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- ## My thesis
- - [My thesis](thesis-final.pdf): *Bioinformatic analysis of complex,
- high-throughput genomic and epigenomic data in the context of CD4⁺
- T-cell differentiation and diagnosis and treatment of transplant
- rejection*
- - [Slides for my defense talk](defense-slides.pdf): The slides for
- my dissertation defense, mainly covering Chapter 2 of my thesis
- ## Interesting sub-folders
- Each folder showcases a different project or aspect of my work in the
- Salomon lab.
- - [`Teaching`](Teaching): Teaching materials for my lecture and lab on
- introductory RNA-seq analysis
- - [`CD4`](CD4): Examples relating to my CD4 memory RNA-seq & ChIP-seq
- project
- - [`450k`](450k): Examples relating to analysis of Illumina 450k DNA
- methylation arrays
- - [`Pathways`](Pathways): Examples of gene set and pathway analysis
- for RNA-seq data
- - [`globin`](globin): Examples of my work in demonstrating the
- performance of a new globin blocking protocol for RNA-seq of blood
- tissues
- - [`fRMA`](fRMA): Examples and code from my work creating a custom
- frozen RMA reference to provide a stable normalization for machine
- learning applications
- ## Presentations
- - [`DGE Presentation.pdf`](DGE Presentation.pdf): comparing edgeR,
- DESeq, and limma on both a conceptual and practical level
- - [`Advanced RNA-seq Analysis.pdf`](Advanced RNA-seq Analysis.pdf): On
- the advanced features provided by limma for RNA-seq analysis
- - [`Reproducible Workflow Presentation.pdf`](Reproducible Workflow
- Presentation.pdf): Showcases the use of
- [Snakemake](https://snakemake.readthedocs.io/en/stable/) for
- building a reproducible analysis
- ## Other files
- - [`Classifier Math Write-up.pdf`](Classifier Math Write-up.pdf): A
- short write-up to explain the mathematical principles behind the
- classifier method used in a machine learning project
- - [`blockbuster-pipeline.R.html`](blockbuster-pipeline.R.html): R code
- for clustering small RNA reads into clusters
- using
- [Blockbuster](http://hoffmann.bioinf.uni-leipzig.de/LIFE/blockbuster.html)
- - [`mdsplots-multidim.pdf`](mdsplots-multidim.pdf): A PCA plot of RNA-seq
- data for *C. elegans* samples with and without a drug that retards
- the aging process, demonstrating smaller age-related changes with
- the drug
- (for [this paper](https://elifesciences.org/content/4/e08833))
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