDR = 0.0525; PValue = 0.0163; mean CPM = 13.66; wingless-type MMTV integration site family, member 4" ID="ID_1297444594" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP73: 2.3-fold Down; FDR = 0.0601; PValue = 0.0192; mean CPM = 1.058; tumor protein p73" ID="ID_1480096979" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2L11: 1.34-fold Up; FDR = 0.0609; PValue = 0.0195; mean CPM = 18.38; BCL2-like 11 (apoptosis facilitator)" ID="ID_847271515" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_774481316" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS2: 1.17-fold Up; FDR = 0.1; PValue = 0.0353; mean CPM = 31.79; son of sevenless homolog 2 (Drosophila)" ID="ID_958476856" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R5E: 1.17-fold Up; FDR = 0.112; PValue = 0.04; mean CPM = 30.87; Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform; Uncharacterized protein" ID="ID_1140887951" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND1: 1.17-fold Up; FDR = 0.121; PValue = 0.0443; mean CPM = 867.3; cyclin D1" ID="ID_710090387" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_828966384" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_1547579768" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_579959823" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTEN: 1.14-fold Up; FDR = 0.166; PValue = 0.065; mean CPM = 89.60; phosphatase and tensin homolog" ID="ID_1599075670" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1655899097" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT3A: 2.28-fold Down; FDR = 0.2; PValue = 0.0823; mean CPM = 0.8811; wingless-type MMTV integration site family, member 3A" ID="ID_1437280652" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_1146015671" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ERBB2: 1.14-fold Down; FDR = 0.23; PValue = 0.0977; mean CPM = 119.0; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)" ID="ID_1395754285" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1A: 1.16-fold Down; FDR = 0.28; PValue = 0.124; mean CPM = 363.2; Cyclin-dependent kinase inhibitor 1; Uncharacterized protein" ID="ID_687384647" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K4: 1.13-fold Down; FDR = 0.284; PValue = 0.126; mean CPM = 25.34; Uncharacterized protein" ID="ID_1669208834" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT3: 1.4-fold Up; FDR = 0.304; PValue = 0.138; mean CPM = 1.843; wingless-type MMTV integration site family, member 3" ID="ID_1477338619" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND2: 1.2-fold Up; FDR = 0.335; PValue = 0.155; mean CPM = 76.91; cyclin D2" ID="ID_238899483" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TP53: 1.11-fold Down; FDR = 0.364; PValue = 0.172; mean CPM = 33.25; tumor protein p53" ID="ID_433257075" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APC: 1.1-fold Down; FDR = 0.367; PValue = 0.174; mean CPM = 127.5; adenomatous polyposis coli" ID="ID_135203210" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL2: 1.48-fold Up; FDR = 0.384; PValue = 0.184; mean CPM = 1.344; Uncharacterized protein" ID="ID_836936356" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPP2R5C: 1.14-fold Up; FDR = 0.391; PValue = 0.189; mean CPM = 54.95; protein phosphatase 2, regulatory subunit B', gamma" ID="ID_1116480297" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ABL1: 1.09-fold Up; FDR = 0.43; PValue = 0.213; mean CPM = 178.0; c-abl oncogene 1, receptor tyrosine kinase" ID="ID_137090036" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RBL2: 1.09-fold Up; FDR = 0.445; PValue = 0.222; mean CPM = 47.90; retinoblastoma-like 2 (p130)" ID="ID_238035293" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOXO3: 1.08-fold Down; FDR = 0.55; PValue = 0.294; mean CPM = 48.45; forkhead box O3" ID="ID_522237640" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDC42: 1.07-fold Down; FDR = 0.608; PValue = 0.335; mean CPM = 91.67; cell division cycle 42" ID="ID_814244307" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT2B: 1.29-fold Down; FDR = 0.621; PValue = 0.345; mean CPM = 1.575; wingless-type MMTV integration site family, member 2B" ID="ID_653884250" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AXIN1: 1.06-fold Up; FDR = 0.661; PValue = 0.376; mean CPM = 66.56; axin 1" ID="ID_64317101" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATM: 1.06-fold Down; FDR = 0.67; PValue = 0.383; mean CPM = 65.17; ataxia telangiectasia mutated" ID="ID_268265027" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DVL2: 1.06-fold Up; FDR = 0.708; PValue = 0.414; mean CPM = 30.54; dishevelled, dsh homolog 2 (Drosophila)" ID="ID_1601881449" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BIK: 1.2-fold Down; FDR = 0.797; PValue = 0.494; mean CPM = 1.495; BCL2-interacting killer (apoptosis-inducing)" ID="ID_750521059" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BAX: 1.05-fold Up; FDR = 0.809; PValue = 0.506; mean CPM = 162.4; Uncharacterized protein" ID="ID_1023275835" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCL6: 1.06-fold Down; FDR = 0.837; PValue = 0.542; mean CPM = 64.49; B-cell CLL/lymphoma 6" ID="ID_35950660" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LDLR: 1.07-fold Down; FDR = 0.854; PValue = 0.567; mean CPM = 167.3; low density lipoprotein receptor" ID="ID_1525038509" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT16: 1.27-fold Down; FDR = 0.857; PValue = 0.571; mean CPM = 0.9003; wingless-type MMTV integration site family, member 16" ID="ID_625462243" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT11: 1.18-fold Up; FDR = 0.903; PValue = 0.641; mean CPM = 1.340; wingless-type MMTV integration site family, member 11" ID="ID_82201632" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOSL1: 1.04-fold Up; FDR = 0.903; PValue = 0.657; mean CPM = 64.19; FOS-like antigen 1" ID="ID_572730046" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD4: 1.03-fold Down; FDR = 0.906; PValue = 0.666; mean CPM = 43.02; SMAD family member 4" ID="ID_901496168" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="G6PC: 1.22-fold Down; FDR = 0.929; PValue = 0.737; mean CPM = 0.8105; glucose-6-phosphatase, catalytic subunit" ID="ID_1715158235" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TGFB1: 1.02-fold Down; FDR = 0.936; PValue = 0.749; mean CPM = 62.61; transforming growth factor, beta 1" ID="ID_1344789964" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FASLG: 1.2-fold Down; FDR = 0.941; PValue = 0.757; mean CPM = 0.8088; Fas ligand (TNF superfamily, member 6)" ID="ID_416056100" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_474754954" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K7: 1.02-fold Down; FDR = 0.972; PValue = 0.814; mean CPM = 39.43; mitogen-activated protein kinase kinase kinase 7" ID="ID_6609718" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT2: 1.07-fold Down; FDR = 1; PValue = 0.888; mean CPM = 0.8103; wingless-type MMTV integration site family member 2" ID="ID_1311697020" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT6: 1.13-fold Down; FDR = 1; PValue = 0.956; mean CPM = 0.8230; wingless-type MMTV integration site family, member 6" ID="ID_414571312" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Pentose Phosphate Pathway (WP134:Rev45148): FDR = 1.86e-07, PValue = 3.96e-08" ID="ID_801421880" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="RPE: 1.91-fold Up; FDR = 2.36e-08; PValue = 1.13e-09; mean CPM = 46.08; Uncharacterized protein" ID="ID_1097337749" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TALDO1: 1.54-fold Up; FDR = 7.36e-08; PValue = 3.98e-09; mean CPM = 328.4; transaldolase 1" ID="ID_1550711842" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PGD: 1.25-fold Up; FDR = 0.0187; PValue = 0.00485; mean CPM = 117.1; phosphogluconate dehydrogenase" ID="ID_756134816" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PGLS: 1.21-fold Down; FDR = 0.0234; PValue = 0.00632; mean CPM = 66.37; 6-phosphogluconolactonase" ID="ID_32453580" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPIA: 1.21-fold Up; FDR = 0.184; PValue = 0.0738; mean CPM = 8.695; ribose 5-phosphate isomerase A" ID="ID_744239961" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Notch Signaling Pathway (WP61:Rev45344): FDR = 2.65e-07, PValue = 5.85e-08" ID="ID_1293468525" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_678216568" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RBPJ: 2.84-fold Up; FDR = 1.11e-14; PValue = 1.22e-16; mean CPM = 158.0; recombination signal binding protein for immunoglobulin kappa J region" ID="ID_882796485" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOTCH3: 6.31-fold Down; FDR = 2.33e-13; PValue = 3.29e-15; mean CPM = 185.7; Notch homolog 3 (Drosophila)" ID="ID_567819927" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CIR1: 2.06-fold Up; FDR = 4.17e-13; PValue = 6.26e-15; mean CPM = 41.48; corepressor interacting with RBPJ, 1" ID="ID_590028453" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NUMBL: 2.15-fold Down; FDR = 2.64e-11; PValue = 6.08e-13; mean CPM = 22.15; numb homolog (Drosophila)-like" ID="ID_1979888030" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_937205662" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAG1: 2.62-fold Down; FDR = 3.16e-08; PValue = 1.56e-09; mean CPM = 175.2; jagged 1" ID="ID_297173100" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SAP30: 2.14-fold Up; FDR = 6.14e-08; PValue = 3.28e-09; mean CPM = 10.69; Histone deacetylase complex subunit SAP30; Uncharacterized protein" ID="ID_770251903" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1024933344" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HEY1: 4.88-fold Down; FDR = 7.84e-07; PValue = 5.48e-08; mean CPM = 1.952; hairy/enhancer-of-split related with YRPW motif 1" ID="ID_1244533928" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HES1: 2.4-fold Down; FDR = 5.84e-06; PValue = 5.13e-07; mean CPM = 75.36; hairy and enhancer of split 1, (Drosophila)" ID="ID_1973580631" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPT: 2.89-fold Down; FDR = 3.14e-05; PValue = 3.34e-06; mean CPM = 2.105; microtubule-associated protein tau" ID="ID_1237593727" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADAM17: 1.32-fold Up; FDR = 0.00063; PValue = 9.95e-05; mean CPM = 118.8; ADAM metallopeptidase domain 17" ID="ID_120744552" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GATA3: 2.81-fold Up; FDR = 0.000734; PValue = 0.000119; mean CPM = 2.229; GATA binding protein 3" ID="ID_923806860" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APH1B: 1.39-fold Up; FDR = 0.000776; PValue = 0.000126; mean CPM = 17.84; anterior pharynx defective 1 homolog B (C. elegans)" ID="ID_1515868997" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000039874: 1.3-fold Up; FDR = 0.001; PValue = 0.000168; mean CPM = 80.13; Uncharacterized protein" ID="ID_266883770" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSENEN: 1.31-fold Up; FDR = 0.00118; PValue = 0.000203; mean CPM = 76.54; presenilin enhancer 2 homolog (C. elegans)" ID="ID_553108163" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOTCH1: 1.44-fold Down; FDR = 0.0032; PValue = 0.000634; mean CPM = 32.99; Notch homolog 1, translocation-associated (Drosophila)" ID="ID_632140936" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CUL1: 1.24-fold Up; FDR = 0.0104; PValue = 0.00247; mean CPM = 106.1; cullin 1" ID="ID_746693799" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC1: 1.25-fold Up; FDR = 0.0159; PValue = 0.00403; mean CPM = 27.51; histone deacetylase 1" ID="ID_1228469737" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1200015756" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAML1: 1.23-fold Down; FDR = 0.0266; PValue = 0.00733; mean CPM = 45.38; mastermind-like 1 (Drosophila)" ID="ID_304893655" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCSTN: 1.21-fold Up; FDR = 0.0284; PValue = 0.0079; mean CPM = 205.1; nicastrin" ID="ID_1094112047" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_572040352" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DTX1: 2.82-fold Down; FDR = 0.0473; PValue = 0.0144; mean CPM = 0.9361; deltex homolog 1 (Drosophila)" ID="ID_1405900473" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPEN: 1.18-fold Down; FDR = 0.0585; PValue = 0.0185; mean CPM = 128.1; spen family transcriptional repressor" ID="ID_1916802095" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_736215590" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DLL1: 1.66-fold Up; FDR = 0.0898; PValue = 0.0308; mean CPM = 2.702; delta-like 1 (Drosophila)" ID="ID_1745182104" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FHL1: 1.23-fold Up; FDR = 0.0938; PValue = 0.0325; mean CPM = 85.43; four and a half LIM domains 1" ID="ID_1738494081" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC2: 1.15-fold Up; FDR = 0.115; PValue = 0.0414; mean CPM = 93.64; histone deacetylase 2" ID="ID_473992036" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CCND1: 1.17-fold Up; FDR = 0.121; PValue = 0.0443; mean CPM = 867.3; cyclin D1" ID="ID_1039452269" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_1738438440" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RING1: 1.14-fold Down; FDR = 0.155; PValue = 0.0598; mean CPM = 54.55; ring finger protein 1" ID="ID_595577065" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SKP1: 1.14-fold Up; FDR = 0.176; PValue = 0.07; mean CPM = 88.20; S-phase kinase-associated protein 1" ID="ID_1162492202" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FBXW7: 1.17-fold Down; FDR = 0.181; PValue = 0.0727; mean CPM = 33.48; F-box and WD repeat domain containing 7" ID="ID_624374286" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DLL4: 1.82-fold Down; FDR = 0.2; PValue = 0.0824; mean CPM = 1.928; delta-like 4 (Drosophila)" ID="ID_1220946387" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HES6: 1.71-fold Down; FDR = 0.214; PValue = 0.0895; mean CPM = 1.226; hairy and enhancer of split 6 (Drosophila)" ID="ID_1576413674" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000041158: 1.15-fold Up; FDR = 0.216; PValue = 0.0905; mean CPM = 24.28; Uncharacterized protein" ID="ID_959064567" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSEN1: 1.12-fold Up; FDR = 0.233; PValue = 0.0992; mean CPM = 62.12; presenilin 1" ID="ID_1900544382" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDKN1A: 1.16-fold Down; FDR = 0.28; PValue = 0.124; mean CPM = 363.2; Cyclin-dependent kinase inhibitor 1; Uncharacterized protein" ID="ID_1314910714" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EP300: 1.11-fold Up; FDR = 0.312; PValue = 0.142; mean CPM = 162.8; E1A binding protein p300" ID="ID_1065400897" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PSEN2: 1.11-fold Down; FDR = 0.445; PValue = 0.222; mean CPM = 23.33; Uncharacterized protein" ID="ID_973404167" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAG2: 1.26-fold Down; FDR = 0.511; PValue = 0.266; mean CPM = 3.134; Delta-like protein" ID="ID_586762865" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HEY2: 1.61-fold Down; FDR = 0.514; PValue = 0.268; mean CPM = 0.9173; hairy/enhancer-of-split related with YRPW motif 2" ID="ID_1087249074" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOTCH2: 1.09-fold Down; FDR = 0.514; PValue = 0.268; mean CPM = 795.0; Notch homolog 2 (Drosophila)" ID="ID_1275129721" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTCRA: 1.99-fold Down; FDR = 0.68; PValue = 0.391; mean CPM = 0.8703; pre T-cell antigen receptor alpha" ID="ID_193994842" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DLL3: 1.09-fold Down; FDR = 0.808; PValue = 0.504; mean CPM = 5.871; delta-like 3 (Drosophila)" ID="ID_283370416" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="APH1A: 1.05-fold Up; FDR = 0.828; PValue = 0.529; mean CPM = 85.70; anterior pharynx defective 1 homolog A (C. elegans)" ID="ID_280644794" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NUMB: 1.03-fold Up; FDR = 0.909; PValue = 0.687; mean CPM = 60.96; numb homolog (Drosophila)" ID="ID_1658000023" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAGEA1: No Change; FDR = 1; PValue = 1; mean CPM = 0.7818; melanoma antigen family A, 1 (directs expression of antigen MZ2-E)" ID="ID_209367678" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Neural Crest Differentiation (WP2064:Rev45584): FDR = 2.65e-07, PValue = 5.93e-08" ID="ID_161928289" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="RBPJ: 2.84-fold Up; FDR = 1.11e-14; PValue = 1.22e-16; mean CPM = 158.0; recombination signal binding protein for immunoglobulin kappa J region" ID="ID_1701992432" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOTCH3: 6.31-fold Down; FDR = 2.33e-13; PValue = 3.29e-15; mean CPM = 185.7; Notch homolog 3 (Drosophila)" ID="ID_638115891" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHOB: 2.87-fold Down; FDR = 2.74e-13; PValue = 3.96e-15; mean CPM = 84.32; ras homolog gene family, member B" ID="ID_1364053940" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDH2: 2.24-fold Down; FDR = 2.51e-10; PValue = 7.39e-12; mean CPM = 402.4; cadherin 2, type 1, N-cadherin (neuronal)" ID="ID_17886743" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC5: 1.72-fold Down; FDR = 2.07e-09; PValue = 7.53e-11; mean CPM = 122.7; histone deacetylase 5" ID="ID_431717015" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF2: 2.42-fold Up; FDR = 9.98e-09; PValue = 4.31e-10; mean CPM = 134.8; fibroblast growth factor 2 (basic)" ID="ID_23387692" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGFR2: 3.45-fold Down; FDR = 1.04e-08; PValue = 4.53e-10; mean CPM = 5.064; fibroblast growth factor receptor 2" ID="ID_1467263931" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC9: 4.18-fold Down; FDR = 2.74e-08; PValue = 1.34e-09; mean CPM = 25.34; histone deacetylase 9" ID="ID_70160221" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOX9: 3.15-fold Down; FDR = 1.96e-06; PValue = 1.53e-07; mean CPM = 6.885; SRY (sex determining region Y)-box 9" ID="ID_1540173026" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGFR3: 3.85-fold Down; FDR = 2.66e-06; PValue = 2.13e-07; mean CPM = 2.800; fibroblast growth factor receptor 3" ID="ID_1321339408" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HES1: 2.4-fold Down; FDR = 5.84e-06; PValue = 5.13e-07; mean CPM = 75.36; hairy and enhancer of split 1, (Drosophila)" ID="ID_1821466679" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000009315: 1.44-fold Down; FDR = 4.44e-05; PValue = 4.94e-06; mean CPM = 22.79" ID="ID_210631275" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC7: 1.43-fold Down; FDR = 5.36e-05; PValue = 6.14e-06; mean CPM = 25.32; Uncharacterized protein" ID="ID_658118052" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AXIN2: 3.75-fold Down; FDR = 6.09e-05; PValue = 7.1e-06; mean CPM = 2.690; axin 2" ID="ID_785543643" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB2: 1.36-fold Down; FDR = 0.000106; PValue = 1.32e-05; mean CPM = 122.8; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)" ID="ID_1136280394" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000028518: 1.35-fold Down; FDR = 0.000199; PValue = 2.72e-05; mean CPM = 42.49" ID="ID_153325749" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT1: 7.1-fold Down; FDR = 0.000659; PValue = 0.000105; mean CPM = 2.664; wingless-type MMTV integration site family, member 1" ID="ID_574264179" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DVL3: 1.29-fold Down; FDR = 0.00157; PValue = 0.00028; mean CPM = 67.95; dishevelled, dsh homolog 3 (Drosophila)" ID="ID_399464158" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ID1: 1.64-fold Down; FDR = 0.00178; PValue = 0.000326; mean CPM = 22.90; inhibitor of DNA