Typically the first limiting important amino acid in progress and production. These carbonyl and hydroxyl oxygens have been proposed to facilitate the switch of the methyl group throughout catalysis sixteen , 21 , 24 In addition, tyrosine residues within the lysine-binding clefts of SET7/9 (Tyr245 and Tyr305) and DIM-5 (Tyr178) hydrogen-bond to the lysine ε-amino group, aligning it for a methyltransfer with AdoMet (Figure 4b,c ).

Pauling L: Speech at Pure Meals Exposition, March 29, 1982, reported in Natural Foods Merchandiser, June 1982, p.sixty five.

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