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Nandrolone: Uses, Benefits & Side Effects
What is nandrolone?
Nandrolone is a synthetic anabolic steroid derived from testosterone, first developed in the 1960s for therapeutic uses such as treating anemia, osteoporosis and muscle wasting conditions. In its most common form, nandrolone decanoate (often marketed under brand names like Deca-Durabolin), it is administered by intramuscular injection and slowly releases into the bloodstream over several weeks. The compound promotes protein synthesis, nitrogen retention and cell proliferation—effects that are beneficial in clinical settings but also attractive to athletes seeking performance gains.
How does nandrolone differ from other steroids?
Unlike testosterone itself, nandrolone lacks a 17β-hydroxyl group that makes it more resistant to aromatase conversion into estrogen. Consequently, users experience fewer gynecomastia and water‑retention side effects compared to estrogens or anabolic–androgenic steroids (AAS) with high aromatization rates. However, nandrolone can still be metabolized to 5α‑reduced derivatives that bind androgen receptors strongly, providing significant anabolic activity.
Why do athletes use it?
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