binding 1, dominant negative helix-loop-helix protein" ID="ID_438816203" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOTCH1: 1.44-fold Down; FDR = 0.0032; PValue = 0.000634; mean CPM = 32.99; Notch homolog 1, translocation-associated (Drosophila)" ID="ID_1118107038" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC4: 1.38-fold Down; FDR = 0.00526; PValue = 0.00112; mean CPM = 48.60; histone deacetylase 4" ID="ID_297692792" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC1: 1.25-fold Up; FDR = 0.0159; PValue = 0.00403; mean CPM = 27.51; histone deacetylase 1" ID="ID_955604155" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTBP2: 1.23-fold Up; FDR = 0.0166; PValue = 0.00423; mean CPM = 49.75; C-terminal binding protein 2" ID="ID_925395750" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL2A1: 2.38-fold Down; FDR = 0.0368; PValue = 0.0107; mean CPM = 1.117; Uncharacterized protein" ID="ID_202271306" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NFKB1: 1.2-fold Down; FDR = 0.039; PValue = 0.0115; mean CPM = 72.10; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1" ID="ID_340499670" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MBP: 1.5-fold Up; FDR = 0.0433; PValue = 0.013; mean CPM = 3.435; myelin basic protein" ID="ID_764241549" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC6: 1.21-fold Down; FDR = 0.0436; PValue = 0.0131; mean CPM = 30.86; histone deacetylase 6" ID="ID_1961569488" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTNNB1: 1.2-fold Up; FDR = 0.0498; PValue = 0.0153; mean CPM = 558.3; catenin (cadherin-associated protein), beta 1, 88kDa" ID="ID_1588122768" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYC: 1.18-fold Up; FDR = 0.0688; PValue = 0.0225; mean CPM = 161.3; Macaca mulatta v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mRNA." ID="ID_1038394293" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB1: 1.23-fold Up; FDR = 0.0759; PValue = 0.0253; mean CPM = 2700; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)" ID="ID_495450981" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TCF7L1: 1.2-fold Down; FDR = 0.0783; PValue = 0.0262; mean CPM = 25.11; transcription factor 7-like 1 (T-cell specific, HMG-box)" ID="ID_580649743" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DLL1: 1.66-fold Up; FDR = 0.0898; PValue = 0.0308; mean CPM = 2.702; delta-like 1 (Drosophila)" ID="ID_1141882602" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ETS1: 1.16-fold Up; FDR = 0.0996; PValue = 0.0348; mean CPM = 94.27; v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)" ID="ID_928149870" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC2: 1.15-fold Up; FDR = 0.115; PValue = 0.0414; mean CPM = 93.64; histone deacetylase 2" ID="ID_691765087" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BMP4: 1.86-fold Down; FDR = 0.119; PValue = 0.0432; mean CPM = 2.163; bone morphogenetic protein 4" ID="ID_1493164120" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TCF4: 1.23-fold Down; FDR = 0.119; PValue = 0.0434; mean CPM = 34.08; transcription factor 4" ID="ID_1765841221" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYB: 1.85-fold Down; FDR = 0.12; PValue = 0.0437; mean CPM = 1.320; v-myb myeloblastosis viral oncogene homolog (avian)" ID="ID_1455933937" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SNAI2: 1.27-fold Up; FDR = 0.127; PValue = 0.0468; mean CPM = 55.60; snail homolog 2 (Drosophila)" ID="ID_297180021" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MIA: 1.59-fold Down; FDR = 0.131; PValue = 0.049; mean CPM = 1.895; melanoma inhibitory activity" ID="ID_1402496840" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSK3B: 1.18-fold Up; FDR = 0.137; PValue = 0.0515; mean CPM = 16.89; glycogen synthase kinase 3 beta" ID="ID_1828257654" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGFR1: 1.15-fold Down; FDR = 0.139; PValue = 0.0525; mean CPM = 89.41; fibroblast growth factor receptor 1" ID="ID_544223860" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="WNT3A: 2.28-fold Down; FDR = 0.2; PValue = 0.0823; mean CPM = 0.8811; wingless-type MMTV integration site family, member 3A" ID="ID_910488206" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DLL4: 1.82-fold Down; FDR = 0.2; PValue = 0.0824; mean CPM = 1.928; delta-like 4 (Drosophila)" ID="ID_1142114937" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MSX1: 1.21-fold Up; FDR = 0.234; PValue = 0.1; mean CPM = 8.298; msh homeobox 1" ID="ID_647075740" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TWIST1: 1.18-fold Up; FDR = 0.24; PValue = 0.103; mean CPM = 10.19; Twist-like protein; Uncharacterized protein" ID="ID_1285987006" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DLX5: 1.18-fold Down; FDR = 0.267; PValue = 0.117; mean CPM = 9.099; distal-less homeobox 5" ID="ID_185308000" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PMP22: 1.17-fold Up; FDR = 0.326; PValue = 0.15; mean CPM = 16.49; peripheral myelin protein 22" ID="ID_1708875983" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DCT: 1.48-fold Down; FDR = 0.397; PValue = 0.192; mean CPM = 1.362; dopachrome tautomerase" ID="ID_1295047030" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC10: 1.1-fold Down; FDR = 0.489; PValue = 0.251; mean CPM = 21.21; Uncharacterized protein" ID="ID_307790762" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HEY2: 1.61-fold Down; FDR = 0.514; PValue = 0.268; mean CPM = 0.9173; hairy/enhancer-of-split related with YRPW motif 2" ID="ID_1099237677" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NOTCH2: 1.09-fold Down; FDR = 0.514; PValue = 0.268; mean CPM = 795.0; Notch homolog 2 (Drosophila)" ID="ID_882021114" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOX5: 1.4-fold Up; FDR = 0.536; PValue = 0.284; mean CPM = 1.420; SRY (sex determining region Y)-box 5" ID="ID_995722281" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AXIN1: 1.06-fold Up; FDR = 0.661; PValue = 0.376; mean CPM = 66.56; axin 1" ID="ID_1401783562" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DVL2: 1.06-fold Up; FDR = 0.708; PValue = 0.414; mean CPM = 30.54; dishevelled, dsh homolog 2 (Drosophila)" ID="ID_1083692874" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAX7: 1.69-fold Down; FDR = 0.748; PValue = 0.448; mean CPM = 0.8228; paired box 7" ID="ID_349494823" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC8: 1.06-fold Up; FDR = 0.76; PValue = 0.459; mean CPM = 20.83; histone deacetylase 8" ID="ID_1294468458" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SMAD1: 1.07-fold Up; FDR = 0.768; PValue = 0.466; mean CPM = 16.45; SMAD family member 1" ID="ID_188484987" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF8: 1.75-fold Down; FDR = 0.783; PValue = 0.48; mean CPM = 0.8245; Uncharacterized protein" ID="ID_657259422" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DLL3: 1.09-fold Down; FDR = 0.808; PValue = 0.504; mean CPM = 5.871; delta-like 3 (Drosophila)" ID="ID_391387816" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZIC5: 1.46-fold Down; FDR = 0.812; PValue = 0.509; mean CPM = 0.8013; Uncharacterized protein" ID="ID_170439444" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDH7: 1.35-fold Down; FDR = 0.82; PValue = 0.518; mean CPM = 0.7981; cadherin 7, type 2" ID="ID_690883951" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NEUROG1: 1.38-fold Down; FDR = 0.836; PValue = 0.541; mean CPM = 0.8016; neurogenin 1" ID="ID_1268709494" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TFAP2A: 1.11-fold Up; FDR = 0.845; PValue = 0.554; mean CPM = 2.800; transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)" ID="ID_264899758" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MSX2: 1.5-fold Up; FDR = 0.885; PValue = 0.606; mean CPM = 0.8397; msh homeobox 2" ID="ID_240174763" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ISL1: 1.42-fold Down; FDR = 0.895; PValue = 0.619; mean CPM = 0.8317; ISL LIM homeobox 1" ID="ID_318160261" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDH6: 1.05-fold Up; FDR = 0.903; PValue = 0.658; mean CPM = 133.6; cadherin 6, type 2, K-cadherin (fetal kidney)" ID="ID_212660279" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="OLIG2: 1.2-fold Up; FDR = 0.906; PValue = 0.668; mean CPM = 0.7937; oligodendrocyte lineage transcription factor 2" ID="ID_1395014113" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FGF19: 1.33-fold Down; FDR = 0.921; PValue = 0.724; mean CPM = 0.8101; fibroblast growth factor 19" ID="ID_501239271" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CTBP2: 1.24-fold Up; FDR = 0.934; PValue = 0.746; mean CPM = 0.8168; C-terminal binding protein 2" ID="ID_524822623" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZIC1: 1.13-fold Down; FDR = 0.948; PValue = 0.771; mean CPM = 0.9532; Zic family member 1 (odd-paired homolog, Drosophila)" ID="ID_742779121" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PHOX2B: 1.12-fold Up; FDR = 0.948; PValue = 0.771; mean CPM = 0.8064; paired-like homeobox 2b" ID="ID_714189108" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ASCL1: 1.19-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 0.8400; achaete-scute complex homolog 1 (Drosophila)" ID="ID_1430188355" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HDAC3: 1.01-fold Up; FDR = 1; PValue = 0.861; mean CPM = 41.13; histone deacetylase 3" ID="ID_1008096919" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="COL11A2: 1.03-fold Down; FDR = 1; PValue = 0.872; mean CPM = 2.131; collagen, type XI, alpha 2" ID="ID_418268870" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDH1: 1.06-fold Down; FDR = 1; PValue = 0.899; mean CPM = 0.8823; cadherin 1, type 1, E-cadherin (epithelial)" ID="ID_197164724" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FZD3: 1.03-fold Up; FDR = 1; PValue = 0.903; mean CPM = 1.636; frizzled homolog 3 (Drosophila)" ID="ID_268393828" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOX10: 1.09-fold Up; FDR = 1; PValue = 0.973; mean CPM = 0.8642; SRY (sex determining region Y)-box 10" ID="ID_953072036" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LHX1: 1.01-fold Down; FDR = 1; PValue = 0.99; mean CPM = 0.7995; LIM homeobox 1" ID="ID_1934117128" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PAX3: 1.02-fold Down; FDR = 1; PValue = 0.992; mean CPM = 0.8512; paired box 3" ID="ID_593479395" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BMP7: 1.01-fold Up; FDR = 1; PValue = 0.994; mean CPM = 0.8010; bone morphogenetic protein 7" ID="ID_1900968812" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GJB1: No Change; FDR = 1; PValue = 1; mean CPM = 0.7851; gap junction protein, beta 1, 32kDa" ID="ID_341131373" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Cholesterol Biosynthesis (WP197:Rev44991): FDR = 2.65e-07, PValue = 6.07e-08" ID="ID_27830843" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="DHCR7: 3.58-fold Down; FDR = 6.01e-13; PValue = 9.35e-15; mean CPM = 15.72; 7-dehydrocholesterol reductase" ID="ID_1633431989" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MVD: 2.35-fold Down; FDR = 8.85e-13; PValue = 1.42e-14; mean CPM = 18.63; mevalonate (diphospho) decarboxylase" ID="ID_1847173552" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SREBF2: 2.26-fold Down; FDR = 4.11e-12; PValue = 7.71e-14; mean CPM = 92.78; sterol regulatory element binding transcription factor 2" ID="ID_1360424375" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SQLE: 2.41-fold Down; FDR = 1.15e-07; PValue = 6.53e-09; mean CPM = 13.58; squalene epoxidase" ID="ID_1840307833" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MVK: 1.96-fold Down; FDR = 9.13e-07; PValue = 6.52e-08; mean CPM = 6.973; mevalonate kinase" ID="ID_1029300662" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SC4MOL: 1.54-fold Down; FDR = 1.24e-05; PValue = 1.18e-06; mean CPM = 17.46; sterol-C4-methyl oxidase-like" ID="ID_125980976" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LSS: 1.52-fold Down; FDR = 1.4e-05; PValue = 1.36e-06; mean CPM = 23.62; lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)" ID="ID_1292017948" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PMVK: 1.42-fold Down; FDR = 0.000723; PValue = 0.000117; mean CPM = 36.39; phosphomevalonate kinase" ID="ID_418287238" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HMGCS1: 1.31-fold Down; FDR = 0.00578; PValue = 0.00125; mean CPM = 19.39; 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)" ID="ID_543083339" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HMGCR: 1.25-fold Down; FDR = 0.00707; PValue = 0.00157; mean CPM = 46.64; 3-hydroxy-3-methylglutaryl-CoA reductase" ID="ID_1725305010" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CYP51A1: 1.2-fold Down; FDR = 0.0512; PValue = 0.0158; mean CPM = 34.30; cytochrome P450, family 51, subfamily A, polypeptide 1" ID="ID_1625799963" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FDPS: 1.15-fold Down; FDR = 0.126; PValue = 0.0464; mean CPM = 49.16; farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)" ID="ID_903051633" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SC5DL: 1.17-fold Up; FDR = 0.197; PValue = 0.0805; mean CPM = 23.20; sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like" ID="ID_802457104" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SREBF1: 1.11-fold Down; FDR = 0.324; PValue = 0.149; mean CPM = 179.9; sterol regulatory element binding transcription factor 1" ID="ID_1909104505" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FDFT1: 1.12-fold Up; FDR = 0.359; PValue = 0.169; mean CPM = 22.76; farnesyl-diphosphate farnesyltransferase 1" ID="ID_589159496" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NSDHL: 1.11-fold Down; FDR = 0.362; PValue = 0.171; mean CPM = 34.39; NAD(P) dependent steroid dehydrogenase-like" ID="ID_1008830179" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IDI1: 1.1-fold Down; FDR = 0.525; PValue = 0.276; mean CPM = 20.34; isopentenyl-diphosphate delta isomerase 1" ID="ID_3314273" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Alpha 6 Beta 4 signaling pathway (WP244:Rev44947): FDR = 3.11e-07, PValue = 7.29e-08" ID="ID_659052967" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="LAMC1: 2.28-fold Down; FDR = 6.46e-13; PValue = 1.01e-14; mean CPM = 812.1; laminin, gamma 1 (formerly LAMB2)" ID="ID_1322575780" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016591: 4.2-fold Down; FDR = 1.3e-11; PValue = 2.78e-13; mean CPM = 34.90; Uncharacterized protein" ID="ID_1234793479" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000016587: 4.92-fold Down; FDR = 1.6e-11; PValue = 3.5e-13; mean CPM = 51.70; Uncharacterized protein" ID="ID_40908020" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IRS1: 2.78-fold Up; FDR = 7.67e-09; PValue = 3.19e-10; mean CPM = 26.55; Uncharacterized protein" ID="ID_1595670535" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_1576477974" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMC2: 2.28-fold Down; FDR = 9.83e-06; PValue = 9.24e-07; mean CPM = 16.99; laminin, gamma 2" ID="ID_384641699" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB2: 1.48-fold Down; FDR = 0.000398; PValue = 5.93e-05; mean CPM = 695.6; laminin, beta 2 (laminin S)" ID="ID_1604908650" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MTOR: 1.3-fold Down; FDR = 0.00117; PValue = 0.000201; mean CPM = 107.5; mechanistic target of rapamycin (serine/threonine kinase)" ID="ID_941149370" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RHOA: 1.28-fold Down; FDR = 0.00295; PValue = 0.000575; mean CPM = 277.8; ras homolog gene family, member A" ID="ID_581780861" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ITGB4: 1.66-fold Down; FDR = 0.00369; PValue = 0.000748; mean CPM = 5.291; integrin, beta 4" ID="ID_1022531144" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_760530791" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1223942433" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HRAS: 1.18-fold Down; FDR = 0.0703; PValue = 0.0231; mean CPM = 36.86; v-Ha-ras Harvey rat sarcoma viral oncogene homolog" ID="ID_1543667886" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EIF4EBP1: 1.23-fold Up; FDR = 0.0729; PValue = 0.0241; mean CPM = 40.55; eukaryotic translation initiation factor 4E binding protein 1" ID="ID_56732354" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_1879450798" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014969: 1.93-fold Down; FDR = 0.303; PValue = 0.137; mean CPM = 0.9384; Uncharacterized protein" ID="ID_1054903189" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LAMB3: 1.6-fold Down; FDR = 0.303; PValue = 0.137; mean CPM = 1.445; laminin, beta 3" ID="ID_1825389952" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2: 1.1-fold Up; FDR = 0.394; PValue = 0.191; mean CPM = 102.5; PTK2 protein tyrosine kinase 2" ID="ID_468811970" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_1018127940" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_210188971" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_1545783104" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GAB1: 1.1-fold Up; FDR = 0.635; PValue = 0.356; mean CPM = 14.59; GRB2-associated binding protein 1" ID="ID_1167125377" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCD: 1.06-fold Up; FDR = 0.696; PValue = 0.404; mean CPM = 37.45; protein kinase C, delta" ID="ID_956458853" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000014966: 1.43-fold Down; FDR = 0.72; PValue = 0.423; mean CPM = 0.9009; Uncharacterized protein" ID="ID_223360960" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_855340176" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="EGF/EGFR Signaling Pathway (WP437:Rev44600): FDR = 3.54e-07, PValue = 8.48e-08" ID="ID_833204608" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="PLSCR1: 7.98-fold Up; FDR = 1.36e-23; PValue = 1.85e-26; mean CPM = 67.08; phospholipid scramblase 1" ID="ID_1128017595" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK2: 3.64-fold Up; FDR = 1.88e-18; PValue = 1.01e-20; mean CPM = 56.10; Janus kinase 2" ID="ID_155007444" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT1: 7.26-fold Up; FDR = 2.16e-18; PValue = 1.2e-20; mean CPM = 2689; signal transducer and activator of transcription 1, 91kDa" ID="ID_1192793452" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5A: 2.28-fold Up; FDR = 6.87e-14; PValue = 8.58e-16; mean CPM = 21.55; signal transducer and activator of transcription 5A" ID="ID_1938931288" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="USP6NL: 1.99-fold Up; FDR = 1.08e-12; PValue = 1.76e-14; mean CPM = 24.20; USP6 N-terminal like" ID="ID_1232100637" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT3: 1.67-fold Up; FDR = 4.11e-11; PValue = 1e-12; mean CPM = 162.1; Uncharacterized protein" ID="ID_1873222159" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DNM1: 1.84-fold Down; FDR = 4.11e-11; PValue = 1.01e-12; mean CPM = 19.55; dynamin 1" ID="ID_199179903" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EPS15: 1.66-fold Up; FDR = 1.92e-10; PValue = 5.44e-12; mean CPM = 91.05; epidermal growth factor receptor pathway substrate 15" ID="ID_1536552303" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIAS3: 1.63-fold Down; FDR = 2.24e-10; PValue = 6.51e-12; mean CPM = 53.00; protein inhibitor of activated STAT, 3" ID="ID_519032198" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS1: 1.69-fold Up; FDR = 4.45e-09; PValue = 1.77e-10; mean CPM = 47.70; son of sevenless homolog 1 (Drosophila)" ID="ID_1182784915" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGFR: 1.84-fold Up; FDR = 6.71e-09; PValue = 2.77e-10; mean CPM = 68.58; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)" ID="ID_1834259455" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2B: 3.54-fold Up; FDR = 1.24e-07; PValue = 7.07e-09; mean CPM = 5.971; PTK2B protein tyrosine kinase 2 beta" ID="ID_451226824" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RALGDS: 2.6-fold Up; FDR = 2.12e-07; PValue = 1.28e-08; mean CPM = 47.88; ral guanine nucleotide dissociation stimulator" ID="ID_653309620" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EPS8: 1.49-fold Up; FDR = 3.46e-07; PValue = 2.2e-08; mean CPM = 136.8; Uncharacterized protein" ID="ID_1393150870" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3R2: 1.53-fold Down; FDR = 4.32e-07; PValue = 2.82e-08; mean CPM = 31.53; Phosphatidylinositol 3-kinase regulatory subunit beta; Uncharacterized protein" ID="ID_663216360" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK8: 1.51-fold Up; FDR = 2.32e-06; PValue = 1.83e-07; mean CPM = 26.28; mitogen-activated protein kinase 8" ID="ID_1225098481" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAT5B: 1.44-fold Up; FDR = 3.04e-06; PValue = 2.47e-07; mean CPM = 68.58; signal transducer and activator of transcription 5B" ID="ID_728683303" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATF1: 1.51-fold Up; FDR = 5.28e-06; PValue = 4.58e-07; mean CPM = 22.13; activating transcription factor 1" ID="ID_259399430" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA5: 3.28-fold Up; FDR = 1.4e-05; PValue = 1.36e-06; mean CPM = 2.288; ribosomal protein S6 kinase, 90kDa, polypeptide 5" ID="ID_1296024189" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_1983156949" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNK2: 1.75-fold Down; FDR = 3.26e-05; PValue = 3.5e-06; mean CPM = 44.07; tyrosine kinase, non-receptor, 2" ID="ID_676122907" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN12: 1.38-fold Up; FDR = 5.72e-05; PValue = 6.61e-06; mean CPM = 113.6; protein tyrosine phosphatase, non-receptor type 12" ID="ID_197496110" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCE1: 3.26-fold Down; FDR = 6.36e-05; PValue = 7.45e-06; mean CPM = 11.49; phospholipase C, epsilon 1" ID="ID_843624494" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K5: 1.55-fold Up; FDR = 7.6e-05; PValue = 9.12e-06; mean CPM = 16.82; mitogen-activated protein kinase kinase 5" ID="ID_959341248" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GJA1: 1.71-fold Up; FDR = 0.000117; PValue = 1.47e-05; mean CPM = 2600; gap junction protein, alpha 1, 43kDa" ID="ID_896615903" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BCAR1: 1.36-fold Up; FDR = 0.000193; PValue = 2.61e-05; mean CPM = 210.4; breast cancer anti-estrogen resistance 1" ID="ID_1961608733" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K1: 1.47-fold Up; FDR = 0.000434; PValue = 6.54e-05; mean CPM = 12.97; mitogen-activated protein kinase kinase kinase 1" ID="ID_250070674" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCK1: 1.39-fold Up; FDR = 0.000442; PValue = 6.67e-05; mean CPM = 21.55; NCK adaptor protein 1" ID="ID_21267251" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ELK4: 1.37-fold Up; FDR = 0.000508; PValue = 7.78e-05; mean CPM = 24.59; ELK4, ETS-domain protein (SRF accessory protein 1)" ID="ID_1012766879" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EPN1: 1.32-fold Down; FDR = 0.000578; PValue = 9.03e-05; mean CPM = 187.8; epsin 1" ID="ID_1241586013" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IQSEC1: 1.35-fold Down; FDR = 0.000605; PValue = 9.51e-05; mean CPM = 42.81; Uncharacterized protein" ID="ID_421580490" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOSB: 2.11-fold Down; FDR = 0.000873; PValue = 0.000145; mean CPM = 81.52; FBJ murine osteosarcoma viral oncogene homolog B" ID="ID_790932437" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOXO1: 1.49-fold Down; FDR = 0.00109; PValue = 0.000186; mean CPM = 11.95; forkhead box O1" ID="ID_1248940037" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAMK2A: 2.29-fold Down; FDR = 0.00124; PValue = 0.000217; mean CPM = 2.001; calcium/calmodulin-dependent protein kinase II alpha" ID="ID_1744965609" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAM2: 1.3-fold Up; FDR = 0.00163; PValue = 0.000295; mean CPM = 50.32; signal transducing adaptor molecule (SH3 domain and ITAM motif) 2" ID="ID_1746495986" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYBL2: 2.12-fold Down; FDR = 0.00174; PValue = 0.000316; mean CPM = 19.60; v-myb avian myeloblastosis viral oncogene homolog-like 2" ID="ID_1748150518" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GAB2: 1.33-fold Down; FDR = 0.00208; PValue = 0.000387; mean CPM = 22.59; GRB2-associated binding protein 2" ID="ID_654923771" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARHGEF1: 1.3-fold Down; FDR = 0.00297; PValue = 0.000581; mean CPM = 51.91; Rho guanine nucleotide exchange factor (GEF) 1" ID="ID_413428683" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RALA: 1.28-fold Up; FDR = 0.00322; PValue = 0.000638; mean CPM = 42.83; v-ral simian leukemia viral oncogene homolog A (ras related)" ID="ID_1348878772" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLCG1: 1.31-fold Down; FDR = 0.00352; PValue = 0.000707; mean CPM = 53.66; phospholipase C, gamma 1" ID="ID_530658752" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PCNA: 1.34-fold Up; FDR = 0.00398; PValue = 0.000816; mean CPM = 112.1; PCNA antisense RNA (non-protein coding)" ID="ID_298754447" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CBLC: 2.87-fold Down; FDR = 0.00443; PValue = 0.000923; mean CPM = 3.105; Cas-Br-M (murine) ecotropic retroviral transforming sequence c" ID="ID_500057943" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV3: 1.82-fold Down; FDR = 0.00463; PValue = 0.000973; mean CPM = 7.044; vav 3 guanine nucleotide exchange factor" ID="ID_1632202742" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LIMK2: 1.51-fold Down; FDR = 0.00509; PValue = 0.00108; mean CPM = 60.03; LIM domain kinase 2" ID="ID_1866862332" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="USP8: 1.26-fold Up; FDR = 0.00573; PValue = 0.00124; mean CPM = 83.83; ubiquitin specific peptidase 8" ID="ID_471572208" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAV1: 1.33-fold Down; FDR = 0.00575; PValue = 0.00125; mean CPM = 228.7; caveolin-1" ID="ID_1860857779" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K3: 1.26-fold Down; FDR = 0.00786; PValue = 0.00178; mean CPM = 38.85; mitogen-activated protein kinase kinase kinase 3" ID="ID_1365256318" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AP2B1: 1.25-fold Up; FDR = 0.00795; PValue = 0.0018; mean CPM = 199.8; adaptor-related protein complex 2, beta 1 subunit" ID="ID_1457557" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAB5A: 1.27-fold Up; FDR = 0.00988; PValue = 0.00232; mean CPM = 24.19; Uncharacterized protein" ID="ID_75696359" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ARF6: 1.24-fold Down; FDR = 0.0106; PValue = 0.00251; mean CPM = 87.11; ADP-ribosylation factor 6" ID="ID_1494491261" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SP1: 1.23-fold Up; FDR = 0.0139; PValue = 0.00344; mean CPM = 75.49; Transcription factor Sp1 isoform a; Uncharacterized protein" ID="ID_852711568" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NCK2: 1.25-fold Down; FDR = 0.0145; PValue = 0.0036; mean CPM = 30.56; Uncharacterized protein" ID="ID_813812132" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCZ: 1.51-fold Up; FDR = 0.0152; PValue = 0.00381; mean CPM = 10.46; protein kinase C, zeta" ID="ID_1829577141" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN5: 3.05-fold Down; FDR = 0.0177; PValue = 0.00455; mean CPM = 1.043; protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)" ID="ID_1161362577" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_616650613" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DOK2: 1.76-fold Down; FDR = 0.0214; PValue = 0.00569; mean CPM = 2.236; docking protein 2, 56kDa" ID="ID_182042178" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA1: 1.25-fold Down; FDR = 0.0241; PValue = 0.00652; mean CPM = 21.28; ribosomal protein S6 kinase, 90kDa, polypeptide 1" ID="ID_64547265" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AKT1: 1.21-fold Down; FDR = 0.0257; PValue = 0.00703; mean CPM = 165.7; v-akt murine thymoma viral oncogene homolog 1" ID="ID_1411062053" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INPP5D: 1.88-fold Down; FDR = 0.0276; PValue = 0.00763; mean CPM = 5.690; inositol polyphosphate-5-phosphatase, 145kDa" ID="ID_11615355" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOS: 1.51-fold Down; FDR = 0.0297; PValue = 0.00832; mean CPM = 329.9; FBJ murine osteosarcoma viral oncogene homolog" ID="ID_473971380" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB1: 1.21-fold Up; FDR = 0.0313; PValue = 0.00884; mean CPM = 36.07; cAMP responsive element binding protein 1" ID="ID_215515124" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDPK1: 1.24-fold Down; FDR = 0.0361; PValue = 0.0105; mean CPM = 17.53; 3-phosphoinositide dependent protein kinase-1" ID="ID_1874335389" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SYNJ1: 1.25-fold Down; FDR = 0.0395; PValue = 0.0117; mean CPM = 23.44; synaptojanin 1" ID="ID_1117305444" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="INPPL1: 1.2-fold Down; FDR = 0.0395; PValue = 0.0117; mean CPM = 129.4; Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2; Uncharacterized protein" ID="ID_1595188981" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KRAS: 1.35-fold Down; FDR = 0.0401; PValue = 0.0119; mean CPM = 13.10; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog" ID="ID_1260618862" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FOXO4: 1.28-fold Down; FDR = 0.0401; PValue = 0.0119; mean CPM = 12.01; forkhead box O4" ID="ID_474234156" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="E2F1: 1.44-fold Down; FDR = 0.0425; PValue = 0.0127; mean CPM = 8.857; E2F transcription factor 1" ID="ID_1966825632" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAMBP: 1.18-fold Up; FDR = 0.0641; PValue = 0.0207; mean CPM = 43.16; STAM binding protein" ID="ID_414373365" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STXBP1: 1.22-fold Up; FDR = 0.0669; PValue = 0.0217; mean CPM = 53.70; syntaxin binding protein 1" ID="ID_1518384568" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAB5A: 1.17-fold Up; FDR = 0.0885; PValue = 0.0303; mean CPM = 164.1; RAB5A, member RAS oncogene family" ID="ID_211173875" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAP1A: 1.17-fold Up; FDR = 0.0888; PValue = 0.0304; mean CPM = 37.16; RAP1A, member of RAS oncogene family" ID="ID_410248095" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JAK1: 1.17-fold Up; FDR = 0.0944; PValue = 0.0327; mean CPM = 243.5; Tyrosine-protein kinase" ID="ID_62378431" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SOS2: 1.17-fold Up; FDR = 0.1; PValue = 0.0353; mean CPM = 31.79; son of sevenless homolog 2 (Drosophila)" ID="ID_57224922" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NEDD8: 1.16-fold Up; FDR = 0.107; PValue = 0.0381; mean CPM = 112.7; neural precursor cell expressed, developmentally down-regulated 8" ID="ID_442645880" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="REPS2: 1.42-fold Down; FDR = 0.114; PValue = 0.0411; mean CPM = 3.004; RALBP1 associated Eps domain containing 2" ID="ID_1170443260" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RIN1: 1.21-fold Up; FDR = 0.121; PValue = 0.0441; mean CPM = 49.27; Ras and Rab interactor 1" ID="ID_424644609" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK9: 1.17-fold Up; FDR = 0.128; PValue = 0.0473; mean CPM = 21.94; mitogen-activated protein kinase 9" ID="ID_162305266" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="JUN: 1.21-fold Down; FDR = 0.148; PValue = 0.0565; mean CPM = 143.4; jun oncogene" ID="ID_730948307" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PLD1: 1.24-fold Down; FDR = 0.162; PValue = 0.0634; mean CPM = 15.80; phospholipase D1, phosphatidylcholine-specific" ID="ID_134111300" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTEN: 1.14-fold Up; FDR = 0.166; PValue = 0.065; mean CPM = 89.60; phosphatase and tensin homolog" ID="ID_168066230" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRB2: 1.13-fold Up; FDR = 0.197; PValue = 0.0808; mean CPM = 46.42; growth factor receptor-bound protein 2" ID="ID_1419360634" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AP2S1: 1.13-fold Down; FDR = 0.213; PValue = 0.0887; mean CPM = 107.4; adaptor-related protein complex 2, sigma 1 subunit" ID="ID_35948648" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SHC1: 1.13-fold Up; FDR = 0.217; PValue = 0.0907; mean CPM = 586.4; SHC (Src homology 2 domain containing) transforming protein 1" ID="ID_1318028408" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="BRAF: 1.14-fold Down; FDR = 0.228; PValue = 0.0964; mean CPM = 24.98; v-raf murine sarcoma viral oncogene homolog B1" ID="ID_1502972409" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ERBB2: 1.14-fold Down; FDR = 0.23; PValue = 0.0977; mean CPM = 119.0; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)" ID="ID_1384785387" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TWIST1: 1.18-fold Up; FDR = 0.24; PValue = 0.103; mean CPM = 10.19; Twist-like protein; Uncharacterized protein" ID="ID_1853746517" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ERRFI1: 1.18-fold Up; FDR = 0.249; PValue = 0.108; mean CPM = 667.2; ERBB receptor feedback inhibitor 1" ID="ID_1234577355" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K4: 1.13-fold Down; FDR = 0.284; PValue = 0.126; mean CPM = 25.34; Uncharacterized protein" ID="ID_1942525750" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ATXN2: 1.11-fold Down; FDR = 0.324; PValue = 0.149; mean CPM = 54.19; ataxin 2" ID="ID_1897868508" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRKL: 1.11-fold Up; FDR = 0.371; PValue = 0.176; mean CPM = 34.10; v-crk sarcoma virus CT10 oncogene homolog (avian)-like" ID="ID_1728398463" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SH3KBP1: 1.11-fold Up; FDR = 0.393; PValue = 0.19; mean CPM = 22.80; SH3-domain kinase binding protein 1" ID="ID_334913733" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK2: 1.1-fold Up; FDR = 0.394; PValue = 0.191; mean CPM = 102.5; PTK2 protein tyrosine kinase 2" ID="ID_1685925987" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PIK3C2B: 1.17-fold Down; FDR = 0.406; PValue = 0.198; mean CPM = 6.381; phosphoinositide-3-kinase, class 2, beta polypeptide" ID="ID_811301467" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK14: 1.09-fold Up; FDR = 0.421; PValue = 0.207; mean CPM = 52.01; mitogen-activated protein kinase 14" ID="ID_760675037" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ABL1: 1.09-fold Up; FDR = 0.43; PValue = 0.213; mean CPM = 178.0; c-abl oncogene 1, receptor tyrosine kinase" ID="ID_1111142886" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTPN11: 1.19-fold Down; FDR = 0.45; PValue = 0.225; mean CPM = 4.077; protein tyrosine phosphatase, non-receptor type 11" ID="ID_1030534109" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="HGS: 1.09-fold Down; FDR = 0.453; PValue = 0.227; mean CPM = 129.1; hepatocyte growth factor-regulated tyrosine kinase substrate" ID="ID_1208142291" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SPRY2: 1.09-fold Down; FDR = 0.515; PValue = 0.269; mean CPM = 27.90; sprouty homolog 2 (Drosophila)" ID="ID_1956273258" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCI: 1.08-fold Up; FDR = 0.518; PValue = 0.271; mean CPM = 47.99; protein kinase C, iota" ID="ID_1164058136" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CDC42: 1.07-fold Down; FDR = 0.608; PValue = 0.335; mean CPM = 91.67; cell division cycle 42" ID="ID_198560716" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GAB1: 1.1-fold Up; FDR = 0.635; PValue = 0.356; mean CPM = 14.59; GRB2-associated binding protein 1" ID="ID_383216005" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CSK: 1.06-fold Down; FDR = 0.673; PValue = 0.386; mean CPM = 45.36; c-src tyrosine kinase" ID="ID_913589657" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STMN1: 1.15-fold Down; FDR = 0.684; PValue = 0.395; mean CPM = 43.13; Stathmin" ID="ID_1287445445" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCD: 1.06-fold Up; FDR = 0.696; PValue = 0.404; mean CPM = 37.45; protein kinase C, delta" ID="ID_677045441" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SH3GL2: 2.1-fold Down; FDR = 0.726; PValue = 0.428; mean CPM = 0.8623; SH3-domain GRB2-like 2" ID="ID_246155791" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCB: 1.86-fold Up; FDR = 0.727; PValue = 0.43; mean CPM = 0.8705; protein kinase C, beta" ID="ID_411128898" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="AURKA: 1.12-fold Down; FDR = 0.746; PValue = 0.446; mean CPM = 12.28; aurora kinase A" ID="ID_1190810244" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CRK: 1.05-fold Up; FDR = 0.791; PValue = 0.488; mean CPM = 59.92; v-crk sarcoma virus CT10 oncogene homolog (avian)" ID="ID_312513800" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV1: 1.25-fold Down; FDR = 0.858; PValue = 0.572; mean CPM = 0.9515; vav 1 guanine nucleotide exchange factor" ID="ID_1586559913" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1425267200" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP4K1: 1.26-fold Up; FDR = 0.879; PValue = 0.598; mean CPM = 0.9281; mitogen-activated protein kinase kinase kinase kinase 1" ID="ID_901762814" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KB1: 1.04-fold Up; FDR = 0.88; PValue = 0.6; mean CPM = 30.80; Uncharacterized protein" ID="ID_968791357" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PEBP1: 1.07-fold Up; FDR = 0.886; PValue = 0.607; mean CPM = 5.026; phosphatidylethanolamine binding protein 1" ID="ID_1098579517" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="STAM: 1.04-fold Down; FDR = 0.899; PValue = 0.627; mean CPM = 29.84; signal transducing adaptor molecule (SH3 domain and ITAM motif) 1" ID="ID_34626190" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK7: 1.04-fold Down; FDR = 0.899; PValue = 0.632; mean CPM = 16.93; Uncharacterized protein" ID="ID_1314878697" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RASA1: 1.03-fold Down; FDR = 0.909; PValue = 0.69; mean CPM = 103.7; Ras GTPase-activating protein 1 isoform 1; Uncharacterized protein" ID="ID_1865495284" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="LIMK2: 1.14-fold Down; FDR = 0.911; PValue = 0.697; mean CPM = 0.7896; LIM domain kinase 2" ID="ID_579732002" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IQGAP1: 1.03-fold Down; FDR = 0.911; PValue = 0.7; mean CPM = 702.2; IQ motif containing GTPase activating protein 1" ID="ID_1877791815" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP3K2: 1.03-fold Up; FDR = 0.924; PValue = 0.73; mean CPM = 40.64; mitogen-activated protein kinase kinase kinase 2" ID="ID_735878946" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012063: 1.28-fold Down; FDR = 0.945; PValue = 0.766; mean CPM = 0.8306; Uncharacterized protein" ID="ID_288538553" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SH3GL3: 1.1-fold Up; FDR = 0.962; PValue = 0.796; mean CPM = 0.9593; Uncharacterized protein" ID="ID_707952488" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RAC1: 1.02-fold Down; FDR = 0.967; PValue = 0.805; mean CPM = 28.82; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" ID="ID_540164149" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RPS6KA3: 1.02-fold Up; FDR = 0.982; PValue = 0.829; mean CPM = 58.16; ribosomal protein S6 kinase, 90kDa, polypeptide 3" ID="ID_1788939531" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NDUFA13: 1.01-fold Down; FDR = 1; PValue = 0.872; mean CPM = 278.5; Uncharacterized protein" ID="ID_1188811360" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="EGF: 1.06-fold Down; FDR = 1; PValue = 0.885; mean CPM = 0.8917; epidermal growth factor" ID="ID_483837677" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="RALBP1: 1.01-fold Up; FDR = 1; PValue = 0.943; mean CPM = 72.93; Uncharacterized protein" ID="ID_1031868557" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK4: 1.19-fold Down; FDR = 1; PValue = 0.95; mean CPM = 0.8611; mitogen-activated protein kinase 4" ID="ID_612628169" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VAV2: No Change; FDR = 1; PValue = 0.976; mean CPM = 25.65; vav 2 guanine nucleotide exchange factor" ID="ID_1964609561" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SH2D2A: No Change; FDR = 1; PValue = 0.997; mean CPM = 1.375; SH2 domain containing 2A" ID="ID_462055490" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PTK6: 1.04-fold Up; FDR = 1; PValue = 1; mean CPM = 0.8141; PTK6 protein tyrosine kinase 6" ID="ID_1345918145" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Hypothetical Network for Drug Addiction (WP666:Rev45365): FDR = 5.54e-07, PValue = 1.36e-07" ID="ID_1002700101" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="GRIA1: 7.88-fold Down; FDR = 3.44e-12; PValue = 6.37e-14; mean CPM = 5.809; glutamate receptor, ionotropic, AMPA 1" ID="ID_1392634869" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPA1: 2.1-fold Up; FDR = 1.04e-11; PValue = 2.17e-13; mean CPM = 69.99; Uncharacterized protein" ID="ID_335501074" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K1: 1.41-fold Up; FDR = 1.41e-05; PValue = 1.37e-06; mean CPM = 103.2; mitogen-activated protein kinase kinase 1" ID="ID_436434654" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="NISCH: 1.41-fold Down; FDR = 0.000122; PValue = 1.55e-05; mean CPM = 78.46; nischarin" ID="ID_1814662499" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKCE: 1.73-fold Up; FDR = 0.00013; PValue = 1.67e-05; mean CPM = 10.87; protein kinase C, epsilon" ID="ID_456872339" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PRKACA: 1.36-fold Down; FDR = 0.000167; PValue = 2.22e-05; mean CPM = 37.75; protein kinase, cAMP-dependent, catalytic, alpha" ID="ID_439340094" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACTA1: 5.36-fold Down; FDR = 0.000251; PValue = 3.52e-05; mean CPM = 5.880; Uncharacterized protein" ID="ID_1482442352" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRIN2C: 1.94-fold Down; FDR = 0.00298; PValue = 0.000582; mean CPM = 2.673; glutamate receptor, ionotropic, N-methyl D-aspartate 2C" ID="ID_1568765242" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRIN2D: 2.02-fold Down; FDR = 0.00378; PValue = 0.00077; mean CPM = 3.190; glutamate receptor, ionotropic, N-methyl D-aspartate 2D" ID="ID_1629453878" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAMK2B: 3.82-fold Down; FDR = 0.00536; PValue = 0.00115; mean CPM = 1.542; calcium/calmodulin-dependent protein kinase II beta" ID="ID_658117098" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PPA1: 2.24-fold Up; FDR = 0.00738; PValue = 0.00165; mean CPM = 1.897; pyrophosphatase (inorganic) 1" ID="ID_1041795129" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK1: 1.22-fold Up; FDR = 0.0198; PValue = 0.00522; mean CPM = 56.44; mitogen-activated protein kinase 1" ID="ID_813452160" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="KRIT1: 1.23-fold Up; FDR = 0.0264; PValue = 0.00726; mean CPM = 32.04; KRIT1, ankyrin repeat containing" ID="ID_219451778" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRIN2B: 3.63-fold Down; FDR = 0.0282; PValue = 0.00782; mean CPM = 1.577; glutamate receptor, ionotropic, N-methyl D-aspartate 2B" ID="ID_1204534961" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CREB1: 1.21-fold Up; FDR = 0.0313; PValue = 0.00884; mean CPM = 36.07; cAMP responsive element binding protein 1" ID="ID_330935045" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TERF2IP: 1.15-fold Down; FDR = 0.12; PValue = 0.0439; mean CPM = 46.09; telomeric repeat binding factor 2, interacting protein" ID="ID_27537363" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRIN2A: 1.69-fold Down; FDR = 0.433; PValue = 0.214; mean CPM = 0.9509; glutamate receptor, ionotropic, N-methyl D-aspartate 2A" ID="ID_1724920312" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAPK3: 1.09-fold Up; FDR = 0.45; PValue = 0.225; mean CPM = 65.52; mitogen-activated protein kinase 3" ID="ID_168590246" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GJB7: 1.38-fold Up; FDR = 0.651; PValue = 0.369; mean CPM = 1.104; gap junction protein, beta 7, 25kDa" ID="ID_1698443322" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CAMK4: 1.9-fold Up; FDR = 0.66; PValue = 0.375; mean CPM = 0.8628; calcium/calmodulin-dependent protein kinase IV" ID="ID_1890030186" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRM5: 1.51-fold Up; FDR = 0.665; PValue = 0.38; mean CPM = 0.9962; glutamate receptor, metabotropic 5" ID="ID_825550722" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRIA3: 1.17-fold Down; FDR = 0.725; PValue = 0.427; mean CPM = 3.864; glutamate receptor, ionotrophic, AMPA 3" ID="ID_629272597" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DRD1: 1.79-fold Up; FDR = 0.736; PValue = 0.438; mean CPM = 0.8307; dopamine receptor D1" ID="ID_28718933" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRM1: 1.8-fold Down; FDR = 0.771; PValue = 0.469; mean CPM = 0.8322; glutamate receptor, metabotropic 1" ID="ID_204559191" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MAP2K2: 1.04-fold Down; FDR = 0.877; PValue = 0.596; mean CPM = 274.1; mitogen-activated protein kinase kinase 2" ID="ID_1623279609" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY8: 1.28-fold Up; FDR = 0.891; PValue = 0.614; mean CPM = 0.8757; adenylate cyclase 8 (brain)" ID="ID_274269770" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRIN1: 1.44-fold Up; FDR = 0.903; PValue = 0.646; mean CPM = 0.8658; glutamate receptor, ionotropic, N-methyl D-aspartate 1" ID="ID_112995012" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ZHX2: 1.04-fold Down; FDR = 0.903; PValue = 0.659; mean CPM = 17.70; zinc fingers and homeoboxes 2" ID="ID_265640937" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ADCY1: 1.13-fold Down; FDR = 0.908; PValue = 0.682; mean CPM = 1.243; adenylate cyclase 1 (brain)" ID="ID_1280728207" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GRIA4: 1.39-fold Down; FDR = 0.999; PValue = 0.857; mean CPM = 0.8683; glutamate receptor, ionotrophic, AMPA 4" ID="ID_1037021216" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Glutathione metabolism (WP100:Rev45319): FDR = 7.22e-07, PValue = 1.81e-07" ID="ID_927221737" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="OPLAH: 4.24-fold Down; FDR = 4.67e-14; PValue = 5.59e-16; mean CPM = 15.18; 5-oxoprolinase (ATP-hydrolysing)" ID="ID_1306089448" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GCLM: 1.99-fold Up; FDR = 8.02e-08; PValue = 4.38e-09; mean CPM = 17.26; glutamate-cysteine ligase, modifier subunit" ID="ID_1596693920" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IDH1: 1.87-fold Up; FDR = 1.39e-07; PValue = 8.02e-09; mean CPM = 56.62; isocitrate dehydrogenase 1 (NADP+), soluble" ID="ID_1622077882" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ANPEP: 2.06-fold Down; FDR = 0.000149; PValue = 1.95e-05; mean CPM = 9.629; alanyl (membrane) aminopeptidase" ID="ID_1403467334" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GGT5: 1.54-fold Up; FDR = 0.00581; PValue = 0.00126; mean CPM = 42.83; gamma-glutamyltransferase 5" ID="ID_1505695600" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GGT5: 1.49-fold Up; FDR = 0.0151; PValue = 0.00378; mean CPM = 6.923; gamma-glutamyltransferase 5" ID="ID_1417380686" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSTT2B: 1.27-fold Up; FDR = 0.0194; PValue = 0.00509; mean CPM = 16.85; glutathione S-transferase theta 2B (gene/pseudogene)" ID="ID_1729233968" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSR: 1.26-fold Up; FDR = 0.0263; PValue = 0.00721; mean CPM = 28.15; glutathione reductase" ID="ID_755128239" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSS: 1.19-fold Down; FDR = 0.0461; PValue = 0.014; mean CPM = 57.28; glutathione synthetase" ID="ID_1651358622" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSTM1: 1.17-fold Down; FDR = 0.199; PValue = 0.0815; mean CPM = 19.09; glutathione S-transferase mu 1" ID="ID_837043686" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GCLC: 1.1-fold Up; FDR = 0.649; PValue = 0.367; mean CPM = 261.3; glutamate-cysteine ligase, catalytic subunit" ID="ID_1489521483" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSTA1: 1.14-fold Down; FDR = 0.911; PValue = 0.697; mean CPM = 0.7880; glutathione S-transferase alpha 1" ID="ID_724206722" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="GSTT1: 1.04-fold Down; FDR = 1; PValue = 0.861; mean CPM = 2.560; glutathione S-transferase theta 1" ID="ID_699974612" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="Striated Muscle Contraction (WP383:Rev45112): FDR = 7.58e-07, PValue = 1.93e-07" ID="ID_1846608481" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="MYOM1: 6.65-fold Down; FDR = 1.7e-13; PValue = 2.34e-15; mean CPM = 107.5; myomesin 1" ID="ID_671001821" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DMD: 2.29-fold Down; FDR = 6.37e-12; PValue = 1.28e-13; mean CPM = 17.66; Uncharacterized protein" ID="ID_1547245813" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYH3: 3.39-fold Down; FDR = 5.36e-09; PValue = 2.17e-10; mean CPM = 6.410; myosin, heavy chain 3, skeletal muscle, embryonic" ID="ID_1090413994" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TPM4: 1.8-fold Down; FDR = 1.34e-08; PValue = 5.96e-10; mean CPM = 1400; tropomyosin 4" ID="ID_1029751739" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYL9: 2.18-fold Down; FDR = 2.17e-08; PValue = 1.03e-09; mean CPM = 805.4; myosin, light chain 9, regulatory" ID="ID_1022576008" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACTN4: 1.63-fold Down; FDR = 6.46e-08; PValue = 3.46e-09; mean CPM = 631.8; actinin, alpha 4" ID="ID_881015153" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DES: 9.53-fold Up; FDR = 7.57e-08; PValue = 4.1e-09; mean CPM = 59.19; desmin" ID="ID_1401297965" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYH8: 4.72-fold Down; FDR = 3.49e-06; PValue = 2.9e-07; mean CPM = 5.170; myosin, heavy chain 8, skeletal muscle, perinatal" ID="ID_288360537" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYBPC3: 2.7-fold Down; FDR = 6.28e-06; PValue = 5.59e-07; mean CPM = 6.622; myosin binding protein C, cardiac" ID="ID_806925465" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TTN: 2.84-fold Down; FDR = 6.47e-06; PValue = 5.78e-07; mean CPM = 360.1; titin" ID="ID_1061676389" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TMOD1: 3.73-fold Down; FDR = 6.41e-05; PValue = 7.52e-06; mean CPM = 1.614; tropomodulin 1" ID="ID_1028289822" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="VIM: 1.54-fold Down; FDR = 0.000219; PValue = 3.01e-05; mean CPM = 3996; vimentin" ID="ID_1831188246" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACTA1: 5.36-fold Down; FDR = 0.000251; PValue = 3.52e-05; mean CPM = 5.880; Uncharacterized protein" ID="ID_895984919" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TCAP: 1.74-fold Down; FDR = 0.00819; PValue = 0.00187; mean CPM = 2.747; titin-cap (telethonin)" ID="ID_1692232622" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNNT1: 1.52-fold Up; FDR = 0.00827; PValue = 0.00189; mean CPM = 12.30; troponin T type 1 (skeletal, slow)" ID="ID_1449544269" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNNI3: 1.94-fold Up; FDR = 0.0102; PValue = 0.0024; mean CPM = 2.886; Uncharacterized protein" ID="ID_130846099" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACTC1: 2.5-fold Down; FDR = 0.0968; PValue = 0.0338; mean CPM = 0.9546; actin, alpha, cardiac muscle 1" ID="ID_1408524396" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYBPC2: 2.05-fold Down; FDR = 0.115; PValue = 0.0414; mean CPM = 1.104; myosin binding protein C, fast type" ID="ID_1510445962" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNNC2: 1.59-fold Down; FDR = 0.175; PValue = 0.0696; mean CPM = 1.542; troponin C type 2 (fast)" ID="ID_1568303327" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNNT2: 1.64-fold Down; FDR = 0.24; PValue = 0.103; mean CPM = 1.443; troponin T type 2 (cardiac)" ID="ID_1388786940" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNNT3: 1.62-fold Down; FDR = 0.242; PValue = 0.104; mean CPM = 1.547; troponin T type 3 (skeletal, fast)" ID="ID_873169353" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYL3: 2-fold Down; FDR = 0.263; PValue = 0.115; mean CPM = 1.026; myosin, light chain 3, alkali; ventricular, skeletal, slow" ID="ID_1531798530" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TPM2: 1.85-fold Down; FDR = 0.59; PValue = 0.322; mean CPM = 0.8275; tropomyosin 2 (beta)" ID="ID_834746579" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYL4: 1.32-fold Down; FDR = 0.787; PValue = 0.484; mean CPM = 0.9677; myosin, light chain 4, alkali; atrial, embryonic" ID="ID_457029538" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ACTN2: 1.69-fold Down; FDR = 0.791; PValue = 0.488; mean CPM = 0.8357; actinin, alpha 2" ID="ID_474915731" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYL1: 1.65-fold Down; FDR = 0.81; PValue = 0.507; mean CPM = 0.8220; myosin, light chain 1, alkali; skeletal, fast" ID="ID_1176337283" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNNI2: 1.43-fold Down; FDR = 0.835; PValue = 0.538; mean CPM = 0.8240; Troponin I, fast-twitch isoform; Uncharacterized protein" ID="ID_1688717510" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYL2: 1.15-fold Up; FDR = 0.909; PValue = 0.69; mean CPM = 0.7911; myosin, light chain 2, regulatory, cardiac, slow" ID="ID_290827629" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MYH6: 1.11-fold Up; FDR = 0.975; PValue = 0.817; mean CPM = 1.001; myosin, heavy chain 6, cardiac muscle, alpha" ID="ID_441901012" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="TNNC1: 1.03-fold Up; FDR = 1; PValue = 0.898; mean CPM = 11.38; troponin C type 1 (slow)" ID="ID_1303457344" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- <node TEXT="TCA Cycle (WP78:Rev45096): FDR = 7.91e-07, PValue = 2.06e-07" ID="ID_1477586665" CREATED="1400535622212" MODIFIED="1400535622212">
- <node TEXT="PC: 2.94-fold Down; FDR = 2.05e-12; PValue = 3.55e-14; mean CPM = 48.99; pyruvate carboxylase" ID="ID_888305623" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="FH: 2.1-fold Down; FDR = 2.26e-11; PValue = 5.1e-13; mean CPM = 160.6; fumarate hydratase" ID="ID_611399184" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="MDH2: 1.39-fold Down; FDR = 3.22e-05; PValue = 3.44e-06; mean CPM = 112.2; malate dehydrogenase 2, NAD (mitochondrial)" ID="ID_106493731" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDP2: 1.57-fold Down; FDR = 5.23e-05; PValue = 5.98e-06; mean CPM = 11.10; pyruvate dehyrogenase phosphatase catalytic subunit 2" ID="ID_37259070" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="CS: 1.34-fold Down; FDR = 0.000251; PValue = 3.53e-05; mean CPM = 99.88; citrate synthase" ID="ID_557828080" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDHB: 1.28-fold Down; FDR = 0.00241; PValue = 0.000459; mean CPM = 56.68; pyruvate dehydrogenase (lipoamide) beta" ID="ID_199639102" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDK4: 2.08-fold Up; FDR = 0.00288; PValue = 0.000559; mean CPM = 3.212; pyruvate dehydrogenase kinase, isozyme 4" ID="ID_701366333" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SUCLG2: 1.31-fold Up; FDR = 0.00642; PValue = 0.00141; mean CPM = 21.03; succinate-CoA ligase, GDP-forming, beta subunit" ID="ID_566674411" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DLST: 1.24-fold Down; FDR = 0.0107; PValue = 0.00254; mean CPM = 84.79; Uncharacterized protein" ID="ID_440883854" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SUCLA2: 1.23-fold Up; FDR = 0.0178; PValue = 0.00458; mean CPM = 47.27; succinate-CoA ligase, ADP-forming, beta subunit" ID="ID_621994748" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SDHD: 1.2-fold Up; FDR = 0.042; PValue = 0.0125; mean CPM = 45.06; succinate dehydrogenase complex, subunit D, integral membrane protein" ID="ID_1906528711" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IDH3B: 1.19-fold Up; FDR = 0.0429; PValue = 0.0128; mean CPM = 56.57; isocitrate dehydrogenase 3 (NAD+) beta" ID="ID_1273769024" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDHA1: 1.17-fold Down; FDR = 0.0855; PValue = 0.0291; mean CPM = 57.75; pyruvate dehydrogenase (lipoamide) alpha 1" ID="ID_1763398194" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IDH3G: 1.17-fold Down; FDR = 0.0935; PValue = 0.0324; mean CPM = 39.41; isocitrate dehydrogenase 3 (NAD+) gamma" ID="ID_712133697" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDK3: 1.4-fold Down; FDR = 0.107; PValue = 0.0383; mean CPM = 3.392; pyruvate dehydrogenase kinase, isozyme 3" ID="ID_333842323" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DLD: 1.16-fold Up; FDR = 0.12; PValue = 0.0435; mean CPM = 57.77; dihydrolipoamide dehydrogenase" ID="ID_1134402922" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDHX: 1.11-fold Down; FDR = 0.373; PValue = 0.177; mean CPM = 27.58; pyruvate dehydrogenase complex, component X" ID="ID_63737815" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IDH3A: 1.1-fold Up; FDR = 0.413; PValue = 0.202; mean CPM = 34.53; isocitrate dehydrogenase 3 (NAD+) alpha" ID="ID_310947405" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="IDH2: 1.09-fold Down; FDR = 0.441; PValue = 0.22; mean CPM = 163.1; isocitrate dehydrogenase 2 (NADP+), mitochondrial" ID="ID_606965390" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SDHC: 1.08-fold Up; FDR = 0.489; PValue = 0.251; mean CPM = 54.35; succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa" ID="ID_221589439" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000007456: 1.15-fold Up; FDR = 0.687; PValue = 0.397; mean CPM = 3.871; Uncharacterized protein" ID="ID_865349240" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SDHB: 1.06-fold Up; FDR = 0.704; PValue = 0.411; mean CPM = 53.76; succinate dehydrogenase complex, subunit B, iron sulfur (Ip)" ID="ID_1170275499" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDP1: 1.06-fold Down; FDR = 0.734; PValue = 0.435; mean CPM = 31.76; pyruvate dehyrogenase phosphatase catalytic subunit 1" ID="ID_1968587133" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000012414: 1.62-fold Up; FDR = 0.794; PValue = 0.491; mean CPM = 0.8680; Uncharacterized protein" ID="ID_1375754816" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="DLAT: 1.03-fold Up; FDR = 0.903; PValue = 0.659; mean CPM = 48.33; dihydrolipoamide S-acetyltransferase" ID="ID_293235234" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="ENSMMUP00000036539: 1.04-fold Down; FDR = 1; PValue = 0.924; mean CPM = 1.052; Uncharacterized protein" ID="ID_697049741" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="PDHA2: 1.08-fold Down; FDR = 1; PValue = 0.965; mean CPM = 0.7976; pyruvate dehydrogenase (lipoamide) alpha 2" ID="ID_1965099340" CREATED="1400535622212" MODIFIED="1400535622212"/>
- <node TEXT="SUCLG1: No Change; FDR = 1; PValue = 0.986; mean CPM = 69.44; succinate-CoA ligase, alpha subunit" ID="ID_724363486" CREATED="1400535622212" MODIFIED="1400535622212"/>
- </node>
- </node>
- </node>
- </node>
- </map>
|
